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642 Study Matches
Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT
Suna Chung, MPH - schung60@jhu.edu
Kates, Stephen, L
NCT04678154
HM20022236
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Inclusion Criteria:
• Injury meeting at least one of the following criteria: * Gustilo type III tibia (OTA 41 plateau, OTA 42 shaft and OTA 43 pilon) requiring a second procedure for final debridement and definitive coverage / closure following the index stabilization * Gustilo type IIIB ankle fractures (OTA 44) * Gustilo type IIIB calcaneus fractures (OTA 82) * Gustilo type IIIB talus fractures (OTA 81) * Traumatic "zone-of-injury" trans-tibial amputations requiring DPC, and/or flap coverage
• Ages 18 - 64 years inclusive
• Patients may have risk factors for infection including diabetes, immunosuppression from steroids or other medications, HIV, or other infections.
• Patients may have a traumatic brain injury.
• Patients may have other fractures including spine, upper extremity fractures, contralateral lower extremity injuries, ipsilateral pelvis, hip, femur or foot injuries.
• Patients may be treated initially at an outside institution prior to transfer to the study institution, as long as the definitive wound closure or coverage was not performed prior to entrance into the study.
• Patients with bilateral injuries that meet inclusion criteria may be included, but only the limb rated as "more severe" by the treating surgeon will be enrolled in the study.
• Patients may have co-existing non-tibial or hindfoot infection, with or without antibiotic treatment.
• Patients may be definitively stabilized using any method (nail, plate, ex fix or cast).
• Patients may have a fasciotomy.
Exclusion Criteria:
• Patient in current therapy for a wound, implant or fracture site infection related to the study site.
• Patient likely to have difficulty maintaining follow-up, including: * Diagnosis of a severe psychiatric condition * Intellectually challenged without adequate family support * Resides outside of the hospital's catchment area * Planning to follow-up at another medical center * Being a prisoner * Not having a means of contact (address, cell phone, home phone, e-mail)
DRUG: Standard of care, DRUG: Vancomycin and Tobramycin
Post Operative Surgical Site Infection
Surgical site infection risk prevention, Bacterial species type and antibacterial sensitivities
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| Location | Contacts |
|---|---|
| Atrium Health Carolinas Medical Center Charlotte, North Carolina | |
| Atrium Health Wake Forest Baptist Charlotte, North Carolina | Martha Holden - (mholden@wakehealth.edu) |
| Brown University/Rhode Island Hospital Providence, Rhode Island | |
| Dartmouth Hitchcock Lebanon, New Hampshire | Devin Mullin - (devin.s.mullin@hitchcock.org) |
| Emory University School Of Medicine Atlanta, Georgia | |
| Harvard/Mass General/Brigham Hospitals Boston, Massachusetts | Thiru Wignakumar - (twignakumar@bwh.harvard.edu) |
| Hennepin County Medical Center / Minneapolis Minneapolis, Minnesota | |
| Indiana University School of Medicine - Methodist Hospital Indianapolis, Indiana | Maricella Diaz - (diaz4@iu.edu) |
| Indiana University/Eskenazi Health Indianapolis, Indiana | Molly Moore - (momfreed@iupui.edu) |
| Inova Fairfax Medical Campus Falls Church, Virginia | Senay Ghidei - (Senay.Ghidei@Inova.org) |
| Jamaica Hospital Medical Center Jamaica, New York | |
| LSU Health Sciences New Orleans, Louisiana | Jessica Rivera - (jrive5@lsuhsc.edu) |
| MetroHealth Cleveland, Ohio | Anna Vergon - (avergon@metrohealth.org) |
| Ohio State University Wexner Medical Center Columbus, Ohio | Jessica Wiseman - (jessica.wiseman@osumc.edu) |
| Rhode Island Hospital/Brown University Providence, Rhode Island | MJ Crisco - (mjcrisco@uoi.com) |
| St Mary's University/Tenent Health West Palm Beach, Florida | Tracy Rodriguez - (tracy.rodriguez@tenethealth.com) |
| Stanford University Stanford, California | Carina Tedesco - (ctedesco@stanford.edu) |
| Temple University Philadelphia, Pennsylvania | Adam Lloyd-Jones - (adam.lloyd-jones@temple.edu) |
| University of California at San Francisco San Francisco, California | Eleni Berhaneselase - (Eleni.Berhaneselase@ucsf.edu) |
| University of Colorado Anschutz Medical Campus Aurora, Colorado | Fahim Choudhury - (fahim.choudhury@cuanschutz.edu) |
| University of Kentucky Lexington, Kentucky | Matthew Eubank - (mseuba01@uky.edu) |
| University of Maryland , MD Department of Orthopaedics Baltimore, Maryland | Yasmin Degani, MPH - (ydegani@som.umaryland.edu) |
| University of Mississippi Medical Center Jackson, Mississippi | Sandra Powe - (spowe@umc.edu) |
| University of North Carolina at Chapel Hill Chapel Hill, North Carolina | Nevaeh Nez - (nevaeh_nez@med.unc.edu) |
| University of Oklahoma College of Medicine Oklahoma City, Oklahoma | Lyndee Nguyen - (lyndee-nguyen@ouhsc.edu) |
| University of Texas Health Science Center - Houston Houston, Texas | Sterling Boutte - (Sterling.Boutte@uth.tmc.edu) |
| University of Virginia Charlottesville, Virginia | Eric McVey - (EDM9U@hscmail.mcc.virginia.edu) |
| Vanderbilt University Medical Center Nashville, Tennessee | Karen Trochez - (karen.m.trochez@Vanderbilt.Edu) |
| Virginia Commonwealth University Medical Center Richmond, Virginia | Caleb Bridgman - (Caleb.Bridgwater@vcuhealth.org) |
| Walter Reed Military Medical Center Bethesda, Maryland | Heather Decot - (heather.k.decot.ctr@health.mil) |
| _University of California, San Francisco San Francisco, California | Eleni Berhaneselase - (eleni.berhaneselase@ucsf.edu) |
Observational - Characteristics, Treatment, Outcomes -Severe Asthma in the US (CHRONICLE)
Toft, Robin - robin.toft@vcuhealth.org
Mohan, Arjun
NCT03373045
HM20022693
Modality: No vcuhs billing
Diseases of Respiratory System (460-519)
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Toft, Robin - (robin.toft@vcuhealth.org) |
Efficacy/Safety SPR001 (Tildacerfont) Reducing Supraphysiologic Glucocorticoid Use in Adults w CAH
Memoli, Erica, H - erica.memoli@vcuhealth.org
Gupta, Anshu
NCT04544410
HM20019420
drug: Spr001 (tildacerfont)
Endocrine, Nutritional, Metabolic Diseases, Immunity Disorders (240-279)
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Memoli, Erica, H - (erica.memoli@vcuhealth.org) |
Efficacy/Safety of SPR001 (Tildacerfont) in Adults with Classic Congenital Adrenal Hyperplasia
Memoli, Erica, H - erica.memoli@vcuhealth.org
Gupta, Anshu
NCT04457336
HM20019413
drug: Spr001 (tildacerfont)
Endocrine, Nutritional, Metabolic Diseases, Immunity Disorders (240-279)
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Memoli, Erica, H - (erica.memoli@vcuhealth.org) |
Efficacy of EsoGuard on Samples Collected Using EsoCheck Versus EGD for the Diagnosis of BE
Coleman, PARIS - paris.coleman@vcuhealth.org
Smallfield, George, B
NCT04293458
HM20018839
Diseases of Digestive System (520-579)
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Coleman, PARIS - (paris.coleman@vcuhealth.org) |
Phase Ib/II of ARRY-614 plus either nivolumab or nivolumab+ipilimumab in advanced solid tumors
Osipova, Ekaterina - osipovak@vcu.edu
Poklepovic, Andrew, S
NCT04074967
HM20021810
drug: Nivolumab,
drug: Ipilimumab,
drug: Arry-614, Modality: Immunotherapy
Melanoma, skin, Other Urinary, Urinary Bladder, Thyroid, Stomach, Soft Tissue, Small Intestine, Rectum, Prostate, Pancreas, Ovary, Other Respiratory and Intrathoracic Organs, Other Male Genital, Other Female Genital, Other Endocrine System, Other Digestive Organ, Lung, Liver, Lip, Oral Cavity and Pharynx, Larynx, Kidney, Eye and Orbit, Ill-Defined Sites, Esophagus, Corpus Uteri, Colon, Cervix, Breast, Brain and Nervous System, Bones and Joints
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Osipova, Ekaterina - (osipovak@vcu.edu) |
A Study to Assess the Efficacy and Safety of VK2809 for 52 Weeks in Subjects With Biopsy Proven NASH (VOYAGE)
Hurst, Caitlin - hurstc3@vcu.edu
Sanyal, Arun, J
NCT04173065
HM20018948
drug: Vk2809
Diseases of Digestive System (520-579)
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Hurst, Caitlin - (hurstc3@vcu.edu) |
Efficacy, Safety, and Tolerability of Efgartigimod PH20 SC in Adult with CIDP (ADHERE)
Smith, LaVon - lavon.smith@vcuhealth.org
Gwathmey, Kelly
NCT04281472
HM20018410
drug: Argx-113
Diseases of Nervous System and Sense Organs (320-389)
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Smith, LaVon - (lavon.smith@vcuhealth.org) |
The Effect of Electronic Cigarette Liquid Characteristics in Smokers.
