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631 Study Matches
Active Temperature Management After Cardiac Surgery and Its Effect on Postoperative Cognitive Dysfunction
Rebecca Collen, MBA - rebecca.collen@vcuhealth.org
Yajnik, Vishal
Phase 2
NCT03947671
HM20015426
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Inclusion Criteria:
• scheduled coronary artery bypass graft surgery patients, with or without valve surgery
• patients able to give informed consent
Exclusion Criteria:
• age < 20 years or > 89 years
• patients with unscheduled CABG +/- valve surgery (i.e. emergency surgery)
• deformity or skin condition of chest or thighs that would interfere with the successful placement of Rapr Round® vest and leg wraps
• patients presenting to the ICU postoperatively with a fever ≥ 38.3
• patients with planned intraoperative circulatory arrest
• prisoners
• pregnant patients
• patients with symptomatic cerebrovascular disease, specifically residual motor deficits, expressive or receptive aphasia from prior stroke or cerebrovascular accident
Device: Rapr Rounds Hyper/Hypothermia Wraps, Drug: Acetaminophen
Cardiac Surgery, Post-operative Cognitive Dysfunction, Fever
temperature regulation
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Study Locations
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Rebecca Collen, MBA - (rebecca.collen@vcuhealth.org) Jessica Mason, MPH - (jessica.mason1@vcuhealth.org) |
Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
BMS Study Connect Contact Center www.BMSStudyConnect.com - Clinical.Trials@bms.com
McCarty, John, M.
Phase 2/Phase 3
NCT03435796
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Inclusion Criteria:
• Received at least one gene-modified (GM) T-cell infusion in a previous Celgene sponsored or Celgene alliance partner-sponsored study, and have discontinued, or completed the post-treatment follow-up period in the parent treatment protocol, as applicable.
• Must understand and voluntarily sign an Informed Consent Form/Informed Assent Form prior to any study-related assessments/procedures being conducted.
Exclusion Criteria:
Not Applicable
Other protocol-defined inclusion/exclusion criteria apply
Genetic: Gene-modified (GM) T cell therapy
Neoplasms
Long-term follow up, Gene-Modified T Cells, CAR T Cell
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Show 217 locations
Study Locations
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| Location | Contacts |
|---|---|
| Allgemeinen Krankenhaus (AKH) Wien - Medizinische Universitaet Wien Wien, | |
| Arizona Cancer Center Scottsdale, Arizona | |
| Avera Cancer Institute Sioux Falls, South Dakota | |
| Azienda Ospedaliera Citta della Salute e della Scienza di Torino Torino, Piedmont | |
| Azienda Ospedaliero Universitaria Di Bologna Policlinico Sorsola Malpighi Bologna, | |
| Azienda Sanitaria Ospedaliera San Giovanni Battista Molinette Turin, | |
| Banner MD Anderson Cancer Center Gilbert, Arizona | |
| Baptist Cancer Center Memphis, Tennessee | |
| Baylor Scott and White Health Temple, Texas | |
| CHRU de Lille France Lille Cedex, | |
| CHU Hotel Dieu Nantes Cedex 01, | |
| CHU La Miletrie Poitiers Cedex, | |
| CHU Montpellier - Hôpital Saint Eloi Montpellier CEDEX 5, | |
| CIUSSS de l'Est-de-l'Ile-de-Montreal Montreal, Quebec | |
| Cancer Center Of Kansas Wichita, Kansas | |
| Cedars-Sinai Medical Center Los Angeles, California | |
| Centre Hospitalier Lyon-Sud Pierre-Bénite, Auvergne-Rhône-Alpes | |
| Charite -Universitätsmedizin Berlin Berlin, | |
| Christie Hospital NHS Trust Manchester, | |
| City of Hope Duarte, California | |
| Cleveland Clinic Foundation Cleveland, Ohio | |
| Cleveland Clinic Foundation Cleveland, Ohio | Brian Hill, Site 01062 |
| Clinica Universidad de Navarra Pamplona, Navarre | |
| Colorado Blood Cancer Institute Denver, Colorado | |
| Columbia University Medical Center/New York-Presbyterian Hospital New York, New York | |
| Dana-Farber/Mass General Brigham Cancer Care, Inc Boston, Massachusetts | |
| Duke University Medical Center Durham, North Carolina | |
| Erasmus Medical Center - Daniel den Hoed Rotterdam, | |
| Florida Hospital Transplant Institute Orlando, Florida | |
| Fondazione IRCCS Istituto Nazionale dei Tumori Milan, | |
| Fondazione Monza e Brianza per il Bambino e la sua Mamma (MBBM) Monza, | |
| Fox Chase Cancer Center Philadelphia, Pennsylvania | |
| Franciscan St. Francis Health - Indiana Blood and Marrow Transplantation (IBMT) Indianapolis, Indiana | |
| Fred Hutchinson Cancer Research Center Seattle, Washington | |
| Fred Hutchinson Cancer Research Center Seattle, Washington | Jordan Gauthier, Site 01110 |
| Froedtert Hospital BMT Medical College of Wisconsin Milwaukee, Wisconsin | |
| Froedtert Hospital BMT Medical College of Wisconsin Milwaukee, Wisconsin | Meera Mohan, Site 01178 |
| Gustave Roussy Villejuif, | |
| H. Lee Moffitt Cancer Center and Research Institute University of South Florida Tampa, Florida | |
| Hackensack University Medical Center Hackensack, New Jersey | |
| Helsinki University Central Hospital (HUCH) Helsinki, | |
| Hematology Oncology and clinical immunology / Heinrich-Heine-University Dusseldorf, | |
| Hematology and Oncology Associates of SC, LLC Greenville, South Carolina | |
| Hematology and Oncology Associates of SC, LLC Greenville, South Carolina | Saeeda Chowdhury, Site 01034 |
| Hokkaido University Hospital Sapporo, Hokkaido | |
| Hopital Robert Debre Reims, | |
| Hopital Saint Louis Paris, | |
| Hopitaux de La Timone Marseille, Bouches-du-Rhône | |
| Hospital 12 de Octubre Madrid, | |
| Hospital Infantil Universitario Nino Jesus Madrid, | |
| Hospital Saint Louis Paris, | |
| Hospital San Joan de Deu Barcelona Esplugues de Llobregat, | |
| Hospital Universitari Germans Trias i Pujol ICO Badalona Barcelona, | |
| Hospital Universitario Vall D Hebron Barcelona, | |
| Hospital Virgen del Rocio Seville, | |
| IN Univ Simon Cancer Center Indianapolis, Indiana | |
| IN Univ Simon Cancer Center Indianapolis, Indiana | Rafat Abonour, Site 01161 |
| Icahn School of Medicine at Mount Sinai New York, New York | |
| Illinois Cancer Specialists The Woodlands, Texas | |
| Inselspital Bern Bern, | |
| Institut Clinic de Nefrologia i Urologia - Hospital Clinic i Provincial de Barcelona Barcelona, | |
| Institut Paoli-Calmettes Marseille, Bouches-du-Rhône | |
| Institut Universitaire du Cancer de Toulouse - Oncopole Toulouse, Haute-Garonne | |
| Institute for Pediatric Hematology - Oncology, Leon Berard Cancer Center Lyon, | |
| Intermountain Healthcare - LDS Hospital Salt Lake City, Utah | |
| Istituto Clinico Humanitas Rozzano, | |
| Istituto Nazionale Per Lo Studio E La Cura Dei Tumori Fondazione Giovanni Pascale Napoli, | |
| Japan Red Cross Medical Center Shibuya-ku, | |
| Jichi Medical University Hospital Tochigi, | |
| Juravinski Cancer Centre Hamilton, Ontario | |
| Kansas University Medical Center Kansas City, Kansas | |
| Karmanos Cancer Center Wayne State University Detroit, Michigan | |
| Karmanos Cancer Center Wayne State University Detroit, Michigan | Abhinav Deol, Site 01025 |
| Karolinska University Hospital Huddinge Stockholm, | |
| Kings College Hospital London, | |
| Kinikum der Universitaeat zu Koeln Koeln, | |
| Kyushu University Hospital Fukuoka, | |
| LMU Klinikum der Universitat München, | |
| Levine Cancer Institute Charlotte, North Carolina | |
| Local Institution - 02301 Toronto, Ontario | Site 02301 |
| Local Institution - 03151 Koeln, | Site 03151 |
| Local Institution - 03153 Ulm, | Site 03153 |
| Local Institution - 03154 München, | Site 03154 |
| Local Institution - 03501 Würzburg, | Site 03501 |
| Local Institution - 04301 Rotterdam, | Site 04301 |
| Local Institution - 05351 Gent, | Site 05351 |
| Local Institution - 07602 Ancona, | Site 07602 |
| Local Institution - 08253 Sevilla, | Site 08253 |
| Local Institution - 08451 Barcelona, | Site 08451 |
| Local Institution - 08601 Madrid, | Site 08601 |
| Local Institution - 08701 Pamplona, | Site 08701 |
| Local Institution - 09201 Pierre-Benite CEDEX, | Site 09201 |
| Local Institution - 09203 Poitiers Cedex, | Site 09203 |
| Local Institution - 09206 Montpellier CEDEX 5, | Site 09206 |
| Local Institution - 09401 Nantes Cedex 01, | Site 09401 |
| Local Institution - 10502 Manchester Withington, | Site 10502 |
| Local Institution - 12101 Wien, | Site 12101 |
| Local Institution - 13203 Osaka, | Site 13203 |
| Local Institution - 13601 Chuo-ku, Tokyo | Site 13601 |
| Local Institution - 13602 Minato-ku, Tokyo | Site 13602 |
| Local Institution - 13802 Shimotsuke, | Site 13802 |
| Local Institution - 13805 Fukuoka, | Site 13805 |
| Local Institution - 13806 Sapporo-shi, Hokkaido | Site 13806 |
| Local Institution - 15001 Stockholm, | Site 15001 |
| Lombardi Cancer Center - Georgetown University Hospital Washington, District of Columbia | |
| Loyola University Medical Center Maywood, Illinois | |
| Massachusetts General Hospital / Dana-Farber Cancer Institute Boston, Massachusetts | |
| Massachusetts General Hospital / Dana-Farber Cancer Institute Boston, Massachusetts | Jeremy Abramson, Site 01012 |
| Massachusetts General Hospital / Dana-Farber Cancer Institute Boston, Massachusetts | Nikhil Munshi, Site 01107 |
| Mayo Clinic Rochester, Minnesota | |
| Mayo Clinic Rochester, Minnesota | Yi Lin, Site 01105 |
| Mayo Clinic Phoenix Phoenix, Arizona | |
| Medizinische Klinik II ZIM,Hamatologie Onkologie Uniklinik Frankfurt Frankfurt, | |
| Memorial Sloan Kettering Cancer Center New York, New York | |
| Morristown Memorial Hosp Morristown, New Jersey | |
| NYU Langone Laura and Isaac Perlmutter Cancer Center New York, New York | |
| National Cancer Center Hospital Tokyo, | |
| National Cancer Institute Bangkok, | |
| New York Oncology Hematology P.C. Albany, New York | |
| Northside Hospital, Inc Atlanta, Georgia | |
| Northwest Medical Specialties PLLC Tacoma, Washington | |
| Northwestern Memorial Hospital Chicago, Illinois | |
| Northwestern Memorial Hospital Chicago, Illinois | Reem Karmali, Site 01014 |
| Norton Cancer Institute Louisville Oncology Louisville, Kentucky | |
| Oncology Hematology Care, Inc. Cincinnati, Ohio | |
| Oregon Health and Science University OHSU Portland, Oregon | |
| Osaka City University Hospital Osaka, | |
| Oslo Universitetssykehus Oslo, | |
| Ospedale Pediatrico Bambino Gesu Roma, | |
| Ospedali Riuniti di Ancona Ancona, | |
| Princess Margaret Cancer Centre Toronto, Ontario | |
| Princess Maxima Center for Pediatric Oncology Utrecht, | |
| Providence Cancer Institute Southfield, Michigan | |
| Providence Portland Medical Center Portland, Oregon | |
| Providence Portland Medical Center Portland, Oregon | Stacy Lewis, Site 01028 |
| Regional Cancer Care Associates LLC East Brunswick, New Jersey | |
| Robert-Rössle-Klinik im HELIOS Klinikum Berlin-Buch Klinik für Hämatologie, Onkologie u. Tumorimmuno Berlin, | |
| Roswell Park Cancer Institute Buffalo, New York | |
| Rutgers Cancer Institute of New Jersey New Brunswick, New Jersey | |
| Sam Clinical Research Center San Antonio, Texas | |
| Sam Clinical Research Center San Antonio, Texas | Julio Cesar Alvarenga Thiebaud, Site 01211 |
| Sarah Cannon Research Inst Nashville, Tennessee | |
| Seattle Children's Hospital Seattle, Washington | |
| Sidney Kimmel Comp Cancer Center at Johns Hopkins Baltimore, Maryland | |
| Sidney Kimmel Comp Cancer Center at Johns Hopkins Baltimore, Maryland | Syed Abbas Ali, Site 01017 |
| Siteman Cancer Center Saint Louis, Missouri | |
| Somers Cancer Research Building Shirley Southampton, | |
| Stanford Cancer Center Palo Alto, California | |
| Sutter Hematology and Oncology Sacramento, California | |
| Swedish Cancer Institute Seattle, Washington | |
| Texas Oncology Dallas, Texas | |
| Texas Oncology - Baylor Charles A. Sammons Cancer Center Dallas, Texas | |
| Texas Oncology - Baylor Charles A. Sammons Cancer Center Dallas, Texas | Houston Holmes, Site 01180 |
| Texas Oncology, P.A. - Tyler Tyler, Texas | |
| Texas Oncology, P.A. - Tyler Tyler, Texas | Habte Yimer, Site 01054 |
| The Children's Hospital of Philadelphia Philadelphia, Pennsylvania | |
| The Leeds Teaching Hospitals NHS Trust - St James's University Hospital Leeds, | |
| The Mayo Clinic - Jacksonville, Davis-E Jacksonville, Florida | |
| The Mayo Clinic - Jacksonville, Davis-E Jacksonville, Florida | Sikander Ailawadhi, Site 01201 |
| Thomas Jefferson University Philadelphia, Pennsylvania | |
| Tokai University Hospital Iseharashi, Kanagawa | |
| Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital Bunkyō City, | |
| Tokyo Women's Medical University Hospital Shinjuku-ku, Tokyo, | |
| Toranomon Hospital Minato-ku, Tokyo | |
| UCL Cancer Institute London, | |
| UCLA Medical Centre-Santa Monica Santa Monica, California | |
| UPMC Cancer Pavillion Pittsburgh, Pennsylvania | |
| UPMC Cancer Pavillion Pittsburgh, Pennsylvania | Alison Sehgal, Site 01210 |
| UT Southwestern Medical Center Dallas, Texas | |
| UZ Gent Ghent, | |
| Universita La Sapienza Roma, | |
| Universitaetsklinikum Hamburg-Eppendorf Hamburg, | |
| Universitaetsklinikum Muenster Münster, | |
| Universitaetsklinikum Tuebingen Tübingen, Baden-Wurttemberg | |
| Universitario de Salamanca - Hospital Clinico Salamanca, | |
| Universitatsklinikum Carl Gustav Carus an der TU Dresden Dresden, | |
| Universitatsklinikum Heidelberg Heidelberg, | |
| Universitatsklinikum Wurzburg Medizinische Klinik und Poliklinik II Würzburg, | |
| University Hospital Leuven Leuven, | |
| University Hospital of Ulm Ulm, | |
| University Hospitals of Cleveland Cleveland, Ohio | |
| University of Alabama Birmingham Birmingham, Alabama | |
| University of Alabama Birmingham Birmingham, Alabama | Luciano Costa, Site 01171 |
| University of Calgary Calgary, | |
| University of California San Diego Moores Cancer Center La Jolla, California | |
| University of California, San Francisco- California San Francisco, California | |
| University of Chicago Medical Center Chicago, Illinois | |
| University of Colorado Cancer Center Aurora, Colorado | |
| University of Colorado Cancer Center Aurora, Colorado | Manali Kamdar, Site 01208 |
| University of Kentucky Lexington, Kentucky | |
| University of Maryland - Greenebaum Comprehensive Cancer Center Baltimore, Maryland | |
| University of Michigan Comprehensive Cancer Center Ann Arbor, Michigan | |
| University of Minnesota Minneapolis, Minnesota | |
| University of Nebraska Medical Center Omaha, Nebraska | |
| University of Nebraska Medical Center Omaha, Nebraska | Matthew Lunning, Site 01015 |
| University of Oklahoma Peggy and Charles Stephenson Cancer Center Oklahoma City, Oklahoma | |
| University of Pennsylvania Perelman Center for Advanced Medicine Philadelphia, Pennsylvania | |
| University of Pennsylvania Perelman Center for Advanced Medicine Philadelphia, Pennsylvania | Stephen Schuster, Site 01016 |
| University of Rochester James P. Wilmot Cancer Center Rochester, New York | |
| University of Texas- MD Anderson Houston, Texas | |
| University of Texas- MD Anderson Houston, Texas | Hun Ju Lee, Site 01013 |
| University of Utah - Huntsman Cancer Institute Salt Lake City, Utah | |
| University of Utah - Huntsman Cancer Institute Salt Lake City, Utah | Douglas Sborov, Site 01199 |
| University of Virginia Health System Charlottesville, Virginia | |
| University of Virginia Health System Charlottesville, Virginia | Indumathy Varadarajan, Site 01065 |
| University of Wisconsin Madison, Wisconsin | |
| University of Wisconsin Madison, Wisconsin | Natalie Callander, Site 01036 |
| Vancouver General Hospital Vancouver, British Columbia | |
| Virginia Commonwealth University Richmond, Virginia | |
| Virginia Oncology Associates Newport News, Virginia | |
| Vrije Universiteit Medisch Centrum (VUMC) Amsterdam, | |
| Weill Cornell Medicine / New York Presbyterian Hospital New York, New York | |
| Willamette Valley Cancer Institute Eugene, Oregon | |
| Winship Cancer Institute of Emory University Atlanta, Georgia | |
| Winship Cancer Institute of Emory University Atlanta, Georgia | Sagar Lonial, Site 01103 |
| Yale Cancer Center New Haven, Connecticut | |
| Yale Cancer Center New Haven, Connecticut | Iris Isufi, Site 01059 |
Effects of a Mindfulness Intervention in Caregivers of People With Dementia (CARING) (CARING)
Dzierzewski, Jospeh - dzierzewski@vcu.edu
Dzierzewski, Jospeh
N/A
NCT03857308
HM20011802
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Inclusion Criteria:
• English speaking
• Self-reporting informal caregivers of persons with dementia
Exclusion Criteria:
• Self-reported major depressive disorder with psychotic features
• History of schizophrenia
• Bipolar disorder
• Uncorrected severe sensory impairments or chronic debilitating health problems that could hinder participating in the interventions
• Previous MBSR training or regular meditative practice within previous 6 months
Behavioral: Mindfulness Training, Behavioral: Reappraisal Training
Caregivers, Burnout, Sleep
well-being, sleep, caregiver
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Study Locations
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Dzierzewski, Jospeh - (dzierzewski@vcu.edu) |
Estab Biomarkers and Clinical Endpoints in Myotonic Dystrophy Type 1 (END-DM1)
Jennifer Raymond - jennifer.raymond@vcuhealth.org
Johnson, Nicholas, E
N/A
NCT03981575
HM20014419
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Inclusion criteria:
* Age 18 to 70 (inclusive)
* Competent to provide informed consent
* Clinical diagnosis of DM1 based on research criteria1 or positive genetic test
* Comment: The clinical research criteria require myotonia, muscle weakness in a characteristic distribution, and history of similar findings in a first degree relative. Genetic testing confirmed the diagnosis of DM1 in \> 99% of individuals who satisfied these criteria.2
Exclusion criteria:
* Symptomatic renal or liver disease, uncontrolled diabetes or thyroid disorder, or active malignancy other than skin cancer.
* Current alcohol or substance abuse
* Concurrent enrollment in clinical trial for DM1, or participation in trial within 6 months of entry.
* Concurrent pregnancy or planned pregnancy during the course of the study.
* Concurrent medical condition that would, in the opinion of the investigator or clinical evaluator, compromise performance on study measures.
* Note: non-ambulatory participants are not excluded, but are limited to \<15% of enrollment.
Inclusion criteria for participants in the muscle biopsy sub-study:
• Of the 95 patients undergoing the tibialis anterior muscle biopsy, at least half will have at least moderate weakness of ankle dorsiflexion, defined as MRC score ≤ 4+. This is in order to obtain a muscle tissue sample in a person more severely affected with myotonic dystrophy. Approximately 10 patients at each site will undergo the muscle biopsy.
Exclusion criteria for 95 participants in the muscle biopsy sub-study:
* Known CTG repeat expansion size less than 100 repeats, unless there are clear cut signs of limb weakness and muscle wasting. This is in order to obtain a muscle tissue sample in a person more severely affected with myotonic dystrophy.
* Use of anticoagulant such as warfarin or a direct oral anticoagulant (e.g. dabigatran) due to the increased risk of bleeding.
* Use of aspirin or non-steroidal anti-inflammatory agents should be discontinued 3 days prior to the biopsy procedure, if possible.
* Platelet count \<50,000 (if known) due to the increased risk of bleeding.
* History of a bleeding disorder due to the increased risk of bleeding.
* Advanced wasting of tibialis anterior (TA) muscle that precludes needle muscle biopsy in order to ensure that a sample taken would be of muscle and not just fat and fascia.
* Previous muscle biopsy of either TA in order to provide muscle tissue samples of non-biopsied muscles.
Myotonic Dystrophy 1, DM1
Myotonic Dystrophy, END DM-1, Muscular Dystophy, DMCRN
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Study Locations
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| Location | Contacts |
|---|---|
| Centro Clinico Nemo Milan, | |
| Friedrich Baur Institute, Ludwig-Maximilians-Universität München München, | Benedikt Schoser - (benedikt.schoser@med.lmu.ede) Corinna Wirner-Piotrowski - (Corinna.Wirner@med.uni-muenchen.de) |
| Houston Methodist Neurological Institute Houston, Texas | Kadeesia Brown - (kbrown5@houstonmethodist.org) |
| Kansas University Medical Center Kansas City, Kansas | Rebecca Clay - (rclay@kumc.edu) Michaela Walker - (mwalker20@kumc.edu) |
| Ohio State University Columbus, Ohio | Kaneshia Hives - (Kaneshia.Hives@osumc.edu) Lischele Watkins - (lischele.watkins@osumc.edu) |
| Radboud University Medical Center Nijmegen, | Baziel vanEngelen - (Baziel.vanEngelen@radboudumc.nl) Monique Plieger - (Monique.Plieger@radboudumc.nl) |
| St. George's, University of London London, | Emma Matthews - (ematthew@sgul.ac.uk) |
| University College London London, | Chris Turner - (chris.turner7@nhs.net) Iqraa Afzal - (iqraa.afzal@nhs.net) |
| University of Auckland Auckland, | Neerja Singh - (neerja.singh@auckland.ac.nz) Miriam Rodrigues - (mrodrigues@adhb.govt.nz) |
| University of California, Los Angeles Los Angeles, California | Dennis Fernando - (DeFernando@mednet.ucla.edu) |
| University of California, San Diego La Jolla, California | Elizabeth Moreno - (e4moreno@health.ucsd.edu) Gabriella Penner - (gpenner@health.ucsd.edu) |
| University of Colorado - Denver Denver, Colorado | Alyssa Avilez - (alyssa.avilez@cuanschutz.edu) Brianna Blume - (brianna.blume@cuanschutz.edu) |
| University of Florida Gainesville, Florida | Whitney Miller - (whitney.miller@neurology.ufl.edu) Donovan Lott - (djlottpt@phhp.ufl.edu) |
| University of Iowa Iowa City, Iowa | Maegan Tyrrell - (maegan-tyrrell@uiowa.edu) Loraine Brenner - (loraine-brenner@uiowa.edu) |
| University of Rochester Rochester, New York | Jim Hilbert - (james_hilbert@urmc.rochester.edu) Jeanne Dekdebrun - (Jeanne_dekdebrun@urmc.rochester.edu) |
| Université de Sherbrooke Québec, | |
| Virginia Commonwealth University Richmond, Virginia | Carino Jennings - (Carino.Garza@vcuhealth.org) Jodie Howell - (jodie.howell@vcuhealth.org) |
Clinical Trial Readiness to Solve Barriers to Drug Development in FSHD (ReSolve)
Michaela Walker - mwalker20@kumc.edu
Johnson, Nicholas, E
N/A
NCT03458832
HM20014323
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Inclusion Criteria:
* Patients with genetically confirmed FSHD1 or clinical diagnosis of FSHD with characteristic findings on exam and an affected parent or offspring
* Patients with symptomatic limb weakness
* Patients must be able to walk 30 feet without the support of another person or assistance (canes, walking sticks, and braces allowed; no walker).
* If taking over the counter supplements, willing to remain consistent with supplement regimen throughout the course of the study
Exclusion Criteria:
* Patients with cardiac or respiratory dysfunction (deemed clinically unstable, or would interfere with safe testing, in the opinion of the Investigator)
* Patients with orthopedic conditions that preclude safe testing of muscle function
* Patients that regularly use available muscle anabolic/catabolic agents such as corticosteroids, oral testosterone or derivatives, or oral beta agonists
* Patients that have used an experimental drug in an FSHD clinical trial within the past 30 days
* Patients that are pregnant DIAGNOSTIC_TEST: FSHD-specific functional rating scale, DEVICE: Electrical Impedance Myography
Facioscapulohumeral Muscular Dystrophy
muscular dystrophy., FSHD
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Show 14 locations
Study Locations
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| Location | Contacts |
|---|---|
| CHU de Nice Nice, | |
| Centro Clinico Nemo Milan, | Caterina Lazzaro - (caterina.lazzaro@centrocliniconemo.it) Erica Di Natale - (erica.dinatale@centrocliniconemo.it) |
| Institut de Myologie Paris, | Thiziri Iassamen - (t.iassamen@institut-myologie.org) Smail Ait Mohand - (s.aitmohand@institut-myologie.org) |
| Kennedy Krieger Institute Baltimore, Maryland | |
| Ludwig-Maximilians-Universitat Munchen München, | Corrina Wirner-Piotrowski, MSc - (Corinna.Wirner@med.uni-muenchen.de) Natalia Garcia Angarita, MD - (Natalia.Garcia-Angarita@med.uni-muenchen.de) |
| Radboud Unviersity Nijmegen, | |
| The Ohio State University Columbus, Ohio | |
| University of California Los Angeles Los Angeles, California | |
| University of College London - Queens Square London, | Louise Germain - (l.germain@nhs.net) Iwona Skorupinska - (iwona.skorupinska@nhs.net) |
| University of Kansas Medical Center Kansas City, Kansas | |
| University of Rochester Medical Center Rochester, New York | |
| University of Utah Salt Lake City, Utah | |
| University of Washington Seattle, Washington | |
| Virginia Commonwealth University Richmond, Virginia |
A Phase 3 Study to Evaluate the Efficacy and Safety of MGL-3196 (Resmetirom) in Patients With NASH and Fibrosis (MAESTRO-NASH)
Kimberly Dorney, RN, MSN - info@madrigalpharma.com
Sanyal, Arun, J
Phase 3
NCT03900429
HM20016537
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Inclusion Criteria:
• Must be willing to participate in the study and provide written informed consent.
• Male and female adults ≥ 18 years of age.
• Suspected or confirmed diagnosis of NASH
• Metabolic risk factors and AST > 20 U/L
• Criteria consistent with liver fibrosis as defined as one of the following:
• Biochemical test for fibrosis OR
• Fibroscan test OR
• Historical liver biopsy with diagnosis of NASH with fibrosis Stage 2 or 3
• MRI-PDFF with increased fat fraction
• Biopsy-proven NASH (Baseline liver biopsy) based on a liver biopsy obtained within 24 weeks before anticipated date of randomization (if the biopsy is deemed acceptable for interpretation by the central reader) with fibrosis stage 1A, 1B, 2, or 3 on liver biopsy and NAS of ≥ 4 with a score of at least 1 in each of the following NAS components:
• Steatosis (scored 0 to 3)
• Ballooning degeneration (scored 0 to 2)
• Lobular inflammation (scored 0 to 3)
Exclusion Criteria:
• History of significant alcohol consumption for a period of more than 3 consecutive months within 1 year prior to Screening.
• Regular use of drugs historically associated with NAFLD
• History of bariatric surgery or intestinal bypass surgery within the 5 years prior to randomization or planned during the conduct of the study.
• Recent significant weight gain or loss
• HbA1c ≥ 9.0%.
• Glucagon-like peptide 1 [GLP-1] agonist, high dose Vitamin E (> 400 IU/day), or pioglitazone therapy unless stable dose for 24 weeks prior to biopsy.
• Presence of cirrhosis on liver biopsy defined as stage 4 fibrosis.
• Diagnosis of hepatocellular carcinoma (HCC).
• MELD score ≥12, as determined at Screening, unless due to therapeutic anti coagulation.
• Hepatic decompensation
• Chronic liver diseases other than NASH
• Active autoimmune disease
• Serum ALT > 250 U/L.
• Active, serious medical disease with a likely life expectancy < 2 years.
• Participation in an investigational new drug trial in the 60 days or 5 half-lives, whichever is longer.
• Any other condition which, in the opinion of the Investigator, would impede compliance, hinder completion of the study, compromise the well-being of the patient, or interfere with the study outcomes.
