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478 Study Matches
Impacts of COVID-19 on Cigarette Smoking Behaviors
ctrrecruit@vcu.edu
Breland, Alison
19171
HM20019258
Any Site
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia |
Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT 2 (SEXTANT 2)
Suna Chung, MPH - schung60@jhu.edu
Kates, Stephen, L
NCT04678154
HM20022236
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Inclusion Criteria:
• Injury meeting at least one of the following criteria: a. Gustilo type III fractures of the tibia (OTA 41 plateau, OTA 42 shaft and OTA 43 pilon); ankle (OTA 44); calcaneus (OTA 82) and/or talus (OTA 81) with injury characteristics meeting at least one of the following criteria: i. All IIIB fractures ii. IIIA fractures that require a planned second debridement prior to definitive closure / coverage iii. IIIA fractures with extensive contamination or muscle damage precluding definitive internal fixation at the time of initial surgery iv. IIIA fractures with extensive degloving or wound greater than 10 cm after debridement (if indicated, primary wound closure is allowed. Primary wound closure refers to the definitive closure of the wound at the initial surgical event, without plans for re-entry for additional debridement and/or fracture fixation) v. IIIA fractures severe fracture comminution resulting from high energy trauma (if indicated, primary wound closure/coverage is allowed) vi. IIIA fractures with AO/OTA OFC contamination level of severe with material imbedded into bone or soft tissue or with a severe high risk environmental contamination from farm, fecal, dirty water inoculation or other equivalent (if indicated, primary wound closure/coverage is allowed) vii. IIIA Fractures where the skin could be closed after extensive muscle or bone removal (if indicated, primary wound closure/coverage is allowed) viii. IIIA fractures with bone loss resulting in a circumferential gap of 1 cm after debridement (if indicated, primary wound closure/coverage is allowed) ix. Fractures where fasciotomies were performed for impending or diagnosed compartment syndromes (regardless of the initial open or closed classification of the fracture x. Traumatic "zone-of-injury" trans-tibial amputations requiring DPC, and/or flap coverage
• Ages 18 - 64 years inclusive
• Patients may have risk factors for infection including diabetes, immunosuppression from steroids or other medications, HIV, or other infections.
• Patients may have a traumatic brain injury.
• Patients may have other fractures including spine, upper extremity fractures, contralateral lower extremity injuries, ipsilateral pelvis, hip, femur, or foot injuries.
• Patients may be treated initially at an outside institution prior to transferring to the study institution, as long as the definitive wound closure/coverage was not performed prior to entrance into the study.
• Patients with bilateral injuries that meet inclusion criteria may be included, but only the limb rated as "more severe" by the treating surgeon will be enrolled in the study.
• Patients may have co-existing non-tibial or hindfoot infections, with or without antibiotic treatment.
• Patients may be definitively stabilized using any method (nail, plate, ex fix, or cast).
• Patients may have fasciotomy.
Exclusion Criteria:
• Patient speaks neither English or Spanish
• Patient in current therapy for a wound, implant or fracture site infection related to the study site.
• Patient is pregnant, potentially pregnant, or lactating.
• Patient likely to have difficulty maintaining follow-up, including:
• Diagnosis of a severe psychiatric condition
• Intellectually challenged without adequate family support
• Resides outside of the hospital's catchment area, unless willing to follow-up by phone or telemedicine
• Planning to follow-up at another medical center, unless willing to follow-up by phone or telemedicine
• Being a prisoner
• Not having a means of contact (address, cell phone, home phone, e-mail)
DRUG: Standard of care, DRUG: Vancomycin and Tobramycin
Post Operative Surgical Site Infection
Surgical site infection risk prevention, Bacterial species type and antibacterial sensitivities
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Study Locations
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| Location | Contacts |
|---|---|
| Atrium Health Carolinas Medical Center Charlotte, North Carolina | |
| Atrium Health Wake Forest Baptist Winston-Salem, North Carolina | Martha Holden - (mholden@wakehealth.edu) |
| Brown University/Rhode Island Hospital Providence, Rhode Island | |
| Dartmouth Hitchcock Lebanon, New Hampshire | Devin Mullin - (devin.s.mullin@hitchcock.org) |
| Emory University School Of Medicine Atlanta, Georgia | |
| Harvard/Mass General/Brigham Hospitals Boston, Massachusetts | Thiru Wignakumar - (twignakumar@bwh.harvard.edu) |
| Hennepin County Medical Center / Minneapolis Minneapolis, Minnesota | |
| Indiana University School of Medicine - Methodist Hospital Indianapolis, Indiana | Maricella Diaz - (diaz4@iu.edu) |
| Indiana University/Eskenazi Health Indianapolis, Indiana | Molly Moore - (momfreed@iupui.edu) |
| Inova Fairfax Medical Campus Falls Church, Virginia | Senay Ghidei - (Senay.Ghidei@Inova.org) |
| Jamaica Hospital Medical Center Richmond Hill, New York | |
| LSU Health Sciences New Orleans, Louisiana | Jessica Rivera - (jrive5@lsuhsc.edu) |
| MetroHealth Cleveland, Ohio | Anna Vergon - (avergon@metrohealth.org) |
| Ohio State University Wexner Medical Center Columbus, Ohio | Jessica Wiseman - (jessica.wiseman@osumc.edu) |
| Rhode Island Hospital/Brown University Providence, Rhode Island | MJ Crisco - (mjcrisco@uoi.com) |
| St Mary's University/Tenent Health West Palm Beach, Florida | Tracy Rodriguez - (tracy.rodriguez@tenethealth.com) |
| Stanford University Stanford, California | Carina Tedesco - (ctedesco@stanford.edu) |
| Temple University Philadelphia, Pennsylvania | Adam Lloyd-Jones - (adam.lloyd-jones@temple.edu) |
| University of California at San Francisco San Francisco, California | Eleni Berhaneselase - (Eleni.Berhaneselase@ucsf.edu) |
| University of Colorado Anschutz Medical Campus Aurora, Colorado | Fahim Choudhury - (fahim.choudhury@cuanschutz.edu) |
| University of Kentucky Lexington, Kentucky | Matthew Eubank - (mseuba01@uky.edu) |
| University of Maryland , MD Department of Orthopaedics Baltimore, Maryland | Yasmin Degani, MPH - (ydegani@som.umaryland.edu) |
| University of Mississippi Medical Center Jackson, Mississippi | Sandra Powe - (spowe@umc.edu) |
| University of North Carolina at Chapel Hill Chapel Hill, North Carolina | Nevaeh Nez - (nevaeh_nez@med.unc.edu) |
| University of Oklahoma College of Medicine Oklahoma City, Oklahoma | Lyndee Nguyen - (lyndee-nguyen@ouhsc.edu) |
| University of Texas Health Science Center - Houston Houston, Texas | Sterling Boutte - (Sterling.Boutte@uth.tmc.edu) |
| University of Virginia Charlottesville, Virginia | Eric McVey - (EDM9U@hscmail.mcc.virginia.edu) |
| Vanderbilt University Medical Center Nashville, Tennessee | Karen Trochez - (karen.m.trochez@Vanderbilt.Edu) |
| Virginia Commonwealth University Medical Center Richmond, Virginia | Caleb Bridgman - (Caleb.Bridgwater@vcuhealth.org) |
| Walter Reed Military Medical Center Bethesda, Maryland | Heather Decot - (heather.k.decot.ctr@health.mil) |
| _University of California, San Francisco San Francisco, California | Eleni Berhaneselase - (eleni.berhaneselase@ucsf.edu) |
Improving Communication and Adherence in Black Breast Cancer Survivors (SIS) (SISTERS)
Cummings, Yvonne - yvonne.cummings@vcuhealth.org
Sheppard, Vanessa, B.
NCT05334732
HM20016396
Breast
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Cummings, Yvonne - (yvonne.cummings@vcuhealth.org) |
Clofazimine - Single Patient, Expanded Access
Lessard, Margaret "Meg" - margaret.lessard@vcuhealth.org
Schechter, Michael, S
19468
HM20024709
drug: Clofazimine
Diseases of Respiratory System (460-519), Infectious and Parasitic Diseases (001-139)
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Lessard, Margaret "Meg" - (margaret.lessard@vcuhealth.org) |
CIMR Neuromuscular Research Biobank (NRB-0001)
Nicholas Johnson - nicholas.johnson@vcuhealth.org
NCT05434572
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Inclusion Criteria:
* Willing and able to give informed consent
* Positive diagnosis or suspected diagnosis of neuromuscular disease, or
* Family history of neuromuscular disease, or
* Healthy volunteer
* Age Neonates-75
Exclusion Criteria:
* Unwilling to sign consent Neuromuscular Diseases, Neuromuscular Disorder, Neuromuscular Diseases in Children
Neuromuscular, Research Repository, Biobank, Neuromuscular Disorder
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Carino Jennings - (carino.garza@vcuhealth.org) |
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
Angie Lee - angie.lee@stryker.com
NCT03072927
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Inclusion Criteria:
* Medicare beneficiaries receiving MILD or interspinous process decompression
* Diagnosis of LSS with NC
Exclusion Criteria:
* Patients that have received a laminectomy, laminotomy, fusion, interspinous process decompression, or MILD in the lumbar region during the 12 months prior to the index date DEVICE: MILD, DEVICE: Interspinous Process Decompression
Lumbar Spinal Stenosis
Lumbar Spinal Stenosis, Interspinous process decompression, MILD, Medicare, Medicare Advantage
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Show 2390 locations
Study Locations
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| Location | Contacts |
|---|---|
| 877-446-6724 Bayonne, New Jersey | |
| AA Spine & Pain Clinic Anchorage, Alaska | |
| AABP Brooklyn, New York | |
| AHCMG Sugery Center Germantown Germantown, Wisconsin | |
| AHN Grove City Grove City, Pennsylvania | |
| AMITA Health Adventist Medical Center Hinsdale Hinsdale, Illinois | |
| AMITA Health St. Alexius Medical Center Hoffman Estates Hoffman Estates, Illinois | |
| AMITA St. Francis Hospital Evanston, Illinois | |
| AOS Surgery Center Augusta, Georgia | |
| APAC Surgery Center, II Crown Point, Indiana | |
| ASC For Pain Relief, LLC Evansville, Indiana | |
| ASC at St. Francis Colorado Springs, Colorado | |
| Abilene Ctr For Ortho and Multi Abilene, Texas | |
| Abilene Spine and Joint Surgery Center Abilene, Texas | |
| Abington Memorial Hospital Abington, Pennsylvania | |
| Abington Surg Ctr Willow Grove, Pennsylvania | |
| Access Surgery Center Egg Harbor, New Jersey | |
| Acute & Chronic Pain and Spine Center Ambulatory Surgery Center Amarillo, Texas | |
| Adena Greenfield Medical Center Greenfield, Ohio | |
| Adena Health System Chillicothe, Ohio | |
| Adena Pike Medical Center Waverly, Ohio | |
| Adirondack Health Saranac Lake, New York | |
| Advance Spine Ctr of Wisconsin Neenah, Wisconsin | |
| Advance Surg Instu of Evansville Evansville, Indiana | |
| Advanced Ambulatory Surgery Center Chicago, Illinois | |
| Advanced Asc Altamonte Springs, Florida | |
| Advanced Interventional Pain Katy, Texas | |
| Advanced Interventional Pain Surg Hot Springs, Arkansas | |
| Advanced Joint and Spine Instu Orlando, Florida | |
| Advanced Pain Institute Treatment Center Hammond, Louisiana | |
| Advanced Pain Institute of Texas Lewisville, Texas | |
| Advanced Pain Management Rancho Mirage, California | |
| Advanced Pain Management and Wellness Center Jupiter, Florida | |
| Advanced Pain Medicine Assocs Wichita, Kansas | |
| Advanced Pain Mgmt Lutherville-Timonium, Maryland | |
| Advanced Pain Mgmt Spclsts Fort Myers, Florida | |
| Advanced Pain Modalities Chandler, Arizona | |
| Advanced Pain Solutions Fresno, California | |
| Advanced Regional Surgery Center, LLC Jeffersonville, Indiana | |
| Advanced Spine and Outpatient Surgery Center West Orange, New Jersey | |
| Advanced Spine and Pain North Valley Phoenix, Arizona | |
| Advanced Spine and Pain Specialists Spring, Texas | |
| Advanced Surg Ctr At Brownwood The Villages, Florida | |
| Advanced Surg Ctr of El Paso El Paso, Texas | |
| Advanced Surg Ctr of Northern Utah Logan, Utah | |
| Advanced Surg Inst of New Albany New Albany, Indiana | |
| Advanced Surgery Center Omaha, Nebraska | |
| Advanced Surgery Center Omaha, Nebraska | |
| Advanced Surgery Center of Coral Gables Coral Gables, Florida | |
| Advanced Surgery Center of Lancaster Lancaster, Pennsylvania | |
| Advanced Surgery Center of San Antonio, LLC San Antonio, Texas | |
| Advanced Surgery Center of Sarasota LLC Sarasota, Florida | |
| Advanced Surgical Care of Boerne Boerne, Texas | |
| Advanced Surgical Care of Clearwater Clearwater, Florida | |
| Advanced Surgical Care of Maryland Lanham, Maryland | |
| Advanced Surgical Center of Sunset Hills St Louis, Missouri | |
| Advanced Surgical Institute Sewell, New Jersey | |
| Advanced Surgl Care of Ocala Ocala, Florida | |
| Advancedcare Surg Ctr Ennis, Texas | |
| Advent Health Ottawa Ottawa, Kansas | |
| AdventHealth Central Texas Killeen, Texas | |
| AdventHealth GlenOaks Glendale Heights, Illinois | |
| AdventHealth Orlando Orlando, Florida | |
| AdventHealth Orlando Orlando, Florida | |
| AdventHealth Pain Medicine Orlando Orlando, Florida | |
| Adventhealth Heart Of Florida Davenport, Florida | |
| Adventhealth Sebring Sebring, Florida | |
| Adventhealth Surg Ctr Wellswood Tampa, Florida | |
| Adventist Bolingbrook Hospital Bolingbrook, Illinois | |
| Adventist Glenoaks Hospital Glendale Heights, Illinois | |
| Adventist Health St Helena St. Helena, California | |
| Adventist Hlthcr Surg Ctr At Natl Oxon Hill, Maryland | |
| Adventist Medical Glendale Glendale, California | |
| Advocate Christ Medical Center Oak Lawn, Illinois | |
| Advocate Condell Medical Center Libertyville, Illinois | |
| Advocate Good Shepard Hospital Barrington, Illinois | |
| Advocate Sherman Hospital Elgin, Illinois | |
| Aiken Regional Medical Center Aiken, South Carolina | |
| Ainsworth Surgery Center Garden City, New York | |
| Alabama Ortho Spine and Sports Birmingham, Alabama | |
| All City Family Healthcare Center Brooklyn, New York | |
| Allcity Family Hlthcr Ctr Brooklyn, New York | |
| Allegheny Surgery Center Altoona, Pennsylvania | |
| Allen County Hospital Iola, Kansas | |
| Allen Memorial Hosp Waterloo, Iowa | |
| Alleviate Pain and Spine De Pere, Wisconsin | |
| Alleviate Pain and Spine - De Pere De Pere, Wisconsin | |
| Alleviate Pain and Spine - Neenah Neenah, Wisconsin | |
| Alliance Covington Covington, Georgia | |
| Alliance Specialty Surgery Center Ormond Beach, Florida | |
| Alliance Spine and Pain Peachtree City, Georgia | |
| Alliance Spine and Pain Ctrs Marietta, Georgia | |
| Alliance Spine and Pain Ctrs Marietta, Georgia | |
| Alliance Spine and Pain Ctrs Marietta, Georgia | |
| Alliance Spine and Pain Ctrs Marietta, Georgia | |
| Alliance Spine and Pain Ctrs Marietta, Georgia | |
| Alliance Spine and Pain Ctrs Marietta, Georgia | |
| Alliance Spine and Pain Ctrs Marietta, Georgia | |
| Alliance Spine and Pain Ctrs Marietta, Georgia | |
| Alliance Spine and Pain Ctrs Marietta, Georgia | |
| Alliance Surg Ctr At Johns Creek Suwanee, Georgia | |
| Alliance Surgery Center, Inc Fullerton, California | |
| Allied Physicians Surg Ctr South Bend, Indiana | |
| Alpha Surgery Center Tomball, Texas | |
| Alton Memorial Hospital Alton, Illinois | |
| Altus Baytown Hospital Baytown, Texas | |
| Altus Houston Hospital Houston, Texas | |
| Altus Pasadena Surgical Center Pasadena, Texas | |
| Am Surg Ctr Colton, California | |
| Amb Pain and Disability Mgmt Ctr Jersey City, New Jersey | |
| Amb Surg Ctr of Stockton Stockton, California | |
| Ambulatory Surgery Center Tampa, Florida | |
| Ambulatory Surgery Center LLC Oshkosh, Wisconsin | |
| Ambulatory Surgery Center of Bala Cynwyd Bala-Cynwyd, Pennsylvania | |
| Ambulatory Surgery Center of Killeen Killeen, Texas | |
| Ambulatory Surgery Center of Spartanburg Spartanburg, South Carolina | |
| Ambulatory Surgical Center of New Jersey, LLC Edison, New Jersey | |
| Ambulatory Surgical Center of Somerset Bridgewater, New Jersey | |
| Ambulatory Surgical Institute of Dallas Addison, Texas | |
| Ambulatory Surgical Pavilion at Robert Wood Johnson New Brunswick, New Jersey | |
| Ambulatory Surgical Pavilion of New Jersey Hammonton, New Jersey | |
| Amc Cavazos - Pa Cavazos, Texas | |
| American Surgical Centers West Bloomfield, Michigan | |
| Ames Surgery Center Ames, Iowa | |
| Amherst Surgery Center Amherst, New York | |
| Amita Health Resurrection Med Ctr Chicago, Illinois | |
| Amita Health St Joseph Hosp Chicago, Illinois | |
| Anderson Hospital Maryville, Illinois | |
| Anderson Regional Health System Meridian, Mississippi | |
| Anderson Regional Medical Center Meridian, Mississippi | |
| Anderson Regional Medical Center, South Campus Meridian, Mississippi | |
| Anderson Surgery Center Edwardsville, Illinois | |
| Anesis Pain- Bel-Red ASC Bellevue, Washington | |
| Ann Arbor Surgl Ctr Ann Arbor, Michigan | |
| Anne Arundel Med Ctr Pavsadena Pasadena, Maryland | |
| Apex Pain and Wellness Foster City, California | |
| Apex Spine Institute ASC Richland, Washington | |
| Apex Surgery Center Ada, Oklahoma | |
| Apex Surgical Center Westmoreland, New York | |
| Apex Surgl Ctr Royal Oak, Michigan | |
| Apogee Outpatient Surgery Center Redding, California | |
| Apollo Surg Ctr Lancaster, California | |
| Apollo Surgery Center West Melbourne, Florida | |
| Apple Valley Outpatient Surgical Center Apple Valley, California | |
| Ardmore Regional Surgery Center Ardmore, Oklahoma | |
| Arizona Pain Specialists, LLC Tempe, Arizona | |
| Arizona Pain Treatment Center Phoenix, Arizona | |
| Arizona Pain Treatment Center Phoenix, Arizona | |
| Arizona Specialty Surgery Center Chandler, Arizona | |
| Arizona Surgical Specialists Center Tempe, Arizona | |
| Arizona Surgical Specialists Center Tempe, Arizona | |
| Arizona Surgl Spclsts Ctr Scottsdale, Arizona | |
| ArkLaMiss Surgery Center, LLC Monroe, Louisiana | |
| Arkansas Surg Hosp North Little Rock, Arkansas | |
| Armenia Ambulatory Surgery Center Tampa, Florida | |
| Armenia Ambulatory Surgery Center Tampa, Florida | |
| Arnot Ogden Hospital Elmira, New York | |
| Arrowhead North Surgery Center Peoria, Arizona | |
| Artesia General Hospital Artesia, New Mexico | |
| Asc of Boca Raton Boca Raton, Florida | |
| Ascension NE Wisconsin - Mercy Hospital Oshkosh, Wisconsin | |
| Ascension NE Wisconsin - St. Elizabeth Hospital Appleton, Wisconsin | |
| Ascension St John Hospital - Detroit Detroit, Michigan | |
| Ascension St. John Hospital Health Center at 23 Mile Macomb, Michigan | |
| Ascension Via Christi St. Francis Wichita, Kansas | |
| Ascent Surg Ctr Colorado Springs, Colorado | |
| Ascentist Leawood, Kansas | |
| Ashtabula County Medical Center Ashtabula, Ohio | |
| Aspen Surgery Center Simi Valley, California | |
| Aspire Rural Health System Marlette Marlette, Michigan | |
| Associated Surgical Center Arlington Heights, Illinois | |
| Associated Surgical Center of Dearborn Dearborn Heights, Michigan | |
| Athens Orthopedic Clinic (Loganville ASC) Loganville, Georgia | |
| Athens-Limestone Hospital Athens, Alabama | |
| Atlanta Ctr For Ent Atlanta, Georgia | |
| Atlanta Outpatient Surg Ctr Atlanta, Georgia | |
| Atlantic Coast Pain Specialists Conway, South Carolina | |
| Atlantic General Hospital Berlin, Maryland | |
| Atlantic Surgery Center West Islip, New York | |
| Atlantic Surgery Center West Islip, New York | |
| Atlas Pain Spcltsts Glendale, Arizona | |
| Atlas Surg Ctr Buffalo, New York | |
| Atrium Health Pineville Charlotte, North Carolina | |
| Atrium Medical Center Middletown, Ohio | |
| Auburn Community Hospital Auburn, New York | |
| Auburn Surgery Center Cape Girardeau, Missouri | |
| Audubon Surgery Center Colorado Springs, Colorado | |
| Augusta Health Fishersville, Virginia | |
| Augusta Pain Center Augusta, Georgia | |
| Augusta University Medical Center Augusta, Georgia | |
| Aultman Alliance Community Hospital Alliance, Ohio | |
| Aultman Health Foundation Canton, Ohio | |
| Aultman Orville Orrville, Ohio | |
| Aurora BayCare Medical Center Green Bay, Wisconsin | |
| Aurora Baycare Medical Center-Discovery Green Bay, Wisconsin | |
| Aurora Germantown Germantown, Wisconsin | |
| Aurora Health Care Southern Lakes, Inc Mount Pleasant, Wisconsin | |
| Aurora Health Care Southern Lakes, Inc. Waukesha, Wisconsin | |
| Aurora Health Care Southern Lakes, Inc.- Elkhorn Elkhorn, Wisconsin | |
| Aurora Health Center 84 South Greenfield, Wisconsin | |
| Aurora Health Center Southern Lakes Burlington, Wisconsin | |
| Aurora Health Fond Du Lac Fond du Lac, Wisconsin | |
| Aurora Med Ctr Wauwatosa, Wisconsin | |
| Aurora Medical Center Kenosha Kenosha, Wisconsin | |
| Aurora Medical Center Oshkosh Oshkosh, Wisconsin | |
| Aurora St Lukes Med Ctr Milwaukee, Wisconsin | |
| Aurora St Lukes Medical Center Milwaukee, Wisconsin | |
| Aurora St Lukes South Shore Cudahy, Wisconsin | |
| Aurora Surgery Centers LLC Greenfield, Wisconsin | |
| Austin Oral Surg Pflugerville, Texas | |
| Avalon Surgery and Robotic Center Glendale, California | |
| Aventura Hospital and Medical Center Aventura, Florida | |
| Avicenna Surgery Center The Bronx, New York | |
| B3 Medical Wesley Chapel, Florida | |
| Babcock Surgical Center San Antonio, Texas | |
| Bacon County Hospital Alma, Georgia | |
| Baldwin County Surg Ctr Fairhope, Alabama | |
| Banner - University Medical Center Tucson Tucson, Arizona | |
| Banner Enticare Tempe Surgery Center Tempe, Arizona | |
| Banner Estrella Surg Ctr Phoenix, Arizona | |
| Banner Health Surgicenter Phoenix, Arizona | |
| Banner Payson Medical Center Payson, Arizona | |
| Banner Sun City West Surgery Center, LLC Sun City West, Arizona | |
| Banner Surg Ctr Biltmore Phoenix, Arizona | |
| Banner Surg Ctr Desert Vista Scottsdale, Arizona | |
| Banner Surgery Center Tucson, Arizona | |
| Banner Surgery Center - Central Phoenix Phoenix, Arizona | |
| Banner Surgery Center - Desert Mesa, Arizona | |
| Banner Surgery Center - Mesa Mesa, Arizona | |
| Banner Surgery Center - Peoria Peoria, Arizona | |
| Banner University Medical Center South Tucson, Arizona | |
| Baptist Health Louisville Louisville, Kentucky | |
| Baptist Health Medical Center - Little Rock Little Rock, Arkansas | |
| Baptist Health South Florida Miami, Florida | |
| Baptist Health Surgery Center, LLC Lexington, Kentucky | |
| Baptist Hospital of Miami Miami, Florida | |
| Baptist Med Ctr Yazoo Yazoo City, Mississippi | |
| Barclay Surg Ctr Rochester Hills, Michigan | |
| Barnes Jewish Hospital - North St Louis, Missouri | |
| Barnes Jewish Hospital South St Louis, Missouri | |
| Barnes Jewish N Hospital St Louis, Missouri | |
| Barnes-Jewish Hospital St Louis, Missouri | |
| Barnes-Jewish West County Hospital St Louis, Missouri | |
| Barnes-Jewish West County Hospital St Louis, Missouri | |
| Barrington Pain and Spine Institute LLC Barrington, Illinois | |
| Bass Surgery Center Walnut Creek, California | |
| Bassett Hlthcr Network Cooperstown, New York | |
| Baxter Regional Medical Center Mountain Home, Arkansas | |
| Bay Ridge Med Care Brooklyn, New York | |
| Bayfront Health St. Petersburg St. Petersburg, Florida | |
| Bayfront Venice Reg Surgery Venice, Florida | |
| Baylor College of Medicine Med Ctr Houston, Texas | |
| Baylor Scott & White College Station Hospital College Station, Texas | |
| Baylor Scott & White Medical Center - Marble Falls Marble Falls, Texas | |
| Baylor Scott & White Medical Center Sunnyvale Sunnyvale, Texas | |
| Baylor Scott & White Surgical Hospital at Fort Worth Fort Worth, Texas | |
| Baylor Scott & White Surgicare North Dallas Dallas, Texas | |
| Baylor Scott & White Surgicare at Plano Alliance Plano, Texas | |
| Baylor Scott and White Med Ctr McKinney, Texas | |
| Baylor Scott and White Pain Clinic Temple, Texas | |
| Baylor Scott and White Surgicare Dallas, Texas | |
| Baylor Surgicare at Fort Worth Fort Worth, Texas | |
| Bayonne Medical Center Bayonne, New Jersey | |
| Bayshore Hospital Holmdel, New Jersey | |
| Baystate Medical Center Springfield, Massachusetts | |
| Baystate Medical Center - Holyoke Holyoke, Massachusetts | |
| Baystate Pain Management Center Springfield, Massachusetts | |
| Baytown Hospital Baytown, Texas | |
| Baytown Medical Center Baytown, Texas | |
| Bayview Surgery Center Sarasota, Florida | |
| Beach Cities Orthopedic Surgery Center Manhattan Beach, California | |
| Beachwood Medical Center Beachwood, Ohio | |
| Beacon Surgery Center Lee's Summit, Missouri | |
| Beacon West Surg Ctr Leawood, Kansas | |
| Bear Creek Surg Ctr Keller, Texas | |
| Belleair Surgery Center Ltd Clearwater, Florida | |
| Bellevue Medical Center Bellevue, Nebraska | |
| Bellevue Surgery Center Bellevue, Washington | |
| Bellin Memorial Hospital Green Bay, Wisconsin | |
| Belpre Distribution Ctr Belpre, Ohio | |
| Beltway Surg Ctr Indianapolis, Indiana | |
| Bend Surgery Center Bend, Oregon | |
| Berkshire Medical Center Pittsfield, Massachusetts | |
| Berlin Interventional Pain Management Berlin, Maryland | |
| Beth Ambulatory Surgery Center Boynton Beach, Florida | |
| Beth Israel Deaconess - Plymouth Plymouth, Massachusetts | |
| Beth Israel Deaconess Hospital Needham, Massachusetts | |
| Beth Israel Deaconess Medical Center Boston, Massachusetts | |
| Beth Israel Med Ctr Phillips Amb New York, New York | |
| Bethel Park Surgery Center Bethel Park, Pennsylvania | |
| Bethesda North Hospital Cincinnati, Ohio | |
| Bethesda Orthopedic Surgery Center Cincinnati, Ohio | |
| Bethesda Outpatient Surgery Center West Palm Beach, Florida | |
| Bingham Memorial Hospital Blackfoot, Idaho | |
| Biohealth Surgl Instu Santa Monica, California | |
| Birmingham Surgery Center Birmingham, Alabama | |
| Black Hills Surgical Hospital Rapid City, South Dakota | |
| Bloomfield Hills Surgical Center Bloomfield Hills, Michigan | |
| Bloomfield Surgi-Center Bloomfield, New Jersey | |
| Blount Mem Hosp Maryville, Tennessee | |
| Blue Ridge Surgery Center Salem, Virginia | |
| Blue Ridge Surgery Center Salem, Virginia | |
| Blue Water Surgery Center Port Huron, Michigan | |
| Blue Water Surgery Center FL Port Saint Lucie, Florida | |
| Bluffton Okatie Outpatient Center Okatie, South Carolina | |
| Boca Raton Regional Boca Raton, Florida | |
| Boca Raton Surgery Center Boca Raton, Florida | |
| Body Balance Chiropractic and Wellness Houston, Texas | |
| Bone & Joint Surgical Suites Sebring, Florida | |
| Boynton Beach Ambulatory Surgery Center Boynton Beach, Florida | |
| Bozeman Outpatient Surgery Center Bozeman, Montana | |
| Bradenton Surgery Center Dublin, Ohio | |
| Brandon Ambulatory Surgery Center Brandon, Florida | |
| Brandon Surg Ctr Brandon, Florida | |
| Brandywine Hospital Coatesville, Pennsylvania | |
| Brecksville Surgery Brecksville, Ohio | |
| Briarcliff Surgery Center Kansas City, Missouri | |
| Bridgewater Ambulatory Surgery Center Bridgewater, New Jersey | |
| Brigham & Womens Hospital Boston, Massachusetts | |
| Brigham and Women's Faulkner Hospital Boston, Massachusetts | |
| Brigham and Women's Foxborough Foxborough, Massachusetts | |
| Brigham and Women's Hospital Boston, Massachusetts | |
| Brigham and Women's-Mass General Health Care Center Foxborough, Massachusetts | |
| Brighton Ctr Specialty Care Brighton, Michigan | |
| Bristol Regional Medical Center Bristol, Tennessee | |
| Broadwest Specialty Surgical Center, LLC Merrillville, Indiana | |
| Brodstone Memorial Hospital Superior, Nebraska | |
| Brooke Army Medical Center San Antonio, Texas | |
| Brookings Ambulatory Surgery Center Brookings, South Dakota | |
| Brooklyn Surgery Center Brooklyn, New York | |
| Brooklyn VA Medical Center Brooklyn, New York | |
| Broward Specialty Surgical Center Hollywood, Florida | |
| Brunswick Pain Treatment Center Brunswick, Georgia | |
| Brunswick Surgery Center Leland, North Carolina | |
| Bryn Mawr Orthopedic Surgery Center Bryn Mawr, Pennsylvania | |
| Bsmh Youngstown St Elizabeth Youngstown, Ohio | |
| Bucks County Surgical Suites Warrington, Pennsylvania | |
| Bucks County Surgl Suites Highpoint Chalfont, Pennsylvania | |
| Bucyrus Hospital Bucyrus, Ohio | |
| Bullhead City Community Hosp Bullhead City, Arizona | |
| Burbank Spine and Pain Surgery Center Burbank, California | |
| Burke Health Pain Management Waynesboro, Georgia | |
| Burlington Asc Hainesport, New Jersey | |
| Burnside Surgery Center Gresham, Oregon | |
| Butler County Health Care Center David City, Nebraska | |
| Bux Pain Management Lexington, Kentucky | |
| CGH Medical Center Sterling, Illinois | |
| CHI Health St. Francis Grand Island, Nebraska | |
| CHI St. Joseph Health Outpatient Surgery Center Lexington, Kentucky | |
| CHRISTUS Good Shepherd Medical Center - Longview Longview, Texas | |
| CHRISTUS Southeast Texas -St. Elizabeth Beaumont, Texas | |
| CVVCA Business, LLC Pine Bluff, Arkansas | |
| Cabell Huntington Hospital Huntington, West Virginia | |
| Cache Valley Surg Ctr Logan, Utah | |
| Calabasas Surgery Center Calabasas, California | |
| Calais Regional Hospital Calais, Maine | |
| California Pacific Med Ctr Mission San Francisco, California | |
| California Specialty Surgery Center Mission Viejo, California | |
| Camden Clark Medical Center Parkersburg, West Virginia | |
| Camis, Llc Eatontown, New Jersey | |
| Cancer Treatment Ctrs of America At Newnan, Georgia | |
| Canyon Surgl Ctr Mesa, Arizona | |
| Cape Coral Surg Ctr Cape Coral, Florida | |
| Cape Regional Medical Center Cape May Court House, New Jersey | |
| Capital City Surgery Center Raleigh, North Carolina | |
| Capital Health Med Ctr Hopewell Pennington, New Jersey | |
| Capital Spine and Pain Ctrs Reston, Virginia | |
| Capital Surgical Ctr Baton Rouge, Louisiana | |
| Capitol Pain Institute Austin, Texas | |
| Capitol Pain Instu Louisville, Kentucky | |
| Capitol Street Surgery Center Indianapolis, Indiana | |
| Capitol Surgical Center Bethesda, Maryland | |
| Carepath Injury Ctr of Pennsylvania Allentown, Pennsylvania | |
| Carl R Darnall Army Med Ctr Fort Cavazos, Texas | |
| Carle BroMenn Medical Center Normal, Illinois | |
| Carle Champaign Surgicenter Champaign, Illinois | |
| Carle Foundation Hosp Urbana, Illinois | |
| Carle Foundation Hosp Urbana, Illinois | |
| Carle Foundation Hosp Urbana, Illinois | |
| Carle Foundation Hospital Urbana, Illinois | |
| Carlsbad Surgery Center Carlsbad, California | |
| CaroMont Regional Medical Center Gastonia, North Carolina | |
| CarolinaEast Medical Center New Bern, North Carolina | |
| Caromount Partners Llc Dba Belmont, North Carolina | |
| Carris Health Rice Mem Hosp Willmar, Minnesota | |
| Carroll County Memorial Hospital Carrollton, Missouri | |
| Carrollton Reg Med Ctr Carrollton, Texas | |
| Carson Tahoe Regional Healthcare Carson City, Nevada | |
| Carson Tahoe Regional Medical Center Carson City, Nevada | |
| Carteret General Hospital Morehead City, North Carolina | |
| Cascade Spine Center Tualatin, Oregon | |
| Cascade Surg Ctr Bend, Oregon | |
| Castle Hills Surgicare Carrollton, Texas | |
| Castle Rock Adventist Hosp Castle Rock, Colorado | |
| Castle Surg Ctr Southlake, Texas | |
| Castleview Hospital Price, Utah | |
| Cataract Center of East Texas Tyler, Texas | |
| Catholic Medical Center Manchester, New Hampshire | |
| Catskill Regional Medical Center Harris, New York | |
| Cayuga Medical Center at Ithaca Ithaca, New York | |
| Cedar Crest Surg Ctr Allentown, Pennsylvania | |
| Cedar Park Surgery Center Cedar Park, Texas | |
| Centegra Hosp McHenry McHenry, Illinois | |
| Centeno-Schultz Clinic Broomfield, Colorado | |
| Center For Minimally Invasive Surgery Mokena, Illinois | |
| Center for Advanced Surgery Ladson, South Carolina | |
| Center for Pain Management Ambulatory Surgery Center-Sartell Sartell, Minnesota | |
| Center for Pain Management Ambulatory Surgery, LLC Alexandria, Minnesota | |
| Center for Pain Medicine and Surgery Center Fargo, North Dakota | |
| Center for Southside Surgery, LLC Greenwood, Indiana | |
| Center for Special Surgery Indianapolis, Indiana | |
| Center for Specialized Surgery LP Bethlehem, Pennsylvania | |
| Center for Specialty Surgery of Austin Austin, Texas | |
| Center for Spine Interventions ASC, LLC (ASC3) Acworth, Georgia | |
| Center for Sports Medicine and Orthopaedics Ambulatory Surgery Center Chattanooga, Tennessee | |
| Centerpoint Pain and Spine Georgetown, Kentucky | |
| Centers For Pain Solutions Nashua, New Hampshire | |
| CentraCare - Willmar Surgery Center Willmar, Minnesota | |
| CentraCare Health Monticello Monticello, Minnesota | |
| CentraCare Plaza Saint Cloud, Minnesota | |
| Central Arkansas Surgery Center Little Rock, Arkansas | |
| Central Arkansas Vetrns Hlthcr Syst Little Rock, Arkansas | |
| Central Baptist Hospital Lexington, Kentucky | |
| Central Coast Surg Ctr Freedom, California | |
| Central Florida Endoscopy and Surgical Institute of Ocala Ocala, Florida | |
| Central Florida Spine & Pain Melbourne, Florida | |
| Central Jersey Surgery Center, LLC Eatontown, New Jersey | |
| Central Kentucky Surgery Center Danville, Kentucky | |
| Central Oregon Surg Ctr Bend, Oregon | |
| Central Oregon Surgical Institute Bend, Oregon | |
| Central Texas Day Surgery Center Killeen, Texas | |
| Central Valley Surg Ctr Santa Barbara, California | |
| Centrum Surgical Center Greenwood, Colorado | |
| Centurion Surgery Center of Jacksonville Jacksonville, Florida | |
| Chandler Surgical Ctr PLC Chandler, Arizona | |
| Charles Regional Surgery Center La Plata, Maryland | |
| Charleston Area Med Ctr Teays Hurricane, West Virginia | |
| Charlie Norwood Va Med Ctr Augusta, Georgia | |
| Charlotte Surgery Center Charlotte, North Carolina | |
| Chase Gardens Surgery Center Eugene, Oregon | |
| Chattanooga Pain Surgery Center Hixson, Tennessee | |
| Chesapeake Urology Holy Cross Germantown, Maryland | |
| Chestnut Hill Hospital Philadelphia, Pennsylvania | |
| Chi St Lukes Health Patience Med Pasadena, Texas | |
| Chico Surgery Center Chico, California | |
| Chilton Mem Hosp Pompton Plains, New Jersey | |
| Chippenham Hospital Richmond, Virginia | |
| Christian Hospital St Louis, Missouri | |
| Christiana Surgicenter Newark, Delaware | |
| Christus Mother Frances Hospital Sulphur Springs, Texas | |
| Christus Physicians Ambulatory Surgery Center New Braunfels, Texas | |
| Christus Santa Rosa Hosp Alamo San Antonio, Texas | |
| Christus Santa Rosa Hosp Westover San Antonio, Texas | |
| Christus Schumpert Highland Shreveport, Louisiana | |
| Christus St Michael Health System Texarkana, Texas | |
| Christus Surgery Center at Olympia Hills Universal City, Texas | |
| Citizens Medical Center Victoria, Texas | |
| Citizens Memorial Hospital Bolivar, Missouri | |
| Clark Regional Medical Center Winchester, Kentucky | |
| Clay Surgery Center Orange Park, Florida | |
| Clear Creek Surgery Center Wheat Ridge, Colorado | |
| Clearview Eye Surgery Center Vincennes, Indiana | |
| Clearway Pain Solutions Waldorf, Maryland | |
| Clearway Pain Solutions Waldorf, Maryland | |
| Clearway Pain Solutions Waldorf, Maryland | |
| Clearway Pain Solutions Waldorf, Maryland | |
| Clearway Pain Solutions Waldorf, Maryland | |
| Clearway Pain Solutions Waldorf, Maryland | |
| Clearway Pain Solutions Waldorf, Maryland | |
| Clearway Pain Solutions Waldorf, Maryland | |
| Clearway Pain Solutions Waldorf, Maryland | |
| Clearway Pain Solutions Waldorf, Maryland | |
| Clearway Pain Solutions Waldorf, Maryland | |
| Clearway Pain Solutions - Bel Air Bel Air, Maryland | |
| Clearway Pain Solutions - Bethesda Bethesda, Maryland | |
| Clearway Pain Solutions - Columbia Columbia, Maryland | |
| Clearway Pain Solutions - Easton Easton, Maryland | |
| Clearway Pain Solutions - Salisbury Salisbury, Maryland | |
| Clearway Pain Solutions - Westminster Westminster, Maryland | |
| Clearway Pain Solutions - White Marsh Nottingham, Maryland | |
| Clearway Pain Solutions California California, Maryland | |
| Clearway Pain Solutions Largo Upper Marlboro, Maryland | |
| Clearway Pain Solutions Timonium Lutherville-Timonium, Maryland | |
| Clearway Surgery Center - Prince Frederick Prince Frederick, Maryland | |
| Clearway Surgery Center - WALDORF ASC Waldorf, Maryland | |
| Cleveland Clinic - Avon Hospital Avon, Ohio | |
| Cleveland Clinic - Pain Management Cleveland, Ohio | |
| Cleveland Clinic - Twinsburg Family Health & Surgery Center Twinsburg, Ohio | |
| Cleveland Clinic of Weston Weston, Florida | |
| Clifton Springs Hospital & Clinic Clifton Springs, New York | |
| Clifton Surgery Center, Inc Clifton, New Jersey | |
| Cmnty Hosp Oklahoma City, Oklahoma | |
| Cmnty Hosp Oklahoma City, Oklahoma | |
| Cmps Surg Ctr Daly City, California | |
| Coast Surgery Center of South Bay Torrance, California | |
| Coastal A.S.C, LLC Carlsbad, California | |
| Coastal Carolina Hospital Hardeeville, South Carolina | |
| Coastal Surgery Center Santa Barbara, California | |
| Coastal Surgery Center Santa Barbara, California | |
| Colonial Outpatient Surgery Center LLC Fort Myers, Florida | |
| Colorado Premier Surgery Center at Greenwood Village Greenwood Village, Colorado | |
| Columbia Pain Management, PC Milwaukie, Oregon | |
| Columbus Community Hosp Columbus, Texas | |
| Colusa Med Ctr Colusa, California | |
| Community Medical Center Toms River, New Jersey | |
| Community Memorial Hosp Hamilton, New York | |
| Community Surgery Center East Indianapolis, Indiana | |
| Complete Spine and Pain Care Framingham, Massachusetts | |
| Complete Surgery Center Northwest Houston, Texas | |
| Comprehensive Pain Ctr of Madison, Mississippi | |
| Comprehensive Pain Management Center Fresno, California | |
| Comprehensive Pain Management Center- St Charles Surgical Center Thousand Oaks, California | |
| Comprehensive Spine Institute Clearwater, Florida | |
| Concourse Diagnostic & Surgical Center City of Industry, California | |
| Connecticut Surgery Center Farmington, Connecticut | |
| Conway Ambulatory Surgery Center Conway, Arkansas | |
| Cookeville Regional Medical Center (N Washington Ave) Cookeville, Tennessee | |
| Cool Springs Surgery Center LLC Franklin, Tennessee | |
| Cooper Univ Hlthcr Moorestown Cmps Moorestown, New Jersey | |
| Copper Basin Surg Ctr Wasilla, Alaska | |
| Copper Ridge Surgery Center Traverse City, Michigan | |
| Coral Desert Surgery Center LLC St. George, Utah | |
| Coral Gables Hospital Miami, Florida | |
| Coral Gables Surgery Center Miami, Florida | |
| Coral Ridge Outpatient Center Oakland Park, Florida | |
| Corewell Health William Beaumont University Hospital Royal Oak, Michigan | |
| Cornell Surgery Center Beaverton, Oregon | |
| Coronado Surgery Center Sierra Vista, Arizona | |
| Coryell Health Gatesville, Texas | |
| Country Side Surgical Ctr Clearwater, Florida | |
| Court Street Surgery Center Redding, California | |
| Courtyard Surgery Pavilion Visalia, California | |
| Crater Lake Surgery Center Medford, Oregon | |
| Crossings Surgery Center Warwick, Rhode Island | |
| Crossroads Surgery Center Brentwood, Tennessee | |
| Crystal Outpatient Surgery Center Houston, Texas | |
| Crystal Run Healthcare ASC Middletown, New York | |
| Ctr For Advanced Surgical Spclsts Tampa, Florida | |
| Ctr For Ortho Surg Van Nuys, California | |
| Ctr For Pain Mgmt Bemidji, Minnesota | |
| Ctr For Spine Interventions Dallas, Georgia | |
| Ctr For the Surgl Arts Altoona, Pennsylvania | |
| Ctr for Spine and Pain Medicine Dalton, Georgia | |
| Cumberland Valley Surg Ctr Corbin, Kentucky | |
| Cushing Memorial Hospital Leavenworth, Kansas | |
| Cypress Ambulatory Surgery Center Santa Maria, California | |
| Cypress Creek Outpatient Surgical Center Fort Lauderdale, Florida | |
| DCR Surgery Center Centerville, Ohio | |
| DLJT Management Services, LLC Las Vegas, Nevada | |
| DLP Rutherford Regional Health System Rutherfordton, North Carolina | |
| Dallas County Hospital Perry, Iowa | |
| Dallas Medical Center Dallas, Texas | |
| Dameron Hospital Stockton, California | |
| Davenport Ambulatory Surgery Center Davenport, Florida | |
| David Grant USAF Medical Center Travis Air Force Base, California | |
| Davis Medical Center Elkins, West Virginia | |
| Day Op Center of Long Island Mineola, New York | |
| Day Op Ctr of Long Island Woodbury, New York | |
| Day Surg Ctr Winter Haven, Florida | |
| Day Surgery Center Charleston, West Virginia | |
| Dcr Surgery Center, Llc Centerville, Ohio | |
| De Witt Cmnty Hosp De Witt, Iowa | |
| DeTar Hospital North Victoria, Texas | |
| Deaconess Gateway Newburgh, Indiana | |
| Deaconess Henderson Hospital Henderson, Kentucky | |
| Deaconess Main Evansville, Indiana | |
| Dearborn Surgery Center Dearborn, Michigan | |
| Deca Health Toledo, Ohio | |
| Decatur Ambulatory Surgery Center Decatur, Alabama | |
| Deer Creek Surgery Center Chico, California | |
| Deer River Hlthcare Ctr Deer River, Minnesota | |
| Delaware Outpatient Center for Surgery Newark, Delaware | |
| Delmarva Pain Newark, New York | |
| Delmarva Spine and Pain Berlin, Maryland | |
| Delray Beach Surgery center Delray Beach, Florida | |
| Delray Beach Surgical Suites Delray Beach, Florida | |
| Delta Bay Surgery Center, LLC Benicia, California | |
| Deschutes Surgery Center Bend, Oregon | |
| Desert Pain Spclsts Rancho Mirage, California | |
| Desert Valley Hospital Victorville, California | |
| Detroit Receiving Hospital Detroit, Michigan | |
| District Surg Ctr Bethesda, Maryland | |
| Doctors Hospital Columbus, Ohio | |
| Doctors Hospital Columbus, Ohio | |
| Doctors Hospital of Laredo Laredo, Texas | |
| Doctors Medical Center Modesto Modesto, California | |
| Doctors Outpatient Center for Surgery: DOCS Los Angeles, California | |
| Doctors Outpatient Surgery Center Lincoln, Nebraska | |
| Doctors Outpatient Surgery Center, LLC Lafayette, Louisiana | |
| Doctors United Surgery Center Pasadena, Texas | |
| Door County Memorial Hospital Sturgeon Bay, Wisconsin | |
| Downtown Surgery Center Orlando, Florida | |
| Drexel Town Square Surg Ctr Menomonee Falls, Wisconsin | |
| Drs Same Day Surg Ctr Marrero, Louisiana | |
| Dry Creek Surgery Center Englewood, Colorado | |
| Dublin Surgery Center Dublin, Ohio | |
| Duly Surg Ctr Lombard Lombard, Illinois | |
| Duncan Regional Hospital Duncan, Oklahoma | |
| Dupage Medical Group Pain Management Surgical Center Naperville, Illinois | |
| ECMC Hospital Buffalo, New York | |
| ECU Health Beaufort Hospital Washington, North Carolina | |
| EPC Surgery Center La Mesa, California | |
| Eagle Highlands Surgery Center Indianapolis, Indiana | |
| East Ann Arbor Amb Surg and Med Ann Arbor, Michigan | |
| East Brunswick Surgery Center East Brunswick, New Jersey | |
| East Coast Surgery Center Daytona Beach, Florida | |
| East Cooper Medical Center Mt. Pleasant, South Carolina | |
| East Houston Medical Center Houston, Texas | |
| East Mequon Surgery Center Mequon, Wisconsin | |
| East Norriton Surgical Center East Norriton, Pennsylvania | |
| East Orange Gen Hosp East Orange, New Jersey | |
| East Portland Surgery Center Portland, Oregon | |
| Eastern Long Island Hospital Greenport, New York | |
| Eastern Oklahoma Va Health Care Muskogee, Oklahoma | |
| Eastwind Surgical LLC Westerville, Ohio | |
| Eaton Rapids Med Ctr Eaton Rapids, Michigan | |
| Edgar County Hospital Paris, Illinois | |
| Edgerton Hospital and Health Services Edgerton, Wisconsin | |
| Edgewood Surgical Hospital Transfer, Pennsylvania | |
| Edison Surgery Center, LLC Edison, New Jersey | |
| Edward Hospital Naperville, Illinois | |
| Edwardsville Ambulatory Surgery Center LLC Glen Carbon, Illinois | |
| Effingham Amb Surg Ctr Effingham, Illinois | |
| Einstein Medical Center Montgomery East Norriton, Pennsylvania | |
| El Paso Center for GI El Paso, Texas | |
| El Paso Specialty Hospital El Paso, Texas | |
| Elkridge Ambulatory Surgery Center Elkridge, Maryland | |
| Ellenville Regional Hospital Ellenville, New York | |
| Ellicott City Ambulatory Surgery Center Ellicott City, Maryland | |
| Elliot Hospital Manchester, New Hampshire | |
| Embassy Surgery Center Lancaster, California | |
| EmergeOrtho-Smithfield Smithfield, North Carolina | |
| Emory Decatur Hosp Decatur, Georgia | |
| Emory Johns Creek Johns Creek, Georgia | |
| Emory University Hospital Atlanta, Georgia | |
| Empire State Ambulatory Surgical Center The Bronx, New York | |
| Encino Outpatient Surg Ctr Encino, California | |
| Encore Surg Ctr Covina, California | |
| Englewood Cliffs Surg Ctr Englewood Cliffs, New Jersey | |
| Englewood Surgery Center Englewood, Colorado | |
| Enhance Center for Interventional Spine and Sports Livonia, Michigan | |
| Enloe Medical Center Chico, California | |
| Ephraim McDowell James B Haggin Hospital Hardinsburg, Kentucky | |
| Ephraim McDowell Regional Medical Center Danville, Kentucky | |
| Erie Shores Surg Ctr Sandusky, Ohio | |
| Essentia Health - Duluth Duluth, Minnesota | |
| Essentia Health Virginia Virginia, Minnesota | |
| Evans Procedure Center,LLC Evans, Georgia | |
| Evanston Hospital Northshore University Health System Evanston, Illinois | |
| Evanston Regional Hospital Evanston, Wyoming | |
| Everett Road Surgery Center Albany, New York | |
| Evolve Restorative Center Petaluma, California | |
| Executive Ambulatory Surgical Center Dearborn, Michigan | |
| Executive Surg Ctr of Little Rock Little Rock, Arkansas | |
| Executive Surgery Center Tomball, Texas | |
| F.F. Thompson Hospital Canandaigua, New York | |
| FHN Memorial Hospital Freeport, Illinois | |
| FSA of Huntingdon Valley, LLC Huntingdon Valley, Pennsylvania | |
| Fairbanks Memorial Hospital Fairbanks, Alaska | |
| Fairfax Surgical Ctr Fairfax, Virginia | |
| Fairfield Hospital Fairfield, Ohio | |
| Fairfield Surgery Center Fairfield, Connecticut | |
| Fairview UMN Health Minneapolis, Minnesota | |
| Faith Regional Health Services Norfolk, Nebraska | |
| Faith Regional Surgery Center Norfolk, Nebraska | |
| Falconhead Surgery Center Austin, Texas | |
| Family Health West Hospital Fruita, Colorado | |
| Fellowship Surgery Center Mount Laurel, New Jersey | |
| Fifth Avenue Surgery Center New York, New York | |
| First Choice Asc San Antonio, Texas | |
| First Coast Surgery Center Jacksonville, Florida | |
| FirstHealth Moore Regional Hospital Pinehurst, North Carolina | |
| Fisher-Titus Medical Center Norwalk, Ohio | |
| Fishkill Ambulatory Surgery Center Fishkill, New York | |
| Fitzgibbon Memorial Hospital Marshall, Missouri | |
| Flaget Memorial Hospital Bardstown, Kentucky | |
| Flagler Surgery Center Saint Augustine, Florida | |
| Fletcher Allen Hlthcr Williston, Vermont | |
| Florida Hospital Zephyrhills Zephyrhills, Florida | |
| Florida Pain Management Associates, PA Sebastian, Florida | |
| Florida Physical Medicine St. Petersburg, Florida | |
| Florida Specialty Surgery Center St. Petersburg, Florida | |
| Florida Springs Surg Ctr Spring Hill, Florida | |
| Flowood Surgery Center, LLC Flowood, Mississippi | |
| Folsom Surgery Center Folsom, California | |
| Foothill Reg Med Ctr Tustin, California | |
| Forbes Hosp Monroeville, Pennsylvania | |
| Forest Health Medical Center Ypsilanti, Michigan | |
| Forest Health Medical Center of Bucks County Langhorne, Pennsylvania | |
| Fort Hamilton Hospital Hamilton, Ohio | |
| Fort Lauderdale Heart and Rhythm Fort Lauderdale, Florida | |
| Fort Lauderdale Pain Medicine Fort Lauderdale, Florida | |
| Fort Sutter Surgery Center Sacramento, California | |
| Foundation Hospital San Antonio, Texas | |
| Fountain Point Surgery Center Norfolk, Nebraska | |
| Franciscan Health Dyer Dyer, Indiana | |
| Franciscan Health Michigan City Michigan City, Indiana | |
| Franciscan St Francis Health Indianapolis, Indiana | |
| Frank R Howard Mem Hosp Willits, California | |
| Frankfort Regional Medical Center Frankfort, Kentucky | |
| Franklin County Hosp Preston, Idaho | |
| Franklin Memorial Hospital Farmington, Maine | |
| Freedom Surgical Center, LLC Bloomfield, New Jersey | |
| Freeman Health System Joplin, Missouri | |
| Fremont Surg Ctr Fremont, California | |
| Fresno Surgical Hospital Fresno, California | |
| Froedtert Integrated Svc Menomonee Falls, Wisconsin | |
| Frontenac Surgery and Spine Center Frontenac, Missouri | |
| Fullerton Kimble Med Ctr Chicago, Illinois | |
| GA Interventional Pain, LLC Lawrenceville, Georgia | |
| GA Interventional Pain- F, LLC Roswell, Georgia | |
| GA Interventional Pain-B, LLC Braselton, Georgia | |
| GA Interventional Pain-C, LLC Cumming, Georgia | |
| GA Interventional Pain-D, LLC Decatur, Georgia | |
| GA Interventional Pain-E, LLC Canton, Georgia | |
| GA Interventional Pain-G, LLC Dalton, Georgia | |
| GA Interventional Pain-H, LLC Carrollton, Georgia | |
| GA Interventional Pain-I, LLC Rome, Georgia | |
| GA Interventional Pain-J, LLC Stockbridge, Georgia | |
| GA Interventional Pain-K, LLC Conyers, Georgia | |
| GA Interventional Pain-L, LLC Athens, Georgia | |
| Gabay and Gottlief Cosmetic Surg Ct Philadelphia, Pennsylvania | |
| Galileo Surgery Center San Luis Obispo, California | |
| Galion Community Hospital Galion, Ohio | |
| Gamma Surgery Center Pittsburgh, Pennsylvania | |
| Gardendale Surgical Center Gardendale, Alabama | |
| Gateway Surgical Center El Paso, Texas | |
| Geisinger Med Ctr Muncy Muncy, Pennsylvania | |
| Geisinger Saint Lukes Hospital Orwigsburg, Pennsylvania | |
| Gemini Surgery Center Columbus, Ohio | |
| Genesis Hosp Zanesville, Ohio | |
| Genesis Medical Center Davenport, Iowa | |
| Genesis Surgery Center Lansing, Michigan | |
| Genesys Surgery Center LLC Westland, Michigan | |
| Geneva Surgical Suites LLC Genoa City, Wisconsin | |
| George Washington Univ Hosp Washington D.C., District of Columbia | |
| Georgia Pain and Spine Care Newnan, Georgia | |
| Gibson Area Hosp and Health Svcs Gibson City, Illinois | |
| Gibson General Hospital Princeton, Indiana | |
| Gila Valley Procedure Center Safford, Arizona | |
| Gladiolus Surgery Center LLC Fort Myers, Florida | |
| Glasgow Surgery Center Newark, Delaware | |
| Glatz Group McAllen, Texas | |
| Glen Rose Med Ctr Glen Rose, Texas | |
| Glenwood Surge Ctr Riverside, California | |
| Global Microsurgical Ctr of Park Park City, Utah | |
| Global Surgery Center Oradell, New Jersey | |
| GoldStep Ambulatory Surgery Center, LLC Brooklyn, New York | |
| Golden Ridge Surgery Center Golden, Colorado | |
| Golden Springs Surgical Center Cathedral City, California | |
| Golden Valley Memorial Hospital Clinton, Missouri | |
| Golf Surgical Center Des Plaines, Illinois | |
| Good Samaritan Hospital Corvallis, Oregon | |
| Good Samaritan Hospital Corvallis, Oregon | |
| Good Shepherd Medical Center Hermiston, Oregon | |
| Goshen Surg Ctr Goshen, Indiana | |
| Grace Medical Center Lubbock, Texas | |
| Grace Medical Center - OP Lubbock, Texas | |
| Grady Health System Atlanta, Georgia | |
| Grady Memorial Hosp Chickasha, Oklahoma | |
| Graham Hosp Canton, Illinois | |
| Graham Hospital Canton, Illinois | |
| Gramercy Surgery Center Flushing, New York | |
| Granbury Hosp Corp Granbury, Texas | |
| Grand Avenue Surg Ctr Los Angeles, California | |
| Grand Island Regional Medical Center Grand Island, Nebraska | |
| Grand Island Surgery Center Grand Island, Nebraska | |
| Grand Rapids Surgical Suites Grand Rapids, Michigan | |
| Grand Valley Surgical Center Grand Rapids, Michigan | |
| Grand View Surgery Center at Harleysville Harleysville, Pennsylvania | |
| Granville Medical Center Oxford, North Carolina | |
| Great Lakes Pain Management Willoughby Hills, Ohio | |
| Great Lakes Surgical Center Southfield, Michigan | |
| Great Plains Regional Medical Center Elk City, Oklahoma | |
| Greater Erie Surgery Center Erie, Pennsylvania | |
| Greater Erie Surgery Center, LLC Erie, Pennsylvania | |
| Greensboro Specialty Surgical Center Greensboro, North Carolina | |
| Greenview Surg Ctr Bowling Green, Kentucky | |
| Greenwich Village Ambulatory Surgery Center New York, New York | |
| Griffin Ctr For Pain and Spine Griffin, Georgia | |
| Grove Place Surgery Center Vero Beach, Florida | |
| Gulf Pointe Surgery Center Port Charlotte, Florida | |
| Gundersen Lutheran Medical Center La Crosse, Wisconsin | |
| Gwinnett Med Ctr Lawrenceville, Georgia | |
| HHC Southington Surgery Center, LLC, DBA Cheshire Surgery Center Cheshire, Connecticut | |
| Habana Ambulatory Surgery Center Tampa, Florida | |
| Hackensack Musculoskeletal Surg Ctr Hackensack, New Jersey | |
| Hackensack Surgery Center, LLC Hackensack, New Jersey | |
| Halifax Regional Medical Center, Inc. Roanoke Rapids, North Carolina | |
| Hallandale Outpatient Surgical Center Hallandale, Florida | |
| Hamilton Amb Surg Ctr Dalton, Georgia | |
| Hamilton Gen Hosp Hamilton, Texas | |
| Hamilton Med Ctr Dalton, Georgia | |
| Hamilton Surgery Center Hamilton, New Jersey | |
| Hanover Hills Surgery Center LLC Florham Park, New Jersey | |
| Hanover Parkway Surgery Center Greenbelt, Maryland | |
| Harbor Heights Surg Ctr Oxon Hill, Maryland | |
| Harborside Surg Ctr Oxon Hill, Maryland | |
| Harmony Surgery Center Fort Collins, Colorado | |
| Harrison County Community Hospital Bethany, Missouri | |
| Harrison Endo Surgical Center Harrison, New Jersey | |
| Harrison Memorial Hospital Cynthiana, Kentucky | |
| Hartford Hospital Hartford, Connecticut | |
| Hattiesburg Clinic Hattiesburg, Mississippi | |
| Hauppauge SC Hauppauge, New York | |
| Havasu Surgery Center Lake Havasu City, Arizona | |
| Hawthorn Surgery Center Vernon Hills, Illinois | |
| Hayden Surgical Center Scottsdale, Arizona | |
| Haymarket Surgery Center Haymarket, Virginia | |
| Hays Med Ctr Hays, Kansas | |
| Hays Surgery Center Kyle, Texas | |
| Hca Houston Hlthcr Northwest Houston, Texas | |
| Headache and Pain Ctr New Iberia, Louisiana | |
| Headache and Pain Ctr New Iberia, Louisiana | |
| Healdsburg District Hospital Healdsburg, California | |
| Health East ASC Englewood, New Jersey | |
| Healthsouth Sunrise Rehab Hospital Sunrise, Florida | |
| Heart of America Surgery Kansas City, Kansas | |
| Heartland Radiology Grand Island, Nebraska | |
| Hedrick Medical Center Chillicothe, Missouri | |
| Heights Surgical Institute Newport Beach, California | |
| Helena Surgicenter Helena, Montana | |
| Hemlock Ambulatory Surgery Center Macon, Georgia | |
| Hendrick Med Ctr South Abilene, Texas | |
| Henrico Doctors Hospital Richmond, Virginia | |
| Henry Ford Health System - Columbus Novi, Michigan | |
| Henry Ford Health System - Dearborn Dearborn, Michigan | |
| Henry Ford Health System - Royal Oak Royal Oak, Michigan | |
| Henry Ford Health System- Plymouth Plymouth, Michigan | |
| Heritage One Day Surgery North Syracuse, New York | |
| Herndon Surgery Center Fresno, California | |
| Herrin Hospital Herrin, Illinois | |
| Hershey Outpatient Surgery Center Hershey, Pennsylvania | |
| Highland District Hospital Hillsboro, Ohio | |
| Highland Medical Center Scottsboro, Alabama | |
| Highland Park Hospital Northshore University Health System Highland Park, Illinois | |
| Highline South Ambulatory Surgery Center, LLC Littleton, Colorado | |
| Hillcrest Hospital Mayfield Heights, Ohio | |
| Hinsdale Surgical Center Hinsdale, Illinois | |
| Hoboken Univ Med Ctr Hoboken, New Jersey | |
| Hocking Valley Community Hospital Logan, Ohio | |
| Hollywood Regional Surgery Center Hollywood, Florida | |
| Holy Cross Hosp Davis Layton, Utah | |
| Holy Cross Hosp Jordan Valley West West Valley City, Utah | |
| Holy Cross Hosp Pain Mgmt Oakland Park, Florida | |
| Holy Cross Hospital Fort Lauderdale, Florida | |
| Holy Cross Hospital, FTL Fort Lauderdale, Florida | |
| Holy Name Medical Center Teaneck, New Jersey | |
| Holyoke Medical Center Inc Holyoke, Massachusetts | |
| Holzer Gallipolis Gallipolis, Ohio | |
| Honolulu Spine Ctr Honolulu, Hawaii | |
| Hope Ambulatory Surgery Center Irvine, California | |
| Horizon Health Paris, Illinois | |
| Horizon Medical Center Dallas, Texas | |
| Houston Meth Cypress Hosp Cypress, Texas | |
| Houston Methodist Baytown Hospital Baytown, Texas | |
| Houston Methodist Clear Lake Hospital Nassau Bay, Texas | |
| Houston Methodist Orthopedic & Sports Medicine Houston, Texas | |
| Houston Methodist Sugar Land Hospital Sugar Land, Texas | |
| Houston Methodist Surgery Center Baytown, Texas | |
| Houston Methodist The Woodlands Hospital The Woodlands, Texas | |
| Houston Methodist Willowbrook Hospital Houston, Texas | |
| Houston Orthopedic and Spine Surgery Center Katy, Texas | |
| Houston Physicians Hospital Webster, Texas | |
| Houston Premier Surgery Center in The Villages Houston, Texas | |
| Houston Surgery Center Houston, Texas | |
| Howard County Medical Center Saint Paul, Nebraska | |
| Hoyman Hong San Mateo, California | |
| Hudson Crossing Surgery Center Fort Lee, New Jersey | |
| Hudson Medical Group New York, New York | |
| Hudson Regional Hospital Secaucus, New Jersey | |
| Hudson Surg Ctr New York, New York | |
| Humble Vascular Surgical Center Humble, Texas | |
| Humboldt General Hospital Winnemucca, Nevada | |
| Hunter Holmes McGuire VA Med Ctr Richmond, Virginia | |
| Hunterdon Center for Surgery Flemington, New Jersey | |
| Hunterdon Medical Center Flemington, New Jersey | |
| Huntington Ambulatory Surgery Center LLC Pasadena, California | |
| Huntington Hospital Huntington, New York | |
| Huron Valley Sinai Hospital Commerce, Michigan | |
| Hyde Park Same Day Surgicenter, LLC Chicago, Illinois | |
| IU Health Ball Outpatient Surgery Center Muncie, Indiana | |
| IU Health Beltway Surgery Center Carmel, Indiana | |
| IU Health East Beltway Surgery Center Indianapolis, Indiana | |
| IU Health Frankort Hospital Frankfort, Indiana | |
| IU Health Multi Specialty Surgery Center Indianapolis, Indiana | |
| IU Health Saxony Ambulatory Surgery Center Fishers, Indiana | |
| IUH University Hospital Indianapolis, Indiana | |
| Idaho Physical Medicine and Rehabilitation Meridian, Idaho | |
| Iinn Novi Novi, Michigan | |
| Illinois Back and Neck Institute Elmhurst, Illinois | |
| Illinois Sports Medicine & Orthopedic Surgery Center Morton Grove, Illinois | |
| Indian Creek Ambulatory Surgery Center Overland Park, Kansas | |
| Indian River Medical Center Vero Beach, Florida | |
| Indiana Pain Ctrs Evansville Evansville, Indiana | |
| Indiana Regional Medical Center Indiana, Pennsylvania | |
| Indiana Univ Health Methodist Med Indianapolis, Indiana | |
| Indu and Raj Soin Medical Center Beavercreek, Ohio | |
| Ingalls Same Day Surgery Tinley Park, Illinois | |
| Innovative Pain Treatment Surgery Center Temecula, California | |
| Innovative Procedural Center Watertown, South Dakota | |
| Innovative Solutions, LLC Houston, Texas | |
| Innovative Surgery Center Surprise, Arizona | |
| Inov8 Orthopedics Houston, Texas | |
| Insight Hosp and Med Ctr Coldwater Coldwater, Michigan | |
| Insight Hospital & Medical Center-Chicago Chicago, Illinois | |
| Insight Pain Management - Flint Flint, Michigan | |
| Inspira Medical Center Woodbury, New Jersey | |
| Inspira Medical Center Elmer Elmer, New Jersey | |
| Integrated Surgical Institute Leesport, Pennsylvania | |
| Intermountain Surg Ctr Tosh Salt Lake City, Utah | |
| Interventional & Surgical Suites of Wilkes - Barre, LLC Wilkes-Barre, Pennsylvania | |
| Interventional Pain Center Chesterfield - Satellite Chesterfield, Missouri | |
| Interventional Pain Center of Chesterfield Chesterfield, Missouri | |
| Interventional Pain Management Hobart, Indiana | |
| Interventional Pain Management Center Jonesboro, Arkansas | |
| Interventional Pain Management, LLC Munster, Indiana | |
| Interventional Pain Mgmt Valparaiso, Indiana | |
| Interventional Surgery Institute Little Rock, Arkansas | |
| Intracoastal Surgery Center Melbourne, Florida | |
| Ipc Dalton Asc Dalton, Georgia | |
| Ipc Surg Ctr Cleveland, Tennessee | |
| Ireland Grove Center for Surgery Bloomington, Illinois | |
| Irvine Surgical Partners, LLC Irvine, California | |
| Island Amb Surg Ctr Brooklyn, New York | |
| Island Health Hospital Anacortes, Washington | |
| Ivinson Mem Hosp Laramie, Wyoming | |
| JDS Surgical LLC Phoenix, Arizona | |
| JFK Medical Center North Campus West Palm Beach, Florida | |
| JFK Medical Center North Campus West Palm Beach, Florida | |
| Jackson General Hospital Ripley, West Virginia | |
| Jackson Surgical Center Jackson, New Jersey | |
| Jacksonville Beach Surgery Center Jacksonville Beach, Florida | |
| Jacksonville Outpatient Surgery Center Orange Park, Florida | |
| Jacobs Med Ctr La Jolla, California | |
| James H Quillen Va Med Ctr Mountain Home, Tennessee | |
| Jasper Ambulatory Surgical Center Brick, New Jersey | |
| Jefferson Methodist Hospital Philadelphia, Pennsylvania | |
| Jefferson Surgery Center Sewell, New Jersey | |
| Jefferson Surgery Center-Cherry Hill Cherry Hill, New Jersey | |
| Jefferson Surgical Center at the Navy Yard Philadelphia, Pennsylvania | |
| Jefferson Washington Twp Hosp Turnersville, New Jersey | |
| Jennie Edmundson Memorial Hospital Council Bluffs, Iowa | |
| Jersey City Medical Center Jersey City, New Jersey | |
| Jersey Shore Ambulatory Surgery Center Somers Point, New Jersey | |
| Jewett Orthopedic Institute Surgery Center Orlando, Florida | |
| Jewish Hospital - Mercy Health Cincinnati, Ohio | |
| John Peter Smith Hosp Fort Worth, Texas | |
| John T Mather Memorial Hospital Port Jefferson, New York | |
| Johns Hopkins Bayview Medical Center Baltimore, Maryland | |
| Johns Hopkins Enterprise Baltimore, Maryland | |
| Johns Hopkins Enterprise Baltimore, Maryland | |
| Johns Hopkins Health Care & Surgery Center - Bethesda Bethesda, Maryland | |
| Johns Hopkins Howard County Operating Room Columbia, Maryland | |
| Johns Hopkins Surg Ctrs Series Lutherville-Timonium, Maryland | |
| Johns Hopkins Surgery Center- White Marsh Nottingham, Maryland | |
| Johns Hopkins Surgery Centr- Howard County Columbia, Maryland | |
| Johnston Health Smithfield, North Carolina | |
| Johnston Willis Hosp Richmond, Virginia | |
| Johnston Willis Hospital North Chesterfield, Virginia | |
| Jonesboro Ambulatory Surgery Center, LLC Jonesboro, Arkansas | |
| Jordan Valley Hosp West Jordan, Utah | |
| Jordan Valley Med Ctr West Valley West Valley City, Utah | |
| JourneyLite of Cincinnati Cincinnati, Ohio | |
| Jupiter Med Ctr Jupiter, Florida | |
| Jupiter Outpatient Surgery Center Jupiter, Florida | |
| KU MedWest Shawnee Mission, Kansas | |
| Kaiser Permanente San Francisco, California | |
| Kaiser Permanente Fresno Medical Center Fresno, California | |
| Kaiser Permanente Richmond Medical Center Richmond, California | |
| Kaiser Permanente San Jose San Jose, California | |
| Kaiser Permanente Santa Rosa Med Santa Rosa, California | |
| Kansas City Orthopedic Institute Leawood, Kansas | |
| Kansas Spine & Specialty Hospital Wichita, Kansas | |
| Kansas Surgery & Recovery Center Wichita, Kansas | |
| Kansas Surgery Center Overland Park, Kansas | |
| Katherine Shaw Bethea Hospital Dixon, Illinois | |
| Kearney County Health Services Minden, Nebraska | |
| Kearney Pain Treatment Center Kearney, Nebraska | |
| Keck Medicine of USC Los Angeles, California | |
| Kennedy White Surg Ctr Sarasota, Florida | |
| Kentuckiana Medical Center Clarksville, Indiana | |
| Kentucky Surgery Center Lexington, Kentucky | |
| Kettering Health Dayton Dayton, Ohio | |
| Kimel Park Surgery Center Winston-Salem, North Carolina | |
| Kings Daughters Med Ctr Brookhaven, Mississippi | |
| Kings Daughters Medical Center Ashland, Kentucky | |
| Knoxville Spine Surg Ctr Knoxville, Tennessee | |
| Kokomo Ambulatory Surgery Center Kokomo, Indiana | |
| Koman Family Outpatient Pavilion La Jolla, California | |
| Kumar Surgical Center Rochester Hills, Michigan | |
| Kw Neurospine Miami, Florida | |
| Ky Advanced Surgical Center, Inc. Fresno, California | |
| La Veta Surgical Center Orange, California | |
| Lafayette Gen Surgl Hosp Lafayette, Louisiana | |
| Lafayette Pain Care Lafayette, Indiana | |
| Lafayette Pain Care Lafayette, Indiana | |
| Lafayette Surgery Center Lafayette, Indiana | |
| Laguna Surgery Center Fullerton, California | |
| Lahey Clinic Burlington Burlington, Massachusetts | |
| Lahey Health Info Techlgy Ctr Woburn, Massachusetts | |
| Lahey Outpatient Center - Danvers Danvers, Massachusetts | |
| Lake Charles Memorial Hospital Lake Charles, Louisiana | |
| Lake City Surg Ctr Lake City, Florida | |
| Lake County Pain & Diagnostic Center LLC Mentor, Ohio | |
| Lake Drive Surgical Center Grand Rapids, Michigan | |
| Lake Health TriPoint Medical Center Concord, Ohio | |
| Lake Health West Med Ctr Willoughby, Ohio | |
| Lake Mary Surgery Center Lake Mary, Florida | |
| Lake Worth Surgical Center Lake Worth, Florida | |
| Lakeside Surgery Center Omaha, Nebraska | |
| Lakeview Reg Med Ctr Covington, Louisiana | |
| Lakewalk Surgery Center Duluth, Minnesota | |
| Lakewood Surgery Center Lakewood, New Jersey | |
| Lancaster Gen Health Lancaster, Pennsylvania | |
| Lancaster Specialty Surgery Center Lancaster, Ohio | |
| Langhorne Surgical Center Langhorne, Pennsylvania | |
| Lankenau Medical Center Wynnewood, Pennsylvania | |
| Lansdale Hospital Lansdale, Pennsylvania | |
| Laredo Medical Center Laredo, Texas | |
| Largo Medical Center Upper Marlboro, Maryland | |
| Larkin Community Hospital South Miami, Florida | |
| Laser And Surgery Center Palm Beach Gardens, Florida | |
| Laser Surgery Center Tempe, Arizona | |
| Laser Surgery Center-Tempe Tempe, Arizona | |
| Laservue Eye Center Santa Rosa, California | |
| Lees Summit Medical Center Lee's Summit, Missouri | |
| Legent Institute of Specialized Surgery Conroe, Texas | |
| Legent North Houston Surgical Hospital Tomball, Texas | |
| Legent Orthopedic Hospital Carrollton, Texas | |
| Legent Orthopedic and Spine San Antonio, Texas | |
| Legent Outpatient Surgery Austin Austin, Texas | |
| Legent Westover Hills Surgery Center San Antonio, Texas | |
| Lehigh Valley Hosp Dickson City Dickson City, Pennsylvania | |
| Lehigh Valley Hospital - Cedar Crest Allentown, Pennsylvania | |
| Lehigh Valley Hospital - Hecktown Easton, Pennsylvania | |
| Lehigh Valley Hospital - Muhlenberg Bethlehem, Pennsylvania | |
| Lehigh Valley Hospital-Carbon Lehighton, Pennsylvania | |
| Lehigh Valley Hospital-Schuylkill Pottsville, Pennsylvania | |
| Lenox Health Greenwich Village New York, New York | |
| Lenox Hill Hosp New York, New York | |
| Leonardtown Surg Ctr Leonardtown, Maryland | |
| Lewis Gale Hospital Salem, Virginia | |
| Lexington Clinic Asc Lexington, Kentucky | |
| Lexington Surgery Center Lexington, Kentucky | |
| Liberty Hospital Liberty, Missouri | |
| Lincoln Surgery Center Parker, Colorado | |
| Linden Oaks Surgery Center Rochester, New York | |
| Lindenhurst Surgery Center Lindenhurst, Illinois | |
| Little Company of Mary Hospital Evergreen Park, Illinois | |
| Little Rock Surgery Center Little Rock, Arkansas | |
| Logan Regional Medical Center Logan, West Virginia | |
| Loma Linda University Medical Center Loma Linda, California | |
| Loma Linda University Medical Center Loma Linda, California | |
| Lompoc Valley Medical Center Lompoc, California | |
| Long Island Community Hospital Patchogue, New York | |
| Longview Reg Med Ctr Longview, Texas | |
| Lorain Surgery Center Lorain, Ohio | |
| Los Angeles County and Univ of Los Angeles, California | |
| Louisiana Pain Care Monroe, Louisiana | |
| Loyola Ambulatory Surgery Center at Oakbrook Oakbrook Terrace, Illinois | |
| Lubbock Surg Ctr Lubbock, Texas | |
| Lvc Surg Ctr Las Vegas, Nevada | |
| Lynbrook Surg Ctr Lynbrook, New York | |
| MALO Center for Ambulatory Surgery Rutherford, New Jersey | |
| MAO Leawood Surgery Center, LLC Leawood, Kansas | |
| MD Pain Care, PC Conyers, Georgia | |
| MHSC Woodlands Parkway The Woodlands, Texas | |
| MT Ogden Surg Ctr Ogden, Utah | |
| MUSC Health Columbia Medical Center Downtown Columbia, South Carolina | |
| MUSC Rutledge Tower Charleston, South Carolina | |
| Madison Spine Surg Ctr Flowood, Mississippi | |
| Madison Surgery Center Madison, Wisconsin | |
| Magna Surgical Cente Bedford Park, Illinois | |
| Maimonides Midwood Community Hospital Brooklyn, New York | |
| Main Line Spine Surgery Center King of Prussia, Pennsylvania | |
| Manalapan Surgery Center Manalapan, New Jersey | |
| Manchester Surgery Center Whiting, New Jersey | |
| Manchester Surgery Center Whiting, New Jersey | |
| Manhattan Surgery Center New York, New York | |
| Mankato Clinic Ltd Mankato, Minnesota | |
| Maplewood Ambulatory Surgery Center Wichita Falls, Texas | |
| Margaret R. Pardee Memorial Hospital Hendersonville, North Carolina | |
| Marin Specialty Surgery Center San Rafael, California | |
| Marion Med Cmps Marion, Ohio | |
| Marion Surgery Center LLC Ocala, Florida | |
| Marlette Reg Hosp Marlette, Michigan | |
| Marshfield Clinic Health System Marshfield, Wisconsin | |
| Marshfield Clinic-Minocqua Minocqua, Wisconsin | |
| Maryland Specialty Surgery Center Linthicum Heights, Maryland | |
| Mason City Surgery Center Mason City, Iowa | |
| Massachusetts Gen Hosp Boston, Massachusetts | |
| Matrix Surgery Center Saginaw, Michigan | |
| Mayo Clinic Rochester, Minnesota | |
| Mayo Clinic Rochester, Minnesota | |
| Mayo Clinic Health System Menomonie, Wisconsin | |
| Mayo Clinic Health System In Mankato, Minnesota | |
| Mayo Clinic Health System Northland Barron, Wisconsin | |
| Mayo Clinic Health System- La Crosse La Crosse, Wisconsin | |
| Mayo Clinic Health System-Eau Claire Eau Claire, Wisconsin | |
| Mays and Schnapp Neurospine and Memphis, Tennessee | |
| McLaren Hospital - Lapeer Lapeer, Michigan | |
| McLeod Seacoast OR Little River, South Carolina | |
| Mckenzie County Hlthcr Systems Watford City, North Dakota | |
| Meadowview Regional Medical Center Maysville, Kentucky | |
| Meadville Medical Center Meadville, Pennsylvania | |
| Med Univ Hosp Autg Charleston, South Carolina | |
| MedStar Franklin Square Medical Center Rosedale, Maryland | |
| MedStar Franklin Square Medical Center Rosedale, Maryland | |
| MedStar Georgetown University Hospital Washington D.C., District of Columbia | |
| MedStar Good Samaritan Hospital Baltimore, Maryland | |
| MedStar Harbor Hospital Baltimore, Maryland | |
| MedStar Health Harbor Hospital Baltimore, Maryland | |
| MedStar Health at Lafayette Center Washington D.C., District of Columbia | |
| MedStar Montgomery Medical Center Olney, Maryland | |
| MedStar Southern Maryland Hospital Center Clinton, Maryland | |
| MedStar St. Mary's Hospital Leonardtown, Maryland | |
| MedStar Union Memorial Hospital Baltimore, Maryland | |
| MedStar Union Memorial Hospital Baltimore, Maryland | |
| Medford Surg Ctr Medford, Massachusetts | |
| Medical Arts Surgery Center at South Miami South Miami, Florida | |
| Medical City Surgery Center Southlake Southlake, Texas | |
| Medical Education and Research Institute Memphis, Tennessee | |
| Medstar Surg Ctr At Annapolis Annapolis, Maryland | |
| Medstar Washington Hospital Center Washington D.C., District of Columbia | |
| Melbourne Surgery Center Melbourne, Florida | |
| Mem Hermann Cypress Hosp Cypress, Texas | |
| Mem Hermann Southeast Hosp Houston, Texas | |