Breland, Alison - abbrelan@vcu.edu
Eissenberg, Thomas, E
NCT03861078
HM20015258
Lung
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Breland, Alison - (abbrelan@vcu.edu) |
Safety Study of Etripamil Nasal Spray for Patients With Paroxysmal Supraventricular Tachycardia
Sami, Aysha, V - Aysha.Sami@vcuhealth.org
Ellenbogen, Kenneth, A
NCT04072835
HM20018724
drug: Etripamil
Diseases of Circulatory System (390-459)
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Sami, Aysha, V - (Aysha.Sami@vcuhealth.org) |
Improving Communication and Adherence in Black Breast Cancer Survivors (SIS) (SISTERS)
Cummings, Yvonne - yvonne.cummings@vcuhealth.org
Sheppard, Vanessa, B.
NCT05334732
HM20016396
Breast
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Cummings, Yvonne - (yvonne.cummings@vcuhealth.org) |
Efficacy and Safety of Benralizumab vs Mepolizumab in Treatment of EGPA (MANDARA) (MANDARA)
ctrrecruit@vcu.edu
Ward, Brant
NCT04157348
HM20018295
drug: Mepolizumab,
drug: Benralizumab
Diseases of Circulatory System (390-459)
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia |
A Clinical Study to Evaluate the Efficacy and Safety of Aramchol in Subjects With NASH (ARMOR)
Lindemuth, Margaret (Maggie) - margaret.lindemuth@vcuhealth.org
Siddiqui, Mohammad, S
NCT04104321
HM20018490
drug: Aramchol
Diseases of Digestive System (520-579)
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Lindemuth, Margaret (Maggie) - (margaret.lindemuth@vcuhealth.org) |
Comparison of Surgery and Medicine on the Impact of Diverticulitis (COSMID) Trial (COSMID)
Kelsey M Pullar, MPH - kpullar@uw.edu
Wieghard, Nicole
NCT04095663
HM20016794
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Inclusion Criteria:
* Adults ≥18 years
* At least one episode of diverticulitis confirmed by CT scan and a colonoscopy (completed or scheduled) to rule out or screen for other colon pathology in accordance with colorectal cancer screening guidelines
* Persistent signs, symptoms, or concerns related to diverticulitis after recovery from an episode of left-sided diverticulitis
* Self-reported QoL limitation (assessed with 12 questions modified from the Diverticulitis Quality of Life \[DV-QOL\] instrument).
Exclusion Criteria:
* Unable to consent in English or Spanish
* Current diagnosis or previous endoscopic or surgical interventions for fistula, or stricture or current significant bleeding, related to diverticulitis
* Last episode of acute diverticulitis currently unresolved (i.e., on antibiotics for diverticulitis; drain in place)
* Previous operation for diverticulitis
* Right-sided diverticulitis
* Immunodeficiency (e.g., absolute neutrophil count \<500/mm3, chronic immunosuppressive drugs like oral corticosteroids, anti-TNF agents, or known AIDS \[i.e., recent CD4 count \<200\] assessed by patient history)
* Actively undergoing chemotherapy or radiation for malignancy
* Expectant or concurrent hemodialysis, peritoneal dialysis, treatments using indwelling venous catheters, or conditions putting patient at risk for bacterial seeding
* Diagnosis of inflammatory bowel disease (i.e., Crohn's, ulcerative colitis)
* Taking prescription medication for irritable bowel syndrome
* Intolerance or allergy to all medications in the medical management arm
* Surgeon is unwilling to offer surgery due to comorbid or prior surgical conditions that contraindicate elective surgery (e.g., liver failure, renal failure, malignancy, "frozen abdomen")
* Abdominal/pelvic surgery within the past month
* Pregnant or expecting to become pregnant in the 30 days following baseline/screening
* Unable to consent to research or self-respond to follow-up surveys (e.g., altered mental status)
* Currently incarcerated in a detention facility or in police custody at baseline/screening (patients wearing a monitoring device can be enrolled)
* Prior enrollment in the COSMID study or planning on enrollment in another investigational drug or vaccine while on study treatment
* Unable or unwilling to return, be contacted for, or complete research surveys. PROCEDURE: Partial Colectomy, OTHER: Medical Management
Diverticulitis
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| Location | Contacts |
|---|---|
| Albany Medical College Albany, New York | |
| Allegheny-Singer Research Institute Pittsburgh, Pennsylvania | Rachel Reading - (rachel.reading@ahn.org) |
| Atrium Health-Carolinas Medical Center Charlotte, North Carolina | Colie Kaiser - (nicole.kaiser@atriumhealth.org) |
| Benaroya Research Institute at Virginia Mason Seattle, Washington | Audrey Merz - (Audrey.Merz@virginiamason.org) |
| Boston University Medical Center Boston, Massachusetts | Marina Malikova - (Marina.Malikova@bmc.org) |
| Cedars-Sinai Medical Center Los Angeles, California | |
| Columbia University Medical Center New York, New York | Ken Watanabe - (kw3145@cumc.columbia.edu) |
| Lahey Clinic Burlington, Massachusetts | Kameron Ky - (Kameron.ky@lahey.org) |
| Medical University of South Carolina Charleston, South Carolina | Natalie Koren - (korenn@musc.edu) |
| Memorial Health University Medical Center Savannah, Georgia | Anne Brooks - (anne.brooks@hcahealthcare.com) |
| Mount Carmel Health Systems Columbus, Ohio | Sheila Brooks - (sbrooks2@mchs.com) |
| New York Presbyterian-Queens Flushing, New York | Susan Ingenito - (sui9006@nyp.org) |
| Northwestern University Chicago, Illinois | Rose Arrieta - (rarrieta@northwestern.edu) |
| Penn Medicine Philadelphia, Pennsylvania | |
| Rush University Medical Center Chicago, Illinois | Matthew Johnson - (Matthew_johnson@rush.edu) |
| Stanford University Medical Center Palo Alto, California | Kristen Davis - (kdavis3@stanford.edu) |
| UC San Diego Health San Diego, California | |
| UCSF Health San Francisco, California | Jenny Broering - (Jenny.Broering@ucsf.edu) |
| UT Southwestern Medical Center Dallas, Texas | |
| UTHealth Houston Houston, Texas | Debbie Nguyen - (debbie.f.lew@uth.tmc.edu) |
| University of Colorado Aurora, Colorado | Tracey MacDermott - (Tracey.MacDermott@ucdenver.edu) |
| University of Florida Gainesville, Florida | Amber Bouton - (Amber.Bouton@surgery.ufl.edu) |
| University of Iowa Healthcare Iowa City, Iowa | Jessica Danielson - (jessica-danielson@uiowa.edu) |
| University of Rochester Medical Center Rochester, New York | I Marianetti - (Ila_Marianetti@URMC.Rochester.edu) |
| University of South Florida Tampa, Florida | Avennette Pinto - (apinto3@usf.edu) |
| University of Utah Health Salt Lake City, Utah | Jordan Esplin - (jordan.esplin@hsc.utah.edu) |
| University of Washington Seattle, Washington | Mariam Hantouli, MD - (hantouli@uw.edu) Kelsey Pullar, MPH - (kpullar@uw.edu) |