Drug: MGL-3196, Drug: Placebo
NASH - Nonalcoholic Steatohepatitis
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Study Locations
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| Location | Contacts |
|---|---|
| AZ Delta Campus Wilgenstraat Roeselare, West-Vlaanderen | |
| Abertawe Bro Morgannwg University Health Board Swansea, Wales | |
| Adobe Gastroenterology Tucson, Arizona | |
| Aintree University Hospitals NHS Foundation Trust Liverpool, | |
| Algemeen Ziekenhuis Maria Middelares Ghent, | |
| Alliance Clinical Research Poway, California | |
| Arkansas Gastroenterology North Little Rock, Arkansas | |
| Assistance Publique-Hôpitaux de Paris Hôpital Cochin Paris Cedex 14, Ile-de-France | |
| Associates in Gastroenterology Hermitage, Tennessee | |
| Austin Health Heidelberg, Victoria | |
| Aventiv Research - Columbus Columbus, Ohio | |
| Awasty Research Network Marion, Ohio | |
| Azienda Ospedaliera Papa Giovanni XXIII Bergamo, | Madrigal Investigator |
| Azienda Ospedaliera Universitaria Policlinico Gaetano Martino Messina, | |
| Azienda Ospedaliera Universitaria-Maggiore della Carità di Novara Novara, | |
| Azienda Ospedaliero - Universitaria Careggi Florence, | Madrigal Investigator |
| Azienda Ospedaliero Universitaria Policlinico Paolo Giaccone Palermo, | |
| Barts Health NHS Trust London, Greater London | |
| Belfast Health and Social Care Trust Belfast, Northern Ireland | |
| Berlin Clinical Research Center Berlin, | Madrigal Investigator |
| Bioclinica Research - Orlando Orlando, Florida | |
| Bioclinica Research - The Villages The Villages, Florida | |
| Bon Secours St. Mary's Hospital of Richmond Richmond, Virginia | |
| Brooke Army Medical Center Fort Sam Houston, Texas | |
| Békés Megyei Központi Kórház Dr. Réthy Pál Tagkórház Békéscsaba, Bekes | |
| Cambridge University Hospitals NHS Foundation Trust Cambridge, | |
| Cedars-Sinai Medical Center Los Angeles, California | Madrigal Investigator |
| Center Hospitalier Universitaire d'Angers Angers, Pays De La Loire | |
| Centre Hospitalier Regional Universitaire de Lille Lille, | |
| Centre Hospitalier Universitaire Amiens-Picardie Amiens, | Madrigal Investigator |
| Centre Hospitalier Universitaire Brugmann Laeken, | |
| Centre Hospitalier Universitaire Estaing Clermont-Ferrand, Aubergne | |
| Centre Hospitalier Universitaire Henri Mondor Créteil Cedex, Ile-de-France | |
| Centre Hospitalier Universitaire de Montpellier Montpellier Cedex 5, Languedoc-Roussillon | |
| Centre Hospitalier Universitaire de Nancy - Hôpital de Brabois Vandœuvre-lès-Nancy, | |
| Centre Hospitalier Universitaire de Nice Hôpital l'Archet Nice Cedex 3, Provence Alpes Cote D'Azur | |
| Centre Hospitalier Universitaire de Rennes Rennes, Ille-et-Vilaine | |
| Centre Hospitalier Universitaire de Toulouse - Hôpital Rangueil Toulouse Cedex, Midi-Pyrenees | |
| Charité Universitätsmedizin Berlin Berlin, | Madrigal Investigator |
| Charité Universitätsmedizin Berlin - Campus Mitte Berlin, | Madrigal Investigator |
| Chelsea and Westminster Hospital NHS Foundation Trust London, England | |
| Clinical Research - Chicago Chicago, Illinois | |
| Clinical Research US - Henderson Henderson, Nevada | |
| Clinical Trials of America West Monroe, Louisiana | |
| Cliniques Universitaires Saint-Luc Brussels, | |
| Colorado Springs Family Practice Colorado Springs, Colorado | |
| Complejo Hospitalario Torrecardenas Almería, | |
| Complejo Hospitalario de Pontevedra Pontevedra, | |
| Consorci Hospital General Universitari de València Valencia, | |
| Consultants for Clinical Research Cincinnati, Ohio | |
| Covenant Research Sarasota, Florida | |
| Cumberland Research Associates Fayetteville, North Carolina | |
| Dallas Research Center Dallas, Texas | |
| Debreceni Egyetem Kenézy Gyula Egyetemi Kórház Debrecen, Hajdu-Bihar | |
| Del-pesti Centrumkorhaz - Orszagos Hematologiai es Infektologiai Intezet Budapest, | |
| Desert Clinical Research Mesa, Arizona | |
| Doctor's Hospital at Renaissance McAllen, Texas | |
| Duke University Medical Center Durham, North Carolina | |
| EPIMED Berlin, | Madrigal Investigator |
| EUGASTRO Leipzig, Sachsen | Madrigal Investigator |
| East Valley Family Physicians Chandler, Arizona | |
| Emek Medical Center Afula, Northern District | |
| Excel Medical Clinical Trials Boca Raton, Florida | |
| Florida Research Institute Tampa, Florida | |
| Fondazione Epatocentro Ticino Lugano, | Madrigal Investigator |
| Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Milan, | |
| Fondazione Policlinico Universitario Agostino Gemelli Roma, | |
| Frankfurt Clinical Research Center Frankfurt am main, | Madrigal Investigator |
| Fresno Clinical Research Center Fresno, California | |
| Fundacion de Investigacion De Diego San Juan, | Madrigal Investigator |
| GI Research Institute Vancouver, British Columbia | Madrigal Investigator |
| GI Specialists of Georgia Marietta, Georgia | |
| Gastro One - Germantown - Centre Oak Way Germantown, Tennessee | |
| Gastrointestinal Associates - Knoxville Knoxville, Tennessee | |
| Gastrointestinal Associates and Endoscopy Center - Madison Flowood, Mississippi | |
| Hadassah University Hospital Ein Kerem Jerusalem, Jerusalem | |
| Holy Family Hospital Methuen, Massachusetts | |
| Hopital Avicenne Bobigny, | |
| Hopital Beaujon Clichy, | |
| Hopital de la Croix Rousse Lyon, | |
| Hospital General Universitario Gregorio Marañon Madrid, | |
| Hospital Universitari Vall d'Hebron Barcelona, | |
| Hospital Universitari i Politecnic La Fe de Valencia Valencia, | |
| Hospital Universitario Marqués de Valdecilla Santander, | |
| Hospital Universitario Puerta De Hierro - Majadahonda Majadahonda, M | |
| Hospital Universitario Ramon y Cajal Madrid, | |
| Hospital Universitario Virgen del Rocio Seville, | |
| Hospital de la Santa Creu i de Sant Pau Barcelona, | |
| Hospital del Mar - Parc de Salut Mar Barcelona, | |
| Hunter Holmes McGuire Veterans Administration Medical Center Richmond, Virginia | |
| Hôpital Dupuytren Limoges cedex, Limousin | |
| Hôpital Erasme Anderlecht, Brussels Capital | |
| Hôpital Jean-Minjoz Besançon, Franche-Comte | |
| Hôpital Universitaire Pitié Salpêtrière Paris, Île-de-France Region | |
| Imperial College Healthcare NHS Trust London, | |
| Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione (ISMETT) Palermo, | Madrigal Investigator |
| John Hunter Hospital New Lambton Heights, New South Wales | |
| Kansas City Research Institute Kansas City, Missouri | |
| Kansas Medical Clinic - Gastroenterology Topeka, Kansas | |
| Klinikum Klagenfurt am Wörthersee Klagenfurt, | |
| Klinikum Wels-Grieskirchen Wels, Upper Austria | Madrigal Investigator |
| Krankenanstalt Rudolfstiftung Wien, Vienna | |
| LMC/ Manna Research - Brampton Brampton, Ontario | |
| Lancashire Clinical Research Centre Chorley, England | |
| Landesklinik St. Veit Salzburg, | Madrigal Investigator |
| Leipzig Research Center Leipzig, | Madrigal Investigator |
| Les Hôpitaux Universitaires de Strasbourg - Hôpital Hautepierre Strasbourg, Alsace | |
| Liver Associates of Texas Houston, Texas | |
| Liver Center of Texas Dallas, Texas | |
| Liver Institute Northwest Seattle, Washington | Madrigal Investigator |
| Lucas Research Morehead City, North Carolina | |
| Magyarország Egészségügyi Szolgáltató - Gyula Gyula, Bekes | |
| Magyarország Research Center Budapest, Hajdu-Bihar | |
| Magyarország Research Center Budapest, Hajdu-Bihar | |
| Manchester Clinical Research Centre Manchester, England | |
| Mater Misericordiae South Brisbane, Queensland | |
| McMaster University Hamilton, Ontario | |
| Medizinische Universität Wien Vienna, | Madrigal Investigator |
| Merseyside Clinical Research Centre Liverpool, England | |
| Miami Dade Medical Research Institute Miami, Florida | |
| Midlands Clinical Research Centre Birmingham, England | |
| Monash Medical Centre Clayton, Victoria | |
| Mt. Sinai Medical Center New York, New York | |
| National Research Institute - Huntington Park Huntington Park, California | |
| National Research Institute - Los Angeles Los Angeles, California | |
| National Research Institute - Panorama City Panorama City, California | |
| Nature Coast Clinical Research Inverness, Florida | |
| Nepean Hospital Kingswood, New South Wales | |
| Norfolk and Norwich University Hospital Norwich, Norfolk | |
| North Teesside Clinical Research Centre Hardwick, England | |
| Northwestern Medical Faculty Foundation Chicago, Illinois | |
| Nottingham University Hospitals NHS Trust Nottingham, | |
| Nouvel Hopital Civil Strasbourg, | |
| Ochsner Medical Center New Orleans, Louisiana | |
| Ordensklinikum Linz GmbH Barmherzige Schwestern Linz, Upper Austria | |
| Ospedale casa sollievo della sofferenza San Giovanni Rotondo, | |
| Pinnacle Clinical Research Live Oak, Texas | Gail Hinkson |
| Pinnacle Clinical Research - Austin Austin, Texas | |
| Plano Research Center Plano, Texas | |
| Plymouth Hospitals NHS Trust Plymouth, | |
| Polo Universitario - L'Azienda Ospedaliera Luigi Sacco Milano, Milano | Madrigal Investigator |
| Polska Oddział w Częstochowie Częstochowa, | Madrigal Investigator |
| Polska Oddział w Gdansk Gdańsk, | Madrigal Investigator |
| Polska Oddział w Gdyni Gdynia, | Madrigal Investigator |
| Polska Oddział w Katowicach Katowice, | Madrigal Investigator |
| Polska Oddział w Poznaniu Poznań, | Madrigal Investigator |
| Polska Oddział w Warszawie Warszawa, | Madrigal Investigator |
| Polska Oddział w Wrocław Wrocław, | Madrigal Investigator |
| Polska Oddział w Łodz Łódź, | Madrigal Investigator |
| Portsmouth Hospitals NHS Trust Portsmouth, England | |
| Premier Medical Group - Clarksville Clarksville, Tennessee | |
| Progressive Medical Research Port Orange, Florida | |
| Rabin Medical Center Petah Tikva, | |
| Rambam Health Care Campus - Rambam Medical Center Haifa, | |
| Royal Adelaide Hospital Adelaide, South Australia | |
| Royal Brisbane and Women's Hospital Herston, Queensland | |
| Royal Free London NHS Foundation Trust Hampstead, | |
| Royal Perth Hospital Perth, Western Australia | |
| Royal Prince Alfred Hospital Camperdown, New South Wales | |
| Ruane Clinical Research Los Angeles, California | |
| SIBAmed Studienzentrum Leipzig, | Madrigal Investigator |
| Saint George's University Hospitals NHS Foundation Trust London, | |
| Saint Louis University St Louis, Missouri | |
| Saint Vincent's Hospital Sydney Darlinghurst, New South Wales | |
| Salt Lake City Research Center Murray, Utah | |
| San Antonio Research Center San Antonio, Texas | |
| San Fernando Valley Health Institute West Hills, California | |
| Shaare Zedek Medical Center Jerusalem, | |
| Sir Charles Gairdner Hospital Perth, | |
| Soroka University Medical Center Beersheba, | |
| South Denver Gastroenterology - Swedish Medical Center Office Englewood, Colorado | |
| South Shore Medical Arts Bridgewater, Nova Scotia | |
| South Texas Research Institute Edinburg, Texas | |
| Southern Therapy and Advanced Research Jackson, Mississippi | |
| Szabolcs-Szatmár-Bereg Megyei Kórházak és Egyetemi Oktatókórház Nyíregyháza, Szabolcs-Szatmar-Bereg | |
| Tandem Clinical Research Marrero, Louisiana | |
| Tel Aviv Sourasky Medical Center Tel Aviv, | |
| Texas Digestive Disease Consultants - Bay Area Gastroenterology Webster, Texas | |
| Texas Digestive Disease Consultants - Dallas Dallas, Texas | |
| Texas Digestive Disease Consultants - Fort Worth Fort Worth, Texas | |
| Texas Digestive Disease Consultants - Gastroenterology Associates - Baton Rouge Baton Rouge, Louisiana | |
| Texas Digestive Disease Consultants - San Marcos San Marcos, Texas | |
| Thames Valley Dedicated Research Centre Reading, England | Madrigal Investigator |
| The Alfred Hospital Melbourne, Victoria | |
| The Chaim Sheba Medical Center Ramat Gan, Central District | |
| The Hexham Clinic Hexham, Northumberland, England | |
| The Institute for Liver Health - Chandler Chandler, Arizona | |
| The Institute for Liver Health - Glendale Glendale, Arizona | |
| The Institute for Liver Health - Tucson Tucson, Arizona | |
| The Lady Davis Carmel Medical Center Haifa, | |
| The Liver Institute at Methodist Dallas Medical Center Dallas, Texas | |
| The Newcastle upon Tyne Hospitals NHS Foundation Trust Newcastle upon Tyne, | Madrigal Investigator |
| The Royal Melbourne Hospital Parkville, | |
| The Texas Liver Institute San Antonio, Texas | |
| The University of Chicago Medicine Chicago, Illinois | |
| The Wales Clinic Cardiff, Wales | |
| Toronto General Hospital - Clinical Trials Pharmacy Toronto, Ontario | Madrigal Investigator |
| Toronto Liver Center Toronto, Ontario | |
| Universita degli Studi di Roma La Sapienza - Umberto I Policlinico di Roma Roma, | Madrigal Investigator |
| Universitair Ziekenhuis Antwerpen Edegem, Brussels Capital | |
| Universitair Ziekenhuis Gent Ghent, | |
| Universitair Ziekenhuis Leuven Leuven, Flemish Brabant | |
| Universitair Ziekenhuis Leuven Leuven, Flemish Brabant | |
| Universitatsspital Bern Bern, | Madrigal Investigator |
| Universitatsspital Zurich Zurich, | Madrigal Investigator |
| University Hospitals Birmingham NHS Foundation Trust Edgbaston, Birmingham | |
| University of Alberta Edmonton, Alberta | Madrigal Investigator |
| University of Calgary Liver Unit Calgary, | |
| University of California San Diego La Jolla, California | |
| University of Florida Hepatology Research at CTRB Gainesville, Florida | |
| University of Kansas Medical Center Research Institute Kansas City, Kansas | |
| University of Virginia Health System Charlottesville, Virginia | |
| Universitätsklinikum Frankfurt Frankfurt, | Madrigal Investigator |
| Universitätsklinikum Würzburg Würzburg, | Madrigal Investigator |
| Universitätsklinikum des Saarlandes Homburg/Saar, | Madrigal Investigator |
| Virginia Commonwealth University Richmond, Virginia | |
| Walter Reed National Military Medical Center Bethesda, Maryland | |
| Wasatch Peak Family Practice Layton, Utah | |
| Western Galilee Hospital-Nahariya Nahariya, Northern District | |
| Westmead Hospital Sydney, New South Wales | |
| William Osler Health System Brampton, Ontario | |
| Zentrum für Infektiologie Berlin Prenzlauer Berg Berlin, | Madrigal Investigator |
| Ziekenhuis Oost-Limburg' Genk, Limburg |
Postprandial Monocyte Maturation and Vascular Dysfunction Following High-Fat Meals - Study 1
Franco, Robert, "Lee" - francorl@vcu.edu
Franco, Robert, "Lee"
N/A
NCT03958734
HM20015510
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Inclusion Criteria:
• college-age: 18-30 years old
• normal fasting triglyceride (<150 mg/dL) (American College of Sports Medicine Guidelines for Exercise Testing and Prescription, 10th Edition).
• normal body composition: % body fat, males <25%, females <32% (American College of Sports Medicine Guidelines for Exercise Testing and Prescription, 10th Edition)
• self-reported engagement in moderate-vigorous intensity physical activity and/or an exercise training regimen OR self-reported low physical activity and no engagement in an exercise training regimen (International Physical Activity Questionnaire)
• low cardiorespiratory fitness (VO2peak; male: =<45 mL/kg/min; female: =<35 mL/kg/min; categorized as =40th percentile by ACSM Guidelines for Exercise Testing and Prescription, 10th Edition; 44, 45, 46, 47) OR high cardiorespiratory fitness (VO2peak; male: =55 mL/kg/min; female: 45 mL/kg/min; categorized as =70th percentile by ACSM Guidelines for Exercise Testing and Prescription, 10th Edition; 44, 45, 46, 47) f.) for female participants, presence of a normal, monthly menstrual cycle with or without prescribed contraceptive methods. .
Exclusion Criteria:
• presence of diagnosed cardiovascular, metabolic, or renal disease or dysfunction
• presence of signs and symptoms suggestive of cardiovascular, metabolic, or renal disease
• presence of musculoskeletal injury
• pregnancy
• history of smoking
• engagement in an abnormal eating behavior
• unable to communicate effectively in English
• moderate cardiorespiratory fitness (VO2peak; male: 46-54 mL/kg/min; female: 36-44 mL/kg/min)
• elevated or high fasting triglycerides (>150 mg/dL)
• absence of a normal, monthly menstrual cycle with or without prescribed contraceptive methods
Other: High-fat meal
Cardiovascular Risk Factor, Lipemia, Diseases of Circulatory System (390-459)
Vascular Dysfunction
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia |
Neuroblastoma Maintenance Therapy Trial (NMTT)
BCC Enroll - BCCEnroll@pennstatehealth.psu.edu
Gowda, Madhu, S
PHASE2
NCT02679144
HM20015342
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Inclusion Criteria:
* All patients must have a pathologically confirmed diagnosis of neuroblastoma, \< 30.99 years of age and classified as high risk at the time of diagnosis. Exception: patients who are initially diagnosed as non-high-risk neuroblastoma, but later converted (and/or relapsed) to high risk neuroblastoma are also eligible.
* All patients must be in complete remission (CR):
• No evidence of residual disease on scan
• No evidence of disease metastatic to bone marrow. * Specific Criteria by Stratum: Stratum 1/1B: All patients must have completed standard upfront therapy that replicates treatment which patients who were enrolled on ANBL0032 received, including: intensive induction chemotherapy and (if feasible) resection of primary tumor, followed by: consolidation with high-dose chemotherapy with stem cell transplant and radiotherapy, followed by: immunotherapy with Ch14.18/IL-2/GM-CSF (dinutuximab) and retinoic acid;. All subjects on Stratum 1/B must have also met the following criteria: • A pre-transplant disease status evaluation that met International Neuroblastoma Response Criteria (INRC) for CR (complete response), VGPR (very good partial response), or PR (partial response) for primary site, soft tissue metastases and bone metastases. Patients who meet those criteria must also meet the protocol-specified criteria for bone marrow response prior to transplant as outlined below: No more than 10% tumor involvement (based on total nucleated cellular content) seen on any specimen from a bilateral bone marrow aspirate/biopsy. Stratum 2: Neuroblastoma that is in first complete remission following standard upfront therapy different from that described for Stratum 1. Stratum 3: Neuroblastoma that failed to have a response of at least PR following induction chemotherapy and surgical resection of the primary tumor, but that has achieved CR following additional therapy. Stratum 4: Patients who have achieved a second or subsequent CR following relapse(s). * Pre-enrollment tumor survey: Prior to enrollment on this study, a determination of mandatory disease staging must be performed: * Tumor imaging studies including * Bilateral bone marrow aspirates and biopsy * This disease assessment is required for eligibility and preferably should be done within 2 weeks prior to enrollment, but must be done within a maximum of 4 weeks before enrollment. * Timing from prior therapy: Stratum 1/1B: Enrollment no later than 60 days after completion of upfront therapy, (last dose of cis-retinoic acid) with a maximum of 6 cycles of cis-retinoic acid maintenance therapy. Stratum 2, 3 and 4: Enrollment no later than 60 days from last dose of the most recent therapy. * Patients must have a Lansky or Karnofsky Performance Scale score of \> 50% and patients must have a life expectancy of ≥ 2 months. * All clinical and laboratory studies for organ functions to determine eligibility must be performed within 7 days prior to enrollment unless otherwise indicated below. * Patients must have adequate organ functions at the time of registration: * Hematological: Total absolute phagocyte count ≥1000/μL * Liver: Subjects must have adequate liver function * Renal: Adequate renal function * Females of childbearing potential must have a negative pregnancy test. Patients of childbearing potential must agree to use an effective birth control method. Female patients who are lactating must agree to stop breast-feeding. * Written informed consent in accordance with institutional and FDA (food and drug administration) guidelines must be obtained from all subjects (or patients' legal representative).
Exclusion Criteria:
* BSA (Body Surface Area) of \<0.25 m2.
* Investigational Drugs: Subjects who are currently receiving another investigational drug are excluded from participation.
* Anti-cancer Agents: Subjects who are currently receiving other anticancer agents are not eligible. Subjects must have fully recovered from hematological and bone marrow suppression effects of prior chemotherapy.
* Infection: Subjects who have an uncontrolled infection are not eligible until the infection is judged to be well controlled in the opinion of the investigator.
* Subjects who, in the opinion of the investigator, may not be able to comply with the safety monitoring requirements of the study, or in whom compliance is likely to be suboptimal, should be excluded. DRUG: Difluoromethylornithine (DFMO)
Neuroblastoma
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Study Locations
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| Location | Contacts |
|---|---|
| Alberta Children's Hospital Calgary, Alberta | Sherry Qian - (Sherry.Qian@albertahealthservices.ca) |
| All Children's Hospital Johns Hopkins Medicine St. Petersburg, Florida | Emily Riffle - (eriffle2@jhmi.edu) |
| Arkansas Children's Hospital Little Rock, Arkansas | Susan Hall - (HallSF@archildrens.org) |
| Arnold Palmer Hospital for Children Orlando, Florida | Michelle Pellet - (Michelle.Pellett@orlandohealth.com) |
| Augusta University Health Augusta, Georgia | Kimberly Gray - (kigray@augusta.edu) |
| CHUQ Québec, Quebec | Valérie-Ève Julien - (Valerie-Eve.Julien@crchudequebec.ulaval.ca) |
| CIUSSS de l'Estrie-CHUS Sherbrooke, Quebec | Cassandra Leblanc Desrochers - (cassandra.leblanc-desrochers.ciussse-chus@ssss.gouv.qc.ca) |
| CancerCare Manitoba Winnipeg, Manitoba | Krista Mueller - (kmueller@cancercare.mb.ca) |
| Children's Hospital and Clinics of Minnesota Minneapolis, Minnesota | Nel Siemsen - (Nel.Siemsen@childrensmn.org) |
| Children's Hospital of the King's Daughters Norfolk, Virginia | Sabrina Wigginton - (Sabrina.Wigginton@chkd.org) |
| Children's Medical Center Dallas, Texas | Michelle Rivas - (michelle.rivas@childrens.com) |
| Children's Mercy Hospitals and Clinics Kansas City, Missouri | Nicole Harvey - (ndharvey@cmh.edu) |
| Cleveland Clinic Children's Cleveland, Ohio | Luba Platt - (PLATTL@ccf.org) |
| Connecticut Children's Hospital Hartford, Connecticut | Nicole McCracken - (NMccracken@connecticutchildrens.org) |
| Dell Children's Blood and Cancer Center Austin, Texas | Rhea Robinson, RN - (TXAUS-DL-SFCHemonc.research@ascension.org) |
| Duke University Durham, North Carolina | Diana Sedito - (diana.sedito@duke.edu) |
| Gina Martin St Louis, Missouri | Gina Martin, RN - (gina.martin@health.slu.edu) |
| Hackensack University Medical Center Hackensack, New Jersey | Sherri Mayans - (sherri.mayans@hmhn.org) |
| Hasbro Children's Hospital Providence, Rhode Island | Christopher Bouressa - (cbouressa@lifespan.org) |
| Helen DeVos Children's Hospital Grand Rapids, Michigan | Mary Beth Readwin - (mary.readwin2@corewellhealth.org) |
| Janesway Children's Health and Rehabilitation Centre St. John's, Newfoundland and Labrador | Bev Mitchell - (Beverlyj.mitchell@easternhealth.ca) |
| Kapiolani Medical Center for Women and Children Honolulu, Hawaii | Andrea Siu, MPH - (andrea.siu@kapiolani.org) |
| Kentucky Children's Hospital Lexington, Kentucky | Tammy Taylor - (ttayl2@email.uky.edu) |
| Levine Children's Hospital Charlotte, North Carolina | Jotnyce Green - (jontyce.green@atriumhealth.org) |
| Medical College of Wisconsin Milwaukee, Wisconsin | Ashley Hain - (ahain@childrenswi.org) |
| Medical University of South Carolina Charleston, South Carolina | Shanta Salzar, MD - (salzers@musc.edu) |
| Monroe Carrell Jr. Children's Hospital at Vanderbilt Nashville, Tennessee | Aida Constantinescu - (aida.constantinescu@vumc.org) |
| Montreal Children's Hospital Montreal, Quebec | Dominique Lafreniere - (Dominique.Lafreniere@MUHC.MCGILL.CA) |
| Nationwide Children's Hospital Columbus, Ohio | |
| New York University New York, New York | Anna Yaffe - (Anna.Yaffe@nyumc.org) |
| Penn State Milton S. Hershey Medical Center and Children's Hospital Hershey, Pennsylvania | Suzanne Treadway - (streadway@hmc.psu.edu) |
| Primary Children's Hospital Salt Lake City, Utah | Group Contact - (Pc-cog@imail.org) |
| Rady Children's Hospital San Diego, California | Franchesca Ramirez - (framirez@rchsd.org) |
| Randall Children's Hospital Portland, Oregon | Aaron White - (AJWHITE@lhs.org) |
| Rebecca McFall Chicago, Illinois | Jennifer Ward, MD - (jennifer.ward@aah.org) |
| Rocky Mountain Pediatric Hematology Denver, Colorado | Marlie Mounts - (Marlie.Mounts@HealthONEcares.com) |
| St. Joseph's Children's Hospital Tampa, Florida | Jennifer Manns, RN - (jennifer.manns@baycare.org) |
| St. Lukes Boise, Idaho | Callie Wiskus - (wiskusca@slhs.org) |
| Texas Children's Cancer and Hematology Centers Houston, Texas | Cara-Lee Fontaine - (clfontai@texaschildrens.org) |
| Tufts Medical Center Boston, Massachusetts | |
| UCSF Benioff Children's Hospital Oakland- Oakland, California | Group Contact - (PedOncRschOAK@ucsf.edu) |
| UHC Sainte-Justine Montreal, Quebec | Guillaume Leblanc - (guillaume.leblanc.hsj@ssss.gouv.qc.ca) |
| University of Alabama, Children's of Alabama Birmingham, Alabama | Bridget Tate - (btate@peds.uab.edu) |
| University of Florida Gainesville, Florida | Ashley Bayne - (abayne@UFL.EDU) |
| University of Louisville Louisville, Kentucky | Jennifer Miller - (Jennifer.Miller4@nortonhealthcare.org) |
| University of Massachusetts Medical School Worcester Worcester, Massachusetts | |
| Virginia Commonwealth University Richmond, Virginia | Mary Madu - (memadu@vcu.edu) |
Study of Nicotine for Pain Associated With Chemotherapy-Induced Peripheral Neuropathy
Cancer Prevention and Control Study Team - masseycpc@vcu.edu
Chen, Zhi-Jian
Phase 2
NCT04468230
HM20019616
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Inclusion Criteria:
• Clinically diagnosed peripheral sensory neuropathy defined as:
• Greater than Grade 1 peripheral sensory neuropathy using the CTCAE v5.0 grading scale
• Grade 1 Asymptomatic
• Grade 2 Moderate symptoms; limiting instrumental activities of daily living (ADL)
• Grade 3 Severe symptoms; limiting self-care ADL
• Grade 4 Life-threatening consequences; urgent intervention indicated
• Have a baseline CIPN PRO total sensory score ≥ 24.3 on a 19 to 76 scale using the EORTC QLQ-CIPN-20 questionnaire
• Have a CIPN-related neuropathic pain score ≥ 4 on a 0 to 10 scale using the Brief Pain Inventory-Short Form (BPI-SF) item 5
• Will not have used any nicotine or tobacco products (eg, cigarettes, electronic cigarettes, smokeless tobacco, or other nicotine replacement therapies) within 14 days prior to study treatment start date
• Eastern Cooperative Oncology Group (ECOG) performance status of 0, 1, or 2
• Not currently receiving any chemotherapy
• Have previously received platinum- and/or taxane-based chemotherapy treatments and have persistent pain at least 3 months after completion of treatments.
• Willing and able to comply with study procedures and visit schedule.
• Willing to abstain from all tobacco/nicotine product use during study treatment and 30-day follow-up period.
• Ability to self-apply or have the patch applied at home daily.
• Ability to understand and the willingness to sign a written informed consent document
Exclusion Criteria:
• History of pre-existing peripheral sensory neuropathies related to the following:
• Autoimmune disease
• B12/folate deficiency
• Diabetes Mellitus
• Human immunodeficiency virus (HIV)
• Hyper/hypothyroidism
• Monoclonal gammopathy of undetermined significance or multiple myeloma
• History of receiving other types of neurotoxic chemotherapy drugs (eg, vinca alkaloids, bortezomib, thalidomide)
• Current or prior pheochromocytoma
• History of or active or clinically significant cardiac disease including any of the following:
• Unstable angina (eg, anginal symptoms at rest) or onset of angina within 3 months prior to initiating study treatment
• Myocardial infarction diagnosed within 6 months prior to initiating study treatment
• Cardiac arrhythmias requiring anti-arrhythmic therapy other than beta blockers
• New York Heart Association (NYHA) class III or IV congestive heart failure
• Poorly controlled high or low blood pressure defined as:
• SBP ≥ 140; DBP ≥ 90
• SBP ≤ 90; DBP ≤ 60
• Regular use of the following medications:
• Varenicline
• Bupropion (ie, bupropion hydrochloride sustained release)
• Women will be excluded if they are breastfeeding or are pregnant (by urinalysis) within 14 days prior to the start of nicotine transdermal patch administration.
• Medical, psychological, or social condition that, in the opinion of the investigator, may increase the patient's risk or limit the patient's adherence with study requirements
Drug: Nicotine Transdermal Patch
Neuropathy, Peripheral Neuropathy, Neuropathic Pain, Chemotherapy-induced Peripheral Neuropathy
Nicotine, Peripheral Neuropathy
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Study Locations
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| Location | Contacts |
|---|---|
| VCU Community Memorial Healthcenter Richmond, Virginia | Adriane Holloway, RN - (aholloway4@vcu.edu) |
| Virginia Commonwealth University Richmond, Virginia | Kendra Rowe, RN - (masseycpc@vcu.edu) |
Vaccination With 6MHP, With or Without Systemic CDX-1127, in Patients With Stage II-IV Melanoma (Mel-65)
Samantha Schaeffer - SMS6WN@uvahealth.org
Poklepovic, Andrew, S
Phase 1/Phase 2
NCT03617328
HM20019005
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• Patients with stage IIB, IIC, III, or IV melanoma at original diagnosis or at restaging after recurrence, rendered clinically free of disease by surgery, other therapy, or spontaneous remission within 6 months prior to registration.
• Patients with small radiologic or clinical findings of an indeterminate nature may be eligible.
• Patients with high-risk stage IIA melanoma (by DecisionDx Melanoma test, Castle Biosciences, Inc., Friendswood, TX) may be eligible.
• Participants may have had cutaneous, uveal, mucosal primary melanoma, or an unknown primary melanoma. Diagnosis of melanoma must be confirmed by cytological or histological examination. Staging of cutaneous melanoma will be based on version 8 AJCC staging system.