| Mem Hermann Surg Ctr Conroe Conroe, Texas | |
| Mem Hosp Miramar Miramar, Florida | |
| Mem Hosp of Carbon County Rawlins, Wyoming | |
| Mem Pain Surg Ctr Oklahoma City, Oklahoma | |
| Memorial Ambulatory Surgery Center Houston, Texas | |
| Memorial Ambulatory Surgery Center LLC Mount Holly, New Jersey | |
| Memorial Healthcare Owosso, Michigan | |
| Memorial Herman Surg Ctr Sugar Land, Texas | |
| Memorial Hermann Specialty Hosp Kingwood, Texas | |
| Memorial Hermann Surg Ctr the Woodlands Shenandoah, Texas | |
| Memorial Hermann Surgery Center - Kingsland Katy, Texas | |
| Memorial Hermann Surgery Center - Main Street Houston, Texas | |
| Memorial Hermann Surgery Center Brazoria Angleton, Texas | |
| Memorial Hermann Surgery Center Greater Heights Houston, Texas | |
| Memorial Hermann Surgery Center Main Street Houston, Texas | |
| Memorial Hermann Surgery Center Memorial Village Houston, Texas | |
| Memorial Hermann Surgery Center North Houston Endoscopy and Surgery Houston, Texas | |
| Memorial Hermann Surgical Hospital First Colony Sugar Land, Texas | |
| Memorial Hermann West Houston Surgery Center Houston, Texas | |
| Memorial Hospital Belleville Belleville, Illinois | |
| Memorial Houston Surgery Center Houston, Texas | |
| Memorial Houston Surgery Center Houston, Texas | |
| Memorial Regional Hospital South Hollywood, Florida | |
| Memorial Same Day Surgery Center Pembroke Pines, Florida | |
| Memorial Sloan Kettering New York, New York | |
| Memorial Sloan-Kettering Cancer Center Inc New York, New York | |
| MemorialCare Surgical Center Laguna Woods Laguna Woods, California | |
| Menlo Park Surgery Center Edison, New Jersey | |
| Menorah Medical Center Overland Park, Kansas | |
| Mentor Surgery Center Mentor, Ohio | |
| Mentor Surgery Center Mentor, Ohio | |
| Mercy Anderson Asc Cincinnati, Ohio | |
| Mercy Cedar Rapids Cedar Rapids, Iowa | |
| Mercy General Hospital Sacramento, California | |
| Mercy Health Allen Hosp Oberlin, Ohio | |
| Mercy Health St Elizabeth Boardman Youngstown, Ohio | |
| Mercy Hosp Anderson Hosp Cincinnati, Ohio | |
| Mercy Hosp Lebanon Lebanon, Missouri | |
| Mercy Hospital Ardmore Ardmore, Oklahoma | |
| Mercy Hospital Carthage Carthage, Missouri | |
| Mercy Hospital Lincoln Troy, Missouri | |
| Mercy Hospital Springfield Springfield, Missouri | |
| Mercy Hospital Washington Washington, Missouri | |
| Mercy Hospital of St Louis St Louis, Missouri | |
| Mercy Med Ctr Oshkosh, Wisconsin | |
| Mercy Medical Center Springfield, Massachusetts | |
| Mercy Medical Center - Clinton Clinton, Iowa | |
| Mercy Medical Center - Des Moines Des Moines, Iowa | |
| Mercy Medical Center - North Iowa Mason City, Iowa | |
| Mercy Medical Center Mt. Shasta Mount Shasta, California | |
| Mercy Regional Medical Center Lorain, Ohio | |
| Mercy San Juan Medical Center Carmichael, California | |
| Mercy St. Charles Hospital Oregon, Ohio | |
| Mercy Surg Ctr Redding, California | |
| MercyOne Des Moines Medical Center Des Moines, Iowa | |
| Mercyone Newton Med Ctr Newton, Iowa | |
| Merritt Island Surgery Center Merritt Island, Florida | |
| Mesa Outpatient Treatment Ctr Mesa, Arizona | |
| Meth Hosp Omaha, Nebraska | |
| Methodist HealthWest Omaha, Nebraska | |
| Methodist Hospitals Northlake Gary, Indiana | |
| Methodist Hospitals Southlake Merrillville, Indiana | |
| Methodist Medical Center Oak Ridge, Tennessee | |
| Metro Health and Surgery Center Cleveland, Ohio | |
| Metro Main Campus Cleveland, Ohio | |
| MetroHealth Parma Medical Center Parma, Ohio | |
| MetroWest Medical Center - Framingham Union Hospital Framingham, Massachusetts | |
| Metrohealth West 150th Health and Cleveland, Ohio | |
| Metropolitan Surgical Institute South Amboy, New Jersey | |
| Miami Surgical Center Miami, Florida | |
| Miami Surgical Suites LLC Miami, Florida | |
| Miami Valley Ambulatory Surgery Center Dayton, Ohio | |
| Miami Valley Hospital North Dayton, Ohio | |
| Miami Valley South Hospital Centerville, Ohio | |
| Michiana Surgery Center Mishawaka, Indiana | |
| Michigan Advanced Surgical Center, PLLC Warren, Michigan | |
| Michigan Institute for Advanced Surgery Lake Orion, Michigan | |
| Michigan Neurology Associates & P.C. Clinton Township, Michigan | |
| Michigan Outpatient Surgical Solutions Novi, Michigan | |
| Mid America Surg Institute Overland Park, Kansas | |
| Mid South Pain Treatment Southaven, Mississippi | |
| MidAmerica Spine Center St Louis, Missouri | |
| MidMichigan Medical Center - West Branch West Branch, Michigan | |
| Midamerica Spine Ctr Creve Coeur, Missouri | |
| Middleburg Surgery Center Middleburg, Florida | |
| Middlesex Hospital Middletown, Connecticut | |
| Midsouth Interventional Pain Jackson, Tennessee | |
| Midtown Surgery Center New York, New York | |
| Midwest Center for Day Surgery Downers Grove, Illinois | |
| Midwest Pain Management Center Lee's Summit, Missouri | |
| Milbank Area Hosp Avera Health Milbank, South Dakota | |
| Milford Surg Ctr Milford, Connecticut | |
| Mille Lacs Hosp Onamia, Minnesota | |
| Millenia Surgery Center Orlando, Florida | |
| Millennium Surgical Center Cherry Hill, New Jersey | |
| Millman-Derr Surgicenter Rochester Hills, Michigan | |
| Mills Health Ctr San Mateo, California | |
| Milton S Hershey Medical Center Hershey, Pennsylvania | |
| Milwaukee Surgical Suites LLC Franklin, Wisconsin | |
| Minden Med Ctr Minden, Louisiana | |
| Minimally Invasive Surgery Center of New England Bedford, New Hampshire | |
| Minimally Invasive Surgical Institute Mission Viejo, California | |
| Miracle Hills Surgery Center Omaha, Nebraska | |
| Mission Advanced Pain Mgmt and Irvine, California | |
| Mission Hospital Asheville, North Carolina | |
| Mississippi Sports Medicine and Ort Flowood, Mississippi | |
| Mississippi Valley Surgery Center Davenport, Iowa | |
| Missouri Baptist Medical Center St Louis, Missouri | |
| Missouri Baptist Medical Center St Louis, Missouri | |
| Moab Regional Hospital Moab, Utah | |
| Modern Pain & Spine PC Albuquerque, New Mexico | |
| Modesto Memorial Hospital Modesto, California | |
| Monocacy Surgery Center, LLC Frederick, Maryland | |
| Monroe County Surgical Center Waterloo, Illinois | |
| Montefiore Medical Center The Bronx, New York | |
| Montefiore Mount Vernon Mount Vernon, New York | |
| Montefiore Nyack Hospital Nyack, New York | |
| Monterey Pain & Spine Institute Monterey, California | |
| Monterey Peninsula Surgery Centers Monterey, California | |
| Monterey Peninsula Surgery Centers - Munras Ave Monterey, California | |
| Montfort Surgery Center Dallas, Texas | |
| Montgomery Surgery Center Lansdale, Pennsylvania | |
| Monticello Community Surgery Center Charlottesville, Virginia | |
| Monument Health Rapid City Hospital Rapid City, South Dakota | |
| Morris County Surgical Center Parsippany, New Jersey | |
| Morristown Memorial Pain Mgmt Morristown, New Jersey | |
| Morton Hospital Taunton, Massachusetts | |
| Mount Nittany Medical Center State College, Pennsylvania | |
| Mount Sinai Medical Center Miami Beach, Florida | |
| Mount Sinai Morningside Manhattan, New York | |
| Mountain Surgery Center West Orange, New Jersey | |
| Mountain View Hosp Payson, Utah | |
| Mountain View Hospital Idaho Falls, Idaho | |
| Mountain View Surgery Center of Gilbert Gilbert, Arizona | |
| Mountain View Surgery Center of Scottsdale Scottsdale, Arizona | |
| Mountain View Surgical Center Meridian, Idaho | |
| Mountain West Med Ctr Tooele, Utah | |
| Mt. Baker Surgery Center Bellingham, Washington | |
| Munster Surg Ctr Munster, Indiana | |
| Murdock Ambulatory Surgery Center Port Charlotte, Florida | |
| Musculoskeletal Ambulatory Surgery Center Bradenton, Florida | |
| Musculoskeletal Ambulatory Surgery Centers at Coastal Orthopedics & Sports Medicine Bradenton, Florida | |
| Museum District Ambulatory Surgery Center Houston, Texas | |
| Mymichigan Med Ctr Midland Midland, Michigan | |
| NEA Baptist Clinic Jonesboro, Arkansas | |
| NH Brunswick Medical Center Bolivia, North Carolina | |
| NH Medical Park Hospital Winston-Salem, North Carolina | |
| NMSC of St. Peters City of Saint Peters, Missouri | |
| NPI Surgery Center Lincoln, Nebraska | |
| NPI Surgery Center LLC Lincoln, Nebraska | |
| NTTC Surgery Center Mesquite, Texas | |
| NYP -Methodist Hospital Brooklyn, New York | |
| NYU Ambulatory Care Center New York, New York | |
| NYU Langone ASC - Garden City Garden City, New York | |
| NYU Langone Ambulatory Care Center New York, New York | |
| NYU Langone Hospital-Long Island (Winthrop) Mineola, New York | |
| NYU Langone Orthopedic New York, New York | |
| Napa Surgery Center Napa, California | |
| Napa Valley Surgery Center Napa, California | |
| Naperville Surgery Center Naperville, Illinois | |
| Nasa Surg Ctr of Naples Naples, Florida | |
| Natick Surg Ctr Natick, Massachusetts | |
| National Pain Institute Winter Park, Florida | |
| National Pain Institute Winter Park, Florida | |
| National Pain Institute Winter Park, Florida | |
| National Pain Institute - Lady Lake Lady Lake, Florida | |
| National Pain and Spine Centers Frederick, Maryland | |
| National Spine and Ortho Surgery Center - Fort Myers Fort Myers, Florida | |
| National Spine and Pain Centers McLean, Virginia | |
| National Spine and Pain Centers McLean, Virginia | |
| National Spine and Pain Centers McLean, Virginia | |
| National Spine and Pain Centers McLean, Virginia | |
| National Spine and Pain Centers McLean, Virginia | |
| National Spine and Pain Centers McLean, Virginia | |
| National Spine and Pain Centers McLean, Virginia | |
| National Spine and Pain Centers McLean, Virginia | |
| National Spine and Pain Centers McLean, Virginia | |
| National Spine and Pain Centers McLean, Virginia | |
| National Spine and Pain Centers McLean, Virginia | |
| National Spine and Pain Centers McLean, Virginia | |
| National Spine and Pain Centers McLean, Virginia | |
| National Spine and Pain Centers McLean, Virginia | |
| National Spine and Pain Centers McLean, Virginia | |
| Natividad Medical Center Salinas, California | |
| Natl Spine and Pain Ctrs Gainesville, Georgia | |
| Nea Baptist Memorial Hosp Jonesboro, Arkansas | |
| Nebraska Medical Center Omaha, Nebraska | |
| Nebraska Pain Institute Lincoln, Nebraska | |
| Neptune Surgical Institute Neptune City, New Jersey | |
| Neurosurgery and Endovascular Associates LLC Franklin, Wisconsin | |
| Nevada Advanced Pain Spclsts Reno, Nevada | |
| Nevada Surgical Suites Las Vegas, Nevada | |
| Nevada Surgical Suites - Central Location Las Vegas, Nevada | |
| New Braunfels Surgery Center New Braunfels, Texas | |
| New Britain Surgery Center Chalfont, Pennsylvania | |
| New England Ambulatory SurgiCenter Cambridge, Massachusetts | |
| New England Baptist Hospital Boston, Massachusetts | |
| New England Center for Orthopaedic Surgery Portsmouth, New Hampshire | |
| New England Pain Care Pain and Wellness Center Peabody, Massachusetts | |
| New England Surgery Center Beverly, Massachusetts | |
| New Horizons Surgery Center Marion, Ohio | |
| New River Valley Surg Ctr Christiansburg, Virginia | |
| New York Presbyterian Allen Hospital New York, New York | |
| New York Presbyterian Hospital New York, New York | |
| New York Presbyterian Hospital New York, New York | |
| New York Prsby Lower Manhattan Hosp New York, New York | |
| Newnan Surgery Center Newnan, Georgia | |
| Newport Beach Surgery Center Newport Beach, California | |
| Newport Coast Surgery Center Newport Beach, California | |
| Newton Wellesley Hospital Ambulatory Care Center Newton, Massachusetts | |
| Nexus Pain Center Columbus, Georgia | |
| Noble Pain Management Columbia, Missouri | |
| Noble Pain Mangement Columbia, Missouri | |
| Non Surgical Orthopaedic Marietta, Georgia | |
| North American Spine & Pain Hainesport, New Jersey | |
| North Arkansas Med Ctr Harrison, Arkansas | |
| North Baldwin Infirmary Bay Minette, Alabama | |
| North Bay Regional Surgery Center Novato, California | |
| North Campus Surgery Center Creve Coeur, Missouri | |
| North Canyon Med Ctr Inc Gooding, Idaho | |
| North Carolina Specialty Hospital Durham, North Carolina | |
| North Central Baptist Hospital San Antonio, Texas | |
| North Coast Surgery Center Oceanside, California | |
| North County Surgicenter Palm Beach Gardens, Florida | |
| North Dakota Surgery Center Grand Forks, North Dakota | |
| North East Regional Surgical Center Paramus, New Jersey | |
| North East Surgery Center Scranton, Pennsylvania | |
| North Florida Surgical Pavillion Gainesville, Florida | |
| North Haven Surgery Center North Haven, Connecticut | |
| North Idaho Pain Center Coeur d'Alene, Idaho | |
| North Jersey Ortho Spclsts Teaneck, New Jersey | |
| North Kansas City Hospital Kansas City, Missouri | |
| North Naples Surgery Center Naples, Florida | |
| North Pines Surgery Center Conroe, Texas | |
| North Point Surgery Center Fresno, California | |
| North Pointe Health and Wellness Roscoe, Illinois | |
| North Pointe Surg Ctr Lebanon, Pennsylvania | |
| North Shore Surgi-Center Smithtown, New York | |
| North Shore University Evanston Hospital Evanston, Illinois | |
| North Suburban Pain and Spine Ctr Des Plaines, Illinois | |
| North Texas Surgery Center Sherman, Texas | |
| North Valley Surgery Center Scottsdale, Arizona | |
| NorthEast Surgicare, LLC Lakewood, New Jersey | |
| NorthShore University Health System Skokie, Illinois | |
| Northaven Surg Ctr Allen, Texas | |
| Northeast Ambulatory Center Stoneham, Massachusetts | |
| Northeast Georgia Surgery Center Gainesville, Georgia | |
| Northeast Regional Surgery Center Plains, Pennsylvania | |
| Northeastern Rehab Assocs Pc Moosic, Pennsylvania | |
| Northern Arizona Surgicenter Flagstaff, Arizona | |
| Northern Light Eastern Maine Medical Center Bangor, Maine | |
| Northern Light Interventional Pain Management Bangor, Maine | |
| Northern Louisiana Medical Center Ruston, Louisiana | |
| Northern Monmouth Regional Surgery Center Manalapan, New Jersey | |
| Northern Nevada Medical Center Sparks, Nevada | |
| Northern Ohio Surgery Center Beachwood, Ohio | |
| Northpoint Surgery Center West Palm Beach, Florida | |
| Northpointe Surgical Ctr Tooele, Utah | |
| Northshore Medical Center Miami, Florida | |
| Northside Hosp Cherokee Canton, Georgia | |
| Northway Surgery & Pain Center Halfmoon, New York | |
| Northwest Community Hospital Arlington Heights, Illinois | |
| Northwest Health - La Porte La Porte, Indiana | |
| Northwest Health Physicians' Specialty Hospital Fayetteville, Arkansas | |
| Northwest Medical Center Margate, Florida | |
| Northwest Specialty Hospital Post Falls, Idaho | |
| Northwest Spine and Laser Surgery Center Wilsonville, Oregon | |
| Northwest Surg Ctr Red Oak Houston, Texas | |
| Northwest Surgicare Arlington Heights, Illinois | |
| Northwestern Lake Forest Lake Forest, Illinois | |
| Northwestern McHenry Hospital McHenry, Illinois | |
| Northwestern Medicine Central Winfield, Illinois | |
| Northwestern Palos Hospital Palos Heights, Illinois | |
| Norton Audubon Hospital Louisville, Kentucky | |
| Norton Brownsboro Hospital Louisville, Kentucky | |
| Norton Healthcare Inc. Louisville, Kentucky | |
| Norton St. Matthews Louisville, Kentucky | |
| Norwalk Surgery Center Norwalk, Connecticut | |
| Novamed Surgery Center of Baton Rouge Baton Rouge, Louisiana | |
| Novant Health Matthews Med Ctr Matthews, North Carolina | |
| Novant Health Midtown Outpatient Surgery Center Charlotte, North Carolina | |
| Novant Health Presbyterian Medical Center Charlotte, North Carolina | |
| Novant Kernersville Medical Hospital Kernersville, North Carolina | |
| Novi Surgery Center Novi, Michigan | |
| Noyes Memorial Hospital Dansville, New York | |
| Nura Precision Pain Management - Edina Clinic Minneapolis, Minnesota | |
| Nuvance Health Vassar Brothers Medical Center Poughkeepsie, New York | |
| Nuvation Pain Group Buena Park, California | |
| Nyu Langone Amb Care Clinic Brooklyn, New York | |
| O'Bleness Hospital Athens, Ohio | |
| OCH Regional Medical Center Starkville, Mississippi | |
| OCOM North Oklahoma City, Oklahoma | |
| OCOM South Oklahoma City, Oklahoma | |
| OMNI Pain & Precision Medicine Clinton, New York | |
| OSF Heart of Mary Medical Center Urbana, Illinois | |
| OSF Saint Anthony Medical Center Rockford, Illinois | |
| OSF Saint Anthony Medical Center Rockford, Illinois | |
| OSF St. Joseph Medical Center Bloomington, Illinois | |
| OSS Health Powder Mill York, Pennsylvania | |
| Oak ASC, LLC Bourbonnais, Illinois | |
| Oak Brook Surg Ctr Oak Brook, Illinois | |
| Oakland Surgi Center, Inc. Rochester Hills, Michigan | |
| Oakleaf Surgical Hosp Eau Claire, Wisconsin | |
| Oakleaf Surgl Hosp Altoona, Wisconsin | |
| Ocala Regional Medical Center Ocala, Florida | |
| Ocala Surgical Ctr Ocala, Florida | |
| Ochsner Baptist Med Ctr New Orleans, Louisiana | |
| Ochsner Clearview Med Complex Metairie, Louisiana | |
| Ochsner Med Ctr Hancock Bay Saint Louis, Mississippi | |
| Ochsner St Anne Hosp Raceland, Louisiana | |
| Ohio County Hospital Hartford, Kentucky | |
| Ohio State East Hospital Columbus, Ohio | |
| Ohio Valley Hospital McKees Rocks, Pennsylvania | |
| Ohio Valley Surgical Hospital Springfield, Ohio | |
| Oil Ctr Surgl Plaza Lafayette, Louisiana | |
| Oklahoma Heart Hosp South Oklahoma City, Oklahoma | |
| Oklahoma Pain Physicians Oklahoma City, Oklahoma | |
| Oklahoma Spine Surgery Center Oklahoma City, Oklahoma | |
| Oklahoma Spine Surgery Center Oklahoma City, Oklahoma | |
| Oklahoma State University Medical Center Tulsa, Oklahoma | |
| Old Town Scottsdale Surg Ctr Scottsdale, Arizona | |
| Olean Gen Hosp Olean, New York | |
| Olmsted Med Ctr Rochester, Minnesota | |
| Olympia Surg Ctr Olympia, Washington | |
| Omaha Ambulatory Surgery Center Omaha, Nebraska | |
| Omni Surgery Center Utica, New York | |
| On Beach Surgery Center Buena Park, California | |
| One Step Diagnostic Sugar Land Sugar Land, Texas | |
| OneCore Health Oklahoma City, Oklahoma | |
| Oneonta Specialty Svcs Oneonta, New York | |
| Onslow Memorial Hospital Jacksonville, North Carolina | |
| Optimum Pain & Regenerative Medicine Harlingen, Texas | |
| Optimun Surgical Center Phoenix, Arizona | |
| Orange County Surgery Center Westminster, California | |
| Oregon Outpatient Surgery Center Tigard, Oregon | |
| Oregon Pain Center Portland, Oregon | |
| Oregon Specialists Surgery Center Salem, Oregon | |
| Oregon Surgical Institute Beaverton, Oregon | |
| Orlando Health Amb Care Ctr Orlando, Florida | |
| Orlando Health Medical Pavilion - St. Cloud Saint Cloud, Florida | |
| Orlando Orthopaedic Outpatient Surgery Center LLC Orlando, Florida | |
| Orlando Outpatient Surgery Center Orlando, Florida | |
| Orlando Regional Medical Center Orlando, Florida | |
| Orlando Regional St. Cloud Saint Cloud, Florida | |
| Oro Valley Surgical Suites Oro Valley, Arizona | |
| Oroville Hospital Oroville, California | |
| Ortho Arkansas Little Rock, Arkansas | |
| Ortho Ny Amb Surg Ctr Clifton Park, New York | |
| Ortho Surg Ctr Panther Creek Cary, North Carolina | |
| OrthoArizona Scottsdale Surgery Center Scottsdale, Arizona | |
| OrthoAtlanta Surg Ctr Aus Austell, Georgia | |
| OrthoNY Albany, New York | |
| Orthonebraska Hosp Omaha, Nebraska | |
| Orthopaedic Associates of Central Texas Surgery Center, LLC Austin, Texas | |
| Orthopaedic Surgery Center Gainesville, Florida | |
| Orthopedic Institute of Ocala Surgery Center Ocala, Florida | |
| Orthopedic Spine Care of Long Island Huntington Station, New York | |
| Orthopedic Surgery Center of Palm Beach County Boynton Beach, Florida | |
| Outpatient Procedure Ctr Wilmington, Delaware | |
| Outpatient Services East Birmingham, Alabama | |
| Outpatient Surg and Imaging Svcs Albuquerque, New Mexico | |
| Outpatient Surgery Center of Asheville Asheville, North Carolina | |
| Outpatient Surgery Center of Jonesboro Jonesboro, Arkansas | |
| Overland Park Surgery Center Lenexa, Kansas | |
| Overlook Medical Center Summit, New Jersey | |
| Owenboro Health Muhlenberg Community Hospital Greenville, Kentucky | |
| PMC Regional Hospital New Albany, Indiana | |
| PMSI - Pain Medicine Divison Pottstown, Pennsylvania | |
| PSA Ambulatory Surgical Center of Austin, LLC Austin, Texas | |
| PSA Ambulatory Surgical Center of South Austin, LLC Austin, Texas | |
| Pacific Ambulatory Surgery Center Alhambra, California | |
| Pacific Northwest Surgery Center Springfield, Oregon | |
| Pacific Restorative Center Santa Rosa, California | |
| Pacific Surg Ctr Omaha, Nebraska | |
| Pacific Surgery Center Poulsbo, Washington | |
| Pacific Surgery Center Poulsbo, Washington | |
| Pacific Surgical Institute San Diego, California | |
| Pain & Sleep Institute of Oklahoma Edmond, Oklahoma | |
| Pain Care Boise Boise, Idaho | |
| Pain Care Center of Georgia Stockbridge, Georgia | |
| Pain Center of Wyoming Valley, LLC Wilkes-Barre Township, Pennsylvania | |
| Pain Centers of Minnesota Chaska, Minnesota | |
| Pain Consultants ASC Pascagoula, Mississippi | |
| Pain Consultants of Atlanta Fayetteville, Georgia | |
| Pain Consultants of Atlanta Fayetteville, Georgia | |
| Pain Consultants of San Diego Chula Vista, California | |
| Pain Ctrs of Iowa Davenport, Iowa | |
| Pain Diagnostic and Treatment Center Sacramento, California | |
| Pain Institute of Southern Arizona Procedure Center Tucson, Arizona | |
| Pain Management Centers of America Evansville, Indiana | |
| Pain Management Specialists Rockville, Maryland | |
| Pain Management Specialists Rockville, Maryland | |
| Pain Medicine of the South Knoxville, Tennessee | |
| Pain Physician New York New York, New York | |
| Pain Physicians NY New York, New York | |
| Pain Physicians of Atlanta Alpharetta, Georgia | |
| Pain Therapy Associates Schaumburg, Illinois | |
| Pain Treatment Ctrs of America Jonesboro, Arkansas | |
| Pain, Spine & Rehab, P.A. Great Bend, Kansas | |
| PainCARE, PA Overland Park, Kansas | |
| Palm Beach Gardens Regional Surgery Center Palm Beach, Florida | |
| Palm Beach International Surgery Center at The Paley Institute West Palm Beach, Florida | |
| Palmdale Reg Med Ctr Palmdale, California | |
| Palmetto Health Toumey Sumter, South Carolina | |
| Palmetto Health USC Medical Group Columbia, South Carolina | |
| Palmetto Lakes Surgical Center Hialeah, Florida | |
| Palms West Hospital Loxahatchee Groves, Florida | |
| Palms West Surgicenter Loxahatchee Groves, Florida | |
| Palo Alto Med Foundation Fremont, California | |
| Palo Alto Med Foundation Warehouse Santa Clara, California | |
| Palo Verde Pain Specialists ASC Peoria, Arizona | |
| Palomar Surgl Ctr Escondido, California | |
| Paoli Hosp Paoli, Pennsylvania | |
| Paradigm Pain and Spine Lexington, Kentucky | |
| Paramount Surgical Center Houston, Texas | |
| Park Center Surgical Center Laurel, Maryland | |
| Park Center for Procedures Fort Myers, Florida | |
| Park Place Surgery Center Maitland, Florida | |
| Park Place Surgical Hosp Lafayette, Louisiana | |
| Park Plaza Surgical Specialists Shreveport, Louisiana | |
| ParkCreek Surgery Center Coconut Creek, Florida | |
| ParkCreek Surgery Center - Parent Coconut Creek, Florida | |
| Parkland Health Ctr Farmington Farmington, Missouri | |
| Parkridge Medical Center Chattanooga, Tennessee | |
| Parkway Ambulatory Surgery Center Lyndhurst, New Jersey | |
| Parkway Surgery Center Myrtle Beach, South Carolina | |
| Parkway Surgery Center Myrtle Beach, South Carolina | |
| Parkwest Surgical Ctr Akron, Ohio | |
| Parrish Med Ctr Titusville, Florida | |
| Pascack Valley Medical Center Westwood, New Jersey | |
| Patient Care Associates Englewood, New Jersey | |
| Peachtree Orthopedics Surgery Center Atlanta, Georgia | |
| Peak Health Surgicare of Horizon Medical Center Richardson, Texas | |
| Peak Point Midtown West Asc New York, New York | |
| Pearl Surg Ctr North Las Vegas, Nevada | |
| Pearl Womens Ctr Portland, Oregon | |
| Pekin Memorial Hospital East Peoria, Illinois | |
| Peninsula Ortho Assocs Surg Ctr Salisbury, Maryland | |
| Penn Highlands Mon Valley Monongahela, Pennsylvania | |
| Penn Med At Rittenhouse Philadelphia, Pennsylvania | |
| Penn Medicine Radnor Radnor, Pennsylvania | |
| Penn Presbyterian Med Ctr Philadelphia, Pennsylvania | |
| Peoria Foot and Ankle Spclsts Peoria, Arizona | |
| Performance Health Surgery Center Fort Myers, Florida | |
| Performance Surgical Associates Bridgewater, New Jersey | |
| Phelps County Regional Medical Center Rolla, Missouri | |
| Phelps Memorial Hospital Center Sleepy Hollow, New York | |
| Philadelphia Pain Philadelphia, Pennsylvania | |
| Philadelphia Surgi Center Philadelphia, Pennsylvania | |
| Philadelphia Surgical Center Narberth, Pennsylvania | |
| Phoenix Eye Surgical Center dba Central Phoenix Surgical Center Phoenix, Arizona | |
| Phoenix Spine and Joint Gilbert, Arizona | |
| Physician's Surgery Center of Knoxville Knoxville, Tennessee | |
| Physicians Adventist Surgery Center Glendale, California | |
| Physicians Day Surgery Naples, Florida | |
| Physicians Outpatient Surgery Center Fort Lauderdale, Florida | |
| Physicians Regional Pine Ridge Naples, Florida | |
| Physicians Surgery Center Blytheville, Arkansas | |
| Physicians Surgery Center Of Downey Downey, California | |
| Physicians Surgery Center/Jackson Jackson, Tennessee | |
| Physicians Surgical Center Lebanon, Pennsylvania | |
| Physicians West El Paso Surg Ctr El Paso, Texas | |
| Physicians' Surgery Center Prairie Village, Kansas | |
| Physicians' SurgiCenter Toms River, New Jersey | |
| Piedmont Atlanta Hosp Atlanta, Georgia | |
| Piedmont Surgery Center Greenville, South Carolina | |
| Pikeville Medical Center Pikeville, Kentucky | |
| Pinnacle Hospital Crown Point, Indiana | |
| Pinnacle Orthopaedic Surg Ctr Woodstock, Georgia | |
| Pinnacle Outpatient Surgl Instu Tempe, Arizona | |
| Pinnacle Regional Hospital Overland Park, Kansas | |
| Pinnacle Surgery Center Covington, Louisiana | |
| Pioneer Endo and Surg Ctr Sterling Heights, Michigan | |
| Pittsburg Surgical Center Pittsburg, Kansas | |
| Plastic Surgical Center of Rapid City Rapid City, South Dakota | |
| Platinum Surgery Center Harlingen, Texas | |
| Pleasantdale Ambulatory Care West Orange, New Jersey | |
| Plum Creek Surgery Center LLC Kyle, Texas | |
| Pohlman Pain Associates Delray Beach, Florida | |
| Pohlman Pain Assocs Coral Springs, Florida | |
| Point Meadows Surg Ctr Jacksonville, Florida | |
| Port Jefferson Surgery Center Port Jefferson Station, New York | |
| Portsmouth Regional Ambulatory Surgery Center Portsmouth, New Hampshire | |
| Portsmouth Regional Hospital Portsmouth, New Hampshire | |
| Potomac View Surg Ctr Llc Oxon Hill, Maryland | |
| Pottstown Hospital Pottstown, Pennsylvania | |
| Poway Surgery Center Poway, California | |
| Precision Ortho and Sports Laurel, Maryland | |
| Precision Ortho and Sports Laurel, Maryland | |
| Precision Pain care Lancaster, Ohio | |
| Precision Regenerative and Functional Medicine West Lake Hills, Texas | |
| Precision Surg Ctr Texarkana, Texas | |
| Precision Surg Ctr Texarkana, Texas | |
| Precision Surgical Center of NWA Rogers, Arkansas | |
| PrecisionCare Surgery Center East Setauket, New York | |
| Preferred Surgicenter Orland Park, Illinois | |
| Premier Endoscopy Surgery Center Gilbert, Arizona | |
| Premier Orthopaedic Surgery Center - Nashville Nashville, Tennessee | |
| Premier Outpatient Surgery Center Colton, California | |
| Premier Pain Centers Shrewsbury, New Jersey | |
| Premier Pain Professionals (Tilden Surgery Center) Pottsville, Pennsylvania | |
| Premier Pain Solutions Dallas, Texas | |
| Premier Surgery Center Brunswick, Georgia | |
| Premier Surgery Center Brunswick, Georgia | |
| Premier Surgery Center Brunswick, Georgia | |
| Premier Surgery Center of Louisville Louisville, Kentucky | |
| Premier Surgery Center of Sarasota Sarasota, Florida | |
| Premier Surgery Center/Atrium Health Wake Forest Baptist High Point, North Carolina | |
| Premier Surgical Center Marlton, New Jersey | |
| Premier Surgical Center Marlton, New Jersey | |
| Premier Surgical Center of Michigan Clinton Township, Michigan | |
| Presbyterian Medical Center Philadelphia, Pennsylvania | |
| Prescott OutPatient Surgery Center Prescott, Arizona | |
| Presence St Joseph Med Ctr Joliet, Illinois | |
| Presidio Surg Ctr San Francisco, California | |
| Preston Surg Ctr Frisco, Texas | |
| Preva Surgicare Spring, Texas | |
| Prime Surg Ctr Indianapolis, Indiana | |
| Prince Frederick Surg Ctr Prince Frederick, Maryland | |
| Prince William Surgery Center Manassas, Virginia | |
| Princeton Cmnty Hosp Princeton, West Virginia | |
| Prisma Health Outpatient Surgery Maryville, Tennessee | |
| Prisma Health-Upstate - Materials Distribution Center Simpsonville, South Carolina | |
| ProHealth Ambulatory Surgery Center New Hyde Park, New York | |
| Progress West Hospital O'Fallon, Missouri | |
| Prohealth Waukesha Mem Hosp Waukesha, Wisconsin | |
| Proliance Eastside Surgery Center Kirkland, Washington | |
| Proliance Surgery Center Renton, Washington | |
| Prosser Memorial Hospital Prosser, Washington | |
| Providence Little Company of Mary Medical Center San Pedro San Pedro, California | |
| Providence Queen of the Valley Medical Center Napa, California | |
| Providence Surgery Center Mount Juliet, Tennessee | |
| Puget Sound Pain Clinic Tukwila, Washington | |
| Quad City Ambulatory Surgery Center Moline, Illinois | |
| Quail Surgical and Pain Management Center Reno, Nevada | |
| Queen of the Valley Hosp West Covina, California | |
| RAYUS Radiology - Woodbury ASC Woodbury, Minnesota | |
| RWJ Endosurgical Center East Brunswick, New Jersey | |
| RWJ University Hospital - N Brunswick New Brunswick, New Jersey | |
| Radiance Surgery Center Bridgeville, Pennsylvania | |
| Radiance Surgery Center Bridgeville, Pennsylvania | |
| Raleigh Gen Hosp Beckley, West Virginia | |
| Raleigh General Hospital Beckley, West Virginia | |
| Raleigh Neurosurgical and Spine Surgery Center Raleigh, North Carolina | |
| Rancho Bernardo Surgery Center San Diego, California | |
| Raritan Valley Surgery Center Somerset, New Jersey | |
| Reclaimability Pain Svcs Linwood, New Jersey | |
| Red River Surg Ctr Shreveport, Louisiana | |
| Red Rock Surgery Center Las Vegas, Nevada | |
| Red Rocks Surgery Center Golden, Colorado | |
| Redlands Mesa Surgery Center Grand Junction, Colorado | |
| Redwood City Medical Center - Kaiser Permanente Redwood City, California | |
| Redwood Surgery Center Castro Valley, California | |
| Regenerative Institute of Newport Beach Newport Beach, California | |
| Regional West Medical Center Scottsbluff, Nebraska | |
| Rehabilitation Institute of Michigan Detroit, Michigan | |
| Rehabilitation Institute of Michigan Main Campus Detroit, Michigan | |
| Reid Outpatient Surgery & End Richmond, Indiana | |
| Relievus Surg Ctr of Cherry Hill Cherry Hill, New Jersey | |
| Rembrandt Outpatient Surgery Mesa, Arizona | |
| Renaissance Surgery Center Fresno, California | |
| Renown South Meadows Medical Center Reno, Nevada | |
| Restorative Surg Ctr Florissant, Missouri | |
| Revive Ortho Spne and Sports Lithia Springs, Georgia | |
| Rex HealthCare Raleigh, North Carolina | |
| Riceland Surgery Center Beaumont, Texas | |
| Richfield Surg Ctr Richfield, Utah | |
| Richmond Pain Management ASC Staten Island, New York | |
| Richmond University Medical Center Staten Island, New York | |
| Ridgefield Surgical Center Ridgefield, Connecticut | |
| Ridgeview Medical Center Waconia, Minnesota | |
| Rinehart Surgery Center Lake Mary, Florida | |
| Rio Grande Pain Team Weslaco, Texas | |
| Riva Road Surgery Center Annapolis, Maryland | |
| River City Surg Ctr Jacksonville, Florida | |
| River North Same Day Surgery Chicago, Illinois | |
| River Oaks Hospital and Clinics Houston, Texas | |
| Riverfront Surgery Center Chattanooga, Tennessee | |
| Rivers Edge Surg Ctr Rancho Mirage, California | |
| Riverside Med Ctr Kankakee, Illinois | |
| Riverside Surgical Center Jacksonville, Florida | |
| Rivertown Surgery Center Conway, South Carolina | |
| Riverview Ambulatory Surgical Center Kingston, Pennsylvania | |
| Riverview Health Crookston, Minnesota | |
| Riverview Health Institute Dayton, Ohio | |
| Riverview Medical Center Red Bank, New Jersey | |
| Riverwalk Ambulatory Surgery Center Bradenton, Florida | |
| Roane General Hospital Spencer, West Virginia | |
| Rochelle Community Hospital Rochelle, Illinois | |
| Rochester ASC Rochester, New York | |
| Rockford Ambulatory Surgery Center Rockford, Illinois | |
| Rogue Valley Surg Ctr Medford, Oregon | |
| Roseville Surgery Center Roseville, California | |
| Royal Oak Surgical Center Royal Oak, Michigan | |
| Rush Oak Brook Surgery Center Oak Brook, Illinois | |
| Rush Oak Park Hospital Oak Park, Illinois | |
| Rush SurgiCenter Chicago, Illinois | |
| Rush Univ Med Ctr Chicago, Illinois | |
| Ruxton Surgi Center Towson, Maryland | |
| SCA Danbury Surgery Center Danbury, Connecticut | |
| SCA Guilford Surgery Center Guilford, Connecticut | |
| SMART Surgery Center Arcadia, California | |
| SOG Surgery Center Tupelo, Mississippi | |
| SRMC Surg and Outpatient Pavilion Columbiana, Ohio | |
| SSM Health - St. Mary's Hospital Madison, Wisconsin | |
| SSM Health St Joseph Hospital Lake St Louis Lake Saint Louis, Missouri | |
| SSM Health St Joseph Hospital St Charles Saint Charles, Missouri | |
| SSM Health St. Mary's Hospital - Jefferson City Jefferson City, Missouri | |
| SSM St. Clare Surgical Center Fenton, Missouri | |
| STHS - Edinburg Hospital Edinburg, Texas | |
| Sacred Heart Med Park at Desitin Destin, Florida | |
| Sahara Surgery Center Las Vegas, Nevada | |
| Saint Alphonsus Medical Center Baker City Baker City, Oregon | |
| Saint Alphonsus Medical Center Boise Boise, Idaho | |
| Saint Alphonsus Medical Center Ontario Ontario, Oregon | |
| Saint Anne's Hospital: Southern New England Surgical Center Attleboro, Massachusetts | |
| Saint Francis Hospital-Bartlett Bartlett, Tennessee | |
| Saint John Hospital Leavenworth, Kansas | |
| Saint Joseph East Hospital Lexington, Kentucky | |
| Saint Joseph Lexington Lexington, Kentucky | |
| Saint Luke's Health System Overland Park, Kansas | |
| Saint Luke's Hospital of Kansas City Kansas City, Missouri | |
| Saint Luke's Northland Kansas City, Kansas | |
| Saint Luke's Pain Management Center Kansas City, Missouri | |
| Saint Luke's South Surgery Center LLC. Overland Park, Kansas | |
| Salem ASC Salem, New Jersey | |
| Salem Cmnty Hosp Salem, Ohio | |
| Salem Hospital Salem, Oregon | |
| Salinas Surgery Center Salinas, California | |
| Samaritan Endoscopy Center Los Gatos, California | |
| Samaritan Healthcare Moses Lake, Washington | |
| Samaritan Med Ctr Watertown, New York | |
| Same Day Procedures Clifton, New Jersey | |
| Same Day Surg Ctr of Central New Jersey Edison, New Jersey | |
| Same Day Surgery Center Rapid City, South Dakota | |
| Samson Pain Center (ASC) Woodstock, Georgia | |
| San Antonio Military Med Ctr San Antonio, Texas | |
| San Carlos Clinic San Carlos, California | |
| San Francisco Hospital San Francisco, California | |
| San Francisco Medical Center San Francisco, California | |
| San Francisco Surg Ctr San Francisco, California | |
| San Gabriel Ambulatory Surgery Center San Gabriel, California | |
| San Gabriel Valley Med Ctr San Gabriel, California | |
| San Leandro Surgery Center San Leandro, California | |
| San Mateo Surgery Center San Mateo, California | |
| Sanford Bemidji Med Ctr Bemidji, Minnesota | |
| Sanford Medical Center Fargo, North Dakota | |
| Santa Barbara Outpatient Surgery Center LLC Santa Barbara, California | |
| Santa Clarita Surgery Center Santa Clarita, California | |
| Santa Cruz Valley Regional Hospital Green Valley, Arizona | |
| Santa Fe Surgery Center LLC Lady Lake, Florida | |
| Santa Rosa Surgical Services Santa Rosa, California | |
| Santan Surgery Center Gilbert, Arizona | |
| Sapna Surg Ctr of Potomac Potomac, Maryland | |
| Sarah Bush Lincoln Health Ctr Mattoon, Illinois | |
| Sarasota Surgery Center Sarasota, Florida | |
| Saratoga Surgical Center Corpus Christi, Texas | |
| Sasco Hill Surgery Center Southport, Connecticut | |
| Saunders Medical Center Wahoo, Nebraska | |
| Saxon Surgery Center Thousand Oaks, California | |
| Scottsbluff Surg Ctr Scottsbluff, Nebraska | |
| Scripps Encinitas Surgery Center Encinitas, California | |
| Scripps La Jolla Hospital La Jolla, California | |
| Scripps Mercy Surgery Pavilion San Diego, California | |
| Sea Surgery Center Seal Beach, California | |
| Seacrest Surg Ctr Boynton Beach, Florida | |
| Seashore Surgical Institute Brick, New Jersey | |
| Seaside Surgery Center Naples, Florida | |
| Sebastian River MC Steward Sebastian, Florida | |
| Selby Gen Hosp Marietta, Ohio | |
| Select Physicians Surgery Center Tampa, Florida | |
| Senate Street Surgery Center Indianapolis, Indiana | |
| Sentara RMH Medical Center Harrisonburg, Virginia | |
| Serenity Surgical Munster, Indiana | |
| Seva Pain and Wellness Lewisville, Texas | |
| Sheridan Community Hospital Sheridan, Michigan | |
| Shoreline Surgery Center LLC Long Beach, California | |
| Shrewsbury Surgery Center Shrewsbury, New Jersey | |
| Sidney Reg Med Ctr Sidney, Nebraska | |
| Sierra Medical Center El Paso, Texas | |
| Sierra Surgery Hospital Carson City, Nevada | |
| Signe Spine Surgl Ctr Mt. Pleasant, South Carolina | |
| Silicon Valley ASC Los Gatos, California | |
| Siloam Springs Regional Hospital Siloam Springs, Arkansas | |
| Silver Cross Surgery Center New Lenox, Illinois | |
| Simcare ASC Mount Airy, Maryland | |
| Singing River Gulfport Gulfport, Mississippi | |
| Skyway Surgery Center St. Petersburg, Florida | |
| Smoke Ranch Surgery Center Las Vegas, Nevada | |
| Socal Surg Ctr Hawthorne, California | |
| Somerset Community Hospital Somerset, Pennsylvania | |
| Source Healthcare Santa Monica, California | |
| Source Surgery Center Santa Monica, California | |
| South Austin Surgery Center Austin, Texas | |
| South Bend Clinic ASC South Bend, Indiana | |
| South Bend Specialty Surgery Center Granger, Indiana | |
| South Brooklyn Health Brooklyn, New York | |
| South Central Regional Medical Center Laurel, Mississippi | |
| South Florida Same Day Surg Ctr Pompano Beach, Florida | |
| South Florida Surgery Center South Miami, Florida | |
| South Hills Surgery Center West Mifflin, Pennsylvania | |
| South Kansas City Surgicenter Overland Park, Kansas | |
| South Lake Hosp Clermont, Florida | |
| South Miami Hospital Miami, Florida | |
| South Portland Surgical Center Tualatin, Oregon | |
| South Seminole Medical Center Longwood, Florida | |
| South Shore Surgery Bay Shore, New York | |
| South Tampa Surgery Center, LLC Tampa, Florida | |
| South Valley Surgical Center San Tan Valley, Arizona | |
| Southeast Hospital Cape Girardeau, Missouri | |
| Southeast Michigan Surgical Hospital Warren, Michigan | |
| Southeastern Ambulatory Surgery Center, LLC Lumberton, North Carolina | |
| Southeastern Orthopaedics Surgery Center Douglas, Georgia | |
| Southeastern Spine Institute ASC Mt. Pleasant, South Carolina | |
| Southern Arizona Va Health Care Sys Tucson, Arizona | |
| Southern Grace Pain and Regenerative Medicine Mt. Pleasant, South Carolina | |
| Southern Illinois Healthcare Distribution Center Carbondale, Illinois | |
| Southern Pain and Spine - Jasper Jasper, Georgia | |
| Southern Plains Med Ctr Chickasha, Oklahoma | |
| Southern Surgery Center Hattiesburg, Mississippi | |
| Southern Surgical Center Gray, Louisiana | |
| Southern Tennessee Reg Health Winchester, Tennessee | |
| Southside Hospital Bay Shore, New York | |
| Southside Pain Specialists Birmingham, Alabama | |
| Southside Regional Med Ctr Petersburg, Virginia | |
| Southwest Connecticut Surgery Center Wilton, Connecticut | |
| Southwest Lincoln Surgery Center Lincoln, Nebraska | |
| Southwest Ohio Pain Management Ambulatory Surgery Center Mason, Ohio | |
| Southwest Ohio Surgery Center Middletown, Ohio | |
| Southwest Spine and Pain Ctr Richfield, Utah | |
| Southwest Spine and Pain Ctr Richfield, Utah | |
| Space Coast Surgery Center Merritt Island, Florida | |
| Spanish Hills Surgery Center Camarillo, California | |
| Spartan Health Surgicenter Monongahela, Pennsylvania | |
| Specialists Hospital Shreveport Shreveport, Louisiana | |
| Specialists One Day Surgery Syracuse, New York | |
| Specialists One Day Surgery Syracuse, New York | |
| Speciality Surg Ctr Las Vegas, Nevada | |
| Specialized Outpatient Surg Ctr For Boynton Beach, Florida | |
| Specialty Surg Ctr of Westlake Westlake Village, California | |
| Specialty Surgery Center of CNY Liverpool, New York | |
| Specialty Surgery Center of Middletown Middletown, New Jersey | |
| Specialty Surgical Center of Beverly Hills Beverly Hills, California | |
| Specialty Surgical Center of North Brunswick North Brunswick, New Jersey | |
| Specialty Surgical Ctr Flowood, Mississippi | |
| Specialty Surgl Ctr of Encino Encino, California | |
| Spectrum Health Grand Rapids Grand Rapids, Michigan | |
| Spectrum Pain Clinic Jackson, Tennessee | |
| Spectrum Pain Clinic Jackson, Tennessee | |
| Spicewood Surg Ctr Austin, Texas | |
| Spine & Sports Surgery Center Campbell, California | |
| Spine Center of Excellence Bossier City, Louisiana | |
| Spine Joint and Brain Ctr Springfield, Pennsylvania | |
| Spine Solutions of Green Bay, LLC Green Bay, Wisconsin | |
| Spine Solutions of Sheboygan, LLC Sheboygan, Wisconsin | |
| Spine Solutions of West Bend West Bend, Wisconsin | |
| Spine and Neuro, Health and Wellness Center, LLC Lake Geneva, Wisconsin | |
| Spine and Pain Clinics of North Fairfax, Virginia | |
| Spine and Pain Physicians Surgery Center Smyrna, Tennessee | |
| Spinecare Corpus Christi, Texas | |
| Sports and Spine Pain Management Havre de Grace, Maryland | |
| SportsOrtho Surg Ctr Harlingen, Texas | |
| Spring Creek Surgical Center Providence, Utah | |
| Spring Hospital Spring, Texas | |
| Spring Hospital Spring, Texas | |
| Springfield Regional Medical Center Springfield, Ohio | |
| Ssjc Columbus Columbus, Georgia | |
| Ssm Health St Louis Univ Hosp St Louis, Missouri | |
| Ssm Health St Louis Univ Hosp South St Louis, Missouri | |
| St Anthony Hospital Oklahoma City, Oklahoma | |
| St Anthony Hospital Oklahoma City, Oklahoma | |
| St Charles Hospital Port Jefferson, New York | |
| St Charles Surgical Center Thousand Oaks, California | |
| St Cloud Hosp Saint Cloud, Minnesota | |
| St Elizabeth's Medical Center Boston, Massachusetts | |
| St Francis Med Ctr Cape Girardeau, Missouri | |
| St George Surg Ctr St. George, Utah | |
| St Johns Health System Inc Springfield, Missouri | |
| St Johns Riverside Hospital Yonkers, New York | |
| St Joseph College Station College Station, Texas | |
| St Joseph Hosp Bangor, Maine | |
| St Joseph Med Ctr Kansas City, Missouri | |
| St Joseph Pain Mgmt Ctr Warren, Ohio | |
| St Lukes Health System Boise, Idaho | |
| St Lukes Hosp Kansas City, Missouri | |
| St Lukes Hosp Kansas City, Missouri | |
| St Lukes Hosp Easton Cmps Easton, Pennsylvania | |
| St Lukes Hosp Monroe CMPS Stroudsburg, Pennsylvania | |
| St Lukes Hospital San Francisco, California | |
| St Lukes South Hosp Overland Park, Kansas | |
| St Lukes Surg Ctr Shoal Creek Kansas City, Missouri | |
| St Lukes Surgicenter Lees Summit Lee's Summit, Missouri | |
| St Mary Med Ctr Hobart, Indiana | |
| St Mary Medical Center Apple Valley, California | |
| St Marys Hosp Leonardtown, Maryland | |
| St Marys Med Ctr Huntington, West Virginia | |
| St Marys Regional Med Ctr Enid, Oklahoma | |
| St Nicholas Hosp Sheboygan Surg Ctr Sheboygan, Wisconsin | |
| St Nicholas Hosp Sister of the Sheboygan, Wisconsin | |
| St Peters Ambulatory Surgery Center City of Saint Peters, Missouri | |
| St Vincents Birmingham Birmingham, Alabama | |
| St Vincents One Nineteen Health and Birmingham, Alabama | |
| St. Alexius Medical Center Bismarck, North Dakota | |
| St. Alphonsus Medical Center (Boise) Boise, Idaho | |
| St. Alphonsus Medical Center Nampa Nampa, Idaho | |
| St. Anne Hospital Toledo, Ohio | |
| St. Catherine of Siena Smithtown, New York | |
| St. Elizabeth - Edgewood Edgewood, Kentucky | |
| St. Elizabeth - Florence Florence, Kentucky | |
| St. Francis Hospital Roslyn, New York | |
| St. Francis Mooresville Surgery Center Mooresville, Indiana | |
| St. John Hospital and Medical Center Detroit, Michigan | |
| St. Joseph Health Santa Rosa, California | |
| St. Joseph Health Regional Hospital - Bryan Bryan, Texas | |
| St. Joseph Hospital Denver, Colorado | |
| St. Joseph's Wayne Hospital Wayne, New Jersey | |
| St. Lucie Surgery Center Port Saint Lucie, Florida | |
| St. Luke's Baptist Hospital San Antonio, Texas | |
| St. Luke's Miners Campus Coaldale, Pennsylvania | |
| St. Lukes Anderson County Hospital Garnett, Kansas | |
| St. Mina Interventional Pain Center Warren, Ohio | |
| Stanford Health Care Stanford, California | |
| Stanford Health Care Stanford, California | |
| Stanford Health Care Stanford, California | |
| Stanford Health Care Med Center Palo Alto, California | |
| Stanford Health Care ValleyCare Pleasanton, California | |
| Stanford HealthCare Everyville Emeryville, California | |
| Stanford Hlthcr Tri Valley Livermore, California | |
| Stanislaus Surgical Hospital Modesto, California | |
| Star Med Ctr Plano, Texas | |
| Star Valley Med Ctr Afton, Wyoming | |
| Stellar Surgical Specialties Rancho Mirage, California | |
| Stemmee Surg Ctr Somerset, New Jersey | |
| Sterling Surgical Hospital Slidell, Louisiana | |
| Stockton Surg Ctr Stockton, California | |
| Stonegate Surgery Center Austin, Texas | |
| Stony Brook Eastern Long Island Greenport, New York | |
| Stony Brook Medicine Stony Brook, New York | |
| Stony Brook University Hospital Stony Brook, New York | |
| Stratham Ambulatory Surgery Center Stratham, New Hampshire | |
| Strong Memorial Hospital - University of Rochester Rochester, New York | |
| Sturdy Memorial Hospital Attleboro, Massachusetts | |
| Suffolk Surgery Center Shirley, New York | |
| Sugar Land Surg Ctr Sugar Land, Texas | |
| Summa Pain Care Phoenix, Arizona | |
| Summerport Surgery Center Windermere, Florida | |
| Summit Healthcare Regional Medical Center Show Low, Arizona | |
| Summit Medical Center Edmond, Oklahoma | |
| Summit Spine and Joint Ctr Greenville, South Carolina | |
| Summit Spine and Joint Ctr Greenville, South Carolina | |
| Summit Spine and Joint Ctr Savannah Savannah, Georgia | |
| Summit Spine and Joint Ctrs Dalton, Georgia | |
| Summit Surg Ctr Covington, Louisiana | |
| Summit Surgery Center Hermitage, Tennessee | |
| Summit Surgery Center Hermitage, Tennessee | |
| Summit Surgical Fresno, California | |
| Summit View Surgery Center Littleton, Colorado | |
| Sun City Ambulatory Surgery Center Ruskin, Florida | |
| Sunset Lake Surg Ctr Venice, Florida | |
| Surg Ctr At South Ogden South Ogden, Utah | |
| Surg Ctr of Beverly Hills Beverly Hills, California | |
| Surg Ctr of Columbia County Evans, Georgia | |
| Surg Ctr of Farmington Farmington, Missouri | |
| Surg Ctr of Kalamazoo Portage, Michigan | |
| Surg Ctr of Mid Tennessee Columbia, Tennessee | |
| Surg Ctr of Peoria Peoria, Arizona | |
| Surg Spclsts Asc Fort Walton Beach, Florida | |
| SurgCenter Dunedin Dunedin, Florida | |
| SurgCenter of Glen Burnie Glen Burnie, Maryland | |
| SurgCenter of Northern Baltimore, LLC Hunt Valley, Maryland | |
| SurgCenter of St. Lucie Port Saint Lucie, Florida | |
| Surgcenter NorthEast St. Petersburg, Florida | |
| Surgcenter Northern Phoenix LLC Phoenix, Arizona | |
| Surgcenter Pinellas Largo, Florida | |
| Surgcenter of Fayetteville Fayetteville, Arkansas | |
| Surgcenter of Greater Jacksonville, LLC Jacksonville, Florida | |
| Surgcenter of Palm Beach Gardens Palm Beach Gardens, Florida | |
| Surgcenter of the Potomac Bethesda, Maryland | |
| Surgeons Choice Medical Center Southfield, Michigan | |
| Surgery Center Health Park Grand Blanc, Michigan | |
| Surgery Center at Coral Springs Coral Springs, Florida | |
| Surgery Center at Corporate Way Dayton, Ohio | |
| Surgery Center at Doral Miami, Florida | |
| Surgery Center at Flagstaff Bone and Joint Flagstaff, Arizona | |
| Surgery Center at Pointe West - Lena Rd Bradenton, Florida | |
| Surgery Center at St. Andrews Venice, Florida | |
| Surgery Center of Allentown Allentown, Pennsylvania | |
| Surgery Center of Amarillo Amarillo, Texas | |
| Surgery Center of Aventura Aventura, Florida | |
| Surgery Center of California Chula Vista, California | |
| Surgery Center of Des Moines West West Des Moines, Iowa | |
| Surgery Center of Enid Enid, Oklahoma | |
| Surgery Center of Florida Wesley Chapel, Florida | |
| Surgery Center of Lancaster, L.P. Lancaster, Pennsylvania | |
| Surgery Center of Lynchburg Lynchburg, Virginia | |
| Surgery Center of Mt Dora Mt. Dora, Florida | |
| Surgery Center of Naples Naples, Florida | |
| Surgery Center of New England Springfield, Massachusetts | |
| Surgery Center of North Florida, LLC Gainesville, Florida | |
| Surgery Center of Ocala Ocala, Florida | |
| Surgery Center of Pinehurst Pinehurst, North Carolina | |
| Surgery Center of Reno Reno, Nevada | |
| Surgery Center of San Diego, LLC San Diego, California | |
| Surgery Center of South Bay Torrance, California | |
| Surgery Center of the Pacific Santa Monica, California | |
| Surgery Center of the Rockies Aurora, Colorado | |
| SurgiCare LLC Bloomington, Indiana | |
| SurgiCare of Freehold, LLC Freehold, New Jersey | |
| SurgiCare of Westside New York, New York | |
| SurgiCenter of Baltimore Owings Mills, Maryland | |
| SurgiCore Jersey City Kenilworth, New Jersey | |
| SurgiCore Jersey City Kenilworth, New Jersey | |
| SurgiCore Rockland and Bergen Surgery Center Montvale, New Jersey | |
| Surgical Arts Center Las Vegas, Nevada | |
| Surgical Center of Connecticut Bridgeport, Connecticut | |
| Surgical Center of Mount Dora Mt. Dora, Florida | |
| Surgical Center of New Albany New Albany, Indiana | |
| Surgical Center of South Jersey Mount Laurel, New Jersey | |
| Surgical Centers of Arizona Scottsdale, Arizona | |
| Surgical Hospital of Oklahoma Oklahoma City, Oklahoma | |
| Surgical Institute of Beverly Hills Beverly Hills, California | |
| Surgical Institute of Monroe Monroe, Michigan | |
| Surgical Institute of Reading Wyomissing, Pennsylvania | |
| Surgical Pain Center of the Adirondacks Plattsburgh, New York | |
| Surgical Park Center Miami, Florida | |
| Surgical Specialists at Princeton Princeton, New Jersey | |
| Surgical Specialty Center of Mid-Atlantic, LLC Bethesda, Maryland | |
| Surgical Specialty Center of Westchester Harrison, New York | |
| Surgical Studios Mullica Hill, New Jersey | |
| Surgicare of Jackson Jackson, Mississippi | |
| Surgicare of Manhattan, LLC New York, New York | |
| Surgicare of Miramar Miramar, Florida | |
| Surgicenter of Johnson County Overland Park, Kansas | |
| Surgicore Midtown/Manhattan New York, New York | |
| Surgicore North Queens Bayside, New York | |
| Surgicore North Queens Surgical Center Bayside, New York | |
| Surgicore of Saddle Brook Saddle Brook, New Jersey | |
| Susquehanna Surgery Center Bloomsburg, Pennsylvania | |
| Susquehanna Valley Pain Management Harrisburg, Pennsylvania | |
| Sutter Auburn Surgery Center Auburn, California | |
| Sutter Elk Grove Surg Ctr Elk Grove, California | |
| Sutter Lakeside Hospital Lakeport, California | |
| Sutter Sierra Surgery Center Roseville, California | |
| Sutter Tracy Community Hospital Tracy, California | |
| Swedish Amb Surg Ctr Chicago, Illinois | |
| Swedish American Med Ctr Belvidere Belvidere, Illinois | |
| Swedish Covenant Hosp Chicago, Illinois | |
| Swedishamerican Health System Rockford, Illinois | |
| Sycamore Hospital Miamisburg, Ohio | |
| Synergy Spine & Orthopedic Surgery Center, LLC Warren, Michigan | |
| Synergy Spine and Pain Ctr Glenn Dale, Maryland | |
| Synergy Surg Ctr Englewood, Colorado | |
| Synergy Surgical Center, LLC Westlake Village, California | |
| Syringa Outpatient Surgery Center Meridian, Idaho | |
| TOPS Specialty Hospital Houston, Texas | |
| Tampa Gen Hosp Tampa, Florida | |
| Tanner Medical Center Carrollton, Georgia | |
| Taylor Station Surgical Center Columbus, Ohio | |
| TeamMD Surgery Center Woodland Park, New Jersey | |
| Teaneck Surgery Center Teaneck, New Jersey | |
| Temple University Hospital Philadelphia, Pennsylvania | |
| Terre Haute Surgical Center Terre Haute, Indiana | |
| Texas Health Surg Ctr Rockwall Rockwall, Texas | |
| Texas Ortho Ctr of Excellence Corpus Christi, Texas | |
| Texas Pain Physicians Waxahachie, Texas | |
| Texas Precision Surgery Center Corpus Christi, Texas | |
| Texas Spine & Joint Hospital Tyler, Texas | |
| Thayer County Health Services Hebron, Nebraska | |
| The Advanced Center for Surgery Vero Beach, Florida | |
| The Center For Outpatient Medicine Bloomington, Illinois | |
| The Center for Minimally Invasive Surgery Munster, Indiana | |
| The Charlotte Hungerford Hospital Torrington, Connecticut | |
| The Christ Hospital Cincinnati, Ohio | |
| The Ctr For Outpatient Surg Tinton Falls, New Jersey | |
| The Gables Surgical Center Coral Gables, Florida | |
| The Heights Hospital Houston, Texas | |
| The Imaging and Spine Center - UNC Hospitals Chapel Hill, North Carolina | |
| The Medical Center of Southeast Texas-Beaumont Campus Beaumont, Texas | |
| The Ohio Pain Clinic Centerville, Florida | |
| The Orthopedic Surgery Center Youngstown, Ohio | |
| The Outpatient Center of Delray Delray Beach, Florida | |
| The Pain Management Center of Meridian Meridian, Mississippi | |
| The Pain Treatment Center - URMC Rochester, New York | |
| The Pain Treatment Center, Inc. Lexington, Kentucky | |
| The Saint Francis Hospital Center for Pain Relief Charleston, West Virginia | |
| The Spine Care Manassas, Virginia | |
| The Surgery Center Victoria, Texas | |
| The Surgery Center Victoria, Texas | |
| The Surgery Center LLC Franklin, Wisconsin | |
| The Surgery Center at Edgewater Fort Mill, South Carolina | |
| The Surgery Center at Fort Washington Fort Washington, Pennsylvania | |
| The Surgery Center at Lone Tree Lone Tree, Colorado | |
| The Surgery Center at Orthopedic Associates LL Poughkeepsie, New York | |
| The Surgery Center at TGH Brandon Healthplex Tampa, Florida | |
| The Surgery Center at Westpark Zeeland, Michigan | |
| The Surgery Center of Chester County Exton, Pennsylvania | |
| The Surgery Center of Cleveland Cleveland, Tennessee | |
| The Surgery Center of Columbia Columbia, Missouri | |
| The Surgery Center of Ft. Lauderdale Lauderdale Lakes, Florida | |
| The Surgical Center at Columbia Orthopaedic Group Columbia, Missouri | |
| The Surgical Center of the Treasure Coast Port Saint Lucie, Florida | |
| The Surgical Pavilion Little Rock, Arkansas | |
| The Univ of Alabama At Birmingham Birmingham, Alabama | |
| The Univ of Mississippi Med Ctr Jackson, Mississippi | |
| The University of Toledo Medical Center Toledo, Ohio | |
| The Vancouver Clinic Inc. Vancouver, Washington | |
| ThedaCare Inc. - Neenah Neenah, Wisconsin | |
| ThedaCare Medical Center - Orthopedic Spine & Pain Appleton, Wisconsin | |
| ThedaCare Regional Medical Center-Appleton Appleton, Wisconsin | |
| Thibodaux Regional Health System Thibodaux, Louisiana | |
| Thomas Jefferson Univ Hosp Philadelphia, Pennsylvania | |
| Thomas Johnson Surgery Center Frederick, Maryland | |
| Thomas Mem Hosp South Charleston, West Virginia | |
| Thousand Oaks Surgery Center Thousand Oaks, California | |
| Three Gables Surgery Center Proctorville, Ohio | |
| Three Rivers Health Three Rivers, Michigan | |
| Tier 1 Asc Cookeville, Tennessee | |
| Tilden Asc Hamburg, Pennsylvania | |
| Timonium Surgery Center Timonium, Maryland | |
| Tinley Woods Surgery Center Tinley Park, Illinois | |
| Titus County Mem Hosp Mount Pleasant, Texas | |
| Titusville Surgery Center Titusville, Florida | |
| Toledo Clinic Outpatient Surgery Toledo, Ohio | |
| Toms River Surgery Center Toms River, New Jersey | |
| Total Body Pain Institute Grand Island, Nebraska | |
| Total Pain Care Meridian, Mississippi | |
| Touchton Surgery Center Jacksonville, Florida | |
| Towne Centre Surgery Center Saginaw, Michigan | |
| Townsen Mem Surg Ctr Katy Katy, Texas | |
| Townsen Memorial ASC Medical Center Houston, Texas | |
| Townsen Memorial Hospital Humble, Texas | |
| Townsen Memorial Surgery Center Spring Spring, Texas | |
| Townsen Memorial Surgery Center-Kingwood Kingwood, Texas | |
| Townsend Mem Hosp West Houston, Texas | |
| Trails Edge Surgery center LLC Bonita Springs, Florida | |
| Trevose Specialty Care Surgical Center Trevose, Pennsylvania | |
| Tri-State Memorial Hospital Clarkston, Washington | |
| Tri-State Surgical Center Martinsburg, West Virginia | |
| TriHealth Evendale Hospital Cincinnati, Ohio | |
| Trihealth Surg Ctr West Cincinnati, Ohio | |
| Trinitas Hospital Elizabeth, New Jersey | |
| Trinity Bettendorf Hosp Bettendorf, Iowa | |
| Trinity Health System Trinity West Steubenville, Ohio | |
| Trinity Mother Frances Hospital Tyler, Texas | |
| Trinity Surgery Center San Jose, California | |
| Trinity Surgical and Pain Management dba Performance Surgical Associates Bridgewater, New Jersey | |
| Truman Medical Center Kansas City, Missouri | |
| Trumbull Regional Medical Center Warren, Ohio | |
| Tucson Med Ctr Tucson, Arizona | |
| Tucson Med Ctr Rincon Tucson, Arizona | |
| Tucson Surgery Center Tucson, Arizona | |
| Tufts Med Ctr Boston, Massachusetts | |
| Tulsa Amb Procedure Tulsa, Oklahoma | |
| Tulsa Procedure Suites Tulsa, Oklahoma | |
| Turkey Creek Medical Center (Tennova) Knoxville, Tennessee | |
| Turks Head Surg Ctr West Chester, Pennsylvania | |
| Tuscaloosa Surgery Center Tuscaloosa, Alabama | |
| Twin Cities Pain Clinic and Surgery Center Edina, Minnesota | |
| Twin Cities Pain Clinic- Burnsville Burnsville, Minnesota | |
| Twin Cities Surg Ctr Maplewood Maplewood, Minnesota | |
| Twin Cities Surgery Center Festus, Missouri | |
| Two Rivers Surgical Center Eugene, Oregon | |
| Two Twelve Surgery Center Chaska, Minnesota | |
| Tyler Tx Asc Tyler, Texas | |
| U of M Sparrow Eaton Hospital Charlotte, Michigan | |
| U.T MD Anderson Cancer Center Houston, Texas | |
| UC Davis Medical Cetner-Lawrence Ellison Ambulatory Care Building Sacramento, California | |
| UCI Medical Center- Central Distribution Warehouse - Dyer Santa Ana, California | |
| UCLA Med Ctr Los Angeles, California | |
| UCLA Medical Center Santa Monica Santa Monica, California | |
| UCLA-Thousand Oaks Thousand Oaks, California | |
| UCSD Health MOP San Diego, California | |
| UCSD Medical Center San Diego, California | |
| UCSF Medical Center San Francisco, California | |
| UF Health Shands Hospital Gainesville, Florida | |
| UF Health Shands Hospital Gainesville, Florida | |
| UF Health Shands Hospital Gainesville, Florida | |
| UH Portage Medical Center Ravenna, Ohio | |
| UH Samaritan Medical Center Ashland, Ohio | |
| UHealth Miami Med Ctr North Miami, Florida | |
| UIC Medical Center- University of Illinois Medical Center Chicago, Illinois | |
| UK Interventional Pain Associates Lexington, Kentucky | |
| UNC Hospitals - Hillsborough Campus Hillsborough, North Carolina | |
| UNC Hospitals - Shared Services Durham, North Carolina | |
| UNC Lenoir Health Care Kinston, North Carolina | |
| UTMB Health League City Campus Hospital League City, Texas | |
| Uci Health Irvine Irvine, California | |
| Ucsd Med Ctr Hillcrest San Diego, California | |
| Uf Health St Johns Saint Augustine, Florida | |
| Uintah Basin Medical Center Roosevelt, Utah | |
| Ukiah Valley Med Ctr Ukiah, California | |
| Umc El Paso Surg Ctr El Paso, Texas | |
| Unicare Surgery Center Anaheim, California | |
| Union County Surgery Center Union, New Jersey | |
| Union Hospital Terre Haute, Indiana | |
| United Medical Park ASC, LLC Waterloo, Iowa | |
| United Memorial Medical Center Sugar Land, Texas | |
| United Memorial Medical Center Sugar Land, Texas | |
| United Memorial Medical Center - North Hospital Houston, Texas | |
| United Surgery Center-Temecula Temecula, California | |
| UnityPoint Health Waterloo Waterloo, Iowa | |
| UnityPoint Methodist Comprehensive Pain Management Center Peoria, Illinois | |
| Univ Health Surg Ctr Mac San Antonio, Texas | |
| Univ Hosp San Antonio, Texas | |
| Univ Hosp San Antonio, Texas | |
| Univ Hosp Westlake Westlake, Ohio | |
| Univ Hosps Conneaut Medic Conneaut, Ohio | |
| Univ Hosps Geneva Med Ctr Geneva, Ohio | |
| Univ Med Ctr of El Paso El Paso, Texas | |
| Univ Ortho Assocs Somerset, New Jersey | |
| Univ of California Davis Sacramento, California | |
| Univ of California Irvine Med Ctr Orange, California | |
| Univ of Chicago Crown Point Crown Point, Indiana | |
| Univ of Florida Health Jacksonville Jacksonville, Florida | |
| Univ of Maryland Orthopaedics Columbia, Maryland | |
| Univ of Miami Sylvester Miami, Florida | |
| Univ of Michigan Univ Hosp Ann Arbor, Michigan | |
| Univ of Mississippi Med Ctr Jackson, Mississippi | |
| Univ of Texas Southwestern Med Ctr Dallas, Texas | |
| Univ of Vermont Med Williston, Vermont | |
| University Center for Ambulatory Surgery Somerset, New Jersey | |
| University Hospital San Antonio, Texas | |
| University Hospitals Ahuja Medical Center Beachwood, Ohio | |
| University Hospitals Cleveland Medical Center Cleveland, Ohio | |
| University Hospitals Health System St John Medical Center Westlake, Ohio | |
| University Hospitals- Suburban South Euclid, Ohio | |
| University Pain Associates Houston, Texas | |
| University Surgery Center Murrieta, California | |
| University of Arkansas for Medical Sciences Little Rock, Arkansas | |
| University of Chicago Medical Center Chicago, Illinois | |
| University of Kansas Health System St. Francis Campus Topeka, Kansas | |
| University of Kansas Medical Center Kansas City, Kansas | |
| University of Kentucky Lexington, Kentucky | |
| University of Louisville Hospital Louisville, Kentucky | |
| University of New Mexico Hospital Albuquerque, New Mexico | |
| University of Texas Medical Branch - Clear Lake Webster, Texas | |
| University of Virginia Health System Charlottesville, Virginia | |
| University of Virginia Health System Charlottesville, Virginia | |
| Upland Hills Health Dodgeville, Wisconsin | |
| Upper Bay Surgery Center Elkton, Maryland | |
| Upper Peninsula Surgery Center Marquette, Michigan | |
| Upper Valley Dialysis ASC Mission, Texas | |
| Upstate Univ Hosp Syracuse, New York | |
| Ut Health Marc Asc San Antonio, Texas | |
| Utsw Zale Lipshy Dallas, Texas | |
| Uva Med Ctr 29 Warehouse Charlottesville, Virginia | |
| VA Hospital - Gainsville Gainesville, Florida | |
| VA Medical Center Albuquerque, New Mexico | |
| VA Medical Center - Cooper Dr Div Lexington, Kentucky | |
| VA Medical Center - Little Rock Little Rock, Arkansas | |
| VA Medical Center - Loma Linda Loma Linda, California | |
| VA Medical Center - San Diego San Diego, California | |
| VA Medical Center Augusta Augusta, Georgia | |
| VA Medical Center Cincinnati Cincinnati, Ohio | |
| VA Medical Center Cleveland Cleveland, Ohio | |
| VA Medical Center Indianapolis Indianapolis, Indiana | |
| VA Medical Center Kansas City Kansas City, Missouri | |
| VA Medical Center Pecos MSPV Las Vegas, Nevada | |
| VA Medical Center Richmond Richmond, Virginia | |
| VA New York Harbor (Margaret Cochran Corbin Campus) New York, New York | |
| VCU Health Ambulatory Surgery Center Henrico, Virginia | |
| VCU Health System Authority Richmond, Virginia | |
| VIP Surgical Center Conroe, Texas | |
| Valley Ambulatory Surgery Center McAllen, Texas | |
| Valley Ambulatory Surgery Center McAllen, Texas | |
| Valley Health Surgery Center Winchester, Virginia | |
| Valley Pain Center Huntingdon Valley, Pennsylvania | |
| Valley Surgical Ctr Bethlehem, Pennsylvania | |
| Vanguard Medical Group Michigan City, Indiana | |
| Vantage Surgery Center Medford, New Jersey | |
| Venice Regional Bayfront Health Venice, Florida | |
| Ventana Surgical Center Tarzana, California | |
| Vero Beach Surgery Center Vero Beach, Florida | |
| Vicksburg Spine Ctr Vicksburg, Mississippi | |
| Vidant Chowan Hosp Edenton, North Carolina | |
| Vidant Medical Center Greenville, North Carolina | |
| Vidant Roanoke Chowan Hospital- Pain Management Ahoskie, North Carolina | |
| Vidant Roanoke-Chowan Hospital Greenville Greenville, North Carolina | |
| Viewmont Surgery Center Hickory, North Carolina | |
| Village Pointe Health Center Omaha, Nebraska | |
| Vineyard Surg Ctr Orem, Utah | |
| Virginia Commonwealth Univ Henrico, Virginia | |
| Virginia Interventional Pain and Roanoke, Virginia | |
| Virginia Spine Instu Reston, Virginia | |
| Virtuous Health Centers III Scottsdale, Arizona | |
| Vista Medical Center East Waukegan, Illinois | |
| WHS East Campus Decatur, Texas | |
| WHS Pain Management Center at Southlake Southlake, Texas | |
| WI Surgery Center Milwaukee, Wisconsin | |
| WV University Hospitals Morgantown, West Virginia | |
| Wake Spine and Specialty Surg Ctr Raleigh, North Carolina | |
| WakeMed North Hospital Raleigh, North Carolina | |
| WakeMed Raleigh Campus Raleigh, North Carolina | |
| Wakemed Cary Surg Ctr Cary, North Carolina | |
| Wakemed North Family Health and Raleigh, North Carolina | |
| Walter Reed Medical Center Bethesda, Maryland | |
| Warren General Hospital Warren, Pennsylvania | |
| Washington Dc Va Med Ctr Washington D.C., District of Columbia | |
| Water Leaf Surgery Center, LTD Austin, Texas | |
| Watts Plastic Surgical Center Vineland, New Jersey | |
| Wauwatosa Surgery Center Wauwatosa, Wisconsin | |
| Waverly Health Center Waverly, Iowa | |
| Waverly Surgery Center Albany, Oregon | |
| Weiss Memorial Hospital Chicago, Illinois | |
| WellStar North Fulton Hospital Roswell, Georgia | |
| Wellington Endoscopy Center Wellington, Florida | |
| Wellspring Pain Solutions Columbus, Indiana | |
| Wellward Regenerative Medicine Lexington, Kentucky | |
| Wentworth-Douglass Hospital Dover, New Hampshire | |
| West Bend Surg Ctr Menomonee Falls, Wisconsin | |
| West Central Surgical Center Toledo, Ohio | |
| West Central Surgical Center Bayside Oregon, Ohio | |
| West Chester Hosp West Chester, Ohio | |
| West Chester Surgical Suites West Chester, Ohio | |
| West Florida Surgical Suites Tampa, Florida | |
| West Georgia Surg Ctr Carrollton, Georgia | |
| West Hartford Surgery Center West Hartford, Connecticut | |
| West Jefferson Med Ctr Marrero, Louisiana | |
| West Lakes Surgery Center Clive, Iowa | |
| West Marion Community Hospital Ocala, Florida | |
| West Michigan Surgery Center Big Rapids, Michigan | |
| West Michigan Surgery Center Big Rapids, Michigan | |
| West Michigan Surgical Center Zeeland, Michigan | |
| West Morris Surgery Center Succasunna, New Jersey | |
| West Park Ambulatory Surgery Center Pinellas Park, Florida | |
| West Park Surgery Center Cape Girardeau, Missouri | |
| West Penn Hosp Pittsburgh, Pennsylvania | |
| West Plains Surgery Center West Plains, Missouri | |
| West Surgical ASC Camillus, New York | |
| Westchase Surgery Center Tampa, Florida | |
| Western Connecticut Orthopedic Surgical Center Danbury, Connecticut | |
| Western Missouri Med Ctr Warrensburg, Missouri | |
| Western PA Surg Ctr Beaver County Aliquippa, Pennsylvania | |
| Western PA Surgery Center Wexford, Pennsylvania | |
| Western Reserve Hospital Cuyahoga Falls, Ohio | |
| Westown Ambulatory Center West Des Moines, Iowa | |
| Wetzel County Hospital New Martinsville, West Virginia | |
| Wheeling Hospital Wheeling, West Virginia | |
| White Hall Ambulatory Surgery Center White Hall, Arkansas | |
| White River Med Ctr Batesville, Arkansas | |
| Wilkes Barre General Hospital Wilkes-Barre, Pennsylvania | |
| William Bee Ririe Hospital Ely, Nevada | |
| William Jennings Bryan Dorn Va Med Columbia, South Carolina | |
| Willis-Knighton Medical Center Shreveport, Louisiana | |
| Wilmington Health ASC Wilmington, North Carolina | |
| Wilmington SurgCare Wilmington, North Carolina | |
| Windsor Mill Surg Ctr Windsor Mill, Maryland | |
| Winter Garden Surg Ctr Winter Garden, Florida | |
| Winter Haven Ambulatory Surgical Center Winter Haven, Florida | |
| Wisconsin Spine and Pain Surg Ctr Sheboygan, Wisconsin | |
| Wisconsin Spine and Pain West Bend West Bend, Wisconsin | |
| Witham Health Services Lebanon, Indiana | |
| Woodland Heights Med Center Lufkin, Texas | |
| Wright Patterson Hospital Wright-Patterson Air Force Base, Ohio | |
| Wyatt Surg Ctr Tucson, Arizona | |
| Wyomissing Surgical Services Wyomissing, Pennsylvania | |
| Yale New Haven Health-Greenwich Hospital Greenwich, Connecticut | |
| Yale New Haven Hosp New Haven, Connecticut | |
| Yale New Haven Hosp St Raphael Cmps New Haven, Connecticut | |
| York Hosp York Village, Maine | |
| Youngstown Orthopedic Associates Youngstown, Ohio | |
| Zion Eye Institute St. George, Utah |
Testing the Addition of a New Anti-cancer Drug, M3814 (Peposertib), to the Usual Radiotherapy in Patients With Locally Advanced Pancreatic Cancer
ctrrecruit@vcu.edu
NCT04172532
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Inclusion Criteria:
* Patients must have pathologically confirmed pancreatic adenocarcinoma. Patients with alternative or mixed histologies (i.e., squamous, neuroendocrine, acinar, colloid) are not eligible
* Received 4-6 months of induction chemotherapy with fluorouracil, irinotecan, leucovorin and oxaliplatin (FOLFIRINOX), fluorouracil, liposomal irinotecan, leucovorin, oxaliplatin (NALIRIFOX), or gemcitabine/Abraxane, as per standard of care
* Patients must have locally advanced pancreatic cancer according to National Comprehensive Cancer Network (NCCN) Guidelines (version 1.2020) on pancreas protocol CT scan performed within 21 days of registration. Locally advanced disease is defined as any of the following:
* For head or uncinate process tumors:
* Solid tumor contact with superior mesenteric artery \> 180 degrees
* Solid tumor contact with the celiac axis \> 180 degrees
* Solid tumor contact with the common or proper hepatic arteries \> 180 degrees or
* For pancreatic body or tail tumors:
* Solid tumor contact of \> 180 degrees with the superior mesenteric artery or celiac axis
* Solid tumor contact with the celiac axis and aortic involvement or
* Unreconstructible superior mesenteric vein or portal vein due to tumor involvement or occlusion (can be due to tumor or bland thrombus)
* The determination of locally advanced pancreatic cancer and plan for non-operative treatment on this clinical trial must be confirmed through local multi-disciplinary review
* Measurable disease per response evaluation criteria in solid tumors (RECIST) version (v)1.1
* Age \>= 18 years. Because no dosing or adverse event data are currently available on the use of M3814 (peposertib) in combination with hypofractionated radiation in patients \< 18 years of age, children are excluded from this study, but will be eligible for future pediatric trials
* Eastern Cooperative Oncology Group (ECOG) performance status =\< 2 (Karnofsky \>= 60%)
* Leukocytes \>= 4,000/mcL
* Absolute neutrophil count \>= 1.5 x 10\^9/L.