| VCU Medical Center Richmond, Virginia | Jinfeng Han - (jinfeng.han@vcuhealth.org) |
| Weill Cornell Medicine New York, New York | Jordan Augsburger - (joa7035@med.cornell.edu) |
Safety and Immunogenicity of GSK Meningococcal Group B Vaccine and 13-valent Pneumococcal Vaccine
Lessard, Margaret "Meg" - margaret.lessard@vcuhealth.org
Meloy, Linda
NCT03621670
HM20014721
drug: Rmenb+omv nz,
drug: Pcv13
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Lessard, Margaret "Meg" - (margaret.lessard@vcuhealth.org) |
DSC-MRI in Measuring Cerebral Blood Volume for Early Response to Bevacizumab in Recurrent GBM
Hess, Alison - ahess2@vcu.edu
Chen, Zhi-Jian
NCT03115333
HM20021895
Brain and Nervous System
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Hess, Alison - (ahess2@vcu.edu) |
Validating Cell-Based Assays for ABMR After Renal Transplantation (CBA ABMR)
Baldecchi, Mary - mary.baldecchi@vcuhealth.org
Gupta, Gaurav
NCT03916822
HM20019307
Diseases of Genitourinary System (580-629)
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Baldecchi, Mary - (mary.baldecchi@vcuhealth.org) |
Study of Aldafermin (NGM282) in Subjects With Compensated Cirrhosis (ALPINE 4) (ALPINE4)
Lindemuth, Margaret (Maggie) - margaret.lindemuth@vcuhealth.org
Siddiqui, Mohammad, S
NCT04210245
HM20019792
drug: Ngm282
Diseases of Digestive System (520-579)
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Lindemuth, Margaret (Maggie) - (margaret.lindemuth@vcuhealth.org) |
Flexible-Dose, Adjunctive Therapy Trial in Adults With Parkinson s Disease With Motor Fluctuations
Norris, Virginia "Ginger" - virginia.norris@vcuhealth.org
Cloud, Leslie
NCT04542499
HM20019622
drug: Tavapadon (cvl-751)
Diseases of Nervous System and Sense Organs (320-389)
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Norris, Virginia "Ginger" - (virginia.norris@vcuhealth.org) |
Phase II - Long-term Safety and Efficacy in Adults With CDIP (ADHERE+) (ADHERE+)
Smith, LaVon - lavon.smith@vcuhealth.org
Gwathmey, Kelly
NCT04280718
HM20018942
drug: Argx-113
Diseases of Nervous System and Sense Organs (320-389)
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Smith, LaVon - (lavon.smith@vcuhealth.org) |
Efgartigimod Expanded Access for Generalized Myasthenia Gravis
Wilkins, Bridget - bridget.wilkins@vcuhealth.org
Gwathmey, Kelly
NCT04777734
HM20022105
Diseases of Nervous System and Sense Organs (320-389)
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Wilkins, Bridget - (bridget.wilkins@vcuhealth.org) |
Long-Term Safety and Efficacy Outcomes - Previously Administered SHP607 -Extremely Premature Infants
Lessard, Margaret "Meg" - margaret.lessard@vcuhealth.org
Rozycki, Henry
NCT04506619
HM20022198
Certain Conditions Originating in the Perinatal Period (760-779)
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Lessard, Margaret "Meg" - (margaret.lessard@vcuhealth.org) |
Study in PD Patients With Dyskinesia With Combinations of JM-010 and Its Individual Components
Blackwell, Gina, M - gina.blackwell@vcuhealth.org
Cloud, Leslie
NCT04377945
HM20021757
drug: Jm-010,
drug: Buspirone,
drug: Zolmitriptan
Diseases of Nervous System and Sense Organs (320-389)
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Blackwell, Gina, M - (gina.blackwell@vcuhealth.org) |
Saroglitazar Magnesium for the Treatment of Nonalcoholic Steatohepatitis with Fibrosis
Patel, Falgun - falgun.patel@vcuhealth.org
Siddiqui, Mohammad, S
NCT05011305
HM20021644
drug: Saroglitazar magnesium
Diseases of Digestive System (520-579)
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Patel, Falgun - (falgun.patel@vcuhealth.org) |
Phase 2B, Randomized, Double-Blind, Placebo-Controlled - Safety/ Efficacy of Efruxifermin - NASH
Edwards, Megan, C - megan.edwards@vcuhealth.org
Siddiqui, Mohammad, S
NCT04767529
HM20021459
drug: Efruxifermin
Diseases of Digestive System (520-579)
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Edwards, Megan, C - (megan.edwards@vcuhealth.org) |
Open-label Trial in Parkinson s Disease
Norris, Virginia "Ginger" - virginia.norris@vcuhealth.org
Cloud, Leslie
NCT04760769
HM20020944
drug: Tavapadon (cvl-751)
Diseases of Nervous System and Sense Organs (320-389)
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Norris, Virginia "Ginger" - (virginia.norris@vcuhealth.org) |
Cognitive Support Technology for Postsecondary Students with Autism Spectrum Disorder
Inge, Katherine, J - kinge@vcu.edu
Inge, Katherine, J
NCT04980963
HM20019035
Mental Disorders (290-319)
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Inge, Katherine, J - (kinge@vcu.edu) |
Evaluating the Acute Effect of Vaping on Food Intake
ctrrecruit@vcu.edu
Cobb, Caroline
NCT04219189
HM20018382
Any Site
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia |
Testing the Use of the Usual Chemotherapy Before and After Surgery for Removable Pancreatic Cancer
Cristina R. Ferrone, MD - cferrone@mgh.harvard.edu
Fernandez, Leopoldo
NCT04340141
HM20023842
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Inclusion Criteria:
PRE-REGISTRATION:
* Pathology: Histologic or cytologic proof of pancreatic adenocarcinoma or adenosquamous carcinoma
* TNM Stage: Tx-4, N0-1, M0 (M0 disease does not include spread to distant lymph nodes and organs)
* Resectable Primary Tumor: Local radiographic reading must be consistent with resectable disease defined as the following on 1) arterial and venous phase contrast-enhanced abdominal/pelvic CT scan or abdominal/pelvic magnetic resonance imaging (MRI) scan and 2) chest CT:
* No involvement or abutment of the celiac artery, common hepatic artery, superior mesenteric artery, or replaced right hepatic artery (if applicable)
* Less than 180 degree interface between tumor and vessel wall of the portal vein or superior mesenteric vein, and patent portal vein/splenic vein confluence
* No evidence of metastatic disease
* Measurable disease or non-measurable disease o Non-measurable disease is defined as cytologic or histologic confirmation of adenocarcinoma of adenosquamous carcinoma by fine needle aspiration or core-biopsy of the pancreas without measurable disease by radiographic imaging
REGISTRATION:
* Confirmation of resectable disease by real-time central imaging review by the Alliance Imaging Core Lab at Imaging and Radiation Oncology Core (IROC) Ohio
* Determined to be appropriate candidate for curative-intent pancreatectomy by surgeon intending to perform the resection
* No prior radiation therapy, chemotherapy, targeted therapy, investigational therapy, or surgery for pancreatic cancer
* Not pregnant and not nursing, because this study involves an agent that has known genotoxic, mutagenic, and teratogenic effects.