• Participants who have had brain metastases will be eligible if all of the following are true:
• Each brain metastasis must have been completely removed by surgery or each unresected brain metastasis must have been treated with stereotactic radiosurgery.
• No brain metastasis is > 2 cm in diameter at the time of registration.
• Any neurologic symptoms attributable to brain metastases have returned to baseline.There is no evidence of new or enlarging brain metastases.
• The most recent surgical resections or gamma-knife therapy for malignant melanoma must have been completed ≥ 1 week and ≤ 6 months prior to registration.
• ECOG performance status of 0 or 1.
• Ability and willingness to give informed consent.
• Adequate organ function
• Age 18 years or older at registration. Main
• The following medications or treatments at any time within 4 weeks of registration:
• Chemotherapy
• Interferon (e.g. Intron-A®)
• Radiation therapy (Stereotactic radiotherapy, such as gamma knife, can be used ≥ 1 week and ≤ 6 months prior to registration)
• Allergy desensitization injections
• High doses of systemic corticosteroids
• Growth factors (e.g. Procrit®, Aranesp®, Neulasta®)
• Interleukins (e.g. Proleukin®)
• Any investigational medication
• Targeted therapies specific for mutated BRAF or for MEK
• Nitrosoureas within 6 weeks of registration.
• Checkpoint molecule blockade therapy within 12 weeks of registration.
• Known or suspected allergies to any component of the vaccine.
• Previous vaccination with 6MHP.
• Prior treatment with CDX-1127 or other CD27 agonistic antibody.
• Pregnancy.
• HIV positivity or evidence of active Hepatitis C virus.
• Female participants must not be breastfeeding.
• A medical contraindication or potential problem in complying with the requirements of the protocol in the opinion of the investigator.
• New York Heart Association classification as having Class III or IV heart disease.
• Uncontrolled diabetes, defined as having an HgbA1c > 8.5%.
• Prior autoimmune disorders requiring cytotoxic or immunosuppressive therapy, or autoimmune disorders with visceral involvement. Participants with an active autoimmune disorder requiring these therapies are also excluded.
• Participants with known addiction to alcohol or drugs who are actively taking those agents, or participants with recent (within 1 year) or ongoing illicit IV drug use.
• Participants who have received a live vaccine within 30 days of registration.
• Body weight < 110 pounds at registration, due to the amount and frequency with which blood will be drawn.
• Participants with prior autoimmune pneumonitis.
Inclusion Criteria:
• Patients with stage IIB, IIC, III, or IV melanoma at original diagnosis or at restaging after recurrence, rendered clinically free of disease by surgery, other therapy, or spontaneous remission within 6 months prior to registration.
• Patients with small radiologic or clinical findings of an indeterminate nature may be eligible.
• Patients with high-risk stage IIA melanoma (by DecisionDx Melanoma test, Castle Biosciences, Inc., Friendswood, TX) may be eligible.
• Participants may have had cutaneous, uveal, mucosal primary melanoma, or an unknown primary melanoma. Diagnosis of melanoma must be confirmed by cytological or histological examination. Staging of cutaneous melanoma will be based on version 8 AJCC staging system.
• Participants who have had brain metastases will be eligible if all of the following are true:
• Each brain metastasis must have been completely removed by surgery or each unresected brain metastasis must have been treated with stereotactic radiosurgery.
• No brain metastasis is > 2 cm in diameter at the time of registration.
• Any neurologic symptoms attributable to brain metastases have returned to baseline.There is no evidence of new or enlarging brain metastases.
• The most recent surgical resections or gamma-knife therapy for malignant melanoma must have been completed ≥ 1 week and ≤ 6 months prior to registration.
• ECOG performance status of 0 or 1.
• Ability and willingness to give informed consent.
• Adequate organ function
• Age 18 years or older at registration. Main
Exclusion Criteria:
• The following medications or treatments at any time within 4 weeks of registration:
• Chemotherapy
• Interferon (e.g. Intron-A®)
• Radiation therapy (Stereotactic radiotherapy, such as gamma knife, can be used ≥ 1 week and ≤ 6 months prior to registration)
• Allergy desensitization injections
• High doses of systemic corticosteroids
• Growth factors (e.g. Procrit®, Aranesp®, Neulasta®)
• Interleukins (e.g. Proleukin®)
• Any investigational medication
• Targeted therapies specific for mutated BRAF or for MEK
• Nitrosoureas within 6 weeks of registration.
• Checkpoint molecule blockade therapy within 12 weeks of registration.
• Known or suspected allergies to any component of the vaccine.
• Previous vaccination with 6MHP.
• Prior treatment with CDX-1127 or other CD27 agonistic antibody.
• Pregnancy.
• HIV positivity or evidence of active Hepatitis C virus.
• Female participants must not be breastfeeding.
• A medical contraindication or potential problem in complying with the requirements of the protocol in the opinion of the investigator.
• New York Heart Association classification as having Class III or IV heart disease.
• Uncontrolled diabetes, defined as having an HgbA1c > 8.5%.
• Prior autoimmune disorders requiring cytotoxic or immunosuppressive therapy, or autoimmune disorders with visceral involvement. Participants with an active autoimmune disorder requiring these therapies are also excluded.
• Participants with known addiction to alcohol or drugs who are actively taking those agents, or participants with recent (within 1 year) or ongoing illicit IV drug use.
• Participants who have received a live vaccine within 30 days of registration.
• Body weight < 110 pounds at registration, due to the amount and frequency with which blood will be drawn.
• Participants with prior autoimmune pneumonitis.
Biological: 6MHP, Drug: Montanide ISA-51, Drug: polyICLC, Drug: CDX-1127
Melanoma
peptide, vaccine, adjuvant, 6MHP, polyICLC, varlilumab, CDX-1127, Montanide ISA-51
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Show 2 locations
Study Locations
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| Location | Contacts |
|---|---|
| University of Virginia Charlottesville, Virginia | Samantha Schaeffer - (SMS6WN@uvahealth.org) |
| Virginia Commonwealth University Richmond, Virginia | Faith McFadden, RN, BSN - (mcfaddenfr@vcu.edu) Carrie Donovan, RN - (donovan2@vcu.edu) |
APOLLO Study
Baldecchi, Mary - mary.baldecchi@vcuhealth.org
Gupta, Gaurav
N/A
NCT03615235
HM20014432
Diseases of Genitourinary System (580-629)
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Study Locations
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Brigle, Nathaniel, W - (nathaniel.brigle@vcuhealth.org) |
Expanded Access Protocol for Boys With Duchenne Muscular Dystrophy
O'Hara, Kathryn, A - kathryn.ohara@vcuhealth.org
Harper, Amy
II
NCT03863119
HM20016492
drug: Vamorolone
Diseases of Nervous System and Sense Organs (320-389)
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Study Locations
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | O'Hara, Kathryn, A - (kathryn.ohara@vcuhealth.org) |
Improving Uptake of Genetic Cancer Risk Assessment in African American Women
Sheppard, Vanessa, B. - Vanessa.Sheppard@vcuhealth.org
Sheppard, Vanessa, B.
N/A
NCT04476654
HM20016234
Ovary, Breast
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Show 1 location
Study Locations
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Sheppard, Vanessa, B. - (Vanessa.Sheppard@vcuhealth.org) |
Safety, Tolerability, Pharmacokinetics of Single Dose of MT-3921 in Subjects with Acute SCI
Newcombe, Amy - amy.newcombe@vcuhealth.org
Cameron, Brian, M
I
NCT04096950
HM20017584
drug: Mt-3921
Injury and Poisoning (800-999)
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Show 1 location
Study Locations
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Newcombe, Amy - (amy.newcombe@vcuhealth.org) |
Fecal Microbiota Transplantation in Cirrhosis and Hepatic Encephalopathy
Brown, Diandra - diandra.brown@vcuhealth.org
Bajaj, Jasmohan
I/II
NCT03796598
HM20015322
drug: Fmt
Diseases of Digestive System (520-579)
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Study Locations
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | McGeorge, Sara - (mcgeorgesr@vcu.edu) |
Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer
Jennifer Beeler - jbeeler@swog.org
Martins, Renato
PHASE2
NCT03851445
HM20016188
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• 1 Registration Step 0:
• Patients who need the fresh biopsy must also submit whole blood for ctDNA testing (see Section 15.3). These patients must be registered to Step 0 to obtain a patient ID number for the submission. Patients registered to Step 0 are not registered to the LUNGMAP protocol. To participate in LUNGMAP, patients must be registered to Step 1 after evaluation of patient eligibility, including tumor tissue adequacy, per protocol Section 5.1, Step 1. Patients registered at Step 0 must use the same SWOG patient ID for registration at Step 1. Step 1:
• Patients must have pathologically proven non-small cell lung cancer (all histologic types) confirmed by tumor biopsy and/or fine-needle aspiration. Disease must be Stage IV as defined in Section 4.0, or recurrent. The primary diagnosis of non-small cell lung cancer should be established using the current WHO/IASLC-classification of Thoracic Malignancies. All histologies, including mixed, are allowed.
• Patients must either be eligible to be screened at progression on prior treatment or to be pre-screened prior to progression on current treatment. These criteria are:
• Screening at progression on prior treatment: To be eligible for screening at progression, patients must have received at least one line of systemic therapy for any stage of disease (Stages I-IV) and must have progressed during or following their most recent line of therapy. * For patients whose prior systemic therapy was for Stage I-III disease only (i.e. patient has not received any treatment for Stage IV or recurrent disease), disease progression on platinum-based chemotherapy must have occurred within one year from the last date that patient received that therapy. For patients treated with consolidation anti-PD-1 or anti-PD-L1 therapy for Stage III disease, disease progression on consolidation anti-PD-1 or anti-PD-L1 therapy must have occurred within one year from the date or initiation of such therapy. * For patients whose prior therapy was for Stage IV or recurrent disease, the patient must have received at least one line of a platinum-based chemotherapy regimen or anti-PD-1/PD-L1 therapy, alone or in combination (e.g. Nivolumab or Pembrolizumab).
• Pre-Screening prior to progression on current treatment: To be eligible for pre-screening, current treatment must be for Stage IV or recurrent disease and patient must have received at least one dose of the current regimen. Patients must have previously received or currently be receiving a platinum-based chemotherapy regimen or anti-PD-1/PD-L1 therapy, alone or in combination (e.g. Nivolumab or Pembrolizumab). Patients on first-line treatment are eligible upon receiving Cycle 1, Day 1 infusion. Note: Patients will not receive their sub-study assignment until they progress and the LUNGMAP Notice of Progression is submitted.
• Patients must have adequate tumor tissue available, defined as ≥ 20% tumor cells and ≥ 0.2 mm3 tumor volume. * The local interpreting pathologist must review the specimen. * The pathologist must sign the LUNGMAP Local Pathology Review Form confirming tissue adequacy prior to Step 1 registration. Patients must agree to have this tissue submitted to Foundation Medicine for common broad platform CLIA biomarker profiling, PD-L1, and c-MET IHC (see Section 15.2). If archival tumor material is exhausted, then a new fresh tumor biopsy that is formalin-fixed and paraffin-embedded (FFPE) must be obtained. Patients who need the fresh biopsy must also submit whole peripheral blood for ctDNA testing. A tumor block or FFPE slides 4-5 microns thick must be submitted. Bone biopsies are not allowed. If FFPE slides are to be submitted, at least 12 unstained slides plus an H\&E stained slide, or 13 unstained slides must be submitted. However, it is strongly recommended that 20 FFPE slides be submitted. Note: Previous next-generation DNA sequencing (NGS) will be repeated if done outside this study for sub-study assignment. Patients must agree to have any tissue that remains after testing retained for the use of sub-study Translational Medicine (TM) studies at the time of consent the patient is enrolled in.
• Patients with known EGFR sensitizing mutations, EGFR T790M mutation, ALK gene fusion, ROS 1 gene rearrangement, or BRAF V600E mutation are not eligible unless they have progressed following all standard of care targeted therapy. EGFR/ALK/ROS/BRAF testing is not required prior to Step 1 registration, as it is included in the Foundation One testing for screening/pre-screening.
• Patients must have Zubrod performance status 0-1 (see Section 10.2) documented within 28 days prior to Step 1 registration.
• Patients must be ≥ 18 years of age.
• Patients must also be offered participation in banking for future use of specimens as described in Section 15.0.
• Patients must be willing to provide prior smoking history as required on the LUNGMAP Onstudy Form.
• As a part of the OPEN registration process (see Section 13.4 for OPEN access instructions) the treating institution's identity is provided in order to ensure that the current (within 365 days) date of institutional review board approval for this study has been entered in the system.
• Patients must be informed of the investigational nature of this study and must sign and give written informed consent in accordance with institutional and federal guidelines.
• U.S. patients who can complete the survey and the interview by telephone or email in English must be offered participation in the S1400GEN Survey Ancillary Study if local institution's policies allow participants to receive the Amazon gift card (see Sections 15.7 and 18.5). Patients at institutions that cannot offer the survey must still participate in the main study.
DRUG: Screening Platform
Previously Treated Non-Small Cell Lung Cancer
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Study Locations
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| Location | Contacts |
|---|---|
| AMG Crystal Lake - Oncology Crystal Lake, Illinois | Site Public Contact - (advocateresearch@advocate.com) |
| AMG Libertyville - Oncology Libertyville, Illinois | Site Public Contact - (advocateresearch@advocatehealth.com) |
| Abbott-Northwestern Hospital Minneapolis, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Adams Cancer Center Gettysburg, Pennsylvania | |
| Addison Gilbert Hospital Gloucester, Massachusetts | |
| Adena Regional Medical Center Chillicothe, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| AdventHealth Hendersonville Hendersonville, North Carolina | Site Public Contact - (AMBER.WHEELER@AdventHealth.com) |
| AdventHealth Infusion Center Asheville Asheville, North Carolina | Site Public Contact - (AMBER.WHEELER@AdventHealth.com) |
| AdventHealth Infusion Center Haywood Clyde, North Carolina | Site Public Contact - (AMBER.WHEELER@AdventHealth.com) |
| AdventHealth Infusion Center Weaverville Weaverville, North Carolina | Site Public Contact - (AMBER.WHEELER@AdventHealth.com) |
| AdventHealth Porter Denver, Colorado | |
| Advocate Christ Medical Center Oak Lawn, Illinois | |
| Advocate Good Samaritan Hospital Downers Grove, Illinois | Site Public Contact - (Barbara.barhamand@advocatehealth.com) |
| Advocate Good Shepherd Hospital Barrington, Illinois | |
| Advocate Illinois Masonic Medical Center Chicago, Illinois | |
| Advocate Lutheran General Hospital Park Ridge, Illinois | |
| Advocate Outpatient Center - Aurora Aurora, Illinois | Site Public Contact - (ncorp@aah.org) |
| Advocate Sherman Hospital Elgin, Illinois | |
| Advocate South Suburban Hospital Hazel Crest, Illinois | |
| Alaska Breast Care and Surgery LLC Anchorage, Alaska | Site Public Contact - (AKPAMC.OncologyResearchSupport@providence.org) |
| Alaska Oncology and Hematology LLC Anchorage, Alaska | Site Public Contact - (AKPAMC.OncologyResearchSupport@providence.org) |
| Alaska Women's Cancer Care Anchorage, Alaska | Site Public Contact - (AKPAMC.OncologyResearchSupport@providence.org) |
| Allegiance Health Jackson, Michigan | Site Public Contact - (CTOResearch@hfhs.org) |
| Alliance for Childhood Diseases/Cure 4 the Kids Foundation Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Alta Bates Summit Medical Center-Herrick Campus Berkeley, California | Site Public Contact - (clinicalresearch@sutterhealth.org) |
| American Fork Hospital / Huntsman Intermountain Cancer Center American Fork, Utah | |
| AnMed Health Cancer Center Anderson, South Carolina | Site Public Contact - (rhonda.ballew@anmedhealth.org) |
| Anchorage Associates in Radiation Medicine Anchorage, Alaska | Site Public Contact - (AKPAMC.OncologyResearchSupport@providence.org) |
| Anchorage Oncology Centre Anchorage, Alaska | |
| Anchorage Radiation Therapy Center Anchorage, Alaska | |
| Ann M Wierman MD LTD Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Annie Penn Memorial Hospital Reidsville, North Carolina | Site Public Contact - (stacey.phelps@conehealth.com) |
| Armes Family Cancer Center Findlay, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Arnold Palmer Cancer Center Medical Oncology Norwin N. Huntingdon, Pennsylvania | |
| Arnot Ogden Medical Center/Falck Cancer Center Elmira, New York | |
| Ascension All Saints Hospital Racine, Wisconsin | Site Public Contact - (AWRI.Inquiry@Ascension.org) |
| Ascension Borgess Cancer Center Kalamazoo, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
| Ascension Borgess Hospital Kalamazoo, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
| Ascension Calumet Hospital Chilton, Wisconsin | Site Public Contact - (AWRI.inquiry@ascension.org) |
| Ascension Columbia Saint Mary's Hospital - Milwaukee Milwaukee, Wisconsin | Site Public Contact - (AWRI.Inquiry@Ascension.org) |
| Ascension Columbia Saint Mary's Hospital Ozaukee Mequon, Wisconsin | Site Public Contact - (AWRI.Inquiry@Ascension.org) |
| Ascension Medical Group Southeast Wisconsin - Mayfair Road Wauwatosa, Wisconsin | Site Public Contact - (AWRI.Inquiry@Ascension.org) |
| Ascension Mercy Hospital Oshkosh, Wisconsin | Site Public Contact - (AWRI.inquiry@ascension.org) |
| Ascension Saint Elizabeth Hospital Appleton, Wisconsin | Site Public Contact - (AWRI.inquiry@ascension.org) |
| Ascension Saint Francis - Reiman Cancer Center Franklin, Wisconsin | Site Public Contact - (AWRI.Inquiry@Ascension.org) |
| Ascension Saint Francis Hospital Milwaukee, Wisconsin | Site Public Contact - (AWRI.Inquiry@Ascension.org) |
| Ascension Southeast Wisconsin Hospital - Elmbrook Campus Brookfield, Wisconsin | Site Public Contact - (AWRI.Inquiry@Ascension.org) |
| Ascension Southeast Wisconsin Hospital - Franklin Franklin, Wisconsin | Site Public Contact - (AWRI.Inquiry@Ascension.org) |
| Ascension Southeast Wisconsin Hospital - Saint Joseph Campus Milwaukee, Wisconsin | Site Public Contact - (AWRI.Inquiry@Ascension.org) |
| Ascension Via Christi - Pittsburg Pittsburg, Kansas | |
| Ascension Via Christi Hospitals Wichita Wichita, Kansas | |
| Aspirus Cancer Care - James Beck Cancer Center Rhinelander, Wisconsin | Site Public Contact - (Beth.Knetter@aspirus.org) |
| Aspirus Cancer Care - Stevens Point Stevens Point, Wisconsin | Site Public Contact - (Beth.Knetter@aspirus.org) |
| Aspirus Cancer Care - Wisconsin Rapids Wisconsin Rapids, Wisconsin | |
| Aspirus Medford Hospital Medford, Wisconsin | Site Public Contact - (Beth.Knetter@aspirus.org) |
| Aspirus Regional Cancer Center Wausau, Wisconsin | |
| Atlanta VA Medical Center Decatur, Georgia | |
| Atrium Medical Center-Middletown Regional Hospital Franklin, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Augusta University Medical Center Augusta, Georgia | |
| Aultman Alliance Community Hospital Alliance, Ohio | |
| Aultman Health Foundation Canton, Ohio | Site Public Contact - (ClinicalReserachDept@aultman.com) |
| Aurora Bay Area Medical Group-Marinette Marinette, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora BayCare Medical Center Green Bay, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Cancer Care-Grafton Grafton, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Cancer Care-Kenosha South Kenosha, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Cancer Care-Milwaukee Milwaukee, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Cancer Care-Milwaukee West Wauwatosa, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Cancer Care-Racine Racine, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Cancer Care-Southern Lakes VLCC Burlington, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Health Care Germantown Health Center Germantown, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Health Center-Fond du Lac Fond du Lac, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Medical Center in Summit Summit, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Saint Luke's Medical Center Milwaukee, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Saint Luke's South Shore Cudahy, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Sinai Medical Center Milwaukee, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora West Allis Medical Center West Allis, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| BASS Medical Group - Lennon Walnut Creek, California | Site Public Contact - (brenna.lindsey@bassmedicalgroup.com) |
| BI-LO Charities Children's Cancer Center Greenville, South Carolina | |
| BJC Outpatient Center at Sunset Hills Sunset Hills, Missouri | |
| Banner University Medical Center - Tucson Tucson, Arizona | Site Public Contact - (UACC-IIT@uacc.arizona.edu) |
| Baptist Cancer Center-Grenada Grenada, Mississippi | Site Public Contact - (BCCclintrials@bmhcc.org) |
| Baptist Health Corbin Corbin, Kentucky | |
| Baptist Health Floyd New Albany, Indiana | Site Public Contact - (ctsucontact@westat.com) |
| Baptist Health Hamburg Lexington, Kentucky | |
| Baptist Health Hardin Elizabethtown, Kentucky | |
| Baptist Health Lexington Lexington, Kentucky | |
| Baptist Health Louisville Louisville, Kentucky | Site Public Contact - (Cbcresearch@bhsi.com) |
| Baptist Health Paducah Paducah, Kentucky | |
| Baptist Health Richmond Richmond, Kentucky | Site Public Contact - (ctsucontact@westat.com) |
| Baptist Memorial Hospital and Cancer Center-Collierville Collierville, Tennessee | Site Public Contact - (BCCclintrials@bmhcc.org) |
| Baptist Memorial Hospital and Cancer Center-Desoto Southhaven, Mississippi | Site Public Contact - (BCCclintrials@bmhcc.org) |
| Baptist Memorial Hospital and Cancer Center-Golden Triangle Columbus, Mississippi | Site Public Contact - (BCCclintrials@bmhcc.org) |
| Baptist Memorial Hospital and Cancer Center-Memphis Memphis, Tennessee | Site Public Contact - (BCCclintrials@bmhcc.org) |
| Baptist Memorial Hospital and Cancer Center-Oxford Oxford, Mississippi | Site Public Contact - (BCCclintrials@bmhcc.org) |
| Baptist Memorial Hospital and Cancer Center-Union County New Albany, Mississippi | Site Public Contact - (BCCclintrials@bmhcc.org) |
| Bay Area Hospital Coos Bay, Oregon | Site Public Contact - (cherie.cox@bayareahospital.org) |
| Bayhealth Hospital Kent Campus Dover, Delaware | Site Public Contact - (clinical_trials@bayhealth.org) |
| Bayhealth Hospital Sussex Campus Milford, Delaware | Site Public Contact - (clinical_trials@bayhealth.org) |
| Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center Houston, Texas | |
| Bayshore Community Hospital Holmdel, New Jersey | Site Public Contact - (ctsucontact@westat.com) |
| Baystate Medical Center Springfield, Massachusetts | Site Public Contact - (tamara.wrenn@baystatehealth.org) |
| Beebe Health Campus Rehoboth Beach, Delaware | Site Public Contact - (research@beebehealthcare.org) |
| Beebe Medical Center Lewes, Delaware | Site Public Contact - (research@beebehealthcare.org) |
| Beebe South Coastal Health Campus Millville, Delaware | Site Public Contact - (research@beebehealthcare.org) |
| Benefis Sletten Cancer Institute Great Falls, Montana | Site Public Contact - (mccinfo@mtcancer.org) |
| Bethesda North Hospital Cincinnati, Ohio | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Beverly Hospital Beverly, Massachusetts | |
| Bhadresh Nayak MD PC-Sterling Heights Sterling Heights, Michigan | |
| Billings Clinic Cancer Center Billings, Montana | Site Public Contact - (research@billingsclinic.org) |
| Billings Clinic-Cody Cody, Wyoming | Site Public Contact - (research@billingsclinic.org) |
| Blanchard Valley Hospital Findlay, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Bon Secours Cancer Institute at Reynolds Crossing Richmond, Virginia | Site Public Contact - (Anne_caramella@bshsi.org) |
| Bon Secours Memorial Regional Medical Center Mechanicsville, Virginia | Site Public Contact - (anne_carmellat@bshsi.org) |
| Bon Secours Richmond Community Hospital Richmond, Virginia | Site Public Contact - (anne_carmellat@bshsi.org) |
| Bon Secours Saint Francis Medical Center Midlothian, Virginia | Site Public Contact - (anne_carmellat@bshsi.org) |
| Bon Secours Saint Mary's Hospital Richmond, Virginia | Site Public Contact - (anne_carmellat@bshsi.org) |
| Bon Secours Westchester Emergency Center Midlothian, Virginia | Site Public Contact - (anne_carmellat@bshsi.org) |
| Boston Veteran's Affairs Medical Center Jamaica Plain, Massachusetts | Site Public Contact - (protocols@swog.org) |
| Boulder Community Foothills Hospital Boulder, Colorado | Site Public Contact - (info@westernstatesncorp.org) |
| Bozeman Health Deaconess Hospital Bozeman, Montana | Site Public Contact - (mccinfo@mtcancer.org) |
| Bronson Battle Creek Battle Creek, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
| Bronson Methodist Hospital Kalamazoo, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
| Bryn Mawr Hospital Bryn Mawr, Pennsylvania | Site Public Contact - (turzoe@mlhs.org) |
| CHI Health Good Samaritan Kearney, Nebraska | |
| CTCA at Southeastern Regional Medical Center Newnan, Georgia | |
| CTCA at Western Regional Medical Center Goodyear, Arizona | |
| California Pacific Medical Center-Pacific Campus San Francisco, California | Site Public Contact - (clinicalresearch@sutterhealth.org) |
| Cambridge Medical Center Cambridge, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Cancer Care Associates of York York, Pennsylvania | |
| Cancer Care Center of O'Fallon O'Fallon, Illinois | Site Public Contact - (morganthaler.jodi@mhsil.com) |
| Cancer Care Specialists of Illinois - Decatur Decatur, Illinois | Site Public Contact - (morganthaler.jodi@mhsil.com) |
| Cancer Care and Hematology-Fort Collins Fort Collins, Colorado | Site Public Contact - (protocols@swog.org) |
| Cancer Center at Saint Joseph's Phoenix, Arizona | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Cancer Center of Kansas - Chanute Chanute, Kansas | |
| Cancer Center of Kansas - Dodge City Dodge City, Kansas | |
| Cancer Center of Kansas - El Dorado El Dorado, Kansas | |
| Cancer Center of Kansas - McPherson McPherson, Kansas | |
| Cancer Center of Kansas - Newton Newton, Kansas | |
| Cancer Center of Kansas - Parsons Parsons, Kansas | |
| Cancer Center of Kansas - Pratt Pratt, Kansas | |
| Cancer Center of Kansas - Salina Salina, Kansas | |
| Cancer Center of Kansas - Wellington Wellington, Kansas | |
| Cancer Center of Kansas - Wichita Wichita, Kansas | |
| Cancer Center of Kansas - Winfield Winfield, Kansas | |
| Cancer Center of Kansas-Independence Independence, Kansas | |
| Cancer Center of Kansas-Kingman Kingman, Kansas | |
| Cancer Center of Kansas-Liberal Liberal, Kansas | |
| Cancer Center of Kansas-Manhattan Manhattan, Kansas | |
| Cancer Center of Kansas-Wichita Medical Arts Tower Wichita, Kansas | |
| Cancer Center of Western Wisconsin New Richmond, Wisconsin | Site Public Contact - (mmcorc@healthpartners.com) |
| Cancer Centers of Southwest Oklahoma Research Lawton, Oklahoma | |
| Cancer Hematology Centers - Flint Flint, Michigan | Site Public Contact - (wstrong@ghci.org) |
| Cancer Partners of Nebraska Lincoln, Nebraska | |
| Cancer Specialists of Tidewater Limited Chesapeake, Virginia | |
| Cancer Specialists of Tidewater-Suffolk Suffolk, Virginia | |
| Cancer Treatment Centers of America Tulsa, Oklahoma | |
| Cancer and Blood Specialists-Henderson Henderson, Nevada | Site Public Contact - (research@sncrf.org) |
| Cancer and Hematology Centers of Western Michigan - Norton Shores Norton Shores, Michigan | |
| Carle Cancer Center Urbana, Illinois | Site Public Contact - (Research@carle.com) |
| Carle Physician Group-Effingham Effingham, Illinois | Site Public Contact - (Research@carle.com) |
| Carle Physician Group-Mattoon/Charleston Mattoon, Illinois | Site Public Contact - (Research@carle.com) |
| Carle at The Riverfront Danville, Illinois | Site Public Contact - (Research@Carle.com) |
| Carlisle Regional Cancer Center Carlisle, Pennsylvania | Site Public Contact - (protocols@swog.org) |
| Caro Cancer Center Caro, Michigan | |
| Carson Tahoe Regional Medical Center Carson City, Nevada | Site Public Contact - (research@sncrf.org) |
| Case Western Reserve University Cleveland, Ohio | |
| Castle Medical Center Kailua, Hawaii | Site Public Contact - (protocols@swog.org) |
| Cedars Sinai Medical Center Los Angeles, California | |
| Cedars-Sinai Cancer - Tarzana Tarzana, California | |
| Centra Alan B Pearson Regional Cancer Center Lynchburg, Virginia | Site Public Contact - (Kevin.Patel@centrahealth.com) |
| Central Care Cancer Center - Great Bend Great Bend, Kansas | Site Public Contact - (aroland@kccop.org) |
| Central Ohio Breast and Endocrine Surgery Gahanna, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Central Vermont Medical Center/National Life Cancer Treatment Berlin Corners, Vermont | |