* Hemoglobin \>= 9 g/dL
* Platelets \>= 100 x 10\^9/L
* Total bilirubin =\< 2.0 x institutional upper limit of normal (ULN)
* Aspartate aminotransferase (AST) (serum glutamic oxaloacetic transaminase \[SGOT\])/alanine aminotransferase (ALT) (serum glutamic pyruvic transaminase \[SGPT\]) =\< 3 x institutional ULN
* Creatinine =\< 1.5 x institutional ULN
* Glomerular filtration rate (GFR) \>= 51 mL/min/1.73 m\^2
* Human immunodeficiency virus (HIV)-infected patients on effective anti-retroviral therapy with undetectable viral load within 6 months are eligible for this trial
* For patients with evidence of chronic hepatitis B virus (HBV) infection, the HBV viral load must be undetectable on suppressive therapy, if indicated
* Patients with a history of hepatitis C virus (HCV) infection must have been treated and cured. For patients with HCV infection who are currently on treatment, they are eligible if they have an undetectable HCV viral load
* Female patients of childbearing potential must have a negative urine or serum pregnancy test within 72 hours prior to receiving the first dose of study medication. If the urine test is positive or cannot be confirmed as negative, a serum pregnancy test will be required. Female patients of childbearing potential and male patients must be willing to use an adequate method of contraception for the course of the study through 12 weeks after the last dose of study medication.
* Note: Abstinence is acceptable if this is the usual lifestyle and preferred contraception for the patient.
* Patients with known history or current symptoms of cardiac disease, or history of treatment with cardiotoxic agents, should have a clinical risk assessment of cardiac function. To be eligible for this trial, patients should be American Heart Association Stage B (people without current or previous symptoms of heart failure but with either structural heart disease, increased filling pressures in the heart or other risk factors) or better and New York Heart Association Functional Classification II (slight limitation of physical activity, comfortable at rest, ordinary physical activity results in fatigue, palpitation, shortness of breath or chest pain), or better
* Ability to understand and the willingness to sign a written informed consent document. Participants with impaired decision-making capacity (IDMC) who have a legally authorized representative (LAR) and/or family member available will also be eligible
Exclusion Criteria:
* Patients who have completed induction chemotherapy less than 2 weeks or more than 8 weeks prior to study enrollment
* Patients who have not recovered from adverse events due to prior anti-cancer therapy (i.e., have residual toxicities \> grade 1) with the exception of alopecia and neuropathy grade =\< 2
* Patients who are receiving any other investigational agents
* History of allergic reactions attributed to compounds of similar chemical or biologic composition to M3814 (peposertib)
* Evidence of distant metastatic disease
* More than 1 line of chemotherapy for the treatment of localized pancreatic cancer, unless the change in treatment was made only for toxicity
* Prior abdominal radiation
* Active inflammatory bowel disease or connective tissue disease
* Inability to swallow oral medications or gastrointestinal disease limiting absorption of oral agents
* History of anaphylactic reaction to iodinated intravenous (IV) contrast required for radiation simulation. Patients with mild reactions may be enrolled, but must receive premedications for contrast allergy prior to imaging
* Patients who cannot discontinue concomitant medications or herbal supplements that are strong inhibitors or strong inducers of cytochrome P450 (CYP) isoenzymes CYP3A4/5, CYP2C9, and CYP2C19. Concomitant use of substrates with a narrow therapeutic index that are metabolized by CYP1A2, CYP2B6, CYP2C8, and CYP3A4/5 are also excluded.
* Use caution with other substrates of CYP3A4/5, CYP1A2, CYP2B6, CYP2C8 and substrates of P-gp, BCRP, OCT1, OAT3, OATP1B1, OATP1B3, MATE1, and MATE-2K with a narrow therapeutic index. Close monitoring is advised.
Because the lists of these agents are constantly changing, it is important to regularly consult a frequently-updated medical reference. As part of the enrollment/informed consent procedures, the patient will be counseled on the risk of interactions with other agents, and what to do if new medications need to be prescribed or if the patient is considering a new over-the-counter medicine or herbal product. (Patient Drug Interactions Handout and Wallet Card) should be provided to patients
* Patients who cannot discontinue concomitant proton-pump inhibitors (PPIs). Patients may confer with the study doctor to determine if such medications can be discontinued. These must be discontinued \>= 5 days prior to study treatment. Patients do not need to discontinue calcium carbonate. H2 blockers and antacids are allowed.
* Patients who have received a live attenuated vaccine within 30 days of dosing with M3814 (peposertib)
* Patients with uncontrolled intercurrent illness
* Patients with psychiatric illness/social situations that would limit compliance with study requirements
* Pregnant women are excluded from this study because M3814 (peposertib) is a DNA-protein kinase (PK) inhibitor with the potential for teratogenic or abortifacient effects. Because there is an unknown but potential risk for adverse events in nursing infants secondary to treatment of the mother with M3814 (peposertib), breastfeeding should be discontinued if the mother is treated with M3814 (peposertib)
* Patients with a prior or concurrent malignancy whose natural history or treatment has the potential to interfere with the safety or efficacy assessment of this investigational regimen PROCEDURE: Biopsy Procedure, PROCEDURE: Biospecimen Collection, PROCEDURE: Computed Tomography, RADIATION: Hypofractionated Radiation Therapy, PROCEDURE: Magnetic Resonance Imaging, DRUG: Peposertib, OTHER: Placebo Administration
Locally Advanced Pancreatic Adenocarcinoma, Stage III Pancreatic Cancer AJCC v8
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Show 44 locations
Study Locations
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| Location | Contacts |
|---|---|
| City of Hope Comprehensive Cancer Center Duarte, California | Site Public Contact - (becomingapatient@coh.org) |
| City of Hope at Irvine Lennar Irvine, California | |
| Cooperman Barnabas Medical Center Livingston, New Jersey | |
| Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center Lebanon, New Hampshire | |
| HaysMed Hays, Kansas | |
| Huntsman Cancer Institute/University of Utah Salt Lake City, Utah | |
| Laura and Isaac Perlmutter Cancer Center at NYU Langone New York, New York | |
| Lawrence Memorial Hospital Lawrence, Kansas | Site Public Contact - (Stephanie.Norris@LMH.ORG) |
| Mercy Hospital Pittsburg Pittsburg, Kansas | |
| Monmouth Medical Center Long Branch, New Jersey | Site Public Contact - (mary.danish@rwjbh.org) |
| Montefiore Medical Center - Moses Campus The Bronx, New York | |
| Montefiore Medical Center-Einstein Campus The Bronx, New York | |
| Mount Sinai Hospital New York, New York | Site Public Contact - (CCTO@mssm.edu) |
| NYP/Weill Cornell Medical Center New York, New York | |
| Northwestern University Chicago, Illinois | |
| Roswell Park Cancer Institute Buffalo, New York | |
| Rutgers Cancer Institute of New Jersey New Brunswick, New Jersey | |
| Salina Regional Health Center Salina, Kansas | Site Public Contact - (mleepers@srhc.com) |
| Sibley Memorial Hospital Washington D.C., District of Columbia | Site Public Contact - (jquiver1@jhmi.edu) |
| The University of Kansas Cancer Center - Olathe Olathe, Kansas | Site Public Contact - (OlatheCCResearch@kumc.edu) |
| UC Irvine Health/Chao Family Comprehensive Cancer Center Orange, California | Site Public Contact - (ucstudy@uci.edu) |
| UCHealth University of Colorado Hospital Aurora, Colorado | |
| UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care Irvine, California | Site Public Contact - (ucstudy@uci.edu) |
| UPMC Hillman Cancer Center Pittsburgh, Pennsylvania | |
| University Health Truman Medical Center Kansas City, Missouri | |
| University of California Davis Comprehensive Cancer Center Sacramento, California | |
| University of Kansas Cancer Center Kansas City, Kansas | Site Public Contact - (KUCC_Navigation@kumc.edu) |
| University of Kansas Cancer Center - Lee's Summit Lee's Summit, Missouri | Site Public Contact - (KUCC_Navigation@kumc.edu) |
| University of Kansas Cancer Center - North Kansas City, Missouri | Site Public Contact - (KUCC_Navigation@kumc.edu) |
| University of Kansas Cancer Center at North Kansas City Hospital North Kansas City, Missouri | |
| University of Kansas Cancer Center-Overland Park Overland Park, Kansas | Site Public Contact - (KUCC_Navigation@kumc.edu) |
| University of Kansas Clinical Research Center Fairway, Kansas | Site Public Contact - (KUCC_Navigation@kumc.edu) |
| University of Kansas Health System Saint Francis Campus Topeka, Kansas | |
| University of Kansas Hospital-Westwood Cancer Center Westwood, Kansas | Site Public Contact - (KUCC_Navigation@kumc.edu) |
| University of Kentucky/Markey Cancer Center Lexington, Kentucky | |
| University of Wisconsin Carbone Cancer Center - Eastpark Medical Center Madison, Wisconsin | Site Public Contact - (clinicaltrials@cancer.wisc.edu) |
| University of Wisconsin Carbone Cancer Center - University Hospital Madison, Wisconsin | Site Public Contact - (clinicaltrials@cancer.wisc.edu) |
| VCU Massey Comprehensive Cancer Center Richmond, Virginia | |
| Vanderbilt University/Ingram Cancer Center Nashville, Tennessee | |
| Wake Forest Baptist Health - Wilkes Medical Center Wilkesboro, North Carolina | |
| Wake Forest University Health Sciences Winston-Salem, North Carolina | |
| Wake Forest University at Clemmons Clemmons, North Carolina | |
| Wayne State University/Karmanos Cancer Institute Detroit, Michigan | |
| Weisberg Cancer Treatment Center Farmington Hills, Michigan |
4D-710 in Adult Patients With Cystic Fibrosis (CF)
4DMT Patient Advocacy - clinicaltrials@4DMT.com
NCT05248230
Show full eligibility criteria
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Key Inclusion Criteria (Primary Study):
• 18 years and older
• Confirmed diagnosis of cystic fibrosis (CF) and CF lung disease including:
• Sweat chloride ≥ 60 mmol/L
• Mutation Status * Bi-allelic mutations in the CFTR gene, or * Single mutation in the CFTR gene and clinical manifestations of CF lung disease
• Ineligible for CFTR modulator therapy, or previously received modulator therapy but discontinued due to adverse effects.
• Forced expiratory volume in 1 second (FEV1) ≥ 50% and ≤ 90% of predicted (per Global Lung Function Initiative) at Screening
• Resting oxygen saturation ≥ 92% on room air at Screening Key Inclusion Criteria (Sub-Study):
• 18 years and older
• Confirmed diagnosis of cystic fibrosis (CF) and CF lung disease including:
• Sweat chloride ≥ 60 mmol/L
• Mutation Status * Bi-allelic mutations in the CFTR gene, or * Single mutation in the CFTR gene and clinical manifestations of CF lung disease
• Currently on a stable dose of CFTR modulator therapy for a minimum of 60 days prior to Screening and agree to maintain current regimen through the 24-month Observation Period
• FEV1 ≥ 40% and \< 70% predicted (per Global Lung Function Initiative) at Screening, AND/OR experienced at least 2 pulmonary exacerbations in the last year requiring intravenous antibiotics Key Exclusion Criteria (Primary and Sub Study):
• Any prior gene therapy for any indication (Exception: mRNA-based or antisense oligonucleotide therapies are not exclusionary)
• Active Mycobacterium abscessus infection requiring ongoing treatment at Screening
• Active allergic bronchopulmonary aspergillosis requiring management with systemic corticosteroids or antifungal therapy
• Smoking (e.g. cigarettes, cigars, cannabis) or use of a vaping product during the 2 months prior to screening; must agree to not smoke or use vaping products during Screening and initial 24-month observation period.
• Contraindication to systemic corticosteroid therapy
• Requires chronic use of systemic corticosteroids or immunosuppressants to treat another condition
• If no known diagnosis of cystic fibrosis related diabetes (CFRD), Type I, or Type II diabetes: Hemoglobin A1C ≥ 6.5% at Screening
• If known diagnosis of CFRD, Type I or Type II diabetes: Hemoglobin A1C \> 7.5% at Screening
• Recent history of symptomatic hyperglycemia or unstable blood glucose levels as per Investigator's assessment
• Other conditions that, in the Investigator's opinion, may interfere with management of corticosteroid-related hyperglycemia
• Body Mass Index (BMI) \< 16
• Laboratory abnormalities at screening: * ALT, AST or GGT ≥ 3 × the upper limit of normal (ULN) * Total bilirubin ≥ 2 × ULN * Hemoglobin \< 10 g/dL
• Requirement for continuous or night-time oxygen supplementation
• Known CF liver disease with evidence of multilobular cirrhosis
• History of thrombosis (excluding catheter-related thrombosis) or conditions associated with increased risk of thrombosis
• 18 years and older
• Confirmed diagnosis of cystic fibrosis (CF) and CF lung disease including:
• Sweat chloride ≥ 60 mmol/L
• Mutation Status * Bi-allelic mutations in the CFTR gene, or * Single mutation in the CFTR gene and clinical manifestations of CF lung disease
• Ineligible for CFTR modulator therapy, or previously received modulator therapy but discontinued due to adverse effects.
• Forced expiratory volume in 1 second (FEV1) ≥ 50% and ≤ 90% of predicted (per Global Lung Function Initiative) at Screening
• Resting oxygen saturation ≥ 92% on room air at Screening Key Inclusion Criteria (Sub-Study):
• 18 years and older
• Confirmed diagnosis of cystic fibrosis (CF) and CF lung disease including:
• Sweat chloride ≥ 60 mmol/L
• Mutation Status * Bi-allelic mutations in the CFTR gene, or * Single mutation in the CFTR gene and clinical manifestations of CF lung disease
• Currently on a stable dose of CFTR modulator therapy for a minimum of 60 days prior to Screening and agree to maintain current regimen through the 24-month Observation Period
• FEV1 ≥ 40% and \< 70% predicted (per Global Lung Function Initiative) at Screening, AND/OR experienced at least 2 pulmonary exacerbations in the last year requiring intravenous antibiotics Key Exclusion Criteria (Primary and Sub Study):
• Any prior gene therapy for any indication (Exception: mRNA-based or antisense oligonucleotide therapies are not exclusionary)
• Active Mycobacterium abscessus infection requiring ongoing treatment at Screening
• Active allergic bronchopulmonary aspergillosis requiring management with systemic corticosteroids or antifungal therapy
• Smoking (e.g. cigarettes, cigars, cannabis) or use of a vaping product during the 2 months prior to screening; must agree to not smoke or use vaping products during Screening and initial 24-month observation period.
• Contraindication to systemic corticosteroid therapy
• Requires chronic use of systemic corticosteroids or immunosuppressants to treat another condition
• If no known diagnosis of cystic fibrosis related diabetes (CFRD), Type I, or Type II diabetes: Hemoglobin A1C ≥ 6.5% at Screening
• If known diagnosis of CFRD, Type I or Type II diabetes: Hemoglobin A1C \> 7.5% at Screening
• Recent history of symptomatic hyperglycemia or unstable blood glucose levels as per Investigator's assessment
• Other conditions that, in the Investigator's opinion, may interfere with management of corticosteroid-related hyperglycemia
• Body Mass Index (BMI) \< 16
• Laboratory abnormalities at screening: * ALT, AST or GGT ≥ 3 × the upper limit of normal (ULN) * Total bilirubin ≥ 2 × ULN * Hemoglobin \< 10 g/dL
• Requirement for continuous or night-time oxygen supplementation
• Known CF liver disease with evidence of multilobular cirrhosis
• History of thrombosis (excluding catheter-related thrombosis) or conditions associated with increased risk of thrombosis
BIOLOGICAL: 4D-710
Cystic Fibrosis Lung
CF, Cystic Fibrosis, Gene Therapy
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Show 20 locations
Study Locations
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| Location | Contacts |
|---|---|
| Boston Children's Hospital Boston, Massachusetts | Monica Ulles - (monica.ulles@childrens.harvard.edu) |
| Johns Hopkins Hospital Baltimore, Maryland | Kaia Houtman - (khoutma1@jh.edu) |
| Massachusetts General Hospital Boston, Massachusetts | Margot Hardcastle - (mhardcastle@mgh.harvard.edu) |
| Medical University of South Carolina Charleston, South Carolina | Cameron Mathison - (mathisoc@musc.edu) |
| National Jewish Health Denver, Colorado | Jennifer Taylor-Cousar, MD - (TaylorCousarJ@NJHealth.org) Michele Gaffigan - (gaffiganm@njhealth.org) |
| Nationwide Children's Hospital Columbus, Ohio | Terri Johnson - (terri.johnson@nationwidechildrens.org) |
| Northwestern Memorial Hospital Chicago, Illinois | Rachel Nelson - (rachel.nelson@northwestern.edu) |
| Penn State Health Hershey, Pennsylvania | |
| Rainbow Babies and Children's Hospital/University Hospitals Cleveland Medical Center Cleveland, Ohio | Tia Rone - (Tia.Rone@uhhospitals.org) |
| The Hospital of the University of Pennsylvania Philadelphia, Pennsylvania | Melissa Molter - (melissa.molter@pennmedicine.upenn.edu) |
| The University of Arizona Tucson, Arizona | Elizabeth Ryan - (elizabethryan@arizona.edu) |
| The University of Texas Southwestern Medical Center Dallas, Texas | Maria McLeod - (maria.mcleod@utsouthwestern.edu) |
| University of Alabama Child Health Research Unit Birmingham, Alabama | Justin Anderson - (justinanderson@uabmc.edu) |
| University of California San Francisco San Francisco, California | Legna Betancourt - (legna.betancourt@ucsf.edu) |
| University of Florida Gainesville, Florida | Chrystal Bailey - (cbailey1@peds.ufl.edu) |
| University of Kansas Medical Center Kansas City, Kansas | Lawrence Scott - (lscott2@kumc.edu) |
| University of Miami Hospital Miami, Florida | Ivan Whitaker - (yiw2@miami.edu) |
| University of North Carolina at Chapel Hill Chapel Hill, North Carolina | |
| University of Washington Medical Center Seattle, Washington | Roshni Prabhu - (rprabhu@medicine.washington.edu) |
| Virginia Commonwealth University Health System Richmond, Virginia | Margaret K. Lessard - (margaret.lessard@vcuhealth.org) |
Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma (MelMarT-II)
Melanoma and Skin Cancer Trials Coordinator - melmart@masc.org.au
NCT03860883
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Inclusion Criteria:
Patients may be included in the study if they meet ALL of the following criteria:
• 1. Patients must have a Stage II primary invasive cutaneous melanoma (pT2b-pT4b, AJCC 8th edition) with Breslow thickness \>1.0mm to 2.0mm; \>2.0mm to 4.0mm or \>4.0mm with ulceration, or \>2.0mm to 4.0mm; or \>4.0mm without ulceration (Table 1) as determined by diagnostic biopsy (narrow excision, incision, shave or punch biopsy) and subsequent histopathological analysis.
• Must have a primary melanoma that is cutaneous (including head, neck, trunk, extremity, scalp, palm or sole).
• An uninterrupted 2cm margin must be technically feasible around biopsy scar or primary melanoma.
• 4. Surgical intervention (which refers to the staging -SLNB and WLE as these are both to be done on the same day) must be completed within 120 days of the original diagnosis. Surgical intervention must also be performed within 28 days of randomisation.
• Patients must be 18 years or older at time of consent.
• Patient must be able to give informed consent and comply with the treatment protocol and follow up plan.
• Life expectancy of at least 5 years from the time of diagnosis, not considering the melanoma in question, as determined by the PI.
• Patients must have an ECOG performance score between 0 and 1 at screening.
• A survivor of prior cancer is eligible provided that ALL of the following criteria are met and documented: * The patient has undergone potentially curative therapy for all prior malignancies, * There has been no evidence of recurrence of any prior malignancies for at least FIVE years (with the exception of successfully treated uterine/cervical or non-melanoma skin cancers (SCCs/BCCs) with no evidence of recurrence), and * The patient is deemed by their treating physician to be at low risk of recurrence from previous malignancies.
Exclusion Criteria:
Patients will be excluded from the study for ANY of the following reasons:
• Uncertain diagnosis of melanoma i.e., so-called 'melanocytic lesion of unknown malignant potential'.
• Patient has already undergone WLE at the site of the primary index lesion.
• Patient unable or ineligible to undergo staging SLNB of the primary index lesion.
• Perineural invasion or neurotropic melanoma: Neurotropism or perineural invasion in any type of melanoma is an exclusion. Perineural invasion does not include entrapment of nerves within the main primary tumour mass.
• Desmoplastic melanoma: with any patient where pathology determines melanoma as PURE desmoplastic (as per WHO definition of \>90% desmoplasia), they are not eligible for this study. However melanomas with less than 90% desmoplasia or mixed desmoplastic subtypes are eligible unless there is neurotropism present (perineural invasion).
• Microsatellitosis (a nest of metastatic tumour cells found to be growing away from the primary tumour) as per AJCC 8th edition definition is an exclusion.
• Subungual melanoma
• Patient has already undergone a local flap reconstruction of the defect after excision of the primary and determination of an accurate excision margin is impossible.
• History of previous or concurrent (i.e. \>1 primary melanoma) invasive melanoma.
• Melanoma located distal to the metacarpophalangeal joint; on the tip of the nose; the eyelids or on the ear; genitalia, perineum or anus; mucous membranes or internal viscera.
• Physical, clinical, radiographic or pathologic evidence of satellite, in-transit, regional, or distant metastatic melanoma.
• Patient has undergone surgery on a separate occasion to clear the lymph nodes of the probable draining lymphatic field, including -SLNB, of the index melanoma.
• Any additional solid tumour or hematologic malignancy during the past 5 years (with exception of non- melanoma skin cancers (T1 skin lesions of squamous cell carcinoma (SCCs), basal cell carcinoma (BCCs)), or uterine/cervical cancer).
• Melanoma-related operative procedures not corresponding to criteria described in the protocol.
• Planned adjuvant radiotherapy to the primary melanoma site after wide local excision is not permitted as part of the protocol and any patients given this treatment would be excluded from the study.
• History of organ transplantation.
• Oral or parenteral immunosuppressive agents (not topical or inhaled steroids) at enrolment or within 6 months prior to enrolment. Pregnancy is not a specific exclusion criterion for this trial, though it may not be clinically appropriate to perform a wide excision and SLNB until the pregnancy has been completed, which may exclude the patient due to violation of inclusion criterion 4. We would advise careful counselling of the patient prior to enrolling the patient, which would include a discussion at the treating centre's multidisciplinary team meeting or tumour board. We would strongly advise contacting the central trial office to discuss the case prior to enrolling on the study.
PROCEDURE: Wide Local Excision = 1cm Margin, PROCEDURE: Wide Local Excision = 2cm Margin
Cutaneous Melanoma, Stage II
Malignant, Melanoma, Cancer, Surgery
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See this study on ClinicalTrials.gov
Show 192 locations
Study Locations
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| Location | Contacts |
|---|---|
| AOU Città della Salute e della Scienza di Torino Torino, | |
| Advocate Illinois Masonic Medical Center Chicago, Illinois | Sigrun Hallmeyer - (sigrun.hallmeyer@aah.org) |
| Advocate Lutheran General Hospital Park Ridge, Illinois | Sigrun Hallmeyer, MD - (sigrun.hallmeyer@aah.org) Cheryl Korabik - (cheryl.korabik@aah.org) |
| Aurora St Luke's Medical Center Milwaukee, Wisconsin | Sigrun Hallmeyer - (sigrun.hallmeyer@aah.org) |
| BCCA - Cancer Centre for the Southern Interior Kelowna, British Columbia | Christopher Baliski - (cbaliski@bccancer.bc.ca) |
| Banner MD Anderson Cancer Center Gilbert, Arizona | Mark Gimbel - (mark.gimbel@bannerhealth.com) Sandra Ortega - (sandra.ortega@bannerhealth.com) |
| Baptist MD Anderson Cancer Center Jacksonville, Florida | Konstantinos Chouliaras - (Konstantinos.Chouliaras@bmcjax.com) |
| Calvary Public Hospital Bruce Bruce, Australian Capital Territory | |
| Cambridge University Hospitals NHS Foundation Trust Cambridge, England | Amit Roshan - (amit.roshan@addenbrookes.nhs.uk) |
| CancerCare Manitoba Winnipeg, Manitoba | |
| Carilion Roanoke Memorial Hospital Roanoke, Virginia | Giao Phan - (giao.phan@vcuhealth.org) Kristin Campbell - (klcampbell@vcu.edu) |
| Central Hospital Kristianstad Kristianstad, | Dr Karolin Isaksson - (karolin.isaksson@med.lu.se) |
| Centre Hospitalier de L'Universite de Montreal (CHUM) Montreal, Quebec | |
| Cooperman Barnabas Medical Center Livingston, New Jersey | Adam Berger - (ab2047@cinj.rutgers.edu) |
| Cork University Hospital Cork, | |
| Cox South Hospital Springfield, Missouri | |
| Diakonessenhuis Utrecht, | |
| Duke University Medical Center Durham, North Carolina | Jay Lee - (jay.lee@duke.edu) |
| East Carolina University Greenville, North Carolina | Nasreen Vohra - (joynersu@ecu.edu) |
| Emory Saint Joseph's Hospital Atlanta, Georgia | Michael Lowe, MD - (mlowe3@emory.edu) Charisse Ellis - (chariesse.aliyya.ellis@emory.edu) |
| Emory University Atlanta, Georgia | |
| Emory University Hospital Midtown Atlanta, Georgia | Michael Lowe, MD - (mlowe3@emory.edu) Rachel Mock - (rachel.ashley.mock@emory.edu) |
| Flevo Hospital Almere, Flevoland | - (gdiepenhorst@flevoziekenhuis.nl) |
| Fondazione IRCCS Policlinico San Matteo Pavia, | |
| Fox Chase Cancer Center Philadelphia, Pennsylvania | |
| Franciscan Health Indianapolis Indianapolis, Indiana | Juliana Meyer - (juliana.meyer@franciscanalliance.org) |
| Gelre Hospital Zutphen, Gelderland | Dominique van Uden, MD - (d.van.uden@gerle.nl) |
| Guthrie Medical Group PC-Robert Packer Hospital Sayre, Pennsylvania | David Bertsch, MD - (david.j.bertsch@guthrie.org) Susan Hadlock - (susan.hadlock@guthrie.org) |
| Guy's and St Thomas's NHS Foundation Trust, of St Thomas' Hospital London, | Jenny Geh, Ms - (Jenny.Geh@gstt.nhs.uk) |
| Hamilton Health Sciences Centre Hamilton, Ontario | |
| Hopital Maisonneuve-Rosemont Québec, | |
| Hotel-Dieu de Quebec Québec City, Quebec | Dr Cindy Boulanger-Gobeil - (cindy.boulanger-gobeil@chudequebec.ca) |
| Hull University Teaching Hospitals NHS Trust Cottingham, | Paolo Matteucci - (paolo.matteucci@hey.nhs.uk) |
| Huntington Memorial Hospital Pasadena, California | Mark Faries - (mfaries@theangelesclinic.org) |
| Huntsman Cancer Institute (The University of Utah) Salt Lake City, Utah | |
| IOV Istituto Oncologico Veneto IRCCS-Padova Padova, | |
| Imperial College Healthcare NHS Trust London, | Jonathon Dunne - (jonathan.dunne1@nhs.net) Mark Cabelles - (mark.cabelles@nhs.net) |
| Indiana University - Melvin and Bren Simon Cancer Center Indianapolis, Indiana | - (karlb@iu.edu) |
| Indiana University Melvin and Bren Simon Comprehensive Cancer Center Indianapolis, Indiana | Karl Bilimoria - (karlb@iu.edu) |
| Institute of Oncology Ljubljana Ljubljana, | |
| Intermountain Medical Center Murray, Utah | Tawnya Bowles - (tawnya.bowles@imail.org) Kevin Adams - (Kevin.Adams@imail.org) |
| Isala Hospital Zwolle, | |
| Kaiser Permanente - Vallejo Medical Center Vallejo, California | Tatjana Kolevska, MD - (Tatjana.Kolevska@kp.org) Desiree Goldstein - (desiree.goldstein@kp.org) |
| Kaiser Permanente - Walnut Creek Medical Center Walnut Creek, California | Tatjana Kolevska, MD - (Tatjana.Kolevska@kp.org) Desiree Goldstein - (desiree.goldstein@kp.org) |
| Kaiser Permanente Northwest - Oncology Clinic Portland, Oregon | Sandeep Mashru - (sandeep.h.mashru@kp.org) |
| Kaiser Sunnyside Medical Center Clackamas, Oregon | Sandeep Mashru - (sandeep.h.mashru@kp.org) |
| Lakeland Regional Health Hollis Cancer Center Lakeland, Florida | Manuel Molina - (manuel.molina@mylrh.org) |
| Lancashire Teaching Hospitals NHS Foundation Trust Preston, Lancashire | Richard Wain - (richard.wain@lthtr.nhs.uk) |
| Laura & Isaac Perlmutter Cancer Center at NYU Langone Health New York, New York | Erica Friedman - (mailto:Erica.Friedman@nyulangone.org) |
| Los Angeles General Medical Center Los Angeles, California | Gino In - (gino.in@med.usc.edu) |
| Los Angeles General Medical Center Los Angeles, California | Gino In, MD - (gino.in@med.usc.edu) |
| Lovelace Medical Centre-Saint Joseph Square Albuquerque, New Mexico | Bridget Fahy, MD - (BFahy@salud.unm.edu) |
| Lovelace Women's Hospital Albuquerque, New Mexico | Bridget Fahy, MD - (BFahy@salud.unm.edu) |
| MID & South Essex NHS Foundation Trust Westcliff on Sea, Essex | Prof Peter Dziewulski - (peter.dziewulski1@nhs.net) |
| Maastricht University Medical Center Maastricht, | Kevin Wevers - (Kevin.wevers@mumc.nl) |
| Marshfield Medical Center - Marshfield Marshfield, Wisconsin | Rohit Sharma - (sharma.rohit@marshfieldclinic.org) |
| Marshfield Medical Center- Weston Weston, Wisconsin | Rohit Sharma, MD - (sharma.rohit@marshfieldclinic.org) |
| Mater Misericordiae University Hospital Dublin, | Shirley Potter - (shirleypott@gmail.com) |
| Maxima Medical Center - Veldhoven Veldhoven, | |
| Maxima Medical Centre, Eindhoven Eindhoven, Noord-Brabant | |
| Mayo Clinic Phoenix Phoenix, Arizona | Barbara A Pockaj, MD - (pockaj.barbara@mayo.edu) Courtney Nelson - (Nelson.Courtney4@mayo.edu) |
| Mayo Clinic in Florida Jacksonville, Florida | James W Jakub - (Jakub.James@mayo.edu) |
| MedStar Franklin Square Medical Center Rosedale, Maryland | Edward McCarron - (edward.mccarron@medstar.net) |
| MedStar Georgetown University Hospital Washington D.C., District of Columbia | Geoffrey T Gibney - (geofrey.t.gibney@gunet.georgetown.edu) |
| Medical College of Wisconsin Milwaukee, Wisconsin | Jennifer Bruening - (jbruening@mcw.edu) Chloe Papageorgio - (cpapageorgio@mcw.edu) |
| Medical University of South Carolina Charleston, South Carolina | Andrea Abbott - (abbottan@musc.edu) |
| Medstar Washington Hospital Center Washington D.C., District of Columbia | Marc Boisvert, MD - (Marc.E.Boisvert@medstar.net) Nicolas Rojas - (Nicolas.Rojas@medstar.net) |
| Melanoma Institute Australia Sydney, New South Wales | |
| Memorial Sloan Kettering Cancer Center New York, New York | |
| Mercy Health Center - Oncology Hematology Oklahoma City, Oklahoma | Christian Ellis, DO - (christian.ellis@mercy.net) Trisha Strubhar - (trisha.strubhar@mercy.net) |
| Mercy Health Saint Mary's Grand Rapids, Michigan | Kathleen Yost - (kyost@crcwm.org) Renee Porter - (renee.porter@crcwm.org) |
| Miami Valley Hospital South Centerville, Ohio | James Ouellette - (jrouellett@premierhealth.com) |
| Moffitt Cancer Center - McKinley Campus Tampa, Florida | Jonathan Zager - (Jonathan.zager@moffitt.org) |
| Moffitt Cancer Center, Magnolia Campus Tampa, Florida | Jonathan Zager - (Jonathan.zager@moffitt.org) |
| NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center New York, New York | Bret Taback - (bt2160@cumc.columbia.ed) |
| NYU Langone Medical Center (Winthrop Hospital) Mineola, New York | Erica Friedman - (mailto:Erica.Friedman@nyulangone.org) |
| Nancy N and JC Lewis Cancer & Research Pavilion St. Joseph's/Candler Savannah, Georgia | Yana Puckett, MD - (drpucketty@sjchs.org) Stephanie Reyes - (smiths1@sjchs.org) |
| Nebraska Medicine - Bellevue Bellevue, Nebraska | Bradley Reames - (bradley.reames@unmc.edu) |
| Nebraska Medicine-Village Pointe Omaha, Nebraska | Bradley Reames - (bradley.reames@unmc.edu) |
| Norfolk and Norwich University Hospital NHS Trust Norwich, | |
| North Bristol NHS Trust Bristol, | Ewan Wilson, Mr - (Ewan.Wilson@nbt.nhs.uk) |
| North Shore Hospital Auckland, | |
| Northern Westchester Hospital Mount Kisco, New York | Alan Kadison - (Akadison@northwell.edu) |
| Northside Hospital Atlanta Atlanta, Georgia | Nicole Kounalakis - (nicole.kounalakis@northside.com) |
| Northside Hospital Cancer Institute Atlanta, Georgia | |
| Northwell Health Imbert Cancer Center Bay Shore, New York | Alan Kadison, MD - (akadison@northwell.edu) Diane Delliliune - (DDellili@northwell.edu) |
| Northwell Health/Center for Advanced Medicine Lake Success, New York | Alan Kadison, MD - (akadison@northwell.edu) Alexa Amoroso - (aamoroso1@northwell.edu) |
| Northwestern Medicine Cancer Center Delnor Geneva, Illinois | Jeffrey Wayne - (jeffrey.wayne@nm.org) |
| Northwestern Medicine Cancer Center Kishwaukee DeKalb, Illinois | Jeffrey Wayne - (jeffrey.wayne@nm.org) |
| Northwestern Medicine Cancer Center Lake Forest Hospital Lake Forest, Illinois | Jeffrey Wayne - (jeffrey.wayne@nm.org) |
| Northwestern Medicine Cancer Center Warrenville Warrenville, Illinois | Jeffrey Wayne - (jeffrey.wayne@nm.org) |
| Northwestern University Chicago, Illinois | Jeffrey Wayne - (jeffrey.wayne@nm.org) |
| Nottingham University Hospitals, NHS Trust, Trust HQ, City Hospital Nottingham, | Mr Jonathon Pollock - (Jonathan.Pollock@nuh.nhs.uk) |
| OUHSC Stephenson Cancer Center Oklahoma City, Oklahoma | William Dooley - (William-Dooley@ouhsc.edu) |
| Oak Valley Health Markham, Ontario | Jennifer Zhirui Li - (enli@oakvalleyhealth.ca) |
| Ohio State University Comprehensive Cancer Center Columbus, Ohio | Joal Joal - (Joal.Beane@osumc.edu) |
| Ottawa Hospital Research Institute Ottawa, Ontario | Dr. Carolyn Nessim - (cnessim@toh.ca) |
| Oxford University Hospitals NHS Foundation Trust Oxford, | - (oliver.cassell@ouh.nhs.uk) |
| Peter MacCallum Cancer Centre Melbourne, | |
| Phelps Memorial Hospital Center Sleepy Hollow, New York | Alan Kadison - (akadison@northwell.edu) |
| Princess Alexandra Hospital Woolloongabba, Queensland | |
| Queen Victoria Hospital NHS Foundation Trust East Grinstead, West Sussex | Siva Kumar - (siva.kumar1@nhs.net) |
| Robina Hospital Gold Coast, Queensland | |
| Roswell Park Cancer Institute Buffalo, New York | Shalana O'Brien - (shalana.obrien@roswellpark.org) |
| Royal Adelaide Hospital Adelaide, South Australia | Robert Whitfield - (Robert.Whitfield@sa.gov.au) |
| Royal Cornwall Hospital NHS Trust Truro, Cornwall | Polly King - (polly.king1@nhs.net) |
| Royal Free London NHS Foundation Trust London, | Steven Hamilton - (stephenhamilton@nhs.net) |
| Royal Prince Alfred Hospital Camperdown, New South Wales | |
| Royal Victoria Regional Health Centre Barrie, Ontario | Kelly Cruise - (cruisek@rvh.on.ca) |
| Rutgers Cancer Institute of New Jersey New Brunswick, New Jersey | |
| Sahlgrenska University Hospital Gothenburg, | Roger Olofsson Bagge - (roger.olofsson.bagge@gu.se) |
| Sanford Broadway Medical Centre Fargo, North Dakota | Preston Steen - (preston.steen@sanfordhealth.org) |
| Sanford Cancer Center Oncology Clinic Sioux Falls, South Dakota | Daniel Almquist, MD - (daniel.almquist@sanfordhealth.org) |
| Sanford Roger Maris Cancer Centre Fargo, North Dakota | Preston Steen - (preston.steen@sanfordhealth.org) |
| Sanford USD Medical Center - Sioux Falls Sioux Falls, South Dakota | Daniel Almquist, MD - (daniel.almquist@sanfordhealth.org) |
| Siteman Cancer Centre, Barnes Jewish West County Creve Coeur, Missouri | Ryan Fields - (rcfields@wustl.edu) |
| Smilow Hospital Care Center, Guilford Guilford, Connecticut | James Clune - (james.clune@yale.edu) |
| South Tees Hospitals NHS Foundation Trust of The James Cook University Hospital Middlesbrough, | Oliver Bassett, Mr - (o.bassett@nhs.net) |
| Spectrum Health at Butterworth Campus Grand Rapids, Michigan | Kathleen Yost - (Kyost@chcwm.com) |
| St George's University Hospitals NHS Foundation Trust London, | Joy Odili, Ms - (Joy.Odili@stgeorges.nhs.uk) |
| St James Hospital Dublin, | Marlese Dempsey - (marlesedempsey@gmail.com) |
| St Luke's University Health Network Quakertown Campus Quakertown, Pennsylvania | Darius Desai - (Darius.Desai@sluhn.org) |
| St Luke's University Health Network, Anderson Campus Easton, Pennsylvania | Darius Desai - (Darius.Desai@sluhn.org) |
| St Luke's University Health Network, Bethlehem Campus Bethlehem, Pennsylvania | Darius Desai - (Darius.Desai@sluhn.org) |
| St. Helens & Knowsley Teaching Hospitals NHS Trust Liverpool, | Rowan Pritchard Jones, Prof - (Rowan.PritchardJones@sthk.nhs.uk) |
| St. Luke's University Health Network - Allentown Cancer Center Allentown, Pennsylvania | Darius Desai, MD - (Darius.Desai@sluhn.org) Amy Grossman - (Amy.Grossman@sluhn.org) |
| St. Luke's University Health Network - Upper Bucks Quakertown, Pennsylvania | Darius Desai, MD - (Darius.Desai@sluhn.org) Amy Grossman - (Amy.Grossman@sluhn.org) |
| Stanford Cancer Center South Bay San Jose, California | |
| Stanford Cancer Institute Stanford, California | Amanda Kirane, MD FACS - (akirane@stanford.edu) Patrick Yuan - (yuanp@stanford.edu) |
| State University of New York Upstate Medical Center-Community Campus Syracuse, New York | Daniel Thomas, MD - (ThomasDa@upstate.edu) Laine Abernathy - (abernatl@upstate.edu) |
| State University of New York Upstate Medical University Syracuse, New York | Daniel Thomas, MD - (ThomasDa@upstate.edu) Laine Abernathy - (abernatl@upstate.edu) |
| Sunnybrook Health Sciences Centre Toronto, Ontario | |
| The Alfred Hospital Melbourne, Victoria | |
| The Angeles (Cedars-Sinai Medical Center and its Affiliates) Los Angeles, California | |
| The Canberra Hospital Garran, Australian Capital Territory | |
| The Christie NHS Foundation Trust Manchester, Lancashire | Deemesh Oudit - (deemesh.oudit@nhs.net) |
| The Leeds Teaching Hospitals NHS Trust Leeds, | Howard Peach, Mr - (h.peach@nhs.net) |
| The Royal Marsden Hospital NHS Foundation Trust London,, | Myles Smith - (Myles.Smith@rmh.nhs.uk) - (Myles.Smith@rmh.nhs.uk) |
| The University of Texas MD Anderson Cancer Center Houston, Texas | Jeffrey Gershenwald - (jgershen@mdanderson.org) |
| Tom Baker Cancer Centre Calgary, Alberta | |
| UC Irvine Health - Chao Family Comprehensive Cancer Center Orange, California | Jeremy Harris - (jpharris1@hs.uci.edu) |
| UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care Irvine, California | |
| UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care Irvine, California | Maki Yamamoto - (myamamot@hs.uci.edu) |
| UHN - Princess Margaret Cancer Centre Toronto, Ontario | Alexandra Easson, Dr - (Alexandra.Easson@uhn.ca) |
| USC Norris Comprehensive Cancer Center Los Angeles, California | Gino In - (gino.in@med.usc.edu) |
| USC Norris Comprehensive Cancer Center Los Angeles, California | Gino In, MD - (gino.in@med.usc.edu) |
| University Hospitals Avon Health Center Avon, Ohio | Luke Rothermel - (Luke.Rothermel@UHhospitals.org) |
| University Hospitals Birmingham NHS Foundation Trust Edgbaston, | Agustin Martin-Clavijo - (Agustin.Martin-Clavijo@uhb.nhs.uk) |
| University Hospitals Chagrin Highlands Medical Centre Orange Village, Ohio | Luke Rothermel - (Luke.Rothermel@UHhospitals.org) |
| University Hospitals Cleveland Medical Centre Cleveland, Ohio | Luke Rothermel - (Luke.Rothermel@UHhospitals.org) |
| University Hospitals Geauga Medical Center Chardon, Ohio | Luke Rothermel - (Luke.Rothermel@UHhospitals.org) |
| University Hospitals St. John Medical Center Westlake, Ohio | Luke Rothermel - (Luke.Rothermel@UHhospitals.org) |
| University Medical Centre Groningen Groningen, | Barbara Leeuwen - (b.l.van.leeuwen@umcg.nl) |
| University of Arkansas for Medical Sciences Little Rock, Arkansas | Michail Mavros - (MMavros@uams.edu) |
| University of Cincinnati Cincinnati, Ohio | Jeffrey Sussman - (sussmaj@ucmail.uc.edu) |
| University of Kansas Cancer Center Kansas City, Kansas | Luke Selby - (lselby@kumc.edu) |
| University of Kansas Hospital - Indian Creek Campus Overland Park, Kansas | Luke Selby - (lselby@kumc.edu) |
| University of Kansas Hospital- Westwood Cancer Center Westwood, Kansas | Luke Selby - (lselby@kumc.edu) |
| University of Kentucky Lexington, Kentucky | Erin Burke - (erin.burke@uky.edu) |
| University of Miami Comprehensive Cancer Center at Kendall Miami, Florida | Jessica S Crystal - (jxc2521@med.miami.edu) |
| University of Miami Comprehensive Cancer Center at Plantation Plantation, Florida | Jessica S Crystal - (jxc2521@med.miami.edu) |
| University of Miami Miller School of Medicine-Sylvester Cancer Centre Miami, Florida | Jessica S Crystal - (jxc2521@med.miami.edu) |
| University of Miami Sylvester Cancer Center at Coral Springs Coral Springs, Florida | Jessica S Crystal - (jxc2521@med.miami.edu) |
| University of Miami Sylvester Comprehensive Cancer Center at Aventura Aventura, Florida | Jessica S Crystal - (jxc2521@med.miami.edu) |
| University of Miami Sylvester Comprehensive Cancer Center at Coral Gables Coral Gables, Florida | Jessica S Crystal - (jxc2521@med.miami.edu) |
| University of Miami Sylvester Comprehensive Center at Deerfield Beach Deerfield Beach, Florida | Jessica S Crystal - (jxc2521@med.miami.edu) |
| University of Miami Sylvester Comprehensive Center at Hollywood Hollywood, Florida | Jessica S Crystal - (jxc2521@med.miami.edu) |
| University of Michigan - Brighton Center for Specialty Care Brighton, Michigan | Christina Angeles - (angelesc@med.umich.edu) |
| University of Michigan Medical Center Ann Arbor, Michigan | Christina Angeles - (angelesc@med.umich.edu) |
| University of Nebraska Medicine Omaha, Nebraska | Bradley Reames - (bradley.reames@unmc.edu) |
| University of North Carolina Hospitals - Hillsborough Campus Hillsborough, North Carolina | David Ollila - (david_ollila@med.unc.edu) |
| University of North Carolina at Chapel Hill Chapel Hill, North Carolina | David W Ollila - (david_ollila@med.unc.edu) |
| University of Rochester Rochester, New York | Paul Barr - (paul_barr@urmc.rochester.edu) |
| University of South Alabama Mitchell Cancer Institute Mobile, Alabama | John H Howard, MD - (jhoward@health.southalabama.edu) Tiffany Fulford - (tfulford@health.southalabama.edu) |
| University of Texas Health Science Center at San Antonio San Antonio, Texas | Fedrico Tozzi, MD - (tozzi@uthscsa.edu) Samantha Bankston - (bankstonsm@uthscsa.edu) |
| University of Vermont Medical Center Burlington, Vermont | Jessica Cintolo-Gonzalez, MD - (jessica.cintolo-gonzalez@uvmhealth.org) Elizabeth Abrecht - (elizabeth.abrecht@uvmhealth.org) |
| University of Vermount and Sate Agricultural College Burlington, Vermont | Jessica Cintolo-Gonzalez, MD - (jessica.cintolo-gonzalez@uvmhealth.org) Elizabeth Abrecht - (elizabeth.abrecht@uvmhealth.org) |
| University of Virginia Health System Charlottesville, Virginia | Lynn Dengel - (LTD5B@uvahealth.org) |
| University of Winsconsin Carbone Cancer Center-Eastpark medical Center Madison, Wisconsin | Heather Neuman - (neuman@surgery.wisc.edu) Heather Neuman, MD - (neuman@surgery.wisc.edu) |
| University of Wisconsin Carbone Cancer Center Madison, Wisconsin | Heather Neuman - (neuman@surgery.wisc.edu) Sam Hanson - (shhanson@wisc.ed) |
| VCU Massey Cancer Center Richmond, Virginia | Giao Phan - (giao.phan@vcuhealth.org) |
| VCU Massey Cancer Center Affiliate Valley Health Winchester, Virginia | Giao Phan - (giao.phan@vcuhealth.org) |
| VCU Massey Cancer Center Peninsula Cancer Institute Newport News, Virginia | Giao Phan - (giao.phan@vcuhealth.org) |
| Vassar Brothers Medical Center Poughkeepsie, New York | James Nitzkorski - (james.nitzkorski@nuvancehealth.org) Karley Flinn - (karley.flinn@nuvancehealth.org) |
| Washington University School of Medicine St Louis, Missouri | Ryan Fields - (rcfields@wustl.edu) |
| West Chester Hospital (OH394) West Chester, Ohio | Jeffrey Sussman - (sussmaj@ucmail.uc.edu) |
| West Michigan Cancer Centre Kalamazoo, Michigan | Kathleen Yost - (kyost@chcwm.com) |
| Westmead Hospital Westmead, New South Wales | Pablo Fernandez-Peñas - (pablo.fernandezpenas@sydney.edu.au) |
| Wilmont Cancer Institute at Webster Webster, New York | Paul Barr, MD - (paul_barr@urmc.rochester.edu) Sarah Cawley - (sarah_cawley@urmc.rochester.edu) |
| Yale University New Haven, Connecticut | James Clune - (james.clune@yale.edu) |
| Ziekenhuis Gelderse Vallei Ede, Gelderland | Miriam L Hoven-Gondrie - (HovenM@zgv.nl) |
| Zuyderland Medical Center Sittard-Geleen, |
LGMD R1 Natural History Study (GRASP-01-003)
Ruby Langeslay - ruby.langeslay@vcuhealth.org
NCT05618080
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Inclusion Criteria:
• Age between 12-50 at enrollment
• Clinically affected (defined as weakness on bedside evaluation in a pattern consistent with LGMDR1)
• Genetic confirmation of LGMDR1 (presence of homozygous or compound heterozygous pathogenic mutations in CAPN3).
• Must be able to provide written informed consent and be willing and able to comply with all study requirements. Note: Adult participants must be able to provide consent themselves. Legally authorized representatives are not permitted to consent on behalf of adult participants.
Exclusion Criteria:
• Have contraindications to MRI or MRS (e.g., non-MR compatible implanted medical devices or severe claustrophobia)
• Non-ambulatory as defined by those who are not able to walk 10 meters without assistive devices (ankle foot orthotics excluded)
• Positive pregnancy test at any timepoint during the trial
• Have dominantly inherited CAPN3 mutations (LGMDD4)
• Any other illness that would interfere with the ability to undergo safe testing or would interfere with interpretation of the results in the opinion of the site investigator.
Calpain-3 Deficiency Limb Girdle Muscular Dystrophy Type 2A, Limb Girdle Muscular Dystrophy, Limb Girdle Muscular Dystrophy Type R1, LGMD2A
LGMD, Limb Girdle Muscular Dystrophy, LGMD R1, LGMD2A, CAPN3
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Show 12 locations
Study Locations
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| Location | Contacts |
|---|---|
| Leiden University Medical Center Leiden, | Marjolein van Heur - (m.j.van_heur-neuman@lumc.nl) Anne-Marie Peters - (a.m.g.h.Peters@lumc.nl) |
| Nationwide Children's Hospital Columbus, Ohio | Audrey Knight - (audrey.knight@nationwidechildrens.org) Lauren Humphrey - (lauren.humphrey@nationwidechildrens.org) |
| Newcastle University Newcastle upon Tyne, Tyne and Wear | Sonia Segovia - (sonia.segovia@newcastle.ac.uk) |
| The Community Health Clinic, Inc. Shipshewana, Indiana | Grace Lewis - (glewis@indianachc.org) |
| University of California, Irvine Irvine, California | Siddhant Pratap - (spratap1@hs.uci.edu) Isela Hernandez - (iselah@hs.uci.edu) |
| University of Colorado Anschutz Medical Campus Aurora, Colorado | Alyssa Avilez - (alyssa.avilez@cuanschutz.edu) Talia Strahler - (talia.strahler@cuanschutz.edu) |
| University of Florida Gainesville, Florida | Yara Mohammed, MD, MPH - (yaramohamed@peds.ufl.edu) |
| University of Iowa Hospitals and Clinics Iowa City, Iowa | Chandra Miller - (chandra-miller@uiowa.edu) Carrie Stephan - (carrie-stephan@uiowa.edu) |
| University of Kansas Medical Center Kansas City, Kansas | Rebecca Clay - (rclay@kumc.edu) |
| University of Minnesota, Department of Neurology Minneapolis, Minnesota | Allison Johnston - (joh21779@umn.edu) |
| Virginia Commonwealth University Richmond, Virginia | Levi Headrick - (levi.headrick@vcuhealth.org) Anarosa, Rezeq - (anarosa.rezeq@vcuhealth.org) |
| Washington University School of Medicine St Louis, Missouri | Olivia Money - (moneyo@wustl.edu) |
Periaqueductal Gray-vagus Nerve Interface Malfunction Explain the Natural History With Its Numerous Co-morbidities?
Gisela Chelimsky, M.D. - gisela.chelimsky@vcuhealth.org
NCT05618054
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Inclusion Criteria:
* Females 12-21 years old
* Able to communicate and provide consent/assent
* English speaking
* Diagnosed with POTS (POTS will be defined standardly as a symptomatic ≥ 40 bpm rise in heart rate without a drop in blood pressure and with symptoms of orthostatic intolerance clinically)
* Age-matched healthy control subjects: no POTS or other neurological disorders
Exclusion Criteria:
* Inflammatory arthritis, connective tissue or auto-immune disorder
* Any chronic neurological disorder besides POTS
* Evidence of unstable medical disorder, such as kidney (rising creatinine, or end-stage renal failure) or liver impairment (rising AST or ALT, or end-stage with coagulopathy), poorly controlled significant cardiovascular (CHF), respiratory, endocrine (diabetes - A1c \> 9 - or untreated thyroid dysfunction) or uncontrolled psychiatric illness (such as untreated depression, psychosis, etc.)
* Neuropathy, central nervous system disorder (e.g., Cerebral palsy, developmental delay, seizure disorder, MS, stroke, etc.)
* Treatment with a drug or medical device within the previous 30 days that has not received regulatory approval
* Use of hormones (except insulin, thyroid replacement or oral contraceptives, which will be carefully documented)
* Current substance or alcohol abuse
* Any major surgical intervention with general anesthesia in the last 60 days and minor procedure, such as tooth extraction, endoscopy, etc., with local or conscious sedation within 7 days
* Any on-going or pending medical, health or disability related litigation, or current pursuit of disability
* Any condition that in the judgment of the investigator would interfere with the patient's ability to provide informed consent, comply with study instructions, place the patient at increased risk, or which would clearly confound the interpretation of the study results (specific reason will be documented)
* Chronic use of narcotics for pain
* Claustrophobia or any metal hardware that may interfere with MRI
* Investigators and study staff BEHAVIORAL: Looming task
Postural Tachycardia Syndrome
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Show 1 location
Study Locations
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia |
Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer
ctrrecruit@vcu.edu
NCT05172245
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Inclusion Criteria:
* Patients must have pathologically confirmed HNSCC (including tumors of the oropharynx, hypopharynx, larynx, oral cavity, nasal cavity, maxillary and other paranasal sinuses, and unknown primary of the head and neck), with measurable disease as per RECIST 1.1
* Oropharyngeal and unknown primary squamous cell cancers must test for human papilloma virus (HPV), for example by p16 immunohistochemistry (IHC), in situ hybridization (ISH), or polymerase chain reaction (PCR). HPV testing is not required for other HNSCC primary tumor sites
* Patients with p16-positive tumors are eligible if M0 and any of one the following: cT4 or cN3 or cT2-3N2 or imaging-detected extranodal extension (iENE) according to the American Joint Committee on Cancer (AJCC)/TNM Staging System, 8th or 9th edition (Ed.)
* Patients with p16-negative (or not tested) tumors are eligible if clinical stage III-IVB (locally advanced but non-metastatic) according to the AJCC/TNM Staging System, 8th or 9th Ed.