* Therefore, for women of childbearing potential only, a negative pregnancy test done =\< 14 days prior to registration is required
* Eastern Cooperative Oncology Group (ECOG) performance status 0-1
* Total Neuropathy Score \< 2
* Absolute neutrophil count (ANC) \>= 1,500/uL
* Platelet count \>= 100,000/uL
* Total bilirubin =\< 1.5 x upper limit of normal (ULN) (If obstructive jaundice is present, then biliary drainage must be initiated and total bilirubin =\< 3.0)
* Creatinine =\< 1.5 x ULN OR calculated (Calc.) creatinine clearance \>= 30 mL/min (Calculated using the Cockcroft-Gault equation)
* No known Gilbert's Syndrome or known homozygosity for UGAT1A1\*28 polymorphism
* No comorbid conditions that would prohibit curative-intent pancreatectomy
* Chronic concomitant treatment with strong inhibitors of CYP3A4 is not allowed on this study. Patients on strong CYP3A4 inhibitors must discontinue the drug prior to registration
* Chronic concomitant treatment with strong inducers of CYP3A4 is not allowed on this study. Patients on strong CYP3A4 inducers must discontinue the drug prior to registration DRUG: Oxaliplatin, DRUG: Irinotecan Hydrochloride, DRUG: Leucovorin Calcium, DRUG: Fluorouracil, PROCEDURE: Resection, OTHER: Questionnaire Administration
Pancreatic Adenosquamous Carcinoma, Resectable Pancreatic Adenocarcinoma, Pancreatic Cancer
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Show 454 locations
Study Locations
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| Location | Contacts |
|---|---|
| Adams Cancer Center Gettysburg, Pennsylvania | |
| Adena Regional Medical Center Chillicothe, Ohio | |
| AdventHealth Altamonte Altamonte Springs, Florida | |
| AdventHealth Orlando Orlando, Florida | |
| AdventHealth Porter Denver, Colorado | |
| Alaska Breast Care and Surgery LLC Anchorage, Alaska | |
| Alaska Oncology and Hematology LLC Anchorage, Alaska | |
| Alaska Women's Cancer Care Anchorage, Alaska | |
| Allegheny General Hospital Pittsburgh, Pennsylvania | |
| Alta Bates Summit Medical Center-Herrick Campus Berkeley, California | |
| Anchorage Associates in Radiation Medicine Anchorage, Alaska | |
| Anchorage Oncology Centre Anchorage, Alaska | |
| Arthur J E Child Comprehensive Cancer Centre Calgary, Alberta | Site Public Contact - (ctsucontact@westat.com) |
| Ascension Columbia Saint Mary's Hospital - Milwaukee Milwaukee, Wisconsin | Site Public Contact - (AWRI.Inquiry@Ascension.org) |
| Ascension Columbia Saint Mary's Hospital Ozaukee Mequon, Wisconsin | Site Public Contact - (AWRI.Inquiry@Ascension.org) |
| Aspirus Cancer Care - Wisconsin Rapids Wisconsin Rapids, Wisconsin | |
| Aspirus Medford Hospital Medford, Wisconsin | |
| Aspirus Regional Cancer Center Wausau, Wisconsin | |
| Asplundh Cancer Pavilion Willow Grove, Pennsylvania | |
| Atrium Medical Center-Middletown Regional Hospital Franklin, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Augusta University Medical Center Augusta, Georgia | |
| Avera Cancer Institute Sioux Falls, South Dakota | |
| Avera Cancer Institute - Mitchell Mitchell, South Dakota | |
| Avera Cancer Institute at Pierre Pierre, South Dakota | |
| Avera Cancer Institute at Yankton Yankton, South Dakota | |
| Avera Cancer Institute-Aberdeen Aberdeen, South Dakota | |
| BCCA-Vancouver Cancer Centre Vancouver, British Columbia | |
| BCCA-Vancouver Island Cancer Centre Victoria, British Columbia | |
| BJC Outpatient Center at Sunset Hills Sunset Hills, Missouri | |
| Banner University Medical Center - Tucson Tucson, Arizona | |
| Baptist Cancer Center-Grenada Grenada, Mississippi | Site Public Contact - (BCCclintrials@bmhcc.org) |
| Baptist Health Lexington Lexington, Kentucky | |
| Baptist Health Louisville Louisville, Kentucky | |
| Baptist Health Madisonville/Merle Mahr Cancer Center Madisonville, Kentucky | |
| Baptist Memorial Hospital and Cancer Center-Collierville Collierville, Tennessee | Site Public Contact - (BCCclintrials@bmhcc.org) |
| Baptist Memorial Hospital and Cancer Center-Desoto Southhaven, Mississippi | Site Public Contact - (BCCclintrials@bmhcc.org) |
| Baptist Memorial Hospital and Cancer Center-Memphis Memphis, Tennessee | Site Public Contact - (BCCclintrials@bmhcc.org) |
| Baptist Memorial Hospital and Cancer Center-Oxford Oxford, Mississippi | Site Public Contact - (BCCclintrials@bmhcc.org) |
| Baptist Memorial Hospital and Cancer Center-Union County New Albany, Mississippi | Site Public Contact - (BCCclintrials@bmhcc.org) |
| Bay Area Hospital Coos Bay, Oregon | |
| Benefis Sletten Cancer Institute Great Falls, Montana | |
| Billings Clinic Cancer Center Billings, Montana | |
| Boston Medical Center Boston, Massachusetts | |
| Bozeman Health Deaconess Hospital Bozeman, Montana | |
| Broadlawns Medical Center Des Moines, Iowa | |
| CHU de Quebec-L'Hotel-Dieu de Quebec (HDQ) Québec, Quebec | Site Public Contact - (rechclinique@crchuq.ulaval.ca) |
| California Pacific Medical Center-Pacific Campus San Francisco, California | |
| Cancer Care Center of O'Fallon O'Fallon, Illinois | |
| Cancer Care Specialists of Illinois - Decatur Decatur, Illinois | |
| CancerCare Manitoba Winnipeg, Manitoba | Site Public Contact - (ctu_web@cancercare.mb.ca) |
| Carilion Roanoke Memorial Hospital Roanoke, Virginia | |
| Carle Cancer Center Urbana, Illinois | |
| Carle Physician Group-Effingham Effingham, Illinois | |
| Carle Physician Group-Mattoon/Charleston Mattoon, Illinois | |
| Carle at The Riverfront Danville, Illinois | |
| CarolinaEast Medical Center New Bern, North Carolina | Site Public Contact - (lharrison@carolinaeasthealth.com) |
| Carolinas Medical Center/Levine Cancer Institute Charlotte, North Carolina | |
| Case Western Reserve University Cleveland, Ohio | Site Public Contact - (CTUReferral@UHhospitals.org) |
| Cedars Sinai Medical Center Los Angeles, California | |
| Centralia Oncology Clinic Centralia, Illinois | |
| Centre Hospitalier Universitaire de Sherbrooke-Fleurimont Sherbrooke, Quebec | Site Public Contact - (crcinformation.chus@ssss.gouv.qc.ca) |
| Chelsea Hospital Chelsea, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Clackamas Radiation Oncology Center Clackamas, Oregon | |
| Cleveland Clinic Akron General Akron, Ohio | Site Public Contact - (CancerAnswer@ccf.org) |
| Cleveland Clinic Cancer Center Mansfield Mansfield, Ohio | |
| Cleveland Clinic Cancer Center/Fairview Hospital Cleveland, Ohio | |
| Cleveland Clinic Foundation Cleveland, Ohio | |
| Cleveland Clinic Wooster Family Health and Surgery Center Wooster, Ohio | |
| Cleveland Clinic-Weston Weston, Florida | |
| Community Cancer Institute Clovis, California | |
| Community Medical Center Toms River, New Jersey | |
| Cooper Hospital University Medical Center Camden, New Jersey | |
| Corewell Health Beaumont Troy Hospital Troy, Michigan | |
| Corewell Health Grand Rapids Hospitals - Butterworth Hospital Grand Rapids, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
| Corewell Health William Beaumont University Hospital Royal Oak, Michigan | |
| CoxHealth South Hospital Springfield, Missouri | |
| Crossroads Cancer Center Effingham, Illinois | Site Public Contact - (morganthaler.jodi@mhsil.com) |
| Dana-Farber Cancer Institute Boston, Massachusetts | |
| Danbury Hospital Danbury, Connecticut | |
| Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center Lebanon, New Hampshire | Site Public Contact - (cancer.research.nurse@dartmouth.edu) |
| Decatur Memorial Hospital Decatur, Illinois | Site Public Contact - (morganthaler.jodi@mhsil.com) |