| Centralia Oncology Clinic Centralia, Illinois | Site Public Contact - (morganthaler.jodi@mhsil.com) |
| Chambersburg Hospital Chambersburg, Pennsylvania | Site Public Contact - (ctsucontact@westat.com) |
| Chelsea Hospital Chelsea, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Chester County Hospital West Chester, Pennsylvania | |
| Christiana Care - Union Hospital Elkton, Maryland | Site Public Contact - (frank.crum@christianacare.org) |
| Christiana Care Health System-Christiana Hospital Newark, Delaware | Site Public Contact - (lbarone@christianacare.org) |
| Christiana Care Health System-Concord Health Center Chadds Ford, Pennsylvania | Site Public Contact - (lbarone@christianacare.org) |
| Christiana Care Health System-Wilmington Hospital Wilmington, Delaware | Site Public Contact - (lbarone@christianacare.org) |
| City of Hope Antelope Valley Lancaster, California | |
| City of Hope Comprehensive Cancer Center Duarte, California | |
| City of Hope South Pasadena South Pasadena, California | |
| City of Hope Upland Upland, California | |
| City of Hope at Irvine Lennar Irvine, California | |
| Clackamas Radiation Oncology Center Clackamas, Oregon | Site Public Contact - (CanRsrchStudies@providence.org) |
| Cleveland Clinic Cancer Center Independence Independence, Ohio | |
| Cleveland Clinic Cancer Center Mansfield Mansfield, Ohio | |
| Cleveland Clinic Cancer Center Strongsville Strongsville, Ohio | |
| Cleveland Clinic Cancer Center/Fairview Hospital Cleveland, Ohio | Site Public Contact - (TaussigResearch@ccf.org) |
| Cleveland Clinic Foundation Cleveland, Ohio | Site Public Contact - (TaussigResearch@ccf.org) |
| Cleveland Clinic Mercy Hospital Canton, Ohio | |
| Cleveland Clinic Wooster Family Health and Surgery Center Wooster, Ohio | |
| Cleveland Clinic-Weston Weston, Florida | Site Public Contact - (CancerAnswer@ccf.org) |
| Clinton Memorial Hospital/Foster J Boyd Regional Cancer Center Wilmington, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Colorado Blood Cancer Institute Denver, Colorado | Site Public Contact - (info@westernstatesncorp.org) |
| Columbus Oncology and Hematology Associates Inc Columbus, Ohio | |
| Commonwealth Cancer Center-Corbin Corbin, Kentucky | |
| Community Hospital of Anaconda Anaconda, Montana | Site Public Contact - (mccinfo@mtcancer.org) |
| Community Medical Center Toms River, New Jersey | Site Public Contact - (mccinfo@mtcancer.org) |
| Community Medical Center Toms River, New Jersey | Site Public Contact - (HemonCCTrials@geisinger.edu) |
| Comprehensive Cancer Centers of Nevada Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Comprehensive Cancer Centers of Nevada - Central Valley Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Comprehensive Cancer Centers of Nevada - Henderson Henderson, Nevada | Site Public Contact - (research@sncrf.org) |
| Comprehensive Cancer Centers of Nevada - Northwest Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Comprehensive Cancer Centers of Nevada - Town Center Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Comprehensive Cancer Centers of Nevada-Horizon Ridge Henderson, Nevada | Site Public Contact - (research@sncrf.org) |
| Comprehensive Cancer Centers of Nevada-Southeast Henderson Henderson, Nevada | Site Public Contact - (research@sncrf.org) |
| Comprehensive Cancer Centers of Nevada-Summerlin Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Condell Memorial Hospital Libertyville, Illinois | Site Public Contact - (advocateresearch@advocatehealth.com) |
| Cone Health Cancer Center Greensboro, North Carolina | Site Public Contact - (stacey.phelps@conehealth.com) |
| Cone Health Cancer Center at Alamance Regional Burlington, North Carolina | Site Public Contact - (stacey.phelps@conehealth.com) |
| Cone Health Cancer Center at Asheboro Asheboro, North Carolina | |
| Cone Health Cancer Center at Drawbridge Parkway Greensboro, North Carolina | Site Public Contact - (stacey.phelps@conehealth.com) |
| Cone Heath Cancer Center at Mebane Mebane, North Carolina | |
| Contra Costa Regional Medical Center Martinez, California | |
| Cookeville Regional Medical Center Cookeville, Tennessee | |
| Corewell Health Grand Rapids Hospitals - Butterworth Hospital Grand Rapids, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
| Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital Grand Rapids, Michigan | |
| Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center Saint Joseph, Michigan | |
| Corewell Health Lakeland Hospitals - Niles Hospital Niles, Michigan | |
| Corewell Health Lakeland Hospitals - Saint Joseph Hospital Saint Joseph, Michigan | |
| Corewell Health Reed City Hospital Reed City, Michigan | |
| Cotton O'Neil Cancer Center / Stormont Vail Health Topeka, Kansas | |
| Covenant Medical Center-Lakeside Lubbock, Texas | Site Public Contact - (jaccresearch@covhs.org) |
| CoxHealth South Hospital Springfield, Missouri | |
| Crossroads Cancer Center Effingham, Illinois | Site Public Contact - (morganthaler.jodi@mhsil.com) |
| Dartmouth Cancer Center - Manchester Manchester, New Hampshire | Site Public Contact - (cancer.research.nurse@hitchcock.org) |
| Dartmouth Cancer Center - Nashua Nashua, New Hampshire | Site Public Contact - (cancer.research.nurse@hitchcock.org) |
| Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center Lebanon, New Hampshire | Site Public Contact - (cancer.research.nurse@dartmouth.edu) |
| Dayton Physician LLC - Englewood Dayton, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Dayton Physicians LLC - Troy Troy, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Dayton Physicians LLC-Atrium Franklin, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Dayton Physicians LLC-Miami Valley South Centerville, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Dayton Physicians LLC-Wayne Greenville, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Decatur Memorial Hospital Decatur, Illinois | Site Public Contact - (morganthaler.jodi@mhsil.com) |
| Delaware Clinical and Laboratory Physicians PA Newark, Delaware | |
| Delaware Health Center-Grady Cancer Center Delaware, Ohio | |
| Divine Providence Hospital Williamsport, Pennsylvania | |
| Doctors Hospital Columbus, Ohio | |
| Dublin Methodist Hospital Dublin, Ohio | |
| Duke Raleigh Hospital Raleigh, North Carolina | |
| Duke University Medical Center Durham, North Carolina | |
| Duluth Clinic Ashland Ashland, Wisconsin | Site Public Contact - (CancerTrials@EssentiaHealth.org) |
| Durham VA Medical Center Durham, North Carolina | Site Public Contact - (VHADURcancertrials@va.gov) |
| Eastern Maine Medical Center Bangor, Maine | |
| Eden Hospital Medical Center Castro Valley, California | Site Public Contact - (clinicalresearch@sutterhealth.org) |
| Edward Hines Jr VA Hospital Hines, Illinois | |
| Edwards Comprehensive Cancer Center Huntington, West Virginia | Site Public Contact - (Christina.Cole@chhi.org) |
| Eisenhower Medical Center Rancho Mirage, California | |
| Emory Johns Creek Hospital Johns Creek, Georgia | |
| Emory Saint Joseph's Hospital Atlanta, Georgia | |
| Emory University Hospital Midtown Atlanta, Georgia | |
| Emory University Hospital/Winship Cancer Institute Atlanta, Georgia | |
| Enloe Medical Center Chico, California | |
| Ephrata Cancer Center Ephrata, Pennsylvania | |
| Ephrata Community Hospital Ephrata, Pennsylvania | Site Public Contact - (ctsucontact@westat.com) |
| Essentia Health - Baxter Clinic Baxter, Minnesota | |
| Essentia Health - Deer River Clinic Deer River, Minnesota | Site Public Contact - (CancerTrials@EssentiaHealth.org) |
| Essentia Health - Ely Clinic Ely, Minnesota | |
| Essentia Health - Fosston Fosston, Minnesota | Site Public Contact - (CancerTrials@EssentiaHealth.org) |
| Essentia Health - International Falls Clinic International Falls, Minnesota | |
| Essentia Health - Jamestown Clinic Jamestown, North Dakota | Site Public Contact - (CancerTrials@EssentiaHealth.org) |
| Essentia Health - Moose Lake Clinic Moose Lake, Minnesota | |
| Essentia Health - Park Rapids Park Rapids, Minnesota | Site Public Contact - (CancerTrials@EssentiaHealth.org) |
| Essentia Health Cancer Center Duluth, Minnesota | Site Public Contact - (CancerTrials@EssentiaHealth.org) |
| Essentia Health Cancer Center-South University Clinic Fargo, North Dakota | Site Public Contact - (CancerTrials@EssentiaHealth.org) |
| Essentia Health Hibbing Clinic Hibbing, Minnesota | |
| Essentia Health Saint Joseph's Medical Center Brainerd, Minnesota | Site Public Contact - (CancerTrials@EssentiaHealth.org) |
| Essentia Health Saint Mary's - Detroit Lakes Clinic Detroit Lakes, Minnesota | Site Public Contact - (CancerTrials@EssentiaHealth.org) |
| Essentia Health Saint Mary's Hospital - Superior Superior, Wisconsin | |
| Essentia Health Saint Mary's Medical Center Duluth, Minnesota | Site Public Contact - (CancerTrials@EssentiaHealth.org) |
| Essentia Health Sandstone Sandstone, Minnesota | Site Public Contact - (CancerTrials@EssentiaHealth.org) |
| Essentia Health Virginia Clinic Virginia, Minnesota | Site Public Contact - (CancerTrials@EssentiaHealth.org) |
| Essentia Health-Hayward Clinic Hayward, Wisconsin | Site Public Contact - (CancerTrials@EssentiaHealth.org) |
| Essentia Health-Spooner Clinic Spooner, Wisconsin | Site Public Contact - (CancerTrials@EssentiaHealth.org) |
| FHCC at EvergreenHealth Kirkland, Washington | |
| FHCC at Northwest Hospital Seattle, Washington | |
| Fairbanks Memorial Hospital Fairbanks, Alaska | Site Public Contact - (Veronica.Stevenson@foundationhealth.org) |
| Fairfield Medical Center Lancaster, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Fairview Clinics and Surgery Center Maple Grove Maple Grove, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Fairview Lakes Medical Center Wyoming, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Fairview Northland Medical Center Princeton, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Fairview Ridges Hospital Burnsville, Minnesota | |
| Fairview Southdale Hospital Edina, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Faith Regional Health Services Carson Cancer Center Norfolk, Nebraska | |
| FirstHealth of the Carolinas-Moore Regional Hospital Pinehurst, North Carolina | Site Public Contact - (jcwilliams@firsthealth.org) |
| Flaget Memorial Hospital Bardstown, Kentucky | |
| Fox Chase Cancer Center Philadelphia, Pennsylvania | |
| Fox Chase Cancer Center - East Norriton Hospital Outpatient Center East Norriton, Pennsylvania | Site Public Contact - (ctsucontact@westat.com) |
| Franciscan Health Indianapolis Indianapolis, Indiana | |
| Franciscan Health Mooresville Mooresville, Indiana | |
| Fred Hutchinson Cancer Center Seattle, Washington | |
| Freeman Physician Group of Pittsburg Pittsburg, Kansas | Site Public Contact - (BNMathew@freemanhealth.com) |
| Fremont - Rideout Cancer Center Marysville, California | |
| Fresno Cancer Center Fresno, California | Site Public Contact - (Kpoct@kp.org) |
| Froedtert Menomonee Falls Hospital Menomonee Falls, Wisconsin | |
| Froedtert West Bend Hospital/Kraemer Cancer Center West Bend, Wisconsin | |
| Geauga Hospital Chardon, Ohio | |
| Geisinger Medical Center Danville, Pennsylvania | Site Public Contact - (HemonCCTrials@geisinger.edu) |
| Geisinger Medical Oncology-Lewisburg Lewisburg, Pennsylvania | Site Public Contact - (HemonCCTrials@geisinger.edu) |
| Geisinger Wyoming Valley/Henry Cancer Center Wilkes-Barre, Pennsylvania | Site Public Contact - (HemonCCTrials@geisinger.edu) |
| Gene Upshaw Memorial Tahoe Forest Cancer Center Truckee, California | |
| Genesee Hematology Oncology PC Flint, Michigan | Site Public Contact - (wstrong@ghci.org) |
| Genesis Cancer Center - Silvis Silvis, Illinois | |
| Genesis Healthcare System Cancer Care Center Zanesville, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Genesis Medical Center - East Campus Davenport, Iowa | |
| GenesisCare USA - Fort Apache Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| GenesisCare USA - Henderson Henderson, Nevada | Site Public Contact - (research@sncrf.org) |
| GenesisCare USA - Las Vegas Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| GenesisCare USA - Vegas Tenaya Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Genesys Hurley Cancer Institute Flint, Michigan | Site Public Contact - (wstrong@ghci.org) |
| Gibbs Cancer Center-Gaffney Gaffney, South Carolina | |
| Gibbs Cancer Center-Pelham Greer, South Carolina | |
| Glens Falls Hospital Glens Falls, New York | |
| Good Samaritan Hospital - Cincinnati Cincinnati, Ohio | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Good Samaritan University Hospital West Islip, New York | |
| Goshen Center for Cancer Care Goshen, Indiana | |
| Grady Health System Atlanta, Georgia | |
| Grady Memorial Hospital Atlanta, Georgia | |
| Grant Medical Center Columbus, Ohio | |
| Great Falls Clinic Great Falls, Montana | Site Public Contact - (mccinfo@mtcancer.org) |
| Great Plains Health Callahan Cancer Center North Platte, Nebraska | |
| Greater Baltimore Medical Center Baltimore, Maryland | |
| Greater Dayton Cancer Center Kettering, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Greater Regional Medical Center Creston, Iowa | Site Public Contact - (cancerresearch@mercydesmoines.org) |
| Gulfport Memorial Hospital Gulfport, Mississippi | Site Public Contact - (emede1@lsuhsc.edu) |
| Gundersen Lutheran Medical Center La Crosse, Wisconsin | Site Public Contact - (cancerctr@gundersenhealth.org) |
| Guthrie Medical Group PC-Robert Packer Hospital Sayre, Pennsylvania | |
| HSHS Saint Elizabeth's Hospital O'Fallon, Illinois | Site Public Contact - (morganthaler.jodi@mhsil.com) |
| Harold Alfond Center for Cancer Care Augusta, Maine | |
| Harrison HealthPartners Hematology and Oncology-Poulsbo Poulsbo, Washington | |
| Hartford Hospital Hartford, Connecticut | |
| Hawaii Cancer Care - Westridge ‘Aiea, Hawaii | Site Public Contact - (info@hawaiicancercare.com) |
| Hawaii Cancer Care Inc - Waterfront Plaza Honolulu, Hawaii | Site Public Contact - (i.webster@hawaiicancercare.com) |
| Hawaii Cancer Care Inc-Liliha Honolulu, Hawaii | |
| Hawaii Diagnostic Radiology Services LLC Honolulu, Hawaii | Site Public Contact - (mmiyoshi@hawaiidrs.com) |
| HaysMed Hays, Kansas | |
| Health Partners Inc Minneapolis, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills Las Vegas, Nevada | |
| HealthCare Partners Medical Group Oncology/Hematology-San Martin Las Vegas, Nevada | |
| HealthCare Partners Medical Group Oncology/Hematology-Tenaya Las Vegas, Nevada | |
| Heartland Oncology and Hematology LLP Council Bluffs, Iowa | |
| Heartland Regional Medical Center Saint Joseph, Missouri | |
| Helen F Graham Cancer Center Newark, Delaware | Site Public Contact - (lbarone@christianacare.org) |
| Hematology Oncology Consultants Limited-Darien Darien, Illinois | |
| Hematology Oncology Consultants-Clarkston Clarkston, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Hendrick Medical Center Abilene, Texas | |
| Hennepin County Medical Center Minneapolis, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Henry Ford Cancer Institute-Downriver Brownstown, Michigan | Site Public Contact - (CTOResearch@hfhs.org) |
| Henry Ford Health Providence Novi Hospital Novi, Michigan | |
| Henry Ford Health Providence Southfield Hospital Southfield, Michigan | |
| Henry Ford Health Saint John Hospital Detroit, Michigan | Site Public Contact - (Kkeenan1@hfhs.org) |
| Henry Ford Health Warren Hospital Warren, Michigan | Site Public Contact - (kforman1@hfhs.org) |
| Henry Ford Hematology Oncology - Hayes Clinton Township, Michigan | Site Public Contact - (tpearce1@hfhs.org) |
| Henry Ford Hospital Detroit, Michigan | Site Public Contact - (CTOResearch@hfhs.org) |
| Henry Ford Macomb Health Center - Shelby Township Shelby, Michigan | |
| Henry Ford Macomb Hospital-Clinton Township Clinton Township, Michigan | Site Public Contact - (CTOResearch@hfhs.org) |
| Henry Ford Madison Heights Hospital - Breast Warren, Michigan | Site Public Contact - (kforman1@hfhs.org) |
| Henry Ford Medical Center-Columbus Novi, Michigan | Site Public Contact - (CTOResearch@hfhs.org) |
| Henry Ford Medical Center-Fairlane Dearborn, Michigan | Site Public Contact - (CTOResearch@hfhs.org) |
| Henry Ford River District Hospital East China Township, Michigan | Site Public Contact - (kforman1@hfhs.org) |
| Henry Ford Rochester Hospital Rochester Hills, Michigan | |
| Henry Ford Saint John Hospital - Academic Grosse Pointe Woods, Michigan | Site Public Contact - (kforman1@hfhs.org) |
| Henry Ford Saint John Hospital - Breast Grosse Pointe Woods, Michigan | Site Public Contact - (karen.forman@ascension.org) |
| Henry Ford Saint John Hospital - Macomb Medical Macomb, Michigan | Site Public Contact - (kforman1@hfhs.org) |
| Henry Ford Saint John Hospital - Van Elslander Grosse Pointe Woods, Michigan | Site Public Contact - (kforman1@hfhs.org) |
| Henry Ford Warren Hospital - Breast Macomb Macomb, Michigan | Site Public Contact - (kforman1@hfhs.org) |
| Henry Ford Warren Hospital - GLCMS Warren, Michigan | Site Public Contact - (kforman1@hfhs.org) |
| Henry Ford West Bloomfield Hospital West Bloomfield, Michigan | Site Public Contact - (CTOResearch@hfhs.org) |
| Hi-Line Sletten Cancer Center Havre, Montana | Site Public Contact - (protocols@swog.org) |
| Hillcrest Hospital Cancer Center Mayfield Heights, Ohio | Site Public Contact - (TaussigResearch@ccf.org) |
| Holy Cross Hospital Fort Lauderdale, Florida | Site Public Contact - (eileen.georgi@holy-cross.com) |
| Holy Cross Hospital Fort Lauderdale, Florida | |
| Holy Family Memorial Hospital Manitowoc, Wisconsin | |
| Holy Name Hospital Teaneck, New Jersey | |
| Hope Cancer Care of Nevada Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Hope Cancer Care of Nevada-Pahrump Pahrump, Nevada | Site Public Contact - (research@sncrf.org) |
| Hope Cancer Center Pontiac, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Hope Cancer Clinic Livonia, Michigan | |
| Hunter Holmes McGuire Veterans Administration Medical Center Richmond, Virginia | Site Public Contact - (Regina.McClung@va.gov) |
| Huntsman Cancer Institute/University of Utah Salt Lake City, Utah | Site Public Contact - (cancerinfo@hci.utah.edu) |
| Hurley Medical Center Flint, Michigan | Site Public Contact - (wstrong@ghci.org) |
| Huron Gastroenterology PC Ypsilanti, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| IRMC Cancer Center Indiana, Pennsylvania | |
| Idaho Urologic Institute-Meridian Meridian, Idaho | Site Public Contact - (stephanie.couch@stjoeshealth.org) |
| Illinois CancerCare - Washington Washington, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Bloomington Bloomington, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Canton Canton, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Carthage Carthage, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Dixon Dixon, Illinois | |
| Illinois CancerCare-Eureka Eureka, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Galesburg Galesburg, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Kewanee Clinic Kewanee, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Macomb Macomb, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Ottawa Clinic Ottawa, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Pekin Pekin, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Peoria Peoria, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Peru Peru, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Princeton Princeton, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Indiana University/Melvin and Bren Simon Cancer Center Indianapolis, Indiana | Site Public Contact - (iutrials@iu.edu) |
| Indu and Raj Soin Medical Center Beavercreek, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Ingalls Memorial Hospital Harvey, Illinois | Site Public Contact - (clinicaltrials@ingalls.org) |
| Iowa Cancer Specialists Davenport, Iowa | |
| Iowa City VA Healthcare System Iowa City, Iowa | |
| Iowa Methodist Medical Center Des Moines, Iowa | |
| Island Urology Honolulu, Hawaii | |
| James J Peters VA Medical Center The Bronx, New York | Site Public Contact - (kl2965@cumc.columbia.edu) |
| Jefferson Healthcare Port Townsend, Washington | |
| Jersey Shore Medical Center Neptune City, New Jersey | |
| Jewish Hospital Louisville, Kentucky | |
| Jewish Hospital Medical Center South Shepherdsville, Kentucky | |
| John H Stroger Jr Hospital of Cook County Chicago, Illinois | |
| Kadlec Clinic Hematology and Oncology Kennewick, Washington | Site Public Contact - (research@kadlecmed.org) |
| Kaiser Permanente - Kensington Medical Center Kensington, Maryland | Site Public Contact - (Charmaine.A.Mckie@kp.org) |
| Kaiser Permanente - Largo Medical Center Largo, Maryland | Site Public Contact - (Charmaine.A.Mckie@kp.org) |
| Kaiser Permanente - Panorama City Panorama City, California | Site Public Contact - (clinical.trials@kp.org) |
| Kaiser Permanente Cancer Treatment Center South San Francisco, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente Downtown Commons Sacramento, California | Site Public Contact - (kpoct@kp.org) |
| Kaiser Permanente Dublin Dublin, California | |
| Kaiser Permanente Los Angeles Medical Center Los Angeles, California | Site Public Contact - (clinical.trials@kp.org) |
| Kaiser Permanente Lutherville - Timonium Medical Center Lutherville, Maryland | Site Public Contact - (Charmaine.A.Mckie@kp.org) |
| Kaiser Permanente Medical Center - Santa Clara Santa Clara, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente Medical Center-Vacaville Vacaville, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente Moanalua Medical Center Honolulu, Hawaii | Site Public Contact - (shelley.a.clark@kp.org) |
| Kaiser Permanente Northwest Portland, Oregon | |
| Kaiser Permanente Oakland-Broadway Oakland, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente Sacramento Medical Center Sacramento, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente San Leandro San Leandro, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente South Bay Harbor City, California | Site Public Contact - (clinical.trials@kp.org) |
| Kaiser Permanente Tysons Corner Medical Center McLean, Virginia | Site Public Contact - (Charmaine.A.Mckie@kp.org) |
| Kaiser Permanente West Los Angeles Los Angeles, California | Site Public Contact - (clinical.trials@kp.org) |
| Kaiser Permanente-Anaheim Anaheim, California | Site Public Contact - (clinical.trials@kp.org) |
| Kaiser Permanente-Baldwin Park Baldwin Park, California | Site Public Contact - (clinical.trials@kp.org) |
| Kaiser Permanente-Bellflower Bellflower, California | Site Public Contact - (clinical.trials@kp.org) |
| Kaiser Permanente-Burke Medical Center Burke, Virginia | Site Public Contact - (Charmaine.A.Mckie@kp.org) |
| Kaiser Permanente-Capitol Hill Medical Center Washington D.C., District of Columbia | Site Public Contact - (Charmaine.A.Mckie@kp.org) |
| Kaiser Permanente-Caton Hill Medical Center Woodbridge, Virginia | Site Public Contact - (Charmaine.A.Mckie@kp.org) |
| Kaiser Permanente-Deer Valley Medical Center Antioch, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-Fontana Fontana, California | Site Public Contact - (clinical.trials@kp.org) |
| Kaiser Permanente-Franklin Denver, Colorado | |
| Kaiser Permanente-Fremont Fremont, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-Fresno Fresno, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-Gaithersburg Medical Center Gaithersburg, Maryland | Site Public Contact - (Charmaine.A.Mckie@kp.org) |
| Kaiser Permanente-Irvine Irvine, California | Site Public Contact - (clinical.trials@kp.org) |
| Kaiser Permanente-Modesto Modesto, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-Oakland Oakland, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-Ontario Ontario, California | Site Public Contact - (clinical.trials@kp.org) |
| Kaiser Permanente-Rancho Cordova Cancer Center Rancho Cordova, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-Redwood City Redwood City, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-Richmond Richmond, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-Riverside Riverside, California | Site Public Contact - (clinical.trials@kp.org) |
| Kaiser Permanente-Roseville Roseville, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-San Diego Mission San Diego, California | Site Public Contact - (clinical.trials@kp.org) |
| Kaiser Permanente-San Diego Zion San Diego, California | Site Public Contact - (clinical.trials@kp.org) |
| Kaiser Permanente-San Francisco San Francisco, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-San Marcos San Marcos, California | Site Public Contact - (clinical.trials@kp.org) |
| Kaiser Permanente-San Rafael San Rafael, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-Santa Rosa Santa Rosa, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-Santa Teresa-San Jose San Jose, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-South Sacramento Sacramento, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-South San Francisco South San Francisco, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-Stockton Stockton, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-Vallejo Vallejo, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-Walnut Creek Walnut Creek, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-Woodland Hills Woodland Hills, California | Site Public Contact - (clinical.trials@kp.org) |
| Kaiser Permanente-Woodlawn Medical Center Baltimore, Maryland | Site Public Contact - (Charmaine.A.Mckie@kp.org) |
| Kaiser San Rafael-Gallinas San Rafael, California | Site Public Contact - (Kpoct@kp.org) |
| Kansas City Veterans Affairs Medical Center Kansas City, Missouri | |
| Kapiolani Medical Center for Women and Children Honolulu, Hawaii | |
| Katmai Oncology Group Anchorage, Alaska | Site Public Contact - (AKPAMC.OncologyResearchSupport@providence.org) |
| Kettering Medical Center Kettering, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| King's Daughter's Medical Center Ashland, Kentucky | |
| Kingman Regional Medical Center Kingman, Arizona | Site Public Contact - (research@sncrf.org) |
| Knox Community Hospital Mount Vernon, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Kootenai Clinic Cancer Services - Post Falls Post Falls, Idaho | Site Public Contact - (mccinfo@mtcancer.org) |
| Kootenai Clinic Cancer Services - Sandpoint Sandpoint, Idaho | Site Public Contact - (mccinfo@mtcancer.org) |
| Kootenai Health - Coeur d'Alene Coeur d'Alene, Idaho | Site Public Contact - (mccinfo@mtcancer.org) |
| Kuakini Medical Center Honolulu, Hawaii | |
| LSU Health Baton Rouge-North Clinic Baton Rouge, Louisiana | Site Public Contact - (research@ololrmc.com) |
| Lafayette Family Cancer Center-EMMC Brewer, Maine | |
| Lahey Hospital and Medical Center Burlington, Massachusetts | Site Public Contact - (lhmc-cancer-clinical-trials@lahey.org) |
| Lahey Medical Center-Peabody Peabody, Massachusetts | Site Public Contact - (lhmc-cancer-clinical-trials@lahey.org) |
| Lake Region Healthcare Corporation-Cancer Care Fergus Falls, Minnesota | |
| Lakeview Hospital Stillwater, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Langlade Hospital and Cancer Center Antigo, Wisconsin | Site Public Contact - (Juli.Alford@aspirus.org) |
| Lankenau Medical Center Wynnewood, Pennsylvania | Site Public Contact - (turzoe@mlhs.org) |
| Las Vegas Cancer Center-Henderson Henderson, Nevada | |
| Las Vegas Cancer Center-Medical Center Las Vegas, Nevada | |
| Las Vegas Prostate Cancer Center Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Las Vegas Urology - Cathedral Rock Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Las Vegas Urology - Green Valley Henderson, Nevada | Site Public Contact - (research@sncrf.org) |
| Las Vegas Urology - Pebble Henderson, Nevada | Site Public Contact - (research@sncrf.org) |
| Las Vegas Urology - Pecos Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Las Vegas Urology - Smoke Ranch Las Vegas, Nevada | Site Public Contact - (research@smcrf.org) |
| Las Vegas Urology - Sunset Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Lawrence Memorial Hospital Lawrence, Kansas | Site Public Contact - (Stephanie.Norris@LMH.ORG) |
| Lehigh Valley Hospital - Muhlenberg Bethlehem, Pennsylvania | Site Public Contact - (Morgan_M.Horton@lvhn.org) |
| Lehigh Valley Hospital-Cedar Crest Allentown, Pennsylvania | Site Public Contact - (Morgan_M.Horton@lvhn.org) |
| Lehigh Valley Hospital-Hazleton Hazleton, Pennsylvania | Site Public Contact - (Morgan_M.Horton@lvhn.org) |
| Lewis Cancer and Research Pavilion at Saint Joseph's/Candler Savannah, Georgia | Site Public Contact - (underberga@sjchs.org) |
| Licking Memorial Hospital Newark, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Littleton Adventist Hospital Littleton, Colorado | |
| Logan Health Medical Center Kalispell, Montana | Site Public Contact - (mccinfo@mtcancer.org) |
| Logan Regional Hospital Logan, Utah | |
| Loma Linda University Medical Center Loma Linda, California | |
| Longmont United Hospital Longmont, Colorado | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Louis Stokes Cleveland VA Medical Center Cleveland, Ohio | Site Public Contact - (holly.henry@va.gov) |
| Louisiana Hematology Oncology Associates LLC Baton Rouge, Louisiana | Site Public Contact - (clinicalresearch@marybird.com) |
| Louisiana State University Health Science Center New Orleans, Louisiana | Site Public Contact - (emede1@lsuhsc.edu) |
| Lovelace Medical Center-Saint Joseph Square Albuquerque, New Mexico | |
| Lowell General Hospital Lowell, Massachusetts | Site Public Contact - (ghincks@lowellgeneral.org) |
| Loyola Center for Health at Burr Ridge Burr Ridge, Illinois | |
| Loyola Medicine Homer Glen Homer Glen, Illinois | |
| Loyola University Medical Center Maywood, Illinois | |
| Luminis Health Anne Arundel Medical Center Annapolis, Maryland | Site Public Contact - (research@luminishealth.org) |
| M D Anderson Cancer Center Houston, Texas | Site Public Contact - (askmdanderson@mdanderson.org) |
| MGC Hematology Oncology-Union Union, South Carolina | |
| Main Line Health Center-Collegeville Collegeville, Pennsylvania | |
| Main Line Health Center-Exton Exton, Pennsylvania | |
| Maine Medical Partners - South Portland South Portland, Maine | Site Public Contact - (ClinicalResearch@mmc.org) |