* Must be candidate for concurrent, definitive cisplatin and radiation therapy as judged by the treating physician
* Able to swallow tablets at the time of enrollment
* Age \>= 18 years. Because no dosing or adverse event data are currently available on the use of ipatasertib in combination with chemoradiation in patients \< 18 years of age, children are excluded from this study
* Eastern Cooperative Oncology Group (ECOG) performance status 0-1
* Life expectancy of greater than 3 months
* Absolute neutrophil count \>= 3000/mcL
* Hemoglobin \>= 10 g/dL
* Platelets \>= 150,000/mcL
* Serum albumin \>= 3 g/dL
* Total bilirubin =\< 1.5 x institutional upper limit of normal (ULN)
* Aspartate aminotransferase (AST) (serum glutamic oxaloacetic transaminase \[SGOT\])/alanine aminotransferase (ALT) (serum glutamate pyruvate transaminase \[SGPT\]) =\< 2.5 x institutional ULN / 2 x institutional ULN
* Alkaline phosphatase (ALP) =\< 2.0 x institutional ULN
* Partial thromboplastin time (PTT) (or activated \[a\]PTT) and international normalized ratio (INR) =\< 1.5 institutional ULN (except for patients receiving anticoagulation therapy)
* Creatinine clearance (CLcr) \> 60 mL/min
* For this calculation, use the Cockroft-Gault formula
* Fasting glucose =\< 150 mg/dL (8.3 mmol/L) and (when indicated) glycosylated hemoglobin (HbA1c ) =\< 7.5% (58 mmol/mol)
* Human immunodeficiency virus (HIV)-infected patients are eligible if on effective anti-retroviral therapy with undetectable viral load within 6 months
* Patients with past hepatitis B virus (HBV) infection or resolved HBV infection (defined as having a negative hepatitis B virus surface antigen \[HBsAg\] test and a positive hepatitis B core antibody \[HBcAb\] test, accompanied by a negative HBV deoxyribonucleic acid \[DNA\] test) are eligible. Patients with chronic HBV infection are eligible if the HBV viral load is undetectable on suppressive therapy, if indicated. Patients undergoing current treatment with anti-viral therapy for HBV are ineligible
* Patients with a history of hepatitis C virus (HCV) infection are eligible only if polymerase chain reaction (PCR) is negative for HCV ribonucleic acid (RNA). Patients with HCV infection who are currently on treatment are eligible if they have an undetectable HCV viral load
* Patients with a prior or concurrent malignancy whose natural history or treatment does not have the potential to interfere with the safety or efficacy assessment of the investigational regimen are eligible for this trial
* The effects of ipatasertib on the developing human fetus are unknown. For women of childbearing potential: agreement to remain abstinent (refrain from heterosexual intercourse) or use contraceptive methods with a failure rate of \< 1% per year during the treatment period and for at least 28 days after the last dose of ipatasertib and agreement to refrain from donating eggs during this same period. For men: agreement to remain abstinent (refrain from heterosexual intercourse) or use contraceptive measures, and agreement to refrain from donating sperm during the treatment period and for 28 days after the last dose of ipatasertib
* Ability to understand and the willingness to sign a written informed consent document
* For the expansion cohort only, there is a mandatory ask of patients to consider undergoing on-treatment biopsies
Exclusion Criteria:
* Primary tumor of nasopharynx, salivary, thyroid or parathyroid glands, or skin
* Distant metastases from the current HNSCC
* Prior treatment (e.g., chemotherapy, radiation, or definitive surgery) for the current locally advanced HNSCC is not permitted. Biopsies, including those performed under anesthesia, are not considered surgery. Patients who underwent prior definitive surgery alone for an early stage (T1-2N0) HNSCC which has now recurred with stage III-IVB disease at least 3 months after the initial surgery are eligible
* For patients with a prior history of another malignancy, no prior chemotherapy or radiation may have been administered within 6 weeks prior to study entry. Among patients who received prior radiation to the head and neck or adjacent anatomical site for another malignancy, there may be no overlap with current area to be irradiated
* Current use of any other investigational agents
* History of allergic reactions attributed to compounds of similar chemical or biologic composition to ipatasertib or other agents used in study
* Treatment with strong inhibitors or inducers of CYP3A4 or P-glycoprotein within 2 weeks or 5 drug-elimination half-lives, whichever is longer, prior to initiation of study drug. Because the lists of these agents are constantly changing, it is important to regularly consult a frequently-updated medical reference. As part of the enrollment/informed consent procedures, the patient will be counseled on the risk of interactions with other agents, and what to do if new medications need to be prescribed or if the patient is considering a new over-the-counter medicine or herbal product
* Patients with uncontrolled intercurrent illness, including active infection
* Pregnant women are excluded from this study because ipatasertib is an oral AKT inhibitor with the potential for teratogenic or abortifacient effects. Because there is an unknown but potential risk for adverse events in nursing infants secondary to treatment of the mother with ipatasertib, breastfeeding should be discontinued if the mother is treated with ipatasertib. These potential risks may also apply to other agents used in this study
* Patients with type I or type II diabetes mellitus requiring insulin at study entry. Patients with non-insulin dependent type II diabetes mellitus are eligible, as are patients who are on a stable dose of oral diabetes medication \>= 4 weeks prior to initiation of study treatment. Patients with a history of diabetes mellitus, an abnormal fasting glucose level, or other signs or symptoms indicating diabetes mellitus, must meet the laboratory eligibility criteria for fasting blood glucose and hemoglobin A1c
* History of or active inflammatory bowel disease (e.g., Crohn's disease and ulcerative colitis) or active bowel inflammation (e.g., diverticulitis)
* History of malabsorption syndrome or other condition that would interfere with enteral absorption or results in the inability or unwillingness to swallow pills
* Lung disease: pneumonitis, interstitial lung disease, idiopathic pulmonary fibrosis, cystic fibrosis, aspergillosis, active tuberculosis, or history of opportunistic infections (pneumocystis pneumonia or cytomegalovirus pneumonia)
* Known clinically significant history of liver disease consistent with Child Pugh Class B or C, including active viral or other hepatitis (e.g., positive for hepatitis B surface antigen \[HBsAg\] or hepatitis C virus \[HCV\] antibody at screening), or cirrhosis
* Grade \>= 2 uncontrolled or untreated hypercholesterolemia (cholesterol \> 300 mg/dL or \> 7.75 mmol/L) or hypertriglyceridemia (triglycerides \> 300 mg/dL or \> 3.42 mmol/L) PROCEDURE: Biopsy Procedure, PROCEDURE: Biospecimen Collection, DRUG: Cisplatin, PROCEDURE: Computed Tomography, DRUG: Ipatasertib, PROCEDURE: Magnetic Resonance Imaging, PROCEDURE: Positron Emission Tomography, RADIATION: Radiation Therapy
Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Head and Neck Carcinoma of Unknown Primary, Locally Advanced Head and Neck Squamous Cell Carcinoma, Locally Advanced Hypopharyngeal Squamous Cell Carcinoma, Locally Advanced Laryngeal Squamous Cell Carcinoma, Locally Advanced Nasal Cavity Squamous Cell Carcinoma, Locally Advanced Oral Cavity Squamous Cell Carcinoma, Locally Advanced Oropharyngeal Squamous Cell Carcinoma, Locally Advanced Paranasal Sinus Squamous Cell Carcinoma, Locally Advanced Sinonasal Squamous Cell Carcinoma, Maxillary Sinus Squamous Cell Carcinoma, Stage III Hypopharyngeal Carcinoma AJCC v8, Stage III Laryngeal Cancer AJCC v8, Stage III Lip and Oral Cavity Cancer AJCC v8, Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8, Stage III Sinonasal Cancer AJCC v8, Stage IVA Hypopharyngeal Carcinoma AJCC v8, Stage IVA Laryngeal Cancer AJCC v8, Stage IVA Lip and Oral Cavity Cancer AJCC v8, Stage IVA Oropharyngeal (p16-Negative) Carcinoma AJCC v8, Stage IVA Sinonasal Cancer AJCC v8, Stage IVB Hypopharyngeal Carcinoma AJCC v8, Stage IVB Laryngeal Cancer AJCC v8, Stage IVB Lip and Oral Cavity Cancer AJCC v8, Stage IVB Oropharyngeal (p16-Negative) Carcinoma AJCC v8, Stage IVB Sinonasal Cancer AJCC v8
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Show 18 locations
Study Locations
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| Location | Contacts |
|---|---|
| Atrium Health Cabarrus/LCI-Concord Concord, North Carolina | |
| Carolinas Medical Center/Levine Cancer Institute Charlotte, North Carolina | |
| Moffitt Cancer Center Tampa, Florida | Site Public Contact - (ClinicalTrials@moffitt.org) |
| Montefiore Medical Center - Moses Campus The Bronx, New York | Site Public Contact - (eskwak@montefiore.org) |
| Montefiore Medical Center-Einstein Campus The Bronx, New York | Site Public Contact - (eskwak@montefiore.org) |
| Northwestern University Chicago, Illinois | Site Public Contact - (cancer@northwestern.edu) |
| Rutgers Cancer Institute of New Jersey New Brunswick, New Jersey | |
| Rutgers New Jersey Medical School Newark, New Jersey | |
| University Health Network-Princess Margaret Hospital Toronto, Ontario | |
| University of Cincinnati Cancer Center-UC Medical Center Cincinnati, Ohio | Site Public Contact - (cancer@uchealth.com) |
| University of Cincinnati Cancer Center-West Chester West Chester, Ohio | Site Public Contact - (cancer@uchealth.com) |
| University of Kansas Cancer Center Kansas City, Kansas | Site Public Contact - (KUCC_Navigation@kumc.edu) |
| University of Kansas Clinical Research Center Fairway, Kansas | Site Public Contact - (KUCC_Navigation@kumc.edu) |
| University of Kansas Hospital-Westwood Cancer Center Westwood, Kansas | Site Public Contact - (KUCC_Navigation@kumc.edu) |
| University of Kentucky/Markey Cancer Center Lexington, Kentucky | |
| University of Maryland/Greenebaum Cancer Center Baltimore, Maryland | |
| University of Virginia Cancer Center Charlottesville, Virginia | |
| VCU Massey Comprehensive Cancer Center Richmond, Virginia | Site Public Contact - (CTOclinops@vcu.edu) |
Prophylaxis With Direct-acting Antivirals for Kidney Transplantation From HCV-Infected Donors to Uninfected Recipients (PREVENT-HCV)
Christine Durand, MD - cdurand2@jhmi.edu
NCT05653232
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Inclusion Criteria:
* Participant meets the standard criteria for KT at local center.
* Participant is able to understand and provide informed consent.
* Participant is ≥ 18 years old.
Exclusion Criteria:
* Participant has active HCV infection (detectable HCV RNA) at time of screening.
* Participant has cirrhosis or advanced liver fibrosis.
* Participant's aspartate aminotransferase (AST) or ALT \> 2.5 times the upper limit of normal (ULN), within 60 days of screen.
* Participant has human immunodeficiency virus infection (HIV), or active hepatitis B (HBV) infection.
* Participant is unable to safely substitute or discontinue a medication that is contraindicated with the study medication.
* Past or current medical problems, which may pose additional risks from participation in the study, interfere with the participant's ability to comply with study, or impact the quality of the data obtained from the study.
* Participant is pregnant or breastfeeding. OTHER: Prophylaxis (P2W), OTHER: Transmit and Treat (T&T)
HCV
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Show 9 locations
Study Locations
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| Location | Contacts |
|---|---|
| Icahn School of Medicine at Mount Sinai New York, New York | Susan Lerner, MD - (Susan.Lerner@mountsinai.org) |
| Johns Hopkins University Columbia, Maryland | Christine Durand, MD - (cdurand2@jhmi.edu) |
| Loma Linda University Health Loma Linda, California | Mina Rakoski, MD - (mrakoski@llu.edu) |
| NYU Langone Health New York, New York | Aprajita Mattoo, MD - (Aprajita.Matoo@nyulangone.org) |
| University of California San Diego La Jolla, California | Saima Aslam, MD - (saslam@ucsd.edu) |
| University of Pittsburgh Medical Center Pittsburgh, Pennsylvania | Fernanda Silveira, MD - (silvfd@upmc.edu) |
| University of Utah Medical Center Salt Lake City, Utah | |
| University of Wisconsin, Madison Madison, Wisconsin | |
| Virginia Commonwealth University Richmond, Virginia | Gaurav Gupta, MD - (gaurav.gupta@vcuhealth.org) |
A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT
ctrrecruit@vcu.edu
NCT04684368
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Inclusion Criteria:
* Patients must be \>= 3 years and \< 30 years at the time of study enrollment
* Patients must be newly diagnosed with localized primary CNS NGGCT of the suprasellar and/or pineal region by pathology and/or serum or cerebrospinal fluid (CSF) elevation of AFP above institutional normal or \> 10 ng/mL or human chorionic gonadotropin (hCG) beta \> 100 mIU/mL as confirmed by Rapid Central Marker Screening Review on APEC14B1-CNS. Suprasellar, pineal and bifocal tumors are included. (CSF tumor markers and cytology must be within 31 days prior to enrollment and start of protocol therapy \[repeat if necessary\]. Serum tumor markers, AFP and hCGbeta must be within 7 days prior to enrollment and start of protocol therapy \[repeat if necessary\]). Basal ganglia or other primary sites are excluded
* Patients with any of the following pathological elements are eligible: endodermal sinus (yolk sac), embryonal carcinoma, choriocarcinoma, malignant/immature teratoma and mixed germ cell tumor (GCT) (i.e., may include some pure germinoma) if malignant elements listed above are present. Patients with only mature teratoma are excluded. Patients with pure germinoma admixed with mature teratoma are excluded (would be eligible for pure germinoma protocols)
* Patients must have a cranial MRI with and without gadolinium at diagnosis/prior to enrollment. If surgical resection is performed, patients must have pre-operative and post operative brain MRI with and without gadolinium. Note: The post operative brain MRI should be obtained within 72 hours of surgery. If patient has a biopsy only, post-operative brain MRI is recommended but not required (within 31 days prior to study enrollment and start of protocol therapy - Note: for patients that have had surgery and post-operative imaging performed, it is the post-operative MRI following definitive surgery that must be obtained within 31 days prior to enrollment)
* Patients must have a spine MRI with gadolinium obtained at diagnosis/prior to enrollment. Spine MRI with and without gadolinium is recommended (within 31 days prior to study enrollment and start of protocol therapy - Note: for patients that have had surgery and post-operative imaging performed, it is the post-operative MRI following definitive surgery that must be obtained within 31 days prior to enrollment)
* Lumbar CSF must be obtained prior to study enrollment unless medically contraindicated. Note: False positive cytology can occur within 10 days of surgery. If lumbar CSF for cytology is not performed prior to surgery, then it should be performed at least 10 days following surgery and prior to study enrollment. Patients with negative CSF cytology from lumbar puncture obtained 1 to 10 days after surgery do not need cytology repeated
* Patients must have RAPID CENTRAL TUMOR MARKER REVIEW CSF tumor markers obtained prior to enrollment unless medically contraindicated. Ventricular CSF obtained at the time of CSF diversion procedure (if performed) is acceptable for tumor markers but lumbar CSF is preferred. In case CSF diversion and biopsy/surgery are combined, CSF tumor markers should be collected first
* Peripheral absolute neutrophil count (ANC) \>= 1000/uL (within 7 days prior to enrollment)
* Platelet count \>= 100,000/uL (transfusion independent) (within 7 days prior to enrollment)
* Hemoglobin \>= 8.0 g/dL (may receive red blood cell \[RBC\] transfusions) (within 7 days prior to enrollment)
* Creatinine clearance or radioisotope glomerular filtration rate (GFR) \>= 70 mL/min/1.73 m\^2 or a serum creatinine based on age/sex as follows (within 7 days prior to enrollment):
* Age: Maximum serum creatinine (mg/dL)
* 3 to \< 6 years: 0.8 (male), 0.8 (female)
* 6 to \< 10 years: 1 (male), 1 (female)
* 10 to \< 13 years: 1.2 (male), 1.2 (female)
* 13 to \< 16 years: 1.5 (male), 1.4 (female)
* \>= 16 years: male (1.7), 1.4 (female)
* Total bilirubin =\< 1.5 x upper limit of normal (ULN) for age (within 7 days prior to enrollment)
* Serum glutamate pyruvate transaminase (SGPT) (alanine aminotransferase \[ALT\]) =\< 135 U/L (within 7 days prior to enrollment)
* Note: For the purpose of this study, the ULN for SGPT (ALT) has been set to the value of 45 U/L
* Central nervous system function defined as:
* Patients with seizure disorder may be enrolled if on anticonvulsants and well controlled
* Patients must not be in status epilepticus, coma or assisted ventilation prior to study enrollment
* Protocol therapy must begin within 31 calendar days of definitive surgery or clinical diagnosis, whichever is later. If a biopsy only was performed, the biopsy date will be considered the date of definitive surgery. For patients who have a biopsy or incomplete resection at diagnosis followed by additional surgery, the date of the last resection will be considered the date of definitive surgery.
* All patients and/or their parents or legal guardians must sign a written informed consent
* All institutional, Food and Drug Administration (FDA), and National Cancer Institute (NCI) requirements for human studies must be met
* NEUROCOGNITIVE FUNCTION AND QUALITY OF LIFE ASSESSMENT:
* English-, Spanish-, or French- speaking
* Note: Patients who speak a language other than English, Spanish, or French will be allowed to participate in ACNS2021 but will not complete the neurocognitive and quality of life assessments
* No known history of neurodevelopmental disorder prior to diagnosis of NGGCT (e.g., Down syndrome, fragile X, William syndrome, intellectual disability). Patients with NF1 will be allowed to participate
* Additional eligibility criteria for the COG Standardized Neuropsychological Battery only: must be at a site that has a psychologist to administer the battery
* Note: If not eligible for the COG Standardized Battery, patients should still complete the Behavior Rating Inventory of Executive Function, Second Edition (BRIEF-2), Pediatric Quality of Life Inventory (PedsQL), Adaptive Behavior Assessment System Third Edition (ABAS-3), and Behavior Assessment System for Children, Third Edition (BASC-3) questionnaires
Exclusion Criteria:
* Patients with tumors located outside the ventricles (i.e., basal ganglia, thalamus)
* Patients with only mature teratoma and non-elevated markers upon tumor sampling at diagnosis
* Patients who have received any prior tumor-directed therapy for their diagnosis of NGGCT other than surgical intervention and corticosteroids
* Patients with metastatic disease (i.e., MRI evaluation, lumbar CSF cytology or intraoperative evidence of dissemination)
* Female patients who are pregnant, since fetal toxicities and teratogenic effects have been noted for several of the study drugs
* Note: Serum and urine pregnancy tests may be falsely positive due to HCGbeta-secreting germ cell tumors. Ensure the patient is not pregnant by institutional standards
* Lactating females who plan to breastfeed their infants
* Sexually active patients of reproductive potential who have not agreed to use an effective contraceptive method for the duration of their study participation PROCEDURE: Biospecimen Collection, DRUG: Carboplatin, DRUG: Etoposide, BIOLOGICAL: Filgrastim, DRUG: Ifosfamide, PROCEDURE: Magnetic Resonance Imaging, DRUG: Mesna, BIOLOGICAL: Pegfilgrastim, PROCEDURE: Peripheral Blood Stem Cell Transplantation, OTHER: Questionnaire Administration, RADIATION: Radiation Therapy, RADIATION: Radiation Therapy, PROCEDURE: Second-Look Surgery, DRUG: Thiotepa
Central Nervous System Nongerminomatous Germ Cell Tumor, Choriocarcinoma, Embryonal Carcinoma, Immature Teratoma, Malignant Teratoma, Mixed Germ Cell Tumor, Pineal Region Germ Cell Tumor, Pineal Region Immature Teratoma, Pineal Region Yolk Sac Tumor, Suprasellar Germ Cell Tumor
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Show 170 locations
Study Locations
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| Location | Contacts |
|---|---|
| Albany Medical Center Albany, New York | |
| Alberta Children's Hospital Calgary, Alberta | Site Public Contact - (research4kids@ucalgary.ca) |
| Alfred I duPont Hospital for Children Wilmington, Delaware | Site Public Contact - (Allison.bruce@nemours.org) |
| Alliance for Childhood Diseases/Cure 4 the Kids Foundation Las Vegas, Nevada | |
| Arkansas Children's Hospital Little Rock, Arkansas | |
| Arnold Palmer Hospital for Children Orlando, Florida | Site Public Contact - (Jennifer.spinelli@orlandohealth.com) |
| BI-LO Charities Children's Cancer Center Greenville, South Carolina | Site Public Contact - (Kim.Williams3@prismahealth.org) |
| Banner Children's at Desert Mesa, Arizona | |
| Banner University Medical Center - Tucson Tucson, Arizona | Site Public Contact - (UACC-IIT@uacc.arizona.edu) |
| Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center Houston, Texas | Site Public Contact - (burton@bcm.edu) |
| Blank Children's Hospital Des Moines, Iowa | Site Public Contact - (samantha.mallory@unitypoint.org) |
| British Columbia Children's Hospital Vancouver, British Columbia | |
| C S Mott Children's Hospital Ann Arbor, Michigan | |
| CHU de Quebec-Centre Hospitalier de l'Universite Laval (CHUL) Québec, | Site Public Contact - (rechclinique@crchudequebec.ulaval.ca) |
| Cancer Care Specialists - Reno Reno, Nevada | |
| CancerCare Manitoba Winnipeg, Manitoba | Site Public Contact - (ctu_web@cancercare.mb.ca) |
| Cardinal Glennon Children's Medical Center St Louis, Missouri | |
| Carilion Children's Roanoke, Virginia | Site Public Contact - (wpmccarty@carilionclinic.org) |
| Carolinas Medical Center/Levine Cancer Institute Charlotte, North Carolina | |
| Cedars-Sinai Medical Center Los Angeles, California | Site Public Contact - (Cancer.trial.info@cshs.org) |
| Centre Hospitalier Universitaire Sainte-Justine Montreal, Quebec | Site Public Contact - (yvan.samson@umontreal.ca) |
| Centre Hospitalier Universitaire de Sherbrooke-Fleurimont Sherbrooke, Quebec | Site Public Contact - (crcinformation.chus@ssss.gouv.qc.ca) |
| Children's Healthcare of Atlanta - Arthur M Blank Hospital Atlanta, Georgia | Site Public Contact - (Olivia.Floyd@choa.org) |
| Children's Hospital Colorado Aurora, Colorado | Site Public Contact - (josh.b.gordon@nsmtp.kp.org) |
| Children's Hospital Los Angeles Los Angeles, California | |
| Children's Hospital Medical Center Of Akron Akron, Ohio | |
| Children's Hospital and Medical Center of Omaha Omaha, Nebraska | |
| Children's Hospital of Alabama Birmingham, Alabama | |
| Children's Hospital of Michigan Detroit, Michigan | Site Public Contact - (helpdesk@childrensoncologygroup.org) |
| Children's Hospital of Orange County Orange, California | Site Public Contact - (oncresearch@choc.org) |
| Children's Hospital of Pittsburgh of UPMC Pittsburgh, Pennsylvania | Site Public Contact - (jean.tersak@chp.edu) |
| Children's Hospital of San Antonio San Antonio, Texas | Site Public Contact - (bridget.medina@christushealth.org) |
| Children's Hospital of the King's Daughters Norfolk, Virginia | Site Public Contact - (CCBDCresearch@chkd.org) |
| Children's Hospitals and Clinics of Minnesota - Minneapolis Minneapolis, Minnesota | Site Public Contact - (pauline.mitby@childrensmn.org) |
| Children's Mercy Hospitals and Clinics Kansas City, Missouri | Site Public Contact - (COGResearchGroup@cmh.edu) |
| Children's National Medical Center Washington D.C., District of Columbia | Site Public Contact - (OncCRC_OnCall@childrensnational.org) |
| Christchurch Hospital Christchurch, | |
| Cincinnati Children's Hospital Medical Center Cincinnati, Ohio | Site Public Contact - (cancer@cchmc.org) |
| Cleveland Clinic Foundation Cleveland, Ohio | |
| Connecticut Children's Medical Center Hartford, Connecticut | |
| Cook Children's Medical Center Fort Worth, Texas | Site Public Contact - (CookChildrensResearch@cookchildrens.org) |
| Corewell Health Children's Royal Oak, Michigan | |
| Corewell Health Grand Rapids Hospitals - Butterworth Hospital Grand Rapids, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
| Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital Grand Rapids, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
| Dana-Farber Cancer Institute Boston, Massachusetts | |
| Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center Lebanon, New Hampshire | Site Public Contact - (cancer.research.nurse@dartmouth.edu) |
| Dayton Children's Hospital Dayton, Ohio | |
| Dell Children's Medical Center of Central Texas Austin, Texas | Site Public Contact - (TXAUS-DL-SFCHemonc.research@ascension.org) |
| Driscoll Children's Hospital Corpus Christi, Texas | Site Public Contact - (Crystal.DeLosSantos@dchstx.org) |
| Duke University Medical Center Durham, North Carolina | |
| East Carolina University Greenville, North Carolina | Site Public Contact - (eubankss@ecu.edu) |
| East Tennessee Childrens Hospital Knoxville, Tennessee | |
| Eastern Maine Medical Center Bangor, Maine | |
| El Paso Children's Hospital El Paso, Texas | Site Public Contact - (ranjan.bista@ttuhsc.edu) |
| Geisinger Medical Center Danville, Pennsylvania | Site Public Contact - (cancerresearch@geisinger.edu) |
| Golisano Children's Hospital of Southwest Florida Fort Myers, Florida | Site Public Contact - (molly.arnstrom@leehealth.org) |
| Hackensack University Medical Center Hackensack, New Jersey | |
| Hospital for Sick Children Toronto, Ontario | Site Public Contact - (ask.CRS@sickkids.ca) |
| IWK Health Centre Halifax, Nova Scotia | Site Public Contact - (Research@iwk.nshealth.ca) |
| Johns Hopkins All Children's Hospital St. Petersburg, Florida | Site Public Contact - (Ashley.Repp@jhmi.edu) |
| Johns Hopkins University/Sidney Kimmel Cancer Center Baltimore, Maryland | Site Public Contact - (jhcccro@jhmi.edu) |
| Kaiser Permanente Downey Medical Center Downey, California | |
| Kaiser Permanente Los Angeles Medical Center Los Angeles, California | Site Public Contact - (clinical.trials@kp.org) |
| Kaiser Permanente-Oakland Oakland, California | Site Public Contact - (Kpoct@kp.org) |
| Kapiolani Medical Center for Women and Children Honolulu, Hawaii | |
| Laura and Isaac Perlmutter Cancer Center at NYU Langone New York, New York | Site Public Contact - (CancerTrials@nyulangone.org) |
| Legacy Emanuel Children's Hospital Portland, Oregon | |
| Lehigh Valley Hospital-Cedar Crest Allentown, Pennsylvania | Site Public Contact - (Morgan_M.Horton@lvhn.org) |
| Loma Linda University Medical Center Loma Linda, California | |
| Loyola University Medical Center Maywood, Illinois | |
| Lucile Packard Children's Hospital Stanford University Palo Alto, California | Site Public Contact - (ccto-office@stanford.edu) |
| Lurie Children's Hospital-Chicago Chicago, Illinois | |
| Madigan Army Medical Center Tacoma, Washington | Site Public Contact - (melissa.a.forouhar.mil@health.mil) |
| Maimonides Medical Center Brooklyn, New York | |
| Maine Children's Cancer Program Scarborough, Maine | Site Public Contact - (clinicalresearch@mainehealth.org) |
| Marshfield Medical Center-Marshfield Marshfield, Wisconsin | |
| Mary Bridge Children's Hospital and Health Center Tacoma, Washington | Site Public Contact - (research@multicare.org) |
| Massachusetts General Hospital Cancer Center Boston, Massachusetts | |
| Mayo Clinic in Rochester Rochester, Minnesota | |
| McMaster Children's Hospital at Hamilton Health Sciences Hamilton, Ontario | |
| Medical City Dallas Hospital Dallas, Texas | |
| Medical University of South Carolina Charleston, South Carolina | Site Public Contact - (hcc-clinical-trials@musc.edu) |
| Memorial Sloan Kettering Cancer Center New York, New York | |
| Mercy Hospital Saint Louis St Louis, Missouri | |
| Methodist Children's Hospital of South Texas San Antonio, Texas | Site Public Contact - (Vinod.GidvaniDiaz@hcahealthcare.com) |
| Michigan State University East Lansing, Michigan | |
| Miller Children's and Women's Hospital Long Beach Long Beach, California | |
| Montefiore Medical Center - Moses Campus The Bronx, New York | Site Public Contact - (eskwak@montefiore.org) |
| Montefiore Medical Center-Einstein Campus The Bronx, New York | Site Public Contact - (eskwak@montefiore.org) |
| Morristown Medical Center Morristown, New Jersey | |
| Nationwide Children's Hospital Columbus, Ohio | Site Public Contact - (Melinda.Triplet@nationwidechildrens.org) |
| Nemours Children's Clinic - Pensacola Pensacola, Florida | Site Public Contact - (helpdesk@childrensoncologygroup.org) |
| Nemours Children's Clinic-Jacksonville Jacksonville, Florida | Site Public Contact - (Allison.bruce@nemours.org) |
| Nemours Children's Hospital Orlando, Florida | Site Public Contact - (Allison.bruce@nemours.org) |
| New York Medical College Valhalla, New York | |
| Newark Beth Israel Medical Center Newark, New Jersey | Site Public Contact - (Christine.Kosmides@rwjbh.org) |
| Nicklaus Children's Hospital Miami, Florida | |
| Norton Children's Hospital Louisville, Kentucky | Site Public Contact - (CancerResource@nortonhealthcare.org) |
| OSF Children's Hospital of Illinois Peoria, Illinois | Site Public Contact - (ChildrensHospitalofIllinois@osfhealthcare.org) |
| Ochsner Medical Center Jefferson New Orleans, Louisiana | Site Public Contact - (Elisemarie.curry@ochsner.org) |
| Oncology Las Vegas - Henderson Henderson, Nevada | |
| Oregon Health and Science University Portland, Oregon | Site Public Contact - (trials@ohsu.edu) |
| Penn State Children's Hospital Hershey, Pennsylvania | |
| Perth Children's Hospital Perth, Western Australia | Site Public Contact - (helpdesk@childrensoncologygroup.org) |
| Phoenix Childrens Hospital Phoenix, Arizona | |
| Primary Children's Hospital Salt Lake City, Utah | |
| Prisma Health Cancer Institute - Faris Greenville, South Carolina | Site Public Contact - (Kim.Williams3@prismahealth.org) |
| Prisma Health Richland Hospital Columbia, South Carolina | Site Public Contact - (Kim.Williams3@prismahealth.org) |
| ProMedica Flower Hospital Sylvania, Ohio | Site Public Contact - (PCIOncResearch@promedica.org) |
| ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital Toledo, Ohio | Site Public Contact - (PCIOncResearch@promedica.org) |
| Providence Alaska Medical Center Anchorage, Alaska | Site Public Contact - (AKPAMC.OncologyResearchSupport@providence.org) |
| Providence Sacred Heart Medical Center and Children's Hospital Spokane, Washington | Site Public Contact - (HopeBeginsHere@providence.org) |
| Queensland Children's Hospital South Brisbane, Queensland | |
| Rady Children's Hospital - San Diego San Diego, California | |
| Rainbow Babies and Childrens Hospital Cleveland, Ohio | |
| Renown Regional Medical Center Reno, Nevada | Site Public Contact - (Renown-CRD@renown.org) |
| Rhode Island Hospital Providence, Rhode Island | |
| Riley Hospital for Children Indianapolis, Indiana | Sandeep Batra - (batras@iu.edu) |
| Roswell Park Cancer Institute Buffalo, New York | Site Public Contact - (askroswell@roswellpark.org) |
| Royal Children's Hospital Parkville, Victoria | Site Public Contact - (Jordan.Hansford@rch.org.au) |
| Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital New Brunswick, New Jersey | |
| Sacred Heart Hospital Pensacola, Florida | |
| Saint Christopher's Hospital for Children Philadelphia, Pennsylvania | |
| Saint Joseph's Hospital/Children's Hospital-Tampa Tampa, Florida | Site Public Contact - (jennifer.manns@baycare.org) |
| Saint Joseph's Regional Medical Center Paterson, New Jersey | Site Public Contact - (HallL@sjhmc.org) |
| Saint Jude Children's Research Hospital Memphis, Tennessee | Site Public Contact - (referralinfo@stjude.org) |
| Saint Luke's Cancer Institute - Boise Boise, Idaho | Site Public Contact - (eslinget@slhs.org) |
| Saint Peter's University Hospital New Brunswick, New Jersey | Site Public Contact - (kcovert@saintpetersuh.com) |
| Sanford Broadway Medical Center Fargo, North Dakota | Site Public Contact - (OncologyClinicalTrialsFargo@sanfordhealth.org) |
| Sanford USD Medical Center - Sioux Falls Sioux Falls, South Dakota | Site Public Contact - (OncologyClinicalTrialsSF@SanfordHealth.org) |
| Scott and White Memorial Hospital Temple, Texas | |
| Seattle Children's Hospital Seattle, Washington | |
| Sinai Hospital of Baltimore Baltimore, Maryland | |
| Smilow Cancer Center/Yale-New Haven Hospital New Haven, Connecticut | Site Public Contact - (canceranswers@yale.edu) |
| State University of New York Upstate Medical University Syracuse, New York | |
| Stony Brook University Medical Center Stony Brook, New York | |
| Sydney Children's Hospital Randwick, New South Wales | |
| The Children's Hospital at TriStar Centennial Nashville, Tennessee | |
| The Children's Hospital at Westmead Westmead, New South Wales | |
| The Montreal Children's Hospital of the MUHC Montreal, Quebec | Site Public Contact - (info@thechildren.com) |
| The Steven and Alexandra Cohen Children's Medical Center of New York New Hyde Park, New York | |
| UCSF Medical Center-Mission Bay San Francisco, California | Site Public Contact - (cancertrials@ucsf.edu) |
| UF Health Cancer Institute - Gainesville Gainesville, Florida | Site Public Contact - (cancer-center@ufl.edu) |
| UT MD Anderson Cancer Center Houston, Texas | Najat C. Daw - (ndaw@mdanderson.org) |
| UT Southwestern/Simmons Cancer Center-Dallas Dallas, Texas | Daniel C. Bowers - (Daniel.Bowers@utsouthwestern.edu) |
| University of Alberta Hospital Edmonton, Alberta | Site Public Contact - (pedsoncologyresearch@ahs.ca) |
| University of Arizona Cancer Center-North Campus Tucson, Arizona | |
| University of Chicago Comprehensive Cancer Center Chicago, Illinois | Site Public Contact - (cancerclinicaltrials@bsd.uchicago.edu) |
| University of Illinois Chicago, Illinois | |
| University of Iowa/Holden Comprehensive Cancer Center Iowa City, Iowa | |
| University of Kentucky/Markey Cancer Center Lexington, Kentucky | |
| University of Miami Miller School of Medicine-Sylvester Cancer Center Miami, Florida | |
| University of Mississippi Medical Center Jackson, Mississippi | |
| University of Missouri Children's Hospital Columbia, Missouri | Site Public Contact - (snwq62@health.missouri.edu) |
| University of Nebraska Medical Center Omaha, Nebraska | Site Public Contact - (unmcrsa@unmc.edu) |
| University of Oklahoma Health Sciences Center Oklahoma City, Oklahoma | Site Public Contact - (ou-clinical-trials@ouhsc.edu) |
| University of Rochester Rochester, New York | |
| University of Texas Health Science Center at San Antonio San Antonio, Texas | Site Public Contact - (phoresearchoffice@uthscsa.edu) |
| University of Vermont and State Agricultural College Burlington, Vermont | Site Public Contact - (rpo@uvm.edu) |
| University of Virginia Cancer Center Charlottesville, Virginia | Site Public Contact - (uvacancertrials@hscmail.mcc.virginia.edu) |
| University of Wisconsin Carbone Cancer Center - Eastpark Medical Center Madison, Wisconsin | Site Public Contact - (clinicaltrials@cancer.wisc.edu) |
| University of Wisconsin Carbone Cancer Center - University Hospital Madison, Wisconsin | Site Public Contact - (clinicaltrials@cancer.wisc.edu) |
| VCU Massey Comprehensive Cancer Center Richmond, Virginia | |
| Valley Children's Hospital Madera, California | Site Public Contact - (Research@valleychildrens.org) |
| Vanderbilt University/Ingram Cancer Center Nashville, Tennessee | |
| Wake Forest University Health Sciences Winston-Salem, North Carolina | |
| Washington University School of Medicine St Louis, Missouri | Site Public Contact - (info@siteman.wustl.edu) |
| West Virginia University Healthcare Morgantown, West Virginia | Site Public Contact - (cancertrialsinfo@hsc.wvu.edu) |
| Women's and Children's Hospital-Adelaide North Adelaide, South Australia | Site Public Contact - (cywhs.oncsec@health.sa.gov.au) |
| Yale University New Haven, Connecticut | Site Public Contact - (canceranswers@yale.edu) |
The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study
ctrrecruit@vcu.edu
NCT04726241
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Inclusion Criteria:
* Patients must be less than 22 years of age at the time of study enrollment
* Patient must have one of the following at the time of study enrollment:
* Patient has known or suspected relapsed/refractory (including primary refractory) AML as defined in protocol
* This includes isolated myeloid sarcoma
* Patient has known or suspected relapsed/refractory (including primary refractory) myeloid leukemia of Down syndrome (ML-DS)
* Patient has known or suspected relapsed ALL as defined in protocol that meets one of the following criteria:
* Second or greater B-ALL medullary relapse, excluding KMT2Ar
* Any first or greater B-ALL medullary relapse involving KMT2Ar
* Any first or greater T-ALL medullary relapse with or without KMT2Ar
* Patient has known or suspected relapsed/refractory (including primary refractory) mixed phenotype acute leukemia (MPAL) as defined in protocol
* Patient has known or suspected de novo or relapsed/refractory (including primary refractory) treatment-related AML (t-AML)
* Patient has known or suspected de novo or relapsed/refractory (including primary refractory) myelodysplastic syndrome (MDS) or treatment-related myelodysplastic syndrome (t-MDS)
* Note: Relapsed/refractory disease includes stable disease, progressive disease, and disease relapse.
* Patient has known or suspected de novo or relapsed/refractory (including primary refractory) juvenile myelomonocytic leukemia (JMML)
* Note: Relapsed/refractory disease includes stable disease, progressive disease, and disease relapse.
* All patients and/or their parents or legal guardians must sign a written informed consent
* All institutional, Food and Drug Administration (FDA), and National Cancer Institute (NCI) requirements for human studies must be met PROCEDURE: Biospecimen Collection
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Acute Myeloid Leukemia Post Cytotoxic Therapy, Juvenile Myelomonocytic Leukemia, Mixed Phenotype Acute Leukemia, Myelodysplastic Syndrome, Myelodysplastic Syndrome Post Cytotoxic Therapy, Myeloid Leukemia Associated With Down Syndrome
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See this study on ClinicalTrials.gov
Show 184 locations
Study Locations
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| Location | Contacts |
|---|---|
| Advocate Children's Hospital-Oak Lawn Oak Lawn, Illinois | |
| Advocate Children's Hospital-Park Ridge Park Ridge, Illinois | Site Public Contact - (helpdesk@childrensoncologygroup.org) |
| Albany Medical Center Albany, New York | |
| Alberta Children's Hospital Calgary, Alberta | Site Public Contact - (research4kids@ucalgary.ca) |
| Alfred I duPont Hospital for Children Wilmington, Delaware | Site Public Contact - (Allison.bruce@nemours.org) |
| Alliance for Childhood Diseases/Cure 4 the Kids Foundation Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Arkansas Children's Hospital Little Rock, Arkansas | |
| Arnold Palmer Hospital for Children Orlando, Florida | Site Public Contact - (Jennifer.spinelli@orlandohealth.com) |
| Ascension Saint Vincent Indianapolis Hospital Indianapolis, Indiana | Site Public Contact - (research@stvincent.org) |
| BI-LO Charities Children's Cancer Center Greenville, South Carolina | Site Public Contact - (Kim.Williams3@prismahealth.org) |
| Banner Children's at Desert Mesa, Arizona | |
| Banner University Medical Center - Tucson Tucson, Arizona | Site Public Contact - (UACC-IIT@uacc.arizona.edu) |
| Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center Houston, Texas | Site Public Contact - (burton@bcm.edu) |
| Blank Children's Hospital Des Moines, Iowa | Site Public Contact - (samantha.mallory@unitypoint.org) |
| British Columbia Children's Hospital Vancouver, British Columbia | |
| Bronson Methodist Hospital Kalamazoo, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
| Broward Health Medical Center Fort Lauderdale, Florida | Site Public Contact - (Allison.bruce@nemours.org) |
| C S Mott Children's Hospital Ann Arbor, Michigan | |
| CHU de Quebec-Centre Hospitalier de l'Universite Laval (CHUL) Québec, | Site Public Contact - (rechclinique@crchudequebec.ulaval.ca) |
| CancerCare Manitoba Winnipeg, Manitoba | Site Public Contact - (ctu_web@cancercare.mb.ca) |
| Cardinal Glennon Children's Medical Center St Louis, Missouri | |
| Carilion Children's Roanoke, Virginia | Site Public Contact - (wpmccarty@carilionclinic.org) |
| Carolinas Medical Center/Levine Cancer Institute Charlotte, North Carolina | |
| Centre Hospitalier Universitaire Sainte-Justine Montreal, Quebec | Site Public Contact - (yvan.samson@umontreal.ca) |
| Centre Hospitalier Universitaire de Sherbrooke-Fleurimont Sherbrooke, Quebec | Site Public Contact - (crcinformation.chus@ssss.gouv.qc.ca) |
| Children's Healthcare of Atlanta - Arthur M Blank Hospital Atlanta, Georgia | Site Public Contact - (Olivia.Floyd@choa.org) |
| Children's Hospital London, Ontario | |
| Children's Hospital Colorado Aurora, Colorado | Site Public Contact - (josh.b.gordon@nsmtp.kp.org) |
| Children's Hospital Los Angeles Los Angeles, California | |
| Children's Hospital Medical Center Of Akron Akron, Ohio | |
| Children's Hospital New Orleans New Orleans, Louisiana | |
| Children's Hospital Of Eastern Ontario Ottawa, Ontario | |
| Children's Hospital and Medical Center of Omaha Omaha, Nebraska | |
| Children's Hospital of Alabama Birmingham, Alabama | Site Public Contact - (oncologyresearch@peds.uab.edu) |
| Children's Hospital of Michigan Detroit, Michigan | Site Public Contact - (helpdesk@childrensoncologygroup.org) |
| Children's Hospital of Orange County Orange, California | Site Public Contact - (oncresearch@choc.org) |
| Children's Hospital of Philadelphia Philadelphia, Pennsylvania | Site Public Contact - (CancerTrials@email.chop.edu) |
| Children's Hospital of Pittsburgh of UPMC Pittsburgh, Pennsylvania | Site Public Contact - (jean.tersak@chp.edu) |
| Children's Hospital of San Antonio San Antonio, Texas | Site Public Contact - (bridget.medina@christushealth.org) |
| Children's Hospital of the King's Daughters Norfolk, Virginia | Site Public Contact - (CCBDCresearch@chkd.org) |
| Children's Hospitals and Clinics of Minnesota - Minneapolis Minneapolis, Minnesota | Site Public Contact - (pauline.mitby@childrensmn.org) |
| Children's Mercy Hospitals and Clinics Kansas City, Missouri | Site Public Contact - (COGResearchGroup@cmh.edu) |
| Children's National Medical Center Washington D.C., District of Columbia | Site Public Contact - (OncCRC_OnCall@childrensnational.org) |
| Christchurch Hospital Christchurch, | |
| Cincinnati Children's Hospital Medical Center Cincinnati, Ohio | Site Public Contact - (cancer@cchmc.org) |
| Cleveland Clinic Foundation Cleveland, Ohio | |
| Connecticut Children's Medical Center Hartford, Connecticut | |
| Cook Children's Medical Center Fort Worth, Texas | Site Public Contact - (CookChildrensResearch@cookchildrens.org) |
| Corewell Health Children's Royal Oak, Michigan | |
| Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital Grand Rapids, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
| Covenant Children's Hospital Lubbock, Texas | Site Public Contact - (mbisbee@providence.org) |
| Dana-Farber Cancer Institute Boston, Massachusetts | |
| Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center Lebanon, New Hampshire | Site Public Contact - (cancer.research.nurse@dartmouth.edu) |
| Dayton Children's Hospital Dayton, Ohio | |
| Dell Children's Medical Center of Central Texas Austin, Texas | Site Public Contact - (TXAUS-DL-SFCHemonc.research@ascension.org) |
| Driscoll Children's Hospital Corpus Christi, Texas | Site Public Contact - (Crystal.DeLosSantos@dchstx.org) |
| Duke University Medical Center Durham, North Carolina | |
| East Carolina University Greenville, North Carolina | Site Public Contact - (eubankss@ecu.edu) |
| East Tennessee Childrens Hospital Knoxville, Tennessee | |
| Eastern Maine Medical Center Bangor, Maine | |
| El Paso Children's Hospital El Paso, Texas | Site Public Contact - (ranjan.bista@ttuhsc.edu) |
| Geisinger Medical Center Danville, Pennsylvania | Site Public Contact - (cancerresearch@geisinger.edu) |
| Golisano Children's Hospital of Southwest Florida Fort Myers, Florida | Site Public Contact - (molly.arnstrom@leehealth.org) |
| HIMA San Pablo Oncologic Hospital Caguas, | |
| Hackensack University Medical Center Hackensack, New Jersey | |
| Hospital for Sick Children Toronto, Ontario | Site Public Contact - (ask.CRS@sickkids.ca) |
| IWK Health Centre Halifax, Nova Scotia | Site Public Contact - (Research@iwk.nshealth.ca) |
| Inova Fairfax Hospital Falls Church, Virginia | Site Public Contact - (Stephanie.VanBebber@inova.org) |
| Jersey Shore Medical Center Neptune City, New Jersey | |
| Johns Hopkins All Children's Hospital St. Petersburg, Florida | Site Public Contact - (Ashley.Repp@jhmi.edu) |
| Johns Hopkins University/Sidney Kimmel Cancer Center Baltimore, Maryland | Site Public Contact - (jhcccro@jhmi.edu) |
| Kaiser Permanente Downey Medical Center Downey, California | |
| Kaiser Permanente-Oakland Oakland, California | Site Public Contact - (Kpoct@kp.org) |
| Kapiolani Medical Center for Women and Children Honolulu, Hawaii | |
| Laura and Isaac Perlmutter Cancer Center at NYU Langone New York, New York | |
| Legacy Emanuel Children's Hospital Portland, Oregon | |
| Lehigh Valley Hospital-Cedar Crest Allentown, Pennsylvania | Site Public Contact - (Morgan_M.Horton@lvhn.org) |
| Loma Linda University Medical Center Loma Linda, California | |
| Loyola University Medical Center Maywood, Illinois | |
| Lucile Packard Children's Hospital Stanford University Palo Alto, California | Site Public Contact - (ccto-office@stanford.edu) |
| Lurie Children's Hospital-Chicago Chicago, Illinois | |
| Madigan Army Medical Center Tacoma, Washington | Site Public Contact - (melissa.a.forouhar.mil@health.mil) |
| Maimonides Medical Center Brooklyn, New York | |
| Maine Children's Cancer Program Scarborough, Maine | Site Public Contact - (clinicalresearch@mainehealth.org) |
| Marshfield Medical Center-Marshfield Marshfield, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Mary Bridge Children's Hospital and Health Center Tacoma, Washington | Site Public Contact - (research@multicare.org) |
| Mayo Clinic in Rochester Rochester, Minnesota | |
| MedStar Georgetown University Hospital Washington D.C., District of Columbia | |
| Medical City Dallas Hospital Dallas, Texas | |
| Medical University of South Carolina Charleston, South Carolina | Site Public Contact - (hcc-clinical-trials@musc.edu) |
| Memorial Health University Medical Center Savannah, Georgia | Site Public Contact - (Lorraine.OHara@hcahealthcare.com) |
| Memorial Regional Hospital/Joe DiMaggio Children's Hospital Hollywood, Florida | Site Public Contact - (OHR@mhs.net) |
| Memorial Sloan Kettering Cancer Center New York, New York | |
| Mercy Hospital Saint Louis St Louis, Missouri | |
| Methodist Children's Hospital of South Texas San Antonio, Texas | Site Public Contact - (Vinod.GidvaniDiaz@hcahealthcare.com) |
| Michigan State University East Lansing, Michigan | |
| Miller Children's and Women's Hospital Long Beach Long Beach, California | |
| Mission Hospital Asheville, North Carolina | Site Public Contact - (NCDV.ResearchRegulatory@HCAHealthcare.com) |
| Montefiore Medical Center - Moses Campus The Bronx, New York | Site Public Contact - (eskwak@montefiore.org) |
| Morristown Medical Center Morristown, New Jersey | |
| NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center New York, New York | Site Public Contact - (cancerclinicaltrials@cumc.columbia.edu) |
| NYU Langone Hospital - Long Island Mineola, New York | Site Public Contact - (cancertrials@nyulangone.org) |
| Nationwide Children's Hospital Columbus, Ohio | Site Public Contact - (Melinda.Triplet@nationwidechildrens.org) |
| Nemours Children's Clinic - Pensacola Pensacola, Florida | Site Public Contact - (helpdesk@childrensoncologygroup.org) |
| Nemours Children's Clinic-Jacksonville Jacksonville, Florida | Site Public Contact - (Allison.bruce@nemours.org) |
| Nemours Children's Hospital Orlando, Florida | Site Public Contact - (Allison.bruce@nemours.org) |
| New York Medical College Valhalla, New York | |
| Nicklaus Children's Hospital Miami, Florida | |
| Northwestern Medicine Central DuPage Hospital Winfield, Illinois | Site Public Contact - (Claudine.Gamster@CadenceHealth.org) |
| Norton Children's Hospital Louisville, Kentucky | Site Public Contact - (CancerResource@nortonhealthcare.org) |
| Novant Health Presbyterian Medical Center Charlotte, North Carolina | Site Public Contact - (kashah@novanthealth.org) |
| OSF Children's Hospital of Illinois Peoria, Illinois | Site Public Contact - (ChildrensHospitalofIllinois@osfhealthcare.org) |
| Ochsner Medical Center Jefferson New Orleans, Louisiana | Site Public Contact - (Elisemarie.curry@ochsner.org) |
| Oregon Health and Science University Portland, Oregon | Site Public Contact - (trials@ohsu.edu) |
| Penn State Children's Hospital Hershey, Pennsylvania | |
| Perth Children's Hospital Perth, Western Australia | Site Public Contact - (helpdesk@childrensoncologygroup.org) |
| Phoenix Childrens Hospital Phoenix, Arizona | |
| Primary Children's Hospital Salt Lake City, Utah | |
| Prisma Health Richland Hospital Columbia, South Carolina | Site Public Contact - (Kim.Williams3@prismahealth.org) |
| ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital Toledo, Ohio | Site Public Contact - (PCIOncResearch@promedica.org) |
| Providence Alaska Medical Center Anchorage, Alaska | Site Public Contact - (AKPAMC.OncologyResearchSupport@providence.org) |
| Providence Sacred Heart Medical Center and Children's Hospital Spokane, Washington | Site Public Contact - (HopeBeginsHere@providence.org) |
| Queensland Children's Hospital South Brisbane, Queensland | |
| Rady Children's Hospital - San Diego San Diego, California | |
| Rainbow Babies and Childrens Hospital Cleveland, Ohio | |
| Renown Regional Medical Center Reno, Nevada | Site Public Contact - (Renown-CRD@renown.org) |
| Rhode Island Hospital Providence, Rhode Island | |
| Riley Hospital for Children Indianapolis, Indiana | |
| Rocky Mountain Hospital for Children-Presbyterian Saint Luke's Medical Center Denver, Colorado | Site Public Contact - (PSGResearchSharedMailbox@HCAHealthcare.com) |
| Royal Children's Hospital Parkville, Victoria | Site Public Contact - (Jordan.Hansford@rch.org.au) |
| Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital New Brunswick, New Jersey | |
| Sacred Heart Hospital Pensacola, Florida | |
| Saint Christopher's Hospital for Children Philadelphia, Pennsylvania | |
| Saint Joseph's Hospital/Children's Hospital-Tampa Tampa, Florida | Site Public Contact - (jennifer.manns@baycare.org) |
| Saint Joseph's Regional Medical Center Paterson, New Jersey | Site Public Contact - (HallL@sjhmc.org) |
| Saint Jude Children's Research Hospital Memphis, Tennessee | Site Public Contact - (referralinfo@stjude.org) |
| Saint Luke's Cancer Institute - Boise Boise, Idaho | Site Public Contact - (eslinget@slhs.org) |
| Saint Mary's Medical Center West Palm Beach, Florida | |
| Saint Peter's University Hospital New Brunswick, New Jersey | Site Public Contact - (kcovert@saintpetersuh.com) |
| Sanford Broadway Medical Center Fargo, North Dakota | Site Public Contact - (OncologyClinicalTrialsFargo@sanfordhealth.org) |
| Sanford USD Medical Center - Sioux Falls Sioux Falls, South Dakota | Site Public Contact - (OncologyClinicalTrialsSF@SanfordHealth.org) |
| Seattle Children's Hospital Seattle, Washington | |
| Sinai Hospital of Baltimore Baltimore, Maryland | |
| Southern Illinois University School of Medicine Springfield, Illinois | |
| Starship Children's Hospital Grafton, Auckland | |
| State University of New York Upstate Medical University Syracuse, New York | |
| Stony Brook University Medical Center Stony Brook, New York | |
| Summerlin Hospital Medical Center Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| The Children's Hospital at TriStar Centennial Nashville, Tennessee | |
| The Children's Hospital at Westmead Westmead, New South Wales | |
| The Montreal Children's Hospital of the MUHC Montreal, Quebec | Site Public Contact - (info@thechildren.com) |
| The Steven and Alexandra Cohen Children's Medical Center of New York New Hyde Park, New York | |
| UCSF Benioff Children's Hospital Oakland Oakland, California | Site Public Contact - (PedOncRschOAK@ucsf.edu) |
| UCSF Medical Center-Mission Bay San Francisco, California | Site Public Contact - (cancertrials@ucsf.edu) |
| UF Health Cancer Institute - Gainesville Gainesville, Florida | |
| UMC Cancer Center / UMC Health System Lubbock, Texas | |
| UNC Lineberger Comprehensive Cancer Center Chapel Hill, North Carolina | Site Public Contact - (cancerclinicaltrials@med.unc.edu) |
| USA Health Strada Patient Care Center Mobile, Alabama | |
| UT MD Anderson Cancer Center Houston, Texas | Site Public Contact - (askmdanderson@mdanderson.org) |
| UT Southwestern/Simmons Cancer Center-Dallas Dallas, Texas | Site Public Contact - (canceranswerline@UTSouthwestern.edu) |
| University Pediatric Hospital San Juan, | |
| University of Alberta Hospital Edmonton, Alberta | Site Public Contact - (pedsoncologyresearch@ahs.ca) |
| University of Chicago Comprehensive Cancer Center Chicago, Illinois | Site Public Contact - (cancerclinicaltrials@bsd.uchicago.edu) |
| University of Illinois Chicago, Illinois | |
| University of Iowa/Holden Comprehensive Cancer Center Iowa City, Iowa | |
| University of Kentucky/Markey Cancer Center Lexington, Kentucky | |
| University of Minnesota/Masonic Cancer Center Minneapolis, Minnesota | |
| University of Mississippi Medical Center Jackson, Mississippi | |
| University of Missouri Children's Hospital Columbia, Missouri | Site Public Contact - (snwq62@health.missouri.edu) |
| University of Nebraska Medical Center Omaha, Nebraska | Site Public Contact - (unmcrsa@unmc.edu) |
| University of New Mexico Cancer Center Albuquerque, New Mexico | Site Public Contact - (HSC-ClinicalTrialInfo@salud.unm.edu) |
| University of Oklahoma Health Sciences Center Oklahoma City, Oklahoma | Site Public Contact - (ou-clinical-trials@ouhsc.edu) |
| University of Rochester Rochester, New York | |
| University of Texas Health Science Center at San Antonio San Antonio, Texas | Site Public Contact - (phoresearchoffice@uthscsa.edu) |
| University of Virginia Cancer Center Charlottesville, Virginia | Site Public Contact - (uvacancertrials@hscmail.mcc.virginia.edu) |
| University of Wisconsin Carbone Cancer Center - University Hospital Madison, Wisconsin | Kenneth B. De Santes - (kbdesantes@pediatrics.wisc.edu) |
| VCU Massey Comprehensive Cancer Center Richmond, Virginia | Site Public Contact - (CTOclinops@vcu.edu) |
| Valley Children's Hospital Madera, California | Site Public Contact - (Research@valleychildrens.org) |
| Vanderbilt University/Ingram Cancer Center Nashville, Tennessee | |
| Wake Forest University Health Sciences Winston-Salem, North Carolina | |
| Walter Reed National Military Medical Center Bethesda, Maryland | |
| Washington University School of Medicine St Louis, Missouri | Site Public Contact - (info@siteman.wustl.edu) |
| West Virginia University Healthcare Morgantown, West Virginia | Site Public Contact - (cancertrialsinfo@hsc.wvu.edu) |
| Yale University New Haven, Connecticut | Site Public Contact - (canceranswers@yale.edu) |
Anticoagulation in ICH Survivors for Stroke Prevention and Recovery (ASPIRE)
Kevin N Sheth, MD - kevin.sheth@yale.edu
NCT03907046
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Inclusion Criteria:
* Age at least 18 years
* Intracerebral hemorrhage (ICH) (including primary intraventricular hemorrhage) confirmed by brain CT or MRI
* Can be randomized within 14-180 days after ICH onset
* Non-valvular AF (defined as atrial fibrillation or atrial flutter), documented by electrocardiography or a physician-confirmed history of prior AF
* Provision of signed and dated informed consent form by patient or legally authorized representative
* For females of reproductive potential: use of highly effective contraception
Exclusion Criteria:
* Index event is hemorrhagic transformation of a brain infarction or hemorrhage into a tumor
* History of earlier ICH within 12 months preceding index event
* Active infective endocarditis
* Clear indication for anticoagulant drugs (e.g., requires anticoagulation for deep vein thrombosis or pulmonary embolism) or antiplatelet drugs (e.g., requires aspirin or clopidogrel for recent coronary stent).
* Previous or planned left atrial appendage closure
* Clinically significant bleeding diathesis
* Serum creatinine ≥2.5 mg/dL
* Active hepatitis or hepatic insufficiency with Child-Pugh score B or C
* Anemia (hemoglobin \<8 g/dL) or thrombocytopenia (\<100 x 10\^9/L) that is chronic in the judgment of the investigator
* Pregnant or breastfeeding
* Known allergy to aspirin or apixaban
* Concomitant participation in a competing trial
* Considered by the investigator to have a condition that precludes safe or active participation in the trial
* Persistent, uncontrolled systolic blood pressure (≥180 mm Hg)
* ICH caused by an arteriovenous malformation (AVM) that has not yet been secured DRUG: Apixaban, DRUG: Aspirin
Intracerebral Hemorrhage, Atrial Fibrillation
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Show 187 locations
Study Locations
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| Location | Contacts |
|---|---|
| Abbott Northwestern Hospital Minneapolis, Minnesota | |
| Albany Medical Center Albany, New York | |
| Arrowhead Regional Medical Center Colton, California | |
| Ascension Sacred Heart Pensacola Pensacola, Florida | |
| Ascension St. John Medical Center Tulsa, Oklahoma | |
| Augusta University Medical Center Augusta, Georgia | |
| Avera Research Institute Sioux Falls, South Dakota | |
| Banner University Medical Center Phoenix, Arizona | |
| Baptist Health Lexington Lexington, Kentucky | |
| Barnes Jewish Hospital St Louis, Missouri | |
| Baylor College of Medicine Medical Center Houston, Texas | |
| Baystate Medical Center Springfield, Massachusetts | |
| Beth Israel Deaconess Medical Center Boston, Massachusetts | |
| Bon Secours St. Mary's Hospital Richmond, Virginia | |
| Boston Medical Center Boston, Massachusetts | |
| Broward Health Medical Center Fort Lauderdale, Florida | |
| Buffalo General Medical Center Buffalo, New York | |
| Burke Rehabilitation Center White Plains, New York | |
| Capital Health Regional Medical Center Pennington, New Jersey | |
| Carolinas Medical Center Charlotte, North Carolina | |
| Cedars-Sinai Medical Center Los Angeles, California | |
| Central DuPage Hospital Winfield, Illinois | |
| Chandler Regional Medical Center Chandler, Arizona | |
| Cleveland Clinic Cleveland, Ohio | |
| Cleveland Clinic Akron General Akron, Ohio | |
| Cleveland Clinic Tradition Hospital Port Saint Lucie, Florida | |
| Community Regional Medical Center of Fresno Fresno, California | |
| Cooperman Barnabas Medical Center Livingston, New Jersey | |
| Cox Medical Center South Springfield, Missouri | |
| Danbury Hospital Danbury, Connecticut | |
| Desert Regional Medical Center Palm Springs, California | |
| Doctors Medical Center Modesto, Modesto, CA Modesto, California | |
| Duke University Hospital Durham, North Carolina | |
| ECU Health Medical Center Greenville, North Carolina | |
| Eastern Maine Medical Center Bangor, Maine | |
| Eden Medical Center, Castro Valley Castro Valley, California | |
| Emory University Hospital Atlanta, Georgia | |
| Erlanger Health System Chattanooga, Tennessee | |
| Evanston Hospital Evanston, Illinois | |
| Forsyth Medical Center Winston-Salem, North Carolina | |
| Fort Sanders Regional Medical Center Knoxville, Tennessee | |
| Froedtert Hospital Milwaukee, Wisconsin | |
| Geisinger Medical Center Danville, Pennsylvania | |
| George Washington University Hospital Washington D.C., District of Columbia | |
| Good Samaritan Hospital Corvallis, Oregon | |
| Grady Memorial Hospital Delaware, Ohio | |
| Greenville Hospital System Greenville, South Carolina | |
| Hackensack University Medical Center Hackensack, New Jersey | |
| Harborview Medical Center Seattle, Washington | |
| Hartford Hospital Hartford, Connecticut | |
| HealthPartners Methodist Hospital Saint Louis Park, Minnesota | |
| Henry Ford Hospital Detroit, Michigan | |
| Hoag Hospital Newport Beach Newport Beach, California | |
| Hospital of the University of Pennsylvania Philadelphia, Pennsylvania | |
| Houston Methodist Hospital Houston, Texas | |
| Huntington Memorial Hospital Pasadena, California | |
| IU Health Methodist Hospital Indianapolis, Indiana | |
| Inova Fairfax Hospital Falls Church, Virginia | |
| J.W. Ruby Memorial Hospital Morgantown, West Virginia | |
| JFK Medical Center Edison, New Jersey | |
| Jackson Memorial Hospital Miami, Florida | |
| Javon Bea Hospital - Riverside Rockford, Illinois | |
| Jefferson Abington Hospital Abington, Pennsylvania | |
| Jersey Shore University Medical Center Neptune City, New Jersey | |
| Kaiser Permanente Fontana Medical Center Fontana, California | |
| Kaiser Permanente Los Angeles Medical Center Los Angeles, California | |
| Kaiser Permanente Redwood City Medical Center, Redwood City, CA Redwood City, California | |
| Kaiser Permanente Sacramento Medical Center Sacramento, California | |
| Kings County Hospital Center Brooklyn, New York | |
| Lahey Hospital & Medical Center Burlington, Massachusetts | |
| Lehigh Valley Hospital - Cedar Crest Allentown, Pennsylvania | |
| Long Beach Memorial Medical Center Long Beach, California | |
| Los Alamitos Medical Center Los Alamitos, California | |
| Loyola University Medical Center Maywood, Illinois | |
| M Health Fairview University of Minnesota Medical Center Minneapolis, Minnesota | |
| Maimonides Medical Center Brooklyn, New York | |
| Maine Medical Center Scarborough, Maine | |
| Massachusetts General Hospital Boston, Massachusetts | |
| Mayo Clinic Rochester, Minnesota | |
| McLaren Flint Flint, Michigan | |
| McLaren Macomb Mount Clemens, Michigan | |
| MedStar Georgetown University Hospital Washington D.C., District of Columbia | |
| Medical University of South Carolina University Hospital Charleston, South Carolina | |
| Medstar Washington Hospital Center Washington D.C., District of Columbia | |
| Memorial Hermann Texas Medical Center Houston, Texas | |
| Mercy Hospital Oklahoma City Oklahoma City, Oklahoma | |
| Mercy Hospital South St Louis, Missouri | |
| Mercy Hospital Springfield Springfield, Missouri | |
| Mercy Hospital St. Louis St Louis, Missouri | |
| Mercy San Juan Medical Center Carmichael, California | |
| Methodist University Hospital Memphis, Tennessee | |
| Metro Health Hospital Wyoming, Michigan | |
| MetroHealth Medical Center Cleveland, Ohio | |
| Montefiore Medical Center The Bronx, New York | |
| Morton Plant Hospital Clearwater, Florida | |
| Moses H. Cone Memorial Hospital Greensboro, North Carolina | |
| Mount Sinai West New York, New York | |
| Munson Medical Center Traverse City, Michigan | |
| NCH Hospital, Arlington Heights Arlington Heights, Illinois | |
| NYC Health + Hospitals/Elmhurst Elmhurst, New York | |
| NYP Columbia University Medical Center New York, New York | |
| NYP Weill Cornell Medical Center New York, New York | |
| NYU Langone Hospital - Brooklyn Brooklyn, New York | |
| New Hanover Regional Medical Center Wilmington, North Carolina | |
| New Hanover Regional Medical Center Wilmington, North Carolina | |
| NewYork-Presbyterian Brooklyn Methodist Hospital Brooklyn, New York | |
| North Shore University Hospital Manhasset, New York | |
| OSF St. Francis Medical Center Peoria, Illinois | |
| OSU Wexner Medical Center Columbus, Ohio | |
| OU Medical Center Oklahoma City, Oklahoma | |
| Ochsner Medical Center - Main Campus New Orleans, Louisiana | |
| Oregon Health & Science University Hospital Portland, Oregon | |
| Overlook Medical Center Summit, New Jersey | |
| PIH Health Hospital - Whittier Whittier, California | |
| PeaceHealth Sacred Heart Medical Center - RiverBend Springfield, Oregon | |
| Penn State Hershey Medical Center Hershey, Pennsylvania | |
| Presbyterian Medical Center Philadelphia, Pennsylvania | |
| Providence St. Vincent Medical Center Portland, Oregon | |
| Rancho Los Amigos National Rehabilitation Center Downey, California | |
| Regions Hospital Saint Paul, Minnesota | |
| Rhode Island Hospital Providence, Rhode Island | |
| Riverside Methodist Hospital Columbus, Ohio | |
| Ronald Reagan UCLA Medical Center Los Angeles, California | |
| Rush University Medical Center Chicago, Illinois | |
| SUNY Upstate Medical University Syracuse, New York | |
| Saint Alphonsus Regional Medical Center - Boise Boise, Idaho | |
| San Francisco General Hospital San Francisco, California | |
| Santa Barbara Cottage Hospital Santa Barbara, California | |
| Semmes Murphey Main Campus Memphis, Tennessee | |
| St. Cloud Hospital Saint Cloud, Minnesota | |
| St. David's Medical Center Austin, Texas | |
| St. John Medical Center Tulsa, Oklahoma | |
| St. John's Hospital Springfield, Illinois | |
| St. Joseph's Hospital Tampa, Florida | |
| St. Joseph's Hospital and Medical Center Phoenix, Arizona | |
| St. Jude Medical Center Fullerton, California | |
| St. Mary's Medical Center Grand Junction, Colorado | |
| Stanford University Medical Center Palo Alto, California | |
| Staten Island University Hospital - North Campus Staten Island, New York | |
| Stony Brook University Hospital Stony Brook, New York | |
| Strong Memorial Hospital Rochester, New York | |
| Swedish Medical Center - Cherry Hill Campus Seattle, Washington | |
| Tampa General Hospital Tampa, Florida | |
| Temple University Hospital Philadelphia, Pennsylvania | |
| The Mount Sinai Hospital New York, New York | |
| The Queen's Medical Center Honolulu, Hawaii | |
| The University of Vermont Medical Center Burlington, Vermont | |
| Thomas Jefferson University Hospital Philadelphia, Pennsylvania | |
| Trinity Health Saint Mary's Grand Rapids, Michigan | |
| Trinity Health Saint Mary's Grand Rapids, Michigan | |
| Tufts Medical Center Boston, Massachusetts | |
| UAMS Medical Center Little Rock, Arkansas | |
| UC Davis Medical Center Sacramento, California | |
| UC Irvine Medical Center Orange, California | |
| UF Health Jacksonville Jacksonville, Florida | |
| UH Cleveland Medical Center Cleveland, Ohio | |
| UMass Memorial Medical Center Worcester, Massachusetts | |
| UPMC Presbyterian Hospital Pittsburgh, Pennsylvania | |
| UT Southwestern Medical Center Dallas, Texas | |
| UVA Medical Center Charlottesville, Virginia | |
| United Hospital, St. Paul Saint Paul, Minnesota | |
| University of Alabama Hospital Birmingham, Alabama | |
| University of Chicago Medical Center Chicago, Illinois | |
| University of Cincinnati Medical Center Cincinnati, Ohio | |
| University of Colorado Hospital Aurora, Colorado | |
| University of Illinois Hospital Chicago, Illinois | |
| University of Iowa Medical Center Iowa City, Iowa | |
| University of Kansas Hospital Kansas City, Kansas | |
| University of Kentucky Hospital Lexington, Kentucky | |
| University of Louisville Hospital Louisville, Kentucky | |
| University of Michigan University Hospital Ann Arbor, Michigan | |
| University of Mississippi Medical Center Jackson, Mississippi | |
| University of Missouri Health Care Columbia, Missouri | |
| University of Nebraska Medical Center Omaha, Nebraska | |
| University of New Mexico Hospital Albuquerque, New Mexico | |
| University of North Carolina Medical Center Chapel Hill, North Carolina | |
| University of South Alabama University Hospital Mobile, Alabama | |
| University of Texas Health Science Center San Antonio San Antonio, Texas | |
| University of Utah Healthcare Salt Lake City, Utah | |
| VCU Medical Center Richmond, Virginia | |
| Vanderbilt University Hospital Nashville, Tennessee | |
| Vassar Brothers Medical Center Poughkeepsie, New York | |
| Virginia Mason Medical Center Seattle, Washington | |
| Wake Forest Baptist Medical Center Winston-Salem, North Carolina | |
| Wellstar Kennestone Hospital Marietta, Georgia | |
| Westchester Medical Center Valhalla, New York | |
| Yale New Haven Hospital New Haven, Connecticut |
A Trial of Robotic Versus Open Hysterectomy Surgery in Cervix Cancer (ROCC)
Sarin Chhab - schhab@gog.org
NCT04831580
Show full eligibility criteria
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Inclusion Criteria:
• Patient must have histologically confirmed adenocarcinoma (usual/classic/NOS), squamous cell carcinoma, adenosquamous carcinoma (Including glassy cell)
• Patient must be FIGO Stage IA2, IBI, IB2 (2018 staging) without evidence of definitive parametrial, vaginal, nodal or distant metastases on exam or imaging. Patients with tumor size less than or equal to 4 cm confirmed on MRI prior to randomization are eligible.
• Patient must have uterine size \<12 cm AND felt to be appropriate for vaginal delivery of the specimen per investigator.
• Patient must be suitable surgical candidate with preoperative assessments such as labs and EKG performed per institutional standard and agree to be randomized to undergo open or robotic radical (or simple) hysterectomy. NOTE: Simple hysterectomy will be allowed in patients who meet the following criteria:
• pelvic MRI must demonstrate a maximal tumor size of 2 cm or less AND
• less than 50% stromal invasion on MRI if tumor present or less than 10 mm of stromal invasion if an excisional (cold knife or LEEP) has been performed. Submission of source documents in the GOG Partners Source Document Portal will be required prior to randomization for review and confirmation of simple hysterectomy being met (see Section 6.0 for instructions).
• Patient must be age 18 years or older.
• Patient must have ECOG performance status 0-1.
• Patient must have a negative urine pregnancy test within 30 days of surgery in pre-menopausal women.
• Patient must have signed an approved informed consent and authorization permitting the release of personal health information.
Exclusion Criteria:
• Patients with any tumor histology other than those listed above, specifically excluding the following histologies: neuroendocrine, other adenocarcinoma (gastric type, endometrioid, clear cell, serous, signet ring, minimal deviation)
• Patients with FIGO stage 1A1, IB3, II-IV (2018 staging).
• Patient with inability to receive an MRI.
• Patients with a tumor size greater than 4cm or on MRI confirmed prior to randomization are excluded. Patients with definite evidence of vaginal/parametrial involvement on MRI are excluded; if MRI findings are not definitive, then clinical examination must also not reveal parametrial or vaginal extension).
• Patients with evidence of metastatic disease (imaging or histologically positive lymph nodes).
• Patients with a history of prior pelvic or abdominal radiotherapy.
• Patients with a prior malignancy \< 5 years from enrollment with the exception of non-melanoma skin cancer.
• Patients who are unable to withstand prolonged lithotomy or steep trendelenberg.
• Patient compliance and geographic proximity that do not allow adequate follow-up.
• Patients with poorly controlled HIV with CD4 counts \<500.