| Dickstein Cancer Treatment Center White Plains, New York | |
| Doctors Hospital Columbus, Ohio | |
| Dublin Methodist Hospital Dublin, Ohio | |
| Duke Cancer Center Raleigh Raleigh, North Carolina | |
| Duke University Medical Center Durham, North Carolina | |
| Duke Women's Cancer Care Raleigh Raleigh, North Carolina | |
| ECU Health Oncology Kinston Kinston, North Carolina | |
| East Carolina University Greenville, North Carolina | Site Public Contact - (eubankss@ecu.edu) |
| Edwards Comprehensive Cancer Center Huntington, West Virginia | Site Public Contact - (Christina.Cole@chhi.org) |
| Englewood Hospital and Medical Center Englewood, New Jersey | |
| Ephrata Cancer Center Ephrata, Pennsylvania | |
| Forbes Hospital Monroeville, Pennsylvania | |
| Fred Hutchinson Cancer Center Seattle, Washington | |
| Genesis Healthcare System Cancer Care Center Zanesville, Ohio | |
| Good Samaritan Hospital - Cincinnati Cincinnati, Ohio | |
| Grant Medical Center Columbus, Ohio | |
| Great Falls Clinic Great Falls, Montana | |
| Greater Baltimore Medical Center Baltimore, Maryland | |
| Gundersen Lutheran Medical Center La Crosse, Wisconsin | Site Public Contact - (cancerctr@gundersenhealth.org) |
| Guthrie Medical Group PC-Robert Packer Hospital Sayre, Pennsylvania | |
| Hartford Hospital Hartford, Connecticut | |
| Heartland Regional Medical Center Saint Joseph, Missouri | Site Public Contact - (Trisha.England2@mymlc.com) |
| Hematology Oncology Associates of Central New York-East Syracuse East Syracuse, New York | |
| Henry Ford Health Providence Novi Hospital Novi, Michigan | Site Public Contact - (kfife3@hfhs.org) |
| Henry Ford Health Providence Southfield Hospital Southfield, Michigan | Site Public Contact - (kfife3@hfhs.org) |
| Henry Ford Health Saint John Hospital Detroit, Michigan | Site Public Contact - (Kkeenan1@hfhs.org) |
| Henry Ford Health Warren Hospital Warren, Michigan | Site Public Contact - (kforman1@hfhs.org) |
| Henry Ford Hospital Detroit, Michigan | Site Public Contact - (CTOResearch@hfhs.org) |
| Hickman Cancer Center Adrian, Michigan | |
| Hillcrest Hospital Cancer Center Mayfield Heights, Ohio | |
| Holy Name Hospital Teaneck, New Jersey | |
| Idaho Urologic Institute-Meridian Meridian, Idaho | |
| Illinois CancerCare-Bloomington Bloomington, Illinois | |
| Illinois CancerCare-Canton Canton, Illinois | |
| Illinois CancerCare-Carthage Carthage, Illinois | |
| Illinois CancerCare-Eureka Eureka, Illinois | |
| Illinois CancerCare-Galesburg Galesburg, Illinois | |
| Illinois CancerCare-Kewanee Clinic Kewanee, Illinois | |
| Illinois CancerCare-Macomb Macomb, Illinois | |
| Illinois CancerCare-Ottawa Clinic Ottawa, Illinois | |
| Illinois CancerCare-Pekin Pekin, Illinois | |
| Illinois CancerCare-Peoria Peoria, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Peru Peru, Illinois | |
| Illinois CancerCare-Princeton Princeton, Illinois | |
| Inova Fair Oaks Hospital Fairfax, Virginia | Site Public Contact - (Stephanie.VanBebber@inova.org) |
| Inova Fairfax Hospital Falls Church, Virginia | Site Public Contact - (Stephanie.VanBebber@inova.org) |
| Inova Loudoun Hospital Leesburg, Virginia | Site Public Contact - (Keary.janet@inova.org) |
| Inova Schar Cancer Institute Fairfax, Virginia | Site Public Contact - (Stephanie.VanBebber@inova.org) |
| Iowa Lutheran Hospital Des Moines, Iowa | |
| Iowa Methodist Medical Center Des Moines, Iowa | |
| Jefferson Abington Hospital Abington, Pennsylvania | Steven J. Cohen - (steven.cohen@jefferson.edu) |
| Jefferson Hospital Jefferson Hills, Pennsylvania | |
| Jersey City Medical Center Jersey City, New Jersey | Site Public Contact - (ctsucontact@westat.com) |
| Jersey Shore Medical Center Neptune City, New Jersey | |
| John H Stroger Jr Hospital of Cook County Chicago, Illinois | |
| Jupiter Medical Center Jupiter, Florida | Site Public Contact - (clinicaltrials@jupitermed.com) |
| Juravinski Cancer Centre at Hamilton Health Sciences Hamilton, Ontario | |
| Kaiser Permanente Downtown Commons Sacramento, California | Site Public Contact - (kpoct@kp.org) |
| Kaiser Permanente Dublin Dublin, California | |
| Kaiser Permanente Fresno Orchard Plaza Fresno, California | |
| Kaiser Permanente Los Angeles Medical Center Los Angeles, California | Site Public Contact - (clinical.trials@kp.org) |
| Kaiser Permanente Medical Center - Santa Clara Santa Clara, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente Medical Center-Vacaville Vacaville, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente Moanalua Medical Center Honolulu, Hawaii | Site Public Contact - (shelley.a.clark@kp.org) |
| Kaiser Permanente Northwest Portland, Oregon | |
| Kaiser Permanente San Leandro San Leandro, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente West Los Angeles Los Angeles, California | Site Public Contact - (clinical.trials@kp.org) |
| Kaiser Permanente-Anaheim Anaheim, California | Site Public Contact - (clinical.trials@kp.org) |
| Kaiser Permanente-Bellflower Bellflower, California | Site Public Contact - (clinical.trials@kp.org) |
| Kaiser Permanente-Deer Valley Medical Center Antioch, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-Fremont Fremont, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-Fresno Fresno, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-Irvine Irvine, California | Site Public Contact - (clinical.trials@kp.org) |
| Kaiser Permanente-Modesto Modesto, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-Oakland Oakland, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-Redwood City Redwood City, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-Richmond Richmond, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-Riverside Riverside, California | Site Public Contact - (clinical.trials@kp.org) |
| Kaiser Permanente-Roseville Roseville, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-San Diego Zion San Diego, California | Site Public Contact - (clinical.trials@kp.org) |
| Kaiser Permanente-San Francisco San Francisco, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-Santa Rosa Santa Rosa, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-Santa Teresa-San Jose San Jose, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-South Sacramento Sacramento, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-South San Francisco South San Francisco, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-Stockton Stockton, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-Vallejo Vallejo, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-Walnut Creek Walnut Creek, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser San Rafael-Gallinas San Rafael, California | Site Public Contact - (Kpoct@kp.org) |
| Katmai Oncology Group Anchorage, Alaska | |
| Kingston Health Sciences Centre Kingston, Ontario | Site Public Contact - (cc-clinicaltrials@kgh.kari.net) |
| Kootenai Clinic Cancer Services - Post Falls Post Falls, Idaho | |
| Kootenai Health - Coeur d'Alene Coeur d'Alene, Idaho | |
| LSU Health Baton Rouge-North Clinic Baton Rouge, Louisiana | Site Public Contact - (research@ololrmc.com) |
| Lahey Hospital and Medical Center Burlington, Massachusetts | |
| Lahey Medical Center-Peabody Peabody, Massachusetts | |
| Lakeland Regional Health Hollis Cancer Center Lakeland, Florida | |
| Langlade Hospital and Cancer Center Antigo, Wisconsin | |
| Lehigh Valley Hospital-Cedar Crest Allentown, Pennsylvania | Site Public Contact - (Morgan_M.Horton@lvhn.org) |
| Lenox Hill Hospital New York, New York | |
| Licking Memorial Hospital Newark, Ohio | |