| MaineHealth/SMHC Cancer Care and Blood Disorders-Biddeford Biddeford, Maine | Site Public Contact - (LLemire@mmc.org) |
| MaineHealth/SMHC Cancer Care and Blood Disorders-Sanford Sanford, Maine | Site Public Contact - (LLemire@mmc.org) |
| Malcom Randall Veterans Administration Medical Center Gainesville, Florida | Site Public Contact - (trials@cancer.ufl.edu) |
| Margaret R Pardee Memorial Hospital Hendersonville, North Carolina | |
| Marietta Memorial Hospital Marietta, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Marjorie Weinberg Cancer Center at Loyola-Gottlieb Melrose Park, Illinois | |
| Marshall Cancer Center Cameron Park, California | Site Public Contact - (cancerservices@marshallmedical.org) |
| Marshfield Clinic - Wisconsin Rapids Center Wisconsin Rapids, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Clinic-Chippewa Center Chippewa Falls, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Clinic-Wausau Center Wausau, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center - Ladysmith Ladysmith, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center - Minocqua Minocqua, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center - Weston Weston, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center-EC Cancer Center Eau Claire, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center-Marshfield Marshfield, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center-Rice Lake Rice Lake, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center-River Region at Stevens Point Stevens Point, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Mary Bird Perkins Cancer Center Baton Rouge, Louisiana | Site Public Contact - (clinicalresearch@marybird.com) |
| Mary Greeley Medical Center Ames, Iowa | |
| Mary Imogene Bassett Hospital Cooperstown, New York | |
| McFarland Clinic - Ames Ames, Iowa | Site Public Contact - (ksoder@mcfarlandclinic.com) |
| McFarland Clinic - Boone Boone, Iowa | |
| McFarland Clinic - Jefferson Jefferson, Iowa | |
| McFarland Clinic - Marshalltown Marshalltown, Iowa | |
| McFarland Clinic - Trinity Cancer Center Fort Dodge, Iowa | |
| Medical Center of Baton Rouge Baton Rouge, Louisiana | |
| Medical Center of the Rockies Loveland, Colorado | |
| Medical College of Wisconsin Milwaukee, Wisconsin | |
| Medical Oncology Hematology Consultants PA Newark, Delaware | Site Public Contact - (lbarone@christianacare.org) |
| Medical University of South Carolina Charleston, South Carolina | |
| Memorial Hospital Marysville, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Memorial Hospital East Shiloh, Illinois | Site Public Contact - (dschwab@wustl.edu) |
| Memorial Hospital North Colorado Springs, Colorado | |
| Memorial Hospital West Pembroke Pines, Florida | |
| Memorial Hospital of South Bend South Bend, Indiana | |
| Memorial Medical Center Modesto, California | Site Public Contact - (clinicalresearch@sutterhealth.org) |
| Memorial Medical Center - Las Cruces Las Cruces, New Mexico | |
| Memorial Regional Hospital/Joe DiMaggio Children's Hospital Hollywood, Florida | Site Public Contact - (OHR@mhs.net) |
| Memorial Sloan Kettering Basking Ridge Basking Ridge, New Jersey | |
| Memorial Sloan Kettering Bergen Montvale, New Jersey | |
| Memorial Sloan Kettering Cancer Center New York, New York | |
| Memorial Sloan Kettering Commack Commack, New York | |
| Memorial Sloan Kettering Monmouth Middletown, New Jersey | |
| Memorial Sloan Kettering Nassau Uniondale, New York | |
| Memorial Sloan Kettering Westchester Harrison, New York | |
| Mercy Cancer Center - Carmichael Carmichael, California | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Mercy Cancer Center - Elk Grove Elk Grove, California | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Mercy Cancer Center - Rocklin Rocklin, California | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Mercy Cancer Center - Sacramento Sacramento, California | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Mercy Cancer Center-West Lakes Clive, Iowa | Site Public Contact - (cancerresearch@mercydesmoines.org) |
| Mercy Health - Paducah Cancer Center Paducah, Kentucky | Site Public Contact - (BJWarner@mercy.com) |
| Mercy Health - Perrysburg Hospital Perrysburg, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Mercy Health - Saint Anne Hospital Toledo, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Mercy Health - Saint Vincent Hospital Toledo, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Mercy Health Sylvania Radiation Oncology Center Toledo, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Mercy Hematology and Oncology Associates Inc Canton, Ohio | |
| Mercy Hospital Coon Rapids, Minnesota | |
| Mercy Hospital Coon Rapids, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Mercy Hospital Joplin Joplin, Missouri | |
| Mercy Hospital Oklahoma City Oklahoma City, Oklahoma | |
| Mercy Hospital Saint Louis St Louis, Missouri | |
| Mercy Hospital South St Louis, Missouri | Site Public Contact - (Danielle.Werle@mercy.net) |
| Mercy Hospital Springfield Springfield, Missouri | |
| Mercy Medical Center Durango, Colorado | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Mercy Medical Center - Des Moines Des Moines, Iowa | Site Public Contact - (cancerresearch@mercydesmoines.org) |
| Mercy Medical Center-West Lakes West Des Moines, Iowa | Site Public Contact - (cancerresearch@mercydesmoines.org) |
| Mercy San Juan Medical Center Carmichael, California | Site Public Contact - (OncologyResearch@DignityHealth.org) |
| MercyOne Genesis Davenport Cancer Center Davenport, Iowa | |
| Mercyhealth Hospital and Cancer Center - Janesville Janesville, Wisconsin | Site Public Contact - (oncologyclinicaltrials@mhemail.org) |
| Mercyhealth Javon Bea Hospital - Rockton Rockford, Illinois | Site Public Contact - (oncologyclinicaltrials@mhemail.org) |
| Methodist Jennie Edmundson Hospital Council Bluffs, Iowa | Site Public Contact - (kathryn.bartz@nmhs.org) |
| Methodist Medical Center of Illinois Peoria, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| MetroHealth Medical Center Cleveland, Ohio | Site Public Contact - (ababal@metrohealth.org) |
| Miami Valley Cancer Care and Infusion Greenville, Ohio | |
| Miami Valley Hospital Dayton, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Miami Valley Hospital North Dayton, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Miami Valley Hospital South Centerville, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Michigan Healthcare Professionals Pontiac Pontiac, Michigan | Site Public Contact - (Emily.Crofts@trinity-health.org) |
| Midstate Medical Center Meriden, Connecticut | |
| Midwestern Regional Medical Center Zion, Illinois | |
| Miller-Dwan Hospital Duluth, Minnesota | Site Public Contact - (CancerTrials@EssentiaHealth.org) |
| Mills Health Center San Mateo, California | Site Public Contact - (clinicalresearch@sutterhealth.org) |
| Mills-Peninsula Medical Center Burlingame, California | Site Public Contact - (clinicalresearch@sutterhealth.org) |
| Minneapolis VA Medical Center Minneapolis, Minnesota | |
| Minnesota Oncology - Burnsville Burnsville, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Minnesota Oncology Hematology PA-Maplewood Maplewood, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Minnesota Oncology Hematology PA-Woodbury Woodbury, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Mission Cancer and Blood - Ankeny Ankeny, Iowa | |
| Mission Cancer and Blood - Des Moines Des Moines, Iowa | |
| Mission Cancer and Blood - Laurel Des Moines, Iowa | |
| Mission Cancer and Blood - West Des Moines Clive, Iowa | |
| Mission Hospital Asheville, North Carolina | |
| Missouri Baptist Medical Center St Louis, Missouri | |
| Missouri Baptist Sullivan Hospital Sullivan, Missouri | |
| Moffitt Cancer Center Tampa, Florida | |
| Monmouth Medical Center Long Branch, New Jersey | Site Public Contact - (mary.danish@rwjbh.org) |
| Monmouth Medical Center Southern Campus Lakewood, New Jersey | Site Public Contact - (mary.danish@rwjbh.org) |
| Montefiore Medical Center - Moses Campus The Bronx, New York | Site Public Contact - (eskwak@montefiore.org) |
| Montefiore Medical Center-Einstein Campus The Bronx, New York | Site Public Contact - (eskwak@montefiore.org) |
| Montefiore Medical Center-Weiler Hospital The Bronx, New York | Site Public Contact - (eskwak@montefiore.org) |
| Monticello Cancer Center Monticello, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Mount Carmel East Hospital Columbus, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Mount Carmel Grove City Hospital Grove City, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Mount Carmel Health Center West Columbus, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Mount Carmel New Albany Surgical Hospital New Albany, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Mount Sinai Chelsea New York, New York | Site Public Contact - (CCTO@mssm.edu) |
| Mount Sinai Comprehensive Cancer Center at Aventura Aventura, Florida | Site Public Contact - (yenrique@msmc.com) |
| Mount Sinai Hospital New York, New York | Site Public Contact - (CCTO@mssm.edu) |
| Mount Sinai Hospital Medical Center Chicago, Illinois | Site Public Contact - (suhi@sinai.org) |
| Mount Sinai Medical Center Miami Beach, Florida | Site Public Contact - (yenrique@msmc.com) |
| Mountain Blue Cancer Care Center - Swedish Englewood, Colorado | |
| MultiCare Auburn Medical Center Auburn, Washington | |
| MultiCare Deaconess Cancer and Blood Specialty Center - Downtown Spokane, Washington | |
| MultiCare Deaconess Cancer and Blood Specialty Center - North Spokane, Washington | |
| MultiCare Deaconess Cancer and Blood Specialty Center - Valley Spokane Valley, Washington | |
| MultiCare Gig Harbor Medical Park Gig Harbor, Washington | |
| MultiCare Good Samaritan Hospital Puyallup, Washington | |
| MultiCare Tacoma General Hospital Tacoma, Washington | |
| Munson Medical Center Traverse City, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
| MyMichigan Medical Center Saginaw Saginaw, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| MyMichigan Medical Center Tawas Tawas City, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro Jonesboro, Arkansas | Site Public Contact - (Emily.Carvell@bmhcc.org) |
| Nebraska Cancer Specialists - Omaha Omaha, Nebraska | |
| Nebraska Cancer Specialists/Oncology Hematology West PC Grand Island, Nebraska | |
| Nebraska Cancer Specialists/Oncology Hematology West PC - MECC Omaha, Nebraska | |
| Nebraska Cancer Specialists/Oncology Hematology West PC - MEJ Council Bluffs, Iowa | Site Public Contact - (Liza.brandes@nmhs.org) |
| Nebraska Hematology and Oncology Lincoln, Nebraska | |
| Nebraska Methodist Hospital Omaha, Nebraska | |
| New Hampshire Oncology Hematology PA-Concord Concord, New Hampshire | |
| New Mexico Oncology Hematology Consultants Albuquerque, New Mexico | |
| New Ulm Medical Center New Ulm, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Newark Beth Israel Medical Center Newark, New Jersey | |
| Newark Radiation Oncology Newark, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Newland Medical Associates-Clarkston Clarkston, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Newland Medical Associates-Pontiac Pontiac, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| North Coast Cancer Care Sandusky, Ohio | Site Public Contact - (TaussigResearch@ccf.org) |
| North Memorial Medical Health Center Robbinsdale, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| North Star Lodge Cancer Center at Yakima Valley Memorial Hospital Yakima, Washington | Site Public Contact - (Memorial-ClinicalTrials@yvmh.org) |
| NorthShore University HealthSystem-Evanston Hospital Evanston, Illinois | |
| NorthShore University HealthSystem-Glenbrook Hospital Glenview, Illinois | |
| NorthShore University HealthSystem-Highland Park Hospital Highland Park, Illinois | |
| Northbay Cancer Center Vacaville, California | |
| Northeast Georgia Medical Center Braselton Braselton, Georgia | Site Public Contact - (cancerpatient.navigator@nghs.com) |
| Northeast Georgia Medical Center-Gainesville Gainesville, Georgia | Site Public Contact - (cancerpatient.navigator@nghs.com) |
| Northshore Oncology Associates-Covington Covington, Louisiana | Site Public Contact - (clinicalresearch@marybird.com) |
| Northside Hospital Atlanta, Georgia | Site Public Contact - (ClinicalTrials@northside.com) |
| Northside Hospital - Duluth Duluth, Georgia | Site Public Contact - (Clinical.trials@northside.com) |
| Northside Hospital - Gwinnett Lawrenceville, Georgia | Site Public Contact - (Clinical.trials@northside.com) |
| Northwest Hospital Center Randallstown, Maryland | Site Public Contact - (cancerinstitute@lifebridgehealth.org) |
| Northwest Wisconsin Cancer Center Ashland, Wisconsin | Site Public Contact - (CancerTrials@EssentiaHealth.org) |
| Northwestern Medicine Cancer Center Delnor Geneva, Illinois | Site Public Contact - (Donald.Smith3@nm.org) |
| Northwestern Medicine Cancer Center Kishwaukee DeKalb, Illinois | Site Public Contact - (Donald.Smith3@nm.org) |
| Northwestern Medicine Cancer Center Warrenville Warrenville, Illinois | Site Public Contact - (Donald.Smith3@nm.org) |
| Northwestern Medicine Glenview Outpatient Center Glenview, Illinois | |
| Northwestern Medicine Grayslake Outpatient Center Grayslake, Illinois | |
| Northwestern Medicine Lake Forest Hospital Lake Forest, Illinois | Site Public Contact - (cancertrials@northwestern.edu) |
| Northwestern Medicine Orland Park Orland Park, Illinois | Site Public Contact - (nctnprogram_rhlccc@northwestern.edu) |
| Northwestern University Chicago, Illinois | Site Public Contact - (cancer@northwestern.edu) |
| Novant Health Cancer Institute - Kernersville Kernersville, North Carolina | |
| Novant Health Cancer Institute - Mount Airy Mount Airy, North Carolina | |
| Novant Health Cancer Institute - Statesville Statesville, North Carolina | |
| Novant Health Cancer Institute - Thomasville Thomasville, North Carolina | |
| Novant Health Cancer Institute - Wilkesboro North Wilkesboro, North Carolina | |
| Novant Health Forsyth Medical Center Winston-Salem, North Carolina | |
| Novant Health Oncology Specialists Winston-Salem, North Carolina | Site Public Contact - (asmarrs@novanthealth.org) |
| Novant Health Presbyterian Medical Center Charlotte, North Carolina | |
| OSF Saint Anthony Medical Center Rockford, Illinois | |
| OSF Saint Anthony's Health Center Alton, Illinois | |
| OSF Saint Francis Hospital and Medical Group Escanaba, Michigan | Site Public Contact - (ewd_research_admin@hshs.org) |
| Ochsner High Grove Baton Rouge, Louisiana | |
| Ochsner Medical Center Jefferson New Orleans, Louisiana | |
| Ochsner Medical Center Kenner Kenner, Louisiana | |
| Ohio State University Comprehensive Cancer Center Columbus, Ohio | |
| OhioHealth Mansfield Hospital Mansfield, Ohio | |
| OhioHealth Marion General Hospital Marion, Ohio | |
| Oklahoma Cancer Specialists and Research Institute-Tulsa Tulsa, Oklahoma | |
| Oncology Associates PC Omaha, Nebraska | Site Public Contact - (info@oa-oc.com) |
| Oncology Associates at Mercy Medical Center Cedar Rapids, Iowa | |
| Oncology Center of The South Incorporated Houma, Louisiana | |
| Oncology Hematology Associates of Saginaw Valley PC Saginaw, Michigan | |
| Oncology Hematology Care Inc-Kenwood Cincinnati, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Oncology Hematology West PC Omaha, Nebraska | |
| OptumCare Cancer Care at Charleston Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| OptumCare Cancer Care at Fort Apache Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| OptumCare Cancer Care at MountainView Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| OptumCare Cancer Care at Seven Hills Henderson, Nevada | Site Public Contact - (research@sncrf.org) |
| Oregon Health and Science University Portland, Oregon | Site Public Contact - (trials@ohsu.edu) |
| Orion Cancer Care Findlay, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Our Lady of The Lake Baton Rouge, Louisiana | |
| Our Lady of the Lake Physician Group Baton Rouge, Louisiana | Site Public Contact - (research@ololrmc.com) |
| Overlake Medical Center Bellevue, Washington | |
| Overton Brooks Veteran's Administration Medical Center Shreveport, Louisiana | |
| Owensboro Health Mitchell Memorial Cancer Center Owensboro, Kentucky | Site Public Contact - (vanissa.sorrels@owensborohealth.org) |
| PCR Oncology Arroyo Grande, California | Site Public Contact - (research@sncrf.org) |
| Pali Momi Medical Center ‘Aiea, Hawaii | |
| Palo Alto Medical Foundation Health Care Palo Alto, California | Site Public Contact - (clinicalresearch@sutterhealth.org) |
| Palo Alto Medical Foundation-Camino Division Mountain View, California | Site Public Contact - (clinicalresearch@sutterhealth.org) |
| Palo Alto Medical Foundation-Fremont Fremont, California | Site Public Contact - (clinicalresearch@sutterhealth.org) |
| Palo Alto Medical Foundation-Gynecologic Oncology Mountain View, California | Site Public Contact - (clinicalresearch@sutterhealth.org) |
| Palo Alto Medical Foundation-Santa Cruz Santa Cruz, California | Site Public Contact - (clinicalresearch@sutterhealth.org) |
| Palo Alto Medical Foundation-Sunnyvale Sunnyvale, California | Site Public Contact - (clinicalresearch@sutterhealth.org) |
| Paoli Memorial Hospital Paoli, Pennsylvania | Site Public Contact - (turzoe@mlhs.org) |
| Park Nicollet Clinic - Saint Louis Park Saint Louis Park, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Parker Adventist Hospital Parker, Colorado | |
| Parkland Health Center - Farmington Farmington, Missouri | |
| Parkland Health Center-Bonne Terre Bonne Terre, Missouri | |
| Parkland Memorial Hospital Dallas, Texas | Site Public Contact - (canceranswerline@UTSouthwestern.edu) |
| Parkview Regional Medical Center Fort Wayne, Indiana | |
| PeaceHealth Saint John Medical Center Longview, Washington | Site Public Contact - (kmakin-bond@peacehealth.org) |
| PeaceHealth Saint Joseph Medical Center Bellingham, Washington | |
| PeaceHealth Southwest Medical Center Vancouver, Washington | Site Public Contact - (kmakin-bond@peacehealth.org) |
| PeaceHealth United General Medical Center Sedro-Woolley, Washington | Site Public Contact - (rcrompton@peacehealth.org) |
| Peninsula Cancer Institute-Cancer Specialists of Tidewater Virginia Beach, Virginia | |
| Peninsula Cancer Institute-Gloucester Gloucester, Virginia | |
| Peninsula Cancer Institute-Newport News Newport News, Virginia | |
| Peninsula Cancer Institute-Williamsburg Williamsburg, Virginia | |
| Penn State Health Saint Joseph Medical Center Reading, Pennsylvania | |
| Penn State Milton S Hershey Medical Center Hershey, Pennsylvania | |
| Penobscot Bay Medical Center Rockport, Maine | Site Public Contact - (ClinicalResearch@mmc.org) |
| Penrose-Saint Francis Healthcare Colorado Springs, Colorado | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Phoebe Putney Memorial Hospital Albany, Georgia | |
| Pocono Medical Center East Stroudsburg, Pennsylvania | Site Public Contact - (Morgan_M.Horton@lvhn.org) |
| Pottstown Hospital Pottstown, Pennsylvania | |
| Poudre Valley Hospital Fort Collins, Colorado | |
| Premier Blood and Cancer Center Dayton, Ohio | |
| Presbyterian - Saint Lukes Medical Center - Health One Denver, Colorado | Site Public Contact - (info@westernstatesncorp.org) |
| Presbyterian Intercommunity Hospital Whittier, California | |
| Presbyterian Kaseman Hospital Albuquerque, New Mexico | Site Public Contact - (WBurman@phs.org) |
| Presbyterian Rust Medical Center/Jorgensen Cancer Center Rio Rancho, New Mexico | Site Public Contact - (WBurman@phs.org) |
| Prisma Health Cancer Institute - Butternut Greenville, South Carolina | |
| Prisma Health Cancer Institute - Easley Easley, South Carolina | Site Public Contact - (Kim.Williams3@prismahealth.org) |
| Prisma Health Cancer Institute - Eastside Greenville, South Carolina | |
| Prisma Health Cancer Institute - Faris Greenville, South Carolina | |
| Prisma Health Cancer Institute - Greer Greer, South Carolina | |
| Prisma Health Cancer Institute - Laurens Clinton, South Carolina | |
| Prisma Health Cancer Institute - Seneca Seneca, South Carolina | |
| Prisma Health Cancer Institute - Spartanburg Boiling Springs, South Carolina | |
| Prisma Health Greenville Memorial Hospital Greenville, South Carolina | |
| ProHealth D N Greenwald Center Mukwonago, Wisconsin | Site Public Contact - (research.institute@phci.org) |
| ProHealth Oconomowoc Memorial Hospital Oconomowoc, Wisconsin | |
| ProHealth Waukesha Memorial Hospital Waukesha, Wisconsin | |
| ProMedica Flower Hospital Sylvania, Ohio | Site Public Contact - (PCIOncResearch@promedica.org) |
| ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital Toledo, Ohio | Site Public Contact - (PCIOncResearch@promedica.org) |
| Providence Alaska Medical Center Anchorage, Alaska | Site Public Contact - (AKPAMC.OncologyResearchSupport@providence.org) |
| Providence Cancer Institute Clackamas Clinic Clackamas, Oregon | |
| Providence Medical Foundation - Santa Rosa Santa Rosa, California | |
| Providence Newberg Medical Center Newberg, Oregon | Site Public Contact - (CanRsrchStudies@providence.org) |
| Providence Portland Medical Center Portland, Oregon | Site Public Contact - (CanRsrchStudies@providence.org) |
| Providence Queen of The Valley Napa, California | |
| Providence Regional Cancer Partnership Everett, Washington | Site Public Contact - (marilyn.birchman@providence.org) |
| Providence Regional Cancer System-Aberdeen Aberdeen, Washington | Site Public Contact - (deidre.dillon@providence.org) |
| Providence Regional Cancer System-Centralia Centralia, Washington | Site Public Contact - (deidre.dillon@providence.org) |
| Providence Regional Cancer System-Lacey Lacey, Washington | Site Public Contact - (deidre.dillon@providence.org) |
| Providence Saint Joseph Medical Center/Disney Family Cancer Center Burbank, California | Site Public Contact - (Najee.Boucher@providence.org) |
| Providence Saint Mary Regional Cancer Center Walla Walla, Washington | Site Public Contact - (Cheryl.Dodd@providence.org) |
| Providence Saint Vincent Medical Center Portland, Oregon | Site Public Contact - (CanRsrchStudies@providence.org) |
| Providence Santa Rosa Memorial Hospital Santa Rosa, California | |
| Providence Veterans Administration Hospital Providence, Rhode Island | |
| Providence Willamette Falls Medical Center Oregon City, Oregon | Site Public Contact - (CanRsrchStudies@providence.org) |
| Queen's Cancer Cenrer - POB I Honolulu, Hawaii | |
| Queen's Cancer Center - Kuakini Honolulu, Hawaii | |
| Queen's Cancer Center - Pearlridge ‘Aiea, Hawaii | |
| Queen's Medical Center Honolulu, Hawaii | |
| Radiation Oncology Associates Reno, Nevada | Site Public Contact - (research@sncrf.org) |
| Radiation Oncology Centers of Nevada Central Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Radiation Oncology Centers of Nevada Southeast Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Ralph H Johnson VA Medical Center Charleston, South Carolina | Site Public Contact - (ashley.salvo@va.gov) |
| Randolph Health Cancer Center Asheboro, North Carolina | Site Public Contact - (stacey.phelps@conehealth.com) |
| Randolph Hospital Asheboro, North Carolina | |
| Rapid City Regional Hospital Rapid City, South Dakota | Site Public Contact - (research@monument.health) |
| Regional West Medical Center Cancer Center Scottsbluff, Nebraska | |
| Regions Hospital Saint Paul, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Reid Health Richmond, Indiana | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Renown Regional Medical Center Reno, Nevada | Site Public Contact - (research@sncrf.org) |
| Rex Hematology Oncology Associates-Blue Ridge Raleigh, North Carolina | |
| Rex Hematology Oncology Associates-Cary Cary, North Carolina | Site Public Contact - (CancCtrOncologyClinicalResearch@unchealth.unc.edu) |
| Rex Hematology Oncology Associates-Garner Garner, North Carolina | Site Public Contact - (CancCtrOncologyClinicalResearch@unchealth.unc.edu) |
| Rice Memorial Hospital Willmar, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Richard L. Roudebush Veterans Affairs Medical Center Indianapolis, Indiana | Site Public Contact - (iutrials@iu.edu) |
| Riddle Memorial Hospital Media, Pennsylvania | Site Public Contact - (turzoe@mlhs.org) |
| Ridgeview Medical Center Waconia, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Ridley-Tree Cancer Center Santa Barbara, California | Site Public Contact - (clinicalresearch@sutterhealth.org) |
| Riverside Methodist Hospital Columbus, Ohio | |
| Riverview Medical Center/Booker Cancer Center Red Bank, New Jersey | |
| Riverwood Healthcare Center Aitkin, Minnesota | Site Public Contact - (CancerTrials@EssentiaHealth.org) |
| Robert Wood Johnson University Hospital Somerset Somerville, New Jersey | |
| Rocky Mountain Cancer Centers - Centennial Centennial, Colorado | Site Public Contact - (info@westernstatesncorp.org) |
| Rocky Mountain Cancer Centers - Swedish Englewood, Colorado | Site Public Contact - (info@westernstatesncorp.org) |
| Rocky Mountain Cancer Centers-Aurora Aurora, Colorado | Site Public Contact - (info@westernstatesncorp.org) |
| Rocky Mountain Cancer Centers-Boulder Boulder, Colorado | Site Public Contact - (info@westernstatesncorp.org) |
| Rocky Mountain Cancer Centers-Lakewood Lakewood, Colorado | Site Public Contact - (info@westernstatesncorp.org) |
| Rocky Mountain Cancer Centers-Littleton Littleton, Colorado | Site Public Contact - (info@westernstatesncorp.org) |
| Rocky Mountain Cancer Centers-Longmont Longmont, Colorado | Site Public Contact - (ResearchTracking@Centura.Org) |
| Rocky Mountain Cancer Centers-Midtown Denver, Colorado | Site Public Contact - (info@westernstatesncorp.org) |
| Rocky Mountain Cancer Centers-Penrose Colorado Springs, Colorado | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Rocky Mountain Cancer Centers-Rose Denver, Colorado | Site Public Contact - (info@westernstatesncorp.org) |
| Rocky Mountain Cancer Centers-Sky Ridge Lone Tree, Colorado | Site Public Contact - (info@westernstatesncorp.org) |
| Rocky Mountain Cancer Centers-Thornton Thornton, Colorado | Site Public Contact - (info@westernstatesncorp.org) |
| Rocky Mountain Regional VA Medical Center Aurora, Colorado | |
| Rohnert Park Cancer Center Rohnert Park, California | Site Public Contact - (Kpoct@kp.org) |
| Rose Medical Center Denver, Colorado | |
| Roswell Park Cancer Institute Buffalo, New York | Site Public Contact - (askroswell@roswellpark.org) |
| Rush - Copley Medical Center Aurora, Illinois | Site Public Contact - (Cancer.Research@rushcopley.com) |
| Rush-Copley Healthcare Center Yorkville, Illinois | Site Public Contact - (Cancer.Research@rushcopley.com) |
| SSM Health Good Samaritan Mount Vernon, Illinois | |
| Saint Agnes Hospital Baltimore, Maryland | |
| Saint Agnes Hospital/Agnesian Cancer Center Fond du Lac, Wisconsin | |
| Saint Alphonsus Cancer Care Center-Baker City Baker City, Oregon | Site Public Contact - (mccinfo@mtcancer.org) |
| Saint Alphonsus Cancer Care Center-Boise Boise, Idaho | Site Public Contact - (stephanie.couch@stjoeshealth.org) |
| Saint Alphonsus Cancer Care Center-Caldwell Caldwell, Idaho | Site Public Contact - (stephanie.couch@stjoeshealth.org) |
| Saint Alphonsus Cancer Care Center-Nampa Nampa, Idaho | Site Public Contact - (mccinfo@mtcancer.org) |
| Saint Alphonsus Cancer Care Center-Ontario Ontario, Oregon | Site Public Contact - (mccinfo@mtcancer.org) |
| Saint Ann's Hospital Westerville, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Saint Anthony Hospital Lakewood, Colorado | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Saint Anthony North Hospital Westminster, Colorado | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Saint Charles Health System Bend, Oregon | Site Public Contact - (nosall@stcharleshealthcare.org) |
| Saint Charles Health System-Redmond Redmond, Oregon | |
| Saint Claire Regional Medical Center Morehead, Kentucky | |
| Saint Elizabeth Boardman Hospital Boardman, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Saint Elizabeth Youngstown Hospital Youngstown, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Saint Francis Cancer Center Greenville, South Carolina | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Saint Francis Medical Center Cape Girardeau, Missouri | |
| Saint Francis Regional Medical Center Shakopee, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Saint George Regional Medical Center St. George, Utah | |
| Saint Helena Hospital St. Helena, California | |
| Saint James Community Hospital and Cancer Treatment Center Butte, Montana | |
| Saint John's Hospital - Healtheast Maplewood, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Saint Joseph Hospital - Cancer Centers of Colorado Denver, Colorado | |
| Saint Joseph Hospital - Orange Orange, California | |
| Saint Joseph Hospital East Lexington, Kentucky | |
| Saint Joseph London London, Kentucky | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Saint Joseph Radiation Oncology Resource Center Lexington, Kentucky | |
| Saint Joseph Warren Hospital Warren, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Saint Joseph's/Candler - Bluffton Campus Bluffton, South Carolina | Site Public Contact - (underberga@sjchs.org) |
| Saint Jude Medical Center Fullerton, California | |
| Saint Louis Cancer and Breast Institute-Ballwin Ballwin, Missouri | |
| Saint Louis Cancer and Breast Institute-South City St Louis, Missouri | |
| Saint Luke's Cancer Institute - Boise Boise, Idaho | Site Public Contact - (eslinget@slhs.org) |
| Saint Luke's Cancer Institute - Fruitland Fruitland, Idaho | Site Public Contact - (eslinget@slhs.org) |
| Saint Luke's Cancer Institute - Meridian Meridian, Idaho | Site Public Contact - (eslinget@slhs.org) |
| Saint Luke's Cancer Institute - Nampa Nampa, Idaho | Site Public Contact - (eslinget@slhs.org) |
| Saint Luke's Cancer Institute - Twin Falls Twin Falls, Idaho | Site Public Contact - (eslinget@slhs.org) |
| Saint Luke's East - Lee's Summit Lee's Summit, Missouri | Site Public Contact - (aroland@kccop.org) |
| Saint Luke's Hospital Chesterfield, Missouri | |