DEVICE: da Vinci, OTHER: open surgery
Cervical Cancer
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See this study on ClinicalTrials.gov
Show 156 locations
Study Locations
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| Location | Contacts |
|---|---|
| A.C.Camargo Cancer Center São Paulo, São Paulo | Daniela Augustin - (daniela.augustin@lacogcancerresearch.org) |
| AHN West Penn Hospital Pittsburgh, Pennsylvania | - (janke.mainsmason@ahn.org) |
| Abington Memorial Hospital Abington, Pennsylvania | Ashley Douglas - (ashley.douglas@jefferson.edu) |
| Alliance Cancer Specialists, PC Wynnewood, Pennsylvania | Mark Shahin, MD - (mark.shahin@usoncology.com) |
| Asan Medical Center Seoul, | Dae Yeon Kim, MD - (kdyog@amc.seoul.kr) |
| Ascension Medical Group St. Vincent's Obstetrics and Gynecology Jacksonville, Florida | Nicole Antenucci - (nicole.antenucci@ascension.org) |
| Asplundh Cancer Pavillion Willow Grove, Pennsylvania | Ashley Douglas - (ashley.douglas@jefferson.edu) |
| Baptist Health Lexington, Kentucky | Lauren Higgins - (lauren.higgins@bhsi.com) |
| Baptist Health Lexington Lexington, Kentucky | Lauren Higgins - (lauren.higgins@bhsi.com) |
| Barretos Cancer Hospital Barretos, São Paulo | Daniela Augustin - (daniela.augustin@lacogcancerresearch.org) |
| Baystate Medical Center Springfield, Massachusetts | |
| Brazilian National Cancer Institute Rio de Janeiro, | Gustavo Guitmann, PhD - (Guitmann@clinicagincol.com.br) |
| CHA Bundang Medical Center Gyeonggi-do, | Hyun Park, MD - (p06162006@cha.ac.kr) |
| California Pacific Medical Center-Research Institute San Francisco, California | |
| Center of Hope Reno, Nevada | Shannon White Pierpoint - (spierpoint@cohreno.com) |
| Centre Hospitalier de l'Université de Montréal Montreal, | Mathilde Duplaix - (mathilde.duplaix.chum@ssss.gouv.qc.ca) |
| Chattanooga's Program in Women's Oncology Chattanooga, Tennessee | Kimberly Donelson - (Kimberly.Donelson@erlanger.org) |
| City of Hope Duarte, California | Raechelle Tinsley - (RTinsley@coh.org) |
| City of Hope - Upland Upland, California | Raechelle Tinsley - (rtinsley@coh.org) |
| City of Hope Orange County Lennar Foundation Cancer Irvine, California | Raechelle Tinsley - (rtinsley@coh.org) |
| David C. Pratt Center St Louis, Missouri | Crystal Tindall - (crystal.tindall@mercy.net) |
| Duke Cancer Center Durham, North Carolina | Taylor Hayes - (taylor.hayes@duke.edu) |
| Duke Cancer Center Durham, North Carolina | Lauren March - (lauren.march@duke.edu) |
| Duke University Hospital Durham, North Carolina | Taylor Hayes - (taylor.hayes@duke.edu) |
| FirstHealth Outpatient Cancer Center Pinehurst, North Carolina | |
| Gangnam Severance Hospital Seoul, | JaeHoon Kim - (jaehoonkim@yuhs.ac) HyunJin Lee - (pistis@yuhs.ac) |
| Georgian Cancer Center at Augusta University Augusta, Georgia | Angela Goebel - (agoebel@augusta.edu) |
| Harford HealthCare Cancer Institute at the Hospital of Central Connecticut New Britain, Connecticut | Siobhan Reilly - (mailto:siobhan.reilly@hhchealth.org) |
| Hartford Healthcare Cancer Institute at Hartford Hospital Hartford, Connecticut | Siobhan Reilly - (mailto:siobhan.reilly@hhchealth.org) |
| Hartford Healthcare Medical Group-Manchester Manchester, Connecticut | Siobhan Reilly - (mailto:siobhan.reilly@hhchealth.org) |
| Hartford Hospital Hartford, Connecticut | Siobhan Reilly - (mailto:siobhan.reilly@hhchealth.org) |
| Hoag Gynecologic Oncology Newport Beach, California | Ana Navarrete - (ana.navarrete@hoag.org) |
| Hoag Memorial Hospital Presbyterian Newport Beach, California | Ana Navarrete - (ana.navarrete@hoag.org) |
| Hospital Erasto Gaertner Curitiba, | Erik M Coelho - (erik.coelho@lacog.group) Audrey Tsunoda, MD - (atsunoda@gmail.com) |
| Hospital Municipal Vila Santa Catarina São Paulo, Sao Paula | Renato Moretti-Marques, MD - (renato.moretti@einstein.br) |
| Hospital de Base - Fundacao Faculdade Regional de Medicina de São José do Rio Preto São José do Rio Preto, São Paulo | Carlos E Andrade, MD - (mdcarlosandrade@gmail.com) Erik Coelho - (erik.coelho@lacog.group) |
| Inova Health System Fairfax, Virginia | Takada Harris - (takada.harris@inova.org) |
| James Cancer Hospital & Solove Research Institute at The Ohio State University Comprehensive Cancer Center Columbus, Ohio | Callan Myercough - (callan.myerscough@osumc.edu) |
| JamesCare Gynecologic Oncology at Mill Run Hilliard, Ohio | Callan Myerscough - (macallan.myerscough@osumc.edu) |
| Josie Robertson Surgery Center New York, New York | Josie Anderson - (andersj@mskcc.org) |
| Kettering Health Cancer Center Kettering, Ohio | Julie Carstens - (julie.carstens@ketteringhealth.org) |
| Korea University Anam Hospital Seongbuk-Gu, | Jae-Yun Song, MD - (sjyuni105@gmail.com) |
| Korea University Guro Hospital Seoul, | Sohyeon Jeong, MD - (shj9918@gmail.com) |
| LSU Health New Orleans New Orleans, Louisiana | Dina Brackman - (dbrack@lsuhsc.edu) |
| Laura and Issac Perlmutter Cancer Center at NYU Langone New York, New York | Kathryn Allen - (mailto:Kathryn.Allen@nyulangone.org) |
| Laura and Issac Perlmutter Cancer Center at NYU Langone New York, New York | Kathryn Allen - (mailto:Kathryn.Allen@nyulangone.org) |
| Laura and Issac Perlmutter Cancer Center at NYU Langone-East 34th Street New York, New York | Kathryn Allen - (mailto:Kathryn.Allen@nyulangone.org) |
| Legacy Good Samaritan Medical Center-Gynecological Oncology Group Portland, Oregon | |
| Legacy Meridian Park Medical Center-Legacy Medical Gynecologic Oncology Tualatin, Oregon | |
| Legacy Salmon Creek Medical Center-Legacy Medical Group Gynecologic Oncology Vancouver, Washington | |
| M Health Fairview University of Minnesota Medical Center-East Bank Hospital Minneapolis, Minnesota | Erin Zielinksi - (eezielin@umn.edu) |
| M Health Fairview University of Minnesota Medical Center-East Bank Hospital Minneapolis, Minnesota | Erin Zielinksi - (eezielin@umn.edu) |
| Magee - Womens Hospital of UPMC Pittsburgh, Pennsylvania | Jessica Yauch - (yauchj@upmc.edu) |
| Maine Medical Partners-Woman's Health-Division of Gynecologic Oncology Scarborough, Maine | Robin Donovan - (donovr@mmc.org) |
| McGill University Health Centre-Glen Site Montreal, Quebec | Phuong-Nam Nguyen - (mailto:phuong-nam.nguyen@mail.mcgill.ca) |
| Memorial Sloan Kettering (Basking Ridge) Basking Ridge, New Jersey | Josie Anderson - (andersj@mskcc.org) |
| Memorial Sloan Kettering (Bergen) Montvale, New Jersey | Josie Anderson - (andersj@mskcc.org) |
| Memorial Sloan Kettering (Commack) Commack, New York | Josie Anderson - (andersj@mskcc.org) |
| Memorial Sloan Kettering (Monmouth) Middletown, New York | Josie Anderson - (andersj@mskcc.org) |
| Memorial Sloan Kettering (Nassau) Uniondale, New York | Josie Anderson - (andersj@mskcc.org) |
| Memorial Sloan Kettering (Westchester) Harrison, New York | Josie Anderson - (andersj@mskcc.org) |
| Memorial Sloan Kettering Cancer Center (Main Campus) New York, New York | Josie Anderson - (mailto:andersj@mskcc.org) |
| Mercy Hospital Coon Rapids, Minnesota | Jennifer Mosley - (Jennifer.mosley@hcahealthcare.com) |
| Mercy Hospital Coon Rapids, Minnesota | Jennifer Mosley - (Jennifer.mosley@hcahealthcare.com) |
| Miami Cancer Institute at Baptist Health, Inc. Miami, Florida | Jacqueline Lebron - (jacquelile@baptisthealth.net) |
| Miami Cancer Institute at Baptist Health, Inc. Miami, Florida | Stephany Fuentes Angulo - (Stephany.FuentesAngulo@baptisthealth.net) |
| Minnesota Oncology Hematology Minneapolis, Minnesota | Jessica Thomes-Pepin - (jessica.thomespepin@usoncology.com) |
| Mount Sinai Comprehensive Cancer Center Miami Beach, Florida | |
| NHPP/Gynecologic Oncology at New Hyde Park New Hyde Park, New York | Batool Mubashar - (mailto:bmubashar@northwell.edu) |
| NYU Langone Ambulatory Care Bay Ridge Brooklyn, New York | Kathryn Allen - (mailto:Kathryn.Allen@nyulangone.org) |
| NYU Langone Hospital-Brooklym Brooklyn, New York | Kathryn Allen - (mailto:Kathryn.Allen@nyulangone.org) |
| NYU Langone Medical Center (Tisch Hospital) New York, New York | Kathryn Allen - (mailto:Kathryn.Allen@nyulangone.org) |
| Northwell Health Physician Partners/Gynecological Oncology at Brightwaters Brightwaters, New York | Batool Mubashar - (mailto:bmubashar@northwell.edu) |
| Northwell Health/Huntington Hospital Huntington, New York | Batool Mubashar - (mailto:bmubashar@northwell.edu) |
| Northwell Health/Long Island Jewish Medical Center New Hyde Park, New York | Batool Mubashar - (mailto:bmubashar@northwell.edu) |
| Northwell Health/South Shore University Hospital Bay Shore, New York | Batool Mubashar - (mailto:bmubashar@northwell.edu) |
| Novant Health Cancer Institute Charlotte, North Carolina | - (kashah@novanthealth.org) |
| Novant Health Cancer Institute Charlotte, North Carolina | - (kashah@novanthealth.org) |
| Novant Health Cancer Institute Charlotte, North Carolina | - (kashah@novanthealth.org) |
| Novant Health Cancer Institute Charlotte, North Carolina | - (kashah@novanthealth.org) |
| Novant Health Cancer Institute Charlotte, North Carolina | - (kashah@novanthealth.org) |
| Novant Health Cancer Institute Charlotte, North Carolina | - (kashah@novanthealth.org) |
| Novant Health Cancer Institute Charlotte, North Carolina | - (kashah@novanthealth.org) |
| Novant Health Cancer Institute Charlotte, North Carolina | - (kashah@novanthealth.org) |
| OSU Wexner Medical Center Hospital East Columbus, Ohio | Callan Myerscough - (callan.myerscough@osumc.edu) |
| OSU Wexner Medical Center Martha Morehouse Outpatient Care Columbus, Ohio | Callan Myerscough - (callan.myerscough@osumc.edu) |
| OSU Wexner Medical Center Outpatient Care Dublin Dublin, Ohio | Callan Myerscough - (callan.myerscough@osumc.edu) |
| OSU Wexner Medical Center Outpatient Care East Columbus, Ohio | Callan Myserscough - (callan.myerscough@osumc.edu) |
| OSU Wexner Medical Center Outpatient Care Gahanna Columbus, Ohio | Callan Myerscough - (callan.myerscough@osumc.edu) |
| OSU Wexner Medical Center Outpatient Care Lewis Center Lewis Center, Ohio | Callan Myerscough - (callan.myerscough@osumc.edu) |
| OSU Wexner Medical Center Outpatient Care New Albany Westerville, Ohio | Callan Myerscough - (callan.myerscough@osumc.edu) |
| OSU Wexner Medical Center Outpatient Care Upper Arlington Columbus, Ohio | Callan Myerscough - (callan.myerscough@osumc.edu) |
| OSU Wexner Medical Center Stefanie Spielman Comprehensive Breast Center Columbus, Ohio | Callan Myerscough - (callan.myerscough@osumc.edu) |
| OSU Wexner Medical Center University Hospital Columbus, Ohio | Callan Myerscough - (callan.myerscough@osumc.edu) |
| Orlando Health Cancer Center Orlando, Florida | |
| Orlando Health Winnie Palmer Hospital for Woman and Babies Orlando, Florida | |
| Palo Alto Medical Foundation Palo Alto, California | |
| Princess Margaret Cancer Center Toronto, Ontario | Vanessa Ballin - (Vanessa.Ballin@uhn.ca) Sarah Ferguson, MD - (sarah.ferguson@uhn.ca) |
| Providence Center Institute Franz Clinic Portland, Oregon | Nora Auston - (Nora.Auston@providence.org) |
| Samsung Medical Center Seoul, | Chel Hun Choi, PhD - (chelhun.choi@samsung.com) |
| Seoul National University Bundang Hospital Seongnam-si, Gyeonggi-do | Dong Hoon Suh, MD - (sdhwcj@naver.com) |
| Seoul St. Mary's Hospital - Catholic University Seoul, | Sung Jong Lee, MD - (orlando@catholic.ac.kr) |
| Severance Hospital - Yonsei Cancer Center Seoul, | Ji Won, Woo - (te05028@yuhs.ac) Sang-wun Kim, MD, PhD - (san1@yuhs.ac) |
| Severance Hospital - Yonsei Cancer Center Seoul, | Sangwun Kim, MD - (san1@yuhs.ac) |
| South Miami Hospital Miami, Florida | Jacqueline Lebron - (jacquelile@baptisthealth.net) |
| South Miami Hospital Miami, Florida | Stephany Fuentes Angulo - (Stephany.FuentesAngulo@baptisthealth.net) |
| Southeastern Regional Medical Center LLC Newnan, Georgia | |
| St. Elizabeth Healthcare Edgewood, Kentucky | |
| St. Vincent Hospital and Health Care Center Inc Indianapolis, Indiana | |
| St. Vincent Hospital and Health Care Center, Inc Indianapolis, Indiana | |
| Stanford Hospital Stanford, California | Samya Konda - (skonda@stanford.edu) |
| Stephenson Cancer Center Oklahoma City, Oklahoma | Morgan Hays - (mailto:morgan-hays@ouhsc.edu) |
| Summa Health Jean and Milton Copper Pavilion Akron, Ohio | Danielle McCutcheon - (mccutcheond@summahealth.org) |
| Summa Health Jean and Milton Copper Pavillion Akron, Ohio | Danielle McCutcheon - (mamccutcheond@summahealth.org) |
| Tampa General Hospital Tampa, Florida | |
| Texas Oncology San Antonio, Texas | Nori Sullivan - (mailto:nori.sullivan@usoncology.com) |
| Texas Oncology- Baylor Charles A. Sammons Cancer Center Dallas, Texas | Christine Terraciano - (christine.terraciano@usoncology.com) |
| Texas Oncology- GYN ONC DFWW Bedford, Texas | Nori Sullivan - (mailto:nori.sullivan@usoncology.com) |
| Texas Oncology-Austin Austin, Texas | Kelli Watkins - (kelli.watkins@mckesson.com) |
| Texas Oncology-DFWW Bedford, Texas | Sarah Wade - (mailto:Sarah.Wade@usoncology.com) |
| Texas Oncology-GYN ONC DFWW Fort Worth, Texas | Nori Sullivan - (mailto:nori.sullivan@usoncology.com) |
| Texas Oncology-San Antonio San Antonio, Texas | Riquanda Walker - (Riquanda.Walker@McKesson.com) |
| Texas Oncology-The Woodlands, Gynecologic Oncology The Woodlands, Texas | Kelli Watkins - (Kelli.Watkins@mckesson.com) |
| The Blavatnik Family - Chelsea Medical Center at Mount Sinai New York, New York | Neha Kumarley - (Kuneha.kumarley@mssm.edu) |
| The West Clinic, PLLC dba West Cancer Center Germantown, Tennessee | Joslyn Walker - (jowalker@westclinic.com) |
| TriHealth Cancer Institute-Good Samaritan Hospital Cincinnati, Ohio | |
| TriHealth Cancer Institute-Thomas Comprehensive Care Center Cincinnati, Ohio | |
| UCLA Gynecologic Oncology Clinic Los Angeles, California | Dana Chase, MD - (dmchase@mednet.ucla.edu) |
| University of California San Diego Medical Center La Jolla, California | - (aocronin@health.ucsd.edu) |
| University of California San Diego Medical Center La Jolla, California | - (aocronin@health.ucsd.edu) |
| University of California San Diego Medical Center La Jolla, California | - (aocronin@health.ucsd.edu) |
| University of California San Diego Medical Center La Jolla, California | - (aocronin@health.ucsd.edu) |
| University of California San Diego Moores Cancer Center La Jolla, California | - (aocronin@health.ucsd.edu) |
| University of Cleveland Medical Center Cleveland, Ohio | Lauren Patrick - (Lauren.Patrick@uhhospitals.org) |
| University of New Mexico Comprehensive Cancer Center Albuquerque, New Mexico | |
| University of Pennsylvania Health System, Perelman Center for Advanced Medicine Philadelphia, Pennsylvania | Christine Yang - (christine.yang@pennmedicine.upenn.edu) |
| University of Texas Southwestern Medical Center Dallas, Texas | Annette Paulsen - (mailto:Annette.Paulsen@UTSouthwestern.edu) |
| University of Texas Southwestern Medical Center-Simmons Cancer Center Dallas, Texas | Annette Paulsen - (mailto:Annette.Paulsen@UTSouthwestern.edu) |
| University of Texas Southwestern Medical Center-WIlliam P. Clements Jr. University Hospital Dallas, Texas | Annette Paulsen - (Annette.Paulsen@UTSouthwestern.edu) |
| University of Texas Southwestern Medical Center-Zale Lipshy University Hospital Dallas, Texas | Annette Paulsen - (Annette.Paulsen@UTSouthwestern.edu) |
| University of Virginia Charlottesville, Virginia | Rachel Lacy - (rmc9p@hscmail.mcc.virginia.edu) |
| University of Virginia Comprehensive Cancer Center Charlottesville, Virginia | Rachel Lacy - (mrmc9p@hscmail.mcc.virginia.edu) |
| University of Wisconsin Clinical Science Center Madison, Wisconsin | Claire Kostechka - (kostechka@wisc.edu) |
| VCU Health Emergency Center at New Kent Quinton, Virginia | Sonya Washington - (mailto:slwashington@vcu.edu) |
| VCU Health Short Pump Pavillion Richmond, Virginia | Sonya Washington - (mailto:slwashington@vcu.edu) |
| VCU Health at GreenGate Henrico, Virginia | Sonya Washington - (slwashington@vcu.edu) |
| VCU Health at Tappahannock Hospital Tappahannock, Virginia | |
| VCU Health-William and Mary Williamsburg, Virginia | Sonya Washington - (mailto:slwashington@vcu.edu) |
| VCU Massey Cancer Center at Stony Point Richmond, Virginia | Sonya Washington - (mailto:slwashington@vcu.edu) |
| Virginia Commonwealth University Massey Cancer Center Richmond, Virginia | Sonya Washington - (mailto:slwashington@vcu.edu) |
| Virginia Commonwealth University-Main Hospital Richmond, Virginia | Sonya Washington - (mailto:slwashington@vcu.edu) |
| West Virginia Morgantown, West Virginia | Christina Martinelli - (mailto:christina.martinelli@hsc.wvu.edu) |
| West Virginia University Morgantown, West Virginia | Christina Martinelli - (mailto:christina.martinelli@hsc.wvu.edu) |
| Western Regional Medical Center LLC Goodyear, Arizona | |
| Willis-Knighton Physician Network Gynecologic Oncology Associates Shreveport, Louisiana | Carrie Key, RN - (ckay@wkhs.com) |
| Women's and Infants Hospital of Rhode Island Program in Women's Oncology Providence, Rhode Island | Ann John - (ajohn@wihri.org) |
Predicting Outcomes in Nonalcoholic Steatohepatitis With Advanced Fibrosis
Mohammad S Siddiqui, MD - mohammad.siddiqui@vcuhealth.org
NCT05720663
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Inclusion Criteria:
Adult patients with presence of NAFLD associated cirrhosis.
* Cirrhosis: biopsy confirmed or Agile F (F4) score \> 0.45
* NAFLD as an etiology of liver disease will be determined based on presence of any of the following:
* Biopsy showing \>5% steatosis or
* CAP \> 280 dB/m or MR-PDFF\>5%
* If CAP \< 280 dB/m or MR-PDFF \<5%, then must have type 2 diabetes and or 2 or more features of metabolic syndrome for 5 years (cryptogenic cirrhosis)
Exclusion Criteria:
* Refusal to consent
* Alcohol use \> 14/21 gm/week cutoff
* Other causes of chronic liver disease
* MELD \> 12
* Hepatic and extrahepatic cancers expected to limit life expectancy \< 2 yrs
* prior hepatic resections, TIPS, splenic embolization
* prior decompensation events
* inability to fit into MRI (failed hula-hoop test)
* general contraindication for MRI contrast (GFR \< 30 ml/min)
* contraindications for MRI
* pregnancy
* acute kidney injury
* reduced kidney function (GFR \<30ml/min) OTHER: Standard of care
Nonalcoholic Steatohepatitis
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See this study on ClinicalTrials.gov
Show 2 locations
Study Locations
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| Location | Contacts |
|---|---|
| Mayo Clinic in Rochester Rochester, Minnesota | Christopher Kigongo - (Kigongo.Christopher@mayo.edu) Mia Mahmoud - (Mahmoud.Mia@mayo.edu) |
| Virginia Commonwealth University Richmond, Virginia | Mohammad Siddiqui, MD - (mohammad.siddiqui@vcuhealth.org) |
BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study
ctrrecruit@vcu.edu
NCT05136196
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Inclusion Criteria:
* STEP 1 - SPECIMEN SUBMISSION
* Participants must have histologically confirmed melanoma that is stage III or IV, unresectable, recurrent, or metastatic non-uveal melanoma OR Participants must have histologically confirmed squamous cell carcinoma of the head and neck (HNSCC) that is either locally recurrent and non-amendable to curative therapy (e.g., radiation, surgery) or metastatic. The primary tumor location must be the oropharynx, oral cavity, hypopharynx, or larynx. Primary tumor site of nasopharynx (any histology) or unknown primary tumor are not eligible
* Note: For participants with primary oropharyngeal cancer, human papillomavirus (HPV) or p16 status must be known prior to step 1 registration
* Participants must have disease presentation consistent with measurable disease. Note: Current disease measurements will not be required until step 2 registration
* Participants must have had documented progression during or within 12 weeks after the last dose of PD-1 checkpoint inhibition-based therapy. Participants must have been receiving checkpoint inhibition for a minimum of 6 weeks. Participants who recur during adjuvant anti-PD1 treatment or within 12 weeks of completion of adjuvant anti-PD1 treatment are eligible if they have measurable disease and are considered unresectable
* Participants with known human immunodeficiency virus (HIV)-infection must be receiving anti-retroviral therapy and have an undetectable viral load test within 6 months prior to step 1 registration
* Participants with evidence of chronic hepatitis B virus (HBV) infection must have undetectable HBV viral load within 28 days prior to step 1 registration
* Participants with a history of hepatitis C virus (HCV) infection must have no detectable viral load within 28 days prior to step 1 registration
* Participants must not have an active infection requiring systemic therapy (except HBV, HCV or HIV as mentioned above)
* Participants must not have experienced myocardial infarction or thromboembolic event requiring anticoagulation within 90 days prior to step 1 registration, unless clinically stable with ongoing medical management
* Participants must have recovered to baseline or =\< grade 1 Common Terminology Criteria for Adverse Events (CTCAE) version (v) 5 toxicities related to any prior treatments, unless adverse events are deemed clinically nonsignificant by the treating investigator or stable on supportive therapy
* Participants must not have received more than one prior primary radiotherapy regimen, curative or adjuvant, to the mucosal surfaces of the head and neck, with the additional following criteria:
* If the primary radiation is combined with chemotherapy, a minimum of 16 weeks will be required to have elapsed between the end of radiotherapy and step 1 registration. If the radiation is given alone, a minimum of 8 weeks will be required to have elapsed between the end of radiotherapy and step 1 registration
* Additional palliative radiotherapy regimens are permitted but cannot have been administered to previously treated tissue (i.e., overlapping fields are excluded) with the exception of central nervous system (CNS) radiation and must be completed at least 4 weeks prior to step 1 registration
* Treatment areas should be healed with no sequelae from radiation therapy (RT) that would predispose to fistula formation
* Participants must not have received prior treatment with anti-VEGF therapies for any reason
* Participants must be \>= 18 years of age
* Participants must have a Zubrod Performance Status 0 or 1
* Participants must have adequate cardiac function. Participants with known history or current symptoms of cardiac disease, or history of treatment with cardiotoxic agents, must have a clinical risk assessment of cardiac function using the New York Heart Association Functional Classification and must be class 2B or better to be eligible for this trial
* Participants must not have any known significant organ disfunction that, in the opinion of the treating investigator, may impact suitability for receiving combination nivolumab/cabozantinib treatment
* Participants must be able to take oral medication without breaking, opening, crushing, dissolving or chewing capsules
* Participants must not have malabsorption syndrome
* Participants must not have active autoimmune disease requiring systemic steroids (equivalent of \> 10mg of prednisone) or other immune suppression. Exceptions:
* Type 1 diabetes mellitus
* Endocrinopathy only requiring hormone replacement
* Skin disorders (e.g., vitiligo, psoriasis, or alopecia) not requiring systemic treatment
* Conditions not expected to recur in the absence of an external trigger
* Participants must not have received an organ allograft
* Participants must not have a history of hemoptysis (defined as \>= 1/2 tsp of bright red blood per day) or tumor bleeding within 90 days prior to step 1 registration
* Participants must not have any of the following criteria due to the possibility of increased risk for tumor bleeding with cabozantinib therapy:
* Prior carotid bleeding
* Tumors that invade major vessels (e.g., the carotid) as shown unequivocally by imaging studies
* Central (e.g., within 2 cm from the hilum) lung metastases that are cavitary as shown unequivocally by imaging studies
* Any prior history of bleeding related to the current head and neck cancer
* History of gross hemoptysis (bright red blood of 1/2 teaspoon or more per episode of coughing) within 3 months
* Participants must not require concomitant anticoagulation with coumarin agents (e.g., warfarin), direct thrombin inhibitors (e.g., dabigatran), direct factor Xa inhibitor betrixaban, or platelet inhibitors (e.g., clopidogrel)
* Participants must not require anticoagulants except for the following:
* Prophylactic use of low-dose aspirin for cardio-protection (per local applicable guidelines) and low-dose low molecular weight heparins (LMWH).
* Therapeutic doses of LMWH or anticoagulation with direct factor Xa inhibitors, rivaroxaban, edoxaban, or apixaban in participants without known brain metastases who are on a stable dose of the anticoagulant for at least 1 week prior to step 1 registration without clinically significant hemorrhagic complications from the anticoagulation regimen or the tumor
* Participants must not have evidence of preexisting uncontrolled hypertension 28 days prior to step 1 registration as documented by baseline blood pressure reading with systolic blood pressure \> 150 mmHg and/or diastolic blood pressure \> 90 mmHg. Participants on antihypertensive therapies with controlled blood pressure are eligible
* Participants must not have a prior or concurrent malignancy whose natural history or treatment (in the opinion of the treating physician) has the potential to interfere with the safety or efficacy assessment of the investigational regimen
* Participants must not be pregnant or nursing due to the known safety profiles of the drugs in this study. Individuals who are of reproductive potential must have agreed to use an effective contraceptive method with details provided as a part of the consent process. A person who has had menses at any time in the preceding 12 consecutive months or who has semen likely to contain sperm is considered to be of "reproductive potential". In addition to routine contraceptive methods, "effective contraception" also includes refraining from sexual activity that might result in pregnancy and surgery intended to prevent pregnancy (or with a side-effect of pregnancy prevention) including hysterectomy, bilateral oophorectomy, bilateral tubal ligation/occlusion and vasectomy with testing showing no sperm in the semen
* Have an adequate archival tissue specimen verified by the local pathologist and documented on the Pathology Review Form from a procedure obtained after the development of resistance to anti-PD-1/L1 therapy. Archival tissue must consist of tumor block or at least 1 hematoxylin and eosin (H\&E)-stained 4-5 micron slide and 20 freshly cut serially sectioned and numbered 4-5 micron unstained, uncharged slides OR
Be willing to undergo research biopsy AND have tumor accessible for biopsy based on the following criteria:
* Mediastinal, laparoscopic, gastrointestinal, or bronchial endoscopic biopsies can be obtained incidentally to a clinically necessary procedure and NOT for the sole purpose of the clinical trial
* Acceptable biopsy procedures are:
* Percutaneous biopsy with local anesthetic and/or sedation with an expected risk of severe complications \< 2%
* Direct transoral biopsy (with or without local anesthetic and/or sedation) with an expected risk of severe complications \< 2%
* Excisional cutaneous biopsy with local anesthetic and/or sedation with an expected risk of severe complications \< 2%
* Biopsy with removal of additional tumor tissue during a medically necessary mediastinoscopy, laparoscopy, gastrointestinal endoscopy, bronchoscopy or craniotomy. No open surgical, laparoscopic or endoscopic procedure should be performed solely to obtain a biopsy for this protocol
* Removal of additional tumor tissue during a medically necessary surgical procedure
* Participants must submit whole blood for germline genomic analysis
* Participants must have been offered the opportunity to participate in specimen banking
* Note: As a part of the Oncology Patient Enrollment Network (OPEN) registration process the treating institution's identity is provided in order to ensure that the current (within 365 days) date of institutional review board approval for this study has been entered in the system
* Participants must be informed of the investigational nature of this study and must sign and give informed consent in accordance with institutional and federal guidelines
* Participants with impaired decision-making capacity are eligible as long as their neurological or psychological condition does not preclude their safe participation in the study (e.g., tracking pill consumption and reporting adverse events to the investigator)
* STEP 2 TREATMENT REGISTRATION
* Note: No tests or exams are required to be repeated for step 2 registration (Treatment). However, participants who are known to have a change in eligibility status after step 1 registration are not eligible for step 2 registration
* Participants must continue to meet eligibility for step 1 registration prior to step 2 registration
* Participants must have had their tumor tissue submitted via the Southwest Oncology Group (SWOG) Specimen Tracking System prior to step 2 registration
* Participants registered during stage II of the protocol must have received assignment to an open cohort from the SWOG Statistics and Data Management Center based on their biomarker screening profile (not applicable for patients registered during stage I of the protocol)
* Participants must have measurable disease. All measurable disease must be assessed within 28 days prior to step 2 registration. All non-measurable disease must be assessed within 42 days prior to step 2 registration. Note: All disease must be assessed and documented on the Baseline Tumor Assessment Form (Response Evaluation Criteria in Solid Tumors \[RECIST\] 1.1)
* For melanoma participants, CT chest, abdomen and pelvis must be obtained. For HNSCC participants, CT neck and chest must be obtained. Further imaging (i.e., MR brain, CT abdomen/pelvis or extremities, bone scan) will be performed as deemed appropriate by the treating physician
* Participants with treated brain metastases must have no evidence of progression on the follow-up brain imaging after central nervous system (CNS)-directed therapy
* Participants must not have experienced any significant health changes that, in the opinion of the treating investigator, may impact continued suitability for receiving combination nivolumab/cabozantinib treatment
* Participants with treated brain metastases must have discontinued steroid treatment at least 14 days prior to step 2 registration
* Participants must not have received investigational agents or monoclonal antibodies (except Food and Drug Administration \[FDA\] approved supportive care antibodies, such as denosumab) within 28 days prior to step 2 registration
* Participants must not have received surgery, chemotherapy, radiation therapy, biologic agents, or steroids within 14 days prior to step 2 registration
* Participants must not have received administration of a live, attenuated vaccine within 30 days prior to step 2 registration. Note: Participants may have received a messenger ribonucleic acid (mRNA) or viral vector-based coronavirus disease 2019 (COVID-19) vaccine within 30 days prior to step 2 registration
* Participants must not have received administration of any strong CYP3A4 inducers, such as but not limited to rifampin, carbamazepine, enzalutamide, mitotane, phenytoin and St. John's wort, within 14 days prior to step 2 registration
* Participants must not have received administration of any strong CYP3A4 inhibitors, such as but not limited to clarithromycin, itraconazole, ketoconazole, grapefruit juice, indinavir, nelfinavir, ritonavir, nefazodone, saquinavir, and telithromycin, within 5 times the half-life of the CYP3A inhibitor prior to step 2 registration
* Participants must have a history and physical examination performed within 28 days prior to step 2 registration
* Leukocytes \>= 3,000/uL (within 28 days prior to step 2 registration)
* Absolute neutrophil count \>= 1,500/uL (within 28 days prior to step 2 registration)
* Platelets \>= 100,000/uL (within 28 days prior to step 2 registration)
* Total bilirubin =\< 1.5 x institutional upper limit of normal (ULN) or =\< 3 x ULN for participants with Gilbert's disease (within 28 days prior to step 2 registration)
* Aspartate aminotransferase (AST) =\< 3 x institutional ULN (within 28 days prior to step 2 registration)
* Alanine aminotransferase (ALT) =\< 3 x institutional ULN (within 28 days prior to step 2 registration)
* Urinalysis: For baseline value (no required value for eligibility)
* Measured (OR calculated) creatinine clearance \>= 30 mL/min using the following Cockcroft-Gault Formula. This specimen must have been drawn and processed within 28 days prior to step 2 registration PROCEDURE: Biopsy Procedure, PROCEDURE: Biospecimen Collection, DRUG: Cabozantinib S-malate, PROCEDURE: Computed Tomography, PROCEDURE: Magnetic Resonance Imaging, BIOLOGICAL: Nivolumab
Clinical Stage III Cutaneous Melanoma AJCC v8, Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage IV Cutaneous Melanoma AJCC v8, Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Locally Recurrent Head and Neck Squamous Cell Carcinoma, Locally Recurrent Hypopharyngeal Squamous Cell Carcinoma, Locally Recurrent Laryngeal Squamous Cell Carcinoma, Locally Recurrent Oral Cavity Squamous Cell Carcinoma, Locally Recurrent Oropharyngeal Squamous Cell Carcinoma, Metastatic Head and Neck Squamous Cell Carcinoma, Metastatic Hypopharyngeal Squamous Cell Carcinoma, Metastatic Laryngeal Squamous Cell Carcinoma, Metastatic Melanoma, Metastatic Oral Cavity Squamous Cell Carcinoma, Metastatic Oropharyngeal Squamous Cell Carcinoma, Recurrent Melanoma, Stage III Hypopharyngeal Carcinoma AJCC v8, Stage III Laryngeal Cancer AJCC v8, Stage III Lip and Oral Cavity Cancer AJCC v8, Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8, Stage IV Hypopharyngeal Carcinoma AJCC v8, Stage IV Laryngeal Cancer AJCC v8, Stage IV Lip and Oral Cavity Cancer AJCC v8, Stage IV Oropharyngeal (p16-Negative) Carcinoma AJCC v8, Unresectable Melanoma
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Show 230 locations
Study Locations
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| Location | Contacts |
|---|---|
| Abbott-Northwestern Hospital Minneapolis, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Asplundh Cancer Pavilion Willow Grove, Pennsylvania | |
| Atrium Medical Center-Middletown Regional Hospital Franklin, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Baystate Medical Center Springfield, Massachusetts | Site Public Contact - (tamara.wrenn@baystatehealth.org) |
| Beacon Kalamazoo Cancer Center Kalamazoo, Michigan | |
| Benefis Sletten Cancer Institute Great Falls, Montana | Site Public Contact - (mccinfo@mtcancer.org) |
| Billings Clinic Cancer Center Billings, Montana | Site Public Contact - (research@billingsclinic.org) |
| Bozeman Health Deaconess Hospital Bozeman, Montana | Site Public Contact - (mccinfo@mtcancer.org) |
| Bronson Battle Creek Battle Creek, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
| Bronson Methodist Hospital Kalamazoo, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
| Cancer Care Center of O'Fallon O'Fallon, Illinois | Site Public Contact - (morganthaler.jodi@mhsil.com) |
| Cancer Care Specialists of Illinois - Decatur Decatur, Illinois | Site Public Contact - (morganthaler.jodi@mhsil.com) |
| Cancer Care and Hematology-Fort Collins Fort Collins, Colorado | Site Public Contact - (protocols@swog.org) |
| Cancer Center of Western Wisconsin New Richmond, Wisconsin | Site Public Contact - (mmcorc@healthpartners.com) |
| Cancer Hematology Centers - Flint Flint, Michigan | Site Public Contact - (wstrong@ghci.org) |
| Cancer and Hematology Centers of Western Michigan - Norton Shores Norton Shores, Michigan | |
| Carle BroMenn Medical Center Normal, Illinois | Site Public Contact - (Research@Carle.com) |
| Carle Cancer Center Urbana, Illinois | Site Public Contact - (Research@carle.com) |
| Carle Cancer Institute Normal Normal, Illinois | Site Public Contact - (Research@Carle.com) |
| Carle Physician Group-Effingham Effingham, Illinois | Site Public Contact - (Research@carle.com) |
| Carle Physician Group-Mattoon/Charleston Mattoon, Illinois | Site Public Contact - (Research@carle.com) |
| Carle at The Riverfront Danville, Illinois | Site Public Contact - (Research@Carle.com) |
| Cedars-Sinai Medical Center Los Angeles, California | Site Public Contact - (Cancer.trial.info@cshs.org) |
| Centra Alan B Pearson Regional Cancer Center Lynchburg, Virginia | Site Public Contact - (Kevin.Patel@centrahealth.com) |
| Centralia Oncology Clinic Centralia, Illinois | Site Public Contact - (morganthaler.jodi@mhsil.com) |
| Chelsea Hospital Chelsea, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Clackamas Radiation Oncology Center Clackamas, Oregon | Site Public Contact - (CanRsrchStudies@providence.org) |
| Community Hospital of Anaconda Anaconda, Montana | Site Public Contact - (mccinfo@mtcancer.org) |
| Community Medical Center Toms River, New Jersey | Site Public Contact - (mccinfo@mtcancer.org) |
| Corewell Health Grand Rapids Hospitals - Butterworth Hospital Grand Rapids, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
| Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center Saint Joseph, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
| Corewell Health Lakeland Hospitals - Niles Hospital Niles, Michigan | |
| Corewell Health Reed City Hospital Reed City, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
| Crossroads Cancer Center Effingham, Illinois | Site Public Contact - (morganthaler.jodi@mhsil.com) |
| Dartmouth Cancer Center - North Saint Johnsbury, Vermont | Site Public Contact - (cancer.research.nurse@hitchcock.org) |
| Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center Lebanon, New Hampshire | Site Public Contact - (cancer.research.nurse@dartmouth.edu) |
| Decatur Memorial Hospital Decatur, Illinois | Site Public Contact - (morganthaler.jodi@mhsil.com) |
| Duluth Clinic Ashland Ashland, Wisconsin | Site Public Contact - (CancerTrials@EssentiaHealth.org) |
| Essentia Health - Deer River Clinic Deer River, Minnesota | Site Public Contact - (CancerTrials@EssentiaHealth.org) |
| Essentia Health - Fosston Fosston, Minnesota | Site Public Contact - (CancerTrials@EssentiaHealth.org) |
| Essentia Health - Jamestown Clinic Jamestown, North Dakota | Site Public Contact - (CancerTrials@EssentiaHealth.org) |
| Essentia Health - Park Rapids Park Rapids, Minnesota | Site Public Contact - (CancerTrials@EssentiaHealth.org) |
| Essentia Health Cancer Center Duluth, Minnesota | Site Public Contact - (CancerTrials@EssentiaHealth.org) |
| Essentia Health Cancer Center-South University Clinic Fargo, North Dakota | Site Public Contact - (CancerTrials@EssentiaHealth.org) |
| Essentia Health Hibbing Clinic Hibbing, Minnesota | |
| Essentia Health Saint Joseph's Medical Center Brainerd, Minnesota | Site Public Contact - (CancerTrials@EssentiaHealth.org) |
| Essentia Health Saint Mary's - Detroit Lakes Clinic Detroit Lakes, Minnesota | Site Public Contact - (CancerTrials@EssentiaHealth.org) |
| Essentia Health Saint Mary's Hospital - Superior Superior, Wisconsin | |
| Essentia Health Sandstone Sandstone, Minnesota | Site Public Contact - (CancerTrials@EssentiaHealth.org) |
| Essentia Health Virginia Clinic Virginia, Minnesota | Site Public Contact - (CancerTrials@EssentiaHealth.org) |
| Fairview Southdale Hospital Edina, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Genesee Hematology Oncology PC Flint, Michigan | |
| Genesys Hurley Cancer Institute Flint, Michigan | Site Public Contact - (wstrong@ghci.org) |
| Gundersen Lutheran Medical Center La Crosse, Wisconsin | Site Public Contact - (cancerctr@gundersenhealth.org) |
| Hawaii Cancer Care - Westridge ‘Aiea, Hawaii | |
| Hawaii Cancer Care Inc - Waterfront Plaza Honolulu, Hawaii | |
| Helen F Graham Cancer Center Newark, Delaware | Site Public Contact - (lbarone@christianacare.org) |
| Huntsman Cancer Institute/University of Utah Salt Lake City, Utah | Site Public Contact - (cancerinfo@hci.utah.edu) |
| Hurley Medical Center Flint, Michigan | Site Public Contact - (wstrong@ghci.org) |
| Huron Gastroenterology PC Ypsilanti, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Illinois CancerCare - Washington Washington, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Bloomington Bloomington, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Canton Canton, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Carthage Carthage, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Dixon Dixon, Illinois | |
| Illinois CancerCare-Eureka Eureka, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Galesburg Galesburg, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Kewanee Clinic Kewanee, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Macomb Macomb, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Ottawa Clinic Ottawa, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Pekin Pekin, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Peoria Peoria, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Peru Peru, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Princeton Princeton, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Inova Alexandria Hospital Alexandria, Virginia | Site Public Contact - (Stephanie.VanBebber@inova.org) |
| Inova Fair Oaks Hospital Fairfax, Virginia | Site Public Contact - (Stephanie.VanBebber@inova.org) |
| Inova Fairfax Hospital Falls Church, Virginia | Site Public Contact - (Stephanie.VanBebber@inova.org) |
| Inova Schar Cancer Institute Fairfax, Virginia | Site Public Contact - (Stephanie.VanBebber@inova.org) |
| Jefferson Torresdale Hospital Philadelphia, Pennsylvania | |
| Kootenai Clinic Cancer Services - Post Falls Post Falls, Idaho | Site Public Contact - (mccinfo@mtcancer.org) |
| Kootenai Clinic Cancer Services - Sandpoint Sandpoint, Idaho | Site Public Contact - (mccinfo@mtcancer.org) |
| Kootenai Health - Coeur d'Alene Coeur d'Alene, Idaho | Site Public Contact - (mccinfo@mtcancer.org) |
| Laura and Isaac Perlmutter Cancer Center at NYU Langone New York, New York | Site Public Contact - (CancerTrials@nyulangone.org) |
| Logan Health Medical Center Kalispell, Montana | Site Public Contact - (mccinfo@mtcancer.org) |
| Los Angeles General Medical Center Los Angeles, California | Site Public Contact - (uscnorrisinfo@med.usc.edu) |
| Loyola University Medical Center Maywood, Illinois | |
| Marshfield Medical Center - Minocqua Minocqua, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center - Weston Weston, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center-EC Cancer Center Eau Claire, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center-Marshfield Marshfield, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center-Rice Lake Rice Lake, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center-River Region at Stevens Point Stevens Point, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Mary Greeley Medical Center Ames, Iowa | |
| Mayo Clinic Hospital in Arizona Phoenix, Arizona | |
| Mayo Clinic in Florida Jacksonville, Florida | |
| Mayo Clinic in Rochester Rochester, Minnesota | |
| McFarland Clinic - Ames Ames, Iowa | Site Public Contact - (ksoder@mcfarlandclinic.com) |
| McFarland Clinic - Boone Boone, Iowa | |
| McFarland Clinic - Jefferson Jefferson, Iowa | |
| McFarland Clinic - Marshalltown Marshalltown, Iowa | |
| McFarland Clinic - Trinity Cancer Center Fort Dodge, Iowa | |
| Medical Center of the Rockies Loveland, Colorado | |
| Medical College of Wisconsin Milwaukee, Wisconsin | |
| Medical Oncology Hematology Consultants PA Newark, Delaware | Site Public Contact - (lbarone@christianacare.org) |
| Memorial Hospital East Shiloh, Illinois | Site Public Contact - (dschwab@wustl.edu) |
| Memorial Hospital North Colorado Springs, Colorado | |
| Mercy Cancer Center-West Lakes Clive, Iowa | |
| Mercy Hospital Coon Rapids, Minnesota | |
| Mercy Hospital Coon Rapids, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Mercy Hospital South St Louis, Missouri | Site Public Contact - (Danielle.Werle@mercy.net) |
| Mercy Medical Center - Des Moines Des Moines, Iowa | |
| Miami Valley Cancer Care and Infusion Greenville, Ohio | |
| Miami Valley Hospital North Dayton, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Miami Valley Hospital South Centerville, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Minnesota Oncology - Burnsville Burnsville, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Minnesota Oncology Hematology PA-Chaska Chaska, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Minnesota Oncology Hematology PA-Woodbury Woodbury, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Munson Medical Center Traverse City, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
| NYU Langone Hospital - Long Island Mineola, New York | Site Public Contact - (cancertrials@nyulangone.org) |
| Nebraska Medicine-Bellevue Bellevue, Nebraska | Site Public Contact - (unmcrsa@unmc.edu) |
| Nebraska Medicine-Village Pointe Omaha, Nebraska | |
| Northwell Health/Center for Advanced Medicine Lake Success, New York | |
| Northwestern Medicine Cancer Center Delnor Geneva, Illinois | Site Public Contact - (Donald.Smith3@nm.org) |
| Northwestern Medicine Cancer Center Kishwaukee DeKalb, Illinois | Site Public Contact - (Donald.Smith3@nm.org) |
| Northwestern Medicine Cancer Center Warrenville Warrenville, Illinois | Site Public Contact - (Donald.Smith3@nm.org) |
| Northwestern Medicine Glenview Outpatient Center Glenview, Illinois | |
| Northwestern Medicine Grayslake Outpatient Center Grayslake, Illinois | |
| Northwestern Medicine Lake Forest Hospital Lake Forest, Illinois | Site Public Contact - (cancertrials@northwestern.edu) |
| Northwestern Medicine Orland Park Orland Park, Illinois | Site Public Contact - (nctnprogram_rhlccc@northwestern.edu) |
| Northwestern University Chicago, Illinois | Site Public Contact - (cancer@northwestern.edu) |
| OSF Saint Francis Hospital and Medical Group Escanaba, Michigan | Site Public Contact - (WI_research_admin@hshs.org) |
| Oncology Associates at Mercy Medical Center Cedar Rapids, Iowa | |
| Park Nicollet Clinic - Saint Louis Park Saint Louis Park, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Poudre Valley Hospital Fort Collins, Colorado | |
| Premier Blood and Cancer Center Dayton, Ohio | |
| ProHealth D N Greenwald Center Mukwonago, Wisconsin | Site Public Contact - (research.institute@phci.org) |
| ProHealth Oconomowoc Memorial Hospital Oconomowoc, Wisconsin | |
| ProHealth Waukesha Memorial Hospital Waukesha, Wisconsin | |
| Providence Newberg Medical Center Newberg, Oregon | Site Public Contact - (CanRsrchStudies@providence.org) |
| Providence Portland Medical Center Portland, Oregon | Site Public Contact - (CanRsrchStudies@providence.org) |
| Providence Saint Vincent Medical Center Portland, Oregon | Site Public Contact - (CanRsrchStudies@providence.org) |
| Providence Willamette Falls Medical Center Oregon City, Oregon | Site Public Contact - (CanRsrchStudies@providence.org) |
| Queen's Cancer Cenrer - POB I Honolulu, Hawaii | |
| Queen's Cancer Center - Kuakini Honolulu, Hawaii | |
| Queen's Medical Center Honolulu, Hawaii | |
| Rapid City Regional Hospital Rapid City, South Dakota | Site Public Contact - (research@monument.health) |
| Regions Hospital Saint Paul, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Ridgeview Medical Center Waconia, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Rocky Mountain Regional VA Medical Center Aurora, Colorado | |
| Rush-Copley Healthcare Center Yorkville, Illinois | Site Public Contact - (Cancer.Research@rushcopley.com) |
| Rush-Copley Medical Center Aurora, Illinois | Site Public Contact - (RCMC_Cancer_Research@rush.edu) |
| Saint Alphonsus Cancer Care Center-Boise Boise, Idaho | Site Public Contact - (stephanie.couch@stjoeshealth.org) |
| Saint Alphonsus Cancer Care Center-Caldwell Caldwell, Idaho | Site Public Contact - (stephanie.couch@stjoeshealth.org) |
| Saint Alphonsus Cancer Care Center-Nampa Nampa, Idaho | Site Public Contact - (mccinfo@mtcancer.org) |
| Saint Alphonsus Cancer Care Center-Ontario Ontario, Oregon | Site Public Contact - (mccinfo@mtcancer.org) |
| Saint Charles Health System Bend, Oregon | Site Public Contact - (nosall@stcharleshealthcare.org) |
| Saint Francis Medical Center Cape Girardeau, Missouri | Site Public Contact - (sfmc@sfmc.net) |
| Saint John's Hospital - Healtheast Maplewood, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Saint Luke's Cancer Institute - Boise Boise, Idaho | Site Public Contact - (eslinget@slhs.org) |
| Saint Luke's Cancer Institute - Fruitland Fruitland, Idaho | Site Public Contact - (eslinget@slhs.org) |
| Saint Luke's Cancer Institute - Meridian Meridian, Idaho | Site Public Contact - (eslinget@slhs.org) |
| Saint Luke's Cancer Institute - Nampa Nampa, Idaho | Site Public Contact - (eslinget@slhs.org) |
| Saint Luke's Cancer Institute - Twin Falls Twin Falls, Idaho | Site Public Contact - (eslinget@slhs.org) |
| Saint Vincent Hospital Cancer Center Green Bay Green Bay, Wisconsin | Site Public Contact - (WI_research_admin@hshs.org) |
| Saint Vincent Hospital Cancer Center at Oconto Falls Oconto Falls, Wisconsin | Site Public Contact - (WI_research_admin@hshs.org) |
| Saint Vincent Hospital Cancer Center at Saint Mary's Green Bay, Wisconsin | Site Public Contact - (wi_research_admin@hshs.org) |
| Saint Vincent Hospital Cancer Center at Sheboygan Sheboygan, Wisconsin | Site Public Contact - (wi_research_admin@hshs.org) |
| Saint Vincent Hospital Cancer Center at Sturgeon Bay Sturgeon Bay, Wisconsin | Site Public Contact - (wi_research_admin@hshs.org) |
| Sanford Bismarck Medical Center Bismarck, North Dakota | Site Public Contact - (OncologyClinicalTrialsFargo@sanfordhealth.org) |
| Sanford Broadway Medical Center Fargo, North Dakota | Site Public Contact - (OncologyClinicalTrialsFargo@sanfordhealth.org) |
| Sanford Cancer Center Oncology Clinic Sioux Falls, South Dakota | Site Public Contact - (OncologyClinicTrialsSF@sanfordhealth.org) |
| Sanford Joe Lueken Cancer Center Bemidji, Minnesota | Site Public Contact - (OncologyClinicalTrialsFargo@sanfordhealth.org) |
| Sanford Roger Maris Cancer Center Fargo, North Dakota | Site Public Contact - (OncologyClinicalTrialsFargo@sanfordhealth.org) |
| Sanford USD Medical Center - Sioux Falls Sioux Falls, South Dakota | Site Public Contact - (OncologyClinicalTrialsSF@SanfordHealth.org) |
| Siteman Cancer Center at Christian Hospital St Louis, Missouri | Site Public Contact - (info@siteman.wustl.edu) |
| Siteman Cancer Center at Saint Peters Hospital City of Saint Peters, Missouri | Site Public Contact - (info@siteman.wustl.edu) |
| Siteman Cancer Center at West County Hospital Creve Coeur, Missouri | Site Public Contact - (info@siteman.wustl.edu) |
| Siteman Cancer Center-South County St Louis, Missouri | Site Public Contact - (info@siteman.wustl.edu) |
| Southeastern Medical Oncology Center-Clinton Clinton, North Carolina | Site Public Contact - (jfields@cancersmoc.com) |
| Southeastern Medical Oncology Center-Goldsboro Goldsboro, North Carolina | Site Public Contact - (jfields@cancersmoc.com) |
| Southeastern Medical Oncology Center-Jacksonville Jacksonville, North Carolina | Site Public Contact - (jfields@cancersmoc.com) |
| Southern Illinois University School of Medicine Springfield, Illinois | |
| Springfield Clinic Springfield, Illinois | |
| Springfield Memorial Hospital Springfield, Illinois | Site Public Contact - (pallante.beth@mhsil.com) |
| The Angeles Clinic and Research Institute - West Los Angeles Office Los Angeles, California | Site Public Contact - (protocols@swog.org) |
| Thomas Jefferson University Hospital Philadelphia, Pennsylvania | |
| Tower Cancer Research Foundation Beverly Hills, California | Site Public Contact - (towercancerresearch@toweroncology.com) |
| Trinity Health Grand Rapids Hospital Grand Rapids, Michigan | |
| Trinity Health IHA Medical Group Hematology Oncology - Brighton Brighton, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Trinity Health IHA Medical Group Hematology Oncology - Canton Canton, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital Chelsea, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus Ypsilanti, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Trinity Health Medical Center - Brighton Brighton, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Trinity Health Medical Center - Canton Canton, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Trinity Health Muskegon Hospital Muskegon, Michigan | |
| Trinity Health Saint Joseph Mercy Hospital Ann Arbor Ann Arbor, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Trinity Health Saint Joseph Mercy Oakland Hospital Pontiac, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Trinity Health Saint Mary Mercy Livonia Hospital Livonia, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Tufts Medical Center Boston, Massachusetts | |
| Tufts Medical Center Cancer Center Stoneham Stoneham, Massachusetts | |
| UC Irvine Health/Chao Family Comprehensive Cancer Center Orange, California | Site Public Contact - (ucstudy@uci.edu) |
| UCHealth Greeley Hospital Greeley, Colorado | Site Public Contact - (protocols@swog.org) |
| UCHealth Memorial Hospital Central Colorado Springs, Colorado | |
| UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care Irvine, California | Site Public Contact - (ucstudy@uci.edu) |
| UI Health Care Mission Cancer and Blood - Ankeny Clinic Ankeny, Iowa | |
| UI Health Care Mission Cancer and Blood - Des Moines Clinic Des Moines, Iowa | |
| UI Health Care Mission Cancer and Blood - Laurel Clinic Des Moines, Iowa | |
| UI Health Care Mission Cancer and Blood - Waukee Clinic Waukee, Iowa | |
| UI Health Care Mission Cancer and Blood - West Des Moines Clinic Clive, Iowa | |
| USC / Norris Comprehensive Cancer Center Los Angeles, California | |
| UW Cancer Center at ProHealth Care Waukesha, Wisconsin | Site Public Contact - (Chanda.miller@phci.org) |
| United Hospital Saint Paul, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Unity Hospital Fridley, Minnesota | |
| University of Arkansas for Medical Sciences Little Rock, Arkansas | |
| University of Illinois Chicago, Illinois | |
| University of Michigan Health - Sparrow Lansing Lansing, Michigan | Site Public Contact - (harsha.trivedi@umhsparrow.org) |
| University of Michigan Health - West Wyoming, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
| University of Michigan Rogel Cancer Center Ann Arbor, Michigan | Site Public Contact - (CancerAnswerLine@med.umich.edu) |
| University of Nebraska Medical Center Omaha, Nebraska | Site Public Contact - (unmcrsa@unmc.edu) |
| University of New Mexico Cancer Center Albuquerque, New Mexico | Site Public Contact - (HSC-ClinicalTrialInfo@salud.unm.edu) |
| University of Oklahoma Health Sciences Center Oklahoma City, Oklahoma | Site Public Contact - (ou-clinical-trials@ouhsc.edu) |
| Upper Valley Medical Center Troy, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| VCU Health Tappahannock Hospital Tappahannock, Virginia | Site Public Contact - (klcampbell@vcu.edu) |
| VCU Massey Cancer Center at Stony Point Richmond, Virginia | Site Public Contact - (ctoclinops@vcu.edu) |
| VCU Massey Comprehensive Cancer Center Richmond, Virginia | Site Public Contact - (CTOclinops@vcu.edu) |
| Virginia Cancer Institute Richmond, Virginia | Site Public Contact - (smoore@vacancer.com) |
| Washington University School of Medicine St Louis, Missouri | Site Public Contact - (info@siteman.wustl.edu) |
| Wayne State University/Karmanos Cancer Institute Detroit, Michigan | |
| Weisberg Cancer Treatment Center Farmington Hills, Michigan | |
| West Michigan Cancer Center Kalamazoo, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
Neutrophil and Monocyte Deactivation Via the SeLective CytopheretIc Device - A Randomized Clinical Trial in Acute Kidney Injury (NEUTRALIZE-AKI)
Mohamed Zidan, MD - mzidan@seastarmed.com
NCT05758077
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Inclusion Criteria:
* Admitted to an ICU requiring CKRT:
• Must have AKI stage 2 or greater at the time of CKRT initiation.
• Must have been on CKRT for at least 12 hours but no greater than 48 hours at the time of enrollment. * At least 18 years of age but not older than 80 at the time of enrollment. * One additional life-threatening organ dysfunction present. * Acceptable vascular access for CKRT to include adequate lumen size and length of catheters. * Initial (non-binding) commitment to maintaining current level of care for at least 96 hours. * C-Reactive Protein \>3.5 mg/dl.
Exclusion Criteria:
* Not expected to survive next 24 hours.
* Anticipated transition to comfort measures or hospice in next 4 days.
* Terminal condition whereby the patient is not expected to survive 28 days or any condition in which therapy is regarded as futile by the PI.
* Advanced malignancy which is actively being treated or may be treated with palliative chemotherapy or radiation.
* ICU hospitalization \> 14 days during this hospital admission (to include days spent at ICU of an outside hospital) at the time of screening.
* Active COVID-19 infection with a primary admission diagnosis of COVID-19.
* Chronic use of ventricular assist devices.
* ESRD requiring chronic kidney replacement therapy.
* History of CKD (greater than Stage 3).
* AKI stage 0 or stage 1 at the time of CKRT initiation.
* Non-ATN AKI diagnosis. We intend on relying on local nephrology subspecialty expertise to reasonably exclude non-ATN diagnoses based on clinical suspicions combined with prespecified objective criteria. If there is a reasonable suspicion that the subject has non-ATN AKI based on this, they will be excluded from the trial.
* Acute coronary syndromes, acute stroke, or acute major vascular compromise requiring medical or surgical interventions within 48 hours of randomization.
* Active hemorrhage requiring blood transfusions at the time of screening.
* Acute on Chronic Liver Failure.
* Suspicion of hepato-renal syndrome.
* Presence of any solid organ transplant at any time prior to admission.
* Severe burns with a modified Baux score \> 100 (%TBSA+Age+17 for Inhalation Injury).
* Bone marrow transplant within the last year.
* Chronic immunosuppression with an average of \>20 mg/day of prednisone or other steroid sparing immunosuppressants for the past 30 days prior to hospital admission.
* Individuals who have a history of primary or secondary immune disorders including, but not limited to, HIV or AIDS.
* Dry weight of \>150kg.
* Platelet count \<15,000/mm3.
* Patient is a prisoner or member of a vulnerable population.
* Patient is pregnant or breast feeding.
* Concurrent enrollment in another interventional clinical trial for an investigational drug or device.
* Need for plasmapheresis. DEVICE: Selective Cytopheretic Device, OTHER: Standard of Care
Acute Kidney Injury
continuous kidney replacement therapy, continuous renal replacement therapy, acute kidney injury, organ failure, inflammation, dialysis, acute tubular necrosis
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See this study on ClinicalTrials.gov
Show 38 locations
Study Locations
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| Location | Contacts |
|---|---|
| AdventHealth Orlando Orlando, Florida | |
| Brooke Army Medical Center San Antonio, Texas | |
| Cleveland Clinic Cleveland, Ohio | |
| Emory HealthCare Atlanta, Georgia | |
| Geisinger Wyoming Valley Medical Center Wilkes-Barre, Pennsylvania | |
| Henry Ford Medical Center Sterling Heights, Michigan | |
| JMS Burn Center Augusta, Georgia | |
| Mayo Clinic Rochester, Minnesota | |
| Mayo Clinic in Arizona Scottsdale, Arizona | |
| Mayo Clinic in Florida Jacksonville, Florida | |
| Medical University of South Carolina Charleston, South Carolina | |
| Methodist Hospital Memphis, Tennessee | |
| Methodist Hospital Metropolitan San Antonio, Texas | |
| Nazareth Hospital Philadelphia, Pennsylvania | |
| Northeast Georgia Health System Gainesville, Georgia | |
| Ochsner LSU Health Academic Medical Center Shreveport, Louisiana | |
| Orlando Regional Medical Center Orlando, Florida | |
| Ronald Reagan UCLA Medical Center Los Angeles, California | |
| Saint Mary Medical Center Hobart, Indiana | |
| Samaritan Health Corvallis, Oregon | |
| Sentara Health Norfolk, Virginia | |
| St Luke's University Hospital Bethlehem, Pennsylvania | |
| Stanford University Stanford, California | |
| The Ohio State University Wexner Medical Center Columbus, Ohio | |
| UNLV Health Las Vegas, Nevada | |
| United States Army Institute of Surgical Research JBSA Fort Sam Houston, Texas | |
| University of Alabama Birmingham Hospital Birmingham, Alabama | |
| University of California San Francisco San Francisco, California | |
| University of Cincinnati Cincinnati, Ohio | |
| University of Colorado Hospital Anschutz Medical Campus Aurora, Colorado | |
| University of Iowa Hospital Iowa City, Iowa | |
| University of Kentucky Healthcare Lexington, Kentucky | |
| University of Maryland Medical Center Baltimore, Maryland | |
| University of Michigan Ann Arbor, Michigan | |
| University of North Carolina Chapel Hill, North Carolina | |
| University of Texas Health San Antonio San Antonio, Texas | |
| University of Texas Southwestern Medical Center Dallas, Texas | |
| Virginia Commonwealth University Richmond, Virginia |
Remote Monitoring and Management of Chemotherapy Induced Peripheral Neuropathy (REMOTE-CIPN)
Noah A Kolb, MD - noah.kolb@uvmhealth.org
NCT04763356
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Inclusion Criteria:
In order to be eligible to participate in this study, an individual must meet all of the following criteria:
• Age ≥ 18.
• Completion of taxane, platinum, vinca alkaloid-based chemotherapy, bortezomib, thalidomide, lenalidomide, ixazomib, or brentuximab vedotin for cancer in the last 540 days, or ongoing maintenance therapy with bortezomib, thalidomide, lenalidomide or ixazomib for \> 90 days or ongoing survival, palliative or equivalent therapy with any of the above listed drugs for \>90 days.
• Development of CIPN during or within 3 months of the most recently completed chemotherapy or previous neurotoxic chemotherapy for the same malignancy. For patients on ongoing maintenance therapy: Development of CIPN during current neurotoxic chemotherapy with bortezomib, thalidomide, lenalidomide, ixazomib brentuximab vendotin or vincristine. CIPN diagnosis will be based on clinical diagnosis and the Toronto Criteria for Probable Distal Symmetric Polyneuropathy including the upper and lower extremities. The Toronto Criteria for Probable Distal Symmetric Polyneuropathy is defined as a combination of symptoms and signs of neuropathy including:
• At least 1 (one) of the following neuropathic symptoms: "asleep numbness", prickling or stabbing, burning or aching pain AND
• At least 1 (one) of the following: decreased distal sensation, or unequivocally decreased or absent ankle reflexes. (59) Clinical Diagnosis: a. Confirmation of CIPN diagnosis by CIPN expert (investigator/co-infestigator based on chart review +/- inperson/virtual interview with examination).
• Presence of at least one positive neuropathic sensory symptom on the NTSS-6 ranked as moderate or severe on the day of screening or in the preceding week based on recall.
• The ability to speak/ read sufficient English to be able to communicate with study NP over the phone, utilize the App, website and phone tree (all of which are only available in English).
Exclusion Criteria:
An individual who meets any of the following criteria will be excluded from participation in this study:
• Expected treatment with another neurotoxic chemotherapy within the 13 week overall study duration (For example, platinum, taxane, vinca alkaloid, thalidomide, brentuximab vedotin or related drug, or arsenic trioxide. This exclusion does not apply to continuation of treatment for patients on maintenance therapy as described in the inclusion criteria).
• Presence of a neurological problem that would confound CIPN assessment (lumbar or cervical radiculopathy, or pre-existing neuropathy from another cause such as diabetes).
• Currently receiving treatment at a pain clinic specifically for CIPN pain.
• Concurrent participation in a different CIPN or pain treatment trial.
• For women of childbearing potential: Current pregnancy
• For women of childbearing potential: Unwillingness to use and acceptable form of birth control for the duration of the study. Acceptable forms of birth control include long acting implantable contraception (ie IUDs, Nexplanon), Oral contraception pills, contraception injections, or strict abstinence if it is part of the subject's current lifestyle.
OTHER: Symptom Care at Home with NP follow up
Chemotherapy-induced Peripheral Neuropathy
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Study Locations
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| Location | Contacts |
|---|---|
| University of Utah Salt Lake City, Utah | Samantha Stebleton - (samantha.stebleton@nurs.utah.edu) Christina Echeverria, MA - (christina.echeverria@nurs.utah.edu) |
| University of Vermont Burlington, Vermont | Hannah Taylor, BA - (hannah.taylor@uvmhealth.org) Mary Healey, BA - (mary.healey@uvmhealth.org) |
| Virginia Commonwealth University Massey Cancer Center Richmond, Virginia | Melanie Crabtree - (crabtreemb@vcu.edu) Tyler Phillips - (phillipst5@vcu.edu) |
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease (CIRCULATE-US)
Judy Langer - langerj@nrgoncology.org
NCT05174169
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Inclusion Criteria:
The patient must have an ECOG performance status of 0 or 1.
Patients must have histologically/pathologically confirmed Stage IIB, IIC, or Stage III colon adenocarcinoma with R0 resection according to AJCC 8th edition criteria.
No radiographic evidence of overt metastatic disease within 45 days prior to Step 1/Study entry (CT with IV contrast or MRI imaging is acceptable and must include chest, abdomen, and pelvis).
The distal extent of the tumor must be greater than or equal to 12 cm from the anal verge on colonoscopy or above the peritoneal reflection as documented during surgery or on pathology specimen (i.e., excluding rectal adenocarcinomas warranting treatment with chemoradiation).
The patient must have had an en bloc complete gross resection of tumor (curative resection). Patients who have had a two-stage surgical procedure, to first provide a decompressive colostomy and then in a later procedure to have the definitive surgical resection, are eligible.
The resected tumor specimen and a blood specimen from patients with Stage IIB, IIC, or Stage III colon cancer must have central testing for ctDNA using the Signatera™ assay by Natera (after Step 1/Study entry and before Step2/Randomization). Patient must have sufficient tissue to meet protocol requirements. This blood specimen for the Signatera assay must be collected after surgery (and recommended at least 14 days post surgery).
Tumor must be documented as microsatellite stable or have intact mismatch repair proteins through CLIA-approved laboratory testing. Patients whose tumors are MSI-H or dMMR are excluded.
The treating investigator must deem the patient a candidate for all potential agents used in this trial (5FU, LV, oxaliplatin and irinotecan).
The interval between surgery (post-operative Day 7) and Step 1/Study entry must be no more than 60 days. NOTE: Step 1/Study Entry may occur as early as post operative Day 7, but it cannot occur beyond 60 days from the actual date of the patient's surgery.
Availability and provision of adequate surgical tumor tissue for molecular diagnostics and confirmatory profiling.
Adequate hematologic function within 28 days before Step 1/Study entry defined as follows:
* Absolute neutrophil count (ANC) must be greater than or equal to 1500/mm3;
* Participants with benign ethnic neutropenia (BEN): ANC less than 1300 mm3 are eligible.
* BEN (also known as constitutional neutropenia) is an inherited cause of mild or moderate neutropenia that is not associated with any increased risk for infections or other clinical manifestations. BEN is referred to as ethnic neutropenia because of its increased prevalence in people of African descent and other specific ethnic groups.
* Platelet count must be greater than or equal to 100,000/mm3; and
* Hemoglobin must be greater than or equal to 9 g/dL.
Adequate hepatic function within 28 days before Step 1/Study entry defined as follows:
* total bilirubin must be less than or equal to ULN (upper limit of normal) for the lab and
* alkaline phosphatase must be less than 2.5 x ULN for the lab; and
* AST and ALT must be less than 2.5 x ULN for the lab.
Adequate renal function within 28 days before Step 1/Study entry defined as serum creatinine less than or equal to 1.5 x ULN for the lab or measured or calculated creatinine clearance greater than or equal to 50 mL/min using the Cockroft-Gault formula for patients with creatinine levels greater than 1.5 x ULN for the lab.
For Women Creatinine Clearance (mL/min) = (140 - age) x weight (kg) x 0.85 72 x serum creatinine (mg/dL) For Men Creatinine Clearance (mL/min) = (140 - age) x weight (kg) 72 x serum creatinine (mg/dL) NOTE: Adjusted body weight (AdjBW) should be used for patients that have BMI greater than or equal to 28 (less than or equal to 30% above IBW).
HIV-infected patients on effective anti-retroviral therapy with undetectable viral load within 6 months are eligible for this trial.
Pregnancy test (urine or serum according to institutional standard) done within 14 days before Step 1/Study entry must be negative (for women of childbearing potential only).
Patients receiving a coumarin-derivative anticoagulant must agree to weekly monitoring of INR if they are randomized to Arm 1 or Arm 3 and receive capecitabine.
Eligibility Criteria for Cohort A Arm-2 patients on Second Randomization
Patient must have developed a ctDNA +ve assay during serial monitoring.
Patient's willingness to be re-randomized affirmed.
The patient must continue to have an ECOG performance status of 0 or 1.
No radiographic evidence of overt metastatic disease.
Pregnancy test (urine or serum according to institutional standard) done within 14 days before second randomization must be negative (for women of childbearing potential only).
Adequate hematologic function within 28 days before second randomization defined as follows:
* Absolute neutrophil count (ANC) must be greater than or equal to 1500/mm3;
* Participants with benign ethnic neutropenia (BEN): ANC less than 1300 mm3 are eligible.
* BEN (also known as constitutional neutropenia) is an inherited cause of mild or moderate neutropenia that is not associated with any increased risk for infections or other clinical manifestations. BEN is referred to as ethnic neutropenia because of its increased prevalence in people of African descent and other specific ethnic groups.
* Platelet count must be greater than or equal to 100,000/mm3; and
* Hemoglobin must be greater than or equal to 9 g/dL.
Adequate hepatic function within 28 days before second randomization defined as follows:
* total bilirubin must be less than or equal to ULN (upper limit of normal) for the lab and
* alkaline phosphatase must be less than 2.5 x ULN for the lab; and
* AST and ALT must be less than 2.5 x ULN for the lab.
Adequate renal function within 28 days before second randomization defined as serum creatinine less than or equal to 1.5 x ULN for the lab or measured or calculated creatinine clearance greater than or equal to 50 mL/min using the Cockroft-Gault formula for patients with creatinine levels greater than 1.5 x ULN for the lab.
For Women Creatinine Clearance (mL/min) = (140 - age) x weight (kg) x 0.85 72 x serum creatinine (mg/dL) For Men Creatinine Clearance (mL/min) = (140 - age) x weight (kg) 72 x serum creatinine (mg/dL)
Exclusion Criteria:
Colon cancer histology other than adenocarcinoma (i.e., neuroendocrine carcinoma, sarcoma, lymphoma, squamous cell carcinoma, etc.).
Pathologic, clinical, or radiologic overt evidence of metastatic disease. This includes isolated, distant, or non-contiguous intra-abdominal metastases, even if resected.
Tumor-related bowel perforation.
History of prior invasive colon malignancy, regardless of disease-free interval.
History of bone marrow or solid organ transplantation (regardless of current immunosuppressive therapy needs). Bone grafts, skin grafts, corneal transplants and organ/tissue donation are not exclusionary.
Any prior systemic chemotherapy, targeted therapy, or immunotherapy; or radiation therapy administered as treatment for colorectal cancer (e.g., primary colon adenocarcinomas for which treatment with neoadjuvant chemotherapy and/or radiation is warranted are not permitted). EXCEPTION: one cycle of chemotherapy (regimen per treating physicians' discretion - 5-FU or capecitabine with or without oxaliplatin) is allowed but not required after consent. The optional cycle of chemotherapy should be started greater than or equal to 4 weeks from surgery and while awaiting Step 2 randomization.
Other invasive malignancy within 5 years before Step 1/Study entry. Exceptions are colonic polyps, non-melanoma skin cancer or any carcinoma-in-situ.
Synchronous primary rectal and/ or colon cancers.
Patients with known history or current symptoms of cardiac disease, or history of treatment with cardiotoxic agents, should have a clinical risk assessment of cardiac function using the New York Heart Association Functional Classification. To be eligible for this trial, patients should be class 2B or better.
Sensory or motor neuropathy greater than or equal to grade 2, according to CTCAE v5.0.
Blood transfusion within two weeks before collection of blood for central ctDNA testing.
Active seizure disorder uncontrolled by medication.
Active or chronic infection requiring systemic therapy.
Known homozygous DPD (dihydropyrimidine dehydrogenase) deficiency.
Patients known to have Gilbert's Syndrome or homozygosity for UGT1A1\*28 polymorphism.
Pregnancy or lactation at the time of Step 1/Study entry.
Co-morbid illnesses or other concurrent disease that would make the patient inappropriate for entry into this study (i.e., unable to tolerate 6 months of combination chemotherapy or interfere significantly with the proper assessment of safety and toxicity of the prescribed regimens or prevent required follow-up).
Ineligibility Criteria for Cohort A Arm-2 patients on Second Randomization
Pregnancy or lactation at the time of randomization.