| Logan Health Medical Center Kalispell, Montana | |
| Long Island Jewish Medical Center New Hyde Park, New York | |
| Los Angeles General Medical Center Los Angeles, California | Site Public Contact - (uscnorrisinfo@med.usc.edu) |
| Louisiana Hematology Oncology Associates LLC Baton Rouge, Louisiana | Site Public Contact - (clinicalresearch@marybird.com) |
| Loyola University Medical Center Maywood, Illinois | |
| MU Health - University Hospital/Ellis Fischel Cancer Center Columbia, Missouri | |
| MU Health Care Goldschmidt Cancer Center Jefferson City, Missouri | |
| Manhattan Eye Ear and Throat Hospital New York, New York | |
| Marietta Memorial Hospital Marietta, Ohio | |
| Marshfield Medical Center - Minocqua Minocqua, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center - Weston Weston, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center-EC Cancer Center Eau Claire, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center-Marshfield Marshfield, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center-Rice Lake Rice Lake, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center-River Region at Stevens Point Stevens Point, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Mary Bird Perkins Cancer Center Baton Rouge, Louisiana | Site Public Contact - (clinicalresearch@marybird.com) |
| Mary Greeley Medical Center Ames, Iowa | |
| Massachusetts General Hospital Cancer Center Boston, Massachusetts | |
| McFarland Clinic - Ames Ames, Iowa | |
| MedStar Georgetown University Hospital Washington D.C., District of Columbia | |
| Medical Center of Baton Rouge Baton Rouge, Louisiana | Site Public Contact - (Camille.Beck@Ochsner.org) |
| Medical University of South Carolina Charleston, South Carolina | Site Public Contact - (hcc-clinical-trials@musc.edu) |
| Medstar Washington Hospital Center Washington D.C., District of Columbia | |
| Memorial Hospital of Carbondale Carbondale, Illinois | |
| Memorial Hospital of South Bend South Bend, Indiana | |
| Memorial Medical Center Modesto, California | |
| Memorial Sloan Kettering Basking Ridge Basking Ridge, New Jersey | |
| Memorial Sloan Kettering Bergen Montvale, New Jersey | |
| Memorial Sloan Kettering Cancer Center New York, New York | |
| Memorial Sloan Kettering Commack Commack, New York | |
| Memorial Sloan Kettering Monmouth Middletown, New Jersey | |
| Memorial Sloan Kettering Nassau Uniondale, New York | |
| Memorial Sloan Kettering Westchester Harrison, New York | |
| Mercy Cancer Center - Cape Girardeau Cape Girardeau, Missouri | |
| Mercy Clinic-Rolla-Cancer and Hematology Rolla, Missouri | |
| Mercy Hospital Fort Smith Fort Smith, Arkansas | |
| Mercy Hospital Joplin Joplin, Missouri | |
| Mercy Hospital Oklahoma City Oklahoma City, Oklahoma | |
| Mercy Hospital Saint Louis St Louis, Missouri | |
| Mercy Hospital South St Louis, Missouri | |
| Mercy Hospital Springfield Springfield, Missouri | |
| Mercy Medical Center - Des Moines Des Moines, Iowa | Site Public Contact - (cancerresearch@mercydesmoines.org) |
| Mercy Oncology and Hematology - Clayton-Clarkson Ballwin, Missouri | |
| Methodist Medical Center of Illinois Peoria, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Methodist West Hospital West Des Moines, Iowa | |
| MetroHealth Medical Center Cleveland, Ohio | Site Public Contact - (ababal@metrohealth.org) |
| Miami Valley Cancer Care and Infusion Greenville, Ohio | |
| Miami Valley Hospital Dayton, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Miami Valley Hospital North Dayton, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Miami Valley Hospital South Centerville, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Midstate Medical Center Meriden, Connecticut | |
| Mills Health Center San Mateo, California | |
| Mills-Peninsula Medical Center Burlingame, California | |
| Missouri Baptist Medical Center St Louis, Missouri | |
| Missouri Baptist Sullivan Hospital Sullivan, Missouri | |
| Mobile Infirmary Medical Center Mobile, Alabama | |
| Monmouth Medical Center Long Branch, New Jersey | Site Public Contact - (mary.danish@rwjbh.org) |
| Monmouth Medical Center Southern Campus Lakewood, New Jersey | Site Public Contact - (mary.danish@rwjbh.org) |
| Montefiore Medical Center - Moses Campus The Bronx, New York | |
| Montefiore Medical Center-Einstein Campus The Bronx, New York | |
| Montefiore Medical Center-Weiler Hospital The Bronx, New York | |
| Mount Carmel East Hospital Columbus, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Mount Carmel Grove City Hospital Grove City, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Mount Carmel Health Center West Columbus, Ohio | |
| Mount Sinai Comprehensive Cancer Center at Aventura Aventura, Florida | |
| Mount Sinai Hospital New York, New York | |
| Mount Sinai Medical Center Miami Beach, Florida | |
| Mount Sinai West New York, New York | |
| MyMichigan Medical Center Saginaw Saginaw, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro Jonesboro, Arkansas | Site Public Contact - (Emily.Carvell@bmhcc.org) |
| Nebraska Methodist Hospital Omaha, Nebraska | |
| Newark Radiation Oncology Newark, Ohio | |
| North Coast Cancer Care Sandusky, Ohio | |
| North Shore University Hospital Manhasset, New York | |
| Northeast Georgia Medical Center-Gainesville Gainesville, Georgia | Site Public Contact - (cancerpatient.navigator@nghs.com) |
| Northshore Oncology Associates-Covington Covington, Louisiana | Site Public Contact - (clinicalresearch@marybird.com) |
| Northwell Health Cancer Institute at Huntington Greenlawn, New York | |
| Northwell Health Imbert Cancer Center Bay Shore, New York | |
| Northwell Health/Center for Advanced Medicine Lake Success, New York | |
| Northwestern Medicine Cancer Center Delnor Geneva, Illinois | Site Public Contact - (Donald.Smith3@nm.org) |
| Northwestern Medicine Cancer Center Kishwaukee DeKalb, Illinois | Site Public Contact - (Donald.Smith3@nm.org) |
| Northwestern Medicine Cancer Center Warrenville Warrenville, Illinois | Site Public Contact - (Donald.Smith3@nm.org) |
| Northwestern Medicine Oak Brook Oak Brook, Illinois | Site Public Contact - (nctnprogram_rhlccc@northwestern.edu) |
| Northwestern Medicine Orland Park Orland Park, Illinois | Site Public Contact - (nctnprogram_rhlccc@northwestern.edu) |
| Northwestern University Chicago, Illinois | Site Public Contact - (cancer@northwestern.edu) |
| Norwalk Hospital Norwalk, Connecticut | Site Public Contact - (jennifer.long@norwalkhealth.org) |
| Ochsner Hematology Oncology North Shore - Covington (West Region) Covington, Louisiana | Site Public Contact - (Cheryl.kesler@ochsner.org) |
| Ochsner High Grove Baton Rouge, Louisiana | Site Public Contact - (Camielle.beck@ochsner.org) |
| Ochsner Medical Center Jefferson New Orleans, Louisiana | Site Public Contact - (Elisemarie.curry@ochsner.org) |
| Ochsner Medical Center Kenner Kenner, Louisiana | Site Public Contact - (awendt@ochsner.org) |
| Odette Cancer Centre- Sunnybrook Health Sciences Centre Toronto, Ontario | |
| Ohio State University Comprehensive Cancer Center Columbus, Ohio | |
| OhioHealth Mansfield Hospital Mansfield, Ohio | |
| OptumCare Cancer Care at Charleston Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Oregon Health and Science University Portland, Oregon | |
| Ottawa Hospital and Cancer Center-General Campus Ottawa, Ontario | |
| Our Lady of the Lake Physician Group Baton Rouge, Louisiana | Site Public Contact - (research@ololrmc.com) |
| Overlake Medical Center Bellevue, Washington | |
| Palo Alto Medical Foundation Health Care Palo Alto, California | |