| Saint Luke's Hospital of Kansas City Kansas City, Missouri | Site Public Contact - (aroland@kccop.org) |
| Saint Luke's South Hospital Overland Park, Kansas | |
| Saint Mary Corwin Medical Center Pueblo, Colorado | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Saint Mary's Medical Center West Palm Beach, Florida | |
| Saint Mary's Oncology/Hematology Associates of Marlette Marlette, Michigan | |
| Saint Mary's Oncology/Hematology Associates of West Branch West Branch, Michigan | |
| Saint Mary's Regional Medical Center Reno, Nevada | Site Public Contact - (research@sncrf.org) |
| Saint Michael Cancer Center Silverdale, Washington | |
| Saint Patrick Hospital - Community Hospital Missoula, Montana | Site Public Contact - (amy.hanneman@providence.org) |
| Saint Peter's Community Hospital Helena, Montana | |
| Saint Rita's Medical Center Lima, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Saint Vincent Hospital Cancer Center Green Bay Green Bay, Wisconsin | Site Public Contact - (ewd_research_admin@hshs.org) |
| Saint Vincent Hospital Cancer Center at Marinette Marinette, Wisconsin | |
| Saint Vincent Hospital Cancer Center at Oconto Falls Oconto Falls, Wisconsin | Site Public Contact - (ewd_research_admin@hshs.org) |
| Saint Vincent Hospital Cancer Center at Saint Mary's Green Bay, Wisconsin | Site Public Contact - (ewd_research_admin@hshs.org) |
| Saint Vincent Hospital Cancer Center at Sheboygan Sheboygan, Wisconsin | Site Public Contact - (ewd_research_admin@hshs.org) |
| Saint Vincent Hospital Cancer Center at Sturgeon Bay Sturgeon Bay, Wisconsin | Site Public Contact - (ewd_research_admin@hshs.org) |
| Sainte Genevieve County Memorial Hospital Sainte Genevieve, Missouri | |
| Saints Mary and Elizabeth Hospital Louisville, Kentucky | |
| Salem Hospital Salem, Oregon | |
| Salina Regional Health Center Salina, Kansas | Site Public Contact - (mleepers@srhc.com) |
| Sandra L Maxwell Cancer Center Cedar City, Utah | |
| Sanford Bismarck Medical Center Bismarck, North Dakota | Site Public Contact - (OncologyClinicalTrialsFargo@sanfordhealth.org) |
| Sanford Broadway Medical Center Fargo, North Dakota | Site Public Contact - (OncologyClinicalTrialsFargo@sanfordhealth.org) |
| Sanford Cancer Center Oncology Clinic Sioux Falls, South Dakota | Site Public Contact - (OncologyClinicTrialsSF@sanfordhealth.org) |
| Sanford Cancer Center Worthington Worthington, Minnesota | |
| Sanford Joe Lueken Cancer Center Bemidji, Minnesota | Site Public Contact - (OncologyClinicalTrialsFargo@sanfordhealth.org) |
| Sanford Medical Center Fargo Fargo, North Dakota | |
| Sanford Roger Maris Cancer Center Fargo, North Dakota | Site Public Contact - (OncologyClinicalTrialsFargo@sanfordhealth.org) |
| Sanford South University Medical Center Fargo, North Dakota | |
| Sanford Thief River Falls Medical Center Thief River Falls, Minnesota | |
| Sanford USD Medical Center - Sioux Falls Sioux Falls, South Dakota | Site Public Contact - (OncologyClinicalTrialsSF@SanfordHealth.org) |
| Santa Cruz Radiation Oncology Medical Group Santa Cruz, California | Site Public Contact - (clinicalresearch@sutterhealth.org) |
| Sechler Family Cancer Center Lebanon, Pennsylvania | Site Public Contact - (doxenberg@wellspan.org) |
| Sheboygan Phyisicans Group Sheboygan, Wisconsin | Site Public Contact - (ewd_research_admin@hshs.org) |
| Shenandoah Oncology PC Winchester, Virginia | Site Public Contact - (William.Houck@usoncology.com) |
| Sinai Hospital of Baltimore Baltimore, Maryland | Site Public Contact - (pridgely@lifebridgehealth.org) |
| Singing River Hospital Pascagoula, Mississippi | |
| Siouxland Regional Cancer Center Sioux City, Iowa | Site Public Contact - (HoopingarnerT@jencc.com) |
| Siteman Cancer Center at Saint Peters Hospital City of Saint Peters, Missouri | Site Public Contact - (info@siteman.wustl.edu) |
| Siteman Cancer Center at West County Hospital Creve Coeur, Missouri | Site Public Contact - (info@siteman.wustl.edu) |
| Siteman Cancer Center-South County St Louis, Missouri | Site Public Contact - (info@siteman.wustl.edu) |
| Skagit Regional Health Cancer Care Center Mount Vernon, Washington | Site Public Contact - (rcccclinicalresearch@skagitvalleyhospital.org) |
| Smilow Cancer Center/Yale-New Haven Hospital New Haven, Connecticut | Site Public Contact - (canceranswers@yale.edu) |
| Smilow Cancer Hospital Care Center - Guilford Guilford, Connecticut | Site Public Contact - (canceranswers@yale.edu) |
| Smilow Cancer Hospital Care Center - Waterford Waterford, Connecticut | Site Public Contact - (canceranswers@yale.edu) |
| Smilow Cancer Hospital Care Center - Westerly Westerly, Rhode Island | Site Public Contact - (canceranswers@yale.edu) |
| Smilow Cancer Hospital Care Center at Saint Francis Hartford, Connecticut | Site Public Contact - (canceranswers@yale.edu) |
| Smilow Cancer Hospital Care Center-Fairfield Fairfield, Connecticut | Site Public Contact - (canceranswers@yale.edu) |
| Smilow Cancer Hospital Care Center-Trumbull Trumbull, Connecticut | Site Public Contact - (canceranswers@yale.edu) |
| Smilow Cancer Hospital-Derby Care Center Derby, Connecticut | Site Public Contact - (canceranswers@yale.edu) |
| Smilow Cancer Hospital-Orange Care Center Orange, Connecticut | Site Public Contact - (canceranswers@yale.edu) |
| Smilow Cancer Hospital-Torrington Care Center Torrington, Connecticut | Site Public Contact - (canceranswers@yale.edu) |
| Smilow Cancer Hospital-Waterbury Care Center Waterbury, Connecticut | Site Public Contact - (canceranswers@yale.edu) |
| Solinsky Center for Cancer Care Manchester, New Hampshire | |
| South Georgia Medical Center/Pearlman Cancer Center Valdosta, Georgia | Site Public Contact - (maryann.heddon@sgmc.org) |
| South Pointe Hospital Warrensville Heights, Ohio | Site Public Contact - (TaussigResearch@ccf.org) |
| South Sacramento Cancer Center Sacramento, California | Site Public Contact - (Kpoct@kp.org) |
| Southeast Cancer Center Cape Girardeau, Missouri | |
| Southeastern Medical Oncology Center-Clinton Clinton, North Carolina | |
| Southeastern Medical Oncology Center-Goldsboro Goldsboro, North Carolina | |
| Southeastern Medical Oncology Center-Jacksonville Jacksonville, North Carolina | |
| Southern Illinois University School of Medicine Springfield, Illinois | |
| Southern Ohio Medical Center Portsmouth, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Southpointe-Sanford Medical Center Fargo Fargo, North Dakota | |
| Southwest Oncology PC Durango, Colorado | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Spartanburg Medical Center Spartanburg, South Carolina | |
| Springfield Clinic Springfield, Illinois | |
| Springfield Memorial Hospital Springfield, Illinois | Site Public Contact - (pallante.beth@mhsil.com) |
| Springfield Regional Cancer Center Springfield, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Springfield Regional Medical Center Springfield, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Stamford Hospital/Bennett Cancer Center Stamford, Connecticut | |
| Stanford Cancer Institute Palo Alto Palo Alto, California | Site Public Contact - (ccto-office@stanford.edu) |
| Stephens Memorial Hospital Norway, Maine | |
| Straub Clinic and Hospital Honolulu, Hawaii | |
| Straub Medical Center - Kahului Clinic Kahului, Hawaii | Site Public Contact - (lori.kam@hawaiipacifichealth.org) |
| Straub Pearlridge Clinic ‘Aiea, Hawaii | |
| Strecker Cancer Center-Belpre Belpre, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Suburban Hematology Oncology Associates - Snellville Snellville, Georgia | Site Public Contact - (Clinical.trials@northside.com) |
| Summerlin Hospital Medical Center Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Sunrise Hospital and Medical Center Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Sutter Auburn Faith Hospital Auburn, California | Site Public Contact - (clinicalresearch@sutterhealth.org) |
| Sutter Cancer Centers Radiation Oncology Services-Auburn Auburn, California | Site Public Contact - (clinicalresearch@sutterhealth.org) |
| Sutter Cancer Centers Radiation Oncology Services-Cameron Park Cameron Park, California | Site Public Contact - (clinicalresearch@sutterhealth.org) |
| Sutter Cancer Centers Radiation Oncology Services-Roseville Roseville, California | Site Public Contact - (clinicalresearch@sutterhealth.org) |
| Sutter Cancer Research Consortium Novato, California | Site Public Contact - (clinicalresearch@sutterhealth.org) |
| Sutter Davis Hospital Davis, California | Site Public Contact - (NCIclinicaltrials@sutterhealth.org) |
| Sutter Medical Center Sacramento Sacramento, California | Site Public Contact - (clinicalresearch@sutterhealth.org) |
| Sutter Pacific Medical Foundation Santa Rosa, California | Site Public Contact - (clinicalresearch@sutterhealth.org) |
| Sutter Roseville Medical Center Roseville, California | Site Public Contact - (clinicalresearch@sutterhealth.org) |
| Sutter Solano Medical Center/Cancer Center Vallejo, California | Site Public Contact - (clinicalresearch@sutterhealth.org) |
| Swedish Cancer Institute-Edmonds Edmonds, Washington | Site Public Contact - (PCRC-NCORP@Swedish.org) |
| Swedish Cancer Institute-Issaquah Issaquah, Washington | Site Public Contact - (PCRC-NCORP@Swedish.org) |
| Swedish Covenant Hospital Chicago, Illinois | |
| Swedish Medical Center-Ballard Campus Seattle, Washington | Site Public Contact - (PCRC-NCORP@Swedish.org) |
| Swedish Medical Center-Cherry Hill Seattle, Washington | Site Public Contact - (PCRC-NCORP@Swedish.org) |
| Swedish Medical Center-First Hill Seattle, Washington | Site Public Contact - (PCRC-NCORP@Swedish.org) |
| Temple University Hospital Philadelphia, Pennsylvania | |
| Terrebonne General Medical Center Houma, Louisiana | Site Public Contact - (ann.hooks@tgmc.com) |
| The Cancer Center of Hawaii-Liliha Honolulu, Hawaii | |
| The Cancer Center of Hawaii-Pali Momi ‘Aiea, Hawaii | |
| The Cancer Institute at Saint Francis Hospital East Hills, New York | Site Public Contact - (Stephanie.Solito@chsli.org) |
| The Carle Foundation Hospital Urbana, Illinois | Site Public Contact - (Research@carle.com) |
| The Don and Sybil Harrington Cancer Center Amarillo, Texas | Site Public Contact - (Gina.Cravey@bsahs.org) |
| The Hospital of Central Connecticut New Britain, Connecticut | |
| The Mark H Zangmeister Center Columbus, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| The Melanoma and Skin Cancer Institute Englewood, Colorado | Site Public Contact - (ryan.weight@theskincancerinstitute.com) |
| The Permanente Medical Group-Roseville Radiation Oncology Roseville, California | Site Public Contact - (Kpoct@kp.org) |
| The Queen's Medical Center - West Oahu ‘Ewa Beach, Hawaii | Site Public Contact - (rohta@queens.org) |
| The University of Kansas Cancer Center - Olathe Olathe, Kansas | Site Public Contact - (atheCCResearch@kumc.edu) |
| The Women's Imaging Center Denver, Colorado | Site Public Contact - (info@westernstatesncorp.org) |
| Thomas Jefferson University Hospital Philadelphia, Pennsylvania | |
| Tibor Rubin VA Medical Center Long Beach, California | |
| TidalHealth Nanticoke / Allen Cancer Center Seaford, Delaware | |
| TidalHealth Peninsula Regional Salisbury, Maryland | Site Public Contact - (monika.naegeli@peninsula.org) |
| TidalHealth Richard A Henson Cancer Institute Ocean Pines, Maryland | Site Public Contact - (carol.messick@peninsula.org) |
| Torrance Memorial Medical Center Torrance, California | |
| Torrance Memorial Physician Network - Cancer Care Torrance, California | Site Public Contact - (courtney.steeneken@tmphysicians.com) |
| Tower Cancer Research Foundation Beverly Hills, California | Site Public Contact - (towercancerresearch@toweroncology.com) |
| TriHealth Cancer Institute-Anderson Cincinnati, Ohio | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| TriHealth Cancer Institute-Westside Cincinnati, Ohio | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Trinity Cancer Care Center Minot, North Dakota | |
| Trinity Health Grand Rapids Hospital Grand Rapids, Michigan | |
| Trinity Health IHA Medical Group Hematology Oncology - Brighton Brighton, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Trinity Health IHA Medical Group Hematology Oncology - Canton Canton, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital Chelsea, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus Ypsilanti, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Trinity Health Medical Center - Brighton Brighton, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Trinity Health Medical Center - Canton Canton, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Trinity Health Muskegon Hospital Muskegon, Michigan | |
| Trinity Health Saint Joseph Mercy Hospital Ann Arbor Ann Arbor, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Trinity Health Saint Joseph Mercy Oakland Hospital Pontiac, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Trinity Health Saint Mary Mercy Livonia Hospital Livonia, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Trinity's Tony Teramana Cancer Center Steubenville, Ohio | |
| UC Comprehensive Cancer Center at Silver Cross New Lenox, Illinois | Site Public Contact - (cancerclinicaltrials@bsd.uchicago.edu) |
| UC San Diego Moores Cancer Center La Jolla, California | Site Public Contact - (cancercto@ucsd.edu) |
| UCHealth Greeley Hospital Greeley, Colorado | Site Public Contact - (protocols@swog.org) |
| UCHealth Highlands Ranch Hospital Highlands Ranch, Colorado | |
| UCHealth Lone Tree Health Center Lone Tree, Colorado | Site Public Contact - (protocols@swog.org) |
| UCHealth Memorial Hospital Central Colorado Springs, Colorado | |
| UCHealth University of Colorado Hospital Aurora, Colorado | |
| UH Seidman Cancer Center at Firelands Regional Medical Center Sandusky, Ohio | |
| UH Seidman Cancer Center at Lake Health Mentor Campus Mentor, Ohio | |
| UH Seidman Cancer Center at Saint John Medical Center Westlake, Ohio | |
| UH Seidman Cancer Center at Southwest General Hospital Middleburg Heights, Ohio | |
| UHHS-Chagrin Highlands Medical Center Beachwood, Ohio | |
| UI Health Care Mission Cancer and Blood - Waukee Clinic Waukee, Iowa | |
| UM Sylvester Comprehensive Cancer Center at Aventura Aventura, Florida | |
| UM Sylvester Comprehensive Cancer Center at Coral Gables Coral Gables, Florida | |
| UM Sylvester Comprehensive Cancer Center at Deerfield Beach Deerfield Beach, Florida | |
| UM Sylvester Comprehensive Cancer Center at Kendall Miami, Florida | |
| UM Sylvester Comprehensive Cancer Center at Plantation Plantation, Florida | |
| UM Upper Chesapeake Medical Center Bel Air, Maryland | |
| UMass Memorial Medical Center - University Campus Worcester, Massachusetts | Site Public Contact - (cancer.research@umassmed.edu) |
| UNC REX Cancer Center of Wakefield Raleigh, North Carolina | Site Public Contact - (CancCtrOncologyClinicalResearch@unchealth.unc.edu) |
| UNC Rex Healthcare Raleigh, North Carolina | Site Public Contact - (CancCtrOncologyClinicalResearch@unchealth.unc.edu) |
| UPMC Altoona Altoona, Pennsylvania | |
| UPMC Camp Hill Camp Hill, Pennsylvania | |
| UPMC Cancer Center - Monroeville Monroeville, Pennsylvania | |
| UPMC Cancer Center at UPMC Horizon Farrell, Pennsylvania | |
| UPMC Cancer Center at UPMC McKeesport McKeesport, Pennsylvania | |
| UPMC Cancer Center at UPMC Northwest Seneca, Pennsylvania | |
| UPMC Cancer Center-Natrona Heights Natrona Heights, Pennsylvania | |
| UPMC Cancer Center-Uniontown Uniontown, Pennsylvania | |
| UPMC Cancer Center-Washington Washington, Pennsylvania | |
| UPMC Cancer Centers - Arnold Palmer Pavilion Greensburg, Pennsylvania | |
| UPMC Hamot Erie, Pennsylvania | |
| UPMC Hillman Cancer Center - Monroeville Monroeville, Pennsylvania | |
| UPMC Hillman Cancer Center - New Castle New Castle, Pennsylvania | |
| UPMC Hillman Cancer Center - Part of Frick Hospital Mount Pleasant, Pennsylvania | |
| UPMC Hillman Cancer Center - Passavant - Cranberry Cranberry Township, Pennsylvania | |
| UPMC Hillman Cancer Center Erie Erie, Pennsylvania | |
| UPMC Hillman Cancer Center at Butler Health System Butler, Pennsylvania | |
| UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion Mechanicsburg, Pennsylvania | Site Public Contact - (haneydl@upmc.edu) |
| UPMC Hillman Cancer Center in Coraopolis Moon Township, Pennsylvania | |
| UPMC Hillman Cancer Center in Greenville/UPMC Horizon Greenville, Pennsylvania | |
| UPMC Memorial York, Pennsylvania | |
| UPMC Pinnacle Cancer Center/Community Osteopathic Campus Harrisburg, Pennsylvania | Site Public Contact - (klitchfield@PINNACLEHEALTH.org) |
| UPMC Pinnacle Harrisburg Harrisburg, Pennsylvania | Site Public Contact - (protocols@swog.org) |
| UPMC Susquehanna Williamsport, Pennsylvania | |
| UPMC Uniontown Hospital Radiation Oncology Uniontown, Pennsylvania | |
| UPMC Washington Hospital Radiation Oncology Washington, Pennsylvania | |
| UPMC West Mifflin-Cancer Center Jefferson West Mifflin, Pennsylvania | |
| UPMC Western Maryland Cumberland, Maryland | |
| UPMC-Heritage Valley Health System Beaver Beaver, Pennsylvania | |
| UPMC-Johnstown/John P. Murtha Regional Cancer Center Johnstown, Pennsylvania | |
| UPMC-Mercy Hospital Pittsburgh, Pennsylvania | |
| UPMC-Passavant Hospital Pittsburgh, Pennsylvania | |
| UPMC-Saint Clair Hospital Cancer Center Pittsburgh, Pennsylvania | |
| UPMC-Saint Margaret Pittsburgh, Pennsylvania | |
| UT Southwestern Clinical Center at Richardson/Plano Richardson, Texas | Site Public Contact - (Suzanne.cole@utsouthwestern.edu) |
| UT Southwestern/Simmons Cancer Center-Dallas Dallas, Texas | Site Public Contact - (canceranswerline@UTSouthwestern.edu) |
| UT Southwestern/Simmons Cancer Center-Fort Worth Fort Worth, Texas | Site Public Contact - (canceranswerline@UTSouthwestern.edu) |
| UW Cancer Center at ProHealth Care Waukesha, Wisconsin | Site Public Contact - (Chanda.miller@phci.org) |
| Union Hospital Terre Haute, Indiana | |
| United Hospital Saint Paul, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Unity Hospital Fridley, Minnesota | |
| University Cancer Center Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| University Health Truman Medical Center Kansas City, Missouri | |
| University Hospitals Parma Medical Center Parma, Ohio | |
| University Hospitals Portage Medical Center Ravenna, Ohio | |
| University Hospitals Sharon Health Center Wadsworth, Ohio | |
| University Medical Center New Orleans New Orleans, Louisiana | |
| University Medical Center of Southern Nevada Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| University of Arizona Cancer Center-North Campus Tucson, Arizona | Site Public Contact - (UACC-IIT@uacc.arizona.edu) |
| University of Arkansas for Medical Sciences Little Rock, Arkansas | |
| University of California Davis Comprehensive Cancer Center Sacramento, California | |
| University of Chicago Comprehensive Cancer Center Chicago, Illinois | Site Public Contact - (cancerclinicaltrials@bsd.uchicago.edu) |
| University of Chicago Medicine-Orland Park Orland Park, Illinois | Site Public Contact - (cancerclinicaltrials@bsd.uchicago.edu) |
| University of Hawaii Cancer Center Honolulu, Hawaii | |
| University of Iowa Healthcare Cancer Services Quad Cities Bettendorf, Iowa | |
| University of Iowa/Holden Comprehensive Cancer Center Iowa City, Iowa | |
| University of Kansas Cancer Center Kansas City, Kansas | Site Public Contact - (KUCC_Navigation@kumc.edu) |
| University of Kansas Cancer Center - Lee's Summit Lee's Summit, Missouri | Site Public Contact - (KUCC_Navigation@kumc.edu) |
| University of Kansas Cancer Center - North Kansas City, Missouri | Site Public Contact - (KUCC_Navigation@kumc.edu) |
| University of Kansas Cancer Center at North Kansas City Hospital North Kansas City, Missouri | Site Public Contact - (KUCC_Navigation@kumc.edu) |
| University of Kansas Cancer Center-Overland Park Overland Park, Kansas | Site Public Contact - (KUCC_Navigation@kumc.edu) |
| University of Kansas Cancer Center-West Kansas City, Kansas | Site Public Contact - (KUCC_Navigation@kumc.edu) |
| University of Kansas Clinical Research Center Fairway, Kansas | Site Public Contact - (KUCC_Navigation@kumc.edu) |
| University of Kansas Health System Saint Francis Campus Topeka, Kansas | |
| University of Kansas Hospital-Indian Creek Campus Overland Park, Kansas | Site Public Contact - (KUCC_Navigation@kumc.edu) |
| University of Kansas Hospital-Westwood Cancer Center Westwood, Kansas | Site Public Contact - (KUCC_Navigation@kumc.edu) |
| University of Kentucky/Markey Cancer Center Lexington, Kentucky | |
| University of Maryland Shore Medical Center at Easton Easton, Maryland | |
| University of Maryland/Greenebaum Cancer Center Baltimore, Maryland | |
| University of Miami Miller School of Medicine-Sylvester Cancer Center Miami, Florida | |
| University of Michigan - Brighton Center for Specialty Care Brighton, Michigan | |
| University of Michigan Comprehensive Cancer Center Ann Arbor, Michigan | Site Public Contact - (slusserb@med.umich.edu) |
| University of Michigan Health - Sparrow Lansing Lansing, Michigan | Site Public Contact - (harsha.trivedi@umhsparrow.org) |
| University of Michigan Health - West Wyoming, Michigan | |
| University of Mississippi Medical Center Jackson, Mississippi | |
| University of New Mexico Cancer Center Albuquerque, New Mexico | Site Public Contact - (HSC-ClinicalTrialInfo@salud.unm.edu) |
| University of Oklahoma Health Sciences Center Oklahoma City, Oklahoma | Site Public Contact - (ou-clinical-trials@ouhsc.edu) |
| University of Pennsylvania/Abramson Cancer Center Philadelphia, Pennsylvania | |
| University of Pittsburgh Cancer Institute (UPCI) Pittsburgh, Pennsylvania | |
| University of Rochester Rochester, New York | |
| University of South Alabama Mitchell Cancer Institute Mobile, Alabama | |
| University of Vermont Medical Center Burlington, Vermont | Site Public Contact - (rpo@uvm.edu) |
| University of Vermont and State Agricultural College Burlington, Vermont | Site Public Contact - (rpo@uvm.edu) |
| University of Virginia Cancer Center Charlottesville, Virginia | |
| University of Washington Medical Center - Montlake Seattle, Washington | |
| University of Wisconsin Carbone Cancer Center - Eastpark Medical Center Madison, Wisconsin | Site Public Contact - (clinicaltrials@cancer.wisc.edu) |
| University of Wisconsin Carbone Cancer Center - University Hospital Madison, Wisconsin | Site Public Contact - (clinicaltrials@cancer.wisc.edu) |
| UofL Health Medical Center Northeast Louisville, Kentucky | |
| Upper Valley Medical Center Troy, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Urology Specialists of Nevada - Central Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Urology Specialists of Nevada - Green Valley Henderson, Nevada | Site Public Contact - (research@sncrf.org) |
| Urology Specialists of Nevada - Northwest Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Urology Specialists of Nevada - Southwest Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Utah Cancer Specialists-Salt Lake City Salt Lake City, Utah | |
| Utah Valley Regional Medical Center Provo, Utah | |
| VA Palo Alto Health Care System Palo Alto, California | |
| VCU Community Memorial Health Center South Hill, Virginia | Site Public Contact - (nemer.elmouallem@vcuhealth.org) |
| VCU Massey Cancer Center at Stony Point Richmond, Virginia | Site Public Contact - (ctoclinops@vcu.edu) |
| Valley Medical Center Renton, Washington | Site Public Contact - (research@valleymed.org) |
| Valley Radiation Oncology Peru, Illinois | |
| Veteran's Affairs Medical Center - Saint Louis St Louis, Missouri | Site Public Contact - (ctsucontact@westat.com) |
| Veterans Administration Medical Center - Birmingham Birmingham, Alabama | |
| Veterans Affairs Connecticut Healthcare System-West Haven Campus West Haven, Connecticut | |
| Veterans Affairs Loma Linda Healthcare System Loma Linda, California | |
| Veterans Affairs Medical Center - San Francisco San Francisco, California | |
| Vince Lombardi Cancer Clinic - Oshkosh Oshkosh, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Vince Lombardi Cancer Clinic-Sheboygan Sheboygan, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Vince Lombardi Cancer Clinic-Two Rivers Two Rivers, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Virginia Cancer Institute Richmond, Virginia | Site Public Contact - (smoore@vacancer.com) |
| Virginia Commonwealth University/Massey Cancer Center Richmond, Virginia | Site Public Contact - (CTOclinops@vcu.edu) |
| Virtua Samson Cancer Center Moorestown, New Jersey | Site Public Contact - (nctn@pennmedicine.upenn.edu) |
| Virtua Voorhees Voorhees Township, New Jersey | Site Public Contact - (nctn@pennmedicine.upenn.edu) |
| Waldo County General Hospital Belfast, Maine | |
| Walter Knox Memorial Hospital Emmett, Idaho | |
| Washington Hospital Fremont, California | |
| Washington University School of Medicine St Louis, Missouri | Site Public Contact - (info@siteman.wustl.edu) |
| Wayne Hospital Greenville, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Wayne Memorial Hospital Goldsboro, North Carolina | |
| Wayne State University/Karmanos Cancer Institute Detroit, Michigan | |
| Welch Cancer Center Sheridan, Wyoming | |
| WellSpan Health-York Cancer Center York, Pennsylvania | |
| WellSpan Health-York Hospital York, Pennsylvania | |
| WellSpan Medical Oncology and Hematology Chambersburg, Pennsylvania | |
| WellSpan Medical Oncology and Hematology Chambersburg, Pennsylvania | |
| West Michigan Cancer Center Kalamazoo, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
| West Virginia University Charleston Division Charleston, West Virginia | |
| West Virginia University Healthcare Morgantown, West Virginia | Site Public Contact - (cancertrialsinfo@hsc.wvu.edu) |
| Western Illinois Cancer Treatment Center Galesburg, Illinois | |
| Wheeling Hospital/Schiffler Cancer Center Wheeling, West Virginia | |
| White River Junction Veteran Administration Medical Center White River Junction, Vermont | |
| Wilcox Memorial Hospital and Kauai Medical Clinic Lihue, Hawaii | |
| William E Kahlert Regional Cancer Center/Sinai Hospital Westminster, Maryland | |
| Woodland Cancer Care Center Michigan City, Indiana | Site Public Contact - (sally.arnett@franciscanalliance.org) |
| Woodland Memorial Hospital Woodland, California | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Yale University New Haven, Connecticut | Site Public Contact - (canceranswers@yale.edu) |
| Yale-New Haven Hospital North Haven Medical Center North Haven, Connecticut | Site Public Contact - (canceranswers@yale.edu) |
| Zablocki Veterans Administration Medical Center Milwaukee, Wisconsin | |
| Zangmeister Center Grove City Grove City, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
Clazakizumab for the Treatment of Chronic Active Antibody Mediated Rejection in Kidney Transplant Recipients (IMAGINE)
Trial Registration Coordinator - clinicaltrials@cslbehring.com
Gupta, Gaurav
Phase 3
NCT03744910
HM20015883
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• Inclusion criteria:
• Age 18-75 years.
• Living donor/deceased donor kidney transplant recipients ≥6 months from time of transplant.
• Diagnosis of CABMR determined by kidney biopsy and the presence of HLA DSA using single-antigen bead-based assays. NOTE: If conducted within 12 months (+3 weeks) prior to the start of the screening period, and no intervening treatments have been administered, the biopsy does not need to be repeated at Screening. If conducted within 6 months (+ 3 weeks) prior to the start of Screening, the DSA analysis does not need to be repeated at screening. To be considered for determination of study eligibility, the biopsy and DSA analysis must be performed at least 2 months ± 2 weeks after the end of any prior treatment for ABMR (including CABMR) or TCMR, in order to show continuing CABMR and presence of HLA DSA. In addition, with the exception of steroids, treatments for ABMR or TCMR are not allowed within 3 months prior to the start of screening. The following histopathologic and serologic diagnostic criteria (based on Banff 2015 criteria [Loupy et al, 2017]) must be met for inclusion:
• Morphologic evidence of chronic tissue injury, as demonstrated by TG (cg>0). Biopsies without evidence of chronic tissue injury on light microscopy, but with glomerular basement membrane double contours on electron microscopy (cg1a) are eligible.
• Evidence of current/recent antibody interaction with vascular endothelium, including 1 or more of the following.
• Linear C4d staining in peritubular capillaries or medullary vasa recta (C4d2 or C4d3 by immunofluorescence on frozen sections, or C4d > 0 by immunohistochemistry on paraffin sections).
• At least moderate microvascular inflammation ([g + ptc] ≥ 2) in the absence of recurrent or de novo glomerulonephritis, although in the presence of acute TCMR, borderline infiltrate, or infection, ptc ≥ 2 alone is not sufficient and g must be ≥ 1. NOTE: The local pathologist's diagnosis must be reviewed by a central pathologist to confirm eligibility for entry into the study. Biopsies with other histopathologic changes (eg, BKV nephropathy or recurrent glomerulonephritis) may be eligible if concurrent CABMR changes (as detailed above) are present and determined to be the predominant cause of renal dysfunction.
• Serologic evidence of circulating DSA to HLA. NOTE: The local laboratory DSA results must be reviewed and confirmed by the central HLA reviewer during the screening period.
• Exclusion criteria:
• Multi-organ transplant recipient (except for simultaneous kidney-pancreas or previous multiple kidney transplants) or cell transplant (islet, bone marrow, stem cell) recipient.
• Treatment for ABMR (including CABMR) or TCMR within 3 months prior to the start of screening with the exception of steroids.
• Received T cell depleting agents (e.g., alemtuzumab, anti-thymocyte globulin) within 3 months prior to the start of screening.
• Pregnant, breastfeeding, or unwillingness to practice adequate contraception.
• Active tuberculosis (TB) or history of active TB.
• History of human immunodeficiency virus (HIV) infection or positive for HIV.
• Seropositive for hepatitis B surface antigen (HBsAg)
• Hepatitis C virus (HCV) RNA positive.