No longer a candidate for systemic chemotherapy (FOLFOX, CAPOX, and mFOLFIRINOX) in the opinion of the treating investigator. DEVICE: Signatera test, DRUG: mFOLFOX6 3-6 month, DRUG: CAPOX 3 month, DRUG: mFOLFIRINOX, DRUG: mFOLFOX6 6 month, DRUG: CAPOX 6 month
Stage III Colon Cancer
ctDNA positive, ctDNA negative, Adjuvant Chemotherapy, Natera, Signatera, mFOLFOX6, Stage III, CAPOX, mFOLFIRINOX, Oxaliplatin, 5-Fluorouracil (5-FU), Capecitabine, Leucovorin, Irinotecan, Stage II
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Show 1077 locations
Study Locations
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| Location | Contacts |
|---|---|
| AIS Cancer Center at San Joaquin Community Hospital Bakersfield, California | |
| AMG Crystal Lake - Oncology Crystal Lake, Illinois | Site Public Contact - (advocateresearch@advocate.com) |
| AMG Libertyville - Oncology Libertyville, Illinois | Site Public Contact - (advocateresearch@advocatehealth.com) |
| Abbeville General Hospital Abbeville, Louisiana | |
| Abbott-Northwestern Hospital Minneapolis, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Adams Cancer Center Gettysburg, Pennsylvania | |
| Addison Gilbert Hospital Gloucester, Massachusetts | |
| Adena Regional Medical Center Chillicothe, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Advanced Breast Care Center PLLC Warren, Michigan | |
| AdventHealth Altamonte Altamonte Springs, Florida | |
| AdventHealth Celebration Celebration, Florida | |
| AdventHealth East Orlando Orlando, Florida | |
| AdventHealth Kissimmee Kissimmee, Florida | |
| AdventHealth Littleton Littleton, Colorado | |
| AdventHealth Orlando Orlando, Florida | Site Public Contact - (FH.Cancer.Research@flhosp.org) |
| AdventHealth Parker Parker, Colorado | |
| AdventHealth Porter Denver, Colorado | |
| AdventHealth Winter Park Winter Park, Florida | |
| Advocate Christ Medical Center Oak Lawn, Illinois | |
| Advocate Good Samaritan Hospital Downers Grove, Illinois | Site Public Contact - (Barbara.barhamand@advocatehealth.com) |
| Advocate Good Shepherd Hospital Barrington, Illinois | |
| Advocate Illinois Masonic Medical Center Chicago, Illinois | |
| Advocate Lutheran General Hospital Park Ridge, Illinois | |
| Advocate Outpatient Center - Aurora Aurora, Illinois | Site Public Contact - (ncorp@aah.org) |
| Advocate Sherman Hospital Elgin, Illinois | |
| Advocate South Suburban Hospital Hazel Crest, Illinois | |
| Alegent Health Bergan Mercy Medical Center Omaha, Nebraska | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Alegent Health Immanuel Medical Center Omaha, Nebraska | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Alegent Health Lakeside Hospital Omaha, Nebraska | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Alegent Health Mercy Hospital Council Bluffs, Iowa | |
| Allan Blair Cancer Centre Regina, Saskatchewan | |
| Allegheny General Hospital Pittsburgh, Pennsylvania | |
| Allegheny Valley Hospital Natrona Heights, Pennsylvania | Site Public Contact - (Dawnmarie.DeFazio@ahn.org) |
| Alta Bates Summit Medical Center-Herrick Campus Berkeley, California | Site Public Contact - (clinicalresearch@sutterhealth.org) |
| Altru Cancer Center Grand Forks, North Dakota | |
| American Fork Hospital / Huntsman Intermountain Cancer Center American Fork, Utah | Site Public Contact - (officeofresearch@imail.org) |
| Armes Family Cancer Center Findlay, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Arnold Palmer Cancer Center Medical Oncology Norwin N. Huntingdon, Pennsylvania | Site Public Contact - (ClinicalResearchServices@upmc.edu) |
| Arthur J E Child Comprehensive Cancer Centre Calgary, Alberta | Site Public Contact - (Roster@nrgoncology.org) |
| Ascension All Saints Hospital-Spring Street-Racine Racine, Wisconsin | Site Public Contact - (AWRI.Inquiry@Ascension.org) |
| Ascension Calumet Hospital-Chilton Chilton, Wisconsin | Site Public Contact - (AWRI.inquiry@ascension.org) |
| Ascension Columbia Saint Mary's Hospital-Milwaukee Campus Milwaukee, Wisconsin | Site Public Contact - (AWRI.Inquiry@Ascension.org) |
| Ascension Columbia Saint Mary's Hospital-Ozaukee Campus-Mequon Mequon, Wisconsin | Site Public Contact - (AWRI.Inquiry@Ascension.org) |
| Ascension Northeast Wisconsin-Mercy Hospital-Oshkosh Oshkosh, Wisconsin | Site Public Contact - (AWRI.inquiry@ascension.org) |
| Ascension Northeast Wisconsin-Saint Elizabeth Cancer Center-Appleton Appleton, Wisconsin | Site Public Contact - (AWRI.inquiry@ascension.org) |
| Ascension Southeast Wisconsin Hospital-Elmbrook Campus-Brookfield Brookfield, Wisconsin | Site Public Contact - (AWRI.Inquiry@Ascension.org) |
| Ascension Southeast Wisconsin Hospital-Mayfair Road-Wauwatosa Wauwatosa, Wisconsin | Site Public Contact - (AWRI.Inquiry@Ascension.org) |
| Ascension Via Christi Hospitals Wichita Wichita, Kansas | Site Public Contact - (research@viachristi.org) |
| Aspirus Cancer Care - Stevens Point Stevens Point, Wisconsin | Site Public Contact - (Beth.Knetter@aspirus.org) |
| Aspirus Cancer Care - Wisconsin Rapids Wisconsin Rapids, Wisconsin | |
| Aspirus Cancer Care-Antigo-Volm Cancer Center Antigo, Wisconsin | Site Public Contact - (Juli.Alford@aspirus.org) |
| Aspirus Cancer Care-Rhinelander-James Beck Cancer Center Rhinelander, Wisconsin | Site Public Contact - (Beth.Knetter@aspirus.org) |
| Aspirus Cancer Care-Wausau Wausau, Wisconsin | |
| Aspirus Medford Hospital Medford, Wisconsin | Site Public Contact - (Beth.Knetter@aspirus.org) |
| Asplundh Cancer Pavilion Willow Grove, Pennsylvania | Site Public Contact - (ONCTrialNow@jefferson.edu) |
| AtlantiCare Health Park-Cape May Court House Cape May Court House, New Jersey | |
| AtlantiCare Surgery Center Egg Harbor, New Jersey | |
| Atlantic Health Sciences Corporation-Saint John Regional Hospital Saint John, New Brunswick | |
| Atrium Health Cabarrus/LCI-Concord Concord, North Carolina | |
| Atrium Health Pineville/LCI-Pineville Charlotte, North Carolina | |
| Atrium Health Union/LCI-Union Monroe, North Carolina | |
| Atrium Health University City/LCI-University Charlotte, North Carolina | |
| Atrium Medical Center-Middletown Regional Hospital Franklin, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Aultman Alliance Community Hospital Alliance, Ohio | |
| Aultman Health Foundation Canton, Ohio | Site Public Contact - (ClinicalReserachDept@aultman.com) |
| Aurora Bay Area Medical Group-Marinette Marinette, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora BayCare Medical Center Green Bay, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Cancer Care-Grafton Grafton, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Cancer Care-Kenosha South Kenosha, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Cancer Care-Milwaukee Milwaukee, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Cancer Care-Milwaukee West Wauwatosa, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Cancer Care-Racine Racine, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Cancer Care-Southern Lakes VLCC Burlington, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Health Care Germantown Health Center Germantown, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Medical Center in Summit Summit, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Saint Luke's Medical Center Milwaukee, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Saint Luke's South Shore Cudahy, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Sinai Medical Center Milwaukee, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora West Allis Medical Center West Allis, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Avera Cancer Institute Sioux Falls, South Dakota | Site Public Contact - (OncRegulatory@avera.org) |
| Avera Cancer Institute - Mitchell Mitchell, South Dakota | Site Public Contact - (OncRegulatory@avera.org) |
| Avera Cancer Institute at Pierre Pierre, South Dakota | Site Public Contact - (OncRegulatory@avera.org) |
| Avera Cancer Institute at Yankton Yankton, South Dakota | Site Public Contact - (OncRegulatory@avera.org) |
| Avera Cancer Institute-Aberdeen Aberdeen, South Dakota | Site Public Contact - (oncregulatory@avera.org) |
| BASS Medical Group - Lennon Walnut Creek, California | |
| BCCA-Cancer Centre for the North Prince George, British Columbia | |
| BCCA-Vancouver Cancer Centre Vancouver, British Columbia | |
| BCCA-Vancouver Island Cancer Centre Victoria, British Columbia | |
| Banner University Medical Center - Tucson Tucson, Arizona | Site Public Contact - (UACC-IIT@uacc.arizona.edu) |
| Baptist Cancer Center-Grenada Grenada, Mississippi | Site Public Contact - (BCCclintrials@bmhcc.org) |
| Baptist Health Hamburg Lexington, Kentucky | |
| Baptist Health Lexington Lexington, Kentucky | |
| Baptist MD Anderson Cancer Center Jacksonville, Florida | |
| Baptist Memorial Hospital and Cancer Center-Collierville Collierville, Tennessee | Site Public Contact - (BCCclintrials@bmhcc.org) |
| Baptist Memorial Hospital and Cancer Center-Desoto Southhaven, Mississippi | Site Public Contact - (BCCclintrials@bmhcc.org) |
| Baptist Memorial Hospital and Cancer Center-Golden Triangle Columbus, Mississippi | Site Public Contact - (BCCclintrials@bmhcc.org) |
| Baptist Memorial Hospital and Cancer Center-Memphis Memphis, Tennessee | Site Public Contact - (BCCclintrials@bmhcc.org) |
| Baptist Memorial Hospital and Cancer Center-Oxford Oxford, Mississippi | Site Public Contact - (BCCclintrials@bmhcc.org) |
| Baptist Memorial Hospital and Cancer Center-Union County New Albany, Mississippi | Site Public Contact - (BCCclintrials@bmhcc.org) |
| Bay Area Tumor Institute Oakland, California | |
| Bayhealth Hospital Kent Campus Dover, Delaware | |
| Bayhealth Hospital Sussex Campus Milford, Delaware | |
| Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center Houston, Texas | Site Public Contact - (burton@bcm.edu) |
| Beacon Kalamazoo Cancer Center Kalamazoo, Michigan | |
| Bellin Memorial Hospital Green Bay, Wisconsin | |
| Ben Taub General Hospital Houston, Texas | |
| Benefis Sletten Cancer Institute Great Falls, Montana | Site Public Contact - (mccinfo@mtcancer.org) |
| Beth Israel Deaconess Medical Center/Winchester Center for Cancer Care Winchester, Massachusetts | |
| Bethesda North Hospital Cincinnati, Ohio | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Beverly Hospital Beverly, Massachusetts | |
| Bhadresh Nayak MD PC-Sterling Heights Sterling Heights, Michigan | |
| Billings Clinic Cancer Center Billings, Montana | Site Public Contact - (research@billingsclinic.org) |
| Blanchard Valley Hospital Findlay, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Bon Secours Memorial Regional Medical Center Mechanicsville, Virginia | Site Public Contact - (anne_carmellat@bshsi.org) |
| Bon Secours Richmond Community Hospital Richmond, Virginia | Site Public Contact - (anne_carmellat@bshsi.org) |
| Bon Secours Saint Francis Hospital Charleston, South Carolina | |
| Bon Secours Saint Francis Medical Center Midlothian, Virginia | Site Public Contact - (anne_carmellat@bshsi.org) |
| Bon Secours Saint Mary's Hospital Richmond, Virginia | Site Public Contact - (anne_carmellat@bshsi.org) |
| Boston Medical Center Boston, Massachusetts | |
| Bozeman Health Deaconess Hospital Bozeman, Montana | Site Public Contact - (mccinfo@mtcancer.org) |
| Bronson Battle Creek Battle Creek, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
| Bronson Methodist Hospital Kalamazoo, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
| CHI Health Good Samaritan Kearney, Nebraska | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| CHI Saint Vincent Cancer Center Hot Springs Hot Springs, Arkansas | |
| CHU de Quebec-L'Hotel-Dieu de Quebec (HDQ) Québec, Quebec | Site Public Contact - (rechclinique@crchuq.ulaval.ca) |
| CIUSSSEMTL-Hopital Maisonneuve-Rosemont Montreal, Quebec | |
| CSSS Champlain-Charles Le Moyne Greenfield Park, Quebec | |
| CTCA at Southeastern Regional Medical Center Newnan, Georgia | |
| California Pacific Medical Center-Pacific Campus San Francisco, California | Site Public Contact - (clinicalresearch@sutterhealth.org) |
| Cambridge Medical Center Cambridge, Minnesota | |
| Cambridge Memorial Hospital Cambridge, Ontario | |
| Camden Clark Medical Center Parkersburg, West Virginia | Site Public Contact - (cancertrialsinfo@hsc.wvu.edu) |
| Cancer Care Associates of York York, Pennsylvania | |
| Cancer Care Center of O'Fallon O'Fallon, Illinois | Site Public Contact - (morganthaler.jodi@mhsil.com) |
| Cancer Care Specialists of Illinois - Decatur Decatur, Illinois | Site Public Contact - (morganthaler.jodi@mhsil.com) |
| Cancer Care and Hematology-Fort Collins Fort Collins, Colorado | Site Public Contact - (Roster@nrgoncology.org) |
| Cancer Center at Saint Joseph's Phoenix, Arizona | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Cancer Center of Kansas-Wichita Medical Arts Tower Wichita, Kansas | Site Public Contact - (research@viachristi.org) |
| Cancer Center of Western Wisconsin New Richmond, Wisconsin | Site Public Contact - (mmcorc@healthpartners.com) |
| Cancer Centers of Southwest Oklahoma Research Lawton, Oklahoma | |
| Cancer Hematology Centers - Flint Flint, Michigan | Site Public Contact - (wstrong@ghci.org) |
| Cancer Partners of Nebraska Lincoln, Nebraska | Site Public Contact - (research@cancerpartners.com) |
| Cancer Specialists of Tidewater Limited Chesapeake, Virginia | Site Public Contact - (casey.morris@rivhs.com) |
| Cancer Specialists of Tidewater-Suffolk Suffolk, Virginia | Site Public Contact - (casey.morris@rivhs.com) |
| Cancer and Hematology Centers of Western Michigan - Norton Shores Norton Shores, Michigan | |
| Carle Cancer Center Urbana, Illinois | Site Public Contact - (Research@carle.com) |
| Carle Physician Group-Effingham Effingham, Illinois | Site Public Contact - (Research@carle.com) |
| Carle Physician Group-Mattoon/Charleston Mattoon, Illinois | Site Public Contact - (Research@carle.com) |
| Carle at The Riverfront Danville, Illinois | Site Public Contact - (Research@Carle.com) |
| Carlisle Regional Cancer Center Carlisle, Pennsylvania | Site Public Contact - (Roster@nrgoncology.org) |
| Caro Cancer Center Caro, Michigan | |
| CaroMont Regional Medical Center Gastonia, North Carolina | Site Public Contact - (tammy.cozad@caromonthealth.org) |
| Carolinas Medical Center/Levine Cancer Institute Charlotte, North Carolina | |
| Carson Tahoe Regional Medical Center Carson City, Nevada | Site Public Contact - (research@sncrf.org) |
| Case Western Reserve University Cleveland, Ohio | |
| Cedars-Sinai Medical Center Los Angeles, California | Site Public Contact - (Cancer.trial.info@cshs.org) |
| Centra Alan B Pearson Regional Cancer Center Lynchburg, Virginia | Site Public Contact - (Kevin.Patel@centrahealth.com) |
| Central Care Cancer Center - Bolivar Bolivar, Missouri | Site Public Contact - (aroland@kccop.org) |
| Central Care Cancer Center - Garden City Garden City, Kansas | Site Public Contact - (aroland@kccop.org) |
| Central Care Cancer Center - Great Bend Great Bend, Kansas | Site Public Contact - (aroland@kccop.org) |
| Central Ohio Breast and Endocrine Surgery Gahanna, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Central Vermont Medical Center/National Life Cancer Treatment Berlin Corners, Vermont | |
| Centralia Oncology Clinic Centralia, Illinois | Site Public Contact - (morganthaler.jodi@mhsil.com) |
| Centre Hospitalier Universitaire de Sherbrooke-Fleurimont Sherbrooke, Quebec | Site Public Contact - (crcinformation.chus@ssss.gouv.qc.ca) |
| Centro Comprensivo de Cancer de UPR San Juan, | Site Public Contact - (Roster@nrgoncology.org) |
| Charleston Oncology - Roper Charleston, South Carolina | |
| Charleston Oncology - Saint Francis Charleston, South Carolina | |
| Chelsea Hospital Chelsea, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Chester County Hospital West Chester, Pennsylvania | Site Public Contact - (PMCancerResearch@pennmedicine.upenn.edu) |
| City of Hope Antelope Valley Lancaster, California | |
| City of Hope Comprehensive Cancer Center Duarte, California | Site Public Contact - (becomingapatient@coh.org) |
| City of Hope South Bay Torrance, California | |
| City of Hope South Pasadena South Pasadena, California | Site Public Contact - (becomingapatient@coh.org) |
| City of Hope Upland Upland, California | Site Public Contact - (becomingapatient@coh.org) |
| City of Hope at Irvine Lennar Irvine, California | |
| Clackamas Radiation Oncology Center Clackamas, Oregon | Site Public Contact - (CanRsrchStudies@providence.org) |
| Cleveland Clinic Akron General Akron, Ohio | Site Public Contact - (CancerAnswer@ccf.org) |
| Cleveland Clinic Cancer Center Independence Independence, Ohio | Site Public Contact - (TaussigResearch@ccf.org) |
| Cleveland Clinic Cancer Center Mansfield Mansfield, Ohio | Site Public Contact - (TaussigResearch@ccf.org) |
| Cleveland Clinic Cancer Center Strongsville Strongsville, Ohio | Site Public Contact - (TaussigResearch@ccf.org) |
| Cleveland Clinic Cancer Center/Fairview Hospital Cleveland, Ohio | Site Public Contact - (TaussigResearch@ccf.org) |
| Cleveland Clinic Foundation Cleveland, Ohio | Site Public Contact - (TaussigResearch@ccf.org) |
| Cleveland Clinic Mercy Hospital Canton, Ohio | |
| Cleveland Clinic Wooster Family Health and Surgery Center Wooster, Ohio | Site Public Contact - (TaussigResearch@ccf.org) |
| Cleveland Clinic-Weston Weston, Florida | |
| Coborn Cancer Center at Saint Cloud Hospital Saint Cloud, Minnesota | Site Public Contact - (coborncancercenter@centracare.com) |
| Columbus Oncology and Hematology Associates Dublin, Ohio | |
| Columbus Oncology and Hematology Associates Inc Columbus, Ohio | |
| CommonSpirit Cancer Center Mercy Durango, Colorado | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| CommonSpirit Saint Anthony Hospital Cancer Center Lakewood, Colorado | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| CommonSpirit Saint Joseph Hospital - Bardstown Bardstown, Kentucky | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| CommonSpirit Saint Joseph Hospital London London, Kentucky | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| CommonSpirit Saint Joseph Medical Center - East Lexington Lexington, Kentucky | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Commonwealth Cancer Center-Corbin Corbin, Kentucky | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Community Hospital of Anaconda Anaconda, Montana | Site Public Contact - (mccinfo@mtcancer.org) |
| Community Medical Center Toms River, New Jersey | Site Public Contact - (mccinfo@mtcancer.org) |
| Community Medical Center Toms River, New Jersey | Site Public Contact - (Lennette.Gonzales@rwjbh.org) |
| Community Medical Center Toms River, New Jersey | Site Public Contact - (cancerresearch@geisinger.edu) |
| Comprehensive Cancer Centers of Nevada Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Comprehensive Cancer Centers of Nevada - Central Valley Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Comprehensive Cancer Centers of Nevada - Henderson Henderson, Nevada | Site Public Contact - (research@sncrf.org) |
| Condell Memorial Hospital Libertyville, Illinois | Site Public Contact - (advocateresearch@advocatehealth.com) |
| Cone Health Cancer Center Greensboro, North Carolina | Site Public Contact - (stacey.phelps@conehealth.com) |
| Contra Costa Regional Medical Center Martinez, California | |
| Cooperman Barnabas Medical Center Livingston, New Jersey | |
| Corewell Health Beaumont Troy Hospital Troy, Michigan | |
| Corewell Health Dearborn Hospital Dearborn, Michigan | |
| Corewell Health Grand Rapids Hospitals - Butterworth Hospital Grand Rapids, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
| Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center Saint Joseph, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
| Corewell Health Reed City Hospital Reed City, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
| Corewell Health William Beaumont University Hospital Royal Oak, Michigan | |
| Covenant Health Cancer Centers Knoxville, Tennessee | |
| Covenant Health Cancer Centers - West Knoxville, Tennessee | |
| Covenant Health Oncology Group - Oak Ridge Oak Ridge, Tennessee | |
| Cox Cancer Center Branson Branson, Missouri | |
| CoxHealth South Hospital Springfield, Missouri | |
| Crossroads Cancer Center Effingham, Illinois | Site Public Contact - (morganthaler.jodi@mhsil.com) |
| Dana Farber-Merrimack Valley Methuen, Massachusetts | |
| Dana-Farber Cancer Institute at Boston Medical Center - Brighton Brighton, Massachusetts | |
| Dana-Farber Cancer Institute at Foxborough Foxborough, Massachusetts | |
| Dana-Farber/Brigham and Women's Cancer Center at Milford Regional Milford, Massachusetts | |
| Dana-Farber/Brigham and Women's Cancer Center at South Shore South Weymouth, Massachusetts | |
| Danbury Hospital Danbury, Connecticut | |
| Dartmouth Cancer Center - North Saint Johnsbury, Vermont | Site Public Contact - (cancer.research.nurse@hitchcock.org) |
| Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center Lebanon, New Hampshire | Site Public Contact - (cancer.research.nurse@dartmouth.edu) |
| Dayton Physician LLC - Englewood Dayton, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Dayton Physicians LLC - Troy Troy, Ohio | |
| Dayton Physicians LLC-Atrium Franklin, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Dayton Physicians LLC-Miami Valley South Centerville, Ohio | |
| Dayton Physicians LLC-Wayne Greenville, Ohio | |
| Decatur Memorial Hospital Decatur, Illinois | Site Public Contact - (morganthaler.jodi@mhsil.com) |
| Delaware Health Center-Grady Cancer Center Delaware, Ohio | |
| Dell Seton Medical Center at The University of Texas Austin, Texas | |
| Denver Health Medical Center Denver, Colorado | Site Public Contact - (ccrp@co-cancerresearch.org) |
| Dickinson County Healthcare System Iron Mountain, Michigan | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Dillon Health Center/Shaw Cancer Center Dillon, Colorado | |
| Divine Providence Hospital Williamsport, Pennsylvania | Site Public Contact - (Roster@nrgoncology.org) |
| Doctor H. Bliss Murphy Cancer Centre St. John's, Newfoundland and Labrador | |
| Doctors Cancer Center Manati, | |
| Doctors Hospital Columbus, Ohio | |
| Drexel Town Square Health Center Oak Creek, Wisconsin | |
| Dublin Methodist Hospital Dublin, Ohio | |
| Duke Cancer Center Cary Cary, North Carolina | Site Public Contact - (NCTNStudyTeam@dm.duke.edu) |
| Duke Cancer Center Raleigh Raleigh, North Carolina | Site Public Contact - (NCTNStudyTeam@dm.duke.edu) |
| Duke University Medical Center Durham, North Carolina | |
| Duluth Clinic Ashland Ashland, Wisconsin | Site Public Contact - (CancerTrials@EssentiaHealth.org) |
| East Carolina University Greenville, North Carolina | Site Public Contact - (eubankss@ecu.edu) |
| Eden Hospital Medical Center Castro Valley, California | Site Public Contact - (clinicalresearch@sutterhealth.org) |
| Edward Hines Jr VA Hospital Hines, Illinois | |
| Edward Hospital/Cancer Center Naperville, Illinois | |
| Edward Hospital/Cancer Center?Plainfield Plainfield, Illinois | Site Public Contact - (Cancerresearch@edward.org) |
| Eisenhower Army Medical Center Fort Eisenhower, Georgia | |
| Eisenhower Medical Center Rancho Mirage, California | |
| Elmhurst Memorial Hospital Elmhurst, Illinois | Site Public Contact - (Jrohde@emhc.org) |
| Enloe Medical Center Chico, California | |
| Ephrata Cancer Center Ephrata, Pennsylvania | |
| Epic Care Cyberknife Center Walnut Creek, California | |
| Epic Care Partners in Cancer Care Emeryville, California | |
| Epic Care-Dublin Dublin, California | |
| Essentia Health - Deer River Clinic Deer River, Minnesota | Site Public Contact - (CancerTrials@EssentiaHealth.org) |
| Essentia Health - Moose Lake Clinic Moose Lake, Minnesota | |
| Essentia Health Cancer Center Duluth, Minnesota | Site Public Contact - (CancerTrials@EssentiaHealth.org) |
| Essentia Health Cancer Center-South University Clinic Fargo, North Dakota | Site Public Contact - (CancerTrials@EssentiaHealth.org) |
| Essentia Health Hibbing Clinic Hibbing, Minnesota | |
| Essentia Health Saint Joseph's Medical Center Brainerd, Minnesota | Site Public Contact - (CancerTrials@EssentiaHealth.org) |
| Essentia Health Saint Mary's - Detroit Lakes Clinic Detroit Lakes, Minnesota | Site Public Contact - (CancerTrials@EssentiaHealth.org) |
| Essentia Health Saint Mary's Hospital - Superior Superior, Wisconsin | |
| Essentia Health Sandstone Sandstone, Minnesota | Site Public Contact - (CancerTrials@EssentiaHealth.org) |
| Essentia Health Virginia Clinic Virginia, Minnesota | Site Public Contact - (CancerTrials@EssentiaHealth.org) |
| Exeter Hospital Exeter, New Hampshire | |
| FHCC Overlake Bellevue, Washington | |
| FHCC at EvergreenHealth Kirkland, Washington | |
| FHCC at Northwest Hospital Seattle, Washington | |
| FMH James M Stockman Cancer Institute Frederick, Maryland | |
| Fairfield Medical Center Lancaster, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Fairview Clinics and Surgery Center Maple Grove Maple Grove, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Fairview Lakes Medical Center Wyoming, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Fairview Northland Medical Center Princeton, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Fairview Ridges Hospital Burnsville, Minnesota | |
| Fairview Southdale Hospital Edina, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Farmington Health Center Farmington, Utah | Site Public Contact - (cancerinfo@hci.utah.edu) |
| FirstHealth of the Carolinas-Moore Regional Hospital Pinehurst, North Carolina | Site Public Contact - (jcwilliams@firsthealth.org) |
| Forbes Hospital Monroeville, Pennsylvania | |
| Fox Chase Cancer Center Philadelphia, Pennsylvania | |
| Franciscan Research Center-Northwest Medical Plaza Tacoma, Washington | |
| Fred Hutchinson Cancer Center Seattle, Washington | |
| Frederick Memorial Hospital Frederick, Maryland | |
| Freeman Health System Joplin, Missouri | Site Public Contact - (LJCrockett@freemanhealth.com) |
| Fremont - Rideout Cancer Center Marysville, California | |
| Froedtert Menomonee Falls Hospital Menomonee Falls, Wisconsin | |
| Froedtert West Bend Hospital/Kraemer Cancer Center West Bend, Wisconsin | |
| Garnet Health Medical Center Middletown, New York | Site Public Contact - (jgerlach@garnethealth.org) |
| Geauga Hospital Chardon, Ohio | |
| Geisinger Medical Center Danville, Pennsylvania | Site Public Contact - (cancerresearch@geisinger.edu) |
| Geisinger Medical Center-Cancer Center Hazleton Hazleton, Pennsylvania | Site Public Contact - (cancerresearch@geisinger.edu) |
| Geisinger Medical Oncology-Lewisburg Lewisburg, Pennsylvania | Site Public Contact - (cancerresearch@geisinger.edu) |
| Geisinger Wyoming Valley/Henry Cancer Center Wilkes-Barre, Pennsylvania | Site Public Contact - (HemonCCTrials@geisinger.edu) |
| Gene Upshaw Memorial Tahoe Forest Cancer Center Truckee, California | |
| Genesee Hematology Oncology PC Flint, Michigan | Site Public Contact - (wstrong@ghci.org) |
| Genesis Healthcare System Cancer Care Center Zanesville, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Genesys Hurley Cancer Institute Flint, Michigan | Site Public Contact - (wstrong@ghci.org) |
| George Washington University Medical Center Washington D.C., District of Columbia | |
| Gibbs Cancer Center-Gaffney Gaffney, South Carolina | Site Public Contact - (kmertz-rivera@gibbscc.org) |
| Gibbs Cancer Center-Pelham Greer, South Carolina | Site Public Contact - (kmertz-rivera@gibbscc.org) |
| Glens Falls Hospital Glens Falls, New York | |
| Good Samaritan Hospital - Cincinnati Cincinnati, Ohio | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Grady Memorial Hospital Delaware, Ohio | |
| Grand Valley Oncology Grand Junction, Colorado | Site Public Contact - (gvoclinicaltrials@gjhosp.org) |
| Grand View Hospital Sellersville, Pennsylvania | |
| Grant Medical Center Columbus, Ohio | |
| Great Falls Clinic Great Falls, Montana | Site Public Contact - (mccinfo@mtcancer.org) |
| Greater Baltimore Medical Center Baltimore, Maryland | |
| Greater Dayton Cancer Center Kettering, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Greater Regional Medical Center Creston, Iowa | |
| Gundersen Lutheran Medical Center La Crosse, Wisconsin | Site Public Contact - (cancerctr@gundersenhealth.org) |
| HSHS Sacred Heart Hospital Eau Claire, Wisconsin | |
| Harold Alfond Center for Cancer Care Augusta, Maine | |
| Hawaii Cancer Care - Westridge ‘Aiea, Hawaii | Site Public Contact - (info@hawaiicancercare.com) |
| Hawaii Cancer Care Inc - Waterfront Plaza Honolulu, Hawaii | Site Public Contact - (i.webster@hawaiicancercare.com) |
| Health Partners Inc Minneapolis, Minnesota | |
| Heartland Regional Medical Center Saint Joseph, Missouri | Site Public Contact - (Trisha.England2@mymlc.com) |
| Helen F Graham Cancer Center Newark, Delaware | Site Public Contact - (lbarone@christianacare.org) |
| Hematology Oncology Consultants-Clarkston Clarkston, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Hennepin County Medical Center Minneapolis, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Henry Ford Health Providence Novi Hospital Novi, Michigan | Site Public Contact - (kfife3@hfhs.org) |
| Henry Ford Health Providence Southfield Hospital Southfield, Michigan | Site Public Contact - (kfife3@hfhs.org) |
| Henry Ford Health Saint John Hospital Detroit, Michigan | Site Public Contact - (Kkeenan1@hfhs.org) |
| Henry Ford Health Warren Hospital Warren, Michigan | Site Public Contact - (kforman1@hfhs.org) |
| Henry Ford Madison Heights Hospital - Breast Warren, Michigan | Site Public Contact - (kforman1@hfhs.org) |
| Henry Ford River District Hospital East China Township, Michigan | Site Public Contact - (kforman1@hfhs.org) |
| Henry Ford Saint John Hospital - Academic Grosse Pointe Woods, Michigan | Site Public Contact - (kforman1@hfhs.org) |
| Henry Ford Saint John Hospital - Breast Grosse Pointe Woods, Michigan | Site Public Contact - (karen.forman@ascension.org) |
| Henry Ford Saint John Hospital - Macomb Medical Macomb, Michigan | Site Public Contact - (kforman1@hfhs.org) |
| Henry Ford Saint John Hospital - Van Elslander Grosse Pointe Woods, Michigan | Site Public Contact - (kforman1@hfhs.org) |
| Henry Ford Warren Hospital - Breast Macomb Macomb, Michigan | Site Public Contact - (kforman1@hfhs.org) |
| Henry Ford Warren Hospital - GLCMS Warren, Michigan | Site Public Contact - (kforman1@hfhs.org) |
| Highline Medical Center-Main Campus Burien, Washington | |
| Hillcrest Hospital Cancer Center Mayfield Heights, Ohio | Site Public Contact - (TaussigResearch@ccf.org) |
| Holy Cross Hospital Fort Lauderdale, Florida | Site Public Contact - (eileen.georgi@holy-cross.com) |
| Hope Cancer Center Pontiac, Michigan | |
| Hopital du Sacre-Coeur de Montreal Montreal, Quebec | |
| Hotel-Dieu de Levis Lévis, Quebec | Site Public Contact - (ctsucontact@westat.com) |
| Humber River Hospital Toronto, Ontario | Site Public Contact - (research@hrh.ca) |
| Huntsman Cancer Institute/University of Utah Salt Lake City, Utah | Site Public Contact - (cancerinfo@hci.utah.edu) |
| Hurley Medical Center Flint, Michigan | Site Public Contact - (wstrong@ghci.org) |
| Huron Gastroenterology PC Ypsilanti, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| IRMC Cancer Center Indiana, Pennsylvania | Site Public Contact - (haneydl@upmc.edu) |
| Illinois CancerCare - Washington Washington, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Bloomington Bloomington, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Canton Canton, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Carthage Carthage, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Dixon Dixon, Illinois | |
| Illinois CancerCare-Eureka Eureka, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Galesburg Galesburg, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Kewanee Clinic Kewanee, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Macomb Macomb, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Ottawa Clinic Ottawa, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Pekin Pekin, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Peoria Peoria, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Peru Peru, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Princeton Princeton, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Indu and Raj Soin Medical Center Beavercreek, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Ingalls Memorial Hospital Harvey, Illinois | Site Public Contact - (clinicaltrials@ingalls.org) |
| Integris Cancer Institute of Oklahoma Oklahoma City, Oklahoma | |
| Integris Southwest Medical Center Oklahoma City, Oklahoma | Site Public Contact - (Roster@nrgoncology.org) |
| Intermountain Health Platte Valley Hospital Brighton, Colorado | Site Public Contact - (peaksresearch@imail.org) |
| Intermountain Medical Center Murray, Utah | Site Public Contact - (officeofresearch@imail.org) |
| Iowa Methodist Medical Center Des Moines, Iowa | |
| Jefferson Cherry Hill Hospital Cherry Hill, New Jersey | Site Public Contact - (ONCTrialNow@jefferson.edu) |
| Jefferson Hospital Jefferson Hills, Pennsylvania | Site Public Contact - (ddefazio@wpahs.org) |
| Jefferson Methodist Hospital Philadelphia, Pennsylvania | |
| Jefferson Torresdale Hospital Philadelphia, Pennsylvania | Site Public Contact - (ONCTrialNow@jefferson.edu) |
| Jersey City Medical Center Jersey City, New Jersey | Site Public Contact - (Roster@nrgoncology.org) |
| Jewish General Hospital Montreal, Quebec | |
| Jewish Hospital Louisville, Kentucky | |
| Jewish Hospital Medical Center South Shepherdsville, Kentucky | |
| John H Stroger Jr Hospital of Cook County Chicago, Illinois | |
| John Muir Medical Center-Walnut Creek Walnut Creek, California | Site Public Contact - (clinicalresearch@johnmuirhealth.com) |
| Jupiter Medical Center Jupiter, Florida | |
| Juravinski Cancer Centre at Hamilton Health Sciences Hamilton, Ontario | |
| Kadlec Clinic Hematology and Oncology Kennewick, Washington | Site Public Contact - (research@kadlecmed.org) |
| Kaiser Permanente - Largo Medical Center Largo, Maryland | Site Public Contact - (Charmaine.A.Mckie@kp.org) |
| Kaiser Permanente - Panorama City Panorama City, California | Site Public Contact - (clinical.trials@kp.org) |
| Kaiser Permanente Downtown Commons Sacramento, California | Site Public Contact - (kpoct@kp.org) |
| Kaiser Permanente Dublin Dublin, California | |
| Kaiser Permanente Fresno Orchard Plaza Fresno, California | |
| Kaiser Permanente Los Angeles Medical Center Los Angeles, California | Site Public Contact - (clinical.trials@kp.org) |
| Kaiser Permanente Lutherville - Timonium Medical Center Lutherville, Maryland | Site Public Contact - (Charmaine.A.Mckie@kp.org) |
| Kaiser Permanente Medical Center - Santa Clara Santa Clara, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente Medical Center-Vacaville Vacaville, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente Moanalua Medical Center Honolulu, Hawaii | Site Public Contact - (shelley.a.clark@kp.org) |
| Kaiser Permanente Northwest Portland, Oregon | Site Public Contact - (information@kpchr.org) |
| Kaiser Permanente San Leandro San Leandro, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente South Bay Harbor City, California | Site Public Contact - (clinical.trials@kp.org) |
| Kaiser Permanente Tysons Corner Medical Center McLean, Virginia | Site Public Contact - (Charmaine.A.Mckie@kp.org) |
| Kaiser Permanente West Los Angeles Los Angeles, California | Site Public Contact - (clinical.trials@kp.org) |
| Kaiser Permanente- Marshall Medical Offices Redwood City, California | |
| Kaiser Permanente- Modesto MOB II Modesto, California | |
| Kaiser Permanente-Anaheim Anaheim, California | Site Public Contact - (clinical.trials@kp.org) |
| Kaiser Permanente-Baldwin Park Baldwin Park, California | Site Public Contact - (clinical.trials@kp.org) |
| Kaiser Permanente-Bellflower Bellflower, California | Site Public Contact - (clinical.trials@kp.org) |
| Kaiser Permanente-Burke Medical Center Burke, Virginia | Site Public Contact - (Charmaine.A.Mckie@kp.org) |
| Kaiser Permanente-Capitol Hill Medical Center Washington D.C., District of Columbia | Site Public Contact - (Charmaine.A.Mckie@kp.org) |
| Kaiser Permanente-Caton Hill Medical Center Woodbridge, Virginia | Site Public Contact - (Charmaine.A.Mckie@kp.org) |
| Kaiser Permanente-Deer Valley Medical Center Antioch, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-Fontana Fontana, California | Site Public Contact - (clinical.trials@kp.org) |
| Kaiser Permanente-Franklin Denver, Colorado | Site Public Contact - (KPCOIHRClinicalResearch@kp.org) |
| Kaiser Permanente-Fremont Fremont, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-Fresno Fresno, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-Gaithersburg Medical Center Gaithersburg, Maryland | Site Public Contact - (Charmaine.A.Mckie@kp.org) |
| Kaiser Permanente-Irvine Irvine, California | Site Public Contact - (clinical.trials@kp.org) |
| Kaiser Permanente-Lone Tree Lone Tree, Colorado | Site Public Contact - (KPCOIHRClinicalResearch@kp.org) |
| Kaiser Permanente-Modesto Modesto, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-Oakland Oakland, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-Ontario Ontario, California | Site Public Contact - (clinical.trials@kp.org) |
| Kaiser Permanente-Richmond Richmond, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-Riverside Riverside, California | Site Public Contact - (clinical.trials@kp.org) |
| Kaiser Permanente-Rock Creek Lafayette, Colorado | Site Public Contact - (KPCOIHRClinicalResearch@kp.org) |
| Kaiser Permanente-Roseville Roseville, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-San Diego Zion San Diego, California | Site Public Contact - (clinical.trials@kp.org) |
| Kaiser Permanente-San Francisco San Francisco, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-San Marcos San Marcos, California | Site Public Contact - (clinical.trials@kp.org) |
| Kaiser Permanente-Santa Rosa Santa Rosa, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-Santa Teresa-San Jose San Jose, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-South Sacramento Sacramento, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-South San Francisco South San Francisco, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-Stockton Stockton, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-Vallejo Vallejo, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-Walnut Creek Walnut Creek, California | Site Public Contact - (Kpoct@kp.org) |
| Kaiser Permanente-Woodland Hills Woodland Hills, California | Site Public Contact - (clinical.trials@kp.org) |
| Kaiser Permanente-Woodlawn Medical Center Baltimore, Maryland | Site Public Contact - (Charmaine.A.Mckie@kp.org) |
| Kaiser San Rafael-Gallinas San Rafael, California | Site Public Contact - (Kpoct@kp.org) |
| Keck Medicine of USC Koreatown Los Angeles, California | |
| Kettering Medical Center Kettering, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Kingman Regional Medical Center Kingman, Arizona | Site Public Contact - (research@sncrf.org) |
| Kingston Health Sciences Centre Kingston, Ontario | Site Public Contact - (cc-clinicaltrials@kgh.kari.net) |
| Knox Community Hospital Mount Vernon, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Kootenai Clinic Cancer Services - Post Falls Post Falls, Idaho | Site Public Contact - (mccinfo@mtcancer.org) |
| Kootenai Clinic Cancer Services - Sandpoint Sandpoint, Idaho | Site Public Contact - (mccinfo@mtcancer.org) |
| Kootenai Health - Coeur d'Alene Coeur d'Alene, Idaho | Site Public Contact - (mccinfo@mtcancer.org) |
| LDS Hospital Salt Lake City, Utah | Site Public Contact - (officeofresearch@imail.org) |
| LSU Health Baton Rouge-North Clinic Baton Rouge, Louisiana | Site Public Contact - (research@ololrmc.com) |
| Lahey Clinic Burlington, Massachusetts | Site Public Contact - (lhmc-cancer-clinical-trials@lahey.org) |
| Lahey Clinic Peabody Peabody, Massachusetts | Site Public Contact - (lhmc-cancer-clinical-trials@lahey.org) |
| Lakeridge Health Oshawa Oshawa, Ontario | |
| Lakeview Hospital Stillwater, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Lancaster General Ann B Barshinger Cancer Institute Lancaster, Pennsylvania | |
| Lancaster General Hospital Lancaster, Pennsylvania | |
| Laura and Isaac Perlmutter Cancer Center at NYU Langone New York, New York | |
| Legacy Cancer Institute Medical Oncology and Day Treatment Vancouver, Washington | Site Public Contact - (oncologyresearch@lhs.org) |
| Legacy Good Samaritan Hospital and Medical Center Portland, Oregon | Site Public Contact - (cancer@lhs.org) |
| Legacy Meridian Park Hospital Tualatin, Oregon | |
| Legacy Mount Hood Medical Center Gresham, Oregon | |
| Legacy Salmon Creek Hospital Vancouver, Washington | |
| Lehigh Valley Hospital - Muhlenberg Bethlehem, Pennsylvania | Site Public Contact - (Morgan_M.Horton@lvhn.org) |
| Lehigh Valley Hospital-Cedar Crest Allentown, Pennsylvania | Site Public Contact - (Morgan_M.Horton@lvhn.org) |
| Lehigh Valley Hospital-Hazleton Hazleton, Pennsylvania | Site Public Contact - (Morgan_M.Horton@lvhn.org) |
| Lenox Hill Hospital New York, New York | |
| Levine Cancer Institute-Ballantyne Charlotte, North Carolina | |
| Levine Cancer Institute-SouthPark Charlotte, North Carolina | |
| Licking Memorial Hospital Newark, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Logan Health Medical Center Kalispell, Montana | Site Public Contact - (mccinfo@mtcancer.org) |
| Logan Regional Hospital Logan, Utah | Site Public Contact - (officeofresearch@imail.org) |
| Loma Linda University Medical Center Loma Linda, California | |
| London Regional Cancer Program London, Ontario | |
| Long Beach Memorial Medical Center-Todd Cancer Institute Long Beach, California | |
| Longmont United Hospital Longmont, Colorado | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Los Angeles General Medical Center Los Angeles, California | Site Public Contact - (uscnorrisinfo@med.usc.edu) |
| Louisiana State University Health Science Center New Orleans, Louisiana | Site Public Contact - (emede1@lsuhsc.edu) |
| Loyola University Medical Center Maywood, Illinois | |
| Lutheran Hospital - Cancer Centers of Colorado Golden, Colorado | Site Public Contact - (peaksresearch@imail.org) |
| Lyndon Baines Johnson General Hospital Houston, Texas | |
| MU Health - University Hospital/Ellis Fischel Cancer Center Columbia, Missouri | |
| MU Health Care Goldschmidt Cancer Center Jefferson City, Missouri | |
| Macomb Hematology Oncology PC Warren, Michigan | |
| MaineHealth Cancer Care Center of York County Sanford, Maine | |
| MaineHealth Cancer Care and IV Therapy - Sanford Sanford, Maine | Site Public Contact - (clinicalresearch@mainehealth.org) |
| MaineHealth Cancer Care and IV Therapy - South Portland South Portland, Maine | Site Public Contact - (clinicalresearch@mainehealth.org) |
| MaineHealth Maine Medical Center - Biddeford Biddeford, Maine | |
| MaineHealth Maine Medical Center- Scarborough Scarborough, Maine | Site Public Contact - (clinicalresearch@mainehealth.org) |
| Manhattan Eye Ear and Throat Hospital New York, New York | |
| Margaret R Pardee Memorial Hospital Hendersonville, North Carolina | Site Public Contact - (pardeecancerresearch@unchealth.unc.edu) |
| Marietta Memorial Hospital Marietta, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Markham Stouffville Hospital Markham, Ontario | Site Public Contact - (ctsucontact@westat.com) |
| Marshall Cancer Center Cameron Park, California | Site Public Contact - (cancerservices@marshallmedical.org) |
| Marshfield Clinic - Wisconsin Rapids Center Wisconsin Rapids, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Clinic-Chippewa Center Chippewa Falls, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Clinic-Wausau Center Wausau, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center - Ladysmith Ladysmith, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center - Minocqua Minocqua, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center - Neillsville Neillsville, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center - Weston Weston, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center-EC Cancer Center Eau Claire, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center-Marshfield Marshfield, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center-Rice Lake Rice Lake, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center-River Region at Stevens Point Stevens Point, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Mary Greeley Medical Center Ames, Iowa | |
| Mayo Clinic Health System-Eau Claire Clinic Eau Claire, Wisconsin | |
| Mayo Clinic Health System-Franciscan Healthcare La Crosse, Wisconsin | |
| Mayo Clinic Hospital in Arizona Phoenix, Arizona | |
| Mayo Clinic in Rochester Rochester, Minnesota | |
| McFarland Clinic - Ames Ames, Iowa | Site Public Contact - (ksoder@mcfarlandclinic.com) |
| McFarland Clinic - Boone Boone, Iowa | |
| McFarland Clinic - Jefferson Jefferson, Iowa | |
| McFarland Clinic - Marshalltown Marshalltown, Iowa | |
| McFarland Clinic - Trinity Cancer Center Fort Dodge, Iowa | |
| McKay-Dee Hospital Center Ogden, Utah | Site Public Contact - (officeofresearch@imail.org) |
| MedStar Franklin Square Medical Center/Weinberg Cancer Institute Baltimore, Maryland | |
| MedStar Georgetown University Hospital Washington D.C., District of Columbia | |
| MedStar Good Samaritan Hospital Baltimore, Maryland | Site Public Contact - (Barbara.rector@medstar.net) |
| MedStar Montgomery Medical Center Olney, Maryland | |
| MedStar Southern Maryland Hospital Center Clinton, Maryland | |
| Medical Center of Baton Rouge Baton Rouge, Louisiana | Site Public Contact - (Camille.Beck@Ochsner.org) |
| Medical Center of the Rockies Loveland, Colorado | |
| Medical College of Wisconsin Milwaukee, Wisconsin | |
| Medical Oncology Hematology Consultants PA Newark, Delaware | Site Public Contact - (lbarone@christianacare.org) |
| Medical University of South Carolina Charleston, South Carolina | Site Public Contact - (hcc-clinical-trials@musc.edu) |
| Medstar Washington Hospital Center Washington D.C., District of Columbia | |
| Memorial Health University Medical Center Savannah, Georgia | Site Public Contact - (Lorraine.OHara@hcahealthcare.com) |
| Memorial Hospital East Shiloh, Illinois | Site Public Contact - (dschwab@wustl.edu) |
| Memorial Hospital North Colorado Springs, Colorado | |
| Memorial Hospital West Pembroke Pines, Florida | |
| Memorial Hospital of Carbondale Carbondale, Illinois | Site Public Contact - (clinical.research@sih.net) |
| Memorial Medical Center Modesto, California | Site Public Contact - (clinicalresearch@sutterhealth.org) |
| Memorial Medical Center-Las Cruces Las Cruces, New Mexico | Site Public Contact - (Deborah.Brown@LPNT.net) |
| Memorial Regional Hospital/Joe DiMaggio Children's Hospital Hollywood, Florida | Site Public Contact - (OHR@mhs.net) |
| Mercy Cancer Center - Cape Girardeau Cape Girardeau, Missouri | |
| Mercy Cancer Center - Carmichael Carmichael, California | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Mercy Cancer Center - Elk Grove Elk Grove, California | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Mercy Cancer Center - Rocklin Rocklin, California | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Mercy Cancer Center - Sacramento Sacramento, California | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Mercy Cancer Center-West Lakes Clive, Iowa | |
| Mercy Clinic-Rolla-Cancer and Hematology Rolla, Missouri | |
| Mercy Health - Perrysburg Hospital Perrysburg, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Mercy Health - Saint Anne Hospital Toledo, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Mercy Health - Saint Vincent Hospital Toledo, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Mercy Health Sylvania Radiation Oncology Center Toledo, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Mercy Hospital Coon Rapids, Minnesota | |
| Mercy Hospital Coon Rapids, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Mercy Hospital Fort Smith Fort Smith, Arkansas | |
| Mercy Hospital Joplin Joplin, Missouri | Site Public Contact - (esmeralda.carrillo@mercy.net) |
| Mercy Hospital Oklahoma City Oklahoma City, Oklahoma | |
| Mercy Hospital Saint Louis St Louis, Missouri | |
| Mercy Hospital South St Louis, Missouri | Site Public Contact - (Danielle.Werle@mercy.net) |
| Mercy Hospital Springfield Springfield, Missouri | |
| Mercy Hospital Washington Washington, Missouri | |
| Mercy Infusion Center - Chippewa St Louis, Missouri | |
| Mercy Medical Center Springfield, Massachusetts | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Mercy Medical Center - Des Moines Des Moines, Iowa | |
| Mercy Medical Center-West Lakes West Des Moines, Iowa | |
| Mercy Oncology and Hematology - Clayton-Clarkson Ballwin, Missouri | |
| Mercy San Juan Medical Center Carmichael, California | Site Public Contact - (ResearchInstituteInquiries@commonspirit.org) |
| Mercyhealth Hospital and Cancer Center - Janesville Janesville, Wisconsin | Site Public Contact - (oncologyclinicaltrials@mhemail.org) |
| Methodist Medical Center of Illinois Peoria, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| MetroHealth Medical Center Cleveland, Ohio | |
| Miami Valley Cancer Care and Infusion Greenville, Ohio | |
| Miami Valley Hospital Dayton, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Miami Valley Hospital North Dayton, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Miami Valley Hospital South Centerville, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Michigan Healthcare Professionals Pontiac Pontiac, Michigan | Site Public Contact - (Emily.Crofts@trinity-health.org) |
| Midlands Community Hospital Papillion, Nebraska | |
| Mills Health Center San Mateo, California | Site Public Contact - (clinicalresearch@sutterhealth.org) |
| Mills-Peninsula Medical Center Burlingame, California | Site Public Contact - (clinicalresearch@sutterhealth.org) |
| Minnesota Oncology - Burnsville Burnsville, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Minnesota Oncology - Coon Rapids Coon Rapids, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Minnesota Oncology - Edina Edina, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Minnesota Oncology - Maple Grove Maple Grove, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Minnesota Oncology Hematology PA-Chaska Chaska, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Minnesota Oncology Hematology PA-Maplewood Maplewood, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Minnesota Oncology Hematology PA-Woodbury Woodbury, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Mission Hope Medical Oncology - Arroyo Grande Arroyo Grande, California | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Mission Hope Medical Oncology - Santa Maria Santa Maria, California | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Missouri Baptist Medical Center St Louis, Missouri | |
| Missouri Baptist Sullivan Hospital Sullivan, Missouri | |
| Mobile Infirmary Medical Center Mobile, Alabama | |
| Moffitt Cancer Center Tampa, Florida | Site Public Contact - (ClinicalTrials@moffitt.org) |
| Moffitt Cancer Center - McKinley Campus Tampa, Florida | Site Public Contact - (ClinicalTrials@moffitt.org) |
| Moffitt Cancer Center at Wesley Chapel Wesley Chapel, Florida | Site Public Contact - (ClinicalTrials@moffitt.org) |
| Moffitt Cancer Center-International Plaza Tampa, Florida | Site Public Contact - (ClinicalTrials@moffitt.org) |
| Monmouth Medical Center Long Branch, New Jersey | Site Public Contact - (mary.danish@rwjbh.org) |
| Monmouth Medical Center Southern Campus Lakewood, New Jersey | Site Public Contact - (mary.danish@rwjbh.org) |
| Montefiore Medical Center-Einstein Campus The Bronx, New York | Site Public Contact - (eskwak@montefiore.org) |
| Monticello Cancer Center Monticello, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Morristown Medical Center Morristown, New Jersey | |
| Morton Plant Hospital Clearwater, Florida | |
| Mount Carmel East Hospital Columbus, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Mount Carmel Grove City Hospital Grove City, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Mount Carmel Health Center West Columbus, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Mount Carmel New Albany Surgical Hospital New Albany, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Mount Sinai - Rockville Center Rockville Centre, New York | Site Public Contact - (crsu@mssm.edu) |
| Mount Sinai - Wantagh Wantagh, New York | Site Public Contact - (crsu@mssm.edu) |
| Mount Sinai Doctors - Valley Stream Valley Stream, New York | Site Public Contact - (crsu@mssm.edu) |
| Mount Sinai Hospital New York, New York | Site Public Contact - (CCTO@mssm.edu) |
| Mount Sinai Hospital Medical Center Chicago, Illinois | Site Public Contact - (suhi@sinai.org) |
| Mount Sinai South Nassau Oceanside, New York | Site Public Contact - (crsu@mssm.edu) |
| Mount Sinai West New York, New York | Site Public Contact - (CCTO@mssm.edu) |
| Munson Medical Center Traverse City, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
| MyMichigan Medical Center Saginaw Saginaw, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| MyMichigan Medical Center Tawas Tawas City, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro Jonesboro, Arkansas | Site Public Contact - (Emily.Carvell@bmhcc.org) |
| NYP/Weill Cornell Medical Center New York, New York | |
| NYU Langone Hospital - Long Island Mineola, New York | |
| National Jewish Health-Western Hematology Oncology Golden, Colorado | |
| Nebraska Cancer Specialists/Oncology Hematology West PC Grand Island, Nebraska | |
| New Hampshire Oncology Hematology PA-Concord Concord, New Hampshire | |
| New Ulm Medical Center New Ulm, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| New York-Presbyterian/Brooklyn Methodist Hospital Brooklyn, New York | Site Public Contact - (Adg9003@nyp.org) |
| Newark Beth Israel Medical Center Newark, New Jersey | Site Public Contact - (Christine.Kosmides@rwjbh.org) |
| Newark Radiation Oncology Newark, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Newland Medical Associates-Clarkston Clarkston, Michigan | |
| Newland Medical Associates-Pontiac Pontiac, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Niagara Health System-Saint Catharines General Saint Catharines, Ontario | |
| North Coast Cancer Care Sandusky, Ohio | Site Public Contact - (TaussigResearch@ccf.org) |
| North Memorial Medical Health Center Robbinsdale, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| North Star Lodge Cancer Center at Yakima Valley Memorial Hospital Yakima, Washington | Site Public Contact - (Memorial-ClinicalTrials@yvmh.org) |
| North York General Hospital North York, Ontario | |
| NorthShore University HealthSystem-Evanston Hospital Evanston, Illinois | |
| NorthShore University HealthSystem-Glenbrook Hospital Glenview, Illinois | |
| NorthShore University HealthSystem-Highland Park Hospital Highland Park, Illinois | |
| Northern Westchester Hospital Mount Kisco, New York | Site Public Contact - (AMellor@northwell.edu) |
| Northside Hospital Atlanta, Georgia | Site Public Contact - (ClinicalTrials@northside.com) |
| Northside Hospital - Duluth Duluth, Georgia | Site Public Contact - (Clinical.trials@northside.com) |
| Northside Hospital - Gwinnett Lawrenceville, Georgia | Site Public Contact - (Clinical.trials@northside.com) |
| Northwell Health Cancer Institute at Huntington Greenlawn, New York | |
| Northwell Health/Center for Advanced Medicine Lake Success, New York | |
| Northwest Cancer Center - Crown Point Crown Point, Indiana | Site Public Contact - (CancerResearch@powershealth.org) |
| Northwest Cancer Center - Hobart Hobart, Indiana | |
| Northwest Cancer Center - Valparaiso Valparaiso, Indiana | Site Public Contact - (CancerResearch@COMHS.org) |
| Northwest Oncology LLC Dyer, Indiana | |
| Northwestern Medicine Cancer Center Delnor Geneva, Illinois | Site Public Contact - (Donald.Smith3@nm.org) |
| Northwestern Medicine Cancer Center Kishwaukee DeKalb, Illinois | Site Public Contact - (Donald.Smith3@nm.org) |
| Northwestern Medicine Cancer Center Warrenville Warrenville, Illinois | Site Public Contact - (Donald.Smith3@nm.org) |
| Northwestern Medicine Glenview Outpatient Center Glenview, Illinois | |
| Northwestern Medicine Grayslake Outpatient Center Grayslake, Illinois | |
| Northwestern Medicine Lake Forest Hospital Lake Forest, Illinois | Site Public Contact - (cancertrials@northwestern.edu) |
| Northwestern Medicine Orland Park Orland Park, Illinois | Site Public Contact - (nctnprogram_rhlccc@northwestern.edu) |
| Northwestern University Chicago, Illinois | Site Public Contact - (cancer@northwestern.edu) |
| Norton Audubon Hospital and Medical Campus Louisville, Kentucky | |
| Norton Brownsboro Hospital and Medical Campus Louisville, Kentucky | Site Public Contact - (Roster@nrgoncology.org) |
| Norton Hospital Pavilion and Medical Campus Louisville, Kentucky | Site Public Contact - (cancerresearch@nortonhealthcare.org) |
| Norwalk Hospital Norwalk, Connecticut | Site Public Contact - (jennifer.long@norwalkhealth.org) |
| OSF Saint Anthony's Health Center Alton, Illinois | |
| OSF Saint Francis Hospital and Medical Group Escanaba, Michigan | Site Public Contact - (WI_research_admin@hshs.org) |
| Ochsner Hematology Oncology North Shore - Covington (West Region) Covington, Louisiana | Site Public Contact - (Cheryl.kesler@ochsner.org) |
| Ochsner High Grove Baton Rouge, Louisiana | Site Public Contact - (Camielle.beck@ochsner.org) |
| Ochsner Medical Center Jefferson New Orleans, Louisiana | Site Public Contact - (Elisemarie.curry@ochsner.org) |
| Odette Cancer Centre- Sunnybrook Health Sciences Centre Toronto, Ontario | |
| Ohio State University Comprehensive Cancer Center Columbus, Ohio | Site Public Contact - (Jamesline@osumc.edu) |
| OhioHealth Mansfield Hospital Mansfield, Ohio | |
| OhioHealth Marion General Hospital Marion, Ohio | |
| Oklahoma Cancer Specialists and Research Institute-Tulsa Tulsa, Oklahoma | |
| Oncology Associates at Mercy Medical Center Cedar Rapids, Iowa | |
| Oncology Hematology Associates of Saginaw Valley PC Saginaw, Michigan | |
| Oncology Hematology Care Inc-Kenwood Cincinnati, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| OptumCare Cancer Care at Charleston Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| OptumCare Cancer Care at Fort Apache Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Orange Coast Memorial Medical Center Fountain Valley, California | |
| Orion Cancer Care Findlay, Ohio | |
| Orlando Health Cancer Institute Orlando, Florida | Site Public Contact - (CancerClinicalTrials@orlandohealth.com) |
| Orlando Health Cancer Institute - Lake Mary Lake Mary, Florida | Site Public Contact - (r-adultoncnewops@orlandohealth.com) |
| Ottawa Hospital and Cancer Center-General Campus Ottawa, Ontario | |
| Our Lady of the Lake Physician Group Baton Rouge, Louisiana | Site Public Contact - (research@ololrmc.com) |
| Overlook Hospital Summit, New Jersey | |
| PCR Oncology Arroyo Grande, California | Site Public Contact - (research@sncrf.org) |
| PROncology San Juan, | Site Public Contact - (info@PRoncology.com) |
| Pacific Central Coast Health Center-San Luis Obispo San Luis Obispo, California | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Pali Momi Medical Center ‘Aiea, Hawaii | |
| Palo Alto Medical Foundation Health Care Palo Alto, California | Site Public Contact - (clinicalresearch@sutterhealth.org) |
| Palo Alto Medical Foundation-Camino Division Mountain View, California | Site Public Contact - (clinicalresearch@sutterhealth.org) |
| Palo Alto Medical Foundation-Fremont Fremont, California | Site Public Contact - (clinicalresearch@sutterhealth.org) |
| Palo Alto Medical Foundation-Gynecologic Oncology Mountain View, California | Site Public Contact - (clinicalresearch@sutterhealth.org) |
| Palo Alto Medical Foundation-Santa Cruz Santa Cruz, California | Site Public Contact - (clinicalresearch@sutterhealth.org) |
| Palo Alto Medical Foundation-Sunnyvale Sunnyvale, California | Site Public Contact - (clinicalresearch@sutterhealth.org) |
| Pan American Center for Oncology Trials LLC San Juan, | Site Public Contact - (marcia.cruzcorrea@panoncologytrials.com) |
| Pan American Center for Oncology Trials LLC - Cayey Cayey, | Site Public Contact - (info@panoncologytrials.com) |
| Pan American Center for Oncology Trials LLC - Ciudadela San Juan, | Site Public Contact - (info@panoncologytrials.com) |
| Pan American Center for Oncology Trials LLC - Dorado Dorado, | Site Public Contact - (info@panoncologytrials.com) |
| Pan American Center for Oncology Trials LLC - Mayaguez San Juan, PR | Site Public Contact - (ctsucontact@westat.com) |
| Park Nicollet Clinic - Saint Louis Park Saint Louis Park, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Parkland Health Center - Farmington Farmington, Missouri | |
| Parkland Memorial Hospital Dallas, Texas | Site Public Contact - (canceranswerline@UTSouthwestern.edu) |
| Parkview Regional Medical Center Fort Wayne, Indiana | |
| Peninsula Cancer Institute-Cancer Specialists of Tidewater Virginia Beach, Virginia | Site Public Contact - (casey.morris@rivhs.com) |
| Peninsula Cancer Institute-Gloucester Gloucester, Virginia | Site Public Contact - (casey.morris@rivhs.com) |
| Peninsula Cancer Institute-Newport News Newport News, Virginia | Site Public Contact - (casey.morris@rivhs.com) |
| Peninsula Cancer Institute-Williamsburg Williamsburg, Virginia | Site Public Contact - (casey.morris@rivhs.com) |
| Penn State Milton S Hershey Medical Center Hershey, Pennsylvania | Site Public Contact - (CTO@hmc.psu.edu) |
| Pennsylvania Hospital Philadelphia, Pennsylvania | Site Public Contact - (PMCancerResearch@pennmedicine.upenn.edu) |
| Penrose-Saint Francis Healthcare Colorado Springs, Colorado | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Phelps Health Delbert Day Cancer Institute Rolla, Missouri | Site Public Contact - (research@phelpshealth.org) |
| Phelps Memorial Hospital Center Sleepy Hollow, New York | |
| Phoebe Putney Memorial Hospital Albany, Georgia | Site Public Contact - (ga_cares@augusta.edu) |
| Physicians' Clinic of Iowa PC Cedar Rapids, Iowa | |
| Piedmont Fayette Hospital Fayetteville, Georgia | |
| Piedmont Henry Hospital Stockbridge, Georgia | |
| Piedmont Hospital Atlanta, Georgia | |
| Piedmont Newnan Hospital Newnan, Georgia | |
| Pocono Medical Center East Stroudsburg, Pennsylvania | Site Public Contact - (Morgan_M.Horton@lvhn.org) |
| Poudre Valley Hospital Fort Collins, Colorado | |
| Premier Blood and Cancer Center Dayton, Ohio | |
| Presbyterian Kaseman Hospital Albuquerque, New Mexico | Site Public Contact - (WBurman@phs.org) |
| Presbyterian Rust Medical Center/Jorgensen Cancer Center Rio Rancho, New Mexico | Site Public Contact - (WBurman@phs.org) |
| Prisma Health Cancer Institute - Butternut Greenville, South Carolina | Site Public Contact - (Kim.Williams3@prismahealth.org) |
| Prisma Health Cancer Institute - Easley Easley, South Carolina | Site Public Contact - (Kim.Williams3@prismahealth.org) |
| Prisma Health Cancer Institute - Eastside Greenville, South Carolina | Site Public Contact - (Kim.Williams3@prismahealth.org) |
| Prisma Health Cancer Institute - Faris Greenville, South Carolina | Site Public Contact - (Kim.Williams3@prismahealth.org) |
| Prisma Health Cancer Institute - Greer Greer, South Carolina | Site Public Contact - (Kim.Williams3@prismahealth.org) |
| Prisma Health Cancer Institute - Seneca Seneca, South Carolina | Site Public Contact - (Kim.Williams3@prismahealth.org) |
| Prisma Health Cancer Institute - Spartanburg Boiling Springs, South Carolina | Site Public Contact - (Kim.Williams3@prismahealth.org) |
| ProHealth D N Greenwald Center Mukwonago, Wisconsin | |
| ProHealth Oconomowoc Memorial Hospital Oconomowoc, Wisconsin | |
| ProMedica Flower Hospital Sylvania, Ohio | Site Public Contact - (PCIOncResearch@promedica.org) |
| ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital Toledo, Ohio | Site Public Contact - (PCIOncResearch@promedica.org) |
| Providence Cancer Institute Clackamas Clinic Clackamas, Oregon | |
| Providence Hood River Memorial Hospital Hood River, Oregon | Site Public Contact - (canrsrchstudies@provdience.org) |
| Providence Newberg Medical Center Newberg, Oregon | Site Public Contact - (CanRsrchStudies@providence.org) |
| Providence Portland Medical Center Portland, Oregon | Site Public Contact - (CanRsrchStudies@providence.org) |
| Providence Saint Vincent Medical Center Portland, Oregon | Site Public Contact - (CanRsrchStudies@providence.org) |
| Providence Willamette Falls Medical Center Oregon City, Oregon | Site Public Contact - (CanRsrchStudies@providence.org) |
| Queen's Cancer Cenrer - POB I Honolulu, Hawaii | |
| Queen's Cancer Center - Kuakini Honolulu, Hawaii | |
| Queen's Medical Center Honolulu, Hawaii | |
| Queens Cancer Center Rego Park, New York | |
| Rapid City Regional Hospital Rapid City, South Dakota | Site Public Contact - (research@monument.health) |
| Reading Hospital West Reading, Pennsylvania | |
| Reading Hospital McGlinn Cancer Institute at Phoenixville Phoenixville, Pennsylvania | |
| Regions Hospital Saint Paul, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Reid Health Richmond, Indiana | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Reiman Cancer Center-Ascension Wisconsin Health Center-Rawson Franklin, Wisconsin | Site Public Contact - (AWRI.Inquiry@Ascension.org) |
| Renown Regional Medical Center Reno, Nevada | Site Public Contact - (Renown-CRD@renown.org) |
| Rice Memorial Hospital Willmar, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Ridgeview Medical Center Waconia, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Ridley-Tree Cancer Center Santa Barbara, California | Site Public Contact - (clinicalresearch@sutterhealth.org) |
| Riverside Methodist Hospital Columbus, Ohio | |
| Riverton Hospital Riverton, Utah | Site Public Contact - (officeofresearch@imail.org) |
| Robert Wood Johnson University Hospital Somerset Somerville, New Jersey | Site Public Contact - (Siby.Varughese@rwjbh.org) |
| Rochester General Hospital Rochester, New York | Site Public Contact - (tia.derosa@rochestergeneral.org) |
| Rocky Mountain Cancer Centers-Longmont Longmont, Colorado | |
| Rocky Mountain Cancer Centers-Penrose Colorado Springs, Colorado | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Roger Williams Medical Center Providence, Rhode Island | Site Public Contact - (fdallesandro@chartercare.org) |
| Roper Hospital Charleston, South Carolina | |
| Royal Victoria Regional Health Centre Barrie, Ontario | |
| Rush MD Anderson Cancer Center Chicago, Illinois | Site Public Contact - (Cancer_Studies@rush.edu) |
| Rush MD Anderson Cancer Center at Rush Lisle Lisle, Illinois | Site Public Contact - (Cancer_Studies@rush.edu) |
| Rush MD Anderson Cancer Center at Rush Oak Park Oak Park, Illinois | Site Public Contact - (Cancer_Studies@rush.edu) |
| Rush-Copley Healthcare Center Yorkville, Illinois | Site Public Contact - (Cancer.Research@rushcopley.com) |
| Rush-Copley Medical Center Aurora, Illinois | Site Public Contact - (RCMC_Cancer_Research@rush.edu) |
| Rutgers Cancer Institute of New Jersey New Brunswick, New Jersey | |
| Rutgers New Jersey Medical School Newark, New Jersey | |
| SIH Cancer Institute Carterville, Illinois | Site Public Contact - (clinical.research@sih.net) |
| SMC Center for Hematology Oncology Union Union, South Carolina | Site Public Contact - (kmertz-rivera@gibbscc.org) |
| SSM Health Good Samaritan Mount Vernon, Illinois | Site Public Contact - (gayla.hall@ssmhealth.com) |
| STCC at DHR Health Institute for Research and Development Edinburg, Texas | Site Public Contact - (dhrresearch@dhr-rgv.com) |
| Saddleback Memorial Medical Center Laguna Hills, California | |
| Saint Agnes Hospital Baltimore, Maryland | |
| Saint Alphonsus Cancer Care Center-Boise Boise, Idaho | Site Public Contact - (stephanie.couch@stjoeshealth.org) |
| Saint Alphonsus Cancer Care Center-Caldwell Caldwell, Idaho | Site Public Contact - (stephanie.couch@stjoeshealth.org) |
| Saint Alphonsus Cancer Care Center-Nampa Nampa, Idaho | Site Public Contact - (mccinfo@mtcancer.org) |
| Saint Alphonsus Cancer Care Center-Ontario Ontario, Oregon | Site Public Contact - (mccinfo@mtcancer.org) |
| Saint Ann's Hospital Westerville, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Saint Anthony Regional Hospital Carroll, Iowa | Site Public Contact - (sbenson@iora.org) |
| Saint Anthony's Hospital Cancer Care Center St. Petersburg, Florida | Site Public Contact - (Research.CTO@baycare.org) |
| Saint Catherine Hospital Indianapolis, Indiana | Site Public Contact - (Roster@nrgoncology.org) |
| Saint Clare Hospital Lakewood, Washington | |
| Saint Elizabeth Boardman Hospital Boardman, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Saint Elizabeth Hospital Enumclaw, Washington | |
| Saint Elizabeth Regional Medical Center Lincoln, Nebraska | |
| Saint Elizabeth Youngstown Hospital Youngstown, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Saint Francis Cancer Center Greenville, South Carolina | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Saint Francis Hospital Greenville, South Carolina | |
| Saint Francis Medical Center Cape Girardeau, Missouri | Site Public Contact - (sfmc@sfmc.net) |
| Saint Francis Regional Medical Center Shakopee, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Saint George Regional Medical Center St. George, Utah | Site Public Contact - (officeofresearch@imail.org) |
| Saint John's Hospital - Healtheast Maplewood, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Saint Joseph Hospital - Cancer Centers of Colorado Denver, Colorado | |
| Saint Joseph Hospital - Orange Orange, California | |
| Saint Joseph Medical Center Hematology and Oncology - Silverdale Silverdale, Washington | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Saint Joseph Radiation Oncology Resource Center Lexington, Kentucky | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Saint Joseph Regional Cancer Center Bryan, Texas | |
| Saint Joseph Warren Hospital Warren, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Saint Joseph's Hospital/Children's Hospital-Tampa Tampa, Florida | Site Public Contact - (jennifer.manns@baycare.org) |
| Saint Luke's Cancer Institute - Boise Boise, Idaho | Site Public Contact - (eslinget@slhs.org) |
| Saint Luke's Cancer Institute - Fruitland Fruitland, Idaho | Site Public Contact - (eslinget@slhs.org) |
| Saint Luke's Cancer Institute - Meridian Meridian, Idaho | Site Public Contact - (eslinget@slhs.org) |
| Saint Luke's Cancer Institute - Nampa Nampa, Idaho | Site Public Contact - (eslinget@slhs.org) |