| Palo Alto Medical Foundation-Camino Division Mountain View, California | |
| Palo Alto Medical Foundation-Sunnyvale Sunnyvale, California | |
| PeaceHealth Saint John Medical Center Longview, Washington | |
| PeaceHealth Saint Joseph Medical Center Bellingham, Washington | |
| PeaceHealth Southwest Medical Center Vancouver, Washington | |
| PeaceHealth United General Medical Center Sedro-Woolley, Washington | |
| Penn State Milton S Hershey Medical Center Hershey, Pennsylvania | Site Public Contact - (CTO@hmc.psu.edu) |
| Phelps Health Delbert Day Cancer Institute Rolla, Missouri | |
| Phoebe Putney Memorial Hospital Albany, Georgia | Site Public Contact - (ga_cares@augusta.edu) |
| Prisma Health Cancer Institute - Eastside Greenville, South Carolina | Site Public Contact - (Kim.Williams3@prismahealth.org) |
| Prisma Health Cancer Institute - Faris Greenville, South Carolina | Site Public Contact - (Kim.Williams3@prismahealth.org) |
| Prisma Health Cancer Institute - Greer Greer, South Carolina | Site Public Contact - (Kim.Williams3@prismahealth.org) |
| Prisma Health Cancer Institute - Seneca Seneca, South Carolina | Site Public Contact - (Kim.Williams3@prismahealth.org) |
| Providence Alaska Medical Center Anchorage, Alaska | |
| Providence Cancer Institute Clackamas Clinic Clackamas, Oregon | |
| Providence Newberg Medical Center Newberg, Oregon | Site Public Contact - (CanRsrchStudies@providence.org) |
| Providence Portland Medical Center Portland, Oregon | Site Public Contact - (CanRsrchStudies@providence.org) |
| Providence Regional Cancer Partnership Everett, Washington | Site Public Contact - (marilyn.birchman@providence.org) |
| Providence Regional Cancer System-Aberdeen Aberdeen, Washington | |
| Providence Regional Cancer System-Centralia Centralia, Washington | |
| Providence Regional Cancer System-Lacey Lacey, Washington | |
| Providence Saint Joseph Medical Center/Disney Family Cancer Center Burbank, California | |
| Providence Saint Mary Regional Cancer Center Walla Walla, Washington | |
| Providence Saint Vincent Medical Center Portland, Oregon | Site Public Contact - (CanRsrchStudies@providence.org) |
| Providence Willamette Falls Medical Center Oregon City, Oregon | Site Public Contact - (CanRsrchStudies@providence.org) |
| QEII Health Sciences Centre/Nova Scotia Health Authority Halifax, Nova Scotia | |
| Queen's Medical Center Honolulu, Hawaii | |
| Queens Cancer Center Rego Park, New York | |
| Ralph H Johnson VA Medical Center Charleston, South Carolina | Site Public Contact - (ashley.salvo@va.gov) |
| Reading Hospital West Reading, Pennsylvania | |
| Regional Cancer Center-Lee Memorial Health System Fort Myers, Florida | Site Public Contact - (protocols@AllianceNCTN.org) |
| Renown Regional Medical Center Reno, Nevada | Site Public Contact - (research@sncrf.org) |
| Riverside Methodist Hospital Columbus, Ohio | |
| Rush-Copley Medical Center Aurora, Illinois | |
| Rutgers Cancer Institute of New Jersey New Brunswick, New Jersey | |
| SIH Cancer Institute Carterville, Illinois | Site Public Contact - (clinical.research@sih.net) |
| SSM Health Good Samaritan Mount Vernon, Illinois | |
| SUNY Upstate Medical Center-Community Campus Syracuse, New York | |
| Saint Alphonsus Cancer Care Center-Boise Boise, Idaho | Site Public Contact - (stephanie.couch@stjoeshealth.org) |
| Saint Alphonsus Cancer Care Center-Caldwell Caldwell, Idaho | Site Public Contact - (stephanie.couch@stjoeshealth.org) |
| Saint Alphonsus Cancer Care Center-Nampa Nampa, Idaho | Site Public Contact - (mccinfo@mtcancer.org) |
| Saint Ann's Hospital Westerville, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Saint Barnabas Medical Center Livingston, New Jersey | Site Public Contact - (joanne.loeb@rwjbh.org) |
| Saint Charles Health System Bend, Oregon | |
| Saint Francis Medical Center Cape Girardeau, Missouri | |
| Saint Joseph Hospital - Orange Orange, California | |
| Saint Luke's Cancer Institute - Boise Boise, Idaho | Site Public Contact - (eslinget@slhs.org) |
| Saint Luke's Cancer Institute - Fruitland Fruitland, Idaho | Site Public Contact - (eslinget@slhs.org) |
| Saint Luke's Cancer Institute - Meridian Meridian, Idaho | Site Public Contact - (eslinget@slhs.org) |
| Saint Luke's Cancer Institute - Nampa Nampa, Idaho | Site Public Contact - (eslinget@slhs.org) |
| Saint Luke's Cancer Institute - Twin Falls Twin Falls, Idaho | Site Public Contact - (eslinget@slhs.org) |
| Saint Luke's Hospital of Kansas City Kansas City, Missouri | |
| Saint Vincent Hospital Erie, Pennsylvania | |
| Sainte Genevieve County Memorial Hospital Sainte Genevieve, Missouri | |
| Sanford Broadway Medical Center Fargo, North Dakota | Site Public Contact - (OncologyClinicalTrialsFargo@sanfordhealth.org) |
| Sanford Cancer Center Oncology Clinic Sioux Falls, South Dakota | Site Public Contact - (OncologyClinicTrialsSF@sanfordhealth.org) |
| Sanford Roger Maris Cancer Center Fargo, North Dakota | Site Public Contact - (OncologyClinicalTrialsFargo@sanfordhealth.org) |
| Sanford USD Medical Center - Sioux Falls Sioux Falls, South Dakota | Site Public Contact - (OncologyClinicalTrialsSF@SanfordHealth.org) |
| Schulze Family Foundation Cancer Clinic - Bonita Health Center Bonita Springs, Florida | Site Public Contact - (RCCR@leehealth.org) |
| Sechler Family Cancer Center Lebanon, Pennsylvania | |
| Sentara Leigh Hospital Norfolk, Virginia | |
| Sentara Norfolk General Hospital Norfolk, Virginia | |
| Sibley Memorial Hospital Washington D.C., District of Columbia | Site Public Contact - (jquiver1@jhmi.edu) |
| Smilow Cancer Hospital Care Center - Guilford Guilford, Connecticut | |
| Smilow Cancer Hospital Care Center - Waterford Waterford, Connecticut | |
| Smilow Cancer Hospital Care Center - Westerly Westerly, Rhode Island | |
| Smilow Cancer Hospital Care Center at Glastonbury Glastonbury, Connecticut | |
| Smilow Cancer Hospital Care Center at Greenwich Greenwich, Connecticut | |
| Smilow Cancer Hospital Care Center at Saint Francis Hartford, Connecticut | |
| Smilow Cancer Hospital Care Center-Fairfield Fairfield, Connecticut | |
| Smilow Cancer Hospital Care Center-Trumbull Trumbull, Connecticut | |
| Smilow Cancer Hospital-Derby Care Center Derby, Connecticut | |
| Smilow Cancer Hospital-Orange Care Center Orange, Connecticut | |
| Smilow Cancer Hospital-Torrington Care Center Torrington, Connecticut | |
| Smilow Cancer Hospital-Waterbury Care Center Waterbury, Connecticut | |
| South Shore University Hospital Bay Shore, New York | |
| Southern Illinois University School of Medicine Springfield, Illinois | |
| Southern Ohio Medical Center Portsmouth, Ohio | |
| Springfield Clinic Springfield, Illinois | |
| Springfield Memorial Hospital Springfield, Illinois | Site Public Contact - (pallante.beth@mhsil.com) |
| Stanford Cancer Institute Palo Alto Palo Alto, California | Site Public Contact - (ccto-office@stanford.edu) |
| State University of New York Upstate Medical University Syracuse, New York | |
| Staten Island University Hospital Staten Island, New York | |
| Stony Brook University Medical Center Stony Brook, New York | |
| Sutter Cancer Centers Radiation Oncology Services-Auburn Auburn, California | |
| Sutter Cancer Centers Radiation Oncology Services-Cameron Park Cameron Park, California | |
| Sutter Cancer Centers Radiation Oncology Services-Roseville Roseville, California | |
| Sutter Medical Center Sacramento Sacramento, California | |
| Sutter Roseville Medical Center Roseville, California | |
| Sutter Solano Medical Center/Cancer Center Vallejo, California | |
| Swedish Cancer Institute-Edmonds Edmonds, Washington | |
| Swedish Cancer Institute-Issaquah Issaquah, Washington | |
| Swedish Medical Center-Ballard Campus Seattle, Washington | |
| Swedish Medical Center-First Hill Seattle, Washington | |
| Tampa General Hospital Tampa, Florida | Site Public Contact - (syapchanyk@tgh.org) |
| Terrebonne General Medical Center Houma, Louisiana | Site Public Contact - (ann.hooks@tgmc.com) |
| The Cancer Institute at Saint Francis Hospital East Hills, New York | |
| The Carle Foundation Hospital Urbana, Illinois | |
| The Don and Sybil Harrington Cancer Center Amarillo, Texas | Site Public Contact - (Gina.Cravey@bsahs.org) |
| The Hospital of Central Connecticut New Britain, Connecticut | |
| The James Graham Brown Cancer Center at University of Louisville Louisville, Kentucky | |
| The Mark H Zangmeister Center Columbus, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| The Research Institute of the McGill University Health Centre (MUHC) Montreal, Quebec | Site Public Contact - (evelyn.ortega@muhc.mcgill.ca) |
| The Valley Hospital - Luckow Pavilion Paramus, New Jersey | Site Public Contact - (clinicaltrialsresearch@valleyhealth.com) |
| Thomas Hospital Fairhope, Alabama | |
| Thomas Jefferson University Hospital Philadelphia, Pennsylvania | |
| Toledo Clinic Cancer Centers-Toledo Toledo, Ohio | |
| Trinity Health Medical Center - Brighton Brighton, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Trinity Health Medical Center - Canton Canton, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Trinity Health Saint Joseph Mercy Hospital Ann Arbor Ann Arbor, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Tufts Medical Center Boston, Massachusetts | Site Public Contact - (ContactUsCancerCenter@TuftsMedicalCenter.org) |
| UC Irvine Health Cancer Center-Newport Costa Mesa, California | |
| UC Irvine Health/Chao Family Comprehensive Cancer Center Orange, California | |
| UC San Diego Medical Center - Hillcrest San Diego, California | Site Public Contact - (rhabbaba@health.ucsd.edu) |
| UC San Diego Moores Cancer Center La Jolla, California | Site Public Contact - (cancercto@ucsd.edu) |
| UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care Irvine, California | Site Public Contact - (ucstudy@uci.edu) |
| UCSF Medical Center-Mission Bay San Francisco, California | Site Public Contact - (cancertrials@ucsf.edu) |
| UF Health Cancer Institute - Gainesville Gainesville, Florida | Site Public Contact - (cancer-center@ufl.edu) |
| UI Health Care Mission Cancer and Blood - Ankeny Clinic Ankeny, Iowa | |
| UI Health Care Mission Cancer and Blood - Des Moines Clinic Des Moines, Iowa | |
| UM Saint Joseph Medical Center Towson, Maryland | |
| UM Sylvester Comprehensive Cancer Center at Coral Gables Coral Gables, Florida | |
| UM Sylvester Comprehensive Cancer Center at Deerfield Beach Deerfield Beach, Florida | |
| UM Sylvester Comprehensive Cancer Center at Kendall Miami, Florida | |
| UM Sylvester Comprehensive Cancer Center at Plantation Plantation, Florida | |
| USC / Norris Comprehensive Cancer Center Los Angeles, California | |
| UT Southwestern Clinical Center at Richardson/Plano Richardson, Texas | Site Public Contact - (Suzanne.cole@utsouthwestern.edu) |
| UT Southwestern Simmons Cancer Center - RedBird Dallas, Texas | Site Public Contact - (canceranswerline@utsouthwestern.edu) |
| UT Southwestern/Simmons Cancer Center-Dallas Dallas, Texas | Site Public Contact - (canceranswerline@UTSouthwestern.edu) |
| UT Southwestern/Simmons Cancer Center-Fort Worth Fort Worth, Texas | Site Public Contact - (canceranswerline@UTSouthwestern.edu) |
| University Medical Center New Orleans New Orleans, Louisiana | Site Public Contact - (emede1@lsuhsc.edu) |
| University of Alabama at Birmingham Cancer Center Birmingham, Alabama | |
| University of Arizona Cancer Center-North Campus Tucson, Arizona | |
| University of Arkansas for Medical Sciences Little Rock, Arkansas | |
| University of California Davis Comprehensive Cancer Center Sacramento, California | |
| University of Chicago Comprehensive Cancer Center Chicago, Illinois | |
| University of Chicago Medicine-Orland Park Orland Park, Illinois | |
| University of Illinois Chicago, Illinois | |
| University of Iowa/Holden Comprehensive Cancer Center Iowa City, Iowa | |
| University of Kentucky/Markey Cancer Center Lexington, Kentucky | |
| University of Miami Miller School of Medicine-Sylvester Cancer Center Miami, Florida | |
| University of Michigan Rogel Cancer Center Ann Arbor, Michigan | Site Public Contact - (CancerAnswerLine@med.umich.edu) |
| University of New Mexico Cancer Center Albuquerque, New Mexico | Site Public Contact - (HSC-ClinicalTrialInfo@salud.unm.edu) |
| University of Oklahoma Health Sciences Center Oklahoma City, Oklahoma | Site Public Contact - (ou-clinical-trials@ouhsc.edu) |
| University of Rochester Rochester, New York | |
| University of South Alabama Mitchell Cancer Institute Mobile, Alabama | Site Public Contact - (pfrancisco@usouthal.edu) |
| University of Tennessee - Knoxville Knoxville, Tennessee | |
| University of Texas Health Science Center at San Antonio San Antonio, Texas | |
| University of Toledo Toledo, Ohio | |
| University of Vermont Medical Center Burlington, Vermont | |
| University of Washington Medical Center - Montlake Seattle, Washington | |
| Upper Valley Medical Center Troy, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Upstate Cancer Center at Oswego Oswego, New York | |
| Upstate Cancer Center at Verona Verona, New York | |
| VCU Community Memorial Health Center South Hill, Virginia | Site Public Contact - (nemer.elmouallem@vcuhealth.org) |
| VCU Massey Comprehensive Cancer Center Richmond, Virginia | Site Public Contact - (CTOclinops@vcu.edu) |
| Valley Health System Ridgewood Campus Ridgewood, New Jersey | Site Public Contact - (clinicaltrialsresearch@valleyhealth.com) |
| Valley Radiation Oncology Peru, Illinois | |
| Wake Forest University Health Sciences Winston-Salem, North Carolina | |
| Washington University School of Medicine St Louis, Missouri | |
| Wayne State University/Karmanos Cancer Institute Detroit, Michigan | Site Public Contact - (ctoadmin@karmanos.org) |
| Weisberg Cancer Treatment Center Farmington Hills, Michigan | Site Public Contact - (ctoadmin@karmanos.org) |
| Welch Cancer Center Sheridan, Wyoming | |
| WellSpan Health-York Cancer Center York, Pennsylvania | |
| WellSpan Health-York Hospital York, Pennsylvania | |
| West Michigan Cancer Center Kalamazoo, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
| West Penn Hospital Pittsburgh, Pennsylvania | |
| West Virginia University Charleston Division Charleston, West Virginia | |
| Western Illinois Cancer Treatment Center Galesburg, Illinois | |
| Wexford Health and Wellness Pavilion Wexford, Pennsylvania | |
| Wilmot Cancer Institute at Webster Webster, New York | Site Public Contact - (WCICTOresearch@urmc.rochester.edu) |
| Yale University New Haven, Connecticut | |
| Yale-New Haven Hospital North Haven Medical Center North Haven, Connecticut |
Treatment of GVHD in HSCT)Recipients Using AAT + Corticosteroids Compared With Corticosteroids Alone
Candler, Kathryn, S. - kcandler@vcu.edu
Clark, William, B
NCT04167514
HM20020328
drug: Alpha-1 anti-tripsin (aat)
Other Hematopoietic
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Study Locations
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Candler, Kathryn, S. - (kcandler@vcu.edu) |