Biological: Clazakizumab, Drug: Physiologic saline solution
Antibody-mediated Rejection
Chronic Active, Antibody-mediated Rejection (AMR)
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Study Locations
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| Location | Contacts |
|---|---|
| Amsterdam UMC location AMC Amsterdam, | Study Co-ordinator |
| Amsterdam University Medical Center (Amsterdam UMC), Academic Medical Center (AMC) Amsterdam, | Use Central Contact |
| Beth Israel Deaconess Medical Center Boston, Massachusetts | Use Central Contact |
| CHU GRENOBLE ALPES - Consultation Néphrologie Bureau des ARC (Côté Chartreuse, Rez-de-Chaussée Haut) Grenoble, Grenoble Cédex 09 | Study Coordinator |
| CHU Rangueil Toulouse, | Study Coordinator |
| CHU de Nantes - Houtel Dieu Nantes Cedex 1, | Use Central Contact |
| California Institute Of Renal Research San Diego, California | Eva Gripp |
| California Pacific Medical Center San Francisco, California | Use Central Contact |
| Cedars-Sinai Medical Center Los Angeles, California | Use Central Contact |
| Central Pennsylvania Transplant Foundation Harrisburg, Pennsylvania | Study Coordinator |
| Centre Hospitalier Regional Universitaire (CHRU) Montpellier Arnaud de Villeneuve Montpellier, | Use Central Contact |
| Centre Hospitalier Regional Universitaire de Tours (CHRU de Tours) - Hopital Bretonneau Tours Cedex 9, | Use Central Contact |
| Centre Hospitalier Universitaire (CHU) - Hopital Henri Mondor Créteil, | Use Central Contact |
| Centre Hospitalier Universitaire (CHU) De Limoges Hopital Dupuytren Limoges Cedex, | Use Central Contact |
| Centre Hospitalier Universitaire (CHU) de Bordeaux - Groupe Hospitalier Pellegrin Bordeaux, | Use Central Contact |
| Centre Hospitalier Universitaire de Nice, Hopital Pasteur 2 Nice Cedex 1, | Use Central Contact |
| Centre Hospitalier Universitaire de Poitiers Poitiers, Vienne | Use Central Contact |
| Centro Hospital Universitario Dr. Preset Valencia, | Use Central Contact |
| Charite - Universitaetsmedizin Berlin - Campus Charite Mitte (CCM) Berlin, | Lead Study Coordinator |
| Columbia University Medical Center New York, New York | Study Coordinator |
| Debreceni Egyetem, Klinikai Központ, Auguszta Debrecen, | Study Coordinator |
| Duke Cancer Institute Durham, North Carolina | Use Central Contact |
| Erie County Medical Center Corp. Buffalo, New York | Use Central Contact |
| Henry Ford Health System Detroit, Michigan | Study Coordinator |
| Holden Comprehensive Cancer Center, University of Iowa Hospitals and Clinics Iowa City, Iowa | Use Central Contact |
| Hopital Edouard Herriot Lyon, | Study Coordinator |
| Hopital Kremlin Bicetre Le Kremlin-Bicêtre, | Use Central Contact |
| Hopital Necker Enfants Malades Paris, | Use Central Contact |
| Hopital de la Conception - APHM Marseille, | Use Central Contact |
| Hopitaux Universitaire de Strasbourg-Centre de References des Maladies Autoimmunes Strasbourg, | Use Central Contact |
| Hospital Clinic Barcelona Barcelona, | Study Coordinator |
| Hospital Clinico San Carlos Madrid, | Use Central Contact |
| Hospital Del Mar Barcelona, Catalonia | Study Coordinator |
| Hospital Saint-Louis - APHP Paris, | Use Central Contact |
| Hospital Universitari de Bellvitge Barcelona, | Study Coordinator |
| Hospital Universitario 12 de Octubre-Centro de Actividades Ambulatorias Madrid, | Use Central Contact |
| Hospital Universitario Marqués de Valdecilla Santander, | Use Central Contact |
| Hospital Universitario Miguel Servet Zaragoza, | Study Coordinator |
| Hospital Universitario Ramon y Cajal Madrid, | Use Central Contact |
| Hospital Vall d'Hebron Barcelona, | Use Central Contact |
| IKEM Prague, | Study Coordinator |
| Indiana University (IU) Health Physicians - Kidney Diseases Clinic - Medical Diagnostic Center Location Indianapolis, Indiana | Use Central Contact |
| Integris Baptist Medical Center Oklahoma City, Oklahoma | Use Central Contact |
| Jefferson University hospital Philadelphia, Pennsylvania | Use Central Contact |
| Kaiser Permanente Los Angeles, California | Use Central Contact |
| Karolinska University Hospital Stockholm, | Use Central Contact |
| Keck Medical Center of USC Los Angeles, California | USE CENTRAL CONTACT |
| Lehigh Valley Health Network Allentown, Pennsylvania | Use Central Contact |
| Leiden University Medical Center (LUMC) Leiden, | Use Central Contact |
| London Health Sciences Centre London, Ontario | Study Coordinator |
| Maastricht University Medical Centre Maastricht, | Use Central Contact |
| Massachusetts General Cancer Center Boston, Massachusetts | Use Central Contact |
| Mayo Clinic Rochester, Minnesota | Study Coordinator |
| Mayo Clinic Hospital Jacksonville, Florida | Study Coordinator |
| McGill University Health Center Montreal, Quebec | Use Central Contact |
| Medical College of WI Froedtert Hospital Milwaukee, Wisconsin | Use Central contact |
| Methodist Healthcare System of San Antonio San Antonio, Texas | Use Central Contact |
| Monash Health Monash Medical Centre Clayton, Victoria | Study Coordinator |
| NYU Langone Medical Center New York, New York | Study Coordinator |
| New York Presbyterian Hospital / Weill Cornell Medical Center New York, New York | Use Central Contact |
| North America Research Institute Lynwood, California | Use Central Contact |
| Northwestern Memorial Hospital Chicago, Illinois | Use Central Contact |
| Néphrologie - Pavillon Sainte Venise - CHU de Rouen - Hôpital de Bois Guillaume Bois-Guillaume, | Study Coordinator |
| Princess Alexandra Hospital Woolloongabba, | Trial Coordinator |
| Queen Elizabeth II Health Sciences Centre Halifax, Nova Scotia | Study Coordinator |
| Renal Disease Research Institute Dallas, Texas | Study Coordinator |
| Rhode Island Hospital Providence, Rhode Island | Use Central Contact |
| Royal Prince Alfred Hospital Camperdown, New South Wales | Study Coordinator |
| Rush University Medical Center - University Cardiovascular Surgeons Dallas, Texas | Use Central Contact |
| Saint Barnabas Medical Center Livingston, New Jersey | Use Central Contact |
| Shared Health Inc. operating as the Health Sciences Centre Winnipeg, Manitoba | Study Coordinator |
| Sir Charles Gairdner Hospital (SCGH) Nedlands, Western Australia | Use Central Contact |
| St Paul's Hospital Foundation Saskatoon, Saskatchewan | Use Central Contact |
| St. Michael's Health Centre Toronto, Ontario | Use Central Contact |
| St. Paul's Hospital, Providence Health Care, Univ. Of British Columbia Vancouver, British Columbia | Study Coordinator |
| Tampa General Medical Group Tampa, Florida | Use Central Contact |
| The Ohio State University, Comprehensive Transplant Center Columbus, Ohio | Use Central Contact |
| The Royal Melbourne Hospital Parkville, | Trial Coordinator |
| The University of Queensland - Princess Alexandra Hospital (PAH) Woolloongabba, Queensland | Use Central Contact |
| Tulane University Health Sciences Center New Orleans, Louisiana | Use Central Contact |
| UCLA Kidney Transplant Research Program Los Angeles, California | Use Central Contact |
| UT Southwestern Medical Center Dallas, Texas | Use Central Contact |
| Unity Point Health Des Moines, Iowa | Use Central Contact |
| University Medical Center Groningen Groningen, | Use Central Contact |
| University of Alabama at Birmingham (UAB) - University of Alabama Hospital (UAB Hospital) Birmingham, Alabama | Use Central Contact |
| University of California Davis Medical Center Sacramento, California | Use Central Contact |
| University of California, San Francisco Medical Center San Francisco, California | Use Cntral Contact |
| University of Cincinnati Cincinnati, Ohio | Use Central Contact |
| University of Colorado Hospital - Anschutz Medical Campus Aurora, Colorado | Use Central Contact |
| University of Louisville Research Foundation Louisville, Kentucky | Use Central Contact |
| University of Minnesota Minneapolis, Minnesota | Use Central Contact |
| University of Nebraska Medical Center Omaha, Nebraska | Research Assistant |
| University of Pennsylvania Philadelphia, Pennsylvania | Use Central Contact |
| University of Washington Seattle, Washington | Study Coordinator |
| University of Wisconsin School of Medicine and Public Health (UWSMPH) Madison, Wisconsin | Clinical Research Coordinator |
| Uppsala Universitet - Akademiska Sjukhuset Uppsala, | Use Central Contact |
| VCU Health Richmond, Virginia | Study Coordinator |
| Vancouver General Hospital - Gordon & Leslie Diamond Centre Vancouver, British Columbia | Study Coordinator |
| WSLHD, Westmead Hospital Westmead, New South Wales | Use Central Contact |
| Wake Forest University Health Sciences Winston-Salem, North Carolina | Study Coordinator |
| Washington University School of Medicine - Infectious Diseases (WU ID) Clinic Saint Louis, Missouri | Use Central Contact |
Durvalumab vs Placebo with Stereotactic Body Radiation Therapy in Early Stage NSLC (PACIFIC4)
Hamilton, Melanie, R - mrhamilton2@vcu.edu
Weiss, Elisabeth
III
NCT03833154
HM20018623
drug: Durvalumab, Modality: Immunotherapy
Lung
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Maggi, Rebecca - (maggir@vcu.edu) |
Semaglutide vs. Placebo in Subjects with NASH and Compensated Liver Cirrhosis
Grubb, Emily - Emily.Grubb@vcuhealth.org
Sanyal, Arun, J
II
NCT03987451
HM20016500
drug: Semaglutide
Diseases of Digestive System (520-579)
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Study Locations
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Grubb, Emily - (Emily.Grubb@vcuhealth.org) |
Study Of Palbociclib Combined With Chemotherapy In Pediatric Patients With Recurrent/Refractory Solid Tumors (A5481092)
Pfizer CT.gov Call Center - ClinicalTrials.gov_Inquiries@pfizer.com
Austin, Frances
Phase 2
NCT03709680
HM20017464
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Inclusion:
• Histologically confirmed relapsed or refractory solid tumor as follows:
• For dose escalation and dose determination parts: Histologically confirmed relapsed or refractory solid tumor (including CNS tumors but not lymphomas). Patients with Diffuse Intrinsic Pontine Glioma do not require histological only radiographic confirmed relapse to enroll.
• For dose expansion and tumor specific cohorts: Histologically confirmed relapsed or refractory solid tumor including but not limited to EWS, rhabdoid tumor, rhabdomyosarcoma, neuroblastoma, and medulloblastoma. Patients with Diffuse Intrinsic Pontine Glioma do not require histological only radiographic confirmed relapse to enroll. EWS is not eligible for TOPO and CTX tumor-specific cohorts.
• For randomized Phase 2 part: Histologically confirmed Ewing sarcoma at diagnosis or at relapse, with presence of EWSR1-ETS or FUS-ETS rearrangement. Histopathology confirmation of both EWSR1-ETS or FUS-ETS rearrangement partners is required OR availability of formalin fixed paraffin embedded (FFPE) tumor tissue sample for central testing. Patient must have relapsed or have refractory disease and at least evaluable disease in at least one site other than bone marrow that can be followed by imaging.
• Age ≥2 and <21 years at the time of study entry.
• Lansky performance status ≥50% for patients ≤16 years of age, or Eastern Cooperative Oncology Group (ECOG) 0, 1 or 2 for patients >16 years of age.
• Adequate bone marrow function.
• Absolute neutrophil count ≥1000/mm3;
• Platelet count ≥100,000/mm3 (transfusion independent, no platelet transfusion in past 7 days prior study entry);
• Hemoglobin ≥8.5 g/dL (transfusion allowed).
• Adequate renal function: Serum creatinine level based on age/gender must within protocol specified limits.
• Adequate liver function, including:
• Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) ≤2.5 × upper limit of normal (ULN) or ≤5 × ULN for age, if attributable to disease involvement of the liver;
• Total bilirubin ≤1.5 × ULN for age, unless the patient has documented Gilbert's syndrome.
• Patients enrolled to Phase 1 portion of the study and tumor specific cohorts must have measurable disease as defined by RECIST version 1.1 or modified RANO criteria for CNS disease or INRC for neuroblastoma. Patients with EWS enrolled to Phase 2 portion of the study are eligible with evaluable disease (eg, bone only disease with no soft tissue component).
• Recovered to CTCAE Grade ≤1, or to baseline, from any non-hematological acute toxicities of prior surgery, chemotherapy, immunotherapy, radiotherapy, differentiation therapy or biologic therapy, with the exception of alopecia.
• Serum/urine pregnancy test (for all girls ≥8 years of age) negative at screening and at the baseline visit. Exclusion:
• Phase 1 and tumor specific cohorts: For palbociclib with IRN and TMZ combination, prior treatment with a CDK4/6 inhibitor or progression while on treatment with an IRN-containing regimen that includes TMZ. Patients who have received the combination of IRN and TMZ and did not progress while on these medications are eligible. For patients enrolling in the palbociclib with TOPO and CTX combination, prior treatment with a CDK4/6 inhibitor or progression while on treatment with a TOPO-containing regimen that includes CTX. Patients who have received the combination of TOPO and CTX and did not progress while on these medications are eligible. Phase 2 portion: prior treatment with a CDK4/6 inhibitor or progression while on treatment with an IRN-containing or TMZ-containing regimen. Patients who have received IRN and/or TMZ and did not progress while on these medications are eligible.
• Prior intolerability to IRN and/or TMZ plus/minus palbociclib with IRN and TMZ combination and prior intolerability to TOPO and/or CTX for TOPO and CTX combination.
• Use of strong cytochrome P450 (CYP) 3A inhibitors or inducers. Patients who are receiving strong uridine diphosphate-glucuronosyl transferase 1A1 (UGT1A1) inhibitors within 12 days of Cycle 1 Day 1 (C1D1) are not eligible for the palbociclib with IRN and TMZ combination. Patients who are receiving strong UGT1A1 inhibitors within 12 days of C1D1 are eligible for the palbociclib with TOPO and CTX combination (See Section 5.7.1 for list of products.)
• Systemic anti cancer therapy within 2 weeks prior to study entry and 6 weeks for nitrosoureas.
• Prior irradiation to >50% of the bone marrow (see Appendix 9).
• Participation in other studies involving investigational drug(s) within 2 weeks or 5 half lives, whichever is longer, prior to study entry.
• Major surgery within 4 weeks prior to study entry. Surgical biopsies or central line placement are not considered major surgeries.
• For IRN and TMZ with/without palbociclib combinations: known or suspected hypersensitivity to palbociclib, IRN and/or TMZ. For combination of palbociclib with TOPO and CTX: known or suspected hypersensitivity to palbociclib, TOPO and/or CTX.
• Patients with known symptomatic brain tumors or brain metastases and require steroids, unless they have been on a stable or on a decreasing steroid dose for >14 days.
• Patients with previously diagnosed brain metastases are eligible if they have completed their prior treatment and have recovered from the acute effects of radiation therapy or surgery prior to study entry for these metastases for at least 14 days post radiation and 4 weeks post-surgery and are neurologically stable.
• Hereditary bone marrow failure disorder.
• QTc >470 msec.
• History of clinically significant or uncontrolled cardiac disease, including:
• History of or active congestive heart failure; if patient had congestive heart failure resolve and >1 year from resolution, patient will be considered eligible;
• Clinically significant ventricular arrhythmia (such as ventricular tachycardia, ventricular fibrillation or Torsades de Pointes);
• Diagnosed or suspected congenital or acquired prolonged QT syndrome;
• Need for medications known to prolong the QT interval;
• Uncorrected hypomagnesemia or hypokalemia because of potential effects on the QT interval;
• Left ventricular ejection fraction <50% or shortening fraction <28%.
• Recent or ongoing clinically significant gastrointestinal disorder that may interfere with absorption of orally administered drugs (eg, gastrectomy).
• Severe acute or chronic medical or laboratory test abnormality that may increase the risk associated with study participation or investigational product administration or may interfere with the interpretation of study results, and in the judgment of the Investigator, would make the patient inappropriate for entry into this study.
• Investigator site staff members directly involved in the conduct of the study and their family members, site staff members otherwise supervised by the investigator, or patients who are Pfizer employees, including their family members, directly involved in the conduct of the study.
• Histologically confirmed relapsed or refractory solid tumor as follows:
• For dose escalation and dose determination parts: Histologically confirmed relapsed or refractory solid tumor (including CNS tumors but not lymphomas). Patients with Diffuse Intrinsic Pontine Glioma do not require histological only radiographic confirmed relapse to enroll.
• For dose expansion and tumor specific cohorts: Histologically confirmed relapsed or refractory solid tumor including but not limited to EWS, rhabdoid tumor, rhabdomyosarcoma, neuroblastoma, and medulloblastoma. Patients with Diffuse Intrinsic Pontine Glioma do not require histological only radiographic confirmed relapse to enroll. EWS is not eligible for TOPO and CTX tumor-specific cohorts.
• For randomized Phase 2 part: Histologically confirmed Ewing sarcoma at diagnosis or at relapse, with presence of EWSR1-ETS or FUS-ETS rearrangement. Histopathology confirmation of both EWSR1-ETS or FUS-ETS rearrangement partners is required OR availability of formalin fixed paraffin embedded (FFPE) tumor tissue sample for central testing. Patient must have relapsed or have refractory disease and at least evaluable disease in at least one site other than bone marrow that can be followed by imaging.
• Age ≥2 and <21 years at the time of study entry.
• Lansky performance status ≥50% for patients ≤16 years of age, or Eastern Cooperative Oncology Group (ECOG) 0, 1 or 2 for patients >16 years of age.
• Adequate bone marrow function.
• Absolute neutrophil count ≥1000/mm3;
• Platelet count ≥100,000/mm3 (transfusion independent, no platelet transfusion in past 7 days prior study entry);
• Hemoglobin ≥8.5 g/dL (transfusion allowed).
• Adequate renal function: Serum creatinine level based on age/gender must within protocol specified limits.
• Adequate liver function, including:
• Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) ≤2.5 × upper limit of normal (ULN) or ≤5 × ULN for age, if attributable to disease involvement of the liver;
• Total bilirubin ≤1.5 × ULN for age, unless the patient has documented Gilbert's syndrome.
• Patients enrolled to Phase 1 portion of the study and tumor specific cohorts must have measurable disease as defined by RECIST version 1.1 or modified RANO criteria for CNS disease or INRC for neuroblastoma. Patients with EWS enrolled to Phase 2 portion of the study are eligible with evaluable disease (eg, bone only disease with no soft tissue component).
• Recovered to CTCAE Grade ≤1, or to baseline, from any non-hematological acute toxicities of prior surgery, chemotherapy, immunotherapy, radiotherapy, differentiation therapy or biologic therapy, with the exception of alopecia.
• Serum/urine pregnancy test (for all girls ≥8 years of age) negative at screening and at the baseline visit. Exclusion:
• Phase 1 and tumor specific cohorts: For palbociclib with IRN and TMZ combination, prior treatment with a CDK4/6 inhibitor or progression while on treatment with an IRN-containing regimen that includes TMZ. Patients who have received the combination of IRN and TMZ and did not progress while on these medications are eligible. For patients enrolling in the palbociclib with TOPO and CTX combination, prior treatment with a CDK4/6 inhibitor or progression while on treatment with a TOPO-containing regimen that includes CTX. Patients who have received the combination of TOPO and CTX and did not progress while on these medications are eligible. Phase 2 portion: prior treatment with a CDK4/6 inhibitor or progression while on treatment with an IRN-containing or TMZ-containing regimen. Patients who have received IRN and/or TMZ and did not progress while on these medications are eligible.
• Prior intolerability to IRN and/or TMZ plus/minus palbociclib with IRN and TMZ combination and prior intolerability to TOPO and/or CTX for TOPO and CTX combination.
• Use of strong cytochrome P450 (CYP) 3A inhibitors or inducers. Patients who are receiving strong uridine diphosphate-glucuronosyl transferase 1A1 (UGT1A1) inhibitors within 12 days of Cycle 1 Day 1 (C1D1) are not eligible for the palbociclib with IRN and TMZ combination. Patients who are receiving strong UGT1A1 inhibitors within 12 days of C1D1 are eligible for the palbociclib with TOPO and CTX combination (See Section 5.7.1 for list of products.)
• Systemic anti cancer therapy within 2 weeks prior to study entry and 6 weeks for nitrosoureas.
• Prior irradiation to >50% of the bone marrow (see Appendix 9).
• Participation in other studies involving investigational drug(s) within 2 weeks or 5 half lives, whichever is longer, prior to study entry.
• Major surgery within 4 weeks prior to study entry. Surgical biopsies or central line placement are not considered major surgeries.
• For IRN and TMZ with/without palbociclib combinations: known or suspected hypersensitivity to palbociclib, IRN and/or TMZ. For combination of palbociclib with TOPO and CTX: known or suspected hypersensitivity to palbociclib, TOPO and/or CTX.
• Patients with known symptomatic brain tumors or brain metastases and require steroids, unless they have been on a stable or on a decreasing steroid dose for >14 days.
• Patients with previously diagnosed brain metastases are eligible if they have completed their prior treatment and have recovered from the acute effects of radiation therapy or surgery prior to study entry for these metastases for at least 14 days post radiation and 4 weeks post-surgery and are neurologically stable.
• Hereditary bone marrow failure disorder.
• QTc >470 msec.
• History of clinically significant or uncontrolled cardiac disease, including:
• History of or active congestive heart failure; if patient had congestive heart failure resolve and >1 year from resolution, patient will be considered eligible;
• Clinically significant ventricular arrhythmia (such as ventricular tachycardia, ventricular fibrillation or Torsades de Pointes);
• Diagnosed or suspected congenital or acquired prolonged QT syndrome;
• Need for medications known to prolong the QT interval;
• Uncorrected hypomagnesemia or hypokalemia because of potential effects on the QT interval;
• Left ventricular ejection fraction <50% or shortening fraction <28%.
• Recent or ongoing clinically significant gastrointestinal disorder that may interfere with absorption of orally administered drugs (eg, gastrectomy).
• Severe acute or chronic medical or laboratory test abnormality that may increase the risk associated with study participation or investigational product administration or may interfere with the interpretation of study results, and in the judgment of the Investigator, would make the patient inappropriate for entry into this study.
• Investigator site staff members directly involved in the conduct of the study and their family members, site staff members otherwise supervised by the investigator, or patients who are Pfizer employees, including their family members, directly involved in the conduct of the study.
Drug: Palbociclib, Drug: Temozolomide, Drug: Irinotecan, Drug: Topotecan, Drug: Cyclophosphamide
Ewing Sarcoma, Solid Tumors, Rhabdoid Tumor, Rhabdomyosarcoma, Neuroblastoma, Medulloblastoma, Diffuse Intrinsic Pontine Glioma
Ewing Sarcoma, EWS, Solid Tumor, Recurrent Solid Tumors, Refractory Solid Tumors, Bone Cancer, Bone Tumor, Bone Sarcoma, Soft Tissue Cancer, Soft Tissue Sarcoma, Recurrent Ewing Sarcoma, Refractory Ewing Sarcoma, Relapsed Ewing Sarcoma, Pediatric Cancer, Childhood Cancer, Ewing Sarcoma Treatment, Palbociclib, CDK4/6 Inhibitor, Irinotecan, Temozolomide, Topotecan, Cyclophosphamide
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Show 108 locations
Study Locations
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| Location | Contacts |
|---|---|
| Alberta Children's Hospital Calgary, Alberta | |
| All India Institute of Medical Sciences New Delhi, National Capital Territory of Delhi | |
| Ann & Robert H. Lurie Children's Hospital of Chicago Chicago, Illinois | |
| Arnold Palmer Hospital for Children Orlando, Florida | |
| Artemis Hospital Gurgaon, Haryana | |
| Asan Medical Center Seoul, | |
| Assistance Publique Hôpitaux de Marseille - Hôpital de la Timone Marseille, | |
| Astrid Lindgrens Barnsjukhus Stockholm, | |
| BIONT, a.s. Bratislava, | |
| Borsod-Abaúj-Zemplén Megyei Központi Kórház és Egyetemi Oktatókórház Miskolc, Borsod-abaúj-zemplén | |
| Buerger Center for Advanced Pediatric Care Philadelphia, Pennsylvania | |
| CHU Sainte-Justine Montréal, Quebec | |
| Carolinas Medical Center/Levine Children's Hospital Charlotte, North Carolina | |
| Children's Blood and Cancer Center Austin, Texas | |
| Children's Healthcare of Atlanta at Egleston Atlanta, Georgia | |
| Children's Healthcare of Atlanta at Scottish Rite Atlanta, Georgia | |
| Children's Healthcare of Atlanta, Medical Office Building Atlanta, Georgia | |
| Children's Hospital Colorado Aurora, Colorado | |
| Children's Hospital Los Angeles Los Angeles, California | |
| Children's Hospital and Research Center at Oakland Oakland, California | |
| Children's Hospital of Orange County Orange, California | |
| Children's Hospital of Philadelphia Philadelphia, Pennsylvania | |
| Children's Hospital of Richmond at VCU Richmond, Virginia | |
| Children's Hospital of the King's Daughters Norfolk, Virginia | |
| Children's Medical Center Dallas Dallas, Texas | |
| Children's Medical Center Plano Plano, Texas | |
| Children's Mercy Hospital Kansas City, Missouri | |
| Children's National Medical Center Washington D.C., District of Columbia | |
| Children's Of Alabama Birmingham, Alabama | |
| Children's Wisconsin Milwaukee, Wisconsin | |
| Cincinnati Children's Hospital Medical Center Cincinnati, Ohio | |
| Cincinnati Children's Liberty Campus Liberty Township, Ohio | |
| Cohen Children's Medical Center Queens, New York | |
| Connecticut Children's Medical Center Hartford, Connecticut | |
| Cook Children's H/O Infusion Center Grapevine, Texas | |
| Cook Children's Medical Center Fort Worth, Texas | |
| Dana-Farber Cancer Institute Boston, Massachusetts | |
| Dell Children's Medical Center Austin, Texas | |
| Detska Fakultna nemocnica s poliklinikou Banska Bystrica Banska Bystrica, | |
| Ege Universitesi Hastanesi Izmir, | |
| Fakultna nemocnica s poliklinikou F. D. Roosevelta Banska Bystrica, Oddelenie radiologie Banska Bystrica, | |
| Fakultni nemocnice v Motole Prague, | |
| Fundação Pio XII - Hospital de Câncer de Barretos Barretos, São Paulo | |
| Gustave Roussy Villejuif, | |
| Hacettepe Universite Hastaneleri Ankara, | |
| Hackensack University Medical Center Hackensack, New Jersey | |
| Hospital Infantil Universitario Nino Jesus Madrid, | |
| Hospital Sant Joan de Deu Barcelona, | |
| Hospital Universitari Vall d'Hebron Barcelona, | |
| Hospital Universitari i Politécnic La Fe Valencia, | |
| Hospital Universitario Virgen del Rocio Seville, | |
| Indiana University Indianapolis, Indiana | |
| Institut Bergonié - Centre Régional de Lutte Contre Le Cancer de Bordeaux et Sud Ouest Bordeaux, Aquitaine | |
| Institut nuklearnej a molekularnej mediciny Banska Bystrica, | |
| Instytut Matki i Dziecka Warsaw, Mazowieckie | |
| Intermountain - Primary Children's Hospital Salt Lake City, Utah | |
| Johns Hopkins All Children's Hospital St. Petersburg, Florida | |
| Johns Hopkins All Children's Hospital St. Petersburg, Florida | |
| Johns Hopkins All Children's Outpatient Care Center Saint Petersburg, Florida | |
| Johns Hopkins University Baltimore, Maryland | |
| Kapiolani Medical Center for Women and Children Honolulu, Hawaii | |
| Lucile Packard Children's Hospital Palo Alto, California | |
| Mayo Clinic in Rochester, Minnesota Rochester, Minnesota | |
| Medical College of Wisconsin Milwaukee, Wisconsin | |
| MemorialCare Health System - Long Beach Medical Center Long Beach, California | |
| Montefiore Medical Center The Bronx, New York | |
| Morgan Stanley Children's Hospital of New York-Presbyetrian Hospital New York, New York | |
| Narodny ustav detskych chorob Bratislava, | |
| Narodny ustav detskych chorob Bratislava, | |
| National Cancer Center Goyang-si Gyeonggi-do, | |
| Nationwide Children's Hospital Columbus, Ohio | |
| Norton Children's Hospital Louisville, Kentucky | |
| Novak Center for Children's Health Louisville, Kentucky | |
| Oregon Health & Science University Portland, Oregon | |
| Pecsi Tudomanyegyetem Klinikai Kozpont Pecs, | |
| Penn State Children's Hospital and Penn State Health Milton S. Hershey Medical Center Hershey, Pennsylvania | |
| Penn State Health Milton S. Hershey Medical Center Hershey, Pennsylvania | |
| Phoenix Children's Hospital Phoenix, Arizona | |
| Primary Children's Hospital Outpatient Services Salt Lake City, Utah | |
| Rajiv Gandhi Cancer Institute And Research Centre New Delhi, National Capital Territory of Delhi | |
| Robert Wood Johnson University Hospital New Brunswick, New Jersey | |
| Rutgers Cancer Institute of New Jersey New Brunswick, New Jersey | |
| SUNY Upstate Medical University Syracuse, New York | |
| Sahlgrenska Universitetssjukhuset Östra Gothenburg, | |
| Samsung Medical Center Seoul, | |
| Seattle Children's Hospital Seattle, Washington | |
| Seoul National University Hospital Seoul, | |
| Stollery Children's Hospital Edmonton, Alberta | |
| Texas Children's Hospital Houston, Texas | |
| The Hospital for Sick Children Toronto, Ontario | |
| Torrence E. Hemby Jr. Pediatric Hematology & Oncology Center Charlotte, North Carolina | |
| UCSF Medical Center San Francisco, California | |
| UF Health Shands Hospital Gainesville, Florida | |
| UMHAT Tsaritsa Yoanna-ISUL EAD Sofia, | |
| UPMC Children's Hospital of Pittsburgh Pittsburgh, Pennsylvania | |
| University Hospitals Cleveland Medical Center Cleveland, Ohio | |
| University of California San Francisco, San Francisco, California | |
| University of Florida College of Medicine Jacksonville, Florida | |
| University of Illinois College of Medicine at Peoria Peoria, Illinois | |
| University of Michigan Health System Ann Arbor, Michigan | |
| University of Minnesota Minneapolis, Minnesota | |
| University of Minnesota Masonic Children's Hospital Minneapolis, Minnesota | |
| University of Minnesota Medical Center, Fairview Minneapolis, Minnesota | |
| University of Minnesota/Masonic Cancer Center Minneapolis, Minnesota | |
| University of Mississippi Medical Center Jackson, Mississippi | |
| University of Oklahoma Health Sciences Center Oklahoma City, Oklahoma | |
| Uniwersytecki Szpital Kliniczny im. Jana Mikulicza-Radeckiego we Wroclawiu Wroclaw, | |
| Washington University School of Medicine St Louis, Missouri |
Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy
Gwaltney, Lindsey - lbgwaltney@vcu.edu
Griffin, Jordyn
PHASE3
NCT03959085
HM20018568
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Inclusion Criteria:
* B-ALL and MPAL patients must be enrolled on APEC14B1 and consented to eligibility studies (Part A) prior to treatment and enrollment on AALL1732. Note that central confirmation of MPAL diagnosis must occur within 22 days of enrollment for suspected MPAL patients. If not performed within this time frame, patients will be taken off protocol.