| Saint Luke's East - Lee's Summit Lee's Summit, Missouri | Site Public Contact - (aroland@kccop.org) |
| Saint Luke's Hospital of Kansas City Kansas City, Missouri | Site Public Contact - (aroland@kccop.org) |
| Saint Luke's South Hospital Overland Park, Kansas | Site Public Contact - (aroland@kccop.org) |
| Saint Mary Corwin Medical Center Pueblo, Colorado | Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org) |
| Saint Mary Medical Center Hobart, Indiana | Site Public Contact - (CancerResearch@COMHS.org) |
| Saint Mary's Hospital and Regional Medical Center Grand Junction, Colorado | Site Public Contact - (ccrp@co-cancerresearch.org) |
| Saint Mary's Oncology/Hematology Associates of Marlette Marlette, Michigan | |
| Saint Mary's Oncology/Hematology Associates of West Branch West Branch, Michigan | |
| Saint Mary's Regional Medical Center Reno, Nevada | Site Public Contact - (research@sncrf.org) |
| Saint Michael's Hospital Stevens Point, Wisconsin | |
| Saint Rita's Medical Center Lima, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Saint Vincent Frontier Cancer Center Billings, Montana | |
| Saint Vincent Hospital Erie, Pennsylvania | |
| Saint Vincent Hospital Cancer Center Green Bay Green Bay, Wisconsin | Site Public Contact - (WI_research_admin@hshs.org) |
| Saint Vincent Hospital Cancer Center at Oconto Falls Oconto Falls, Wisconsin | Site Public Contact - (WI_research_admin@hshs.org) |
| Saint Vincent Hospital Cancer Center at Saint Mary's Green Bay, Wisconsin | Site Public Contact - (wi_research_admin@hshs.org) |
| Saint Vincent Hospital Cancer Center at Sturgeon Bay Sturgeon Bay, Wisconsin | Site Public Contact - (wi_research_admin@hshs.org) |
| Sainte Genevieve County Memorial Hospital Sainte Genevieve, Missouri | |
| Saints Mary and Elizabeth Hospital Louisville, Kentucky | |
| Salinas Valley Memorial Salinas, California | Site Public Contact - (tnielsen2@svmh.com) |
| San Juan City Hospital San Juan, | |
| Sandra L Maxwell Cancer Center Cedar City, Utah | Site Public Contact - (officeofresearch@imail.org) |
| Sanford Bismarck Medical Center Bismarck, North Dakota | Site Public Contact - (OncologyClinicalTrialsFargo@sanfordhealth.org) |
| Sanford Broadway Medical Center Fargo, North Dakota | Site Public Contact - (OncologyClinicalTrialsFargo@sanfordhealth.org) |
| Sanford Cancer Center Oncology Clinic Sioux Falls, South Dakota | Site Public Contact - (OncologyClinicTrialsSF@sanfordhealth.org) |
| Sanford Cancer Center Worthington Worthington, Minnesota | |
| Sanford Joe Lueken Cancer Center Bemidji, Minnesota | Site Public Contact - (OncologyClinicalTrialsFargo@sanfordhealth.org) |
| Sanford Roger Maris Cancer Center Fargo, North Dakota | Site Public Contact - (OncologyClinicalTrialsFargo@sanfordhealth.org) |
| Sanford Thief River Falls Medical Center Thief River Falls, Minnesota | |
| Sanford USD Medical Center - Sioux Falls Sioux Falls, South Dakota | Site Public Contact - (OncologyClinicalTrialsSF@SanfordHealth.org) |
| Santa Cruz Radiation Oncology Medical Group Santa Cruz, California | Site Public Contact - (clinicalresearch@sutterhealth.org) |
| Saskatoon Cancer Centre Saskatoon, Saskatchewan | |
| Scott and White Memorial Hospital Temple, Texas | |
| Sechler Family Cancer Center Lebanon, Pennsylvania | Site Public Contact - (doxenberg@wellspan.org) |
| Shaw Cancer Center Edwards, Colorado | |
| Sheboygan Physicians Group Sheboygan, Wisconsin | Site Public Contact - (wi_research_admin@hshs.org) |
| Sidney Kimmel Cancer Center Washington Township Sewell, New Jersey | Site Public Contact - (ONCTrialNow@jefferson.edu) |
| Sinai Hospital of Baltimore Baltimore, Maryland | |
| Siouxland Regional Cancer Center Sioux City, Iowa | |
| Siteman Cancer Center at Christian Hospital St Louis, Missouri | Site Public Contact - (info@siteman.wustl.edu) |
| Siteman Cancer Center at Saint Peters Hospital City of Saint Peters, Missouri | Site Public Contact - (info@siteman.wustl.edu) |
| Siteman Cancer Center at West County Hospital Creve Coeur, Missouri | Site Public Contact - (info@siteman.wustl.edu) |
| Siteman Cancer Center-South County St Louis, Missouri | Site Public Contact - (info@siteman.wustl.edu) |
| Smilow Cancer Center/Yale-New Haven Hospital New Haven, Connecticut | Site Public Contact - (canceranswers@yale.edu) |
| Smilow Cancer Hospital Care Center - Guilford Guilford, Connecticut | Site Public Contact - (canceranswers@yale.edu) |
| Smilow Cancer Hospital Care Center - Waterford Waterford, Connecticut | Site Public Contact - (canceranswers@yale.edu) |
| Smilow Cancer Hospital Care Center - Westerly Westerly, Rhode Island | Site Public Contact - (canceranswers@yale.edu) |
| Smilow Cancer Hospital Care Center at Glastonbury Glastonbury, Connecticut | Site Public Contact - (canceranswers@yale.edu) |
| Smilow Cancer Hospital Care Center at Greenwich Greenwich, Connecticut | Site Public Contact - (canceranswers@yale.edu) |
| Smilow Cancer Hospital Care Center at Long Ridge Stamford, Connecticut | Site Public Contact - (canceranswers@yale.edu) |
| Smilow Cancer Hospital Care Center at Saint Francis Hartford, Connecticut | Site Public Contact - (canceranswers@yale.edu) |
| Smilow Cancer Hospital Care Center-Fairfield Fairfield, Connecticut | Site Public Contact - (canceranswers@yale.edu) |
| Smilow Cancer Hospital Care Center-Trumbull Trumbull, Connecticut | Site Public Contact - (canceranswers@yale.edu) |
| Smilow Cancer Hospital-Derby Care Center Derby, Connecticut | Site Public Contact - (canceranswers@yale.edu) |
| Smilow Cancer Hospital-Orange Care Center Orange, Connecticut | Site Public Contact - (canceranswers@yale.edu) |
| Smilow Cancer Hospital-Torrington Care Center Torrington, Connecticut | Site Public Contact - (canceranswers@yale.edu) |
| Smilow Cancer Hospital-Waterbury Care Center Waterbury, Connecticut | Site Public Contact - (canceranswers@yale.edu) |
| Solinsky Center for Cancer Care Manchester, New Hampshire | |
| South Florida Baptist Hospital Plant City, Florida | Site Public Contact - (Claudia.Quinones@baycare.org) |
| South Jordan Health Center South Jordan, Utah | Site Public Contact - (cancerinfo@hci.utah.edu) |
| South Pointe Hospital Warrensville Heights, Ohio | Site Public Contact - (TaussigResearch@ccf.org) |
| Southeastern Medical Oncology Center-Clinton Clinton, North Carolina | Site Public Contact - (jfields@cancersmoc.com) |
| Southeastern Medical Oncology Center-Goldsboro Goldsboro, North Carolina | Site Public Contact - (jfields@cancersmoc.com) |
| Southeastern Medical Oncology Center-Jacksonville Jacksonville, North Carolina | Site Public Contact - (jfields@cancersmoc.com) |
| Southern Illinois University School of Medicine Springfield, Illinois | |
| Southern Ohio Medical Center Portsmouth, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Spartanburg Medical Center Spartanburg, South Carolina | Site Public Contact - (kmertz-rivera@gibbscc.org) |
| Springfield Clinic Springfield, Illinois | |
| Springfield Memorial Hospital Springfield, Illinois | Site Public Contact - (pallante.beth@mhsil.com) |
| Springfield Regional Cancer Center Springfield, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Springfield Regional Medical Center Springfield, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Staten Island University Hospital Staten Island, New York | |
| Stony Brook University Medical Center Stony Brook, New York | |
| Straub Clinic and Hospital Honolulu, Hawaii | |
| Strecker Cancer Center-Belpre Belpre, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Stronach Regional Health Centre at Southlake Newmarket, Ontario | |
| Summa Health Medina Medical Center Medina, Ohio | Site Public Contact - (cancerresearch@summahealth.org) |
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| Summa Health System - Barberton Campus Barberton, Ohio | Site Public Contact - (cancerresearch@summahealth.org) |
| Summit Health - Florham Park Campus Florham Park, New Jersey | |
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| Swedish Covenant Hospital Chicago, Illinois | |
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| Tampa General Hospital Tampa, Florida | Site Public Contact - (syapchanyk@tgh.org) |
| The Cancer Institute of New Jersey Hamilton Hamilton, New Jersey | |
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| The Community Hospital Munster, Indiana | |
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| The Don and Sybil Harrington Cancer Center Amarillo, Texas | Site Public Contact - (Gina.Cravey@bsahs.org) |
| The James Graham Brown Cancer Center at University of Louisville Louisville, Kentucky | |
| The Mark H Zangmeister Center Columbus, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| The New York Hospital Medical Center of Queens Flushing, New York | Site Public Contact - (Roster@nrgoncology.org) |
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| The Valley Hospital - Luckow Pavilion Paramus, New Jersey | Site Public Contact - (clinicaltrialsresearch@valleyhealth.com) |
| The Watson Clinic Lakeland, Florida | |
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| ThedaCare Cancer Care - Waupaca Waupaca, Wisconsin | Site Public Contact - (ResearchDept@thedacare.org) |
| ThedaCare Regional Cancer Center Appleton, Wisconsin | Site Public Contact - (ResearchDept@thedacare.org) |
| ThedaCare Regional Medical Center - Neenah Neenah, Wisconsin | Site Public Contact - (ResearchDept@thedacare.org) |
| Thomas Hospital Fairhope, Alabama | |
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| Torrance Memorial Physician Network - Cancer Care Torrance, California | Site Public Contact - (courtney.steeneken@tmphysicians.com) |
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| Trinitas Hospital and Comprehensive Cancer Center - Williamson Street Campus Elizabeth, New Jersey | |
| Trinity Health Grand Rapids Hospital Grand Rapids, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
| Trinity Health IHA Medical Group Hematology Oncology - Brighton Brighton, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Trinity Health IHA Medical Group Hematology Oncology - Canton Canton, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital Chelsea, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus Ypsilanti, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
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| Trinity Health Saint Mary Mercy Livonia Hospital Livonia, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Trinity Medical Center Moline, Illinois | |
| Trinity's Tony Teramana Cancer Center Steubenville, Ohio | |
| Tufts Medical Center Boston, Massachusetts | Site Public Contact - (ContactUsCancerCenter@TuftsMedicalCenter.org) |
| UC Comprehensive Cancer Center at Silver Cross New Lenox, Illinois | Site Public Contact - (cancerclinicaltrials@bsd.uchicago.edu) |
| UC Irvine Health/Chao Family Comprehensive Cancer Center Orange, California | Site Public Contact - (ucstudy@uci.edu) |
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| UCHealth - Cherry Creek Denver, Colorado | Site Public Contact - (Roster@nrgoncology.org) |
| UCHealth Greeley Hospital Greeley, Colorado | Site Public Contact - (Roster@nrgoncology.org) |
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| UChicago Medicine AdventHealth Cancer Institute Hinsdale Hinsdale, Illinois | Site Public Contact - (cancerclinicaltrials@bsd.uchicago.edu) |
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| UH Seidman Cancer Center at Lake Health Mentor Campus Mentor, Ohio | |
| UH Seidman Cancer Center at Saint John Medical Center Westlake, Ohio | |
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| UH Seidman Cancer Center at UH Avon Health Center Avon, Ohio | |
| UHHS-Chagrin Highlands Medical Center Beachwood, Ohio | |
| UI Health Care Mission Cancer and Blood - Ankeny Clinic Ankeny, Iowa | |
| UI Health Care Mission Cancer and Blood - Des Moines Clinic Des Moines, Iowa | |
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| UI Health Care Mission Cancer and Blood - Waukee Clinic Waukee, Iowa | |
| UI Health Care Mission Cancer and Blood - West Des Moines Clinic Clive, Iowa | |
| UM Baltimore Washington Medical Center/Tate Cancer Center Glen Burnie, Maryland | |
| UM Upper Chesapeake Hematology and Oncology - Aberdeen Aberdeen, Maryland | Site Public Contact - (nfadrwoski@umm.edu) |
| UM Upper Chesapeake Medical Center Bel Air, Maryland | |
| UNC Health Cancer Care Cary Cary, North Carolina | Site Public Contact - (CancCtrOncologyClinicalResearch@unchealth.unc.edu) |
| UNC Health Cancer Care Garner Garner, North Carolina | Site Public Contact - (CancCtrOncologyClinicalResearch@unchealth.unc.edu) |
| UNC Health Cancer Care Raleigh Raleigh, North Carolina | Site Public Contact - (CancCtrOncologyClinicalResearch@unchealth.unc.edu) |
| UNC Health Cancer Care Wakefield Raleigh, North Carolina | Site Public Contact - (CancCtrOncologyClinicalResearch@unchealth.unc.edu) |
| UNC Lineberger Comprehensive Cancer Center Chapel Hill, North Carolina | Site Public Contact - (cancerclinicaltrials@med.unc.edu) |
| UPMC Altoona Altoona, Pennsylvania | Site Public Contact - (Roster@nrgoncology.org) |
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| UPMC Cancer Center at UPMC Northwest Seneca, Pennsylvania | |
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| UPMC Hillman Cancer Center - New Castle New Castle, Pennsylvania | Site Public Contact - (haneydl@upmc.edu) |
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| UPMC-Johnstown/John P. Murtha Regional Cancer Center Johnstown, Pennsylvania | |
| UPMC-Mercy Hospital Pittsburgh, Pennsylvania | |
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| UPMC-Saint Clair Hospital Cancer Center Pittsburgh, Pennsylvania | |
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| USC / Norris Comprehensive Cancer Center Los Angeles, California | |
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| UT MD Anderson - League City League City, Texas | Site Public Contact - (askmdanderson@mdanderson.org) |
| UT MD Anderson - Sugar Land Sugar Land, Texas | Site Public Contact - (askmdanderson@mdanderson.org) |
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| University of Cincinnati Cancer Center-UC Medical Center Cincinnati, Ohio | Site Public Contact - (cancer@uchealth.com) |
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| University of Hawaii Cancer Center Honolulu, Hawaii | |
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| University of Michigan Rogel Cancer Center Ann Arbor, Michigan | Site Public Contact - (CancerAnswerLine@med.umich.edu) |
| University of Mississippi Medical Center Jackson, Mississippi | |
| University of New Mexico Cancer Center Albuquerque, New Mexico | Site Public Contact - (HSC-ClinicalTrialInfo@salud.unm.edu) |
| University of Oklahoma Health Sciences Center Oklahoma City, Oklahoma | Site Public Contact - (ou-clinical-trials@ouhsc.edu) |
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| University of Washington Medical Center - Montlake Seattle, Washington | |
| University of Wisconsin Carbone Cancer Center - Eastpark Medical Center Madison, Wisconsin | Site Public Contact - (clinicaltrials@cancer.wisc.edu) |
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| Yale University New Haven, Connecticut | Site Public Contact - (canceranswers@yale.edu) |
| Yale-New Haven Hospital North Haven Medical Center North Haven, Connecticut | Site Public Contact - (canceranswers@yale.edu) |
Collection of Research Data and Samples From Patients Treated With Immunotherapy to Study Its Side Effects
David Kozono, MD, PhD - dkozono@bwh.harvard.edu
NCT04242095
Show full eligibility criteria
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* PRE-REGISTRATION ELIGIBILITY CRITERIA: Planning to receive a regimen containing one or more IO therapeutics
* PRE-REGISTRATION ELIGIBILITY CRITERIA: Has not previously been treated with CTLA-4, PD-1 or PD-L1 inhibitors
* PRE-REGISTRATION ELIGIBILITY CRITERIA: Willing and able to provide baseline blood and stool samples
* REGISTRATION ELIGIBILITY CRITERIA: Received a regimen containing one or more immuno-oncology therapeutics
* Must have received one or more IO therapeutics
* In addition to one or more IO therapeutics, patients may also have received other therapeutics such as chemotherapy, hormonal or targeted therapy, as long as these are reported
* REGISTRATION ELIGIBILITY CRITERIA: Must have experienced one or more of the following:
* One or more serious (grade 3-54) AEs that are likely immune-related. AEs included in Common Terminology Criteria for Adverse Events (CTCAE) version (v.) 5.0 that may be immune-related
\*\* Patients who experience only hematologic cytopenia(s) who have received cytotoxic therapies, e.g., chemotherapy, within 60 days prior to registration should be excluded
* One or more grade 2 dermatologic, endocrine (except diabetes/hyperglycemia) or rheumatologic AEs that are likely immune-related. AEs included in CTCAE v. 5.0 that may be immune-related
* Diagnosis of a rare infection, e.g., fungal or mycobacterial, after starting IO treatment
\*\* Note: Diagnosis of SARS-CoV-2 (COVID-19) is excluded
* Hyperprogression. Image submission for patients experiencing hyperprogression is required. For assistance in determining hyperprogression for purposes of eligibility, institutions may contact the study chair and submit images for central review
* REGISTRATION ELIGIBILITY CRITERIA: Has not previously been registered to this study \* The same patient cannot be enrolled more than once to this study due to development of subsequent irAEs
PROCEDURE: Biospecimen Collection, OTHER: Medical Chart Review
Hematopoietic and Lymphoid Cell Neoplasm, Immune System Disorder, Malignant Solid Neoplasm
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Study Locations
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| Location | Contacts |
|---|---|
| AMG Crystal Lake - Oncology Crystal Lake, Illinois | Site Public Contact - (advocateresearch@advocate.com) |
| AMG Libertyville - Oncology Libertyville, Illinois | Site Public Contact - (advocateresearch@advocatehealth.com) |
| Abbott-Northwestern Hospital Minneapolis, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Adams Cancer Center Gettysburg, Pennsylvania | |
| Adena Regional Medical Center Chillicothe, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Advanced Breast Care Center PLLC Warren, Michigan | |
| AdventHealth Littleton Littleton, Colorado | |
| AdventHealth Parker Parker, Colorado | |
| AdventHealth Porter Denver, Colorado | |
| Advocate Christ Medical Center Oak Lawn, Illinois | |
| Advocate Good Samaritan Hospital Downers Grove, Illinois | Site Public Contact - (Barbara.barhamand@advocatehealth.com) |
| Advocate Good Shepherd Hospital Barrington, Illinois | |
| Advocate Illinois Masonic Medical Center Chicago, Illinois | |
| Advocate Lutheran General Hospital Park Ridge, Illinois | |
| Advocate Outpatient Center - Aurora Aurora, Illinois | Site Public Contact - (ncorp@aah.org) |
| Advocate Sherman Hospital Elgin, Illinois | |
| Advocate South Suburban Hospital Hazel Crest, Illinois | |
| Alaska Breast Care and Surgery LLC Anchorage, Alaska | Site Public Contact - (AKPAMC.OncologyResearchSupport@providence.org) |
| Alaska Oncology and Hematology LLC Anchorage, Alaska | Site Public Contact - (AKPAMC.OncologyResearchSupport@providence.org) |
| Alaska Women's Cancer Care Anchorage, Alaska | Site Public Contact - (AKPAMC.OncologyResearchSupport@providence.org) |
| Alegent Health Bergan Mercy Medical Center Omaha, Nebraska | |
| Alegent Health Immanuel Medical Center Omaha, Nebraska | |
| Alegent Health Lakeside Hospital Omaha, Nebraska | |
| Alegent Health Mercy Hospital Council Bluffs, Iowa | |
| Alliance for Childhood Diseases/Cure 4 the Kids Foundation Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Anchorage Associates in Radiation Medicine Anchorage, Alaska | Site Public Contact - (AKPAMC.OncologyResearchSupport@providence.org) |
| Anchorage Oncology Centre Anchorage, Alaska | |
| Anchorage Radiation Therapy Center Anchorage, Alaska | |
| Ann M Wierman MD LTD Las Vegas, Nevada | |
| Armes Family Cancer Center Findlay, Ohio | |
| Ascension All Saints Hospital-Spring Street-Racine Racine, Wisconsin | Site Public Contact - (AWRI.Inquiry@Ascension.org) |
| Ascension Calumet Hospital-Chilton Chilton, Wisconsin | Site Public Contact - (AWRI.inquiry@ascension.org) |
| Ascension Columbia Saint Mary's Hospital-Milwaukee Campus Milwaukee, Wisconsin | Site Public Contact - (AWRI.Inquiry@Ascension.org) |
| Ascension Columbia Saint Mary's Hospital-Ozaukee Campus-Mequon Mequon, Wisconsin | Site Public Contact - (AWRI.Inquiry@Ascension.org) |
| Ascension Northeast Wisconsin-Mercy Hospital-Oshkosh Oshkosh, Wisconsin | Site Public Contact - (AWRI.inquiry@ascension.org) |
| Ascension Northeast Wisconsin-Saint Elizabeth Cancer Center-Appleton Appleton, Wisconsin | Site Public Contact - (AWRI.inquiry@ascension.org) |
| Ascension Saint Francis Hospital-Milwaukee Milwaukee, Wisconsin | Site Public Contact - (AWRI.Inquiry@Ascension.org) |
| Ascension Southeast Wisconsin Hospital - Franklin Franklin, Wisconsin | Site Public Contact - (AWRI.Inquiry@Ascension.org) |
| Ascension Southeast Wisconsin Hospital-Elmbrook Campus-Brookfield Brookfield, Wisconsin | Site Public Contact - (AWRI.Inquiry@Ascension.org) |
| Ascension Southeast Wisconsin Hospital-Mayfair Road-Wauwatosa Wauwatosa, Wisconsin | Site Public Contact - (AWRI.Inquiry@Ascension.org) |
| Ascension Southeast Wisconsin Hospital-Saint Joseph-Milwaukee Milwaukee, Wisconsin | Site Public Contact - (AWRI.Inquiry@Ascension.org) |
| Aspirus Cancer Care - Stevens Point Stevens Point, Wisconsin | |
| Aspirus Cancer Care-Rhinelander-James Beck Cancer Center Rhinelander, Wisconsin | |
| Atrium Medical Center-Middletown Regional Hospital Franklin, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Audie L Murphy VA Hospital San Antonio, Texas | |
| Aurora Bay Area Medical Group-Marinette Marinette, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora BayCare Medical Center Green Bay, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Cancer Care-Grafton Grafton, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Cancer Care-Kenosha South Kenosha, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Cancer Care-Milwaukee Milwaukee, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Cancer Care-Milwaukee West Wauwatosa, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Cancer Care-Racine Racine, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Cancer Care-Southern Lakes VLCC Burlington, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Health Care Germantown Health Center Germantown, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Medical Center in Summit Summit, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Saint Luke's Medical Center Milwaukee, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Saint Luke's South Shore Cudahy, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Sinai Medical Center Milwaukee, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora West Allis Medical Center West Allis, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Avera Cancer Institute Sioux Falls, South Dakota | Site Public Contact - (OncRegulatory@avera.org) |
| BASS Medical Group - Lennon Walnut Creek, California | |
| Bay Area Breast Surgeons Inc Emeryville, California | |
| Bay Area Hospital Coos Bay, Oregon | |
| Bay Area Tumor Institute Oakland, California | |
| Beebe Health Campus Rehoboth Beach, Delaware | Site Public Contact - (research@beebehealthcare.org) |
| Beebe Medical Center Lewes, Delaware | Site Public Contact - (research@beebehealthcare.org) |
| Beebe South Coastal Health Campus Millville, Delaware | Site Public Contact - (research@beebehealthcare.org) |
| Benefis Helena Specialty Center Helena, Montana | Site Public Contact - (mccinfo@mtcancer.org) |
| Benefis Sletten Cancer Institute Great Falls, Montana | Site Public Contact - (mccinfo@mtcancer.org) |
| Beth Israel Deaconess Medical Center Boston, Massachusetts | |
| Bethesda North Hospital Cincinnati, Ohio | |
| Bhadresh Nayak MD PC-Sterling Heights Sterling Heights, Michigan | |
| Billings Clinic Cancer Center Billings, Montana | Site Public Contact - (research@billingsclinic.org) |
| Billings Clinic-Cody Cody, Wyoming | Site Public Contact - (research@billingsclinic.org) |
| Blanchard Valley Hospital Findlay, Ohio | |
| Boulder Community Foothills Hospital Boulder, Colorado | |
| Bozeman Health Deaconess Hospital Bozeman, Montana | Site Public Contact - (mccinfo@mtcancer.org) |
| Brigham and Women's Hospital Boston, Massachusetts | |
| Broadlawns Medical Center Des Moines, Iowa | |
| CARTI Cancer center Little Rock, Arkansas | Site Public Contact - (Research@CARTI.com) |
| CHI Health Good Samaritan Kearney, Nebraska | |
| CHI Health Saint Francis Grand Island, Nebraska | |
| CHI Saint Vincent Cancer Center Hot Springs Hot Springs, Arkansas | |
| Cambridge Medical Center Cambridge, Minnesota | |
| Camden Clark Medical Center Parkersburg, West Virginia | Site Public Contact - (cancertrialsinfo@hsc.wvu.edu) |
| Cancer Care Associates of York York, Pennsylvania | |
| Cancer Care Center of O'Fallon O'Fallon, Illinois | |
| Cancer Care Northwest - Spokane South Spokane, Washington | Site Public Contact - (research@ccnw.net) |
| Cancer Care Northwest-North Spokane Spokane, Washington | Site Public Contact - (research@ccnw.net) |
| Cancer Care Northwest-Valley Spokane, Washington | Site Public Contact - (research@ccnw.net) |
| Cancer Care Specialists of Illinois - Decatur Decatur, Illinois | Site Public Contact - (morganthaler.jodi@mhsil.com) |
| Cancer Center at Saint Joseph's Phoenix, Arizona | |
| Cancer Center of Western Wisconsin New Richmond, Wisconsin | Site Public Contact - (mmcorc@healthpartners.com) |
| Cancer Hematology Centers - Flint Flint, Michigan | Site Public Contact - (wstrong@ghci.org) |
| Cancer and Blood Specialists-Henderson Henderson, Nevada | |
| Cancer and Blood Specialists-Shadow Las Vegas, Nevada | |
| Cancer and Blood Specialists-Tenaya Las Vegas, Nevada | |
| Cancer and Hematology Centers of Western Michigan - Norton Shores Norton Shores, Michigan | Site Public Contact - (connie.szczepanek@crcwm.org) |
| Carle BroMenn Medical Center Normal, Illinois | Site Public Contact - (Research@Carle.com) |
| Carle Cancer Center Urbana, Illinois | Site Public Contact - (Research@carle.com) |
| Carle Cancer Institute Normal Normal, Illinois | Site Public Contact - (Research@Carle.com) |
| Carle Physician Group-Effingham Effingham, Illinois | Site Public Contact - (Research@carle.com) |
| Carle Physician Group-Mattoon/Charleston Mattoon, Illinois | Site Public Contact - (Research@carle.com) |
| Carle at The Riverfront Danville, Illinois | Site Public Contact - (Research@Carle.com) |
| Caro Cancer Center Caro, Michigan | |
| CaroMont Regional Medical Center Gastonia, North Carolina | |
| Carson Tahoe Regional Medical Center Carson City, Nevada | Site Public Contact - (research@sncrf.org) |
| Central Care Cancer Center - Bolivar Bolivar, Missouri | Site Public Contact - (aroland@kccop.org) |
| Central Care Cancer Center - Garden City Garden City, Kansas | Site Public Contact - (aroland@kccop.org) |
| Central Care Cancer Center - Great Bend Great Bend, Kansas | Site Public Contact - (aroland@kccop.org) |
| Central Ohio Breast and Endocrine Surgery Gahanna, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Centralia Oncology Clinic Centralia, Illinois | Site Public Contact - (morganthaler.jodi@mhsil.com) |
| Chambersburg Hospital Chambersburg, Pennsylvania | Site Public Contact - (protocols@AllianceNCTN.org) |
| Chelsea Hospital Chelsea, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Christiana Care - Union Hospital Elkton, Maryland | Site Public Contact - (frank.crum@christianacare.org) |
| Christiana Care Health System-Christiana Hospital Newark, Delaware | Site Public Contact - (lbarone@christianacare.org) |
| Christiana Care Health System-Concord Health Center Chadds Ford, Pennsylvania | Site Public Contact - (lbarone@christianacare.org) |
| Christiana Care Health System-Wilmington Hospital Wilmington, Delaware | Site Public Contact - (lbarone@christianacare.org) |
| Cincinnati Children's Hospital Medical Center Cincinnati, Ohio | Site Public Contact - (cancer@cchmc.org) |
| Clackamas Radiation Oncology Center Clackamas, Oregon | Site Public Contact - (CanRsrchStudies@providence.org) |
| Clinton Memorial Hospital/Foster J Boyd Regional Cancer Center Wilmington, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Coborn Cancer Center at Saint Cloud Hospital Saint Cloud, Minnesota | Site Public Contact - (coborncancercenter@centracare.com) |
| Colorado Blood Cancer Institute Denver, Colorado | |
| Columbus Oncology and Hematology Associates Dublin, Ohio | |
| Columbus Oncology and Hematology Associates Inc Columbus, Ohio | |
| CommonSpirit Cancer Center Mercy Durango, Colorado | |
| CommonSpirit Saint Anthony Hospital Cancer Center Lakewood, Colorado | |
| CommonSpirit Saint Joseph Hospital - Bardstown Bardstown, Kentucky | |
| CommonSpirit Saint Joseph Hospital - Lexington Lexington, Kentucky | |
| CommonSpirit Saint Joseph Hospital London London, Kentucky | |
| CommonSpirit Saint Joseph Hospital Mount Sterling Mount Sterling, Kentucky | |
| CommonSpirit Saint Joseph Medical Center - East Lexington Lexington, Kentucky | |
| Commonwealth Cancer Center-Corbin Corbin, Kentucky | |
| Community Hospital of Anaconda Anaconda, Montana | Site Public Contact - (mccinfo@mtcancer.org) |
| Community Medical Center Toms River, New Jersey | Site Public Contact - (mccinfo@mtcancer.org) |
| Comprehensive Cancer Centers of Nevada Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Comprehensive Cancer Centers of Nevada - Central Valley Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Comprehensive Cancer Centers of Nevada - Henderson Henderson, Nevada | Site Public Contact - (research@sncrf.org) |
| Comprehensive Cancer Centers of Nevada - Northwest Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Comprehensive Cancer Centers of Nevada - Town Center Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Comprehensive Cancer Centers of Nevada-Horizon Ridge Henderson, Nevada | Site Public Contact - (research@sncrf.org) |
| Comprehensive Cancer Centers of Nevada-Southeast Henderson Henderson, Nevada | Site Public Contact - (research@sncrf.org) |
| Comprehensive Cancer Centers of Nevada-Summerlin Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Condell Memorial Hospital Libertyville, Illinois | Site Public Contact - (advocateresearch@advocatehealth.com) |
| Contra Costa Regional Medical Center Martinez, California | |
| Cox Cancer Center Branson Branson, Missouri | |
| CoxHealth South Hospital Springfield, Missouri | |
| Crossroads Cancer Center Effingham, Illinois | Site Public Contact - (morganthaler.jodi@mhsil.com) |
| Dana-Farber Cancer Institute Boston, Massachusetts | |
| Dayton Physician LLC - Englewood Dayton, Ohio | |
| Dayton Physicians LLC - Troy Troy, Ohio | |
| Dayton Physicians LLC-Atrium Franklin, Ohio | |
| Dayton Physicians LLC-Miami Valley South Centerville, Ohio | |
| Dayton Physicians LLC-Wayne Greenville, Ohio | |
| Decatur Memorial Hospital Decatur, Illinois | Site Public Contact - (morganthaler.jodi@mhsil.com) |
| Delaware Clinical and Laboratory Physicians PA Newark, Delaware | |
| Delaware Health Center-Grady Cancer Center Delaware, Ohio | |
| Desert West Surgery Las Vegas, Nevada | |
| Doctors Hospital Columbus, Ohio | |
| Dublin Methodist Hospital Dublin, Ohio | |
| Duke Cancer Center Cary Cary, North Carolina | Site Public Contact - (NCTNStudyTeam@dm.duke.edu) |
| Duke Cancer Center Raleigh Raleigh, North Carolina | Site Public Contact - (NCTNStudyTeam@dm.duke.edu) |
| Duke University Medical Center Durham, North Carolina | |
| Duke Women's Cancer Care Raleigh Raleigh, North Carolina | |
| ECU Health Oncology Kenansville Kenansville, North Carolina | |
| ECU Health Oncology Kinston Kinston, North Carolina | |
| ECU Health Oncology Richlands Richlands, North Carolina | |
| East Carolina University Greenville, North Carolina | Site Public Contact - (eubankss@ecu.edu) |
| Englewood Hospital and Medical Center Englewood, New Jersey | |
| Ephrata Cancer Center Ephrata, Pennsylvania | |
| Ephrata Community Hospital Ephrata, Pennsylvania | Site Public Contact - (protocols@AllianceNCTN.org) |
| Epic Care Cyberknife Center Walnut Creek, California | |
| Epic Care Partners in Cancer Care Emeryville, California | |
| Epic Care-Dublin Dublin, California | |
| Fairbanks Memorial Hospital Fairbanks, Alaska | |
| Fairfield Medical Center Lancaster, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Fairview Clinics and Surgery Center Maple Grove Maple Grove, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Fairview Lakes Medical Center Wyoming, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Fairview Northland Medical Center Princeton, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Fairview Ridges Hospital Burnsville, Minnesota | |
| Fairview Southdale Hospital Edina, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| First Dayton Cancer Care Kettering, Ohio | |
| Franciscan Research Center-Northwest Medical Plaza Tacoma, Washington | |
| Fred Hutchinson Cancer Center Seattle, Washington | |
| Freeman Health System Joplin, Missouri | Site Public Contact - (LJCrockett@freemanhealth.com) |
| Geisinger Cancer Services-Pottsville Pottsville, Pennsylvania | Site Public Contact - (cancerresearch@geisinger.edu) |
| Geisinger Medical Center Danville, Pennsylvania | Site Public Contact - (cancerresearch@geisinger.edu) |
| Geisinger Medical Center-Cancer Center Hazleton Hazleton, Pennsylvania | Site Public Contact - (cancerresearch@geisinger.edu) |
| Geisinger Wyoming Valley/Henry Cancer Center Wilkes-Barre, Pennsylvania | Site Public Contact - (HemonCCTrials@geisinger.edu) |
| Genesee Hematology Oncology PC Flint, Michigan | Site Public Contact - (wstrong@ghci.org) |
| Genesis Healthcare System Cancer Care Center Zanesville, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Genesys Hurley Cancer Institute Flint, Michigan | Site Public Contact - (wstrong@ghci.org) |
| Good Samaritan Hospital - Cincinnati Cincinnati, Ohio | |
| Grady Memorial Hospital Delaware, Ohio | |
| Grand Valley Oncology Grand Junction, Colorado | Site Public Contact - (gvoclinicaltrials@gjhosp.org) |
| Grant Medical Center Columbus, Ohio | |
| Great Falls Clinic Great Falls, Montana | Site Public Contact - (mccinfo@mtcancer.org) |
| Greater Dayton Cancer Center Kettering, Ohio | |
| Greater Regional Medical Center Creston, Iowa | |
| Gundersen Lutheran Medical Center La Crosse, Wisconsin | Site Public Contact - (cancerctr@gundersenhealth.org) |
| HSHS Saint Elizabeth's Hospital O'Fallon, Illinois | Site Public Contact - (morganthaler.jodi@mhsil.com) |
| Harrison HealthPartners Hematology and Oncology-Poulsbo Poulsbo, Washington | |
| Health Partners Inc Minneapolis, Minnesota | |
| HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills Las Vegas, Nevada | |
| HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway Las Vegas, Nevada | |
| HealthCare Partners Medical Group Oncology/Hematology-San Martin Las Vegas, Nevada | |
| HealthCare Partners Medical Group Oncology/Hematology-Tenaya Las Vegas, Nevada | |
| Heartland Regional Medical Center Saint Joseph, Missouri | Site Public Contact - (Trisha.England2@mymlc.com) |
| Helen F Graham Cancer Center Newark, Delaware | Site Public Contact - (lbarone@christianacare.org) |
| Hematology Oncology Associates of CNY at Camillus Camillus, New York | |
| Hematology Oncology Associates of Central New York-Auburn Auburn, New York | |
| Hematology Oncology Associates of Central New York-East Syracuse East Syracuse, New York | |
| Hematology Oncology Consultants-Clarkston Clarkston, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Hennepin County Medical Center Minneapolis, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Henry Ford Health Providence Novi Hospital Novi, Michigan | |
| Henry Ford Health Providence Southfield Hospital Southfield, Michigan | |
| Henry Ford Health Saint John Hospital Detroit, Michigan | Site Public Contact - (Kkeenan1@hfhs.org) |
| Henry Ford Health Warren Hospital Warren, Michigan | Site Public Contact - (kforman1@hfhs.org) |
| Henry Ford Madison Heights Hospital - Breast Warren, Michigan | Site Public Contact - (kforman1@hfhs.org) |
| Henry Ford River District Hospital East China Township, Michigan | Site Public Contact - (kforman1@hfhs.org) |
| Henry Ford Rochester Hospital Rochester Hills, Michigan | |
| Henry Ford Saint John Hospital - Academic Grosse Pointe Woods, Michigan | Site Public Contact - (kforman1@hfhs.org) |
| Henry Ford Saint John Hospital - Breast Grosse Pointe Woods, Michigan | Site Public Contact - (karen.forman@ascension.org) |
| Henry Ford Saint John Hospital - Macomb Medical Macomb, Michigan | Site Public Contact - (kforman1@hfhs.org) |
| Henry Ford Saint John Hospital - Van Elslander Grosse Pointe Woods, Michigan | Site Public Contact - (kforman1@hfhs.org) |
| Henry Ford Warren Hospital - Breast Macomb Macomb, Michigan | Site Public Contact - (kforman1@hfhs.org) |
| Henry Ford Warren Hospital - GLCMS Warren, Michigan | Site Public Contact - (kforman1@hfhs.org) |
| Hi-Line Sletten Cancer Center Havre, Montana | Site Public Contact - (protocols@AllianceNCTN.org) |
| Highline Medical Center-Main Campus Burien, Washington | |
| Holy Cross Hospital Fort Lauderdale, Florida | Site Public Contact - (eileen.georgi@holy-cross.com) |
| Hope Cancer Care of Nevada Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Hope Cancer Care of Nevada-Pahrump Pahrump, Nevada | Site Public Contact - (research@sncrf.org) |
| Hope Cancer Center Pontiac, Michigan | |
| Hope Cancer Clinic Livonia, Michigan | |
| Hunterdon Medical Center Flemington, New Jersey | |
| Hurley Medical Center Flint, Michigan | Site Public Contact - (wstrong@ghci.org) |
| Huron Gastroenterology PC Ypsilanti, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Idaho Urologic Institute-Meridian Meridian, Idaho | Site Public Contact - (stephanie.couch@stjoeshealth.org) |
| Illinois CancerCare - Washington Washington, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Bloomington Bloomington, Illinois | |
| Illinois CancerCare-Canton Canton, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Carthage Carthage, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Dixon Dixon, Illinois | |
| Illinois CancerCare-Eureka Eureka, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Galesburg Galesburg, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Kewanee Clinic Kewanee, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Macomb Macomb, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Ottawa Clinic Ottawa, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Pekin Pekin, Illinois | |
| Illinois CancerCare-Peoria Peoria, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Peru Peru, Illinois | |
| Illinois CancerCare-Princeton Princeton, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Indu and Raj Soin Medical Center Beavercreek, Ohio | |
| Iowa Cancer Specialists Davenport, Iowa | |
| Iowa Lutheran Hospital Des Moines, Iowa | |
| Iowa Methodist Medical Center Des Moines, Iowa | |
| Jefferson Healthcare Port Townsend, Washington | |
| Jewish Hospital Louisville, Kentucky | |
| Jewish Hospital Medical Center South Shepherdsville, Kentucky | |
| Kadlec Clinic Hematology and Oncology Kennewick, Washington | Site Public Contact - (research@kadlecmed.org) |
| Katmai Oncology Group Anchorage, Alaska | Site Public Contact - (AKPAMC.OncologyResearchSupport@providence.org) |
| Kettering Medical Center Kettering, Ohio | |
| Kingman Regional Medical Center Kingman, Arizona | Site Public Contact - (research@sncrf.org) |
| Knox Community Hospital Mount Vernon, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Kootenai Clinic Cancer Services - Post Falls Post Falls, Idaho | Site Public Contact - (mccinfo@mtcancer.org) |
| Kootenai Clinic Cancer Services - Sandpoint Sandpoint, Idaho | Site Public Contact - (mccinfo@mtcancer.org) |
| Kootenai Health - Coeur d'Alene Coeur d'Alene, Idaho | Site Public Contact - (mccinfo@mtcancer.org) |
| LSU Health Baton Rouge-North Clinic Baton Rouge, Louisiana | Site Public Contact - (research@ololrmc.com) |
| Lafayette Family Cancer Center-EMMC Brewer, Maine | |
| Lake Regional Hospital Osage Beach, Missouri | Site Public Contact - (clinicaltrials@lakeregional.com) |
| Lakeview Hospital Stillwater, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Las Vegas Cancer Center-Henderson Henderson, Nevada | |
| Las Vegas Cancer Center-Medical Center Las Vegas, Nevada | |
| Las Vegas Prostate Cancer Center Las Vegas, Nevada | |
| Las Vegas Urology - Cathedral Rock Las Vegas, Nevada | |
| Las Vegas Urology - Green Valley Henderson, Nevada | |
| Las Vegas Urology - Pebble Henderson, Nevada | |
| Las Vegas Urology - Pecos Las Vegas, Nevada | |
| Las Vegas Urology - Smoke Ranch Las Vegas, Nevada | |
| Las Vegas Urology - Sunset Las Vegas, Nevada | |
| Lehigh Valley Hospital - Muhlenberg Bethlehem, Pennsylvania | Site Public Contact - (Morgan_M.Horton@lvhn.org) |
| Lehigh Valley Hospital-Cedar Crest Allentown, Pennsylvania | Site Public Contact - (Morgan_M.Horton@lvhn.org) |
| Lehigh Valley Hospital-Hazleton Hazleton, Pennsylvania | Site Public Contact - (Morgan_M.Horton@lvhn.org) |
| Lewis Cancer and Research Pavilion at Saint Joseph's/Candler Savannah, Georgia | |
| Lewistown Hospital Lewistown, Pennsylvania | Site Public Contact - (cancerresearch@geisinger.edu) |
| Licking Memorial Hospital Newark, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Logan Health Medical Center Kalispell, Montana | Site Public Contact - (mccinfo@mtcancer.org) |
| Longmont United Hospital Longmont, Colorado | |
| Louisiana State University Health Science Center New Orleans, Louisiana | Site Public Contact - (emede1@lsuhsc.edu) |
| Lourdes Hospital Binghamton, New York | |
| Loyola Center for Health at Burr Ridge Burr Ridge, Illinois | |
| Loyola Medicine Homer Glen Homer Glen, Illinois | |
| Loyola University Medical Center Maywood, Illinois | |
| MU Health Care Goldschmidt Cancer Center Jefferson City, Missouri | |
| Macomb Hematology Oncology PC Warren, Michigan | |
| Margaret R Pardee Memorial Hospital Hendersonville, North Carolina | Site Public Contact - (pardeecancerresearch@unchealth.unc.edu) |
| Marietta Memorial Hospital Marietta, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Marion L Shepard Cancer Center - ECU Health Beaufort Hospital Washington, North Carolina | Site Public Contact - (research@ecuhealth.org) |
| Marjorie Weinberg Cancer Center at Loyola-Gottlieb Melrose Park, Illinois | |
| Marshfield Clinic - Wisconsin Rapids Center Wisconsin Rapids, Wisconsin | |
| Marshfield Clinic-Chippewa Center Chippewa Falls, Wisconsin | |
| Marshfield Clinic-Wausau Center Wausau, Wisconsin | |
| Marshfield Medical Center - Ladysmith Ladysmith, Wisconsin | |
| Marshfield Medical Center - Minocqua Minocqua, Wisconsin | |
| Marshfield Medical Center - Weston Weston, Wisconsin | |
| Marshfield Medical Center-EC Cancer Center Eau Claire, Wisconsin | |
| Marshfield Medical Center-Marshfield Marshfield, Wisconsin | |
| Marshfield Medical Center-Rice Lake Rice Lake, Wisconsin | |
| Marshfield Medical Center-River Region at Stevens Point Stevens Point, Wisconsin | |
| Mary Greeley Medical Center Ames, Iowa | |
| Mayo Clinic Hospital in Arizona Phoenix, Arizona | |
| Mayo Clinic in Florida Jacksonville, Florida | |
| Mayo Clinic in Rochester Rochester, Minnesota | |
| McFarland Clinic - Ames Ames, Iowa | |
| McFarland Clinic - Boone Boone, Iowa | |
| McFarland Clinic - Jefferson Jefferson, Iowa | |
| McFarland Clinic - Marshalltown Marshalltown, Iowa | |
| McFarland Clinic - Trinity Cancer Center Fort Dodge, Iowa | |
| Medical College of Wisconsin Milwaukee, Wisconsin | |
| Medical Oncology Hematology Consultants PA Newark, Delaware | Site Public Contact - (lbarone@christianacare.org) |
| Memorial Hospital Marysville, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Memorial Hospital of Carbondale Carbondale, Illinois | Site Public Contact - (clinical.research@sih.net) |
| Memorial Hospital of Laramie County Cheyenne, Wyoming | Site Public Contact - (protocols@AllianceNCTN.org) |
| Memorial Hospital of South Bend South Bend, Indiana | |
| Mercy Cancer Center Merced, California | |
| Mercy Cancer Center - Cape Girardeau Cape Girardeau, Missouri | |
| Mercy Cancer Center - Carmichael Carmichael, California | |
| Mercy Cancer Center - Elk Grove Elk Grove, California | |
| Mercy Cancer Center - Rocklin Rocklin, California | |
| Mercy Cancer Center - Sacramento Sacramento, California | |
| Mercy Cancer Center-West Lakes Clive, Iowa | |
| Mercy Clinic-Rolla-Cancer and Hematology Rolla, Missouri | |
| Mercy Health - Paducah Cancer Center Paducah, Kentucky | |
| Mercy Health - Perrysburg Hospital Perrysburg, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Mercy Health - Saint Anne Hospital Toledo, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Mercy Health - Saint Vincent Hospital Toledo, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Mercy Hospital Coon Rapids, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Mercy Hospital Fort Smith Fort Smith, Arkansas | |
| Mercy Hospital Joplin Joplin, Missouri | Site Public Contact - (esmeralda.carrillo@mercy.net) |
| Mercy Hospital Oklahoma City Oklahoma City, Oklahoma | |
| Mercy Hospital Pittsburg Pittsburg, Kansas | |
| Mercy Hospital Saint Louis St Louis, Missouri | |
| Mercy Hospital South St Louis, Missouri | Site Public Contact - (Danielle.Werle@mercy.net) |
| Mercy Hospital Springfield Springfield, Missouri | |
| Mercy Hospital Washington Washington, Missouri | |
| Mercy Infusion Center - Chippewa St Louis, Missouri | |
| Mercy Medical Center Springfield, Massachusetts | |
| Mercy Medical Center Springfield, Massachusetts | |
| Mercy Medical Center - Des Moines Des Moines, Iowa | |
| Mercy Medical Center-West Lakes West Des Moines, Iowa | |
| Mercy Oncology and Hematology - Clayton-Clarkson Ballwin, Missouri | |
| Mercy San Juan Medical Center Carmichael, California | |
| MercyOne Genesis Davenport Cancer Center Davenport, Iowa | |
| MercyOne Genesis Davenport Medical Center Davenport, Iowa | |
| MercyOne Genesis Silvis Cancer Center Silvis, Illinois | |
| Methodist Medical Center of Illinois Peoria, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Methodist West Hospital West Des Moines, Iowa | |
| Miami Valley Cancer Care and Infusion Greenville, Ohio | |
| Miami Valley Hospital Dayton, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Miami Valley Hospital North Dayton, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Miami Valley Hospital South Centerville, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Michigan Healthcare Professionals Pontiac Pontiac, Michigan | Site Public Contact - (Emily.Crofts@trinity-health.org) |
| Midlands Community Hospital Papillion, Nebraska | |
| Minneapolis VA Medical Center Minneapolis, Minnesota | |
| Minnesota Oncology - Burnsville Burnsville, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Minnesota Oncology Hematology PA-Maplewood Maplewood, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Minnesota Oncology Hematology PA-Woodbury Woodbury, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Mission Hope Medical Oncology - Arroyo Grande Arroyo Grande, California | |
| Mission Hope Medical Oncology - Santa Maria Santa Maria, California | |
| Missouri Baptist Medical Center St Louis, Missouri | |
| Missouri Baptist Sullivan Hospital Sullivan, Missouri | |
| Monticello Cancer Center Monticello, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Mount Carmel East Hospital Columbus, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Mount Carmel Grove City Hospital Grove City, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Mount Carmel Health Center West Columbus, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Mountain Blue Cancer Care Center - Swedish Englewood, Colorado | |
| MyMichigan Medical Center Alpena Alpena, Michigan | Site Public Contact - (CVResearch@mymichigan.org) |
| MyMichigan Medical Center Gladwin Gladwin, Michigan | Site Public Contact - (CVResearch@mymichigan.org) |
| MyMichigan Medical Center Gratiot Alma, Michigan | Site Public Contact - (CVResearch@mymichigan.org) |
| MyMichigan Medical Center Midland Midland, Michigan | Site Public Contact - (CVResearch@mymichigan.org) |
| MyMichigan Medical Center Mount Pleasant Mount Pleasant, Michigan | Site Public Contact - (CVResearch@mymichigan.org) |
| MyMichigan Medical Center Saginaw Saginaw, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| MyMichigan Medical Center Tawas Tawas City, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center New York, New York | |
| Nebraska Cancer Specialists/Oncology Hematology West PC Grand Island, Nebraska | |
| Nebraska Medicine-Bellevue Bellevue, Nebraska | Site Public Contact - (unmcrsa@unmc.edu) |
| Nebraska Medicine-Village Pointe Omaha, Nebraska | |
| New Ulm Medical Center New Ulm, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Newark Radiation Oncology Newark, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Newland Medical Associates-Clarkston Clarkston, Michigan | |
| Newland Medical Associates-Pontiac Pontiac, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| North Memorial Medical Health Center Robbinsdale, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| North Shore Medical Center Skokie, Illinois | Site Public Contact - (ctsucontact@westat.com) |
| North Star Lodge Cancer Center at Yakima Valley Memorial Hospital Yakima, Washington | Site Public Contact - (Memorial-ClinicalTrials@yvmh.org) |
| NorthShore University HealthSystem-Evanston Hospital Evanston, Illinois | |
| NorthShore University HealthSystem-Glenbrook Hospital Glenview, Illinois | |
| NorthShore University HealthSystem-Highland Park Hospital Highland Park, Illinois | |
| Northwest Medical Specialties PLLC Tacoma, Washington | |
| OSF Saint Anthony Medical Center Rockford, Illinois | |
| OSF Saint Anthony's Health Center Alton, Illinois | |
| Ohio State University Comprehensive Cancer Center Columbus, Ohio | Site Public Contact - (Jamesline@osumc.edu) |
| OhioHealth Mansfield Hospital Mansfield, Ohio | |
| OhioHealth Marion General Hospital Marion, Ohio | |
| Oncology Hematology Associates of Saginaw Valley PC Saginaw, Michigan | |
| Oncology Hematology Care Inc-Kenwood Cincinnati, Ohio | |
| Oncology Las Vegas - Henderson Henderson, Nevada | Site Public Contact - (research@sncrf.org) |
| Oncology Las Vegas - Tenaya Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| OptumCare Cancer Care at Charleston Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| OptumCare Cancer Care at Fort Apache Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| OptumCare Cancer Care at MountainView Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Orion Cancer Care Findlay, Ohio | |
| Our Lady of the Lake Medical Oncology Baton Rouge, Louisiana | Site Public Contact - (research@ololrmc.com) |
| Our Lady of the Lake Physician Group Baton Rouge, Louisiana | Site Public Contact - (research@ololrmc.com) |
| Overlake Medical Center Bellevue, Washington | |
| PCR Oncology Arroyo Grande, California | Site Public Contact - (research@sncrf.org) |
| Pacific Central Coast Health Center-San Luis Obispo San Luis Obispo, California | |
| Pacific Gynecology Specialists Seattle, Washington | |
| Park Nicollet Clinic - Saint Louis Park Saint Louis Park, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Parkland Health Center - Farmington Farmington, Missouri | |
| PeaceHealth Saint John Medical Center Longview, Washington | Site Public Contact - (kmakin-bond@peacehealth.org) |
| PeaceHealth Saint Joseph Medical Center Bellingham, Washington | Site Public Contact - (achapman1@peacehealth.org) |
| PeaceHealth Southwest Medical Center Vancouver, Washington | Site Public Contact - (kmakin-bond@peacehealth.org) |
| PeaceHealth United General Medical Center Sedro-Woolley, Washington | Site Public Contact - (achapman1@peacehealth.org) |
| Penrose-Saint Francis Healthcare Colorado Springs, Colorado | |
| Phelps Health Delbert Day Cancer Institute Rolla, Missouri | Site Public Contact - (research@phelpshealth.org) |
| Philadelphia Veterans Administration Medical Center Philadelphia, Pennsylvania | Site Public Contact - (ctsucontact@westat.com) |
| Pocono Medical Center East Stroudsburg, Pennsylvania | Site Public Contact - (Morgan_M.Horton@lvhn.org) |
| Portland VA Medical Center Portland, Oregon | |
| Pottstown Hospital Pottstown, Pennsylvania | |
| Premier Blood and Cancer Center Dayton, Ohio | |
| Presbyterian - Saint Lukes Medical Center - Health One Denver, Colorado | |
| Princeton Community Hospital Princeton, West Virginia | |
| Providence Alaska Medical Center Anchorage, Alaska | Site Public Contact - (AKPAMC.OncologyResearchSupport@providence.org) |
| Providence Cancer Institute Clackamas Clinic Clackamas, Oregon | |
| Providence Hood River Memorial Hospital Hood River, Oregon | Site Public Contact - (canrsrchstudies@provdience.org) |
| Providence Newberg Medical Center Newberg, Oregon | Site Public Contact - (CanRsrchStudies@providence.org) |
| Providence Portland Medical Center Portland, Oregon | Site Public Contact - (CanRsrchStudies@providence.org) |
| Providence Regional Cancer Partnership Everett, Washington | Site Public Contact - (marilyn.birchman@providence.org) |
| Providence Regional Cancer System-Aberdeen Aberdeen, Washington | Site Public Contact - (deidre.dillon@providence.org) |
| Providence Regional Cancer System-Centralia Centralia, Washington | Site Public Contact - (deidre.dillon@providence.org) |
| Providence Regional Cancer System-Lacey Lacey, Washington | Site Public Contact - (deidre.dillon@providence.org) |
| Providence Regional Cancer System-Shelton Shelton, Washington | |
| Providence Regional Cancer System-Yelm Yelm, Washington | |
| Providence Saint Joseph Medical Center/Disney Family Cancer Center Burbank, California | Site Public Contact - (Najee.Boucher@providence.org) |
| Providence Saint Mary Regional Cancer Center Walla Walla, Washington | Site Public Contact - (Cheryl.Dodd@providence.org) |
| Providence Saint Vincent Medical Center Portland, Oregon | Site Public Contact - (CanRsrchStudies@providence.org) |
| Providence Veterans Administration Hospital Providence, Rhode Island | |
| Providence Willamette Falls Medical Center Oregon City, Oregon | Site Public Contact - (CanRsrchStudies@providence.org) |
| Radiation Oncology Associates Reno, Nevada | |
| Radiation Oncology Centers of Nevada Central Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Radiation Oncology Centers of Nevada Southeast Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Redeemer Health Meadowbrook, Pennsylvania | |
| Regions Hospital Saint Paul, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Reid Health Richmond, Indiana | |
| Reiman Cancer Center-Ascension Wisconsin Health Center-Rawson Franklin, Wisconsin | Site Public Contact - (AWRI.Inquiry@Ascension.org) |
| Renown Regional Medical Center Reno, Nevada | Site Public Contact - (Renown-CRD@renown.org) |
| Rice Memorial Hospital Willmar, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Ridgeview Medical Center Waconia, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Riverside Methodist Hospital Columbus, Ohio | |
| Rocky Mountain Cancer Centers - Centennial Centennial, Colorado | |
| Rocky Mountain Cancer Centers - Swedish Englewood, Colorado | |
| Rocky Mountain Cancer Centers-Aurora Aurora, Colorado | |
| Rocky Mountain Cancer Centers-Boulder Boulder, Colorado | |
| Rocky Mountain Cancer Centers-Lakewood Lakewood, Colorado | |
| Rocky Mountain Cancer Centers-Littleton Littleton, Colorado | |
| Rocky Mountain Cancer Centers-Longmont Longmont, Colorado | |
| Rocky Mountain Cancer Centers-Midtown Denver, Colorado | |
| Rocky Mountain Cancer Centers-Penrose Colorado Springs, Colorado | |
| Rocky Mountain Cancer Centers-Rose Denver, Colorado | |
| Rocky Mountain Cancer Centers-Sky Ridge Lone Tree, Colorado | |
| Rocky Mountain Cancer Centers-Thornton Thornton, Colorado | |
| Roger Williams Medical Center Providence, Rhode Island | Site Public Contact - (fdallesandro@chartercare.org) |
| Roswell Park Cancer Institute Buffalo, New York | Site Public Contact - (askroswell@roswellpark.org) |
| Rush-Copley Healthcare Center Yorkville, Illinois | Site Public Contact - (Cancer.Research@rushcopley.com) |
| Rush-Copley Medical Center Aurora, Illinois | Site Public Contact - (RCMC_Cancer_Research@rush.edu) |
| SIH Cancer Institute Carterville, Illinois | Site Public Contact - (clinical.research@sih.net) |
| SSM Health Good Samaritan Mount Vernon, Illinois | Site Public Contact - (gayla.hall@ssmhealth.com) |
| SUNY Upstate Medical Center-Community Campus Syracuse, New York | |
| Saint Alphonsus Cancer Care Center-Baker City Baker City, Oregon | Site Public Contact - (mccinfo@mtcancer.org) |
| Saint Alphonsus Cancer Care Center-Boise Boise, Idaho | Site Public Contact - (stephanie.couch@stjoeshealth.org) |
| Saint Alphonsus Cancer Care Center-Caldwell Caldwell, Idaho | Site Public Contact - (stephanie.couch@stjoeshealth.org) |
| Saint Alphonsus Cancer Care Center-Nampa Nampa, Idaho | Site Public Contact - (mccinfo@mtcancer.org) |
| Saint Alphonsus Cancer Care Center-Ontario Ontario, Oregon | Site Public Contact - (mccinfo@mtcancer.org) |
| Saint Ann's Hospital Westerville, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Saint Anthony North Hospital Westminster, Colorado | |
| Saint Charles Health System Bend, Oregon | Site Public Contact - (nosall@stcharleshealthcare.org) |
| Saint Charles Health System-Redmond Redmond, Oregon | |
| Saint Clare Hospital Lakewood, Washington | |
| Saint Elizabeth Boardman Hospital Boardman, Ohio | |
| Saint Elizabeth Hospital Enumclaw, Washington | |
| Saint Elizabeth Regional Medical Center Lincoln, Nebraska | |
| Saint Elizabeth Youngstown Hospital Youngstown, Ohio | |
| Saint Francis Cancer Center Greenville, South Carolina | |
| Saint Francis Cancer Center Greenville, South Carolina | Site Public Contact - (Heather_Rich@bshsi.org) |
| Saint Francis Hospital Greenville, South Carolina | Site Public Contact - (Heather_Rich@bshsi.org) |
| Saint Francis Hospital Greenville, South Carolina | |
| Saint Francis Medical Center Cape Girardeau, Missouri | Site Public Contact - (sfmc@sfmc.net) |
| Saint Francis Regional Medical Center Shakopee, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Saint Helena Hospital St. Helena, California | |
| Saint John's Hospital - Healtheast Maplewood, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Saint Joseph Medical Center Hematology and Oncology - Silverdale Silverdale, Washington | |
| Saint Joseph Radiation Oncology Resource Center Lexington, Kentucky | |
| Saint Joseph Regional Cancer Center Bryan, Texas | |
| Saint Joseph Warren Hospital Warren, Ohio | |
| Saint Joseph's Medical Center Stockton, California | |
| Saint Joseph's/Candler - Bluffton Campus Bluffton, South Carolina | |
| Saint Luke's Cancer Institute - Boise Boise, Idaho | Site Public Contact - (eslinget@slhs.org) |
| Saint Luke's Cancer Institute - Fruitland Fruitland, Idaho | Site Public Contact - (eslinget@slhs.org) |
| Saint Luke's Cancer Institute - Meridian Meridian, Idaho | Site Public Contact - (eslinget@slhs.org) |
| Saint Luke's Cancer Institute - Nampa Nampa, Idaho | Site Public Contact - (eslinget@slhs.org) |
| Saint Luke's Cancer Institute - Twin Falls Twin Falls, Idaho | Site Public Contact - (eslinget@slhs.org) |
| Saint Mary Corwin Medical Center Pueblo, Colorado | |
| Saint Mary's Oncology/Hematology Associates of Marlette Marlette, Michigan | |
| Saint Mary's Oncology/Hematology Associates of West Branch West Branch, Michigan | |
| Saint Mary's Regional Medical Center Reno, Nevada | Site Public Contact - (research@sncrf.org) |
| Saint Patrick Hospital - Community Hospital Missoula, Montana | Site Public Contact - (amy.hanneman@providence.org) |
| Saint Peter's Community Hospital Helena, Montana | |
| Saint Rita's Medical Center Lima, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Sainte Genevieve County Memorial Hospital Sainte Genevieve, Missouri | |
| Saints Mary and Elizabeth Hospital Louisville, Kentucky | |
| Sanford Bismarck Medical Center Bismarck, North Dakota | Site Public Contact - (OncologyClinicalTrialsFargo@sanfordhealth.org) |
| Sanford Broadway Medical Center Fargo, North Dakota | Site Public Contact - (OncologyClinicalTrialsFargo@sanfordhealth.org) |
| Sanford Cancer Center Oncology Clinic Sioux Falls, South Dakota | Site Public Contact - (OncologyClinicTrialsSF@sanfordhealth.org) |
| Sanford Cancer Center Worthington Worthington, Minnesota | |
| Sanford Joe Lueken Cancer Center Bemidji, Minnesota | Site Public Contact - (OncologyClinicalTrialsFargo@sanfordhealth.org) |
| Sanford Medical Center Fargo Fargo, North Dakota | |
| Sanford Roger Maris Cancer Center Fargo, North Dakota | Site Public Contact - (OncologyClinicalTrialsFargo@sanfordhealth.org) |
| Sanford South University Medical Center Fargo, North Dakota | |
| Sanford Thief River Falls Medical Center Thief River Falls, Minnesota | |
| Sanford USD Medical Center - Sioux Falls Sioux Falls, South Dakota | Site Public Contact - (OncologyClinicalTrialsSF@SanfordHealth.org) |
| Sechler Family Cancer Center Lebanon, Pennsylvania | Site Public Contact - (doxenberg@wellspan.org) |
| Singing River Hospital Pascagoula, Mississippi | |
| Siteman Cancer Center at Christian Hospital St Louis, Missouri | Site Public Contact - (info@siteman.wustl.edu) |
| Siteman Cancer Center at Saint Peters Hospital City of Saint Peters, Missouri | Site Public Contact - (info@siteman.wustl.edu) |
| Siteman Cancer Center at West County Hospital Creve Coeur, Missouri | Site Public Contact - (info@siteman.wustl.edu) |
| Siteman Cancer Center-South County St Louis, Missouri | Site Public Contact - (info@siteman.wustl.edu) |
| Skagit Regional Health Cancer Care Center Mount Vernon, Washington | Site Public Contact - (rcccclinicalresearch@skagitvalleyhospital.org) |
| South Carolina Cancer Specialists PC Hilton Head Island, South Carolina | |
| Southern Illinois University School of Medicine Springfield, Illinois | |
| Southern Ohio Medical Center Portsmouth, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Southpointe-Sanford Medical Center Fargo Fargo, North Dakota | |
| Southwest Illinois Health Services LLP Swansea, Illinois | |
| Springfield Clinic Springfield, Illinois | |
| Springfield Memorial Hospital Springfield, Illinois | Site Public Contact - (pallante.beth@mhsil.com) |
| Springfield Regional Cancer Center Springfield, Ohio | |
| Springfield Regional Medical Center Springfield, Ohio | |
| State University of New York Upstate Medical University Syracuse, New York | |
| Strecker Cancer Center-Belpre Belpre, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Summerlin Hospital Medical Center Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Sunrise Hospital and Medical Center Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Swedish Cancer Institute-Edmonds Edmonds, Washington | Site Public Contact - (PCRC-NCORP@Swedish.org) |
| Swedish Cancer Institute-Issaquah Issaquah, Washington | Site Public Contact - (PCRC-NCORP@Swedish.org) |
| Swedish Covenant Hospital Chicago, Illinois | |
| Swedish Medical Center-Ballard Campus Seattle, Washington | Site Public Contact - (PCRC-NCORP@Swedish.org) |
| Swedish Medical Center-Cherry Hill Seattle, Washington | Site Public Contact - (PCRC-NCORP@Swedish.org) |
| Swedish Medical Center-First Hill Seattle, Washington | Site Public Contact - (PCRC-NCORP@Swedish.org) |
| The Carle Foundation Hospital Urbana, Illinois | Site Public Contact - (Research@carle.com) |
| The Don and Sybil Harrington Cancer Center Amarillo, Texas | Site Public Contact - (Gina.Cravey@bsahs.org) |
| The Mark H Zangmeister Center Columbus, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| The Melanoma and Skin Cancer Institute Englewood, Colorado | |
| The Women's Imaging Center Denver, Colorado | |
| TidalHealth Nanticoke / Allen Cancer Center Seaford, Delaware | |
| TriHealth Cancer Institute-Anderson Cincinnati, Ohio | |
| TriHealth Cancer Institute-Westside Cincinnati, Ohio | |
| Trinity Health Grand Rapids Hospital Grand Rapids, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
| Trinity Health IHA Medical Group - Primary Care - Clarkston Clarkston, Michigan | Site Public Contact - (Emily.Crofts@Trinity-Health.org) |
| Trinity Health IHA Medical Group Hematology Oncology - Brighton Brighton, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Trinity Health IHA Medical Group Hematology Oncology - Canton Canton, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital Chelsea, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus Ypsilanti, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Trinity Health Medical Center - Brighton Brighton, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Trinity Health Medical Center - Canton Canton, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Trinity Health Muskegon Hospital Muskegon, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
| Trinity Health Saint Joseph Mercy Hospital Ann Arbor Ann Arbor, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Trinity Health Saint Joseph Mercy Oakland Hospital Pontiac, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Trinity Health Saint Mary Mercy Livonia Hospital Livonia, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| UI Health Care Mission Cancer and Blood - Des Moines Clinic Des Moines, Iowa | |
| UI Health Care Mission Cancer and Blood - Laurel Clinic Des Moines, Iowa | |
| UI Health Care Mission Cancer and Blood - West Des Moines Clinic Clive, Iowa | |
| UI Healthcare Mission Cancer and Blood - Fort Dodge Fort Dodge, Iowa | |
| UM Baltimore Washington Medical Center/Tate Cancer Center Glen Burnie, Maryland | |
| UM Saint Joseph Medical Center Towson, Maryland | Site Public Contact - (Jeanmarie.downing@umm.edu) |
| United Hospital Saint Paul, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| United Hospital Center Bridgeport, West Virginia | Site Public Contact - (cancertrialsinfo@hsc.wvu.edu) |
| Unity Hospital Fridley, Minnesota | |
| University Cancer Center Las Vegas, Nevada | |
| University Medical Center New Orleans New Orleans, Louisiana | Site Public Contact - (emede1@lsuhsc.edu) |
| University Medical Center of Southern Nevada Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| University of Cincinnati Cancer Center-UC Medical Center Cincinnati, Ohio | |
| University of Cincinnati Cancer Center-West Chester West Chester, Ohio | |
| University of Maryland/Greenebaum Cancer Center Baltimore, Maryland | |
| University of Michigan Health - Sparrow Lansing Lansing, Michigan | Site Public Contact - (harsha.trivedi@umhsparrow.org) |
| University of Minnesota/Masonic Cancer Center Minneapolis, Minnesota | |
| University of Nebraska Medical Center Omaha, Nebraska | Site Public Contact - (unmcrsa@unmc.edu) |
| University of New Mexico Cancer Center Albuquerque, New Mexico | |
| University of Washington Medical Center - Montlake Seattle, Washington | |
| UofL Health Medical Center Northeast Louisville, Kentucky | |
| Upper Valley Medical Center Troy, Ohio | |
| Upstate Cancer Center at Oswego Oswego, New York | Site Public Contact - (McDowelE@upstate.edu) |
| Upstate Cancer Center at Verona Verona, New York | Site Public Contact - (McDowelE@upstate.edu) |
| Urology Specialists of Nevada - Central Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Urology Specialists of Nevada - Green Valley Henderson, Nevada | Site Public Contact - (research@sncrf.org) |
| Urology Specialists of Nevada - Northwest Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Urology Specialists of Nevada - Southwest Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| VCU Massey Comprehensive Cancer Center Richmond, Virginia | Site Public Contact - (CTOclinops@vcu.edu) |
| Valley Medical Center Renton, Washington | Site Public Contact - (research@valleymed.org) |
| Valley Radiation Oncology Peru, Illinois | |
| Veterans Affairs Connecticut Healthcare System-West Haven Campus West Haven, Connecticut | |
| Veterans Affairs Loma Linda Healthcare System Loma Linda, California | |
| Vince Lombardi Cancer Clinic - Oshkosh Oshkosh, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Vince Lombardi Cancer Clinic-Sheboygan Sheboygan, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Vince Lombardi Cancer Clinic-Two Rivers Two Rivers, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| WVUH-Berkely Medical Center Martinsburg, West Virginia | Site Public Contact - (cancertrialsinfo@hsc.wvu.edu) |
| Walter Knox Memorial Hospital Emmett, Idaho | |
| Washington Health Fremont, California | |
| Washington University School of Medicine St Louis, Missouri | Site Public Contact - (info@siteman.wustl.edu) |
| Wayne Hospital Greenville, Ohio | |
| Welch Cancer Center Sheridan, Wyoming | |
| WellSpan Health-York Cancer Center York, Pennsylvania | |
| WellSpan Health-York Hospital York, Pennsylvania | |
| WellSpan Medical Oncology and Hematology Hanover, Pennsylvania | |
| WellSpan Medical Oncology and Hematology Hanover, Pennsylvania | |
| West Jefferson Medical Center Marrero, Louisiana | Site Public Contact - (emede1@lsuhsc.edu) |
| West Suburban Medical Center River Forest, Illinois | |
| West Virginia University Healthcare Morgantown, West Virginia | Site Public Contact - (cancertrialsinfo@hsc.wvu.edu) |
| Western Illinois Cancer Treatment Center Galesburg, Illinois | |
| Wheeling Hospital/Schiffler Cancer Center Wheeling, West Virginia | |
| Woodland Memorial Hospital Woodland, California | |
| Zuckerberg San Francisco General Hospital San Francisco, California | Site Public Contact - (Paul.Couey@ucsf.edu) |
Neuroscience-informed Treatment to Remotely Target Reward Mechanisms in Post-acute Anorexia Nervosa
Kira Venables - venableskg@vcu.edu
NCT05799872
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Inclusion Criteria:
• Age \> or = 18 years old
• Ability to read and speak in English
• DSM-5 diagnosis of AN or atypical AN at admission to higher-level care
• In higher-level care discharging to outpatient care or discharged to outpatient care within the past 3 months
• Current BMI \> or = 18.5 kg/m2 (or will be by time of discharge)
• BMI increase of \> or = 0.5 kg/m2 while in higher-level care
• Ability to designate and sign a release of information for a primary physical or mental health provider for study duration
• Willingness to participate in weekly assessments (e.g., weight monitoring) and audio or video recording of study therapy sessions for study duration
• Access to a smartphone and/or computer permitting engagement in remote therapy and assessment.
Exclusion Criteria:
• Medical instability for outpatient care;
• Pregnancy
• Lifetime DSM-5 primary psychotic or bipolar-I disorder
• Current DSM-5 substance use disorder
• Enrollment in outpatient therapy with highly overlapping content to PAT-AN
BEHAVIORAL: Positive Affect Treatment for Anorexia Nervosa (PAT-AN):, BEHAVIORAL: Psychoeducational and Behavioral Therapy (PBT)
Anorexia Nervosa
I'm interested
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Show 1 location
Study Locations
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia |
Comprehensive Tobacco Cessation for Cancer Patients and Survivors
Antonice Wall - walla2@vcu.edu
NCT05805722
Show full eligibility criteria
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Inclusion Criteria:
* Provision of signed and dated informed consent form
* Stated willingness to comply with study procedures and availability for the duration of the study
* Have a documented history of cancer of any type, whether active or in remission
* Identify as a current or recently-quit tobacco user
Exclusion Criteria:
* Not a VCUHealth patient
* Non English-speaking BEHAVIORAL: Behavioral counseling for tobacco cessation
Tobacco Use Cessation, Cancer
I'm interested
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See this study on ClinicalTrials.gov
Show 1 location
Study Locations
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Massey CPC Team - (masseycpc@vcu.edu) |
A Phase 1/2 Study of Bleximenib in Participants With Acute Leukemia (cAMeLot-1) (cAMeLot-1)
Study Contact - Participate-In-This-Study1@its.jnj.com
NCT04811560
Show full eligibility criteria
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Inclusion Criteria:
Phase 1:
* Age 2 years to less than (\<) 18 years of age (pediatric cohort only), all other cohorts 18 years and above
* Relapsed or refractory (R/R) acute leukemia and has exhausted, or is ineligible for, available therapeutic options
* Acute leukemia harboring histone-lysine N-methyltransferase 2A (KMT2A), nucleophosmin 1 gene (NPM1) or nucleoporin 98 gene or nucleoporin 214 gene (NUP98 or NUP214) alterations
Phase: 2
* Participants greater than 18 years are eligible
* Must have had an initial diagnosis of acute myeloid leukemia (AML) per the WHO 2022 classification criteria and have relapsed/refractory disease
* AML harboring KMT2A-r (gene rearrangement/translocation) or NPM1 mutations only
For Both Phase 1 and 2:
* Pretreatment clinical laboratory values meeting the following criteria: (a) Hematology: white blood cell (WBC) count \<= 20\*10\^9/liter (L) and (b) renal function; For adult participants, estimated or measured glomerular filtration rate \>= 30 milliliter per minute (mL/min) per four variable MDRD equation. For pediatric participants an estimated or measured glomerular filtration rate \>=40 mL/min per the CKiD (Chronic Kidney Disease in Children) Schwartz formula
* Eastern Cooperative Oncology Group (ECOG) performance status grade of 0, 1 or 2. Pediatric participants only: Performance status \>=70 by Lansky scale (for participants \< 16 years of age) or \>=70 Karnofsky scale (for participants \>=16 years of age)
* A female of childbearing potential must have a negative highly sensitive serum beta-human chorionic gonadotropin at screening and within 48 hours prior to the first dose of study treatment
* Participant must agree to all protocol required contraception requirements and avoid sperm or egg donations or freezing for future reproductive use while on study and for 90 days (males) or 6 months (females) after the last dose of study treatment
Exclusion Criteria:
* Acute promyelocytic leukemia, diagnosis of Down syndrome associated leukemia or juvenile myelomonocytic leukemia according to World Health Organization (WHO) 2016 criteria
* Active central nervous system (CNS) disease
* Prior solid organ transplantation
* QTc according to Fridericia's formula (QTcF) for males \>= 450 millisecond (msec) or for females \>= 470 msec. Participants with a family history of Long QT syndrome are excluded
* Exclusion criteria related to stem cell transplant: a. Received prior treatment with allogenic bone marrow or stem cell transplant \<=3 months before the first dose of study treatment ; b. Has evidence of graft versus host disease; c. Received donor lymphocyte infusion \<=1 month before the first dose of study treatment; d. Requires immunosuppressant therapy (exception: daily doses \<=10 milligrams (mg) prednisone or equivalent are allowed for adrenal replacement)
* Prior cancer immunotherapy within 4 weeks prior to enrollment or blinatumomab within 2 weeks prior to enrollment. Additional prior cancer therapies must not be given within 4 weeks prior to enrollment or 5 half-lives of the agent (whichever is shorter) DRUG: Bleximenib
Acute Leukemia
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Show 102 locations
Study Locations
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| Location | Contacts |
|---|---|
| Asan Medical Center Seoul, | |
| Baylor University Medical Center Dallas, Texas | |
| CHRU Nancy Brabois Vandœuvre-lès-Nancy, | |
| CHRU de Nancy - Hôpitaux de Brabois Vandœuvre-lès-Nancy, | |
| CHU Bretonneau Tours, | |
| CHU Lyon Sud Pierre-Bénite, | |
| CHU de Nantes hotel Dieu Nantes, | |
| Carmel Medical Center Haifa, | |
| Centre Hospitalier Universitaire (CHU) de Bordeaux Hopital HautLeveque Centre Francois Magendie Pessac, | |
| China Medical University Hospital Taichung, | |
| City of Hope Duarte, California | |
| Clinica Univ. de Navarra Pamplona, | |
| Dana Farber Cancer Institute Boston, Massachusetts | |
| First Affiliated Hospital Medical School of Zhejiang University Hangzhou, | |
| Fox Chase Cancer Center Philadelphia, Pennsylvania | |
| Fukushima Medical University Hospital Fukushima, | |
| Fundacao Antonio Prudente A C Camargo Cancer Center São Paulo, | |
| Fundação Faculdade de Medicina - Instituto do Cancer do Estado de São Paulo São Paulo, | |
| Ghent University Hospital Ghent, | |
| Gold Coast University Hospital Southport, | |
| Gunmaken Saiseikai Maebashi Hospital Maebashi, | |
| Gustave Roussy Villejuif, Val-de-marne | |
| Guys and St Thomas NHS Foundation Trust London, | |
| Hadassah University Hospita Ein Kerem Jerusalem, | |
| Henan Cancer Hospital Zhengzhou, Henan | |
| Hokkaido University Hospital Hokkaido, Sapporo, | |
| Hopital Jean Minjoz Besançon, | |
| Hopital Maisonneuve Rosemont Montreal, Quebec | |
| Hopital Saint Louis Paris, | |
| Hopital trousseau- APHP Paris, | |
| Hopitaux Universitaires de Strasbourg - Hopital de Hautepierre Strasbourg, | |
| Hosp Clinic de Barcelona Barcelona, | |
| Hosp Clinico Univ de Salamanca Salamanca, | |
| Hosp Univ Fund Jimenez Diaz Madrid, | |
| Hosp Univ Vall D Hebron Barcelona, | |
| Hosp. Clinico Univ. de Valencia Valencia, | |
| Hosp. Gral. Univ. Gregorio Marañon Madrid, | |
| Hosp. Virgen Del Rocio Seville, | |
| Hospital Infantil Universitario Nino Jesus Madrid, | |
| Houston Methodist Hospital Houston, Texas | |
| IDOR - Regional Brasilia Brasília, | |
| IDOR - Regional Sao Paulo São Paulo, | |
| Institut Paoli Calmettes Marseille, | |
| Institut Universitaire du Cancer Toulouse Oncopole Toulouse, | |
| Institute of Hematology and Blood Diseases Hospital Tianjin, | |
| Kanazawa University Hospital Ishikawa, Kanazawa, | |
| Karmanos Cancer Institute Detroit, Michigan | |
| Kobe City Medical Center General Hospital Kobe, | |
| Kyushu University Hospital Fukuoka, Fukuoka, | |
| Leeds Teaching Hospitals NHS Trust Leeds, | |
| Liga Norte Riograndense Contra O Cancer Natal, Rio Grande do Norte | |
| MD Anderson Houston, Texas | |
| Maine Health Providence, Rhode Island | |
| Massachusetts General Hospital Boston, Massachusetts | |
| Medical College of WI at Froedtert Milwaukee, Wisconsin | |
| Ministerio da Saude Instituto Nacional do Cancer Rio de Janeiro, | |
| Monash Medical Centre Clayton, Victoria | |
| Montefiore Medical Center The Bronx, New York | |
| NTT Medical Center Tokyo Tokyo, | |
| NYU Langone Medical Center New York, New York | |
| Nagoya University Hospital Aichi, Nagoya, | |
| Nanfang Hospital of Southern Medical Hospital Guangzhou, | |
| National Cancer Center Hospital East Kashiwa, Chiba | |
| National Cheng Kung University Hospital Tainan, | |
| National Taiwan University Hospital Taipei, | |
| Norton Cancer Institute Louisville, Kentucky | |
| Oregon Health and Science University Portland, Oregon | |
| Oxford University Hospitals NHS Trust Oxfordshire, | |
| Peking University First Hospital Beijing, | |
| Princess Margaret Cancer Centre University Health Network Toronto, Ontario | |
| Qilu Hospital of Shandong University Jinan, Shandong | |
| Roswell Park Comprehensive Cancer Center Buffalo, New York | |
| Royal Perth Hospital Perth, Western Australia | |
| START Midwest Grand Rapids, Michigan | |
| Samsung Medical Center Seoul, | |
| San Antonio Methodist TX Transplant Physicians Group San Antonio, Texas | |
| Seoul National University Hospital Seoul, | |
| Sheba Medical Center Ramat Gan, | |
| St Francis Hospital & Health Centers Indiana Blood and Marrow Transplantation Indianapolis, Indiana | |
| Swedish Cancer Institute Seattle, Washington | |
| Tel Aviv Sourasky Medical Center Tel Aviv, | |
| The Christie NHS Foundation Trust Manchester, Lancashire | |
| The Clatterbridge Cancer Centre Liverpool, | |
| The First Affiliated Hospital of NanChang University Nanchang, | |
| The First Affiliated Hospital of Wenzhou Medical University Wenzhou, | |
| UCSF Benioff Children's Hospital San Francisco, California | |
| Union Hospital Tongji Medical College of Huazhong University of Science and Technology Wuhan, | |
| University College London Hospitals London, | |
| University Hospital of Wales Cardiff, | |
| University Hospitals Plymouth NHS Trust Plymouth, | |
| University of California Irvine Medical Center Orange, California | |
| University of California San Francisco San Francisco, California | |
| University of Chicago Chicago, Illinois | |
| University of Fukui Hospital Yoshida, | |
| University of New Mexico Albuquerque, New Mexico | |
| University of Tennessee Medical Center Knoxville, Tennessee | |
| Vancouver Coastal Health Vancouver, British Columbia | |
| Virginia Commonwealth University Richmond, Virginia | |
| West China Hospital Si Chuan University Chengdu, | |
| Yamagata University Hospital Yamagata, Yamagata | |
| Zhongda Hospital Southeast University Nanjing, | |
| the First Hospital of Jilin University Changchun, |
Enhancing Oral Cancer Awareness
Tamas Gal, Ph.D - Tamas.Gal@vcuhealth.org
NCT06682494
Show full eligibility criteria
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Inclusion Criteria:
* Identify as African American as defined by the US Census
* Participants must be able to read, speak, and write in English
Exclusion Criteria:
* Individuals who cannot physically or mentally participate in the research project will be excluded
* Adults unable to consent
* Individuals who are not yet adults (infants, children, teenagers)
* Prisoners BEHAVIORAL: Traditional Education, BEHAVIORAL: AI-powered Chatbox
Oral Cancer, Chatbot, Patient Education, Prevention, Oral Cancer , Oral Squamous Cell Carcinoma, Oral Cavity Cancer, Oropharyngeal Cancers
AI-powered Chatbox, Oral cancer prevention, Socio-economic barriers
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Study Locations
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Tamas Gal, Ph.D - (Tamas.Gal@vcuhealth.org) |
Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003) (OMAHA-003)
Toll Free Number - Trialsites@msd.com
NCT06136624
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Inclusion Criteria:
* Has histologically- or cytologically-confirmed adenocarcinoma of the prostate without small cell histology.
* Has prostate cancer progression while on androgen deprivation therapy (or post bilateral orchiectomy) within 6 months before Screening
* Has current evidence of distant metastatic disease (M1 disease) documented by either bone lesions on bone scan and/or soft tissue disease by computed tomography/magnetic resonance imaging (CT/MRI).
* Has disease that progressed during or after treatment with 1 novel hormonal agent (NHA)
* Has received 1 but no more than 2 taxane-based chemotherapy regimens for metastatic castration-resistant prostate cancer (mCRPC) and has had progressive disease (PD) during or after treatment
* Has ongoing androgen deprivation with serum testosterone \<50 ng/dL (\<1.7 nM)
* Has provided tumor tissue from a fresh core or excisional biopsy from soft tissue not previously irradiated
* Has an Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1 assessed within 7 days of randomization
* Has had prior treatment with PARPi or were deemed ineligible to receive treatment by the investigator or have refused PARPi treatment
* Has received prior 177Lu-PSMA-617 or were deemed ineligible to receive 177Lu-PSMA-617 treatment by the investigator or refused 177Lu-PSMA-617 treatment
* Participants who have not received cabazitaxel can be enrolled if they are ineligible for cabazitaxel treatment as determined by the investigator or have refused treatment
* If participant received first generation anti-androgen therapy before screening, the participant has evidence of disease progression \>4 weeks since the last flutamide treatment and \>6 weeks since the last bicalutamide or nilutamide treatment
* Participants receiving bone resorptive therapy (including, but not limited to, bisphosphonate or denosumab) must have been on stable doses for ≥ 4 weeks before the date of randomization
* Participants with human immunodeficiency virus (HIV) infection must have well controlled HIV on antiretroviral therapy (ART)
* Participants who are hepatitis B surface antigen (HBsAg) positive are eligible if they have received hepatitis B virus (HBV) antiviral therapy for at least 4 weeks and have undetectable HBV viral load before randomization
* Participants with history of hepatitis C virus (HCV) infection are eligible if HCV viral load is undetectable at Screening.
* Participants who can produce sperm must agree to the following during the study treatment period and for at least 7 days after the last dose of opevesostat, for at least 30 days after the last dose of abiraterone acetate, and for at least 3 months after the last dose of enzalutamide: EITHER be abstinent OR must agree to use male condom
Exclusion Criteria:
* Has a gastrointestinal disorder that might affect absorption
* Has a history of pituitary dysfunction
* Has poorly controlled diabetes mellitus
* Has clinically significant abnormal serum potassium or sodium level
* Has a history of active or unstable cardio/cerebro-vascular disease, including thromboembolic events
* Has a history of seizure within 6 months of providing documented informed consent or any condition that may predispose to seizures within 12 months before the date of randomization
* Has a history of clinically significant ventricular arrhythmias
* Has received an anticancer monoclonal antibody (mAb) within 4 weeks before the date of randomization, or has not recovered from adverse events (AEs) due to mAbs administered more than 4 weeks before the date of randomization
* Has undergone major surgery, including local prostate intervention (except prostate biopsy), within 28 days before the date of randomization, and has not recovered from the toxicities and/or complications
* Participants who have not adequately recovered from major surgery or have ongoing surgical complications
* Has used herbal or medicinal products that may have hormonal anti-prostate cancer activity and/or are known to decrease prostate-specific Antigen (PSA) (eg, saw palmetto, megesterol acetate, citrus pectin polysaccharide) within 4 weeks before the date of randomization
* Has received radium-223 or Lutetium-177 within 4 weeks before the date of randomization, or has not recovered to Grade ≤1 or baseline from AEs due to radium-223 or Lutetium-177 administered more than 4 weeks before the date of randomization
* Has received treatment with 5-αreductase inhibitors (eg, finasteride or dutasteride), estrogens, or cyproterone within 4 weeks before the date of randomization
* Has received colony-stimulating factors within 28 days before the date of randomization
* Has received a whole blood transfusion in the last 120 days before the date of randomization. Packed red blood cells and platelet transfusions are acceptable if not given within 28 days of the date of randomization
* Has received prior targeted small molecule therapy or NHA treatment within 4 weeks before the first dose of study intervention as follows: enzalutamide or apalutamide within 3 weeks or abiraterone acetate + prednisone or darolutamide within 2 weeks
* Has a "superscan" bone scan
* Has a diagnosis of immunodeficiency or is receiving chronic systemic steroid therapy or any other form of immunosuppressive therapy within 7 days prior the first dose of study medication
* Has a known additional malignancy that is progressing or has required active treatment within the past 3 years
* Has known active central nervous system (CNS) metastases and/or carcinomatous meningitis
* Has an active autoimmune disease that has required systemic treatment in past 2 years
* Has an active infection requiring systemic therapy
* Has concurrent active HBV or known active HCV infection
* Has a history of long QTc syndrome
* Has any of the following at Screening Visit: hypotension (systolic BP \<110 mm Hg) or uncontrolled hypertension (systolic BP ≥160 mm Hg or diastolic BP ≥90 mm Hg, in 2 out of 3 recordings with optimized antihypertensive therapy)
* Is unable to swallow capsules/tablets
* Is currently being treated with cytochrome 450-inducing antiepileptic drugs for seizures
* Participants on an unstable dose of thyroid hormone therapy within 6 months before the start of the study intervention
* Received prior systemic anticancer therapy including investigational agents within 4 weeks before the first dose of study intervention
* Received prior radiotherapy within 2 weeks of start of study intervention, or radiation-related toxicities, requiring corticosteroids
* Received a live or live-attenuated vaccine within 30 days before the first dose of study intervention
* Systemic use of the following medications within 2 weeks before the first dose of study intervention: strong CYP3A4 inducers (eg, avasimibe, carbamazepine, lumacaftor, phenobarbital, rifampicin, rifapentine, or St John's Wort); P-gp inhibitors (eg, erythromycin, clarithromycin, rifampicin, ketoconazole, itraconazole, posaconazole, artesunate-pyronaridine, ritonavir, indinavir, nelfinavir, atazanavir, glecaprevir-pibrentasvir, simeprevir, ledipasvir-sofosbuvir, verapamil, diltiazem, dronedarone, propafenone, quinidine, cyclosporine, valspodar, or milk thistle \[Silybum marianum\])
* Use of aldosterone antagonist (eg, spironolactone, eplerenone) and phenytoin within 4 weeks before the start of the study intervention DRUG: Opevesostat, DRUG: Abiraterone acetate, DRUG: Enzalutamide, DRUG: Hydrocortisone, DRUG: Fludrocortisone acetate, DRUG: Prednisone, DRUG: Dexamethasone
Prostate Cancer Metastatic
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Show 288 locations
Study Locations
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| Location | Contacts |
|---|---|
| A. C. Camargo Cancer Center ( Site 0310) São Paulo, São Paulo | |
| AHN Allegheny General Hospital ( Site 0001) Pittsburgh, Pennsylvania | |
| Ad-Vance Medical Research-Research ( Site 1353) Ponce, | |
| Addenbrooke's Hospital ( Site 1605) Cambridge, Cambridgeshire | |
| Affiliated hospital of Jiangnan university ( Site 0434) Wuxi, Jiangsu | |
| Akademiska sjukhuset-Blod- och tumörsjukdomar ( Site 1477) Uppsala, Uppsala County | |
| Akershus Universitetssykehus-Onkologisk avdeling ( Site 1227) Lørenskog, Akershus | |
| Akita University Hospital ( Site 0904) Akita, | |
| Aliada-Oncologìa ( Site 1257) Lima, | |
| Amsterdam UMC, locatie VUmc ( Site 1156) Amsterdam, North Holland | |
| Ankara Bilkent Şehir Hastanesi-Medical Oncology ( Site 1552) Ankara, | |
| Anschutz Cancer Pavilion ( Site 0046) Aurora, Colorado | |
| Asahikawa Medical University Hospital ( Site 0901) Asahikawa, Hokkaido | |
| Asan Medical Center-Oncology ( Site 1402) Songpagu, Seoul | |
| Asociación de Beneficencia Hospital Sirio Libanés ( Site 0205) Buenos Aires, Buenos Aires F.D. | |
| Atlantic Health System Morristown Medical Center ( Site 0115) Morristown, New Jersey | |
| Avera Cancer Institute - Aberdeen ( Site 0123) Aberdeen, South Dakota | |
| Avera Cancer Institute - Marshall ( Site 0122) Marshall, Minnesota | |
| Avera Cancer Institute - Mitchell ( Site 0121) Mitchell, South Dakota | |
| Avera Cancer Institute - Pierre ( Site 0118) Pierre, South Dakota | |
| Avera Cancer Institute - Yankton ( Site 0117) Yankton, South Dakota | |
| Avera Cancer Institute- Research ( Site 0094) Sioux Falls, South Dakota | |
| Bacs-Kiskun Varmegyei Oktatokorhaz-Onkoradiologiai Kozpont ( Site 0752) Kecskemét, Bács-Kiskun county | |
| Baltimore Veterans Affairs Medical Center ( Site 0069) Baltimore, Maryland | |
| Baskent University Dr. Turgut Noyan Research and Training Center-ONCOLOGY ( Site 1554) Adana, | |
| Beijing Cancer hospital-Urinary Surgery ( Site 0395) Beijing, Beijing Municipality | |
| Beijing Friendship Hospital Affiliate of Capital University ( Site 0396) Beijing, Beijing Municipality | |
| Bell Land General Hospital ( Site 0913) Sakai, Osaka | |
| Blue Ridge Cancer Care ( Site 0004) Roanoke, Virginia | |
| Bradford Hill Norte ( Site 0357) Antofagasta, | |
| Bradfordhill-Clinical Area ( Site 0351) Santiago, Region M. de Santiago | |
| Bruce W. Carter Veterans Affairs Medical Center ( Site 0082) Miami, Florida | |
| CIO - Centro de Inmuno-Oncología de Occidente ( Site 1103) Guadalajara, Jalisco | |
| Centre Eugène Marquis Rennes - Centre de Lutte Contre le Cancer ( Site 0632) Rennes, Ille-et-Vilaine | |
| Centre Hospitalier Universitaire de Nîmes - Institut de Cancérologie du Gard - Hôpital Universitaire ( Site 0630) Nîmes, Gard | |
| Centre Hospitalier de l'Université de Montréal ( Site 0326) Montreal, Quebec | |
| Centre Hospitalier de la Côte Basque ( Site 0633) Bayonne, Pyrenees-Atlantiques | |
| Centre Intégré de Santé et de Services Sociaux de la Montérégie-Centre ( Site 0328) Greenfield Park, Quebec | |
| Centre Jean Perrin - Centre Régional de Lutte contre le Cancer d'Auvergne ( Site 0629) Clermont-Ferrand, Puy-de-Dome | |
| Centre Oscar Lambret ( Site 0634) Lille, Ain | |
| Centre intégré de cancérologie du CHU de Québec Université Laval, Hôpital de l'Enfant-Jésus ( Site 0327) Québec, Quebec | |
| Centre intégré universitaire de santé et de services sociaux de l'Estrie - Centre Hospitalier Univer ( Site 0329) Sherbrooke, Quebec | |
| Centro de Investigacion Clinica de Oaxaca ( Site 1109) Mexico City, Mexico City | |
| Centrum Onkologii im. Prof. Franciszka Lukaszczyka ( Site 1302) Bydgoszcz, Kuyavian-Pomeranian Voivodeship | |
| Chang Gung Medical Foundation-Linkou Branch-Medical Oncology ( Site 1504) Taoyuan, | |
| Charing Cross Hospital-Oncology Research ( Site 1606) London, Hammersmith and Fulham | |
| Charité Universitaetsmedizin Berlin - Campus Mitte ( Site 0679) Berlin, | |
| China Medical University Hospital-Department of Urology ( Site 1503) Taichung, | |
| Chongqing Three Gorges Central Hospital's ( Site 0426) Chongqing, Chongqing Municipality | |
| Chongqing University Cancer Hospital ( Site 0416) Chongqing, Chongqing Municipality | |
| Chulalongkorn University ( Site 1530) Bangkok, Bangkok | |
| Clinica Colsanitas S.A, Sede Clínica Universitaria Colombia-Center Investigator ( Site 0501) Bogotá, Bogota D.C. | |
| Clinica Universidad Catolica del Maule-Oncology ( Site 0355) Talca, Maule Region | |
| Clinical Research Chile SpA ( Site 0358) Valdivia, Los Ríos Region | |
| Clínica Imbanaco S.A.S ( Site 0509) Cali, Valle del Cauca Department | |
| Clínica Sánchez Ferrer ( Site 1261) Trujillo, La Libertad | |
| Clínica de Neoplasias Litoral ( Site 0305) Itajaí, Santa Catarina | |
| Colorado Clinical Research ( Site 0067) Lakewood, Colorado | |
| Complexo Hospitalario Universitario de Ourense ( Site 1426) Ourense, Orense | |
| Comprehensive Cancer Centers of Nevada ( Site 0010) Las Vegas, Nevada | |
| Cross Cancer Institute ( Site 0332) Edmonton, Alberta | |
| Debreceni Egyetem Klinikai Kozpont-Onkológiai Klinika ( Site 0758) Debrecen, | |
| Dubbo Hospital ( Site 0235) Dubbo, New South Wales | |
| Dunedin Hospital-Southern Blood and Cancers Service ( Site 1203) Dunedin, Otago | |
| ETZ Elisabeth-Internal Medicine ( Site 1160) Tilburg, North Brabant | |
| Ehime University Hospital ( Site 0918) Tōon, Ehime | |
| Emek Medical Center ( Site 0830) Afula, | |
| Faculty of Medicine - Khon Kaen University ( Site 1526) Muang, Changwat Khon Kaen | |
| Faculty of Medicine Siriraj Hospital ( Site 1531) Bangkoknoi, Bangkok | |
| Fakultni nemocnice Olomouc-Onkologicka klinika ( Site 0555) Olomouc, Olomouc Region | |
| Fakultni nemocnice Ostrava-Klinika onkologicka ( Site 0554) Ostrava, Moravian-Silesian Region | |
| Fakultni nemocnice v Motole-Onkologicka klinika 2. LF UK a FN Motol ( Site 0551) Prague, Praha 5 | |
| Filios Alta Medicina ( Site 1106) Monterrey, Nuevo León | |
| First Huai'an Hospital Affiliated to Nanjing Medical University ( Site 0436) Huaian, Jiangsu | |
| Florida Cancer Specialists - South ( Site 7003) Fort Myers, Florida | |
| Fondazione IRCCS Istituto Nazionale dei Tumori-Struttura Complessa Oncologia Medica 1 ( Site 0877) Milan, Lombardy | |
| Franciscus Gasthuis & Vlietland, Locatie Vlietland ( Site 1151) Schiedam, South Holland | |
| Fred Hutchinson Cancer Center ( Site 0013) Seattle, Washington | |
| Fudan University Shanghai Cancer Center-Urology department ( Site 0376) Shanghai, Shanghai Municipality | |
| Fukushima Medical University Hospital ( Site 0933) Fukushima, | |
| Fundacion Centro Oncologico de Integración Regional-Medical Oncology ( Site 0204) Mendoza, | |
| Fundación Arturo López Pérez ( Site 0353) Santiago, Region M. de Santiago | |
| Fundación Cardiovascular de Colombia ( Site 0503) Piedecuesta, Santander Department | |
| Fundación Instituto Valenciano de Oncología-Oncologico ( Site 1430) Valencia, Valenciana, Comunitat | |
| Fundación Valle del Lili ( Site 0505) Cali, Valle del Cauca Department | |
| Gifu University Hospital ( Site 0910) Gifu, | |
| Greenebaum Comprehensive Cancer Center ( Site 0049) Baltimore, Maryland | |
| Gulhane Egitim Arastirma Hastanesi ( Site 1558) Ankara, | |
| Gustave Roussy ( Site 0626) Villejuif, Val-de-Marne | |
| HELIOS Kliniken Schwerin ( Site 0694) Schwerin, Mecklenburg-Vorpommern | |
| HOSPITAL UNIVERSITARIO VIRGEN DEL ROCIO-Medical Oncology ( Site 1428) Seville, | |
| Hacettepe Universite Hastaneleri-oncology hospital ( Site 1551) Ankara, | |
| Hadassah Medical Center ( Site 0833) Jerusalem, | |
| Haga Ziekenhuis locatie Leyweg-Oncology ( Site 1164) The Hague, South Holland | |
| Hattiesburg Clinic Hematology/Oncology ( Site 0120) Hattiesburg, Mississippi | |
| Henry Ford Hospital ( Site 0015) Detroit, Michigan | |
| Hiroshima University Hospital ( Site 0916) Hiroshima, | |
| Hokkaido University Hospital ( Site 0931) Sapporo, Hokkaido | |
| Hopitaux Universitaires de Strasbourg ( Site 0627) Strasbourg, Bas-Rhin | |
| Hospital Aleman-Oncology ( Site 0207) Buenos Aires, | |
| Hospital Británico de Buenos Aires-Oncology ( Site 0202) Ciudad Autónoma de Buenos Aires, Buenos Aires | |
| Hospital Felicio Rocho ( Site 0317) Belo Horizonte, Minas Gerais | |
| Hospital Jerez de la Frontera ( Site 1427) Jerez de la Frontera, Cadiz | |
| Hospital Kuala Lumpur-Radiotherapy and Oncology ( Site 1078) Kuala Lumpur, | |
| Hospital Lucus Augusti-Oncology ( Site 1432) Lugo, | |
| Hospital Mario Penna ( Site 0309) Belo Horizonte, Minas Gerais | |
| Hospital Santa Rita de Cassia-Centro de Pesquisa Clínica ( Site 0320) Vitória, Espírito Santo | |
| Hospital Sultan Ismail ( Site 1081) Johor Bahru, Johor | |
| Hospital Universitario "Dr. Jose Eleuterio Gonzalez"-Servicio de Oncología ( Site 1107) Monterrey, Nuevo León | |
| Hospital Universitario 12 de Octubre-Medical Oncology ( Site 1433) Madrid, Madrid, Comunidad de | |
| Hospital Universitario Ramón y Cajal-Medical Oncology ( Site 1431) Madrid, Madrid, Comunidad de | |
| Hospital Universitário Evangélico Mackenzie-Centro de Oncologia Mackenzie ( Site 0314) Curitiba, Paraná | |
| Hospital Universitário São Francisco de Assis - Bragança Paulista ( Site 0308) Bragança Paulista, São Paulo | |
| Hospital of the University of Occupational and Environmental Health, Japan ( Site 0921) Kitakyushu, Fukuoka | |
| Huadong Hospital Affiliated to Fudan University-Urology ( Site 0388) Shanghai, Shanghai Municipality | |
| Hubei Cancer Hospital-Urinary surgery ( Site 0406) Wuhan, Hubei | |
| Hunan Cancer Hospital ( Site 0405) Changsha, Hunan | |
| Hôpital Européen Georges Pompidou ( Site 0628) Paris, | |
| IC La Serena Research ( Site 0356) La Serena, Coquimbo Region | |
| IMAT S.A.S ( Site 0504) Montería, Departamento de Córdoba | |
| INSTITUTO NACIONAL DE ENFERMEDADES NEOPLASICAS-Medical Oncology ( Site 1256) Lima, | |
| IPOR Instituto Peruano de Oncología & Radioterapia-Centro de Investigación ( Site 1254) Lima, | |
| IRCCS - Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori"-Oncologia Medica ( Site 0879) Meldola, Emilia-Romagna | |
| Instituto Alexander Fleming-Alexander Fleming ( Site 0206) Buenos Aires, Buenos Aires F.D. | |
| Instituto Regional de Enfermedades Neoplasicas del Centro (IREN CENTRO) ( Site 1258) Concepción, Departamento de Junín | |
| Instituto de Investigaciones Clínicas Mar del Plata ( Site 0201) Mar del Plata, Buenos Aires | |
| Istanbul Universitesi Cerrahpasa-Medical Oncology ( Site 1555) Istanbul, | |
| James J. Peters VA Medical Center ( Site 0088) The Bronx, New York | |
| Jiangxi Cancer Hospital ( Site 0386) Nanchang, Jiangxi | |
| Kagawa University Hospital ( Site 0917) Kita, Kagawa-ken | |
| Kagoshima University Hospital ( Site 0929) Kagoshima, | |
| Kaiser Permanente Riverside Medical Center ( Site 0099) Riverside, California | |
| Kanazawa Medical University Hospital ( Site 0909) Mukai-awagasaki, Ishikawa-ken | |
| Kansai Medical University Hospital ( Site 0912) Hirakata, Osaka | |
| Karolinska Universitetssjukhuset Solna ( Site 1478) Stockholm, Stockholm County | |
| Klinikum Wels-Grieskirchen GmbH ( Site 0279) Wels, Upper Austria | |
| Kobe University Hospital ( Site 0914) Kobe, Hyōgo | |
| Koc Universitesi Hastanesi ( Site 1561) Istanbul, | |
| Kuopion Yliopistollinen Sairaala ( Site 0603) Kuopio, Northern Savonia | |
| Kurume University Hospital ( Site 0920) Kurume, Fukuoka | |
| Kyushu University Hospital ( Site 0919) Fukuoka, | |
| M Health Fairview Clinics and Surgery Center ( Site 0019) Minneapolis, Minnesota | |
| MEDICAL COLLEGE OF WISCONSIN ( Site 0020) Milwaukee, Wisconsin | |
| Macquarie University-MQ Health Clinical Trials Unit ( Site 0234) Macquarie University, New South Wales | |
| Masarykuv onkologicky ustav-Klinika komplexni onkologicke pece ( Site 0553) Brno, Brno-mesto | |
| Mazowiecki Szpital Wojewódzki w Siedlcach-Siedleckie Centrum Onkologii ( Site 1310) Siedlce, Masovian Voivodeship | |
| Meander Medisch Centrum ( Site 1157) Amersfoort, Utrecht | |
| Medical Care and Research SA de CV ( Site 1108) Mérida, Yucatán | |
| Medische Centrum Leeuwarden ( Site 1172) Leeuwarden, Provincie Friesland | |
| Medizinische Universität Graz-Innere Medizin Klin. Abt. Onkologie ( Site 0280) Graz, Styria | |
| Meir Medical Center. ( Site 0832) Kfar Saba, | |
| Memorial Ankara Hastanesi-Medical Oncology ( Site 1557) Ankara, | |
| Metro-Minnesota Community Clinical Oncology ( Site 0014) Saint Louis Park, Minnesota | |
| Miyazaki Prefectural Miyazaki Hospital ( Site 0927) Miyazaki, | |
| Nagano Municipal Hospital ( Site 0932) Nagano, | |
| Nanbu Tokushukai Hospital ( Site 0930) Shimajiri, Okinawa | |
| Nanchong Central Hospital-urology ( Site 0422) Nanchong, Sichuan | |
| Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School-Urology ( Site 0377) Nanjing, Jiangsu | |
| Nara Medical University Hospital ( Site 0915) Kashihara, Nara | |
| National Cancer Centre Singapore ( Site 1377) Singapore, Central Singapore | |
| National Cancer Institute ( Site 1079) Putrajaya, Putrajaya | |
| National Cheng Kung University Hospital-Urology ( Site 1502) Tainan, | |
| National Hospital Organization Kumamoto Medical Center ( Site 0924) Kumamoto, | |
| National Hospital Organization Nagasaki Medical Center ( Site 0923) Ōmura, Nagasaki | |
| National Hospital Organization Oita Medical Center ( Site 0925) Ōita, | |
| National Taiwan University Hospital-Urology ( Site 1506) Taipei, | |
| National University Hospital ( Site 1376) Singapore, Central Singapore | |
| Nederlands Kanker Instituut - Antoni van Leeuwenhoek - NKI-AVL ( Site 1153) Amsterdam, North Holland | |
| Nograd Varmegyei Szent Lazar Korhaz-Onkologia es Sugarterapias Osztaly ( Site 0761) Salgótarján, Nógrád megye | |
| Obras Sociais Irma Dulce ( Site 0302) Salvador, Estado de Bahia | |
| Ochsner Clinic Foundation ( Site 0108) New Orleans, Louisiana | |
| Odense Universitetshospital-Department of oncology ( Site 0579) Odense, Region Syddanmark | |
| Oncosalud-Clinical Research ( Site 1260) Lima, | |
| Ordensklinikum Linz GmbH Elisabethinen-Urologie ( Site 0276) Linz, Upper Austria | |
| Oregon Health and Science University ( Site 0028) Portland, Oregon | |
| Országos Onkológiai Intézet-Urogenitális Tumorok és Klinikai Farmakológiai Osztály ( Site 0756) Budapest, Pest County | |
| Ospedale San Raffaele-Oncologia Medica ( Site 0876) Milan, | |
| Pan American Center for Oncology Trials - Ciudadela ( Site 1351) San Juan, | |
| Peking University First Hospital-Urology ( Site 0390) Beijing, Beijing Municipality | |
| Peter MacCallum Cancer Centre-Parkville Cancer Clinical Trials Unit (PCCTU) ( Site 0230) Melbourne, Victoria | |
| Pontificia Universidad Catolica de Chile-Hemato-Oncology ( Site 0354) Santiago, Region M. de Santiago | |
| Prince of Wales Hospital ( Site 0730) Shatin, | |
| Princess Alexandra Hospital-Cancer Care Serices ( Site 0237) Brisbane, Queensland | |
| Princess Margaret Cancer Centre ( Site 0330) Toronto, Ontario | |
| Puerto Rico Medical Research Center LLC ( Site 1354) Hato Rey, | |
| Queen Mary Hospital ( Site 0727) Hong Kong, | |
| Quemex Medical and Research ( Site 1112) Mexico City, Mexico City | |
| Rabin Medical Center ( Site 0828) Petah Tikva, | |
| Radboudumc-Medical Oncology ( Site 1152) Nijmegen, Gelderland | |
| Ralph H. Johnson VA Health Care System (RHJVAHCS)-Urology ( Site 0083) Charleston, South Carolina | |
| Rambam Health Care Campus-Oncology Division ( Site 0826) Haifa, | |
| Regionalny Szpital Specjalistyczny im. dr. Władyslawa Biegańskiego ( Site 1316) Grudziądz, Kuyavian-Pomeranian Voivodeship | |
| Rigshospitalet ( Site 0576) Copenhagen, Capital Region | |
| Rutgers Cancer Institute of New Jersey ( Site 0033) New Brunswick, New Jersey | |
| SCRI Oncology Partners ( Site 7000) Nashville, Tennessee | |
| Saga-Ken Medical Centre Koseikan ( Site 0922) Saga, Saga-ken | |
| Sahlgrenska Universitetssjukhuset ( Site 1479) Gothenburg, Västra Götaland County | |
| Samsun Medical Park Hastanesi-medical oncology ( Site 1560) Samsun, | |
| Samsung Medical Center ( Site 1405) Seoul, | |
| Sanatorio Parque ( Site 0208) Rosario, Santa Fe Province | |
| Sapporo Medical University Hospital ( Site 0902) Sapporo, Hokkaido | |
| Sarawak General Hospital-Radiotherapy Unit ( Site 1076) Kuching, Sarawak | |
| Second Affiliated hospital of Anhui Medical University-Urology ( Site 0408) Hefei, Anhui | |
| Seoul National University Hospital-Oncology ( Site 1401) Seoul, | |
| Severance Hospital, Yonsei University Health System-Medical oncology ( Site 1404) Seoul, | |
| Sheba Medical Center ( Site 0827) Ramat Gan, | |
| Sociedad De Oncología y Hematología Del Cesar SAS-Oncology ( Site 0502) Valledupar, Cesar Department | |
| Songklanagarind hospital ( Site 1527) Hat Yai, Changwat Songkhla | |
| Southwest Hospital of Third Military Medical University ( Site 0420) Chongqing, Chongqing Municipality | |
| Spaarne Gasthuis - Hoofddorp-Oncology ( Site 1170) Hoofddorp, North Holland | |
| St. Olavs Hospital-Kreftklinikken ( Site 1231) Trondheim, Sor-Trondelag | |
| St. Vincent's University Hospital ( Site 0802) Dublin, Dublin | |
| Stanford Cancer Center ( Site 0036) Palo Alto, California | |
| Suining Central Hospital ( Site 0437) Suining, Sichuan | |
| Sun Yat-sen University Cancer Center-Internal medicine ( Site 0413) Guangzhou, Guangdong | |
| Sunnybrook Research Institute ( Site 0331) Toronto, Ontario | |
| Swietokrzyskie Centrum Onkologii, Samodzielny Publiczny Zakl-Klinika Onkologii Klinicznej, Dzial Ch ( Site 1318) Kielce, Świętokrzyskie Voivodeship | |
| Sykehuset Østfold Kalnes ( Site 1228) Sarpsborg, Østfold fylke | |
| Szpital Wojewódzki im. Mikoaja Kopernika w Koszalinie-Oddzial Dzienny Chemioterapii ( Site 1303) Koszalin, West Pomeranian Voivodeship | |
| TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi-oncology ( Site 1553) Istanbul, | |
| Taipei Veterans General Hospital ( Site 1505) Taipei, | |
| Tallaght University Hospital ( Site 0801) Dublin, | |
| Tampereen yliopistollinen sairaala ( Site 0604) Tampere, Pirkanmaa | |
| Tan Tock Seng Hospital-Medical Oncology ( Site 1378) Singapore, Central Singapore | |
| Tauranga Hospital-Bay of Plenty Clinical Trials Unit ( Site 1201) Tauranga, Bay of Plenty | |
| Texas Oncology - Central/South Texas ( Site 8003) Austin, Texas | |
| Texas Oncology - DFW ( Site 8001) Dallas, Texas | |
| Texas Oncology - Gulf Coast ( Site 8002) Houston, Texas | |
| The Beatson West of Scotland Cancer Centre ( Site 1603) Glasgow, Glasgow City | |
| The Christie NHS Foundation Trust ( Site 1608) Manchester, | |
| The First Affiliated Hospital Of Fujian Medical University-Urology ( Site 0414) Fuzhou, Fujian | |
| The First Affiliated Hospital of Chongqing Medical University ( Site 0427) Chongqing, Chongqing Municipality | |
| The First Affiliated Hospital of Guangzhou Medical University ( Site 0412) Guangzhou, Guangdong | |
| The First Affiliated Hospital of Ningbo University ( Site 0383) Ningbo, Zhejiang | |
| The First Affiliated Hospital of Wenzhou Medical University-Urology Surgery ( Site 0379) Wenzhou, Zhejiang | |
| The First Affiliated Hospital of Xi'an Jiaotong University-Oncology ( Site 0393) Xi'an, Shaanxi | |
| The First Affiliated hospital of Xiamen University-Urology ( Site 0415) Xiamen, Fujian | |
| The First Hospital of Jiaxing-urology ( Site 0380) Jiaxing, Zhejiang | |
| The Jikei University Hospital ( Site 0907) Minato, Tokyo | |
| The Ottawa Hospital - General Campus-The Ottawa Hospital Cancer Centre ( Site 0336) Ottawa, Ontario | |
| The Royal Cornwall Hospital ( Site 1610) Truro, England | |
| The Second Affiliated Hospital Of Kunming Medical University ( Site 0429) Kunming, Yunnan | |
| The Second Affiliated Hospital of Xi'an Jiaotong University ( Site 0394) Xi'an, Shaanxi | |
| The Second Hospital of Tianjin Medical University ( Site 0391) Tianjin, Tianjin Municipality | |
| The Third People's Hospital of Chengdu (CDTPH) ( Site 0428) Chengdu, Sichuan | |
| The University of Osaka Hospital ( Site 0911) Suita, Osaka | |
| Tianjin Medical University Cancer Institute & Hospital ( Site 0392) Tianjin, Tianjin Municipality | |
| Toho University Sakura Medical Center ( Site 0906) Sakura, Chiba | |
| Tongji Hospital Tongji Medical,Science & Technology ( Site 0407) Wuhan, Hubei | |
| Turku University Hospital-Department of Oncology ( Site 0601) Turku, Southwest Finland | |
| Universitaetsklinikum Hamburg-Eppendorf-Onkologisches Zentrum ( Site 0705) Hamburg, | |
| University College London Hospital ( Site 1612) London, London, City of | |
| University Hospitals Cleveland Medical Center ( Site 0043) Cleveland, Ohio | |
| University Malaya Medical Centre ( Site 1077) Lembah Pantai, Kuala Lumpur | |
| University Of Nebraska Medical Center-Oncology/Hematology ( Site 0095) Omaha, Nebraska | |
| University of California, Irvine (UCI) Health - UC Irvine Medical Center ( Site 0040) Orange, California | |
| University of Chicago Medical Center ( Site 0045) Chicago, Illinois | |
| University of Colorado Health - Highlands Ranch Hospital ( Site 0111) Highlands Ranch, Colorado | |
| University of Colorado Health - Lone Tree Medical Center ( Site 0112) Lone Tree, Colorado | |
| University of Illinois at Chicago ( Site 0105) Chicago, Illinois | |
| University of Iowa ( Site 0047) Iowa City, Iowa | |
| University of Kentucky Chandler Medical Center ( Site 0048) Lexington, Kentucky | |
| University of Miami Hospital and Clinics, Sylvester Cancer Center ( Site 0051) Miami, Florida | |
| University of Miyazaki Hospital ( Site 0926) Miyazaki, | |
| University of Virginia Health System ( Site 0054) Charlottesville, Virginia | |
| Universitätsklinikum Bonn-Klinik und Poliklinik für Urologie und Kinderurologie ( Site 0680) Bonn, North Rhine-Westphalia | |
| Universitätsklinikum Jena-Klinik und Poliklinik für Urologie ( Site 0682) Jena, Thuringia | |
| Universitätsklinikum Münster - Albert Schweitzer Campus-Klinik für Urologie ( Site 0678) Münster, North Rhine-Westphalia | |
| Universitätsklinikum Schleswig-Holstein-Klinik für Urologie ( Site 0691) Lübeck, Schleswig-Holstein | |
| VA Portland Health Care System ( Site 0058) Portland, Oregon | |
| VCU Health Adult Outpatient Pavillion ( Site 0061) Richmond, Virginia | |
| Vejle Sygehus ( Site 0578) Vejle, Region Syddanmark | |
| VieCuri Medisch Centrum ( Site 1173) Venlo, Limburg | |
| Washington University School of Medicine-Internal Medicine/Oncology ( Site 0062) St Louis, Missouri | |
| West China Hospital, Sichuan University-Urology Surgery ( Site 0417) Chengdu, Sichuan | |
| Westmead Hospital ( Site 0232) Westmead, New South Wales | |
| Wojewodzki Szpital Zespolony im Ludwika Rydygiera w Toruniu ( Site 1304) Torun, Kuyavian-Pomeranian Voivodeship | |
| Xinjiang Medical University Cancer Hospital - Urumqi-Urology ( Site 0419) Ürümqi, Xinjiang | |
| Yale-New Haven Hospital-Yale Cancer Center ( Site 0064) New Haven, Connecticut | |
| Yantai Yuhuangding Hospital ( Site 0397) Yantai, Shandong | |
| Yokohama City University Medical Center ( Site 0908) Yokohama, Kanagawa | |
| Yunnan Province Cancer Hospital ( Site 0418) Kunming, Yunnan | |
| Zachodniopomorskie Centrum Onkologii ( Site 1311) Szczecin, West Pomeranian Voivodeship | |
| Zhejiang Cancer Hospital ( Site 0435) Hangzhou, Zhejiang | |
| Zhejiang Provincial People's Hospital-Urology ( Site 0378) Hangzhou, Zhejiang | |
| Zhongshan Hospital Fudan University ( Site 0430) Shanghai, Shanghai Municipality | |
| Zuyderland Medical Centre-Trialbureau Interne Geneeskunde ( Site 1163) Sittard-Geleen, Limburg | |
| klinikum rechts der isar der technischen universität münchen-Urologische Klinik und Poliklinik ( Site 0696) Munich, Bavaria |
Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial
ctrrecruit@vcu.edu
NCT06096844
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Inclusion Criteria:
* STEP 1 REGISTRATION
* Patient must be ≥ 70 years of age
* Patient must have histologically or cytologically confirmed non-small cell lung cancer (NSCLC) with PD-L1 Tumor Proportion Score (TPS) range of 1-49%
* Patient must have Stage IIIB, IIIC or IV disease and not be candidates for combined chemo-radiation. NOTE: Prior chemo-radiation therapy (RT) for stage III with recurrence is allowed
* Patient must have a tumor that is negative for EGFR mutation/ALK translocations or other actionable first line mutations in which patients would receive first-line oral tyrosine kinase inhibitors
* Patient must have an Eastern Cooperative Oncology Group (ECOG) Performance Status of 0-2
* Patient must agree not to father children while on study and for 6 months after the last dose of protocol treatment
* Patient must have the ability to understand and the willingness to sign a written informed consent document. Patients with impaired decision-making capacity (IDMC) who have a legally authorized representative (LAR) or caregiver and/or family member available will also be considered eligible
* Absolute neutrophil count (ANC) ≥ 1,500/uL (obtained within 14 days prior to Step 1 registration)
* Platelets ≥ 75,000/uL (obtained within 14 days prior to Step 1 registration)
* Hemoglobin (Hgb) ≥ 8.0 g/dL (obtained within 14 days prior to Step 1 registration)
* Total bilirubin ≤ 1.5 x institutional upper limit of normal (ULN) (obtained within 14 days prior to Step 1 registration)
* Aspartate aminotransferase (AST) (serum glutamic-oxaloacetic transaminase \[SGOT\]) and alanine aminotransferase (ALT) (serum glutamate pyruvate transaminase \[SGPT\]) ≤ 3.0 × institutional ULN (obtained within 14 days prior to Step 1 registration)
* Creatinine clearance (CrCL) ≥ 45 mL/min (estimated using Cockcroft-Gault method with actual body weight or measured) (obtained within 14 days prior to Step 1 registration)
* Human immunodeficiency virus (HIV)-infected patients on effective antiretroviral therapy with undetectable viral load within 6 months of Step 1 registration are eligible for this trial
* For patients with evidence of chronic hepatitis B virus (HBV) infection, the HBV viral load must be undetectable on suppressive therapy, if indicated
* Patients with a history of hepatitis C virus (HCV) infection must have been treated and cured. For patients with HCV infection who are currently on treatment, they are eligible if they have undetectable HCV viral
* Patients with a prior or concurrent malignancy whose natural history or treatment does not have the potential to interfere with the safety or efficacy assessment of the investigational regimen are eligible for this trial
* Patient must be English or Spanish speaking to be eligible for the QOL component of the study
* NOTE: Sites cannot translate the associated GA or QOL forms
* Patient must not have symptomatic central nervous system disease (CNS) metastases. Patients with a clinical history of CNS metastases or cord compression are eligible if they have been definitively treated and are clinically stable for at least 14 days prior to Step 1 registration and off all steroids for at least 24 hours prior to Step 1 registration. Patients with asymptomatic CNS metastases are eligible
* Patient must not have had any prior cytotoxic chemotherapy regimen for metastatic disease. Chemotherapy given in the setting of adjuvant therapy or locally advanced disease is allowed as long as treatment was completed, and they have fully recovered from treatment related adverse events prior to Step 1 registration
* Patient must not have had any prior immunotherapy for metastatic disease. Immunotherapy given in the setting of adjuvant therapy or locally advanced disease is allowed as long as treatment was completed greater than 6 months prior to Step 1 registration
* Patient must not have a history of uncontrolled autoimmune conditions with the following exceptions, which are allowed: alopecia, vitiligo, rheumatoid arthritis, psoriasis/psoriatic arthritis, Hashimoto's thyroiditis, lupus, inflammatory bowel disease
* Patient must not be on immunosuppressive medication, including steroids (if doses exceed the equivalent of prednisone 10 mg daily). Short courses of steroids which are discontinued prior to randomization are acceptable. Patients on inhaled, intranasal and/or topical steroids are eligible
* Patient must have baseline imaging done assessing all measurable or non-measurable sites of disease within 45 days prior to Step 1 registration
* Investigator must declare their intended chemotherapy regimen should their patient be randomized to Arm B (doublet versus\[vs\] singlet)
* STEP 2 RANDOMIZATION
* Patient must have completed the baseline Geriatric Assessment (GA) after Step 1 registration and prior to Step 2 randomization DRUG: Carboplatin, PROCEDURE: Computed Tomography, PROCEDURE: Magnetic Resonance Imaging, DRUG: Nab-paclitaxel, DRUG: Paclitaxel, BIOLOGICAL: Pembrolizumab, DRUG: Pemetrexed, PROCEDURE: Positron Emission Tomography, OTHER: Questionnaire Administration
Advanced Lung Non-Small Cell Carcinoma, Stage IIIB Lung Cancer AJCC v8, Stage IIIC Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8
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Show 326 locations
Study Locations
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| Location | Contacts |
|---|---|
| AMG Crystal Lake - Oncology Crystal Lake, Illinois | Site Public Contact - (advocateresearch@advocate.com) |
| AMG Libertyville - Oncology Libertyville, Illinois | Site Public Contact - (advocateresearch@advocatehealth.com) |
| Abbott-Northwestern Hospital Minneapolis, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Adena Regional Medical Center Chillicothe, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Advocate Christ Medical Center Oak Lawn, Illinois | |
| Advocate Good Samaritan Hospital Downers Grove, Illinois | Site Public Contact - (Barbara.barhamand@advocatehealth.com) |
| Advocate Good Shepherd Hospital Barrington, Illinois | |
| Advocate Illinois Masonic Medical Center Chicago, Illinois | |
| Advocate Lutheran General Hospital Park Ridge, Illinois | |
| Advocate Outpatient Center - Aurora Aurora, Illinois | Site Public Contact - (ncorp@aah.org) |
| Advocate Sherman Hospital Elgin, Illinois | |
| Advocate South Suburban Hospital Hazel Crest, Illinois | |
| Aspirus Cancer Care - Stevens Point Stevens Point, Wisconsin | Site Public Contact - (Beth.Knetter@aspirus.org) |
| Aspirus Cancer Care - Wisconsin Rapids Wisconsin Rapids, Wisconsin | |
| Aspirus Cancer Care-Antigo-Volm Cancer Center Antigo, Wisconsin | Site Public Contact - (Juli.Alford@aspirus.org) |
| Aspirus Cancer Care-Rhinelander-James Beck Cancer Center Rhinelander, Wisconsin | Site Public Contact - (Beth.Knetter@aspirus.org) |
| Aspirus Cancer Care-Wausau Wausau, Wisconsin | |
| Aspirus Medford Hospital Medford, Wisconsin | Site Public Contact - (Beth.Knetter@aspirus.org) |
| Asplundh Cancer Pavilion Willow Grove, Pennsylvania | |
| Atrium Medical Center-Middletown Regional Hospital Franklin, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Aultman Health Foundation Canton, Ohio | Site Public Contact - (ClinicalReserachDept@aultman.com) |
| Aurora Bay Area Medical Group-Marinette Marinette, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora BayCare Medical Center Green Bay, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Cancer Care-Grafton Grafton, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Cancer Care-Kenosha South Kenosha, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Cancer Care-Milwaukee Milwaukee, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Cancer Care-Milwaukee West Wauwatosa, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Cancer Care-Racine Racine, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Cancer Care-Southern Lakes VLCC Burlington, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Health Care Germantown Health Center Germantown, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Medical Center in Summit Summit, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Saint Luke's Medical Center Milwaukee, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Saint Luke's South Shore Cudahy, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Sinai Medical Center Milwaukee, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora West Allis Medical Center West Allis, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Bellin Memorial Hospital Green Bay, Wisconsin | |
| Benefis Sletten Cancer Institute Great Falls, Montana | Site Public Contact - (mccinfo@mtcancer.org) |
| Billings Clinic Cancer Center Billings, Montana | Site Public Contact - (research@billingsclinic.org) |
| Bozeman Health Deaconess Hospital Bozeman, Montana | Site Public Contact - (mccinfo@mtcancer.org) |
| Bronson Battle Creek Battle Creek, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
| Bronson Methodist Hospital Kalamazoo, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
| Bryn Mawr Hospital Bryn Mawr, Pennsylvania | Site Public Contact - (turzoe@mlhs.org) |
| CTCA at Southeastern Regional Medical Center Newnan, Georgia | |
| Cancer Care Center of O'Fallon O'Fallon, Illinois | Site Public Contact - (morganthaler.jodi@mhsil.com) |
| Cancer Care Specialists of Illinois - Decatur Decatur, Illinois | Site Public Contact - (morganthaler.jodi@mhsil.com) |
| Cancer Hematology Centers - Flint Flint, Michigan | Site Public Contact - (wstrong@ghci.org) |
| Cancer and Hematology Centers of Western Michigan - Norton Shores Norton Shores, Michigan | |
| Carle Cancer Center Urbana, Illinois | Site Public Contact - (Research@carle.com) |
| Carle Physician Group-Effingham Effingham, Illinois | Site Public Contact - (Research@carle.com) |
| Carle Physician Group-Mattoon/Charleston Mattoon, Illinois | Site Public Contact - (Research@carle.com) |
| Carle at The Riverfront Danville, Illinois | Site Public Contact - (Research@Carle.com) |
| Case Western Reserve University Cleveland, Ohio | Site Public Contact - (CTUReferral@UHhospitals.org) |
| Community Hospital of Anaconda Anaconda, Montana | Site Public Contact - (mccinfo@mtcancer.org) |
| Community Medical Center Toms River, New Jersey | Site Public Contact - (mccinfo@mtcancer.org) |
| Condell Memorial Hospital Libertyville, Illinois | Site Public Contact - (advocateresearch@advocatehealth.com) |
| Corewell Health Grand Rapids Hospitals - Butterworth Hospital Grand Rapids, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
| Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center Saint Joseph, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
| Corewell Health Lakeland Hospitals - Niles Hospital Niles, Michigan | |
| Corewell Health Lakeland Hospitals - Saint Joseph Hospital Saint Joseph, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
| Corewell Health Reed City Hospital Reed City, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
| Crossroads Cancer Center Effingham, Illinois | Site Public Contact - (morganthaler.jodi@mhsil.com) |
| Dana Farber-Merrimack Valley Methuen, Massachusetts | |
| Dana-Farber Cancer Institute at Boston Medical Center - Brighton Brighton, Massachusetts | |
| Dana-Farber Cancer Institute at Foxborough Foxborough, Massachusetts | |
| Dana-Farber/Brigham and Women's Cancer Center at Milford Regional Milford, Massachusetts | |
| Dana-Farber/Brigham and Women's Cancer Center at South Shore South Weymouth, Massachusetts | |
| Dartmouth Cancer Center - North Saint Johnsbury, Vermont | Site Public Contact - (cancer.research.nurse@hitchcock.org) |
| Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center Lebanon, New Hampshire | Site Public Contact - (cancer.research.nurse@dartmouth.edu) |
| Decatur Memorial Hospital Decatur, Illinois | Site Public Contact - (morganthaler.jodi@mhsil.com) |
| Duluth Clinic Ashland Ashland, Wisconsin | Site Public Contact - (CancerTrials@EssentiaHealth.org) |
| Durham VA Medical Center Durham, North Carolina | |
| ECOG-ACRIN Cancer Research Group Philadelphia, Pennsylvania | Megan A. Baumgart - (megan_baumgart@urmc.rochester.edu) |
| Edwards Comprehensive Cancer Center Huntington, West Virginia | Site Public Contact - (Christina.Cole@chhi.org) |
| Essentia Health - Deer River Clinic Deer River, Minnesota | Site Public Contact - (CancerTrials@EssentiaHealth.org) |
| Essentia Health Cancer Center Duluth, Minnesota | Site Public Contact - (CancerTrials@EssentiaHealth.org) |
| Essentia Health Hibbing Clinic Hibbing, Minnesota | |
| Essentia Health Sandstone Sandstone, Minnesota | Site Public Contact - (CancerTrials@EssentiaHealth.org) |
| Essentia Health Virginia Clinic Virginia, Minnesota | Site Public Contact - (CancerTrials@EssentiaHealth.org) |
| Fairview Southdale Hospital Edina, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Genesee Hematology Oncology PC Flint, Michigan | |
| Genesis Healthcare System Cancer Care Center Zanesville, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Genesys Hurley Cancer Institute Flint, Michigan | Site Public Contact - (wstrong@ghci.org) |
| George Washington University Medical Center Washington D.C., District of Columbia | |
| Glens Falls Hospital Glens Falls, New York | |
| Gundersen Lutheran Medical Center La Crosse, Wisconsin | Site Public Contact - (cancerctr@gundersenhealth.org) |
| Guthrie Medical Group PC-Robert Packer Hospital Sayre, Pennsylvania | |
| HaysMed Hays, Kansas | |
| Highlands Oncology Group Springdale, Arkansas | Site Public Contact - (research@hogonc.com) |
| Highlands Oncology Group - Fayetteville Fayetteville, Arkansas | Site Public Contact - (research@hogonc.com) |
| Highlands Oncology Group - Rogers Rogers, Arkansas | Site Public Contact - (research@hogonc.com) |
| Holy Cross Hospital Fort Lauderdale, Florida | Site Public Contact - (eileen.georgi@holy-cross.com) |
| Hurley Medical Center Flint, Michigan | Site Public Contact - (wstrong@ghci.org) |
| Inspira Medical Center Mullica Hill Mullica Hill, New Jersey | |
| Iowa Methodist Medical Center Des Moines, Iowa | |
| James A. Haley Veterans Affairs Hospital Tampa, Florida | |
| Jefferson Cherry Hill Hospital Cherry Hill, New Jersey | |
| Jefferson Torresdale Hospital Philadelphia, Pennsylvania | |
| Kaiser Permanente Downtown Commons Sacramento, California | |
| Kaiser Permanente Dublin Dublin, California | |
| Kaiser Permanente Fresno Orchard Plaza Fresno, California | |
| Kaiser Permanente Medical Center - Santa Clara Santa Clara, California | |
| Kaiser Permanente Moanalua Medical Center Honolulu, Hawaii | |
| Kaiser Permanente San Leandro San Leandro, California | |
| Kaiser Permanente- Modesto MOB II Modesto, California | |
| Kaiser Permanente-Fremont Fremont, California | |
| Kaiser Permanente-Fresno Fresno, California | |
| Kaiser Permanente-Modesto Modesto, California | |
| Kaiser Permanente-Oakland Oakland, California | |
| Kaiser Permanente-Roseville Roseville, California | |
| Kaiser Permanente-San Francisco San Francisco, California | |
| Kaiser Permanente-Santa Rosa Santa Rosa, California | |
| Kaiser Permanente-Santa Teresa-San Jose San Jose, California | |
| Kaiser Permanente-South Sacramento Sacramento, California | |
| Kaiser Permanente-South San Francisco South San Francisco, California | |
| Kaiser Permanente-Vallejo Vallejo, California | |
| Kaiser Permanente-Walnut Creek Walnut Creek, California | |
| Kaiser San Rafael-Gallinas San Rafael, California | |
| Kansas City Veterans Affairs Medical Center Kansas City, Missouri | |
| Knox Community Hospital Mount Vernon, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Kootenai Clinic Cancer Services - Post Falls Post Falls, Idaho | Site Public Contact - (mccinfo@mtcancer.org) |
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Testing the Addition of an Individualized Vaccine to Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer
ctrrecruit@vcu.edu
NCT03606967
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Inclusion Criteria:
* Patients must have a histologically confirmed diagnosis of metastatic invasive triple negative breast cancer. Patients with clinical and/or radiologic suspicion of metastatic TNBC can be consented prior to this confirmation.
* Estrogen receptor (ER) and progesterone receptor (PR) less than Allred score of 3 OR less than 1% positive staining cells in the invasive component of the tumor.
* HER2 negative by fluorescence in situ hybridization (FISH) or immunohistochemistry (IHC) staining 0 or 1+.
* PD-L1 negative by a Clinical Laboratory Improvement Act (CLIA) approved laboratory using compatible assays appropriate for treatment decisions.
* Patients may have measurable or evaluable disease.
* Patients must be willing to undergo biopsy and have accessible lesions for a new biopsy, or they must have sufficient tissue available from a biopsy performed for standard of care (specifications below). If patient does not have enough archived tissue available, a new biopsy is required. A tumor specimen obtained from relapsed primary, metastatic, or locally advanced sites of disease (if applicable) must be submitted. Acceptable samples include core needle biopsies for deep tumor tissue (minimum 4 cores) or excisional, incisional, punch, or forceps biopsies for cutaneous, subcutaneous, or mucosal lesions. Formalin-fixed, paraffin-embedded (FFPE) tumor specimens in paraffin blocks are preferred; FFPE tumor tissue sections on slides may be provided if sufficient material (15 x 10μ, unstained) is available. Fine-needle aspiration, brushing, cell pellet from pleural effusion, bone metastases, and lavage samples are not acceptable.
* No prior therapy for metastatic TNBC. Patients who have received taxane-based adjuvant therapy are required to have a disease-free interval of at least 12 months after completion of taxane therapy.
* Age \>= 18 years. Because no dosing or adverse event data are currently available on the use of durvalumab (MEDI4736) and tremelimumab in combination with neoantigen vaccine in patients \< 18 years of age, children are excluded from this study, but will be eligible for future pediatric trials
* Eastern Cooperative Oncology Group (ECOG) performance status =\< 1 (Karnofsky \>= 60%).
* Body weight \> 30 kg.
* Must have a life expectancy of at least 12 weeks.
* Absolute neutrophil count \>= 1,500/mcL.
* Platelets \>= 100,000/mcL.
* Hemoglobin \>= 9.0 g/dL.
* Serum bilirubin =\< 1.5 x institutional upper limit of normal.
* Aspartate aminotransferase (AST) (serum glutamic oxaloacetic transaminase \[SGOT\])/alanine aminotransferase (ALT) (serum glutamic pyruvic transaminase \[SGPT\]) =\< 2.5 x institutional upper limit of normal unless liver metastases are present, in which case it must be =\< 5 x institutional upper limit of normal.
* Calculated creatinine clearance \> 40 mL/min by the Cockcroft-Gault formula or by 24-hour urine collection for determination of creatinine clearance.
* Evidence of post-menopausal status or negative urinary or serum pregnancy test for female pre-menopausal patients. Women will be considered post-menopausal if they have been amenorrheic for 12 months without an alternative medical cause. The following age-specific requirements apply:
* Women \< 50 years of age would be considered post-menopausal if they have been amenorrheic for 12 months or more following cessation of exogenous hormonal treatments and if they have luteinizing hormone and follicle-stimulating hormone levels in the post-menopausal range for the institution or underwent surgical sterilization (bilateral oophorectomy or hysterectomy).
* Women \>= 50 years of age would be considered post-menopausal if they have been amenorrheic for 12 months or more following cessation of all exogenous hormonal treatments, had radiation-induced menopause with last menses \> 1 year ago, had chemotherapy-induced menopause with last menses \> 1 year ago, or underwent surgical sterilization (bilateral oophorectomy, bilateral salpingectomy or hysterectomy).
* The effects of durvalumab (MEDI4736) and tremelimumab and neoantigen vaccine on the developing human fetus are unknown. For this reason and because these agents may be teratogenic, women of child-bearing potential must agree to use adequate contraception (hormonal or barrier method of birth control; abstinence) prior to study entry, for the duration of study participation, and through 180 days after completion of durvalumab (MEDI4736) and tremelimumab. Should a woman become pregnant or suspect she is pregnant while she or her partner is participating in this study, she should inform her treating physician immediately.
* Patient is willing and able to comply with the protocol for the duration of the study including undergoing treatment and scheduled visits and examinations including follow up.
* Human immunodeficiency virus (HIV)-positive patients are eligible provided they have a negative viral load, CD4 count \> 250, and are on a stable antiretroviral regimen.
* Ability to understand and the willingness to sign a written informed consent document. Patients with impaired decision-making capacity who have a close caregiver or legal guardian are also eligible with the consent of the caregiver/guardian.
Exclusion Criteria:
* Patients who are not considered to be candidates for carboplatin + gemcitabine for first line therapy of their metastatic triple negative breast cancer are not eligible.
* Patients who have had chemotherapy, radiotherapy (to more than 30% of the bone marrow), or biologic therapy within 30 days (42 days for nitrosoureas or mitomycin C) prior to entering the study.
* Patients who have received prior immunotherapy for metastatic disease.
* Patients who have not recovered from grade \>= 2 adverse events due to prior anti-cancer therapy with the exception of alopecia, vitiligo, and the laboratory values defined in the inclusion criteria.
* Patients with grade \>= 2 neuropathy will be evaluated on a case-by-case basis after consultation with the study physician.
* Patients with grade \>= 2 endocrinological adverse events (AEs), (e.g., hypothyroidism, adrenal insufficiency, hypopituitarism, or diabetes mellitus), must have been on a stable dose of supplemental therapy for at least 2 weeks before screening to be eligible for this study, and the endocrinological AE must be stable in the opinion of the treating physician.
* Patients who are receiving any other investigational agents or who have received an investigational agent within the last 30 days.
* Receipt of live attenuated vaccination within 6 months prior to study entry or within 30 days of receiving durvalumab (MEDI4736) and tremelimumab.
* Note: Patients, if enrolled, should not receive live vaccine whilst receiving study treatment and up to 30 days after the last dose of study treatment.
* Major surgical procedure within 28 days prior to the first dose of durvalumab (MEDI4736) and tremelimumab. Local surgery of isolated lesions for palliative intent is acceptable.
* Current or prior use of immunosuppressive medication within 14 days before the first dose of durvalumab (MEDI4736) or tremelimumab. The following are exceptions to this criterion:
* Intranasal, inhaled, topical steroids or local steroid injections (e.g. intra-articular injection)
* Systemic corticosteroids at physiological doses which are not to exceed 10 mg/day of prednisone or an equivalent corticosteroid
* Steroids as premedication for hypersensitivity reactions (e.g. CT scan premedication)
* Steroids for symptoms from brain metastases as defined.
* Spinal cord compression or active brain metastases and/or carcinomatous meningitis. Subjects who have had brain metastases resected or have received radiation therapy ending at least 4 weeks prior to registration are eligible if they meet all of the following criteria:
* Residual neurological symptoms have resolved to grade =\< 2
* On stable doses of dexamethasone, if applicable and if acceptable in the opinion of the treating physician
* Follow-up MRI performed after surgery or completion of radiation therapy and prior to registration shows no new lesions.
* History of allergic reactions attributed to compounds of similar chemical or biologic composition to durvalumab (MEDI4736) and tremelimumab. Known allergy, or history of serious adverse reaction to vaccines, such as anaphylaxis, hives or respiratory difficulty.
* Mean QT interval corrected for heart rate using Fridericia's formula (QTcF) \>= 470 ms calculated from 3 electrocardiograms (ECGs) (within 15 minutes at 5 \[+/- 3\] minutes apart).
* Uncontrolled intercurrent illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, uncontrolled hypertension, unstable angina pectoris, cardiac arrhythmia, interstitial lung disease, serious chronic gastrointestinal conditions associated with diarrhea, evidence of any acute or chronic viral illness or disease, or psychiatric illness/social situations that would limit compliance with study requirements.
* Pregnant women are excluded from this study because durvalumab (MEDI4736) and tremelimumab has the potential for teratogenic or abortifacient effects. Because there is an unknown but potential risk for adverse events in nursing infants secondary to treatment of the mother with durvalumab (MEDI4736) and tremelimumab, breastfeeding should be discontinued if the mother is treated with durvalumab (MEDI4736) and tremelimumab. These potential risks may also apply to other agents used in this study. A negative serum pregnancy test is required no more than 7 days before study entry.
* Active autoimmune disease that has required systemic treatment in the past 2 years (i.e. with use of disease modifying agents, corticosteroids, or immunosuppressive drugs). Replacement therapy (e.g. thyroxine, insulin, or physiologic corticosteroid replacement therapy for adrenal or pituitary insufficiency, etc.) is not considered a form of systemic treatment.
* History of pneumonitis or interstitial lung disease.
* History of active primary immunodeficiency.
* Active infection including tuberculosis (clinical evaluation that includes clinical history, physical examination, and radiographic findings, and tuberculosis \[TB\] testing in line with local practice), hepatitis B (known positive hepatitis B virus \[HBV\] surface antigen \[HBsAg\] result), or hepatitis C. Patients with a past or resolved HBV infection (defined as the presence of hepatitis B core antibody \[anti-HBc\] and absence of HBsAg) are eligible. Patients positive for hepatitis C (HCV) antibody are eligible only if polymerase chain reaction is negative for HCV ribonucleic acid (RNA).
* The patient with a previous history of non-breast malignancy is eligible for this study only if the patient meets the following criteria for a cancer survivor. A cancer survivor is eligible provided the following criteria are met:
* Patient has undergone potentially curative therapy for all prior malignancies.
* Patients have been considered disease free for at least 1 year (with the exception of basal cell or squamous cell carcinoma of the skin or carcinoma-in-situ of the cervix).
* Patients with a strong likelihood of non-adherence (such as difficulties in adhering to follow-up schedule due to geographic distance from the treatment facility) should not be knowingly registered.
* History of allogeneic organ transplantation. PROCEDURE: Biopsy Procedure, PROCEDURE: Biospecimen Collection, DRUG: Carboplatin, PROCEDURE: Computed Tomography, BIOLOGICAL: Durvalumab, DRUG: Gemcitabine Hydrochloride, PROCEDURE: Magnetic Resonance Imaging, DRUG: Nab-paclitaxel, BIOLOGICAL: Personalized Synthetic Long Peptide Vaccine, DRUG: Poly ICLC, BIOLOGICAL: Sacituzumab Govitecan, BIOLOGICAL: Tremelimumab
Anatomic Stage IV Breast Cancer AJCC v8, Invasive Breast Carcinoma, Metastatic Triple-Negative Breast Carcinoma
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Study Locations
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| Location | Contacts |
|---|---|
| Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center Lebanon, New Hampshire | |
| Johns Hopkins University/Sidney Kimmel Cancer Center Baltimore, Maryland | Site Public Contact - (jhcccro@jhmi.edu) |
| Moffitt Cancer Center Tampa, Florida | Site Public Contact - (ClinicalTrials@moffitt.org) |
| Moffitt Cancer Center - McKinley Campus Tampa, Florida | Site Public Contact - (ClinicalTrials@moffitt.org) |
| Moffitt Cancer Center at Wesley Chapel Wesley Chapel, Florida | Site Public Contact - (ClinicalTrials@moffitt.org) |
| Moffitt Cancer Center-International Plaza Tampa, Florida | Site Public Contact - (ClinicalTrials@moffitt.org) |
| NYP/Weill Cornell Medical Center New York, New York | |
| Ohio State University Comprehensive Cancer Center Columbus, Ohio | Site Public Contact - (Jamesline@osumc.edu) |
| Siteman Cancer Center at Christian Hospital St Louis, Missouri | Site Public Contact - (info@siteman.wustl.edu) |
| Siteman Cancer Center at Saint Peters Hospital City of Saint Peters, Missouri | Site Public Contact - (info@siteman.wustl.edu) |
| Siteman Cancer Center at West County Hospital Creve Coeur, Missouri | Site Public Contact - (info@siteman.wustl.edu) |
| Siteman Cancer Center-South County St Louis, Missouri | Site Public Contact - (info@siteman.wustl.edu) |
| Smilow Cancer Hospital Care Center at Saint Francis Hartford, Connecticut | |
| UC Irvine Health/Chao Family Comprehensive Cancer Center Orange, California | |
| UCHealth University of Colorado Hospital Aurora, Colorado | |
| UM Sylvester Comprehensive Cancer Center at Aventura Aventura, Florida | |
| UM Sylvester Comprehensive Cancer Center at Coral Gables Coral Gables, Florida | |
| UM Sylvester Comprehensive Cancer Center at Deerfield Beach Deerfield Beach, Florida | |
| UM Sylvester Comprehensive Cancer Center at Kendall Miami, Florida | |
| UM Sylvester Comprehensive Cancer Center at Plantation Plantation, Florida | |
| UPMC Hillman Cancer Center Pittsburgh, Pennsylvania | |
| University of California Davis Comprehensive Cancer Center Sacramento, California | |
| University of Miami Miller School of Medicine-Sylvester Cancer Center Miami, Florida | |
| University of Oklahoma Health Sciences Center Oklahoma City, Oklahoma | |
| University of Texas Medical Branch Galveston, Texas | Site Public Contact - (clinical.research@utmb.edu) |
| VCU Massey Comprehensive Cancer Center Richmond, Virginia | Site Public Contact - (CTOclinops@vcu.edu) |
| Wake Forest University Health Sciences Winston-Salem, North Carolina | |
| Wake Forest University at Clemmons Clemmons, North Carolina | |
| Washington University School of Medicine St Louis, Missouri | Site Public Contact - (info@siteman.wustl.edu) |
| Yale University New Haven, Connecticut |