* APEC14B1 is not a requirement for B-LLy patients but for institutional compliance every patient should be offered participation in APEC14B1. B-LLy patients may directly enroll on AALL1732.
* Patients must be \> 365 days and \< 25 years of age
* White blood cell count (WBC) criteria for patients with B-ALL (within 7 days prior to the start of protocol-directed systemic therapy):
* Age 1-9.99 years: WBC \>= 50,000/uL
* Age 10-24.99 years: Any WBC
* Age 1-9.99 years: WBC \< 50,000/uL with:
* Testicular leukemia
* CNS leukemia (CNS3)
* Steroid pretreatment.
* White blood cell count (WBC) criteria for patients with MPAL (within 7 days prior to the start of protocol-directed systemic therapy):
* Age 1-24.99 years: any WBC NOTE: Patients enrolled as suspected MPAL but found on central confirmatory testing to have B-ALL must meet the B-ALL criteria above (age, WBC, extramedullary disease, steroid pretreatment) to switch to the B-ALL stratum before the end of induction.
* Patient has newly diagnosed B-ALL or MPAL (by World Health Organization \[WHO\] 2016 criteria) with \>= 25% blasts on a bone marrow (BM) aspirate;
* OR If a BM aspirate is not obtained or is not diagnostic of acute leukemia, the diagnosis can be established by a pathologic diagnosis of acute leukemia on a BM biopsy;
* OR A complete blood count (CBC) documenting the presence of at least 1,000/uL circulating leukemic cells if a bone marrow aspirate or biopsy cannot be performed.
* Patient has newly diagnosed B-LLy Murphy stages III or IV.
* Patient has newly diagnosed B-LLy Murphy stages I or II with steroid pretreatment.
* Note: For B-LLy patients with tissue available for flow cytometry, the criterion for diagnosis should be analogous to B-ALL. For tissue processed by other means (i.e., paraffin blocks), the methodology and criteria for immunophenotypic analysis to establish the diagnosis of B-LLy defined by the submitting institution will be accepted.
* Central nervous system (CNS) status must be determined prior to enrollment based on a sample obtained prior to administration of any systemic or intrathecal chemotherapy, except for steroid pretreatment and cytoreduction. It is recommended that intrathecal cytarabine be administered at the time of the diagnostic lumbar puncture. This is usually done at the time of the diagnostic bone marrow or venous line placement to avoid a second lumbar puncture. This is allowed prior to enrollment. Systemic chemotherapy must begin within 72 hours of this intrathecal therapy.
* All patients and/or their parents or legal guardians must sign a written informed consent.
* All institutional, Food and Drug Administration (FDA), and NCI requirements for human studies must be met.
Exclusion Criteria:
* Patients with Down syndrome are not eligible (patients with Down syndrome and B-ALL are eligible for AALL1731, regardless of NCI risk group).
* With the exception of steroid pretreatment and steroid cytoreduction or the administration of intrathecal cytarabine, patients must not have received any prior cytotoxic chemotherapy for the current diagnosis of B-ALL, MPAL, or B-LLy or for any cancer diagnosed prior to initiation of protocol therapy on AALL1732.
* Patients who have received \> 72 hours of hydroxyurea within one week prior to start of systemic protocol therapy.
* Patients with B-ALL or MPAL who do not have sufficient diagnostic bone marrow submitted for APEC14B1 testing and who do not have a peripheral blood sample submitted containing \> 1,000/uL circulating leukemia cells.
* Patients with acute undifferentiated leukemia (AUL) are not eligible.
* For Murphy stage III/IV B-LLy patients, or stage I/II patients with steroid pretreatment, the following additional exclusion criteria apply:
* T-lymphoblastic lymphoma.
* Morphologically unclassifiable lymphoma.
* Absence of both B-cell and T-cell phenotype markers in a case submitted as lymphoblastic lymphoma.
* Patients with known Charcot-Marie-Tooth disease.
* Patients with known MYC translocation associated with mature (Burkitt) B-cell ALL, regardless of blast immunophenotype.
* Patients requiring radiation at diagnosis.
* Female patients who are pregnant, since fetal toxicities and teratogenic effects have been noted for several of the study drugs. A pregnancy test is required for female patients of childbearing potential.
* Lactating women who plan to breastfeed their infants while on study and for 2 months after the last dose of inotuzumab ozogamicin.
* Sexually active patients of reproductive potential who have not agreed to use an effective contraceptive method for the duration of study participation. For those patients randomized to inotuzumab ozogamicin, there is a minimum of 8 months after the last dose of inotuzumab ozogamicin for females and 5 months after the last dose of inotuzumab ozogamicin for males. PROCEDURE: Biospecimen Collection, PROCEDURE: Bone Marrow Aspiration, PROCEDURE: Bone Marrow Biopsy, PROCEDURE: Bone Scan, DRUG: Calaspargase Pegol, PROCEDURE: Computed Tomography, DRUG: Cyclophosphamide, DRUG: Cytarabine, DRUG: Daunorubicin Hydrochloride, DRUG: Dexamethasone, DRUG: Doxorubicin Hydrochloride, BIOLOGICAL: Inotuzumab Ozogamicin, DRUG: Leucovorin Calcium, PROCEDURE: Magnetic Resonance Imaging, DRUG: Mercaptopurine, DRUG: Methotrexate, DRUG: Pegaspargase, PROCEDURE: Positron Emission Tomography, DRUG: Prednisolone, OTHER: Questionnaire Administration, RADIATION: Radiation Therapy, RADIATION: Radiation Therapy, DRUG: Thioguanine, DRUG: Vincristine Sulfate
B Acute Lymphoblastic Leukemia, B Lymphoblastic Lymphoma, Central Nervous System Leukemia, Mixed Phenotype Acute Leukemia, Testicular Leukemia
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Study Locations
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| Location | Contacts |
|---|---|
| AdventHealth Orlando Orlando, Florida | Site Public Contact - (FH.Cancer.Research@flhosp.org) |
| Advocate Children's Hospital-Oak Lawn Oak Lawn, Illinois | |
| Advocate Children's Hospital-Park Ridge Park Ridge, Illinois | Site Public Contact - (helpdesk@childrensoncologygroup.org) |
| Albany Medical Center Albany, New York | |
| Alberta Children's Hospital Calgary, Alberta | Site Public Contact - (research4kids@ucalgary.ca) |
| Alfred I duPont Hospital for Children Wilmington, Delaware | Site Public Contact - (Allison.bruce@nemours.org) |
| Alliance for Childhood Diseases/Cure 4 the Kids Foundation Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Arkansas Children's Hospital Little Rock, Arkansas | |
| Arnold Palmer Hospital for Children Orlando, Florida | Site Public Contact - (Jennifer.spinelli@orlandohealth.com) |
| Ascension Saint Vincent Indianapolis Hospital Indianapolis, Indiana | Site Public Contact - (research@stvincent.org) |
| Atrium Health Navicent Macon, Georgia | Site Public Contact - (andrew.weatherall@atriumhealth.org) |
| Augusta University Medical Center Augusta, Georgia | Site Public Contact - (ga_cares@augusta.edu) |
| BI-LO Charities Children's Cancer Center Greenville, South Carolina | Site Public Contact - (Kim.Williams3@prismahealth.org) |
| Banner Children's at Desert Mesa, Arizona | |
| Banner University Medical Center - Tucson Tucson, Arizona | Site Public Contact - (UACC-IIT@uacc.arizona.edu) |
| Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center Houston, Texas | Site Public Contact - (burton@bcm.edu) |
| Baystate Medical Center Springfield, Massachusetts | Site Public Contact - (tamara.wrenn@baystatehealth.org) |
| Blank Children's Hospital Des Moines, Iowa | Site Public Contact - (samantha.mallory@unitypoint.org) |
| British Columbia Children's Hospital Vancouver, British Columbia | |
| Bronson Methodist Hospital Kalamazoo, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
| Broward Health Medical Center Fort Lauderdale, Florida | Site Public Contact - (Allison.bruce@nemours.org) |
| C S Mott Children's Hospital Ann Arbor, Michigan | |
| CHU de Quebec-Centre Hospitalier de l'Universite Laval (CHUL) Québec, | Site Public Contact - (rechclinique@crchudequebec.ulaval.ca) |
| CancerCare Manitoba Winnipeg, Manitoba | Site Public Contact - (ctu_web@cancercare.mb.ca) |
| Cardinal Glennon Children's Medical Center St Louis, Missouri | |
| Carilion Children's Roanoke, Virginia | Site Public Contact - (wpmccarty@carilionclinic.org) |
| Carolinas Medical Center/Levine Cancer Institute Charlotte, North Carolina | |
| Cedars Sinai Medical Center Los Angeles, California | |
| Centre Hospitalier Universitaire de Sherbrooke-Fleurimont Sherbrooke, Quebec | Site Public Contact - (crcinformation.chus@ssss.gouv.qc.ca) |
| Children's Healthcare of Atlanta - Arthur M Blank Hospital Atlanta, Georgia | Site Public Contact - (Olivia.Floyd@choa.org) |
| Children's Hospital London, Ontario | |
| Children's Hospital Colorado Aurora, Colorado | Site Public Contact - (josh.b.gordon@nsmtp.kp.org) |
| Children's Hospital Los Angeles Los Angeles, California | |
| Children's Hospital Medical Center Of Akron Akron, Ohio | |
| Children's Hospital New Orleans New Orleans, Louisiana | |
| Children's Hospital Of Eastern Ontario Ottawa, Ontario | |
| Children's Hospital and Medical Center of Omaha Omaha, Nebraska | |
| Children's Hospital of Alabama Birmingham, Alabama | Site Public Contact - (oncologyresearch@peds.uab.edu) |
| Children's Hospital of Michigan Detroit, Michigan | Site Public Contact - (helpdesk@childrensoncologygroup.org) |
| Children's Hospital of Orange County Orange, California | Site Public Contact - (oncresearch@choc.org) |
| Children's Hospital of Philadelphia Philadelphia, Pennsylvania | Site Public Contact - (CancerTrials@email.chop.edu) |
| Children's Hospital of Pittsburgh of UPMC Pittsburgh, Pennsylvania | Site Public Contact - (jean.tersak@chp.edu) |
| Children's Hospital of San Antonio San Antonio, Texas | Site Public Contact - (bridget.medina@christushealth.org) |
| Children's Hospital of Wisconsin Milwaukee, Wisconsin | Site Public Contact - (MACCCTO@mcw.edu) |
| Children's Hospital of the King's Daughters Norfolk, Virginia | Site Public Contact - (CCBDCresearch@chkd.org) |
| Children's Hospitals and Clinics of Minnesota - Minneapolis Minneapolis, Minnesota | Site Public Contact - (pauline.mitby@childrensmn.org) |
| Children's Mercy Hospitals and Clinics Kansas City, Missouri | Site Public Contact - (rryan@cmh.edu) |
| Children's National Medical Center Washington D.C., District of Columbia | Site Public Contact - (OncCRC_OnCall@childrensnational.org) |
| Christchurch Hospital Christchurch, | |
| Cincinnati Children's Hospital Medical Center Cincinnati, Ohio | Site Public Contact - (cancer@cchmc.org) |
| City of Hope Comprehensive Cancer Center Duarte, California | Site Public Contact - (becomingapatient@coh.org) |
| Cleveland Clinic Foundation Cleveland, Ohio | Site Public Contact - (TaussigResearch@ccf.org) |
| Connecticut Children's Medical Center Hartford, Connecticut | |
| Cook Children's Medical Center Fort Worth, Texas | Site Public Contact - (CookChildrensResearch@cookchildrens.org) |
| Corewell Health Children's Royal Oak, Michigan | |
| Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital Grand Rapids, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
| Covenant Children's Hospital Lubbock, Texas | Site Public Contact - (mbisbee@providence.org) |
| Dana-Farber Cancer Institute Boston, Massachusetts | |
| Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center Lebanon, New Hampshire | Site Public Contact - (cancer.research.nurse@dartmouth.edu) |
| Dayton Children's Hospital Dayton, Ohio | |
| Dell Children's Medical Center of Central Texas Austin, Texas | Site Public Contact - (TXAUS-DL-SFCHemonc.research@ascension.org) |
| Driscoll Children's Hospital Corpus Christi, Texas | Site Public Contact - (Crystal.DeLosSantos@dchstx.org) |
| Duke University Medical Center Durham, North Carolina | |
| East Carolina University Greenville, North Carolina | Site Public Contact - (eubankss@ecu.edu) |
| East Tennessee Childrens Hospital Knoxville, Tennessee | |
| Eastern Maine Medical Center Bangor, Maine | |
| Edwards Comprehensive Cancer Center Huntington, West Virginia | |
| El Paso Children's Hospital El Paso, Texas | Site Public Contact - (ranjan.bista@ttuhsc.edu) |
| Geisinger Medical Center Danville, Pennsylvania | Site Public Contact - (HemonCCTrials@geisinger.edu) |
| Golisano Children's Hospital of Southwest Florida Fort Myers, Florida | Site Public Contact - (molly.arnstrom@leehealth.org) |
| HIMA San Pablo Oncologic Hospital Caguas, | |
| Hackensack University Medical Center Hackensack, New Jersey | |
| Henry Ford Health Saint John Hospital Detroit, Michigan | |
| Hospital for Sick Children Toronto, Ontario | Site Public Contact - (ask.CRS@sickkids.ca) |
| IWK Health Centre Halifax, Nova Scotia | Site Public Contact - (Research@iwk.nshealth.ca) |
| Inova Fairfax Hospital Falls Church, Virginia | Site Public Contact - (Stephanie.VanBebber@inova.org) |
| Janeway Child Health Centre St. John's, Newfoundland and Labrador | Site Public Contact - (beverlyj.mitchell@easternhealth.ca) |
| Jersey Shore Medical Center Neptune City, New Jersey | |
| Jim Pattison Children's Hospital Saskatoon, Saskatchewan | Site Public Contact - (Jessica.Marien@saskhealthauthority.ca) |
| John Hunter Children's Hospital Hunter Regional Mail Centre, New South Wales | |
| Johns Hopkins All Children's Hospital St. Petersburg, Florida | Site Public Contact - (Ashley.Repp@jhmi.edu) |
| Johns Hopkins University/Sidney Kimmel Cancer Center Baltimore, Maryland | Site Public Contact - (jhcccro@jhmi.edu) |
| Kaiser Permanente Downey Medical Center Downey, California | |
| Kaiser Permanente-Oakland Oakland, California | Site Public Contact - (Kpoct@kp.org) |
| Kapiolani Medical Center for Women and Children Honolulu, Hawaii | |
| Kingston Health Sciences Centre Kingston, Ontario | Site Public Contact - (cc-clinicaltrials@kgh.kari.net) |
| Laura and Isaac Perlmutter Cancer Center at NYU Langone New York, New York | Site Public Contact - (CancerTrials@nyulangone.org) |
| Legacy Emanuel Children's Hospital Portland, Oregon | |
| Lehigh Valley Hospital-Cedar Crest Allentown, Pennsylvania | Site Public Contact - (Morgan_M.Horton@lvhn.org) |
| Loma Linda University Medical Center Loma Linda, California | |
| Loyola University Medical Center Maywood, Illinois | |
| Lucile Packard Children's Hospital Stanford University Palo Alto, California | Site Public Contact - (ccto-office@stanford.edu) |
| Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center Torrance, California | |
| Lurie Children's Hospital-Chicago Chicago, Illinois | |
| M D Anderson Cancer Center Houston, Texas | Site Public Contact - (askmdanderson@mdanderson.org) |
| Madigan Army Medical Center Tacoma, Washington | |
| Maimonides Medical Center Brooklyn, New York | |
| Maine Children's Cancer Program Scarborough, Maine | Site Public Contact - (clinicalresearch@mainehealth.org) |
| Marshfield Medical Center-Marshfield Marshfield, Wisconsin | |
| Mary Bridge Children's Hospital and Health Center Tacoma, Washington | Site Public Contact - (research@multicare.org) |
| Massachusetts General Hospital Cancer Center Boston, Massachusetts | |
| Mattel Children's Hospital UCLA Los Angeles, California | |
| Mayo Clinic in Rochester Rochester, Minnesota | |
| McMaster Children's Hospital at Hamilton Health Sciences Hamilton, Ontario | |
| MedStar Georgetown University Hospital Washington D.C., District of Columbia | |
| Medical City Dallas Hospital Dallas, Texas | |
| Medical University of South Carolina Charleston, South Carolina | Site Public Contact - (hcc-clinical-trials@musc.edu) |
| Memorial Health University Medical Center Savannah, Georgia | Site Public Contact - (Lorraine.OHara@hcahealthcare.com) |
| Memorial Regional Hospital/Joe DiMaggio Children's Hospital Hollywood, Florida | Site Public Contact - (OHR@mhs.net) |
| Memorial Sloan Kettering Cancer Center New York, New York | |
| Mercy Hospital Saint Louis St Louis, Missouri | |
| Methodist Children's Hospital of South Texas San Antonio, Texas | Site Public Contact - (Vinod.GidvaniDiaz@hcahealthcare.com) |
| Miami Cancer Institute Miami, Florida | |
| Michigan State University East Lansing, Michigan | |
| Miller Children's and Women's Hospital Long Beach Long Beach, California | |
| Mission Hospital Asheville, North Carolina | Site Public Contact - (NCDV.ResearchRegulatory@HCAHealthcare.com) |
| Monash Medical Center-Clayton Campus Clayton, Victoria | |
| Montefiore Medical Center - Moses Campus The Bronx, New York | Site Public Contact - (eskwak@montefiore.org) |
| Morristown Medical Center Morristown, New Jersey | |
| Mount Sinai Hospital New York, New York | Site Public Contact - (CCTO@mssm.edu) |
| NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center New York, New York | Site Public Contact - (cancerclinicaltrials@cumc.columbia.edu) |
| NYP/Weill Cornell Medical Center New York, New York | |
| NYU Langone Hospital - Long Island Mineola, New York | Site Public Contact - (cancertrials@nyulangone.org) |
| Natalie Warren Bryant Cancer Center at Saint Francis Tulsa, Oklahoma | |
| Nationwide Children's Hospital Columbus, Ohio | Site Public Contact - (Melinda.Triplet@nationwidechildrens.org) |
| Naval Medical Center - Portsmouth Portsmouth, Virginia | |
| Naval Medical Center -San Diego San Diego, California | |
| Nemours Children's Clinic - Pensacola Pensacola, Florida | Site Public Contact - (helpdesk@childrensoncologygroup.org) |
| Nemours Children's Clinic-Jacksonville Jacksonville, Florida | Site Public Contact - (Allison.bruce@nemours.org) |
| Nemours Children's Hospital Orlando, Florida | Site Public Contact - (Allison.bruce@nemours.org) |
| New York Medical College Valhalla, New York | |
| Newark Beth Israel Medical Center Newark, New Jersey | Site Public Contact - (Christine.Kosmides@rwjbh.org) |
| Nicklaus Children's Hospital Miami, Florida | |
| Northwestern Medicine Central DuPage Hospital Winfield, Illinois | Site Public Contact - (Claudine.Gamster@CadenceHealth.org) |
| Norton Children's Hospital Louisville, Kentucky | Site Public Contact - (CancerResource@nortonhealthcare.org) |
| Novant Health Presbyterian Medical Center Charlotte, North Carolina | Site Public Contact - (kashah@novanthealth.org) |
| Ochsner Medical Center Jefferson New Orleans, Louisiana | Site Public Contact - (Elisemarie.curry@ochsner.org) |
| Oregon Health and Science University Portland, Oregon | Site Public Contact - (trials@ohsu.edu) |
| Palms West Radiation Therapy Loxahatchee Groves, Florida | |
| Penn State Children's Hospital Hershey, Pennsylvania | |
| Perth Children's Hospital Perth, Western Australia | Site Public Contact - (helpdesk@childrensoncologygroup.org) |
| Phoenix Childrens Hospital Phoenix, Arizona | |
| Presbyterian Hospital Albuquerque, New Mexico | Site Public Contact - (wburman@phs.org) |
| Primary Children's Hospital Salt Lake City, Utah | |
| Prisma Health Richland Hospital Columbia, South Carolina | Site Public Contact - (Kim.Williams3@prismahealth.org) |
| ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital Toledo, Ohio | Site Public Contact - (PCIOncResearch@promedica.org) |
| Providence Alaska Medical Center Anchorage, Alaska | Site Public Contact - (AKPAMC.OncologyResearchSupport@providence.org) |
| Providence Sacred Heart Medical Center and Children's Hospital Spokane, Washington | Site Public Contact - (HopeBeginsHere@providence.org) |
| Queensland Children's Hospital South Brisbane, Queensland | |
| Rady Children's Hospital - San Diego San Diego, California | |
| Rainbow Babies and Childrens Hospital Cleveland, Ohio | |
| Renown Regional Medical Center Reno, Nevada | Site Public Contact - (research@sncrf.org) |
| Rhode Island Hospital Providence, Rhode Island | |
| Riley Hospital for Children Indianapolis, Indiana | |
| Rocky Mountain Hospital for Children-Presbyterian Saint Luke's Medical Center Denver, Colorado | Site Public Contact - (PSGResearchSharedMailbox@HCAHealthcare.com) |
| Roswell Park Cancer Institute Buffalo, New York | Site Public Contact - (askroswell@roswellpark.org) |
| Royal Children's Hospital Parkville, Victoria | Site Public Contact - (Jordan.Hansford@rch.org.au) |
| Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital New Brunswick, New Jersey | |
| Sacred Heart Hospital Pensacola, Florida | |
| Saint Christopher's Hospital for Children Philadelphia, Pennsylvania | |
| Saint Joseph's Hospital/Children's Hospital-Tampa Tampa, Florida | Site Public Contact - (jennifer.manns@baycare.org) |
| Saint Joseph's Regional Medical Center Paterson, New Jersey | Site Public Contact - (HallL@sjhmc.org) |
| Saint Jude Midwest Affiliate Peoria, Illinois | |
| Saint Luke's Cancer Institute - Boise Boise, Idaho | Site Public Contact - (eslinget@slhs.org) |
| Saint Mary's Medical Center West Palm Beach, Florida | |
| Saint Peter's University Hospital New Brunswick, New Jersey | Site Public Contact - (kcovert@saintpetersuh.com) |
| Saint Vincent Hospital Cancer Center Green Bay Green Bay, Wisconsin | Site Public Contact - (WI_research_admin@hshs.org) |
| Sanford Broadway Medical Center Fargo, North Dakota | Site Public Contact - (OncologyClinicalTrialsFargo@sanfordhealth.org) |
| Sanford USD Medical Center - Sioux Falls Sioux Falls, South Dakota | Site Public Contact - (OncologyClinicalTrialsSF@SanfordHealth.org) |
| Santa Barbara Cottage Hospital Santa Barbara, California | |
| Saskatoon Cancer Centre Saskatoon, Saskatchewan | |
| Scott and White Memorial Hospital Temple, Texas | |
| Seattle Children's Hospital Seattle, Washington | |
| Sinai Hospital of Baltimore Baltimore, Maryland | |
| Southern Illinois University School of Medicine Springfield, Illinois | |
| Starship Children's Hospital Grafton, Auckland | |
| State University of New York Upstate Medical University Syracuse, New York | |
| Stony Brook University Medical Center Stony Brook, New York | |
| Summerlin Hospital Medical Center Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Sunrise Hospital and Medical Center Las Vegas, Nevada | |
| Sutter Medical Center Sacramento Sacramento, California | |
| T C Thompson Children's Hospital Chattanooga, Tennessee | |
| Tampa General Hospital Tampa, Florida | Site Public Contact - (syapchanyk@tgh.org) |
| Texas Tech University Health Sciences Center-Amarillo Amarillo, Texas | |
| The Children's Hospital at TriStar Centennial Nashville, Tennessee | |
| The Children's Hospital at Westmead Westmead, New South Wales | |
| The Montreal Children's Hospital of the MUHC Montreal, Quebec | Site Public Contact - (info@thechildren.com) |
| The Steven and Alexandra Cohen Children's Medical Center of New York New Hyde Park, New York | |
| Tufts Children's Hospital Boston, Massachusetts | |
| UCSF Benioff Children's Hospital Oakland Oakland, California | Site Public Contact - (cogbchoak@ucsf.edu) |
| UCSF Medical Center-Mission Bay San Francisco, California | Site Public Contact - (cancertrials@ucsf.edu) |
| UMC Cancer Center / UMC Health System Lubbock, Texas | |
| UMass Memorial Medical Center - University Campus Worcester, Massachusetts | Site Public Contact - (cancer.research@umassmed.edu) |
| UNC Lineberger Comprehensive Cancer Center Chapel Hill, North Carolina | Site Public Contact - (cancerclinicaltrials@med.unc.edu) |
| USA Health Strada Patient Care Center Mobile, Alabama | |
| UT Southwestern/Simmons Cancer Center-Dallas Dallas, Texas | Site Public Contact - (canceranswerline@UTSouthwestern.edu) |
| University Medical Center of Southern Nevada Las Vegas, Nevada | |
| University Pediatric Hospital San Juan, | |
| University of Alberta Hospital Edmonton, Alberta | Site Public Contact - (pedsoncologyresearch@ahs.ca) |
| University of California Davis Comprehensive Cancer Center Sacramento, California | |
| University of Chicago Comprehensive Cancer Center Chicago, Illinois | Site Public Contact - (cancerclinicaltrials@bsd.uchicago.edu) |
| University of Florida Health Science Center - Gainesville Gainesville, Florida | Site Public Contact - (cancer-center@ufl.edu) |
| University of Illinois Chicago, Illinois | |
| University of Iowa/Holden Comprehensive Cancer Center Iowa City, Iowa | |
| University of Kentucky/Markey Cancer Center Lexington, Kentucky | |
| University of Maryland/Greenebaum Cancer Center Baltimore, Maryland | |
| University of Miami Miller School of Medicine-Sylvester Cancer Center Miami, Florida | |
| University of Minnesota/Masonic Cancer Center Minneapolis, Minnesota | |
| University of Mississippi Medical Center Jackson, Mississippi | |
| University of Missouri Children's Hospital Columbia, Missouri | Site Public Contact - (snwq62@health.missouri.edu) |
| University of Nebraska Medical Center Omaha, Nebraska | Site Public Contact - (unmcrsa@unmc.edu) |
| University of New Mexico Cancer Center Albuquerque, New Mexico | Site Public Contact - (HSC-ClinicalTrialInfo@salud.unm.edu) |
| University of Oklahoma Health Sciences Center Oklahoma City, Oklahoma | Site Public Contact - (ou-clinical-trials@ouhsc.edu) |
| University of Rochester Rochester, New York | |
| University of Texas Health Science Center at San Antonio San Antonio, Texas | Site Public Contact - (phoresearchoffice@uthscsa.edu) |
| University of Vermont and State Agricultural College Burlington, Vermont | Site Public Contact - (rpo@uvm.edu) |
| University of Virginia Cancer Center Charlottesville, Virginia | Site Public Contact - (uvacancertrials@hscmail.mcc.virginia.edu) |
| University of Wisconsin Carbone Cancer Center - University Hospital Madison, Wisconsin | Site Public Contact - (clinicaltrials@cancer.wisc.edu) |
| VCU Massey Comprehensive Cancer Center Richmond, Virginia | Site Public Contact - (CTOclinops@vcu.edu) |
| Valley Children's Hospital Madera, California | Site Public Contact - (Research@valleychildrens.org) |
| Vanderbilt University/Ingram Cancer Center Nashville, Tennessee | |
| Vannie Cook Children's Clinic McAllen, Texas | |
| Wake Forest University Health Sciences Winston-Salem, North Carolina | |
| Walter Reed National Military Medical Center Bethesda, Maryland | |
| Washington University School of Medicine St Louis, Missouri | Site Public Contact - (info@siteman.wustl.edu) |
| Wesley Medical Center Wichita, Kansas | Site Public Contact - (WesleyResearch@wesleymc.com) |
| West Virginia University Charleston Division Charleston, West Virginia | |
| West Virginia University Healthcare Morgantown, West Virginia | |
| Women's and Children's Hospital-Adelaide North Adelaide, South Australia | |
| Yale University New Haven, Connecticut | Site Public Contact - (canceranswers@yale.edu) |
Multi-level Factors Related to Cancer Incidence and Mortality in Virginia
Do, Elizabeth - elizabeth.do@vcuhealth.org
Fuemmeler, Bernard
14583
HM20013845
Any Site
I'm interested
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Do, Elizabeth - (elizabeth.do@vcuhealth.org) |
Caring and Coping with Cancer (C3) (C3)
Winter, Marcia - mawinter@vcu.edu
Winter, Marcia
N/A
14620
HM20014307
Lymphoid Leukemia, Multiple Myeloma, Myeloid and Monocytic Leukemia, Non-Hodgkin's Lymphoma
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Winter, Marcia - (mawinter@vcu.edu) |
Expanded Access of Obinutuzumab in a Patient Who Responded to Treatment While on a Clinical Trial
ctrrecruit@vcu.edu
Yazbeck, Victor, Y
N/A
14756
HM20015975
drug: Obinutuzumab, Modality: Chemotherapy (nos)
Non-Hodgkin's Lymphoma
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia |
Engaging Male Cancer Survivors in Rural Virginia
Cummings, Yvonne - yvonne.cummings@vcuhealth.org
Preston, Michael
N/A
14847
HM20014377
Prostate, Rectum, Colon
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Cummings, Yvonne - (yvonne.cummings@vcuhealth.org) |
Together For Health - Virginia
Sheng, Yaou - yaou.sheng@vcuhealth.org
Fuemmeler, Bernard
N/A
14539
HM20014823
I'm interested
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|---|---|
| Virginia Commonwealth University Richmond, Virginia | Sheng, Yaou - (yaou.sheng@vcuhealth.org) |
Perception of Surgery, Chemotherapy and Radiotherapy Among Different Groups
Smallfield, George, B - gbsmallfield@vcu.edu
Smallfield, George, B
N/A
15419
HM20016811
Esophagus
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Smallfield, George, B - (gbsmallfield@vcu.edu) |
Virginia Commonwealth University Registry of SARS-CoV-2 (VCU-RS)
Namoos, Asmaa - asmaa.namoos@vcuhealth.org
Albhaisi, Somaya
N/A
16462
HM20019224
Infectious and Parasitic Diseases (001-139)
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|---|---|
| Virginia Commonwealth University Richmond, Virginia | Namoos, Asmaa - (asmaa.namoos@vcuhealth.org) |
National COVID Cohort Collaborative (N3C): A National Resource for Shared Analytics
ctrrecruit@vcu.edu
Gal, Tamas
N/A
16821
HM20019575
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|---|---|
| Virginia Commonwealth University Richmond, Virginia |
COVID-19 and Kidney Transplant Recipients - Clinical Course and Serologies
ctrrecruit@vcu.edu
Kumar, Dhiren
Pilot
16840
HM20019491
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia |