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641 Study Matches
Efficacy and Safety of Benralizumab vs Mepolizumab in Treatment of EGPA (MANDARA) (MANDARA)
ctrrecruit@vcu.edu
Ward, Brant
NCT04157348
HM20018295
drug: Mepolizumab,
drug: Benralizumab
Diseases of Circulatory System (390-459)
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia |
A Clinical Study to Evaluate the Efficacy and Safety of Aramchol in Subjects With NASH (ARMOR)
Lindemuth, Margaret (Maggie) - margaret.lindemuth@vcuhealth.org
Siddiqui, Mohammad, S
NCT04104321
HM20018490
drug: Aramchol
Diseases of Digestive System (520-579)
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Lindemuth, Margaret (Maggie) - (margaret.lindemuth@vcuhealth.org) |
DSC-MRI in Measuring Cerebral Blood Volume for Early Response to Bevacizumab in Recurrent GBM
Hess, Alison - ahess2@vcu.edu
Chen, Zhi-Jian
NCT03115333
HM20021895
Brain and Nervous System
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Hess, Alison - (ahess2@vcu.edu) |
Validating Cell-Based Assays for ABMR After Renal Transplantation (CBA ABMR)
Baldecchi, Mary - mary.baldecchi@vcuhealth.org
Gupta, Gaurav
NCT03916822
HM20019307
Diseases of Genitourinary System (580-629)
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Baldecchi, Mary - (mary.baldecchi@vcuhealth.org) |
Study of Aldafermin (NGM282) in Subjects With Compensated Cirrhosis (ALPINE 4) (ALPINE4)
Lindemuth, Margaret (Maggie) - margaret.lindemuth@vcuhealth.org
Siddiqui, Mohammad, S
NCT04210245
HM20019792
drug: Ngm282
Diseases of Digestive System (520-579)
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Lindemuth, Margaret (Maggie) - (margaret.lindemuth@vcuhealth.org) |
Flexible-Dose, Adjunctive Therapy Trial in Adults With Parkinson s Disease With Motor Fluctuations
Norris, Virginia "Ginger" - virginia.norris@vcuhealth.org
Cloud, Leslie
NCT04542499
HM20019622
drug: Tavapadon (cvl-751)
Diseases of Nervous System and Sense Organs (320-389)
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Norris, Virginia "Ginger" - (virginia.norris@vcuhealth.org) |
Phase II - Long-term Safety and Efficacy in Adults With CDIP (ADHERE+) (ADHERE+)
Smith, LaVon - lavon.smith@vcuhealth.org
Gwathmey, Kelly
NCT04280718
HM20018942
drug: Argx-113
Diseases of Nervous System and Sense Organs (320-389)
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Smith, LaVon - (lavon.smith@vcuhealth.org) |
Efgartigimod Expanded Access for Generalized Myasthenia Gravis
Wilkins, Bridget - bridget.wilkins@vcuhealth.org
Gwathmey, Kelly
NCT04777734
HM20022105
Diseases of Nervous System and Sense Organs (320-389)
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Wilkins, Bridget - (bridget.wilkins@vcuhealth.org) |
Long-Term Safety and Efficacy Outcomes - Previously Administered SHP607 -Extremely Premature Infants
Lessard, Margaret "Meg" - margaret.lessard@vcuhealth.org
Rozycki, Henry
NCT04506619
HM20022198
Certain Conditions Originating in the Perinatal Period (760-779)
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Lessard, Margaret "Meg" - (margaret.lessard@vcuhealth.org) |
Study in PD Patients With Dyskinesia With Combinations of JM-010 and Its Individual Components
Blackwell, Gina, M - gina.blackwell@vcuhealth.org
Cloud, Leslie
NCT04377945
HM20021757
drug: Jm-010,
drug: Buspirone,
drug: Zolmitriptan
Diseases of Nervous System and Sense Organs (320-389)
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Blackwell, Gina, M - (gina.blackwell@vcuhealth.org) |
Saroglitazar Magnesium for the Treatment of Nonalcoholic Steatohepatitis with Fibrosis
Patel, Falgun - falgun.patel@vcuhealth.org
Siddiqui, Mohammad, S
NCT05011305
HM20021644
drug: Saroglitazar magnesium
Diseases of Digestive System (520-579)
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Patel, Falgun - (falgun.patel@vcuhealth.org) |
Phase 2B, Randomized, Double-Blind, Placebo-Controlled - Safety/ Efficacy of Efruxifermin - NASH
Edwards, Megan, C - megan.edwards@vcuhealth.org
Siddiqui, Mohammad, S
NCT04767529
HM20021459
drug: Efruxifermin
Diseases of Digestive System (520-579)
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Edwards, Megan, C - (megan.edwards@vcuhealth.org) |
HEALEY ALS Platform Trial - Master Protocol (MASTER)
HEALEY Center for ALS at Massachusetts General Hospital - healeyalsplatform@mgh.harvard.edu
Gwathmey, Kelly
NCT04297683
HM20022250
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Inclusion Criteria:
• Sporadic or familial ALS diagnosed as clinically possible, probable, lab-supported probable, or definite ALS defined by revised El Escorial criteria.
• Age 18 years or older.
• Capable of providing informed consent and complying with study procedures, in the SI's opinion.
• Time since onset of weakness due to ALS ≤ 24 months at the time of the Master Protocol Screening Visit.
• Vital Capacity ≥ 50% of predicted capacity at the time of the Master Protocol Screening Visit measured by Slow Vital Capacity (SVC), or, if required due to pandemic-related restrictions, Forced Vital Capacity (FVC) measured in person.
• Participants must either not take riluzole or be on a stable dose of riluzole for ≥ 30 days prior to the Master Protocol Screening Visit.
• Participants must either not take edaravone or have completed at least one cycle (typically 14 days) of edaravone prior to the Master Protocol Screening Visit.
• Participants must have the ability to swallow pills and liquids at the time of the Master Protocol Screening Visit and, in the SI's opinion, have the ability to swallow for the duration of the study.
• Geographically accessible to the site.
Exclusion Criteria:
• Clinically significant unstable medical condition (other than ALS) that would pose a risk to the participant, according to SI's judgment (e.g., cardiovascular instability, systemic infection), or clinically significant laboratory abnormality or EKG changes. Clinically significant abnormal liver or kidney function is exclusionary. The following values \[alanine aminotransferase (ALT) or aspartate aminotransferase (AST) \> 3 times the upper limit of normal (ULN) or estimated Glomerular Filtration Rate (eGFR) \< 30 mL/min/1.73m2\] are exclusionary regardless of clinical symptoms.
• Presence of unstable psychiatric disease, cognitive impairment, dementia or substance abuse that would impair ability of the participant to provide informed consent, in the SI's opinion.
• Active cancer or history of cancer, except for the following: basal cell carcinoma or successfully treated squamous cell carcinoma of the skin, cervical carcinoma in situ, prostatic carcinoma in situ, or other malignancies curatively treated and with no evidence of disease recurrence for at least 3 years.
• Use of investigational treatments for ALS (off-label use or active participation in a clinical trial) within 5 half-lives (if known) or 30 days (whichever is longer) prior to the Master Protocol Screening Visit.
• Exposure at any time to any gene therapies under investigation for the treatment of ALS (off-label use or investigational).
• If female, breastfeeding, known to be pregnant, planning to become pregnant during the study, or of child-bearing potential and unwilling to use effective contraception, for the duration of the trial and for 3 months, or as specified in each RSA, after discontinuing study treatment.
• If male of reproductive capacity, unwilling to use effective contraception for the duration of the trial and for 3 months, or as specified in each RSA, after discontinuing study treatment.
• Anything that would place the participant at increased risk or preclude the participant's full compliance with or completion of the study, in the SI's opinion.
• If a participant is being re-screened, the disqualifying condition has not been resolved, or the mandatory wash-out duration has not occurred.
DRUG: Zilucoplan, DRUG: Verdiperstat, DRUG: CNM-Au8, DRUG: Pridopidine, DRUG: SLS-005 Trehalose, DRUG: ABBV-CLS-7262, DRUG: DNL343, DRUG: NUZ-001
Amyotrophic Lateral Sclerosis
ALS, Placebo-Controlled, Double-Blind, Master Protocol, Lou Gehrig's Disease
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Show 74 locations
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| Location | Contacts |
|---|---|
| Atrium Health Charlotte, North Carolina | Cynthia Lary - (cynthia.lary@atriumhealth.org) Meha Patel - (Meha.Patel@atriumhealth.org) |
| Augusta University Augusta, Georgia | |
| Barrow Neurological Institute Phoenix, Arizona | |
| Beth Israel Deaconess Medical Center Boston, Massachusetts | Teresa Capella - (tcapella@bidmc.harvard.edu) |
| Cedars-Sinai Medical Center Los Angeles, California | |
| Cleveland Clinic Cleveland, Ohio | Emily Delettang - (delette@ccf.org) |
| Columbia University New York, New York | |
| Dartmouth-Hitchcock Medical Center Lebanon, New Hampshire | Gina Kersey - (gina.e.kersey@hitchcock.org) |
| Dent Neurologic Institute Amherst, New York | |
| Duke University Durham, North Carolina | |
| Essentia Health Duluth, Minnesota | Brent Gavin - (Brent.Gavin@essentiahealth.org) |
| Forbes Norris MDA/ALS Research Center, California Pacific Medical Center San Francisco, California | Daniela Sanchez - (Daniela.Sanchez@sutterhealth.org) |
| George Washington University Washington D.C., District of Columbia | |
| Georgetown University Washington D.C., District of Columbia | Cate Ledoux - (csl83@georgetown.edu) |
| Hackensack University Medical Center Hackensack, New Jersey | |
| Henry Ford Health System Novi, Michigan | Maria Stotland - (mstotla1@hfhs.org) |
| Hospital for Special Care New Britain, Connecticut | Honora Dalamagas - (hdalamagas@hfsc.org) |
| Houston Methodist Houston, Texas | |
| Indiana University Health Indianapolis, Indiana | |
| Jefferson Weinberg ALS Center, Thomas Jefferson University Philadelphia, Pennsylvania | Gemma Krautzel - (gemma.krautzel@jefferson.edu) |
| Johns Hopkins University Baltimore, Maryland | |
| Kaiser Permanente Los Angeles Medical Center Los Angeles, California | |
| Lehigh Valley Health Network Allentown, Pennsylvania | |
| Lewis Katz School of Medicine at Temple University Philadelphia, Pennsylvania | Kathleen Hatala - (kathleen.hatala@tuhs.temple.edu) Christine Barr - (christine.barr@tuhs.temple.edu) |
| Loma Linda University Health Loma Linda, California | |
| Massachusetts General Hospital Boston, Massachusetts | Mackenzie DeMello - (MGHsiteHealeyPlatform@mgh.harvard.edu) |
| Mayo Clinic - Rochester Rochester, Minnesota | |
| Mayo Clinic Florida Jacksonville, Florida | |
| Mayo Clinic Scottsdale Scottsdale, Arizona | Alissa Bojko - (Bojko.alissa@mayo.edu) |
| Medical College of Wisconsin Milwaukee, Wisconsin | |
| Neurology Associates, P.C./Somnos Clinical Research Lincoln, Nebraska | |
| Northwestern University Chicago, Illinois | |
| Nova Southeastern University Davie, Florida | Donovan Mott - (Donovan.mott@nova.edu) |
| Ochsner Health System New Orleans, Louisiana | |
| Penn State Hershey Hershey, Pennsylvania | |
| Providence Brain and Spine Institute ALS Center Portland, Oregon | |
| SUNY Upstate Syracuse, New York | Lena Deb - (debl@upstate.edu) |
| Saint Alphonsus Regional Medical Center Boise, Idaho | |
| Saint Louis University St Louis, Missouri | |
| Spectrum Health/Corewell Health Grand Rapids, Michigan | |
| Stony Brook University Hospital Stony Brook, New York | |
| Swedish Medical Center Englewood, Colorado | |
| Texas Neurology Dallas, Texas | Amanda Pinal - (apinal@texasneurology.com) |
| The Ohio State University Columbus, Ohio | Kaneshia Hives - (kaneshia.hives@osumc.edu) Atchayah Balakrishna - (atchayah.balakrishna@osumc.edu) |
| University of Arkansas for Medical Sciences Little Rock, Arkansas | |
| University of California, Irvine Irvine, California | |
| University of California, San Francisco San Francisco, California | |
| University of Chicago Chicago, Illinois | |
| University of Cincinnati Cincinnati, Ohio | Sara Reiber - (searss2@ucmail.uc.edu) |
| University of Colorado Denver, Colorado | |
| University of Florida Gainesville, Florida | |
| University of Iowa Hospitals and Clinics Iowa City, Iowa | Emily Anderson - (emily-anderson@uiowa.edu) |
| University of Kansas Medical Center Kansas City, Kansas | Nicholas Staudenmier - (nstaudenmier@kumc.edu) |
| University of Kentucky Lexington, Kentucky | |
| University of Massachusetts Medical School North Worcester, Massachusetts | Catherine Douthwright - (ALSresearch@umassmed.edu) Reylyn Tanchiatco - (ALSresearch@umassmed.edu) |
| University of Miami Miami, Florida | |
| University of Michigan Ann Arbor, Michigan | Jayna Duell - (jkballar@med.umich.edu) |
| University of Minnesota Medical School Minneapolis, Minnesota | |
| University of Missouri Health Care Columbia, Missouri | Meghan Jo Willis - (willismj@health.missouri.edu) |
| University of Nebraska Medical Center Omaha, Nebraska | Katelyn Hilz - (katelyn.hilz@unmc.edu) |
| University of North Carolina Chapel Hill, North Carolina | |
| University of Penn Philadelphia, Pennsylvania | |
| University of Pittsburg Medical Center Pittsburgh, Pennsylvania | Research Coordinator - (ALSRES@pitt.edu) |
| University of South Florida Tampa, Florida | |
| University of Southern California Los Angeles, California | Salma Akhter - (salma.akhter@med.usc.edu) |
| University of Utah Salt Lake City, Utah | |
| University of Virginia Charlottesville, Virginia | |
| University of Washington Seattle, Washington | Kinsey Chapman - (kinseyc@uw.edu) |
| Uthscsa San Antonio, Texas | |
| Vanderbilt University Medical Center Nashville, Tennessee | Diana Davis - (diana.davis@vumc.org) |
| Virginia Commonwealth University Richmond, Virginia | |
| Wake Forest Health Science Winston-Salem, North Carolina | Mozhdeh Marandi - (mozhdeh.marandi@advocatehealth.org) |
| Washington University School of Medicine St Louis, Missouri | Research Coordinator - (als@wustl.edu) |
| Yale University New Haven, Connecticut |
Open-label Trial in Parkinson s Disease
Norris, Virginia "Ginger" - virginia.norris@vcuhealth.org
Cloud, Leslie
NCT04760769
HM20020944
drug: Tavapadon (cvl-751)
Diseases of Nervous System and Sense Organs (320-389)
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Norris, Virginia "Ginger" - (virginia.norris@vcuhealth.org) |
Cognitive Support Technology for Postsecondary Students with Autism Spectrum Disorder
Inge, Katherine, J - kinge@vcu.edu
Inge, Katherine, J
NCT04980963
HM20019035
Mental Disorders (290-319)
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Inge, Katherine, J - (kinge@vcu.edu) |
Evaluating the Acute Effect of Vaping on Food Intake
ctrrecruit@vcu.edu
Cobb, Caroline
NCT04219189
HM20018382
Any Site
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia |
Treatment of GVHD in HSCT)Recipients Using AAT + Corticosteroids Compared With Corticosteroids Alone
Candler, Kathryn, S. - kcandler@vcu.edu
Clark, William, B
NCT04167514
HM20020328
drug: Alpha-1 anti-tripsin (aat)
Other Hematopoietic
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Candler, Kathryn, S. - (kcandler@vcu.edu) |
Efficacy and Safety of Inebilizumab in Adults with Myasthenia Gravis (MINT) (MINT)
Wilkins, Bridget - bridget.wilkins@vcuhealth.org
Gwathmey, Kelly
NCT04524273
HM20019552
drug: Inebilizumab
Diseases of Nervous System and Sense Organs (320-389)
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Wilkins, Bridget - (bridget.wilkins@vcuhealth.org) |
Clofazimine - Single Patient, Expanded Access
Lessard, Margaret "Meg" - margaret.lessard@vcuhealth.org
Schechter, Michael, S
19468
HM20024709
drug: Clofazimine
Diseases of Respiratory System (460-519), Infectious and Parasitic Diseases (001-139)
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Lessard, Margaret "Meg" - (margaret.lessard@vcuhealth.org) |
CIMR Neuromuscular Research Biobank (NRB-0001)
Nicholas Johnson - nicholas.johnson@vcuhealth.org
NCT05434572
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Inclusion Criteria:
* Willing and able to give informed consent
* Positive diagnosis or suspected diagnosis of neuromuscular disease, or
* Family history of neuromuscular disease, or
* Healthy volunteer
* Age Neonates-75
Exclusion Criteria:
* Unwilling to sign consent Neuromuscular Diseases, Neuromuscular Disorder, Neuromuscular Diseases in Children
Neuromuscular, Research Repository, Biobank, Neuromuscular Disorder
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Carino Jennings - (carino.garza@vcuhealth.org) |
Safe and Timely Antithrombotic Removal - Ticagrelor (STAR-T) (STAR-T)
Susan Magosin, RN - smagosin@cytosorbents.com
NCT04976530
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Inclusion Criteria:
• Male or female 18 years of age or older, with documented full, written informed consent
• Requiring cardiothoracic (CT) surgery with cardiopulmonary bypass (CPB) within two days of ticagrelor discontinuation (day of last dose = day 0)
Exclusion Criteria:
• CT surgery occurring 3 days or greater following ticagrelor discontinuation
• Heart-lung transplant procedures
• Procedures for ventricular assist device (implant/revision of LVAD or RVAD)
• Pre-existing conditions that pose a known risk for bleeding (i.e., HITT, perioperative platelet count < 50,000u/L, hemophilia, and INR >1.5)
• Prohibited concomitant antithrombotic medications as defined in the study protocol
• Acute sickle cell crisis
• Known allergy to device components
• Active (untreated) systemic infection
• History of major organ transplantation and those currently receiving immunosuppressive medication or who are profoundly immune suppressed
• Women with positive pregnancy test during current admission or who are breast-feeding
• Life expectancy <30 days
• Inability to comply with requirements of the study protocol
• Treatment with investigational drug or device within 30 days of current surgery
• Previous enrollment in this trial
Device: DrugSorb-ATR system, Device: Sham comparator
Hemorrhage, Surgical, Blood Loss, Surgical, Blood Loss, Postoperative, Hemorrhage Postoperative
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Show 37 locations
Study Locations
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| Location | Contacts |
|---|---|
| Advent Health Orlando, Florida | Sandra Houser, BSN, RN |
| Baptist Hospital of Miami Miami, Florida | |
| Baylor Scott & White The Heart Hospital Plano Plano, Texas | Megan White, MS |
| Beth Israel Deaconess Medical Center Boston, Massachusetts | Debbie Conboy, RN |
| Bryan Medical Center Lincoln, Nebraska | |
| Carilion Clinic Roanoke, Virginia | Ambili John |
| Emory Saint Joseph's Hospital Atlanta, Georgia | |
| Emory University Hospital Midtown/Emory School of Medicine Atlanta, Georgia | |
| Hamilton General Hospital, Hamilton Health Sciences Corporation Hamilton, Ontario | Leah Hayward, MSc |
| Henry Ford Health System Novi, Michigan | |
| Institut universitaire de cardiologie et de pneumologie de Québec - Université Laval Québec, Quebec | Annie Bergeron |
| Jersey Shore University Medical Center Neptune City, New Jersey | Anne DeToro, RN |
| Kingston Health Sciences Centre Kingston, Ontario | Debbie DuMerton |
| London Health Sciences Centre, University Hospital London, Ontario | Stephanie Fox, BA, RRT |
| Lutheran Medical Group Fort Wayne, Indiana | Sharon Eichman, RN |
| Massachusetts General Hospital Boston, Massachusetts | Annika Gallandt |
| Medical University of South Carolina Charleston, South Carolina | Morgan Overstreet, MSc |
| Medstar Health Research Institute Hyattsville, Maryland | Kate Mahoney |
| Montreal Heart Institute Montreal, Quebec | Alexandre Bergeron |
| New York University Langone Health New York, New York | Lucy Lannan |
| Piedmont Heart Institute Atlanta, Georgia | |
| Rhode Island Hospital Providence, Rhode Island | Lori-Ann DeSimone, RN |
| St. Boniface Hospital Winnipeg, Manitoba | David Kent |
| St. Luke's Hospital of Kansas City Kansas City, Missouri | |
| St. Michael's Hospital, Unity Health Toronto Toronto, Ontario | Samson Moses |
| The Medical College of Wisconsin, Inc. Milwaukee, Wisconsin | James Zelten |
| University Hospitals, Cleveland Medical Center Cleveland, Ohio | Stacey Mazzurco, RN |
| University of California, Davis Medical Center Sacramento, California | Journne Herrera |
| University of Iowa Iowa City, Iowa | Cody Poe, MS |
| University of Maryland Medical Center Baltimore, Maryland | Manal Al-Suqi |
| University of Minnesota Minneapolis, Minnesota | Nicholas Lemke |
| University of Mississippi Jackson, Mississippi | Stephanie Moore, RN |
| University of Vermont Medical Center Burlington, Vermont | Megan Sesera, RN |
| University of Wisconsin-Madison Madison, Wisconsin | Kaelin M Grant |
| VCU Medical Center Richmond, Virginia | Jinfeng Han |
| Virtua Health Camden, New Jersey | Danielle Connors |
| Yale New Haven Hospital New Haven, Connecticut | Ricarda Tomlin |
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
Angie Lee - angie.lee@stryker.com
NCT03072927
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Inclusion Criteria:
* Medicare beneficiaries receiving MILD or interspinous process decompression
* Diagnosis of LSS with NC
Exclusion Criteria:
* Patients that have received a laminectomy, laminotomy, fusion, interspinous process decompression, or MILD in the lumbar region during the 12 months prior to the index date DEVICE: MILD, DEVICE: Interspinous Process Decompression
Lumbar Spinal Stenosis
Lumbar Spinal Stenosis, Interspinous process decompression, MILD, Medicare, Medicare Advantage
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Show 2218 locations
Study Locations
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| Location | Contacts |
|---|---|
| 877-446-6724 Bayonne, New Jersey | |
| AA Spine & Pain Clinic Anchorage, Alaska | |
| AHCMG Sugery Center Germantown Germantown, Wisconsin | |
| AHN Grove City Grove City, Pennsylvania | |
| AMITA Health Adventist Medical Center Hinsdale Hinsdale, Illinois | |
| AMITA Health St. Alexius Medical Center Hoffman Estates Hoffman Estates, Illinois | |
| AMITA St. Francis Hospital Evanston, Illinois | |
| AOS Surgery Center Augusta, Georgia | |
| APAC Surgery Center, II Crown Point, Indiana | |
| ASC For Pain Relief, LLC Evansville, Indiana | |
| ASC at St. Francis Colorado Springs, Colorado | |
| Abilene Ctr For Ortho and Multi Abilene, Texas | |
| Abilene Spine and Joint Surgery Center Abilene, Texas | |
| Abington Memorial Hospital Abington, Pennsylvania | |
| Access Surgery Center Egg Harbor, New Jersey | |
| Acute & Chronic Pain and Spine Center Ambulatory Surgery Center Amarillo, Texas | |
| Adena Greenfield Medical Center Greenfield, Ohio | |
| Adena Health System Chillicothe, Ohio | |
| Adena Pike Medical Center Waverly, Ohio | |
| Adirondack Health Saranac Lake, New York | |
| Advance Spine Ctr of Wisconsin Neenah, Wisconsin | |
| Advance Surg Instu of Evansville Evansville, Indiana | |
| Advanced Ambulatory Surgery Center Chicago, Illinois | |
| Advanced Asc Altamonte Springs, Florida | |
| Advanced Interventional Pain Katy, Texas | |
| Advanced Joint and Spine Instu Orlando, Florida | |
| Advanced Pain Institute Treatment Center Hammond, Louisiana | |
| Advanced Pain Institute of Texas Lewisville, Texas | |
| Advanced Pain Management Rancho Mirage, California | |
| Advanced Pain Management and Wellness Center Jupiter, Florida | |
| Advanced Pain Medicine Assocs Wichita, Kansas | |
| Advanced Pain Mgmt Spclsts Fort Myers, Florida | |
| Advanced Pain Modalities Chandler, Arizona | |
| Advanced Pain Solutions Fresno, California | |
| Advanced Regional Surgery Center, LLC Jeffersonville, Indiana | |
| Advanced Spine and Outpatient Surgery Center West Orange, New Jersey | |
| Advanced Spine and Pain North Valley Phoenix, Arizona | |
| Advanced Spine and Pain Specialists Spring, Texas | |
| Advanced Surg Ctr At Brownwood The Villages, Florida | |
| Advanced Surg Ctr of El Paso El Paso, Texas | |
| Advanced Surg Ctr of Northern Utah Logan, Utah | |
| Advanced Surgery Center Omaha, Nebraska | |
| Advanced Surgery Center Omaha, Nebraska | |
| Advanced Surgery Center of Coral Gables Coral Gables, Florida | |
| Advanced Surgery Center of Lancaster Lancaster, Pennsylvania | |
| Advanced Surgery Center of San Antonio, LLC San Antonio, Texas | |
| Advanced Surgery Center of Sarasota LLC Sarasota, Florida | |
| Advanced Surgical Care of Boerne Boerne, Texas | |
| Advanced Surgical Care of Clearwater Clearwater, Florida | |
| Advanced Surgical Care of Maryland Lanham, Maryland | |
| Advanced Surgical Center of Sunset Hills St Louis, Missouri | |
| Advanced Surgical Institute Sewell, New Jersey | |
| Advanced Surgl Care of Ocala Ocala, Florida | |
| Advancedcare Surg Ctr Ennis, Texas | |
| Advent Health Ottawa Ottawa, Kansas | |
| AdventHealth Central Texas Killeen, Texas | |
| AdventHealth GlenOaks Glendale Heights, Illinois | |
| AdventHealth Orlando Orlando, Florida | |
| AdventHealth Pain Medicine Orlando Orlando, Florida | |
| Adventhealth Heart Of Florida Davenport, Florida | |
| Adventhealth Sebring Sebring, Florida | |
| Adventist Bolingbrook Hospital Bolingbrook, Illinois | |
| Adventist Glenoaks Hospital Glendale Heights, Illinois | |
| Adventist Health St Helena St. Helena, California | |
| Adventist Hlthcr Surg Ctr At Natl Oxon Hill, Maryland | |
| Adventist Medical Glendale Glendale, California | |
| Advocate Christ Medical Center Oak Lawn, Illinois | |
| Advocate Condell Medical Center Libertyville, Illinois | |
| Advocate Good Shepard Hospital Barrington, Illinois | |
| Advocate Sherman Hospital Elgin, Illinois | |
| Aiken Regional Medical Center Aiken, South Carolina | |
| Ainsworth Surgery Center Garden City, New York | |
| Alabama Ortho Spine and Sports Birmingham, Alabama | |
| All City Family Healthcare Center Brooklyn, New York | |
| Allcity Family Hlthcr Ctr Brooklyn, New York | |
| Allegheny Surgery Center Altoona, Pennsylvania | |
| Allen County Hospital Iola, Kansas | |
| Allen Memorial Hosp Waterloo, Iowa | |
| Alliance Covington Covington, Georgia | |
| Alliance Specialty Surgery Center Ormond Beach, Florida | |
| Alliance Spine and Pain Peachtree City, Georgia | |
| Alliance Spine and Pain Ctrs Marietta, Georgia | |
| Alliance Spine and Pain Ctrs Marietta, Georgia | |
| Alliance Spine and Pain Ctrs Marietta, Georgia | |
| Alliance Spine and Pain Ctrs Marietta, Georgia | |
| Alliance Spine and Pain Ctrs Marietta, Georgia | |
| Alliance Spine and Pain Ctrs Marietta, Georgia | |
| Alliance Spine and Pain Ctrs Marietta, Georgia | |
| Alliance Spine and Pain Ctrs Marietta, Georgia | |
| Alliance Surg Ctr At Johns Creek Suwanee, Georgia | |
| Alliance Surgery Center, Inc Fullerton, California | |
| Allied Physicians Surg Ctr South Bend, Indiana | |
| Alpha Surgery Center Tomball, Texas | |
| Alton Memorial Hospital Alton, Illinois | |
| Altus Baytown Hospital Baytown, Texas | |
| Altus Houston Hospital Houston, Texas | |
| Altus Pasadena Surgical Center Pasadena, Texas | |
| Am Surg Ctr Colton, California | |
| Amb Pain and Disability Mgmt Ctr Jersey City, New Jersey | |
| Amb Surg Ctr of Stockton Stockton, California | |
| Ambulatory Surgery Center Tampa, Florida | |
| Ambulatory Surgery Center of Bala Cynwyd Bala-Cynwyd, Pennsylvania | |
| Ambulatory Surgery Center of Killeen Killeen, Texas | |
| Ambulatory Surgery Center of Spartanburg Spartanburg, South Carolina | |
| Ambulatory Surgical Center of New Jersey, LLC Edison, New Jersey | |
| Ambulatory Surgical Center of Somerset Bridgewater, New Jersey | |
| Ambulatory Surgical Institute of Dallas Addison, Texas | |
| Ambulatory Surgical Pavilion at Robert Wood Johnson New Brunswick, New Jersey | |
| Ambulatory Surgical Pavilion of New Jersey Hammonton, New Jersey | |
| Amc Cavazos - Pa Cavazos, Texas | |
| American Surgical Centers West Bloomfield, Michigan | |
| Ames Surgery Center Ames, Iowa | |
| Amherst Surgery Center Amherst, New York | |
| Anderson Hospital Maryville, Illinois | |
| Anderson Regional Health System Meridian, Mississippi | |
| Anderson Regional Medical Center Meridian, Mississippi | |
| Anderson Regional Medical Center, South Campus Meridian, Mississippi | |
| Anderson Surgery Center Edwardsville, Illinois | |
| Anesis Pain- Bel-Red ASC Bellevue, Washington | |
| Ann Arbor Surgl Ctr Ann Arbor, Michigan | |
| Anne Arundel Med Ctr Pavsadena Pasadena, Maryland | |
| Apex Pain and Wellness Foster City, California | |
| Apex Spine Institute ASC Richland, Washington | |
| Apex Surgery Center Ada, Oklahoma | |
| Apex Surgical Center Westmoreland, New York | |
| Apogee Outpatient Surgery Center Redding, California | |
| Apollo Surgery Center West Melbourne, Florida | |
| Apple Valley Outpatient Surgical Center Apple Valley, California | |
| Ardmore Regional Surgery Center Ardmore, Oklahoma | |
| Arizona Pain Specialists, LLC Tempe, Arizona | |
| Arizona Specialty Surgery Center Chandler, Arizona | |
| Arizona Surgical Specialists Center Tempe, Arizona | |
| Arizona Surgical Specialists Center Tempe, Arizona | |
| Arizona Surgl Spclsts Ctr Scottsdale, Arizona | |
| ArkLaMiss Surgery Center, LLC Monroe, Louisiana | |
| Arkansas Surg Hosp North Little Rock, Arkansas | |
| Armenia Ambulatory Surgery Center Tampa, Florida | |
| Armenia Ambulatory Surgery Center Tampa, Florida | |
| Arnot Ogden Hospital Elmira, New York | |
| Arrowhead North Surgery Center Peoria, Arizona | |
| Artesia General Hospital Artesia, New Mexico | |
| Asc of Boca Raton Boca Raton, Florida | |
| Ascension St John Hospital - Detroit Detroit, Michigan | |
| Ascension St. John Hospital Health Center at 23 Mile Macomb, Michigan | |
| Ascension Via Christi St. Francis Wichita, Kansas | |
| Ascent Surg Ctr Colorado Springs, Colorado | |
| Ascentist Leawood, Kansas | |
| Ashtabula County Medical Center Ashtabula, Ohio | |
| Aspen Surgery Center Simi Valley, California | |
| Aspire Rural Health System Marlette Marlette, Michigan | |
| Associated Surgical Center Arlington Heights, Illinois | |
| Associated Surgical Center of Dearborn Dearborn Heights, Michigan | |
| Athens Orthopedic Clinic (Loganville ASC) Loganville, Georgia | |
| Athens-Limestone Hospital Athens, Alabama | |
| Atlanta Ctr For Ent Atlanta, Georgia | |
| Atlanta Outpatient Surg Ctr Atlanta, Georgia | |
| Atlantic Coast Pain Specialists Conway, South Carolina | |
| Atlantic General Hospital Berlin, Maryland | |
| Atlantic Surgery Center West Islip, New York | |
| Atlantic Surgery Center West Islip, New York | |
| Atlas Surg Ctr Buffalo, New York | |
| Atrium Health Pineville Charlotte, North Carolina | |
| Atrium Medical Center Middletown, Ohio | |
| Auburn Community Hospital Auburn, New York | |
| Auburn Surgery Center Cape Girardeau, Missouri | |
| Audubon Surgery Center Colorado Springs, Colorado | |
| Augusta Health Fishersville, Virginia | |
| Augusta Pain Center Augusta, Georgia | |
| Augusta University Medical Center Augusta, Georgia | |
| Aultman Alliance Community Hospital Alliance, Ohio | |
| Aultman Health Foundation Canton, Ohio | |
| Aultman Orville Orrville, Ohio | |
| Aurora BayCare Medical Center Green Bay, Wisconsin | |
| Aurora Baycare Medical Center-Discovery Green Bay, Wisconsin | |
| Aurora Germantown Germantown, Wisconsin | |
| Aurora Health Care Southern Lakes, Inc Mount Pleasant, Wisconsin | |
| Aurora Health Care Southern Lakes, Inc. Waukesha, Wisconsin | |
| Aurora Health Care Southern Lakes, Inc.- Elkhorn Elkhorn, Wisconsin | |
| Aurora Health Center 84 South Greenfield, Wisconsin | |
| Aurora Health Center Southern Lakes Burlington, Wisconsin | |
| Aurora Health Fond Du Lac Fond du Lac, Wisconsin | |
| Aurora Med Ctr Wauwatosa, Wisconsin | |
| Aurora Medical Center Kenosha Kenosha, Wisconsin | |
| Aurora Medical Center Oshkosh Oshkosh, Wisconsin | |
| Aurora St Lukes Med Ctr Milwaukee, Wisconsin | |
| Aurora St Lukes Medical Center Milwaukee, Wisconsin | |
| Aurora St Lukes South Shore Cudahy, Wisconsin | |
| Aurora Surgery Centers LLC Greenfield, Wisconsin | |
| Austin Oral Surg Pflugerville, Texas | |
| Avalon Surgery and Robotic Center Glendale, California | |
| Aventura Hospital and Medical Center Aventura, Florida | |
| Avicenna Surgery Center The Bronx, New York | |
| B3 Medical Wesley Chapel, Florida | |
| Babcock Surgical Center San Antonio, Texas | |
| Bacon County Hospital Alma, Georgia | |
| Baldwin County Surg Ctr Fairhope, Alabama | |
| Banner - University Medical Center Tucson Tucson, Arizona | |
| Banner Enticare Tempe Surgery Center Tempe, Arizona | |
| Banner Health Surgicenter Phoenix, Arizona | |
| Banner Payson Medical Center Payson, Arizona | |
| Banner Sun City West Surgery Center, LLC Sun City West, Arizona | |
| Banner Surg Ctr Biltmore Phoenix, Arizona | |
| Banner Surg Ctr Desert Vista Scottsdale, Arizona | |
| Banner Surgery Center Tucson, Arizona | |
| Banner Surgery Center - Central Phoenix Phoenix, Arizona | |
| Banner Surgery Center - Desert Mesa, Arizona | |
| Banner Surgery Center - Mesa Mesa, Arizona | |
| Banner Surgery Center - Peoria Peoria, Arizona | |
| Banner University Medical Center South Tucson, Arizona | |
| Baptist Health Louisville Louisville, Kentucky | |
| Baptist Health Medical Center - Little Rock Little Rock, Arkansas | |
| Baptist Health Surgery Center, LLC Lexington, Kentucky | |
| Baptist Hospital of Miami Miami, Florida | |
| Baptist Med Ctr Yazoo Yazoo City, Mississippi | |
| Barclay Surg Ctr Rochester Hills, Michigan | |
| Barnes Jewish Hospital - North St Louis, Missouri | |
| Barnes Jewish Hospital South St Louis, Missouri | |
| Barnes Jewish N Hospital St Louis, Missouri | |
| Barnes-Jewish Hospital St Louis, Missouri | |
| Barnes-Jewish West County Hospital St Louis, Missouri | |
| Barnes-Jewish West County Hospital St Louis, Missouri | |
| Barrington Pain and Spine Institute LLC Barrington, Illinois | |
| Bass Surgery Center Walnut Creek, California | |
| Baxter Regional Medical Center Mountain Home, Arkansas | |
| Bayfront Health St. Petersburg St. Petersburg, Florida | |
| Bayfront Venice Reg Surgery Venice, Florida | |
| Baylor College of Medicine Med Ctr Houston, Texas | |
| Baylor Scott & White College Station Hospital College Station, Texas | |
| Baylor Scott & White Medical Center - Marble Falls Marble Falls, Texas | |
| Baylor Scott & White Medical Center Sunnyvale Sunnyvale, Texas | |
| Baylor Scott & White Surgical Hospital at Fort Worth Fort Worth, Texas | |
| Baylor Scott & White Surgicare North Dallas Dallas, Texas | |
| Baylor Scott & White Surgicare at Plano Alliance Plano, Texas | |
| Baylor Scott and White Med Ctr McKinney, Texas | |
| Baylor Scott and White Pain Clinic Temple, Texas | |
| Baylor Scott and White Surgicare Dallas, Texas | |
| Baylor Surgicare at Fort Worth Fort Worth, Texas | |
| Bayonne Medical Center Bayonne, New Jersey | |
| Bayshore Hospital Holmdel, New Jersey | |
| Baystate Medical Center Springfield, Massachusetts | |
| Baystate Medical Center - Holyoke Holyoke, Massachusetts | |
| Baystate Pain Management Center Springfield, Massachusetts | |
| Baytown Hospital Baytown, Texas | |
| Baytown Medical Center Baytown, Texas | |
| Bayview Surgery Center Sarasota, Florida | |
| Beach Cities Orthopedic Surgery Center Manhattan Beach, California | |
| Beachwood Medical Center Beachwood, Ohio | |
| Beacon Surgery Center Lee's Summit, Missouri | |
| Beacon West Surg Ctr Leawood, Kansas | |
| Bear Creek Surg Ctr Keller, Texas | |
| Belleair Surgery Center Ltd Clearwater, Florida | |
| Bellevue Medical Center Bellevue, Nebraska | |
| Bellevue Surgery Center Bellevue, Washington | |
| Bellin Memorial Hospital Green Bay, Wisconsin | |
| Belpre Distribution Ctr Belpre, Ohio | |
| Beltway Surg Ctr Indianapolis, Indiana | |
| Bend Surgery Center Bend, Oregon | |
| Berkshire Medical Center Pittsfield, Massachusetts | |
| Berlin Interventional Pain Management Berlin, Maryland | |
| Beth Ambulatory Surgery Center Boynton Beach, Florida | |
| Beth Israel Deaconess - Plymouth Plymouth, Massachusetts | |
| Beth Israel Deaconess Hospital Needham, Massachusetts | |
| Beth Israel Deaconess Medical Center Boston, Massachusetts | |
| Bethel Park Surgery Center Bethel Park, Pennsylvania | |
| Bethesda North Hospital Cincinnati, Ohio | |
| Bethesda Orthopedic Surgery Center Cincinnati, Ohio | |
| Bethesda Outpatient Surgery Center West Palm Beach, Florida | |
| Bingham Memorial Hospital Blackfoot, Idaho | |
| Biohealth Surgl Instu Santa Monica, California | |
| Birmingham Surgery Center Birmingham, Alabama | |
| Black Hills Surgical Hospital Rapid City, South Dakota | |
| Bloomfield Hills Surgical Center Bloomfield Hills, Michigan | |
| Bloomfield Surgi-Center Bloomfield, New Jersey | |
| Blount Mem Hosp Maryville, Tennessee | |
| Blue Ridge Surgery Center Salem, Virginia | |
| Blue Ridge Surgery Center Salem, Virginia | |
| Blue Water Surgery Center Port Huron, Michigan | |
| Blue Water Surgery Center FL Port Saint Lucie, Florida | |
| Bluffton Okatie Outpatient Center Okatie, South Carolina | |
| Boca Raton Regional Boca Raton, Florida | |
| Boca Raton Surgery Center Boca Raton, Florida | |
| Body Balance Chiropractic and Wellness Houston, Texas | |
| Bone & Joint Surgical Suites Sebring, Florida | |
| Boynton Beach Ambulatory Surgery Center Boynton Beach, Florida | |
| Bozeman Outpatient Surgery Center Bozeman, Montana | |
| Bradenton Surgery Center Dublin, Ohio | |
| Brandon Ambulatory Surgery Center Brandon, Florida | |
| Brandon Surg Ctr Brandon, Florida | |
| Brandywine Hospital Coatesville, Pennsylvania | |
| Brecksville Surgery Brecksville, Ohio | |
| Briarcliff Surgery Center Kansas City, Missouri | |
| Bridgewater Ambulatory Surgery Center Bridgewater, New Jersey | |
| Brigham & Womens Hospital Boston, Massachusetts | |
| Brigham and Women's Faulkner Hospital Boston, Massachusetts | |
| Brigham and Women's Foxborough Foxborough, Massachusetts | |
| Brigham and Women's Hospital Boston, Massachusetts | |
| Brigham and Women's-Mass General Health Care Center Foxborough, Massachusetts | |
| Bristol Regional Medical Center Bristol, Tennessee | |
| Broadwest Specialty Surgical Center, LLC Merrillville, Indiana | |
| Brodstone Memorial Hospital Superior, Nebraska | |
| Brooke Army Medical Center Fort Sam Houston, Texas | |
| Brookings Ambulatory Surgery Center Brookings, South Dakota | |
| Brooklyn Surgery Center Brooklyn, New York | |
| Brooklyn VA Medical Center Brooklyn, New York | |
| Broward Specialty Surgical Center Hollywood, Florida | |
| Brunswick Pain Treatment Center Brunswick, Georgia | |
| Brunswick Surgery Center Leland, North Carolina | |
| Bryn Mawr Orthopedic Surgery Center Bryn Mawr, Pennsylvania | |
| Bucks County Surgical Suites Warrington, Pennsylvania | |
| Bucks County Surgl Suites Highpoint Chalfont, Pennsylvania | |
| Bucyrus Hospital Bucyrus, Ohio | |
| Bullhead City Community Hosp Bullhead City, Arizona | |
| Burbank Spine and Pain Surgery Center Burbank, California | |
| Burke Health Pain Management Waynesboro, Georgia | |
| Burlington Asc Hainesport, New Jersey | |
| Burnside Surgery Center Gresham, Oregon | |
| Butler County Health Care Center David City, Nebraska | |
| Bux Pain Management Lexington, Kentucky | |
| CGH Medical Center Sterling, Illinois | |
| CHI Health St. Francis Grand Island, Nebraska | |
| CHI St. Joseph Health Outpatient Surgery Center Lexington, Kentucky | |
| CHRISTUS Good Shepherd Medical Center - Longview Longview, Texas | |
| CHRISTUS Southeast Texas -St. Elizabeth Beaumont, Texas | |
| CVVCA Business, LLC Pine Bluff, Arkansas | |
| Cabell Huntington Hospital Huntington, West Virginia | |
| Cache Valley Surg Ctr Logan, Utah | |
| Calabasas Surgery Center Calabasas, California | |
| Calais Regional Hospital Calais, Maine | |
| California Pacific Med Ctr Mission San Francisco, California | |
| California Specialty Surgery Center Mission Viejo, California | |
| Camden Clark Medical Center Parkersburg, West Virginia | |
| Camis, Llc Eatontown, New Jersey | |
| Cancer Treatment Ctrs of America At Newnan, Georgia | |
| Canyon Surgl Ctr Mesa, Arizona | |
| Cape Coral Surg Ctr Cape Coral, Florida | |
| Cape Regional Medical Center Cape May Court House, New Jersey | |
| Capital City Surgery Center Raleigh, North Carolina | |
| Capital Health Med Ctr Hopewell Pennington, New Jersey | |
| Capital Spine and Pain Ctrs Reston, Virginia | |
| Capital Surgical Ctr Baton Rouge, Louisiana | |
| Capitol Pain Institute Austin, Texas | |
| Capitol Pain Instu Louisville, Kentucky | |
| Capitol Street Surgery Center Indianapolis, Indiana | |
| Capitol Surgical Center Bethesda, Maryland | |
| Carepath Injury Ctr of Pennsylvania Allentown, Pennsylvania | |
| Carl R Darnall Army Med Ctr Fort Cavazos, Texas | |
| Carle BroMenn Medical Center Normal, Illinois | |
| Carle Champaign Surgicenter Champaign, Illinois | |
| Carle Foundation Hosp Urbana, Illinois | |
| Carle Foundation Hosp Urbana, Illinois | |
| Carle Foundation Hospital Urbana, Illinois | |
| Carlsbad Surgery Center Carlsbad, California | |
| CaroMont Regional Medical Center Gastonia, North Carolina | |
| CarolinaEast Medical Center New Bern, North Carolina | |
| Caromount Partners Llc Dba Belmont, North Carolina | |
| Carris Health Rice Mem Hosp Willmar, Minnesota | |
| Carroll County Memorial Hospital Carrollton, Missouri | |
| Carrollton Reg Med Ctr Carrollton, Texas | |
| Carson Tahoe Regional Healthcare Carson City, Nevada | |
| Carson Tahoe Regional Medical Center Carson City, Nevada | |
| Carteret General Hospital Morehead City, North Carolina | |
| Cascade Spine Center Tualatin, Oregon | |
| Castle Hills Surgicare Carrollton, Texas | |
| Castle Surg Ctr Southlake, Texas | |
| Castleview Hospital Price, Utah | |
| Cataract Center of East Texas Tyler, Texas | |
| Catholic Medical Center Manchester, New Hampshire | |
| Catskill Regional Medical Center Harris, New York | |
| Cayuga Medical Center at Ithaca Ithaca, New York | |
| Cedar Crest Surg Ctr Allentown, Pennsylvania | |
| Cedar Park Surgery Center Cedar Park, Texas | |
| Centegra Hosp McHenry McHenry, Illinois | |
| Centeno-Schultz Clinic Broomfield, Colorado | |
| Center For Minimally Invasive Surgery Mokena, Illinois | |
| Center for Advanced Surgery Ladson, South Carolina | |
| Center for Pain Management Ambulatory Surgery Center-Sartell Sartell, Minnesota | |
| Center for Pain Management Ambulatory Surgery, LLC Alexandria, Minnesota | |
| Center for Pain Medicine and Surgery Center Fargo, North Dakota | |
| Center for Southside Surgery, LLC Greenwood, Indiana | |
| Center for Special Surgery Indianapolis, Indiana | |
| Center for Specialized Surgery LP Bethlehem, Pennsylvania | |
| Center for Specialty Surgery of Austin Austin, Texas | |
| Center for Spine Interventions ASC, LLC (ASC3) Acworth, Georgia | |
| Center for Sports Medicine and Orthopaedics Ambulatory Surgery Center Chattanooga, Tennessee | |
| Centers For Pain Solutions Nashua, New Hampshire | |
| CentraCare - Willmar Surgery Center Willmar, Minnesota | |
| CentraCare Health Monticello Monticello, Minnesota | |
| CentraCare Plaza Saint Cloud, Minnesota | |
| Central Arkansas Surgery Center Little Rock, Arkansas | |
| Central Arkansas Vetrns Hlthcr Syst Little Rock, Arkansas | |
| Central Baptist Hospital Lexington, Kentucky | |
| Central Coast Surg Ctr Freedom, California | |
| Central Florida Endoscopy and Surgical Institute of Ocala Ocala, Florida | |
| Central Florida Spine & Pain Melbourne, Florida | |
| Central Jersey Surgery Center, LLC Eatontown, New Jersey | |
| Central Kentucky Surgery Center Danville, Kentucky | |
| Central Oregon Surgical Institute Bend, Oregon | |
| Central Texas Day Surgery Center Killeen, Texas | |
| Central Valley Surg Ctr Santa Barbara, California | |
| Centrum Surgical Center Greenwood, Colorado | |
| Centurion Surgery Center of Jacksonville Jacksonville, Florida | |
| Chandler Surgical Ctr PLC Chandler, Arizona | |
| Charles Regional Surgery Center La Plata, Maryland | |
| Charleston Area Med Ctr Teays Hurricane, West Virginia | |
| Charlie Norwood Va Med Ctr Augusta, Georgia | |
| Charlotte Surgery Center Charlotte, North Carolina | |
| Chase Gardens Surgery Center Eugene, Oregon | |
| Chattanooga Pain Surgery Center Hixson, Tennessee | |
| Chesapeake Urology Holy Cross Germantown, Maryland | |
| Chestnut Hill Hospital Philadelphia, Pennsylvania | |
| Chi St Lukes Health Patience Med Pasadena, Texas | |
| Chico Surgery Center Chico, California | |
| Chilton Mem Hosp Pompton Plains, New Jersey | |
| Chippenham Hospital Richmond, Virginia | |
| Christian Hospital St Louis, Missouri | |
| Christiana Surgicenter Newark, Delaware | |
| Christus Mother Frances Hospital Sulphur Springs, Texas | |
| Christus Physicians Ambulatory Surgery Center New Braunfels, Texas | |
| Christus Santa Rosa Hosp Westover San Antonio, Texas | |
| Christus St Michael Health System Texarkana, Texas | |
| Christus Surgery Center at Olympia Hills Universal City, Texas | |
| Citizens Medical Center Victoria, Texas | |
| Citizens Memorial Hospital Bolivar, Missouri | |
| Clark Regional Medical Center Winchester, Kentucky | |
| Clay Surgery Center Orange Park, Florida | |
| Clear Creek Surgery Center Wheat Ridge, Colorado | |
| Clearview Eye Surgery Center Vincennes, Indiana | |
| Clearway Pain Solutions Waldorf, Maryland | |
| Clearway Pain Solutions Waldorf, Maryland | |
| Clearway Pain Solutions Waldorf, Maryland | |
| Clearway Pain Solutions Waldorf, Maryland | |
| Clearway Pain Solutions Waldorf, Maryland | |
| Clearway Pain Solutions Waldorf, Maryland | |
| Clearway Pain Solutions Waldorf, Maryland | |
| Clearway Pain Solutions Waldorf, Maryland | |
| Clearway Pain Solutions Waldorf, Maryland | |
| Clearway Pain Solutions Waldorf, Maryland | |
| Clearway Pain Solutions Waldorf, Maryland | |
| Clearway Pain Solutions - Bel Air Bel Air, Maryland | |
| Clearway Pain Solutions - Bethesda Bethesda, Maryland | |
| Clearway Pain Solutions - Columbia Columbia, Maryland | |
| Clearway Pain Solutions - Easton Easton, Maryland | |
| Clearway Pain Solutions - Salisbury Salisbury, Maryland | |
| Clearway Pain Solutions - Westminster Westminster, Maryland | |
| Clearway Pain Solutions - White Marsh Nottingham, Maryland | |
| Clearway Pain Solutions Largo Upper Marlboro, Maryland | |
| Clearway Surgery Center - Prince Frederick Prince Frederick, Maryland | |
| Clearway Surgery Center - WALDORF ASC Waldorf, Maryland | |
| Cleveland Clinic - Avon Hospital Avon, Ohio | |
| Cleveland Clinic - Pain Management Cleveland, Ohio | |
| Cleveland Clinic - Twinsburg Family Health & Surgery Center Twinsburg, Ohio | |
| Cleveland Clinic of Weston Weston, Florida | |
| Clifton Springs Hospital & Clinic Clifton Springs, New York | |
| Clifton Surgery Center, Inc Clifton, New Jersey | |
| Cmps Surg Ctr Daly City, California | |
| Coast Surgery Center of South Bay Torrance, California | |
| Coastal A.S.C, LLC Carlsbad, California | |
| Coastal Carolina Hospital Hardeeville, South Carolina | |
| Coastal Surgery Center Santa Barbara, California | |
| Coastal Surgery Center Santa Barbara, California | |
| Colonial Outpatient Surgery Center LLC Fort Myers, Florida | |
| Colorado Premier Surgery Center at Greenwood Village Greenwood Village, Colorado | |
| Columbia Pain Management, PC Milwaukie, Oregon | |
| Columbus Community Hosp Columbus, Texas | |
| Colusa Med Ctr Colusa, California | |
| Community Medical Center Scranton, Pennsylvania | |
| Community Surgery Center East Indianapolis, Indiana | |
| Complete Spine and Pain Care Framingham, Massachusetts | |
| Complete Surgery Center Northwest Houston, Texas | |
| Comprehensive Pain Management Center Fresno, California | |
| Comprehensive Pain Management Center- St Charles Surgical Center Thousand Oaks, California | |
| Concourse Diagnostic & Surgical Center City of Industry, California | |
| Connecticut Surgery Center Farmington, Connecticut | |
| Conway Ambulatory Surgery Center Conway, Arkansas | |
| Cookeville Regional Medical Center (N Washington Ave) Cookeville, Tennessee | |
| Cool Springs Surgery Center LLC Franklin, Tennessee | |
| Copper Basin Surg Ctr Wasilla, Alaska | |
| Copper Ridge Surgery Center Traverse City, Michigan | |
| Coral Desert Surgery Center LLC St. George, Utah | |
| Coral Gables Hospital Miami, Florida | |
| Coral Gables Surgery Center Miami, Florida | |
| Coral Ridge Outpatient Center Oakland Park, Florida | |
| Corewell Health William Beaumont University Hospital Royal Oak, Michigan | |
| Cornell Surgery Center Beaverton, Oregon | |
| Coronado Surgery Center Sierra Vista, Arizona | |
| Coryell Health Gatesville, Texas | |
| Court Street Surgery Center Redding, California | |
| Courtyard Surgery Pavilion Visalia, California | |
| Crater Lake Surgery Center Medford, Oregon | |
| Crossings Surgery Center Warwick, Rhode Island | |
| Crossroads Surgery Center Brentwood, Tennessee | |
| Crystal Outpatient Surgery Center Houston, Texas | |
| Crystal Run Healthcare ASC Middletown, New York | |
| Ctr For Advanced Surgical Spclsts Tampa, Florida | |
| Ctr For Ortho Surg Van Nuys, California | |
| Ctr For Pain Mgmt Bemidji, Minnesota | |
| Ctr For Spine Interventions Dallas, Georgia | |
| Ctr For the Surgl Arts Altoona, Pennsylvania | |
| Ctr for Spine and Pain Medicine Dalton, Georgia | |
| Cushing Memorial Hospital Leavenworth, Kansas | |
| Cypress Ambulatory Surgery Center Santa Maria, California | |
| Cypress Creek Outpatient Surgical Center Fort Lauderdale, Florida | |
| DCR Surgery Center Centerville, Ohio | |
| DLJT Management Services, LLC Las Vegas, Nevada | |
| DLP Rutherford Regional Health System Rutherfordton, North Carolina | |
| Dallas County Hospital Perry, Iowa | |
| Dallas Medical Center Dallas, Texas | |
| Dameron Hospital Stockton, California | |
| Davenport Ambulatory Surgery Center Davenport, Florida | |
| David Grant USAF Medical Center Travis Air Force Base, California | |
| Davis Medical Center Elkins, West Virginia | |
| Day Op Center of Long Island Mineola, New York | |
| Day Op Ctr of Long Island Woodbury, New York | |
| Day Surg Ctr Winter Haven, Florida | |
| Day Surgery Center Charleston, West Virginia | |
| Dcr Surgery Center, Llc Centerville, Ohio | |
| De Witt Cmnty Hosp De Witt, Iowa | |
| DeTar Hospital North Victoria, Texas | |
| Deaconess Gateway Newburgh, Indiana | |
| Deaconess Henderson Hospital Henderson, Kentucky | |
| Deaconess Main Evansville, Indiana | |
| Dearborn Surgery Center Dearborn, Michigan | |
| Deca Health Toledo, Ohio | |
| Decatur Ambulatory Surgery Center Decatur, Alabama | |
| Deer Creek Surgery Center Chico, California | |
| Deer River Hlthcare Ctr Deer River, Minnesota | |
| Delaware Outpatient Center for Surgery Newark, Delaware | |
| Delmarva Pain Newark, New York | |
| Delray Beach Surgery center Delray Beach, Florida | |
| Delray Beach Surgical Suites Delray Beach, Florida | |
| Delta Bay Surgery Center, LLC Benicia, California | |
| Deschutes Surgery Center Bend, Oregon | |
| Desert Valley Hospital Victorville, California | |
| Detroit Receiving Hospital Detroit, Michigan | |
| District Surg Ctr Bethesda, Maryland | |
| Doctors Hospital Columbus, Ohio | |
| Doctors Hospital Columbus, Ohio | |
| Doctors Hospital of Laredo Laredo, Texas | |
| Doctors Medical Center Modesto Modesto, California | |
| Doctors Outpatient Center for Surgery: DOCS Los Angeles, California | |
| Doctors Outpatient Surgery Center Lincoln, Nebraska | |
| Doctors Outpatient Surgery Center, LLC Lafayette, Louisiana | |
| Doctors United Surgery Center Pasadena, Texas | |
| Door County Memorial Hospital Sturgeon Bay, Wisconsin | |
| Downtown Surgery Center Orlando, Florida | |
| Drexel Town Square Surg Ctr Menomonee Falls, Wisconsin | |
| Drs Same Day Surg Ctr Marrero, Louisiana | |
| Dry Creek Surgery Center Englewood, Colorado | |
| Dublin Surgery Center Dublin, Ohio | |
| Duly Surg Ctr Lombard Lombard, Illinois | |
| Duncan Regional Hospital Duncan, Oklahoma | |
| ECMC Hospital Buffalo, New York | |
| ECU Health Beaufort Hospital Washington, North Carolina | |
| EPC Surgery Center La Mesa, California | |
| Eagle Highlands Surgery Center Indianapolis, Indiana | |
| East Brunswick Surgery Center East Brunswick, New Jersey | |
| East Coast Surgery Center Daytona Beach, Florida | |
| East Cooper Medical Center Mt. Pleasant, South Carolina | |
| East Houston Medical Center Houston, Texas | |
| East Orange Gen Hosp East Orange, New Jersey | |
| East Portland Surgery Center Portland, Oregon | |
| Eastern Long Island Hospital Greenport, New York | |
| Eastern Oklahoma Va Health Care Muskogee, Oklahoma | |
| Eastwind Surgical LLC Westerville, Ohio | |
| Eaton Rapids Med Ctr Eaton Rapids, Michigan | |
| Edgar County Hospital Paris, Illinois | |
| Edgerton Hospital and Health Services Edgerton, Wisconsin | |
| Edgewood Surgical Hospital Transfer, Pennsylvania | |
| Edison Surgery Center, LLC Edison, New Jersey | |
| Edward Hospital Naperville, Illinois | |
| Edwardsville Ambulatory Surgery Center LLC Glen Carbon, Illinois | |
| Effingham Amb Surg Ctr Effingham, Illinois | |
| Einstein Medical Center Montgomery East Norriton, Pennsylvania | |
| El Paso Center for GI El Paso, Texas | |
| El Paso Specialty Hospital El Paso, Texas | |
| Elkridge Ambulatory Surgery Center Elkridge, Maryland | |
| Ellenville Regional Hospital Ellenville, New York | |
| Ellicott City Ambulatory Surgery Center Ellicott City, Maryland | |
| Elliot Hospital Manchester, New Hampshire | |
| Embassy Surgery Center Lancaster, California | |
| EmergeOrtho-Smithfield Smithfield, North Carolina | |
| Emory Decatur Hosp Decatur, Georgia | |
| Emory Johns Creek Johns Creek, Georgia | |
| Emory University Hospital Atlanta, Georgia | |
| Empire State Ambulatory Surgical Center The Bronx, New York | |
| Encore Surg Ctr Covina, California | |
| Englewood Cliffs Surg Ctr Englewood Cliffs, New Jersey | |
| Englewood Surgery Center Englewood, Colorado | |
| Enhance Center for Interventional Spine and Sports Livonia, Michigan | |
| Enloe Medical Center Chico, California | |
| Ephraim McDowell James B Haggin Hospital Hardinsburg, Kentucky | |
| Ephraim McDowell Regional Medical Center Danville, Kentucky | |
| Erie Shores Surg Ctr Sandusky, Ohio | |
| Essentia Health - Duluth Duluth, Minnesota | |
| Evans Procedure Center,LLC Evans, Georgia | |
| Evanston Hospital Northshore University Health System Evanston, Illinois | |
| Evanston Regional Hospital Evanston, Wyoming | |
| Everett Road Surgery Center Albany, New York | |
| Evolve Restorative Center Petaluma, California | |
| Executive Ambulatory Surgical Center Dearborn, Michigan | |
| Executive Surg Ctr of Little Rock Little Rock, Arkansas | |
| Executive Surgery Center Tomball, Texas | |
| F.F. Thompson Hospital Canandaigua, New York | |
| FHN Memorial Hospital Freeport, Illinois | |
| FSA of Huntingdon Valley, LLC Huntingdon Valley, Pennsylvania | |
| Fairbanks Memorial Hospital Fairbanks, Alaska | |
| Fairfax Surgical Ctr Fairfax, Virginia | |
| Fairfield Hospital Fairfield, Ohio | |
| Fairfield Surgery Center Fairfield, Connecticut | |
| Fairview UMN Health Minneapolis, Minnesota | |
| Faith Regional Health Services Norfolk, Nebraska | |
| Faith Regional Surgery Center Norfolk, Nebraska | |
| Falconhead Surgery Center Austin, Texas | |
| Family Health West Hospital Fruita, Colorado | |
| Fellowship Surgery Center Mount Laurel, New Jersey | |
| Fifth Avenue Surgery Center New York, New York | |
| First Choice Asc San Antonio, Texas | |
| First Coast Surgery Center Jacksonville, Florida | |
| FirstHealth Moore Regional Hospital Pinehurst, North Carolina | |
| Fisher-Titus Medical Center Norwalk, Ohio | |
| Fishkill Ambulatory Surgery Center Fishkill, New York | |
| Fitzgibbon Memorial Hospital Marshall, Missouri | |
| Flaget Memorial Hospital Bardstown, Kentucky | |
| Flagler Surgery Center Saint Augustine, Florida | |
| Fletcher Allen Hlthcr Williston, Vermont | |
| Florida Hospital Zephyrhills Zephyrhills, Florida | |
| Florida Pain Management Associates, PA Sebastian, Florida | |
| Florida Physical Medicine St. Petersburg, Florida | |
| Florida Specialty Surgery Center St. Petersburg, Florida | |
| Flowood Surgery Center, LLC Flowood, Mississippi | |
| Folsom Surgery Center Folsom, California | |
| Foothill Reg Med Ctr Tustin, California | |
| Forbes Hosp Monroeville, Pennsylvania | |
| Forest Health Medical Center Ypsilanti, Michigan | |
| Forest Health Medical Center of Bucks County Langhorne, Pennsylvania | |
| Fort Hamilton Hospital Hamilton, Ohio | |
| Fort Lauderdale Heart and Rhythm Fort Lauderdale, Florida | |
| Fort Lauderdale Pain Medicine Fort Lauderdale, Florida | |
| Fort Sutter Surgery Center Sacramento, California | |
| Foundation Hospital San Antonio, Texas | |
| Fountain Point Surgery Center Norfolk, Nebraska | |
| Franciscan Health Dyer Dyer, Indiana | |
| Franciscan Health Michigan City Michigan City, Indiana | |
| Franciscan St Francis Health Indianapolis, Indiana | |
| Frank R Howard Mem Hosp Willits, California | |
| Frankfort Regional Medical Center Frankfort, Kentucky | |
| Franklin County Hosp Preston, Idaho | |
| Franklin Memorial Hospital Farmington, Maine | |
| Freedom Surgical Center, LLC Bloomfield, New Jersey | |
| Freeman Health System Joplin, Missouri | |
| Fresno Surgical Hospital Fresno, California | |
| Froedtert Integrated Svc Menomonee Falls, Wisconsin | |
| Frontenac Surgery and Spine Center Frontenac, Missouri | |
| Fullerton Kimble Med Ctr Chicago, Illinois | |
| GA Interventional Pain, LLC Lawrenceville, Georgia | |
| GA Interventional Pain- F, LLC Roswell, Georgia | |
| GA Interventional Pain-B, LLC Braselton, Georgia | |
| GA Interventional Pain-C, LLC Cumming, Georgia | |
| GA Interventional Pain-D, LLC Decatur, Georgia | |
| GA Interventional Pain-E, LLC Canton, Georgia | |
| GA Interventional Pain-G, LLC Dalton, Georgia | |
| GA Interventional Pain-H, LLC Carrollton, Georgia | |
| GA Interventional Pain-I, LLC Rome, Georgia | |
| GA Interventional Pain-J, LLC Stockbridge, Georgia | |
| GA Interventional Pain-K, LLC Conyers, Georgia | |
| GA Interventional Pain-L, LLC Athens, Georgia | |
| Gabay and Gottlief Cosmetic Surg Ct Philadelphia, Pennsylvania | |
| Galileo Surgery Center San Luis Obispo, California | |
| Galion Community Hospital Galion, Ohio | |
| Gamma Surgery Center Pittsburgh, Pennsylvania | |
| Gardendale Surgical Center Gardendale, Alabama | |
| Gateway Surgical Center El Paso, Texas | |
| Geisinger Med Ctr Muncy Muncy, Pennsylvania | |
| Gemini Surgery Center Columbus, Ohio | |
| Genesis Hosp Zanesville, Ohio | |
| Genesis Medical Center Davenport, Iowa | |
| Genesis Surgery Center Lansing, Michigan | |
| Genesys Surgery Center LLC Westland, Michigan | |
| Geneva Surgical Suites LLC Genoa City, Wisconsin | |
| George Washington Univ Hosp Washington D.C., District of Columbia | |
| Georgia Pain and Spine Care Newnan, Georgia | |
| Gibson Area Hosp and Health Svcs Gibson City, Illinois | |
| Gibson General Hospital Princeton, Indiana | |
| Gila Valley Procedure Center Safford, Arizona | |
| Gladiolus Surgery Center LLC Fort Myers, Florida | |
| Glasgow Surgery Center Newark, Delaware | |
| Glatz Group McAllen, Texas | |
| Glen Rose Med Ctr Glen Rose, Texas | |
| Glenwood Surge Ctr Riverside, California | |
| Global Microsurgical Ctr of Park Park City, Utah | |
| Global Surgery Center Oradell, New Jersey | |
| GoldStep Ambulatory Surgery Center, LLC Brooklyn, New York | |
| Golden Ridge Surgery Center Golden, Colorado | |
| Golden Springs Surgical Center Cathedral City, California | |
| Golf Surgical Center Des Plaines, Illinois | |
| Good Samaritan Hospital Corvallis, Oregon | |
| Good Samaritan Hospital Corvallis, Oregon | |
| Good Shepherd Medical Center Hermiston, Oregon | |
| Goshen Surg Ctr Goshen, Indiana | |
| Grace Medical Center Lubbock, Texas | |
| Grace Medical Center - OP Lubbock, Texas | |
| Grady Health System Atlanta, Georgia | |
| Grady Memorial Hosp Chickasha, Oklahoma | |
| Gramercy Surgery Center Flushing, New York | |
| Granbury Hosp Corp Granbury, Texas | |
| Grand Island Regional Medical Center Grand Island, Nebraska | |
| Grand Island Surgery Center Grand Island, Nebraska | |
| Grand Rapids Surgical Suites Grand Rapids, Michigan | |
| Grand Valley Surgical Center Grand Rapids, Michigan | |
| Grand View Surgery Center at Harleysville Harleysville, Pennsylvania | |
| Granville Medical Center Oxford, North Carolina | |
| Great Lakes Pain Management Willoughby Hills, Ohio | |
| Great Lakes Surgical Center Southfield, Michigan | |
| Great Plains Regional Medical Center Elk City, Oklahoma | |
| Greater Erie Surgery Center Erie, Pennsylvania | |
| Greater Erie Surgery Center, LLC Erie, Pennsylvania | |
| Greensboro Specialty Surgical Center Greensboro, North Carolina | |
| Greenview Surg Ctr Bowling Green, Kentucky | |
| Greenwich Village Ambulatory Surgery Center New York, New York | |
| Griffin Ctr For Pain and Spine Griffin, Georgia | |
| Grove Place Surgery Center Vero Beach, Florida | |
| Gulf Pointe Surgery Center Port Charlotte, Florida | |
| Gwinnett Med Ctr Lawrenceville, Georgia | |
| HHC Southington Surgery Center, LLC, DBA Cheshire Surgery Center Cheshire, Connecticut | |
| Habana Ambulatory Surgery Center Tampa, Florida | |
| Hackensack Musculoskeletal Surg Ctr Hackensack, New Jersey | |
| Hackensack Surgery Center, LLC Hackensack, New Jersey | |
| Halifax Regional Medical Center, Inc. Roanoke Rapids, North Carolina | |
| Hallandale Outpatient Surgical Center Hallandale, Florida | |
| Hamilton Amb Surg Ctr Dalton, Georgia | |
| Hamilton Gen Hosp Hamilton, Texas | |
| Hamilton Surgery Center Hamilton, New Jersey | |
| Hanover Hills Surgery Center LLC Florham Park, New Jersey | |
| Hanover Parkway Surgery Center Greenbelt, Maryland | |
| Harbor Heights Surg Ctr Oxon Hill, Maryland | |
| Harborside Surg Ctr Oxon Hill, Maryland | |
| Harmony Surgery Center Fort Collins, Colorado | |
| Harrison County Community Hospital Bethany, Missouri | |
| Harrison Endo Surgical Center Harrison, New Jersey | |
| Harrison Memorial Hospital Cynthiana, Kentucky | |
| Hartford Hospital Hartford, Connecticut | |
| Hattiesburg Clinic Hattiesburg, Mississippi | |
| Hauppauge SC Hauppauge, New York | |
| Havasu Surgery Center Lake Havasu City, Arizona | |
| Hawthorn Surgery Center Vernon Hills, Illinois | |
| Hayden Surgical Center Scottsdale, Arizona | |
| Haymarket Surgery Center Haymarket, Virginia | |
| Hays Med Ctr Hays, Kansas | |
| Hays Surgery Center Kyle, Texas | |
| Hca Houston Hlthcr Northwest Houston, Texas | |
| Headache and Pain Ctr New Iberia, Louisiana | |
| Healdsburg District Hospital Healdsburg, California | |
| Health East ASC Englewood, New Jersey | |
| Healthsouth Sunrise Rehab Hospital Sunrise, Florida | |
| Heart of America Surgery Kansas City, Kansas | |
| Heartland Radiology Grand Island, Nebraska | |
| Hedrick Medical Center Chillicothe, Missouri | |
| Heights Surgical Institute Newport Beach, California | |
| Helena Surgicenter Helena, Montana | |
| Hemlock Ambulatory Surgery Center Macon, Georgia | |
| Hendrick Med Ctr South Abilene, Texas | |
| Henrico Doctors Hospital Richmond, Virginia | |
| Henry Ford Health System - Columbus Novi, Michigan | |
| Henry Ford Health System - Dearborn Dearborn, Michigan | |
| Henry Ford Health System - Royal Oak Royal Oak, Michigan | |
| Henry Ford Health System- Plymouth Plymouth, Michigan | |
| Heritage One Day Surgery North Syracuse, New York | |
| Herndon Surgery Center Fresno, California | |
| Herrin Hospital Herrin, Illinois | |
| Hershey Outpatient Surgery Center Hershey, Pennsylvania | |
| Highland District Hospital Hillsboro, Ohio | |
| Highland Medical Center Scottsboro, Alabama | |
| Highland Park Hospital Northshore University Health System Highland Park, Illinois | |
| Highline South Ambulatory Surgery Center, LLC Littleton, Colorado | |
| Hillcrest Hospital Mayfield Heights, Ohio | |
| Hinsdale Surgical Center Hinsdale, Illinois | |
| Hoboken Univ Med Ctr Hoboken, New Jersey | |
| Hocking Valley Community Hospital Logan, Ohio | |
| Hollywood Regional Surgery Center Hollywood, Florida | |
| Holy Cross Hosp Jordan Valley West West Valley City, Utah | |
| Holy Cross Hosp Pain Mgmt Oakland Park, Florida | |
| Holy Cross Hospital Fort Lauderdale, Florida | |
| Holy Cross Hospital, FTL Fort Lauderdale, Florida | |
| Holy Name Medical Center Teaneck, New Jersey | |
| Holyoke Medical Center Inc Holyoke, Massachusetts | |
| Holzer Gallipolis Gallipolis, Ohio | |
| Hope Ambulatory Surgery Center Irvine, California | |
| Horizon Health Paris, Illinois | |
| Horizon Medical Center Dallas, Texas | |
| Houston Meth Cypress Hosp Cypress, Texas | |
| Houston Methodist Baytown Hospital Baytown, Texas | |
| Houston Methodist Clear Lake Hospital Nassau Bay, Texas | |
| Houston Methodist Orthopedic & Sports Medicine Houston, Texas | |
| Houston Methodist Sugar Land Hospital Sugar Land, Texas | |
| Houston Methodist Surgery Center Baytown, Texas | |
| Houston Methodist The Woodlands Hospital The Woodlands, Texas | |
| Houston Methodist Willowbrook Hospital Houston, Texas | |
| Houston Orthopedic and Spine Surgery Center Katy, Texas | |
| Houston Physicians Hospital Webster, Texas | |
| Houston Premier Surgery Center in The Villages Houston, Texas | |
| Houston Surgery Center Houston, Texas | |
| Howard County Medical Center Saint Paul, Nebraska | |
| Hoyman Hong San Mateo, California | |
| Hudson Crossing Surgery Center Fort Lee, New Jersey | |
| Hudson Medical Group New York, New York | |
| Hudson Regional Hospital Secaucus, New Jersey | |
| Hudson Surg Ctr New York, New York | |
| Humble Vascular Surgical Center Humble, Texas | |
| Humboldt General Hospital Winnemucca, Nevada | |
| Hunter Holmes McGuire VA Med Ctr Richmond, Virginia | |
| Hunterdon Center for Surgery Flemington, New Jersey | |
| Hunterdon Medical Center Flemington, New Jersey | |
| Huntington Ambulatory Surgery Center LLC Pasadena, California | |
| Huntington Hospital Huntington, New York | |
| Huron Valley Sinai Hospital Commerce, Michigan | |
| Hyde Park Same Day Surgicenter, LLC Chicago, Illinois | |
| IU Health Ball Outpatient Surgery Center Muncie, Indiana | |
| IU Health Beltway Surgery Center Carmel, Indiana | |
| IU Health East Beltway Surgery Center Indianapolis, Indiana | |
| IU Health Frankort Hospital Frankfort, Indiana | |
| IU Health Multi Specialty Surgery Center Indianapolis, Indiana | |
| IU Health Saxony Ambulatory Surgery Center Fishers, Indiana | |
| IUH University Hospital Indianapolis, Indiana | |
| Idaho Physical Medicine and Rehabilitation Meridian, Idaho | |
| Illinois Back and Neck Institute Elmhurst, Illinois | |
| Illinois Sports Medicine & Orthopedic Surgery Center Morton Grove, Illinois | |
| Indian Creek Ambulatory Surgery Center Overland Park, Kansas | |
| Indian River Medical Center Vero Beach, Florida | |
| Indiana Pain Ctrs Evansville Evansville, Indiana | |
| Indiana Regional Medical Center Indiana, Pennsylvania | |
| Indiana Univ Health Methodist Med Indianapolis, Indiana | |
| Indu and Raj Soin Medical Center Beavercreek, Ohio | |
| Ingalls Same Day Surgery Tinley Park, Illinois | |
| Innovative Pain Treatment Surgery Center Temecula, California | |
| Innovative Procedural Center Watertown, South Dakota | |
| Innovative Solutions, LLC Houston, Texas | |
| Innovative Surgery Center Surprise, Arizona | |
| Inov8 Orthopedics Houston, Texas | |
| Insight Hosp and Med Ctr Coldwater Coldwater, Michigan | |
| Insight Hospital & Medical Center-Chicago Chicago, Illinois | |
| Insight Pain Management - Flint Flint, Michigan | |
| Inspira Medical Center Woodbury, New Jersey | |
| Inspira Medical Center Elmer Elmer, New Jersey | |
| Integrated Surgical Institute Leesport, Pennsylvania | |
| Intermountain Surg Ctr Tosh Salt Lake City, Utah | |
| Interventional & Surgical Suites of Wilkes - Barre, LLC Wilkes-Barre, Pennsylvania | |
| Interventional Pain Center Chesterfield - Satellite Chesterfield, Missouri | |
| Interventional Pain Center of Chesterfield Chesterfield, Missouri | |
| Interventional Pain Management Hobart, Indiana | |
| Interventional Pain Management Center Jonesboro, Arkansas | |
| Interventional Pain Management, LLC Munster, Indiana | |
| Interventional Pain Mgmt Valparaiso, Indiana | |
| Interventional Surgery Institute Little Rock, Arkansas | |
| Intracoastal Surgery Center Melbourne, Florida | |
| Ipc Surg Ctr Cleveland, Tennessee | |
| Ireland Grove Center for Surgery Bloomington, Illinois | |
| Irvine Surgical Partners, LLC Irvine, California | |
| Island Amb Surg Ctr Brooklyn, New York | |
| Island Health Hospital Anacortes, Washington | |
| JDS Surgical LLC Phoenix, Arizona | |
| JFK Medical Center North Campus West Palm Beach, Florida | |
| JFK Medical Center North Campus West Palm Beach, Florida | |
| Jackson General Hospital Ripley, West Virginia | |
| Jackson Surgical Center Jackson, New Jersey | |
| Jacksonville Beach Surgery Center Jacksonville Beach, Florida | |
| Jacksonville Outpatient Surgery Center Orange Park, Florida | |
| Jacobs Med Ctr La Jolla, California | |
| James H Quillen Va Med Ctr Mountain Home, Tennessee | |
| Jasper Ambulatory Surgical Center Brick, New Jersey | |
| Jefferson Methodist Hospital Philadelphia, Pennsylvania | |
| Jefferson Surgery Center Sewell, New Jersey | |
| Jefferson Surgery Center-Cherry Hill Cherry Hill, New Jersey | |
| Jefferson Surgical Center at the Navy Yard Philadelphia, Pennsylvania | |
| Jefferson Washington Twp Hosp Turnersville, New Jersey | |
| Jennie Edmundson Memorial Hospital Council Bluffs, Iowa | |
| Jersey City Medical Center Jersey City, New Jersey | |
| Jersey Shore Ambulatory Surgery Center Somers Point, New Jersey | |
| Jewett Orthopedic Institute Surgery Center Orlando, Florida | |
| Jewish Hospital - Mercy Health Cincinnati, Ohio | |
| John Peter Smith Hosp Fort Worth, Texas | |
| John T Mather Memorial Hospital Port Jefferson, New York | |
| Johns Hopkins Bayview Medical Center Baltimore, Maryland | |
| Johns Hopkins Enterprise Baltimore, Maryland | |
| Johns Hopkins Enterprise Baltimore, Maryland | |
| Johns Hopkins Health Care & Surgery Center - Bethesda Bethesda, Maryland | |
| Johns Hopkins Howard County Operating Room Columbia, Maryland | |
| Johns Hopkins Surg Ctrs Series Lutherville-Timonium, Maryland | |
| Johns Hopkins Surgery Center- White Marsh Nottingham, Maryland | |
| Johns Hopkins Surgery Centr- Howard County Columbia, Maryland | |
| Johnston Health Smithfield, North Carolina | |
| Johnston Willis Hosp Richmond, Virginia | |
| Johnston Willis Hospital North Chesterfield, Virginia | |
| Jonesboro Ambulatory Surgery Center, LLC Jonesboro, Arkansas | |
| Jordan Valley Hosp West Jordan, Utah | |
| Jordan Valley Med Ctr West Valley West Valley City, Utah | |
| JourneyLite of Cincinnati Cincinnati, Ohio | |
| Jupiter Outpatient Surgery Center Jupiter, Florida | |
| KU MedWest Shawnee Mission, Kansas | |
| Kaiser Permanente Fresno, California | |
| Kaiser Permanente Fresno Medical Center Fresno, California | |
| Kaiser Permanente Richmond Medical Center Richmond, California | |
| Kaiser Permanente San Jose San Jose, California | |
| Kansas City Orthopedic Institute Leawood, Kansas | |
| Kansas Spine & Specialty Hospital Wichita, Kansas | |
| Kansas Surgery & Recovery Center Wichita, Kansas | |
| Kansas Surgery Center Overland Park, Kansas | |
| Katherine Shaw Bethea Hospital Dixon, Illinois | |
| Kearney County Health Services Minden, Nebraska | |
| Kearney Pain Treatment Center Kearney, Nebraska | |
| Keck Medicine of USC Los Angeles, California | |
| Kentuckiana Medical Center Clarksville, Indiana | |
| Kentucky Surgery Center Lexington, Kentucky | |
| Kimel Park Surgery Center Winston-Salem, North Carolina | |
| Kings Daughters Med Ctr Brookhaven, Mississippi | |
| Kings Daughters Medical Center Ashland, Kentucky | |
| Kokomo Ambulatory Surgery Center Kokomo, Indiana | |
| Koman Family Outpatient Pavilion La Jolla, California | |
| Kumar Surgical Center Rochester Hills, Michigan | |
| Kw Neurospine Miami, Florida | |
| Ky Advanced Surgical Center, Inc. Fresno, California | |
| La Veta Surgical Center Orange, California | |
| Lafayette Gen Surgl Hosp Lafayette, Louisiana | |
| Lafayette Pain Care Lafayette, Indiana | |
| Lafayette Pain Care Lafayette, Indiana | |
| Lafayette Surgery Center Lafayette, Indiana | |
| Laguna Surgery Center Fullerton, California | |
| Lahey Clinic Burlington Burlington, Massachusetts | |
| Lahey Outpatient Center - Danvers Danvers, Massachusetts | |
| Lake Charles Memorial Hospital Lake Charles, Louisiana | |
| Lake City Surg Ctr Lake City, Florida | |
| Lake County Pain & Diagnostic Center LLC Mentor, Ohio | |
| Lake Drive Surgical Center Grand Rapids, Michigan | |
| Lake Health TriPoint Medical Center Concord, Ohio | |
| Lake Health West Med Ctr Willoughby, Ohio | |
| Lake Mary Surgery Center Lake Mary, Florida | |
| Lake Worth Surgical Center Lake Worth, Florida | |
| Lakeside Surgery Center Omaha, Nebraska | |
| Lakeview Reg Med Ctr Covington, Louisiana | |
| Lakewalk Surgery Center Duluth, Minnesota | |
| Lakewood Surgery Center Lakewood, New Jersey | |
| Lancaster Gen Health Lancaster, Pennsylvania | |
| Lancaster Specialty Surgery Center Lancaster, Ohio | |
| Langhorne Surgical Center Langhorne, Pennsylvania | |
| Lankenau Medical Center Wynnewood, Pennsylvania | |
| Lansdale Hospital Lansdale, Pennsylvania | |
| Laredo Medical Center Laredo, Texas | |
| Largo Medical Center Upper Marlboro, Maryland | |
| Larkin Community Hospital South Miami, Florida | |
| Laser And Surgery Center Palm Beach Gardens, Florida | |
| Laser Surgery Center Tempe, Arizona | |
| Laser Surgery Center-Tempe Tempe, Arizona | |
| Laservue Eye Center Santa Rosa, California | |
| Lees Summit Medical Center Lee's Summit, Missouri | |
| Legent Institute of Specialized Surgery Conroe, Texas | |
| Legent North Houston Surgical Hospital Tomball, Texas | |
| Legent Orthopedic Hospital Carrollton, Texas | |
| Legent Orthopedic and Spine San Antonio, Texas | |
| Legent Outpatient Surgery Austin Austin, Texas | |
| Legent Westover Hills Surgery Center San Antonio, Texas | |
| Lehigh Valley Hosp Dickson City Dickson City, Pennsylvania | |
| Lehigh Valley Hospital - Cedar Crest Allentown, Pennsylvania | |
| Lehigh Valley Hospital - Hecktown Easton, Pennsylvania | |
| Lehigh Valley Hospital - Muhlenberg Bethlehem, Pennsylvania | |
| Lehigh Valley Hospital-Carbon Lehighton, Pennsylvania | |
| Lehigh Valley Hospital-Schuylkill Pottsville, Pennsylvania | |
| Lenox Health Greenwich Village New York, New York | |
| Leonardtown Surg Ctr Leonardtown, Maryland | |
| Lewis Gale Hospital Salem, Virginia | |
| Lexington Clinic Asc Lexington, Kentucky | |
| Lexington Surgery Center Lexington, Kentucky | |
| Liberty Hospital Liberty, Missouri | |
| Lincoln Surgery Center Parker, Colorado | |
| Linden Oaks Surgery Center Rochester, New York | |
| Lindenhurst Surgery Center Lindenhurst, Illinois | |
| Little Company of Mary Hospital Evergreen Park, Illinois | |
| Little Rock Surgery Center Little Rock, Arkansas | |
| Logan Regional Medical Center Logan, West Virginia | |
| Loma Linda University Medical Center Loma Linda, California | |
| Loma Linda University Medical Center Loma Linda, California | |
| Lompoc Valley Medical Center Lompoc, California | |
| Long Island Community Hospital Patchogue, New York | |
| Longview Reg Med Ctr Longview, Texas | |
| Lorain Surgery Center Lorain, Ohio | |
| Los Angeles County and Univ of Los Angeles, California | |
| Louisiana Pain Care Monroe, Louisiana | |
| Loyola Ambulatory Surgery Center at Oakbrook Oakbrook Terrace, Illinois | |
| Lubbock Surg Ctr Lubbock, Texas | |
| Lynbrook Surg Ctr Lynbrook, New York | |
| MALO Center for Ambulatory Surgery Rutherford, New Jersey | |
| MAO Leawood Surgery Center, LLC Leawood, Kansas | |
| MD Pain Care, PC Conyers, Georgia | |
| MHSC Woodlands Parkway The Woodlands, Texas | |
| MUSC Health Columbia Medical Center Downtown Columbia, South Carolina | |
| MUSC Rutledge Tower Charleston, South Carolina | |
| Madison Spine Surg Ctr Flowood, Mississippi | |
| Madison Surgery Center Madison, Wisconsin | |
| Magna Surgical Cente Bedford Park, Illinois | |
| Maimonides Midwood Community Hospital Brooklyn, New York | |
| Main Line Spine Surgery Center King of Prussia, Pennsylvania | |
| Manalapan Surgery Center Manalapan, New Jersey | |
| Manchester Surgery Center Whiting, New Jersey | |
| Manchester Surgery Center Whiting, New Jersey | |
| Manhattan Surgery Center New York, New York | |
| Mankato Clinic Ltd Mankato, Minnesota | |
| Maplewood Ambulatory Surgery Center Wichita Falls, Texas | |
| Margaret R. Pardee Memorial Hospital Hendersonville, North Carolina | |
| Marin Specialty Surgery Center San Rafael, California | |
| Marion Med Cmps Marion, Ohio | |
| Marion Surgery Center LLC Ocala, Florida | |
| Marlette Reg Hosp Marlette, Michigan | |
| Marshfield Clinic Health System Marshfield, Wisconsin | |
| Marshfield Clinic-Minocqua Minocqua, Wisconsin | |
| Maryland Specialty Surgery Center Linthicum Heights, Maryland | |
| Mason City Surgery Center Mason City, Iowa | |
| Massachusetts Gen Hosp Boston, Massachusetts | |
| Matrix Surgery Center Saginaw, Michigan | |
| Mayo Clinic Jacksonville, Florida | |
| Mayo Clinic Jacksonville, Florida | |
| Mayo Clinic Health System Menomonie, Wisconsin | |
| Mayo Clinic Health System In Mankato, Minnesota | |
| Mayo Clinic Health System Northland Barron, Wisconsin | |
| Mayo Clinic Health System- La Crosse La Crosse, Wisconsin | |
| Mayo Clinic Health System-Eau Claire Eau Claire, Wisconsin | |
| Mays and Schnapp Neurospine and Memphis, Tennessee | |
| McLaren Hospital - Lapeer Lapeer, Michigan | |
| McLeod Seacoast OR Little River, South Carolina | |
| Meadowview Regional Medical Center Maysville, Kentucky | |
| Meadville Medical Center Meadville, Pennsylvania | |
| Med Univ Hosp Autg Charleston, South Carolina | |
| MedStar Franklin Square Medical Center Rosedale, Maryland | |
| MedStar Franklin Square Medical Center Rosedale, Maryland | |
| MedStar Georgetown University Hospital Washington D.C., District of Columbia | |
| MedStar Good Samaritan Hospital Baltimore, Maryland | |
| MedStar Harbor Hospital Baltimore, Maryland | |
| MedStar Health Harbor Hospital Baltimore, Maryland | |
| MedStar Health at Lafayette Center Washington D.C., District of Columbia | |
| MedStar Montgomery Medical Center Olney, Maryland | |
| MedStar Southern Maryland Hospital Center Clinton, Maryland | |
| MedStar St. Mary's Hospital Leonardtown, Maryland | |
| MedStar Union Memorial Hospital Baltimore, Maryland | |
| MedStar Union Memorial Hospital Baltimore, Maryland | |
| Medford Surg Ctr Medford, Massachusetts | |
| Medical Arts Surgery Center at South Miami South Miami, Florida | |
| Medical City Surgery Center Southlake Southlake, Texas | |
| Medical Education and Research Institute Memphis, Tennessee | |
| Medstar Surg Ctr At Annapolis Annapolis, Maryland | |
| Medstar Washington Hospital Center Washington D.C., District of Columbia | |
| Melbourne Surgery Center Melbourne, Florida | |
| Mem Hermann Southeast Hosp Houston, Texas | |
| Mem Hermann Surg Ctr Conroe Conroe, Texas | |
| Mem Hosp Miramar Miramar, Florida | |
| Mem Hosp of Carbon County Rawlins, Wyoming | |
| Mem Pain Surg Ctr Oklahoma City, Oklahoma | |
| Memorial Ambulatory Surgery Center Houston, Texas | |
| Memorial Ambulatory Surgery Center LLC Mount Holly, New Jersey | |
| Memorial Healthcare Owosso, Michigan | |
| Memorial Hermann Specialty Hosp Kingwood, Texas | |
| Memorial Hermann Surg Ctr the Woodlands Shenandoah, Texas | |
| Memorial Hermann Surgery Center - Kingsland Katy, Texas | |
| Memorial Hermann Surgery Center - Main Street Houston, Texas | |
| Memorial Hermann Surgery Center Brazoria Angleton, Texas | |
| Memorial Hermann Surgery Center Greater Heights Houston, Texas | |
| Memorial Hermann Surgery Center Main Street Houston, Texas | |
| Memorial Hermann Surgery Center Memorial Village Houston, Texas | |
| Memorial Hermann Surgery Center North Houston Endoscopy and Surgery Houston, Texas | |
| Memorial Hermann Surgical Hospital First Colony Sugar Land, Texas | |
| Memorial Hermann West Houston Surgery Center Houston, Texas | |
| Memorial Hospital Belleville Belleville, Illinois | |
| Memorial Houston Surgery Center Houston, Texas | |
| Memorial Houston Surgery Center Houston, Texas | |
| Memorial Regional Hospital South Hollywood, Florida | |
| Memorial Same Day Surgery Center Pembroke Pines, Florida | |
| Memorial Sloan Kettering New York, New York | |
| Memorial Sloan-Kettering Cancer Center Inc New York, New York | |
| MemorialCare Surgical Center Laguna Woods Laguna Woods, California | |
| Menlo Park Surgery Center Edison, New Jersey | |
| Menorah Medical Center Overland Park, Kansas | |
| Mentor Surgery Center Mentor, Ohio | |
| Mentor Surgery Center Mentor, Ohio | |
| Mercy Anderson Asc Cincinnati, Ohio | |
| Mercy Cedar Rapids Cedar Rapids, Iowa | |
| Mercy General Hospital Sacramento, California | |
| Mercy Health Allen Hosp Oberlin, Ohio | |
| Mercy Hosp Anderson Hosp Cincinnati, Ohio | |
| Mercy Hosp Lebanon Lebanon, Missouri | |
| Mercy Hospital Ardmore Ardmore, Oklahoma | |
| Mercy Hospital Carthage Carthage, Missouri | |
| Mercy Hospital Lincoln Troy, Missouri | |
| Mercy Hospital Springfield Springfield, Missouri | |
| Mercy Hospital Washington Washington, Missouri | |
| Mercy Hospital of St Louis St Louis, Missouri | |
| Mercy Medical Center Springfield, Massachusetts | |
| Mercy Medical Center - Clinton Clinton, Iowa | |
| Mercy Medical Center - Des Moines Des Moines, Iowa | |
| Mercy Medical Center - North Iowa Mason City, Iowa | |
| Mercy Medical Center Mt. Shasta Mount Shasta, California | |
| Mercy Regional Medical Center Lorain, Ohio | |
| Mercy San Juan Medical Center Carmichael, California | |
| Mercy St. Charles Hospital Oregon, Ohio | |
| MercyOne Des Moines Medical Center Des Moines, Iowa | |
| Merritt Island Surgery Center Merritt Island, Florida | |
| Mesa Outpatient Treatment Ctr Mesa, Arizona | |
| Meth Hosp Omaha, Nebraska | |
| Methodist HealthWest Omaha, Nebraska | |
| Methodist Hospitals Northlake Gary, Indiana | |
| Methodist Hospitals Southlake Merrillville, Indiana | |
| Methodist Medical Center Oak Ridge, Tennessee | |
| Metro Health and Surgery Center Cleveland, Ohio | |
| Metro Main Campus Cleveland, Ohio | |
| MetroHealth Parma Medical Center Parma, Ohio | |
| MetroWest Medical Center - Framingham Union Hospital Framingham, Massachusetts | |
| Metrohealth West 150th Health and Cleveland, Ohio | |
| Metropolitan Surgical Institute South Amboy, New Jersey | |
| Miami Surgical Center Miami, Florida | |
| Miami Surgical Suites LLC Miami, Florida | |
| Miami Valley Ambulatory Surgery Center Dayton, Ohio | |
| Miami Valley Hospital North Dayton, Ohio | |
| Miami Valley South Hospital Centerville, Ohio | |
| Michiana Surgery Center Mishawaka, Indiana | |
| Michigan Advanced Surgical Center, PLLC Warren, Michigan | |
| Michigan Institute for Advanced Surgery Lake Orion, Michigan | |
| Michigan Neurology Associates & P.C. Clinton Township, Michigan | |
| Michigan Outpatient Surgical Solutions Novi, Michigan | |
| Mid South Pain Treatment Southaven, Mississippi | |
| MidAmerica Spine Center St Louis, Missouri | |
| MidMichigan Medical Center - West Branch West Branch, Michigan | |
| Midamerica Spine Ctr Creve Coeur, Missouri | |
| Middleburg Surgery Center Middleburg, Florida | |
| Middlesex Hospital Middletown, Connecticut | |
| Midsouth Interventional Pain Jackson, Tennessee | |
| Midtown Surgery Center New York, New York | |
| Midwest Center for Day Surgery Downers Grove, Illinois | |
| Midwest Pain Management Center Lee's Summit, Missouri | |
| Milbank Area Hosp Avera Health Milbank, South Dakota | |
| Mille Lacs Hosp Onamia, Minnesota | |
| Millenia Surgery Center Orlando, Florida | |
| Millennium Surgical Center Cherry Hill, New Jersey | |
| Millman-Derr Surgicenter Rochester Hills, Michigan | |
| Milton S Hershey Medical Center Hershey, Pennsylvania | |
| Milwaukee Surgical Suites LLC Franklin, Wisconsin | |
| Minden Med Ctr Minden, Louisiana | |
| Minimally Invasive Surgery Center of New England Bedford, New Hampshire | |
| Minimally Invasive Surgical Institute Mission Viejo, California | |
| Miracle Hills Surgery Center Omaha, Nebraska | |
| Mission Advanced Pain Mgmt and Irvine, California | |
| Mission Hospital Asheville, North Carolina | |
| Mississippi Sports Medicine and Ort Flowood, Mississippi | |
| Mississippi Valley Surgery Center Davenport, Iowa | |
| Missouri Baptist Medical Center St Louis, Missouri | |
| Missouri Baptist Medical Center St Louis, Missouri | |
| Moab Regional Hospital Moab, Utah | |
| Modern Pain & Spine PC Albuquerque, New Mexico | |
| Modesto Memorial Hospital Modesto, California | |
| Monocacy Surgery Center, LLC Frederick, Maryland | |
| Monroe County Surgical Center Waterloo, Illinois | |
| Montefiore Medical Center The Bronx, New York | |
| Montefiore Mount Vernon Mount Vernon, New York | |
| Montefiore Nyack Hospital Nyack, New York | |
| Monterey Pain & Spine Institute Monterey, California | |
| Monterey Peninsula Surgery Centers Monterey, California | |
| Monterey Peninsula Surgery Centers - Munras Ave Monterey, California | |
| Montfort Surgery Center Dallas, Texas | |
| Montgomery Surgery Center Lansdale, Pennsylvania | |
| Monticello Community Surgery Center Charlottesville, Virginia | |
| Monument Health Rapid City Hospital Rapid City, South Dakota | |
| Morris County Surgical Center Parsippany, New Jersey | |
| Morristown Memorial Pain Mgmt Morristown, New Jersey | |
| Morton Hospital Taunton, Massachusetts | |
| Mount Nittany Medical Center State College, Pennsylvania | |
| Mount Sinai Medical Center Miami Beach, Florida | |
| Mountain Surgery Center West Orange, New Jersey | |
| Mountain View Hosp Payson, Utah | |
| Mountain View Hospital Idaho Falls, Idaho | |
| Mountain View Surgery Center of Gilbert Gilbert, Arizona | |
| Mountain View Surgery Center of Scottsdale Scottsdale, Arizona | |
| Mountain West Med Ctr Tooele, Utah | |
| Mt. Baker Surgery Center Bellingham, Washington | |
| Munster Surg Ctr Munster, Indiana | |
| Murdock Ambulatory Surgery Center Port Charlotte, Florida | |
| Musculoskeletal Ambulatory Surgery Center Bradenton, Florida | |
| Musculoskeletal Ambulatory Surgery Centers at Coastal Orthopedics & Sports Medicine Bradenton, Florida | |
| Museum District Ambulatory Surgery Center Houston, Texas | |
| Mymichigan Med Ctr Midland Midland, Michigan | |
| NEA Baptist Clinic Jonesboro, Arkansas | |
| NH Brunswick Medical Center Bolivia, North Carolina | |
| NH Medical Park Hospital Winston-Salem, North Carolina | |
| NMSC of St. Peters City of Saint Peters, Missouri | |
| NPI Surgery Center Lincoln, Nebraska | |
| NPI Surgery Center LLC Lincoln, Nebraska | |
| NTTC Surgery Center Mesquite, Texas | |
| NYP -Methodist Hospital Brooklyn, New York | |
| NYU Ambulatory Care Center New York, New York | |
| NYU Langone ASC - Garden City Garden City, New York | |
| NYU Langone Ambulatory Care Center New York, New York | |
| NYU Langone Hospital-Long Island (Winthrop) Mineola, New York | |
| NYU Langone Orthopedic New York, New York | |
| Napa Surgery Center Napa, California | |
| Napa Valley Surgery Center Napa, California | |
| Naperville Surgery Center Naperville, Illinois | |
| Natick Surg Ctr Natick, Massachusetts | |
| National Pain Institute Winter Park, Florida | |
| National Pain Institute Winter Park, Florida | |
| National Pain Institute Winter Park, Florida | |
| National Pain Institute - Lady Lake Lady Lake, Florida | |
| National Pain and Spine Centers Frederick, Maryland | |
| National Spine and Ortho Surgery Center - Fort Myers Fort Myers, Florida | |
| National Spine and Pain Centers McLean, Virginia | |
| National Spine and Pain Centers McLean, Virginia | |
| National Spine and Pain Centers McLean, Virginia | |
| National Spine and Pain Centers McLean, Virginia | |
| National Spine and Pain Centers McLean, Virginia | |
| National Spine and Pain Centers McLean, Virginia | |
| National Spine and Pain Centers McLean, Virginia | |
| National Spine and Pain Centers McLean, Virginia | |
| National Spine and Pain Centers McLean, Virginia | |
| National Spine and Pain Centers McLean, Virginia | |
| National Spine and Pain Centers McLean, Virginia | |
| National Spine and Pain Centers McLean, Virginia | |
| National Spine and Pain Centers McLean, Virginia | |
| National Spine and Pain Centers McLean, Virginia | |
| National Spine and Pain Centers McLean, Virginia | |
| Natividad Medical Center Salinas, California | |
| Natl Spine and Pain Ctrs Gainesville, Georgia | |
| Nebraska Medical Center Omaha, Nebraska | |
| Nebraska Pain Institute Lincoln, Nebraska | |
| Neptune Surgical Institute Neptune City, New Jersey | |
| Neurosurgery and Endovascular Associates LLC Franklin, Wisconsin | |
| Nevada Advanced Pain Spclsts Reno, Nevada | |
| Nevada Surgical Suites Las Vegas, Nevada | |
| Nevada Surgical Suites - Central Location Las Vegas, Nevada | |
| New Braunfels Surgery Center New Braunfels, Texas | |
| New Britain Surgery Center Chalfont, Pennsylvania | |
| New England Ambulatory SurgiCenter Cambridge, Massachusetts | |
| New England Baptist Hospital Boston, Massachusetts | |
| New England Center for Orthopaedic Surgery Portsmouth, New Hampshire | |
| New England Pain Care Pain and Wellness Center Peabody, Massachusetts | |
| New England Surgery Center Beverly, Massachusetts | |
| New Horizons Surgery Center Marion, Ohio | |
| New River Valley Surg Ctr Christiansburg, Virginia | |
| New York Presbyterian Allen Hospital New York, New York | |
| New York Presbyterian Hospital New York, New York | |
| New York Presbyterian Hospital New York, New York | |
| Newport Beach Surgery Center Newport Beach, California | |
| Newport Coast Surgery Center Newport Beach, California | |
| Newton Wellesley Hospital Ambulatory Care Center Newton, Massachusetts | |
| Nexus Pain Center Columbus, Georgia | |
| Noble Pain Management Columbia, Missouri | |
| Noble Pain Mangement Columbia, Missouri | |
| Non Surgical Orthopaedic Marietta, Georgia | |
| North American Spine & Pain Hainesport, New Jersey | |
| North Baldwin Infirmary Bay Minette, Alabama | |
| North Bay Regional Surgery Center Novato, California | |
| North Campus Surgery Center Creve Coeur, Missouri | |
| North Carolina Specialty Hospital Durham, North Carolina | |
| North Central Baptist Hospital San Antonio, Texas | |
| North Coast Surgery Center Oceanside, California | |
| North County Surgicenter Palm Beach Gardens, Florida | |
| North Dakota Surgery Center Grand Forks, North Dakota | |
| North East Regional Surgical Center Paramus, New Jersey | |
| North East Surgery Center Scranton, Pennsylvania | |
| North Florida Surgical Pavillion Gainesville, Florida | |
| North Haven Surgery Center North Haven, Connecticut | |
| North Idaho Pain Center Coeur d'Alene, Idaho | |
| North Jersey Ortho Spclsts Teaneck, New Jersey | |
| North Kansas City Hospital Kansas City, Missouri | |
| North Naples Surgery Center Naples, Florida | |
| North Pines Surgery Center Conroe, Texas | |
| North Point Surgery Center Fresno, California | |
| North Pointe Health and Wellness Roscoe, Illinois | |
| North Pointe Surg Ctr Lebanon, Pennsylvania | |
| North Shore Surgi-Center Smithtown, New York | |
| North Shore University Evanston Hospital Evanston, Illinois | |
| North Texas Surgery Center Sherman, Texas | |
| North Valley Surgery Center Scottsdale, Arizona | |
| NorthEast Surgicare, LLC Lakewood, New Jersey | |
| NorthShore University Health System Skokie, Illinois | |
| Northaven Surg Ctr Allen, Texas | |
| Northeast Ambulatory Center Stoneham, Massachusetts | |
| Northeast Georgia Surgery Center Gainesville, Georgia | |
| Northeast Regional Surgery Center Plains, Pennsylvania | |
| Northern Arizona Surgicenter Flagstaff, Arizona | |
| Northern Light Eastern Maine Medical Center Bangor, Maine | |
| Northern Light Interventional Pain Management Bangor, Maine | |
| Northern Louisiana Medical Center Ruston, Louisiana | |
| Northern Monmouth Regional Surgery Center Manalapan, New Jersey | |
| Northern Nevada Medical Center Sparks, Nevada | |
| Northern Ohio Surgery Center Beachwood, Ohio | |
| Northpoint Surgery Center West Palm Beach, Florida | |
| Northpointe Surgical Ctr Tooele, Utah | |
| Northshore Medical Center Miami, Florida | |
| Northside Hosp Cherokee Canton, Georgia | |
| Northway Surgery & Pain Center Halfmoon, New York | |
| Northwest Community Hospital Arlington Heights, Illinois | |
| Northwest Health - La Porte La Porte, Indiana | |
| Northwest Health Physicians' Specialty Hospital Fayetteville, Arkansas | |
| Northwest Medical Center Margate, Florida | |
| Northwest Specialty Hospital Post Falls, Idaho | |
| Northwest Spine and Laser Surgery Center Wilsonville, Oregon | |
| Northwest Surg Ctr Red Oak Houston, Texas | |
| Northwest Surgicare Arlington Heights, Illinois | |
| Northwestern Lake Forest Lake Forest, Illinois | |
| Northwestern McHenry Hospital McHenry, Illinois | |
| Northwestern Medicine Central Winfield, Illinois | |
| Norton Audubon Hospital Louisville, Kentucky | |
| Norton Brownsboro Hospital Louisville, Kentucky | |
| Norton Healthcare Inc. Louisville, Kentucky | |
| Norton St. Matthews Louisville, Kentucky | |
| Norwalk Surgery Center Norwalk, Connecticut | |
| Novamed Surgery Center of Baton Rouge Baton Rouge, Louisiana | |
| Novant Health Matthews Med Ctr Matthews, North Carolina | |
| Novant Health Midtown Outpatient Surgery Center Charlotte, North Carolina | |
| Novant Health Presbyterian Medical Center Charlotte, North Carolina | |
| Novant Kernersville Medical Hospital Kernersville, North Carolina | |
| Novi Surgery Center Novi, Michigan | |
| Noyes Memorial Hospital Dansville, New York | |
| Nura Precision Pain Management - Edina Clinic Minneapolis, Minnesota | |
| Nuvance Health Vassar Brothers Medical Center Poughkeepsie, New York | |
| Nuvation Pain Group Buena Park, California | |
| Nyu Langone Amb Care Clinic Brooklyn, New York | |
| O'Bleness Hospital Athens, Ohio | |
| OCH Regional Medical Center Starkville, Mississippi | |
| OCOM North Oklahoma City, Oklahoma | |
| OCOM South Oklahoma City, Oklahoma | |
| OMNI Pain & Precision Medicine Clinton, New York | |
| OSF Heart of Mary Medical Center Urbana, Illinois | |
| OSF Saint Anthony Medical Center Rockford, Illinois | |
| OSF Saint Anthony Medical Center Rockford, Illinois | |
| OSF St. Joseph Medical Center Bloomington, Illinois | |
| OSS Health Powder Mill York, Pennsylvania | |
| Oak ASC, LLC Bourbonnais, Illinois | |
| Oak Brook Surg Ctr Oak Brook, Illinois | |
| Oakland Surgi Center, Inc. Rochester Hills, Michigan | |
| Oakleaf Surgical Hosp Eau Claire, Wisconsin | |
| Oakleaf Surgl Hosp Altoona, Wisconsin | |
| Ocala Regional Medical Center Ocala, Florida | |
| Ocala Surgical Ctr Ocala, Florida | |
| Ochsner Clearview Med Complex Metairie, Louisiana | |
| Ochsner Med Ctr Hancock Bay Saint Louis, Mississippi | |
| Ohio County Hospital Hartford, Kentucky | |
| Ohio State East Hospital Columbus, Ohio | |
| Ohio Valley Hospital McKees Rocks, Pennsylvania | |
| Ohio Valley Surgical Hospital Springfield, Ohio | |
| Oil Ctr Surgl Plaza Lafayette, Louisiana | |
| Oklahoma Heart Hosp South Oklahoma City, Oklahoma | |
| Oklahoma Pain Physicians Oklahoma City, Oklahoma | |
| Oklahoma Spine Surgery Center Oklahoma City, Oklahoma | |
| Oklahoma Spine Surgery Center Oklahoma City, Oklahoma | |
| Oklahoma State University Medical Center Tulsa, Oklahoma | |
| Olean Gen Hosp Olean, New York | |
| Olympia Surg Ctr Olympia, Washington | |
| Omaha Ambulatory Surgery Center Omaha, Nebraska | |
| Omni Surgery Center Utica, New York | |
| On Beach Surgery Center Buena Park, California | |
| One Step Diagnostic Sugar Land Sugar Land, Texas | |
| OneCore Health Oklahoma City, Oklahoma | |
| Oneonta Specialty Svcs Oneonta, New York | |
| Onslow Memorial Hospital Jacksonville, North Carolina | |
| Optimum Pain & Regenerative Medicine Harlingen, Texas | |
| Optimun Surgical Center Phoenix, Arizona | |
| Orange County Surgery Center Westminster, California | |
| Oregon Outpatient Surgery Center Tigard, Oregon | |
| Oregon Pain Center Portland, Oregon | |
| Oregon Specialists Surgery Center Salem, Oregon | |
| Oregon Surgical Institute Beaverton, Oregon | |
| Orlando Health Amb Care Ctr Orlando, Florida | |
| Orlando Health Medical Pavilion - St. Cloud Saint Cloud, Florida | |
| Orlando Orthopaedic Outpatient Surgery Center LLC Orlando, Florida | |
| Orlando Outpatient Surgery Center Orlando, Florida | |
| Orlando Regional Medical Center Orlando, Florida | |
| Orlando Regional St. Cloud Saint Cloud, Florida | |
| Oro Valley Surgical Suites Oro Valley, Arizona | |
| Oroville Hospital Oroville, California | |
| Ortho Arkansas Little Rock, Arkansas | |
| Ortho Ny Amb Surg Ctr Clifton Park, New York | |
| OrthoArizona Scottsdale Surgery Center Scottsdale, Arizona | |
| OrthoNY Albany, New York | |
| Orthonebraska Hosp Omaha, Nebraska | |
| Orthopaedic Associates of Central Texas Surgery Center, LLC Austin, Texas | |
| Orthopaedic Surgery Center Gainesville, Florida | |
| Orthopedic Institute of Ocala Surgery Center Ocala, Florida | |
| Orthopedic Spine Care of Long Island Huntington Station, New York | |
| Orthopedic Surgery Center of Palm Beach County Boynton Beach, Florida | |
| Outpatient Procedure Ctr Wilmington, Delaware | |
| Outpatient Services East Birmingham, Alabama | |
| Outpatient Surg and Imaging Svcs Albuquerque, New Mexico | |
| Outpatient Surgery Center of Asheville Asheville, North Carolina | |
| Outpatient Surgery Center of Jonesboro Jonesboro, Arkansas | |
| Overland Park Surgery Center Lenexa, Kansas | |
| Overlook Medical Center Summit, New Jersey | |
| Owenboro Health Muhlenberg Community Hospital Greenville, Kentucky | |
| PMC Regional Hospital New Albany, Indiana | |
| PMSI - Pain Medicine Divison Pottstown, Pennsylvania | |
| PSA Ambulatory Surgical Center of Austin, LLC Austin, Texas | |
| PSA Ambulatory Surgical Center of South Austin, LLC Austin, Texas | |
| Pacific Ambulatory Surgery Center Alhambra, California | |
| Pacific Northwest Surgery Center Springfield, Oregon | |
| Pacific Restorative Center Santa Rosa, California | |
| Pacific Surg Ctr Omaha, Nebraska | |
| Pacific Surgery Center Poulsbo, Washington | |
| Pacific Surgery Center Poulsbo, Washington | |
| Pacific Surgical Institute San Diego, California | |
| Pain & Sleep Institute of Oklahoma Edmond, Oklahoma | |
| Pain Care Boise Boise, Idaho | |
| Pain Care Center of Georgia Stockbridge, Georgia | |
| Pain Center of Wyoming Valley, LLC Wilkes-Barre Township, Pennsylvania | |
| Pain Centers of Minnesota Chaska, Minnesota | |
| Pain Consultants ASC Pascagoula, Mississippi | |
| Pain Consultants of Atlanta Fayetteville, Georgia | |
| Pain Consultants of Atlanta Fayetteville, Georgia | |
| Pain Consultants of San Diego Chula Vista, California | |
| Pain Ctrs of Iowa Davenport, Iowa | |
| Pain Diagnostic and Treatment Center Sacramento, California | |
| Pain Institute of Southern Arizona Procedure Center Tucson, Arizona | |
| Pain Management Centers of America Evansville, Indiana | |
| Pain Management Specialists Rockville, Maryland | |
| Pain Management Specialists Rockville, Maryland | |
| Pain Physician New York New York, New York | |
| Pain Physicians NY New York, New York | |
| Pain Physicians of Atlanta Alpharetta, Georgia | |
| Pain Therapy Associates Schaumburg, Illinois | |
| Pain Treatment Ctrs of America Jonesboro, Arkansas | |
| Pain, Spine & Rehab, P.A. Great Bend, Kansas | |
| PainCARE, PA Overland Park, Kansas | |
| Palm Beach Gardens Regional Surgery Center Palm Beach, Florida | |
| Palm Beach International Surgery Center at The Paley Institute West Palm Beach, Florida | |
| Palmetto Health Toumey Sumter, South Carolina | |
| Palmetto Health USC Medical Group Columbia, South Carolina | |
| Palmetto Lakes Surgical Center Hialeah, Florida | |
| Palms West Hospital Loxahatchee Groves, Florida | |
| Palms West Surgicenter Loxahatchee Groves, Florida | |
| Palo Alto Med Foundation Fremont, California | |
| Palo Alto Med Foundation Warehouse Santa Clara, California | |
| Palo Verde Pain Specialists ASC Peoria, Arizona | |
| Palomar Surgl Ctr Escondido, California | |
| Paradigm Pain and Spine Lexington, Kentucky | |
| Paramount Surgical Center Houston, Texas | |
| Park Center Surgical Center Laurel, Maryland | |
| Park Center for Procedures Fort Myers, Florida | |
| Park Place Surgery Center Maitland, Florida | |
| Park Plaza Surgical Specialists Shreveport, Louisiana | |
| ParkCreek Surgery Center Coconut Creek, Florida | |
| ParkCreek Surgery Center - Parent Coconut Creek, Florida | |
| Parkland Health Ctr Farmington Farmington, Missouri | |
| Parkridge Medical Center Chattanooga, Tennessee | |
| Parkway Ambulatory Surgery Center Lyndhurst, New Jersey | |
| Parkway Surgery Center Myrtle Beach, South Carolina | |
| Parkway Surgery Center Myrtle Beach, South Carolina | |
| Pascack Valley Medical Center Westwood, New Jersey | |
| Patient Care Associates Englewood, New Jersey | |
| Peachtree Orthopedics Surgery Center Atlanta, Georgia | |
| Peak Health Surgicare of Horizon Medical Center Richardson, Texas | |
| Peak Point Midtown West Asc New York, New York | |
| Pearl Womens Ctr Portland, Oregon | |
| Pekin Memorial Hospital East Peoria, Illinois | |
| Peninsula Ortho Assocs Surg Ctr Salisbury, Maryland | |
| Penn Highlands Mon Valley Monongahela, Pennsylvania | |
| Penn Med At Rittenhouse Philadelphia, Pennsylvania | |
| Penn Medicine Radnor Radnor, Pennsylvania | |
| Penn Presbyterian Med Ctr Philadelphia, Pennsylvania | |
| Peoria Foot and Ankle Spclsts Peoria, Arizona | |
| Performance Health Surgery Center Fort Myers, Florida | |
| Performance Surgical Associates Bridgewater, New Jersey | |
| Phelps County Regional Medical Center Rolla, Missouri | |
| Phelps Memorial Hospital Center Sleepy Hollow, New York | |
| Philadelphia Pain Philadelphia, Pennsylvania | |
| Philadelphia Surgi Center Philadelphia, Pennsylvania | |
| Philadelphia Surgical Center Narberth, Pennsylvania | |
| Phoenix Eye Surgical Center dba Central Phoenix Surgical Center Phoenix, Arizona | |
| Phoenix Spine and Joint Gilbert, Arizona | |
| Physician's Surgery Center of Knoxville Knoxville, Tennessee | |
| Physicians Adventist Surgery Center Glendale, California | |
| Physicians Day Surgery Naples, Florida | |
| Physicians Outpatient Surgery Center Fort Lauderdale, Florida | |
| Physicians Regional Pine Ridge Naples, Florida | |
| Physicians Surgery Center Blytheville, Arkansas | |
| Physicians Surgery Center Of Downey Downey, California | |
| Physicians Surgery Center/Jackson Jackson, Tennessee | |
| Physicians Surgical Center Lebanon, Pennsylvania | |
| Physicians West El Paso Surg Ctr El Paso, Texas | |
| Physicians' Surgery Center Prairie Village, Kansas | |
| Physicians' SurgiCenter Toms River, New Jersey | |
| Piedmont Surgery Center Greenville, South Carolina | |
| Pikeville Medical Center Pikeville, Kentucky | |
| Pinnacle Hospital Crown Point, Indiana | |
| Pinnacle Orthopaedic Surg Ctr Woodstock, Georgia | |
| Pinnacle Outpatient Surgl Instu Tempe, Arizona | |
| Pinnacle Regional Hospital Overland Park, Kansas | |
| Pinnacle Surgery Center Covington, Louisiana | |
| Pioneer Endo and Surg Ctr Sterling Heights, Michigan | |
| Pittsburg Surgical Center Pittsburg, Kansas | |
| Plastic Surgical Center of Rapid City Rapid City, South Dakota | |
| Platinum Surgery Center Harlingen, Texas | |
| Pleasantdale Ambulatory Care West Orange, New Jersey | |
| Plum Creek Surgery Center LLC Kyle, Texas | |
| Pohlman Pain Associates Delray Beach, Florida | |
| Pohlman Pain Assocs Coral Springs, Florida | |
| Point Meadows Surg Ctr Jacksonville, Florida | |
| Port Jefferson Surgery Center Port Jefferson Station, New York | |
| Portsmouth Regional Ambulatory Surgery Center Portsmouth, New Hampshire | |
| Portsmouth Regional Hospital Portsmouth, New Hampshire | |
| Pottstown Hospital Pottstown, Pennsylvania | |
| Poway Surgery Center Poway, California | |
| Precision Ortho and Sports Laurel, Maryland | |
| Precision Pain care Lancaster, Ohio | |
| Precision Regenerative and Functional Medicine West Lake Hills, Texas | |
| Precision Surg Ctr Texarkana, Texas | |
| Precision Surg Ctr Texarkana, Texas | |
| Precision Surgical Center of NWA Rogers, Arkansas | |
| PrecisionCare Surgery Center East Setauket, New York | |
| Preferred Surgicenter Orland Park, Illinois | |
| Premier Endoscopy Surgery Center Gilbert, Arizona | |
| Premier Orthopaedic Surgery Center - Nashville Nashville, Tennessee | |
| Premier Outpatient Surgery Center Colton, California | |
| Premier Pain Centers Shrewsbury, New Jersey | |
| Premier Pain Professionals (Tilden Surgery Center) Pottsville, Pennsylvania | |
| Premier Pain Solutions Dallas, Texas | |
| Premier Surgery Center Brunswick, Georgia | |
| Premier Surgery Center Brunswick, Georgia | |
| Premier Surgery Center Brunswick, Georgia | |
| Premier Surgery Center of Louisville Louisville, Kentucky | |
| Premier Surgery Center of Sarasota Sarasota, Florida | |
| Premier Surgery Center/Atrium Health Wake Forest Baptist High Point, North Carolina | |
| Premier Surgical Center Marlton, New Jersey | |
| Premier Surgical Center Marlton, New Jersey | |
| Premier Surgical Center of Michigan Clinton Township, Michigan | |
| Presbyterian Medical Center Philadelphia, Pennsylvania | |
| Prescott OutPatient Surgery Center Prescott, Arizona | |
| Presence St Joseph Med Ctr Joliet, Illinois | |
| Presidio Surg Ctr San Francisco, California | |
| Preston Surg Ctr Frisco, Texas | |
| Preva Surgicare Spring, Texas | |
| Prime Surg Ctr Indianapolis, Indiana | |
| Prince Frederick Surg Ctr Prince Frederick, Maryland | |
| Prince William Surgery Center Manassas, Virginia | |
| Prisma Health Outpatient Surgery Maryville, Tennessee | |
| Prisma Health-Upstate - Materials Distribution Center Simpsonville, South Carolina | |
| ProHealth Ambulatory Surgery Center New Hyde Park, New York | |
| Progress West Hospital O'Fallon, Missouri | |
| Proliance Eastside Surgery Center Kirkland, Washington | |
| Proliance Surgery Center Renton, Washington | |
| Prosser Memorial Hospital Prosser, Washington | |
| Providence Little Company of Mary Medical Center San Pedro San Pedro, California | |
| Providence Queen of the Valley Medical Center Napa, California | |
| Providence Surgery Center Mount Juliet, Tennessee | |
| Puget Sound Pain Clinic Tukwila, Washington | |
| Quad City Ambulatory Surgery Center Moline, Illinois | |
| Quail Surgical and Pain Management Center Reno, Nevada | |
| Queen of the Valley Hosp West Covina, California | |
| RAYUS Radiology - Woodbury ASC Woodbury, Minnesota | |
| RWJ Endosurgical Center East Brunswick, New Jersey | |
| RWJ University Hospital - N Brunswick New Brunswick, New Jersey | |
| Radiance Surgery Center Bridgeville, Pennsylvania | |
| Radiance Surgery Center Bridgeville, Pennsylvania | |
| Raleigh Gen Hosp Beckley, West Virginia | |
| Raleigh General Hospital Beckley, West Virginia | |
| Raleigh Neurosurgical and Spine Surgery Center Raleigh, North Carolina | |
| Rancho Bernardo Surgery Center San Diego, California | |
| Raritan Valley Surgery Center Somerset, New Jersey | |
| Reclaimability Pain Svcs Linwood, New Jersey | |
| Red Rock Surgery Center Las Vegas, Nevada | |
| Red Rocks Surgery Center Golden, Colorado | |
| Redlands Mesa Surgery Center Grand Junction, Colorado | |
| Redwood City Medical Center - Kaiser Permanente Redwood City, California | |
| Redwood Surgery Center Castro Valley, California | |
| Regenerative Institute of Newport Beach Newport Beach, California | |
| Regional West Medical Center Scottsbluff, Nebraska | |
| Rehabilitation Institute of Michigan Detroit, Michigan | |
| Rehabilitation Institute of Michigan Main Campus Detroit, Michigan | |
| Reid Outpatient Surgery & End Richmond, Indiana | |
| Rembrandt Outpatient Surgery Mesa, Arizona | |
| Renaissance Surgery Center Fresno, California | |
| Renown South Meadows Medical Center Reno, Nevada | |
| Revive Ortho Spne and Sports Lithia Springs, Georgia | |
| Rex HealthCare Raleigh, North Carolina | |
| Riceland Surgery Center Beaumont, Texas | |
| Richmond Pain Management ASC Staten Island, New York | |
| Richmond University Medical Center Staten Island, New York | |
| Ridgefield Surgical Center Ridgefield, Connecticut | |
| Ridgeview Medical Center Waconia, Minnesota | |
| Rinehart Surgery Center Lake Mary, Florida | |
| Rio Grande Pain Team Weslaco, Texas | |
| Riva Road Surgery Center Annapolis, Maryland | |
| River City Surg Ctr Jacksonville, Florida | |
| River North Same Day Surgery Chicago, Illinois | |
| River Oaks Hospital and Clinics Houston, Texas | |
| Riverfront Surgery Center Chattanooga, Tennessee | |
| Rivers Edge Surg Ctr Rancho Mirage, California | |
| Riverside Med Ctr Kankakee, Illinois | |
| Riverside Surgical Center Jacksonville, Florida | |
| Rivertown Surgery Center Conway, South Carolina | |
| Riverview Ambulatory Surgical Center Kingston, Pennsylvania | |
| Riverview Health Crookston, Minnesota | |
| Riverview Health Institute Dayton, Ohio | |
| Riverview Medical Center Red Bank, New Jersey | |
| Riverwalk Ambulatory Surgery Center Bradenton, Florida | |
| Roane General Hospital Spencer, West Virginia | |
| Rochelle Community Hospital Rochelle, Illinois | |
| Rochester ASC Rochester, New York | |
| Rockford Ambulatory Surgery Center Rockford, Illinois | |
| Rogue Valley Surg Ctr Medford, Oregon | |
| Roseville Surgery Center Roseville, California | |
| Royal Oak Surgical Center Royal Oak, Michigan | |
| Rush Oak Brook Surgery Center Oak Brook, Illinois | |
| Rush Oak Park Hospital Oak Park, Illinois | |
| Rush SurgiCenter Chicago, Illinois | |
| Rush Univ Med Ctr Chicago, Illinois | |
| Ruxton Surgi Center Towson, Maryland | |
| SCA Danbury Surgery Center Danbury, Connecticut | |
| SCA Guilford Surgery Center Guilford, Connecticut | |
| SMART Surgery Center Arcadia, California | |
| SOG Surgery Center Tupelo, Mississippi | |
| SRMC Surg and Outpatient Pavilion Columbiana, Ohio | |
| SSM Health - St. Mary's Hospital Madison, Wisconsin | |
| SSM Health St. Mary's Hospital - Jefferson City Jefferson City, Missouri | |
| SSM St. Clare Surgical Center Fenton, Missouri | |
| STHS - Edinburg Hospital Edinburg, Texas | |
| Sacred Heart Med Park at Desitin Destin, Florida | |
| Sahara Surgery Center Las Vegas, Nevada | |
| Saint Alphonsus Medical Center Baker City Baker City, Oregon | |
| Saint Alphonsus Medical Center Boise Boise, Idaho | |
| Saint Alphonsus Medical Center Ontario Ontario, Oregon | |
| Saint Anne's Hospital: Southern New England Surgical Center Attleboro, Massachusetts | |
| Saint Francis Hospital-Bartlett Bartlett, Tennessee | |
| Saint John Hospital Leavenworth, Kansas | |
| Saint Joseph East Hospital Lexington, Kentucky | |
| Saint Joseph Lexington Lexington, Kentucky | |
| Saint Luke's Health System Overland Park, Kansas | |
| Saint Luke's Hospital of Kansas City Kansas City, Missouri | |
| Saint Luke's Northland Kansas City, Kansas | |
| Saint Luke's Pain Management Center Kansas City, Missouri | |
| Saint Luke's South Surgery Center LLC. Overland Park, Kansas | |
| Salem ASC Salem, New Jersey | |
| Salem Cmnty Hosp Salem, Ohio | |
| Salem Hospital Salem, Oregon | |
| Salinas Surgery Center Salinas, California | |
| Samaritan Endoscopy Center Los Gatos, California | |
| Samaritan Healthcare Moses Lake, Washington | |
| Samaritan Med Ctr Watertown, New York | |
| Same Day Procedures Clifton, New Jersey | |
| Same Day Surg Ctr of Central New Jersey Edison, New Jersey | |
| Same Day Surgery Center Rapid City, South Dakota | |
| Samson Pain Center (ASC) Woodstock, Georgia | |
| San Antonio Military Med Ctr San Antonio, Texas | |
| San Carlos Clinic San Carlos, California | |
| San Francisco Hospital San Francisco, California | |
| San Francisco Medical Center San Francisco, California | |
| San Gabriel Ambulatory Surgery Center San Gabriel, California | |
| San Gabriel Valley Med Ctr San Gabriel, California | |
| San Leandro Surgery Center San Leandro, California | |
| San Mateo Surgery Center San Mateo, California | |
| Sanford Bemidji Med Ctr Bemidji, Minnesota | |
| Sanford Medical Center Fargo, North Dakota | |
| Santa Barbara Outpatient Surgery Center LLC Santa Barbara, California | |
| Santa Clarita Surgery Center Santa Clarita, California | |
| Santa Cruz Valley Regional Hospital Green Valley, Arizona | |
| Santa Fe Surgery Center LLC Lady Lake, Florida | |
| Santa Rosa Surgical Services Santa Rosa, California | |
| Santan Surgery Center Gilbert, Arizona | |
| Sapna Surg Ctr of Potomac Potomac, Maryland | |
| Sarah Bush Lincoln Health Ctr Mattoon, Illinois | |
| Sarasota Surgery Center Sarasota, Florida | |
| Saratoga Surgical Center Corpus Christi, Texas | |
| Sasco Hill Surgery Center Southport, Connecticut | |
| Saunders Medical Center Wahoo, Nebraska | |
| Saxon Surgery Center Thousand Oaks, California | |
| Scottsbluff Surg Ctr Scottsbluff, Nebraska | |
| Scripps Encinitas Surgery Center Encinitas, California | |
| Scripps La Jolla Hospital La Jolla, California | |
| Scripps Mercy Surgery Pavilion San Diego, California | |
| Sea Surgery Center Seal Beach, California | |
| Seashore Surgical Institute Brick, New Jersey | |
| Seaside Surgery Center Naples, Florida | |
| Sebastian River MC Steward Sebastian, Florida | |
| Selby Gen Hosp Marietta, Ohio | |
| Select Physicians Surgery Center Tampa, Florida | |
| Senate Street Surgery Center Indianapolis, Indiana | |
| Sentara RMH Medical Center Harrisonburg, Virginia | |
| Serenity Surgical Munster, Indiana | |
| Seva Pain and Wellness Lewisville, Texas | |
| Sheridan Community Hospital Sheridan, Michigan | |
| Shoreline Surgery Center LLC Long Beach, California | |
| Shrewsbury Surgery Center Shrewsbury, New Jersey | |
| Sidney Reg Med Ctr Sidney, Nebraska | |
| Sierra Medical Center El Paso, Texas | |
| Sierra Surgery Hospital Carson City, Nevada | |
| Signe Spine Surgl Ctr Mt. Pleasant, South Carolina | |
| Silicon Valley ASC Los Gatos, California | |
| Siloam Springs Regional Hospital Siloam Springs, Arkansas | |
| Silver Cross Surgery Center New Lenox, Illinois | |
| Simcare ASC Mount Airy, Maryland | |
| Singing River Gulfport Gulfport, Mississippi | |
| Skyway Surgery Center St. Petersburg, Florida | |
| Smoke Ranch Surgery Center Las Vegas, Nevada | |
| Somerset Community Hospital Somerset, Pennsylvania | |
| Source Healthcare Santa Monica, California | |
| Source Surgery Center Santa Monica, California | |
| South Austin Surgery Center Austin, Texas | |
| South Bend Clinic ASC South Bend, Indiana | |
| South Bend Specialty Surgery Center Granger, Indiana | |
| South Brooklyn Health Brooklyn, New York | |
| South Central Regional Medical Center Laurel, Mississippi | |
| South Florida Surgery Center South Miami, Florida | |
| South Hills Surgery Center West Mifflin, Pennsylvania | |
| South Kansas City Surgicenter Overland Park, Kansas | |
| South Lake Hosp Clermont, Florida | |
| South Miami Hospital Miami, Florida | |
| South Portland Surgical Center Tualatin, Oregon | |
| South Seminole Medical Center Longwood, Florida | |
| South Shore Surgery Bay Shore, New York | |
| South Tampa Surgery Center, LLC Tampa, Florida | |
| South Valley Surgical Center San Tan Valley, Arizona | |
| Southeast Hospital Cape Girardeau, Missouri | |
| Southeast Michigan Surgical Hospital Warren, Michigan | |
| Southeastern Ambulatory Surgery Center, LLC Lumberton, North Carolina | |
| Southeastern Orthopaedics Surgery Center Douglas, Georgia | |
| Southeastern Spine Institute ASC Mt. Pleasant, South Carolina | |
| Southern Arizona Va Health Care Sys Tucson, Arizona | |
| Southern Grace Pain and Regenerative Medicine Mt. Pleasant, South Carolina | |
| Southern Illinois Healthcare Distribution Center Carbondale, Illinois | |
| Southern Pain and Spine - Jasper Jasper, Georgia | |
| Southern Plains Med Ctr Chickasha, Oklahoma | |
| Southern Surgery Center Hattiesburg, Mississippi | |
| Southern Surgical Center Gray, Louisiana | |
| Southern Tennessee Reg Health Winchester, Tennessee | |
| Southside Hospital Bay Shore, New York | |
| Southside Pain Specialists Birmingham, Alabama | |
| Southside Regional Med Ctr Petersburg, Virginia | |
| Southwest Connecticut Surgery Center Wilton, Connecticut | |
| Southwest Lincoln Surgery Center Lincoln, Nebraska | |
| Southwest Ohio Pain Management Ambulatory Surgery Center Mason, Ohio | |
| Southwest Ohio Surgery Center Middletown, Ohio | |
| Southwest Spine and Pain Ctr Logan, Utah | |
| Space Coast Surgery Center Merritt Island, Florida | |
| Spanish Hills Surgery Center Camarillo, California | |
| Spartan Health Surgicenter Monongahela, Pennsylvania | |
| Specialists One Day Surgery Syracuse, New York | |
| Specialists One Day Surgery Syracuse, New York | |
| Speciality Surg Ctr Las Vegas, Nevada | |
| Specialized Outpatient Surg Ctr For Boynton Beach, Florida | |
| Specialty Surgery Center of CNY Liverpool, New York | |
| Specialty Surgery Center of Middletown Middletown, New Jersey | |
| Specialty Surgical Center of Beverly Hills Beverly Hills, California | |
| Specialty Surgical Center of North Brunswick North Brunswick, New Jersey | |
| Specialty Surgl Ctr of Encino Encino, California | |
| Spectrum Health Grand Rapids Grand Rapids, Michigan | |
| Spectrum Pain Clinic Jackson, Tennessee | |
| Spectrum Pain Clinic Jackson, Tennessee | |
| Spicewood Surg Ctr Austin, Texas | |
| Spine & Sports Surgery Center Campbell, California | |
| Spine Solutions of Green Bay, LLC Green Bay, Wisconsin | |
| Spine Solutions of Sheboygan, LLC Sheboygan, Wisconsin | |
| Spine Solutions of West Bend West Bend, Wisconsin | |
| Spine and Neuro, Health and Wellness Center, LLC Lake Geneva, Wisconsin | |
| Spine and Pain Clinics of North Fairfax, Virginia | |
| Spine and Pain Physicians Surgery Center Smyrna, Tennessee | |
| Spinecare Corpus Christi, Texas | |
| Sports and Spine Pain Management Havre de Grace, Maryland | |
| SportsOrtho Surg Ctr Harlingen, Texas | |
| Spring Creek Surgical Center Providence, Utah | |
| Spring Hospital Spring, Texas | |
| Spring Hospital Spring, Texas | |
| Springfield Regional Medical Center Springfield, Ohio | |
| Ssm Health St Louis Univ Hosp South St Louis, Missouri | |
| St Anthony Hospital Oklahoma City, Oklahoma | |
| St Anthony Hospital Oklahoma City, Oklahoma | |
| St Charles Hospital Port Jefferson, New York | |
| St Charles Surgical Center Thousand Oaks, California | |
| St Cloud Hosp Saint Cloud, Minnesota | |
| St Elizabeth's Medical Center Boston, Massachusetts | |
| St Johns Health System Inc Springfield, Missouri | |
| St Johns Riverside Hospital Yonkers, New York | |
| St Joseph College Station College Station, Texas | |
| St Joseph Hosp Bangor, Maine | |
| St Joseph Pain Mgmt Ctr Warren, Ohio | |
| St Lukes Health System Boise, Idaho | |
| St Lukes Hosp Cedar Rapids, Iowa | |
| St Lukes Hosp Monroe CMPS Stroudsburg, Pennsylvania | |
| St Lukes Hospital San Francisco, California | |
| St Mary Medical Center Apple Valley, California | |
| St Marys Hosp Leonardtown, Maryland | |
| St Marys Med Ctr Huntington, West Virginia | |
| St Marys Regional Med Ctr Enid, Oklahoma | |
| St Nicholas Hosp Sheboygan Surg Ctr Sheboygan, Wisconsin | |
| St Peters Ambulatory Surgery Center City of Saint Peters, Missouri | |
| St Vincents Birmingham Birmingham, Alabama | |
| St Vincents One Nineteen Health and Birmingham, Alabama | |
| St. Alexius Medical Center Bismarck, North Dakota | |
| St. Alphonsus Medical Center (Boise) Boise, Idaho | |
| St. Alphonsus Medical Center Nampa Nampa, Idaho | |
| St. Anne Hospital Toledo, Ohio | |
| St. Catherine of Siena Smithtown, New York | |
| St. Elizabeth - Edgewood Edgewood, Kentucky | |
| St. Elizabeth - Florence Florence, Kentucky | |
| St. Francis Hospital Roslyn, New York | |
| St. Francis Mooresville Surgery Center Mooresville, Indiana | |
| St. John Hospital and Medical Center Detroit, Michigan | |
| St. Joseph Health Santa Rosa, California | |
| St. Joseph Health Regional Hospital - Bryan Bryan, Texas | |
| St. Joseph Hospital Denver, Colorado | |
| St. Joseph's Wayne Hospital Wayne, New Jersey | |
| St. Lucie Surgery Center Port Saint Lucie, Florida | |
| St. Luke's Baptist Hospital San Antonio, Texas | |
| St. Luke's Miners Campus Coaldale, Pennsylvania | |
| St. Lukes Anderson County Hospital Garnett, Kansas | |
| St. Mina Interventional Pain Center Warren, Ohio | |
| Stanford Health Care San Jose, California | |
| Stanford Health Care San Jose, California | |
| Stanford Health Care San Jose, California | |
| Stanford Health Care Med Center Palo Alto, California | |
| Stanford Health Care ValleyCare Pleasanton, California | |
| Stanford HealthCare Everyville Emeryville, California | |
| Stanford Hlthcr Tri Valley Livermore, California | |
| Stanislaus Surgical Hospital Modesto, California | |
| Star Med Ctr Plano, Texas | |
| Star Valley Med Ctr Afton, Wyoming | |
| Stellar Surgical Specialties Rancho Mirage, California | |
| Stemmee Surg Ctr Somerset, New Jersey | |
| Sterling Surgical Hospital Slidell, Louisiana | |
| Stockton Surg Ctr Stockton, California | |
| Stonegate Surgery Center Austin, Texas | |
| Stony Brook Eastern Long Island Greenport, New York | |
| Stony Brook Medicine Stony Brook, New York | |
| Stony Brook University Hospital Stony Brook, New York | |
| Stratham Ambulatory Surgery Center Stratham, New Hampshire | |
| Strong Memorial Hospital - University of Rochester Rochester, New York | |
| Sturdy Memorial Hospital Attleboro, Massachusetts | |
| Suffolk Surgery Center Shirley, New York | |
| Sugar Land Surg Ctr Sugar Land, Texas | |
| Summa Pain Care Phoenix, Arizona | |
| Summerport Surgery Center Windermere, Florida | |
| Summit Healthcare Regional Medical Center Show Low, Arizona | |
| Summit Medical Center Edmond, Oklahoma | |
| Summit Spine and Joint Ctr Greenville, South Carolina | |
| Summit Spine and Joint Ctr Greenville, South Carolina | |
| Summit Spine and Joint Ctr Savannah Savannah, Georgia | |
| Summit Surg Ctr Covington, Louisiana | |
| Summit Surgery Center Hermitage, Tennessee | |
| Summit Surgery Center Hermitage, Tennessee | |
| Summit Surgical Fresno, California | |
| Summit View Surgery Center Littleton, Colorado | |
| Sun City Ambulatory Surgery Center Ruskin, Florida | |
| Sunset Lake Surg Ctr Venice, Florida | |
| Surg Ctr At South Ogden South Ogden, Utah | |
| Surg Ctr of Beverly Hills Beverly Hills, California | |
| Surg Ctr of Kalamazoo Portage, Michigan | |
| Surg Ctr of Mid Tennessee Columbia, Tennessee | |
| Surg Ctr of Peoria Peoria, Arizona | |
| Surg Spclsts Asc Fort Walton Beach, Florida | |
| SurgCenter Dunedin Dunedin, Florida | |
| SurgCenter of Glen Burnie Glen Burnie, Maryland | |
| SurgCenter of Northern Baltimore, LLC Hunt Valley, Maryland | |
| SurgCenter of St. Lucie Port Saint Lucie, Florida | |
| Surgcenter NorthEast St. Petersburg, Florida | |
| Surgcenter Northern Phoenix LLC Phoenix, Arizona | |
| Surgcenter Pinellas Largo, Florida | |
| Surgcenter of Fayetteville Fayetteville, Arkansas | |
| Surgcenter of Greater Jacksonville, LLC Jacksonville, Florida | |
| Surgcenter of Palm Beach Gardens Palm Beach Gardens, Florida | |
| Surgcenter of the Potomac Bethesda, Maryland | |
| Surgeons Choice Medical Center Southfield, Michigan | |
| Surgery Center Health Park Grand Blanc, Michigan | |
| Surgery Center at Coral Springs Coral Springs, Florida | |
| Surgery Center at Corporate Way Dayton, Ohio | |
| Surgery Center at Doral Miami, Florida | |
| Surgery Center at Flagstaff Bone and Joint Flagstaff, Arizona | |
| Surgery Center at Pointe West - Lena Rd Bradenton, Florida | |
| Surgery Center at St. Andrews Venice, Florida | |
| Surgery Center of Allentown Allentown, Pennsylvania | |
| Surgery Center of Amarillo Amarillo, Texas | |
| Surgery Center of Aventura Aventura, Florida | |
| Surgery Center of California Chula Vista, California | |
| Surgery Center of Des Moines West West Des Moines, Iowa | |
| Surgery Center of Enid Enid, Oklahoma | |
| Surgery Center of Florida Wesley Chapel, Florida | |
| Surgery Center of Lancaster, L.P. Lancaster, Pennsylvania | |
| Surgery Center of Lynchburg Lynchburg, Virginia | |
| Surgery Center of Mt Dora Mt. Dora, Florida | |
| Surgery Center of Naples Naples, Florida | |
| Surgery Center of New England Springfield, Massachusetts | |
| Surgery Center of North Florida, LLC Gainesville, Florida | |
| Surgery Center of Ocala Ocala, Florida | |
| Surgery Center of Pinehurst Pinehurst, North Carolina | |
| Surgery Center of Reno Reno, Nevada | |
| Surgery Center of San Diego, LLC San Diego, California | |
| Surgery Center of South Bay Torrance, California | |
| Surgery Center of the Pacific Santa Monica, California | |
| Surgery Center of the Rockies Aurora, Colorado | |
| SurgiCare LLC Bloomington, Indiana | |
| SurgiCare of Freehold, LLC Freehold, New Jersey | |
| SurgiCare of Westside New York, New York | |
| SurgiCenter of Baltimore Owings Mills, Maryland | |
| SurgiCore Jersey City Kenilworth, New Jersey | |
| SurgiCore Jersey City Kenilworth, New Jersey | |
| SurgiCore Rockland and Bergen Surgery Center Montvale, New Jersey | |
| Surgical Arts Center Las Vegas, Nevada | |
| Surgical Center of Connecticut Bridgeport, Connecticut | |
| Surgical Center of Mount Dora Mt. Dora, Florida | |
| Surgical Center of New Albany New Albany, Indiana | |
| Surgical Center of South Jersey Mount Laurel, New Jersey | |
| Surgical Centers of Arizona Scottsdale, Arizona | |
| Surgical Hospital of Oklahoma Oklahoma City, Oklahoma | |
| Surgical Institute of Monroe Monroe, Michigan | |
| Surgical Institute of Reading Wyomissing, Pennsylvania | |
| Surgical Pain Center of the Adirondacks Plattsburgh, New York | |
| Surgical Park Center Miami, Florida | |
| Surgical Specialists at Princeton Princeton, New Jersey | |
| Surgical Specialty Center of Mid-Atlantic, LLC Bethesda, Maryland | |
| Surgical Specialty Center of Westchester Harrison, New York | |
| Surgical Studios Mullica Hill, New Jersey | |
| Surgicare of Jackson Jackson, Mississippi | |
| Surgicare of Manhattan, LLC New York, New York | |
| Surgicare of Miramar Miramar, Florida | |
| Surgicenter of Johnson County Overland Park, Kansas | |
| Surgicore Midtown/Manhattan New York, New York | |
| Surgicore North Queens Bayside, New York | |
| Surgicore North Queens Surgical Center Bayside, New York | |
| Surgicore of Saddle Brook Saddle Brook, New Jersey | |
| Susquehanna Surgery Center Bloomsburg, Pennsylvania | |
| Susquehanna Valley Pain Management Harrisburg, Pennsylvania | |
| Sutter Auburn Surgery Center Auburn, California | |
| Sutter Elk Grove Surg Ctr Elk Grove, California | |
| Sutter Lakeside Hospital Lakeport, California | |
| Sutter Sierra Surgery Center Roseville, California | |
| Sutter Tracy Community Hospital Tracy, California | |
| Swedish Amb Surg Ctr Chicago, Illinois | |
| Swedish American Med Ctr Belvidere Belvidere, Illinois | |
| Swedish Covenant Hosp Chicago, Illinois | |
| Swedishamerican Health System Rockford, Illinois | |
| Sycamore Hospital Miamisburg, Ohio | |
| Synergy Spine & Orthopedic Surgery Center, LLC Warren, Michigan | |
| Synergy Spine and Pain Ctr Glenn Dale, Maryland | |
| Synergy Surg Ctr Englewood, Colorado | |
| Synergy Surgical Center, LLC Westlake Village, California | |
| TOPS Specialty Hospital Houston, Texas | |
| Tanner Medical Center Carrollton, Georgia | |
| Taylor Station Surgical Center Columbus, Ohio | |
| TeamMD Surgery Center Woodland Park, New Jersey | |
| Teaneck Surgery Center Teaneck, New Jersey | |
| Temple University Hospital Philadelphia, Pennsylvania | |
| Terre Haute Surgical Center Terre Haute, Indiana | |
| Texas Health Surg Ctr Rockwall Rockwall, Texas | |
| Texas Ortho Ctr of Excellence Corpus Christi, Texas | |
| Texas Pain Physicians Waxahachie, Texas | |
| Texas Precision Surgery Center Corpus Christi, Texas | |
| Texas Spine & Joint Hospital Tyler, Texas | |
| Thayer County Health Services Hebron, Nebraska | |
| The Advanced Center for Surgery Vero Beach, Florida | |
| The Center For Outpatient Medicine Bloomington, Illinois | |
| The Center for Minimally Invasive Surgery Munster, Indiana | |
| The Charlotte Hungerford Hospital Torrington, Connecticut | |
| The Christ Hospital Cincinnati, Ohio | |
| The Ctr For Outpatient Surg Tinton Falls, New Jersey | |
| The Gables Surgical Center Coral Gables, Florida | |
| The Heights Hospital Houston, Texas | |
| The Imaging and Spine Center - UNC Hospitals Chapel Hill, North Carolina | |
| The Medical Center of Southeast Texas-Beaumont Campus Beaumont, Texas | |
| The Ohio Pain Clinic Centerville, Florida | |
| The Orthopedic Surgery Center Youngstown, Ohio | |
| The Outpatient Center of Delray Delray Beach, Florida | |
| The Pain Management Center of Meridian Meridian, Mississippi | |
| The Pain Treatment Center - URMC Rochester, New York | |
| The Pain Treatment Center, Inc. Lexington, Kentucky | |
| The Saint Francis Hospital Center for Pain Relief Charleston, West Virginia | |
| The Spine Care Manassas, Virginia | |
| The Surgery Center Victoria, Texas | |
| The Surgery Center Victoria, Texas | |
| The Surgery Center LLC Franklin, Wisconsin | |
| The Surgery Center at Edgewater Fort Mill, South Carolina | |
| The Surgery Center at Fort Washington Fort Washington, Pennsylvania | |
| The Surgery Center at Lone Tree Lone Tree, Colorado | |
| The Surgery Center at Orthopedic Associates LL Poughkeepsie, New York | |
| The Surgery Center at TGH Brandon Healthplex Tampa, Florida | |
| The Surgery Center of Chester County Exton, Pennsylvania | |
| The Surgery Center of Cleveland Cleveland, Tennessee | |
| The Surgery Center of Columbia Columbia, Missouri | |
| The Surgery Center of Ft. Lauderdale Lauderdale Lakes, Florida | |
| The Surgical Center at Columbia Orthopaedic Group Columbia, Missouri | |
| The Surgical Center of the Treasure Coast Port Saint Lucie, Florida | |
| The Surgical Pavilion Little Rock, Arkansas | |
| The Univ of Alabama At Birmingham Birmingham, Alabama | |
| The University of Toledo Medical Center Toledo, Ohio | |
| The Vancouver Clinic Inc. Vancouver, Washington | |
| ThedaCare Inc. - Neenah Neenah, Wisconsin | |
| ThedaCare Medical Center - Orthopedic Spine & Pain Appleton, Wisconsin | |
| ThedaCare Regional Medical Center-Appleton Appleton, Wisconsin | |
| Thibodaux Regional Health System Thibodaux, Louisiana | |
| Thomas Jefferson Univ Hosp Haddonfield, New Jersey | |
| Thomas Johnson Surgery Center Frederick, Maryland | |
| Thomas Mem Hosp South Charleston, West Virginia | |
| Thousand Oaks Surgery Center Thousand Oaks, California | |
| Three Gables Surgery Center Proctorville, Ohio | |
| Three Rivers Health Three Rivers, Michigan | |
| Tilden Asc Hamburg, Pennsylvania | |
| Timonium Surgery Center Timonium, Maryland | |
| Tinley Woods Surgery Center Tinley Park, Illinois | |
| Titus County Mem Hosp Mount Pleasant, Texas | |
| Titusville Surgery Center Titusville, Florida | |
| Toledo Clinic Outpatient Surgery Toledo, Ohio | |
| Toms River Surgery Center Toms River, New Jersey | |
| Total Body Pain Institute Grand Island, Nebraska | |
| Total Pain Care Meridian, Mississippi | |
| Touchton Surgery Center Jacksonville, Florida | |
| Towne Centre Surgery Center Saginaw, Michigan | |
| Townsen Mem Surg Ctr Katy Katy, Texas | |
| Townsen Memorial ASC Medical Center Houston, Texas | |
| Townsen Memorial Hospital Humble, Texas | |
| Townsen Memorial Surgery Center Spring Spring, Texas | |
| Townsen Memorial Surgery Center-Kingwood Kingwood, Texas | |
| Townsend Mem Hosp West Houston, Texas | |
| Trails Edge Surgery center LLC Bonita Springs, Florida | |
| Trevose Specialty Care Surgical Center Trevose, Pennsylvania | |
| Tri-State Memorial Hospital Clarkston, Washington | |
| Tri-State Surgical Center Martinsburg, West Virginia | |
| TriHealth Evendale Hospital Cincinnati, Ohio | |
| Trinitas Hospital Elizabeth, New Jersey | |
| Trinity Bettendorf Hosp Bettendorf, Iowa | |
| Trinity Mother Frances Hospital Tyler, Texas | |
| Trinity Surgery Center San Jose, California | |
| Trinity Surgical and Pain Management dba Performance Surgical Associates Bridgewater, New Jersey | |
| Truman Medical Center Kansas City, Missouri | |
| Trumbull Regional Medical Center Warren, Ohio | |
| Tucson Med Ctr Tucson, Arizona | |
| Tucson Med Ctr Rincon Tucson, Arizona | |
| Tucson Surgery Center Tucson, Arizona | |
| Tufts Med Ctr Boston, Massachusetts | |
| Tulsa Amb Procedure Tulsa, Oklahoma | |
| Tulsa Procedure Suites Tulsa, Oklahoma | |
| Turkey Creek Medical Center (Tennova) Knoxville, Tennessee | |
| Tuscaloosa Surgery Center Tuscaloosa, Alabama | |
| Twin Cities Pain Clinic and Surgery Center Edina, Minnesota | |
| Twin Cities Pain Clinic- Burnsville Burnsville, Minnesota | |
| Twin Cities Surg Ctr Maplewood Maplewood, Minnesota | |
| Twin Cities Surgery Center Festus, Missouri | |
| Two Rivers Surgical Center Eugene, Oregon | |
| Two Twelve Surgery Center Chaska, Minnesota | |
| Tyler Tx Asc Tyler, Texas | |
| U of M Sparrow Eaton Hospital Charlotte, Michigan | |
| U.T MD Anderson Cancer Center Houston, Texas | |
| UC Davis Medical Cetner-Lawrence Ellison Ambulatory Care Building Sacramento, California | |
| UCI Medical Center- Central Distribution Warehouse - Dyer Santa Ana, California | |
| UCLA Medical Center Santa Monica Santa Monica, California | |
| UCLA-Thousand Oaks Thousand Oaks, California | |
| UCSD Health MOP San Diego, California | |
| UCSD Medical Center San Diego, California | |
| UCSF Medical Center San Francisco, California | |
| UF Health Shands Hospital Gainesville, Florida | |
| UF Health Shands Hospital Gainesville, Florida | |
| UF Health Shands Hospital Gainesville, Florida | |
| UH Portage Medical Center Ravenna, Ohio | |
| UH Samaritan Medical Center Ashland, Ohio | |
| UHealth Miami Med Ctr North Miami, Florida | |
| UIC Medical Center- University of Illinois Medical Center Chicago, Illinois | |
| UK Interventional Pain Associates Lexington, Kentucky | |
| UNC Hospitals - Hillsborough Campus Hillsborough, North Carolina | |
| UNC Hospitals - Shared Services Durham, North Carolina | |
| UNC Lenoir Health Care Kinston, North Carolina | |
| UTMB Health League City Campus Hospital League City, Texas | |
| Ucsd Med Ctr Hillcrest San Diego, California | |
| Uintah Basin Medical Center Roosevelt, Utah | |
| Unicare Surgery Center Anaheim, California | |
| Union County Surgery Center Union, New Jersey | |
| Union Hospital Terre Haute, Indiana | |
| United Medical Park ASC, LLC Waterloo, Iowa | |
| United Memorial Medical Center Sugar Land, Texas | |
| United Memorial Medical Center Sugar Land, Texas | |
| United Memorial Medical Center - North Hospital Houston, Texas | |
| United Surgery Center-Temecula Temecula, California | |
| UnityPoint Health Waterloo Waterloo, Iowa | |
| UnityPoint Methodist Comprehensive Pain Management Center Peoria, Illinois | |
| Univ Health Surg Ctr Mac San Antonio, Texas | |
| Univ Hosp San Antonio, Texas | |
| Univ Hosps Conneaut Medic Conneaut, Ohio | |
| Univ Hosps Geneva Med Ctr Geneva, Ohio | |
| Univ Ortho Assocs Somerset, New Jersey | |
| Univ of California Davis Sacramento, California | |
| Univ of Florida Health Jacksonville Jacksonville, Florida | |
| Univ of Maryland Orthopaedics Columbia, Maryland | |
| Univ of Miami Sylvester Miami, Florida | |
| Univ of Michigan Univ Hosp Ann Arbor, Michigan | |
| Univ of Mississippi Med Ctr Jackson, Mississippi | |
| Univ of Texas Southwestern Med Ctr Dallas, Texas | |
| Univ of Vermont Med Williston, Vermont | |
| University Center for Ambulatory Surgery Somerset, New Jersey | |
| University Hospital San Antonio, Texas | |
| University Hospitals Ahuja Medical Center Beachwood, Ohio | |
| University Hospitals Cleveland Medical Center Cleveland, Ohio | |
| University Hospitals Health System St John Medical Center Westlake, Ohio | |
| University Hospitals- Suburban South Euclid, Ohio | |
| University Pain Associates Houston, Texas | |
| University Surgery Center Murrieta, California | |
| University of Arkansas for Medical Sciences Little Rock, Arkansas | |
| University of Chicago Medical Center Chicago, Illinois | |
| University of Kansas Health System St. Francis Campus Topeka, Kansas | |
| University of Kansas Medical Center Kansas City, Kansas | |
| University of Kentucky Lexington, Kentucky | |
| University of Louisville Hospital Louisville, Kentucky | |
| University of New Mexico Hospital Albuquerque, New Mexico | |
| University of Texas Medical Branch - Clear Lake Webster, Texas | |
| University of Virginia Health System Charlottesville, Virginia | |
| University of Virginia Health System Charlottesville, Virginia | |
| Upland Hills Health Dodgeville, Wisconsin | |
| Upper Bay Surgery Center Elkton, Maryland | |
| Upper Peninsula Surgery Center Marquette, Michigan | |
| Upper Valley Dialysis ASC Mission, Texas | |
| Upstate Univ Hosp Syracuse, New York | |
| Ut Health Marc Asc San Antonio, Texas | |
| Utsw Zale Lipshy Dallas, Texas | |
| Uva Med Ctr 29 Warehouse Charlottesville, Virginia | |
| VA Hospital - Gainsville Gainesville, Florida | |
| VA Medical Center Albuquerque, New Mexico | |
| VA Medical Center - Cooper Dr Div Lexington, Kentucky | |
| VA Medical Center - Little Rock Little Rock, Arkansas | |
| VA Medical Center - Loma Linda Loma Linda, California | |
| VA Medical Center - San Diego San Diego, California | |
| VA Medical Center Augusta Augusta, Georgia | |
| VA Medical Center Cincinnati Cincinnati, Ohio | |
| VA Medical Center Cleveland Cleveland, Ohio | |
| VA Medical Center Indianapolis Indianapolis, Indiana | |
| VA Medical Center Kansas City Kansas City, Missouri | |
| VA Medical Center Pecos MSPV Las Vegas, Nevada | |
| VA Medical Center Richmond Richmond, Virginia | |
| VA New York Harbor (Margaret Cochran Corbin Campus) New York, New York | |
| VCU Health Ambulatory Surgery Center Henrico, Virginia | |
| VCU Health System Authority Richmond, Virginia | |
| VIP Surgical Center Conroe, Texas | |
| Valley Ambulatory Surgery Center McAllen, Texas | |
| Valley Ambulatory Surgery Center McAllen, Texas | |
| Valley Health Surgery Center Winchester, Virginia | |
| Valley Pain Center Huntingdon Valley, Pennsylvania | |
| Valley Surgical Ctr Bethlehem, Pennsylvania | |
| Vanguard Medical Group Michigan City, Indiana | |
| Vantage Surgery Center Medford, New Jersey | |
| Venice Regional Bayfront Health Venice, Florida | |
| Ventana Surgical Center Tarzana, California | |
| Vero Beach Surgery Center Vero Beach, Florida | |
| Vicksburg Spine Ctr Vicksburg, Mississippi | |
| Vidant Medical Center Greenville, North Carolina | |
| Vidant Roanoke Chowan Hospital- Pain Management Ahoskie, North Carolina | |
| Vidant Roanoke-Chowan Hospital Greenville Greenville, North Carolina | |
| Viewmont Surgery Center Hickory, North Carolina | |
| Village Pointe Health Center Omaha, Nebraska | |
| Vineyard Surg Ctr Orem, Utah | |
| Virginia Commonwealth Univ Henrico, Virginia | |
| Virginia Interventional Pain and Roanoke, Virginia | |
| Virginia Spine Instu Reston, Virginia | |
| Virtuous Health Centers III Scottsdale, Arizona | |
| Vista Medical Center East Waukegan, Illinois | |
| WHS East Campus Decatur, Texas | |
| WHS Pain Management Center at Southlake Southlake, Texas | |
| WI Surgery Center Milwaukee, Wisconsin | |
| WV University Hospitals Morgantown, West Virginia | |
| Wake Spine and Specialty Surg Ctr Raleigh, North Carolina | |
| WakeMed North Hospital Raleigh, North Carolina | |
| WakeMed Raleigh Campus Raleigh, North Carolina | |
| Wakemed Cary Surg Ctr Cary, North Carolina | |
| Wakemed North Family Health and Raleigh, North Carolina | |
| Walter Reed Medical Center Bethesda, Maryland | |
| Warren General Hospital Warren, Pennsylvania | |
| Washington Dc Va Med Ctr Washington D.C., District of Columbia | |
| Water Leaf Surgery Center, LTD Austin, Texas | |
| Watts Plastic Surgical Center Vineland, New Jersey | |
| Wauwatosa Surgery Center Wauwatosa, Wisconsin | |
| Waverly Health Center Waverly, Iowa | |
| Waverly Surgery Center Albany, Oregon | |
| Weiss Memorial Hospital Chicago, Illinois | |
| WellStar North Fulton Hospital Roswell, Georgia | |
| Wellington Endoscopy Center Wellington, Florida | |
| Wellspring Pain Solutions Columbus, Indiana | |
| Wellward Regenerative Medicine Lexington, Kentucky | |
| Wentworth-Douglass Hospital Dover, New Hampshire | |
| West Bend Surg Ctr Menomonee Falls, Wisconsin | |
| West Central Surgical Center Toledo, Ohio | |
| West Central Surgical Center Bayside Oregon, Ohio | |
| West Chester Surgical Suites West Chester, Ohio | |
| West Florida Surgical Suites Tampa, Florida | |
| West Georgia Surg Ctr Carrollton, Georgia | |
| West Hartford Surgery Center West Hartford, Connecticut | |
| West Jefferson Med Ctr Marrero, Louisiana | |
| West Lakes Surgery Center Clive, Iowa | |
| West Marion Community Hospital Ocala, Florida | |
| West Michigan Surgery Center Big Rapids, Michigan | |
| West Michigan Surgery Center Big Rapids, Michigan | |
| West Michigan Surgical Center Zeeland, Michigan | |
| West Morris Surgery Center Succasunna, New Jersey | |
| West Park Ambulatory Surgery Center Pinellas Park, Florida | |
| West Park Surgery Center Cape Girardeau, Missouri | |
| West Penn Hosp Pittsburgh, Pennsylvania | |
| West Plains Surgery Center West Plains, Missouri | |
| West Surgical ASC Camillus, New York | |
| Westchase Surgery Center Tampa, Florida | |
| Western Connecticut Orthopedic Surgical Center Danbury, Connecticut | |
| Western PA Surgery Center Wexford, Pennsylvania | |
| Western Reserve Hospital Cuyahoga Falls, Ohio | |
| Westown Ambulatory Center West Des Moines, Iowa | |
| Wetzel County Hospital New Martinsville, West Virginia | |
| Wheeling Hospital Wheeling, West Virginia | |
| White Hall Ambulatory Surgery Center White Hall, Arkansas | |
| Wilkes Barre General Hospital Wilkes-Barre, Pennsylvania | |
| William Bee Ririe Hospital Ely, Nevada | |
| William Jennings Bryan Dorn Va Med Columbia, South Carolina | |
| Willis-Knighton Medical Center Shreveport, Louisiana | |
| Wilmington Health ASC Wilmington, North Carolina | |
| Wilmington SurgCare Wilmington, North Carolina | |
| Windsor Mill Surg Ctr Windsor Mill, Maryland | |
| Winter Haven Ambulatory Surgical Center Winter Haven, Florida | |
| Wisconsin Spine and Pain Surg Ctr Sheboygan, Wisconsin | |
| Wisconsin Spine and Pain West Bend West Bend, Wisconsin | |
| Witham Health Services Lebanon, Indiana | |
| Woodland Heights Med Center Lufkin, Texas | |
| Wright Patterson Hospital Wright-Patterson Air Force Base, Ohio | |
| Wyatt Surg Ctr Tucson, Arizona | |
| Wyomissing Surgical Services Wyomissing, Pennsylvania | |
| Yale New Haven Health-Greenwich Hospital Greenwich, Connecticut | |
| Yale New Haven Hosp New Haven, Connecticut | |
| Yale New Haven Hosp St Raphael Cmps New Haven, Connecticut | |
| York Hosp York Village, Maine | |
| Youngstown Orthopedic Associates Youngstown, Ohio | |
| Zion Eye Institute St. George, Utah |
Testing the Addition of a New Anti-cancer Drug, M3814 (Peposertib), to the Usual Radiotherapy in Patients With Locally Advanced Pancreatic Cancer
ctrrecruit@vcu.edu
NCT04172532
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Inclusion Criteria:
* Patients must have pathologically confirmed pancreatic adenocarcinoma. Patients with alternative or mixed histologies (i.e., squamous, neuroendocrine, acinar, colloid) are not eligible
* Received 4-6 months of induction chemotherapy with fluorouracil, irinotecan, leucovorin and oxaliplatin (FOLFIRINOX), fluorouracil, liposomal irinotecan, leucovorin, oxaliplatin (NALIRIFOX), or gemcitabine/Abraxane, as per standard of care
* Patients must have locally advanced pancreatic cancer according to National Comprehensive Cancer Network (NCCN) Guidelines (version 1.2020) on pancreas protocol CT scan performed within 21 days of registration. Locally advanced disease is defined as any of the following:
* For head or uncinate process tumors:
* Solid tumor contact with superior mesenteric artery \> 180 degrees
* Solid tumor contact with the celiac axis \> 180 degrees
* Solid tumor contact with the common or proper hepatic arteries \> 180 degrees or
* For pancreatic body or tail tumors:
* Solid tumor contact of \> 180 degrees with the superior mesenteric artery or celiac axis
* Solid tumor contact with the celiac axis and aortic involvement or
* Unreconstructible superior mesenteric vein or portal vein due to tumor involvement or occlusion (can be due to tumor or bland thrombus)
* The determination of locally advanced pancreatic cancer and plan for non-operative treatment on this clinical trial must be confirmed through local multi-disciplinary review
* Measurable disease per response evaluation criteria in solid tumors (RECIST) version (v)1.1
* Age \>= 18 years. Because no dosing or adverse event data are currently available on the use of M3814 (peposertib) in combination with hypofractionated radiation in patients \< 18 years of age, children are excluded from this study, but will be eligible for future pediatric trials
* Eastern Cooperative Oncology Group (ECOG) performance status =\< 2 (Karnofsky \>= 60%)
* Leukocytes \>= 4,000/mcL
* Absolute neutrophil count \>= 1.5 x 10\^9/L.
* Hemoglobin \>= 9 g/dL
* Platelets \>= 100 x 10\^9/L
* Total bilirubin =\< 2.0 x institutional upper limit of normal (ULN)
* Aspartate aminotransferase (AST) (serum glutamic oxaloacetic transaminase \[SGOT\])/alanine aminotransferase (ALT) (serum glutamic pyruvic transaminase \[SGPT\]) =\< 3 x institutional ULN
* Creatinine =\< 1.5 x institutional ULN
* Glomerular filtration rate (GFR) \>= 51 mL/min/1.73 m\^2
* Human immunodeficiency virus (HIV)-infected patients on effective anti-retroviral therapy with undetectable viral load within 6 months are eligible for this trial
* For patients with evidence of chronic hepatitis B virus (HBV) infection, the HBV viral load must be undetectable on suppressive therapy, if indicated
* Patients with a history of hepatitis C virus (HCV) infection must have been treated and cured. For patients with HCV infection who are currently on treatment, they are eligible if they have an undetectable HCV viral load
* Female patients of childbearing potential must have a negative urine or serum pregnancy test within 72 hours prior to receiving the first dose of study medication. If the urine test is positive or cannot be confirmed as negative, a serum pregnancy test will be required. Female patients of childbearing potential and male patients must be willing to use an adequate method of contraception for the course of the study through 12 weeks after the last dose of study medication.
* Note: Abstinence is acceptable if this is the usual lifestyle and preferred contraception for the patient.
* Patients with known history or current symptoms of cardiac disease, or history of treatment with cardiotoxic agents, should have a clinical risk assessment of cardiac function. To be eligible for this trial, patients should be American Heart Association Stage B (people without current or previous symptoms of heart failure but with either structural heart disease, increased filling pressures in the heart or other risk factors) or better and New York Heart Association Functional Classification II (slight limitation of physical activity, comfortable at rest, ordinary physical activity results in fatigue, palpitation, shortness of breath or chest pain), or better
* Ability to understand and the willingness to sign a written informed consent document. Participants with impaired decision-making capacity (IDMC) who have a legally authorized representative (LAR) and/or family member available will also be eligible
Exclusion Criteria:
* Patients who have completed induction chemotherapy less than 2 weeks or more than 8 weeks prior to study enrollment
* Patients who have not recovered from adverse events due to prior anti-cancer therapy (i.e., have residual toxicities \> grade 1) with the exception of alopecia and neuropathy grade =\< 2
* Patients who are receiving any other investigational agents
* History of allergic reactions attributed to compounds of similar chemical or biologic composition to M3814 (peposertib)
* Evidence of distant metastatic disease
* More than 1 line of chemotherapy for the treatment of localized pancreatic cancer, unless the change in treatment was made only for toxicity
* Prior abdominal radiation
* Active inflammatory bowel disease or connective tissue disease
* Inability to swallow oral medications or gastrointestinal disease limiting absorption of oral agents
* History of anaphylactic reaction to iodinated intravenous (IV) contrast required for radiation simulation. Patients with mild reactions may be enrolled, but must receive premedications for contrast allergy prior to imaging
* Patients who cannot discontinue concomitant medications or herbal supplements that are strong inhibitors or strong inducers of cytochrome P450 (CYP) isoenzymes CYP3A4/5, CYP2C9, and CYP2C19. Concomitant use of substrates with a narrow therapeutic index that are metabolized by CYP1A2, CYP2B6, CYP2C8, and CYP3A4/5 are also excluded.
* Use caution with other substrates of CYP3A4/5, CYP1A2, CYP2B6, CYP2C8 and substrates of P-gp, BCRP, OCT1, OAT3, OATP1B1, OATP1B3, MATE1, and MATE-2K with a narrow therapeutic index. Close monitoring is advised.
Because the lists of these agents are constantly changing, it is important to regularly consult a frequently-updated medical reference. As part of the enrollment/informed consent procedures, the patient will be counseled on the risk of interactions with other agents, and what to do if new medications need to be prescribed or if the patient is considering a new over-the-counter medicine or herbal product. (Patient Drug Interactions Handout and Wallet Card) should be provided to patients
* Patients who cannot discontinue concomitant proton-pump inhibitors (PPIs). Patients may confer with the study doctor to determine if such medications can be discontinued. These must be discontinued \>= 5 days prior to study treatment. Patients do not need to discontinue calcium carbonate. H2 blockers and antacids are allowed.
* Patients who have received a live attenuated vaccine within 30 days of dosing with M3814 (peposertib)
* Patients with uncontrolled intercurrent illness
* Patients with psychiatric illness/social situations that would limit compliance with study requirements
* Pregnant women are excluded from this study because M3814 (peposertib) is a DNA-protein kinase (PK) inhibitor with the potential for teratogenic or abortifacient effects. Because there is an unknown but potential risk for adverse events in nursing infants secondary to treatment of the mother with M3814 (peposertib), breastfeeding should be discontinued if the mother is treated with M3814 (peposertib)
* Patients with a prior or concurrent malignancy whose natural history or treatment has the potential to interfere with the safety or efficacy assessment of this investigational regimen PROCEDURE: Biopsy Procedure, PROCEDURE: Biospecimen Collection, PROCEDURE: Computed Tomography, RADIATION: Hypofractionated Radiation Therapy, PROCEDURE: Magnetic Resonance Imaging, DRUG: Peposertib, OTHER: Placebo Administration
Locally Advanced Pancreatic Adenocarcinoma, Stage III Pancreatic Cancer AJCC v8
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Show 44 locations
Study Locations
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| Location | Contacts |
|---|---|
| City of Hope Comprehensive Cancer Center Duarte, California | Site Public Contact - (becomingapatient@coh.org) |
| City of Hope at Irvine Lennar Irvine, California | |
| Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center Lebanon, New Hampshire | |
| HaysMed Hays, Kansas | |
| Huntsman Cancer Institute/University of Utah Salt Lake City, Utah | Site Public Contact - (cancerinfo@hci.utah.edu) |
| Laura and Isaac Perlmutter Cancer Center at NYU Langone New York, New York | |
| Lawrence Memorial Hospital Lawrence, Kansas | Site Public Contact - (Stephanie.Norris@LMH.ORG) |
| Mercy Hospital Pittsburg Pittsburg, Kansas | |
| Monmouth Medical Center Long Branch, New Jersey | Site Public Contact - (mary.danish@rwjbh.org) |
| Montefiore Medical Center - Moses Campus The Bronx, New York | |
| Montefiore Medical Center-Einstein Campus The Bronx, New York | |
| Mount Sinai Hospital New York, New York | Site Public Contact - (CCTO@mssm.edu) |
| NYP/Weill Cornell Medical Center New York, New York | |
| Northwestern University Chicago, Illinois | |
| Roswell Park Cancer Institute Buffalo, New York | |
| Rutgers Cancer Institute of New Jersey New Brunswick, New Jersey | |
| Saint Barnabas Medical Center Livingston, New Jersey | Site Public Contact - (joanne.loeb@rwjbh.org) |
| Salina Regional Health Center Salina, Kansas | Site Public Contact - (mleepers@srhc.com) |
| Sibley Memorial Hospital Washington D.C., District of Columbia | Site Public Contact - (jquiver1@jhmi.edu) |
| The University of Kansas Cancer Center - Olathe Olathe, Kansas | Site Public Contact - (OlatheCCResearch@kumc.edu) |
| UC Irvine Health/Chao Family Comprehensive Cancer Center Orange, California | Site Public Contact - (ucstudy@uci.edu) |
| UCHealth University of Colorado Hospital Aurora, Colorado | |
| UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care Irvine, California | Site Public Contact - (ucstudy@uci.edu) |
| University Health Truman Medical Center Kansas City, Missouri | |
| University of California Davis Comprehensive Cancer Center Sacramento, California | |
| University of Kansas Cancer Center Kansas City, Kansas | Site Public Contact - (KUCC_Navigation@kumc.edu) |
| University of Kansas Cancer Center - Lee's Summit Lee's Summit, Missouri | Site Public Contact - (KUCC_Navigation@kumc.edu) |
| University of Kansas Cancer Center - North Kansas City, Missouri | Site Public Contact - (KUCC_Navigation@kumc.edu) |
| University of Kansas Cancer Center at North Kansas City Hospital North Kansas City, Missouri | |
| University of Kansas Cancer Center-Overland Park Overland Park, Kansas | Site Public Contact - (KUCC_Navigation@kumc.edu) |
| University of Kansas Clinical Research Center Fairway, Kansas | Site Public Contact - (KUCC_Navigation@kumc.edu) |
| University of Kansas Health System Saint Francis Campus Topeka, Kansas | |
| University of Kansas Hospital-Westwood Cancer Center Westwood, Kansas | Site Public Contact - (KUCC_Navigation@kumc.edu) |
| University of Kentucky/Markey Cancer Center Lexington, Kentucky | |
| University of Pittsburgh Cancer Institute (UPCI) Pittsburgh, Pennsylvania | |
| University of Wisconsin Carbone Cancer Center - Eastpark Medical Center Madison, Wisconsin | Site Public Contact - (clinicaltrials@cancer.wisc.edu) |
| University of Wisconsin Carbone Cancer Center - University Hospital Madison, Wisconsin | Site Public Contact - (clinicaltrials@cancer.wisc.edu) |
| VCU Massey Comprehensive Cancer Center Richmond, Virginia | Site Public Contact - (CTOclinops@vcu.edu) |
| Vanderbilt University/Ingram Cancer Center Nashville, Tennessee | |
| Wake Forest Baptist Health - Wilkes Medical Center Wilkesboro, North Carolina | |
| Wake Forest University Health Sciences Winston-Salem, North Carolina | |
| Wake Forest University at Clemmons Clemmons, North Carolina | |
| Wayne State University/Karmanos Cancer Institute Detroit, Michigan | |
| Weisberg Cancer Treatment Center Farmington Hills, Michigan |
4D-710 in Adult Patients With Cystic Fibrosis (CF)
4DMT Patient Advocacy - clinicaltrials@4DMT.com
NCT05248230
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Key Inclusion Criteria (Primary Study):
• 18 years and older
• Confirmed diagnosis of cystic fibrosis (CF) and CF lung disease including:
• Sweat chloride ≥ 60 mmol/L
• Mutation Status * Bi-allelic mutations in the CFTR gene, or * Single mutation in the CFTR gene and clinical manifestations of CF lung disease
• Ineligible for CFTR modulator therapy, or previously received modulator therapy but discontinued due to adverse effects.
• Forced expiratory volume in 1 second (FEV1) ≥ 50% and ≤ 90% of predicted (per Global Lung Function Initiative) at Screening
• Resting oxygen saturation ≥ 92% on room air at Screening Key Inclusion Criteria (Sub-Study):
• 18 years and older
• Confirmed diagnosis of cystic fibrosis (CF) and CF lung disease including:
• Sweat chloride ≥ 60 mmol/L
• Mutation Status * Bi-allelic mutations in the CFTR gene, or * Single mutation in the CFTR gene and clinical manifestations of CF lung disease
• Currently on a stable dose of CFTR modulator therapy for a minimum of 60 days prior to Screening and agree to maintain current regimen through the 24-month Observation Period
• FEV1 ≥ 40% and \< 70% predicted (per Global Lung Function Initiative) at Screening, AND/OR experienced at least 2 pulmonary exacerbations in the last year requiring intravenous antibiotics Key Exclusion Criteria (Primary and Sub Study):
• Any prior gene therapy for any indication (Exception: mRNA-based or antisense oligonucleotide therapies are not exclusionary)
• Active Mycobacterium abscessus infection requiring ongoing treatment at Screening
• Active allergic bronchopulmonary aspergillosis requiring management with systemic corticosteroids or antifungal therapy
• Smoking (e.g. cigarettes, cigars, cannabis) or use of a vaping product during the 2 months prior to screening; must agree to not smoke or use vaping products during Screening and initial 24-month observation period.
• Contraindication to systemic corticosteroid therapy
• Requires chronic use of systemic corticosteroids or immunosuppressants to treat another condition
• If no known diagnosis of cystic fibrosis related diabetes (CFRD), Type I, or Type II diabetes: Hemoglobin A1C ≥ 6.5% at Screening
• If known diagnosis of CFRD, Type I or Type II diabetes: Hemoglobin A1C \> 7.5% at Screening
• Recent history of symptomatic hyperglycemia or unstable blood glucose levels as per Investigator's assessment
• Other conditions that, in the Investigator's opinion, may interfere with management of corticosteroid-related hyperglycemia
• Body Mass Index (BMI) \< 16
• Laboratory abnormalities at screening: * ALT, AST or GGT ≥ 3 × the upper limit of normal (ULN) * Total bilirubin ≥ 2 × ULN * Hemoglobin \< 10 g/dL
• Requirement for continuous or night-time oxygen supplementation
• Known CF liver disease with evidence of multilobular cirrhosis
• History of thrombosis (excluding catheter-related thrombosis) or conditions associated with increased risk of thrombosis
• 18 years and older
• Confirmed diagnosis of cystic fibrosis (CF) and CF lung disease including:
• Sweat chloride ≥ 60 mmol/L
• Mutation Status * Bi-allelic mutations in the CFTR gene, or * Single mutation in the CFTR gene and clinical manifestations of CF lung disease
• Ineligible for CFTR modulator therapy, or previously received modulator therapy but discontinued due to adverse effects.
• Forced expiratory volume in 1 second (FEV1) ≥ 50% and ≤ 90% of predicted (per Global Lung Function Initiative) at Screening
• Resting oxygen saturation ≥ 92% on room air at Screening Key Inclusion Criteria (Sub-Study):
• 18 years and older
• Confirmed diagnosis of cystic fibrosis (CF) and CF lung disease including:
• Sweat chloride ≥ 60 mmol/L
• Mutation Status * Bi-allelic mutations in the CFTR gene, or * Single mutation in the CFTR gene and clinical manifestations of CF lung disease
• Currently on a stable dose of CFTR modulator therapy for a minimum of 60 days prior to Screening and agree to maintain current regimen through the 24-month Observation Period
• FEV1 ≥ 40% and \< 70% predicted (per Global Lung Function Initiative) at Screening, AND/OR experienced at least 2 pulmonary exacerbations in the last year requiring intravenous antibiotics Key Exclusion Criteria (Primary and Sub Study):
• Any prior gene therapy for any indication (Exception: mRNA-based or antisense oligonucleotide therapies are not exclusionary)
• Active Mycobacterium abscessus infection requiring ongoing treatment at Screening
• Active allergic bronchopulmonary aspergillosis requiring management with systemic corticosteroids or antifungal therapy
• Smoking (e.g. cigarettes, cigars, cannabis) or use of a vaping product during the 2 months prior to screening; must agree to not smoke or use vaping products during Screening and initial 24-month observation period.
• Contraindication to systemic corticosteroid therapy
• Requires chronic use of systemic corticosteroids or immunosuppressants to treat another condition
• If no known diagnosis of cystic fibrosis related diabetes (CFRD), Type I, or Type II diabetes: Hemoglobin A1C ≥ 6.5% at Screening
• If known diagnosis of CFRD, Type I or Type II diabetes: Hemoglobin A1C \> 7.5% at Screening
• Recent history of symptomatic hyperglycemia or unstable blood glucose levels as per Investigator's assessment
• Other conditions that, in the Investigator's opinion, may interfere with management of corticosteroid-related hyperglycemia
• Body Mass Index (BMI) \< 16
• Laboratory abnormalities at screening: * ALT, AST or GGT ≥ 3 × the upper limit of normal (ULN) * Total bilirubin ≥ 2 × ULN * Hemoglobin \< 10 g/dL
• Requirement for continuous or night-time oxygen supplementation
• Known CF liver disease with evidence of multilobular cirrhosis
• History of thrombosis (excluding catheter-related thrombosis) or conditions associated with increased risk of thrombosis
BIOLOGICAL: 4D-710
Cystic Fibrosis Lung
CF, Cystic Fibrosis, Gene Therapy
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Show 20 locations
Study Locations
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| Location | Contacts |
|---|---|
| Boston Children's Hospital Boston, Massachusetts | Monica Ulles - (monica.ulles@childrens.harvard.edu) |
| Johns Hopkins Hospital Baltimore, Maryland | Kaia Houtman - (khoutma1@jh.edu) |
| Massachusetts General Hospital Boston, Massachusetts | Margot Hardcastle - (mhardcastle@mgh.harvard.edu) |
| Medical University of South Carolina Charleston, South Carolina | Cameron Mathison - (mathisoc@musc.edu) |
| National Jewish Health Denver, Colorado | Jennifer Taylor-Cousar, MD - (TaylorCousarJ@NJHealth.org) Michele Gaffigan - (gaffiganm@njhealth.org) |
| Nationwide Children's Hospital Columbus, Ohio | Terri Johnson - (terri.johnson@nationwidechildrens.org) |
| Northwestern Memorial Hospital Chicago, Illinois | Rachel Nelson - (rachel.nelson@northwestern.edu) |
| Penn State Health Hershey, Pennsylvania | Diane Kitch - (dkitch@pennstatehealth.psu.edu) |
| Rainbow Babies and Children's Hospital/University Hospitals Cleveland Medical Center Cleveland, Ohio | Tia Rone - (Tia.Rone@uhhospitals.org) |
| The Hospital of the University of Pennsylvania Philadelphia, Pennsylvania | Melissa Molter - (melissa.molter@pennmedicine.upenn.edu) |
| The University of Arizona Tucson, Arizona | Elizabeth Ryan - (elizabethryan@arizona.edu) |
| The University of Texas Southwestern Medical Center Dallas, Texas | Maria McLeod - (maria.mcleod@utsouthwestern.edu) |
| University of Alabama Child Health Research Unit Birmingham, Alabama | Justin Anderson - (justinanderson@uabmc.edu) |
| University of California San Francisco San Francisco, California | Legna Betancourt - (legna.betancourt@ucsf.edu) |
| University of Florida Gainesville, Florida | Chrystal Bailey - (cbailey1@peds.ufl.edu) |
| University of Kansas Medical Center Kansas City, Kansas | Lawrence Scott - (lscott2@kumc.edu) |
| University of Miami Hospital Miami, Florida | Ivan Whitaker - (yiw2@miami.edu) |
| University of North Carolina at Chapel Hill Chapel Hill, North Carolina | |
| University of Washington Medical Center Seattle, Washington | Roshni Prabhu - (rprabhu@medicine.washington.edu) |
| Virginia Commonwealth University Health System Richmond, Virginia | Margaret K. Lessard - (margaret.lessard@vcuhealth.org) |
A Study of OCE-205 in Participants With Cirrhosis With Ascites Who Developed Hepatorenal Syndrome-Acute Kidney Injury
Clinical Operations - clinicaltrials@ocelotbio.com
NCT05309200
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Inclusion Criteria:
• Signed informed consent form (ICF) by participant or their legal/authorized representatives.
• Diagnosed with decompensated cirrhosis with ascites.
• Receiving albumin and has had appropriate diuretic withdrawal for at least 2 days prior to randomization into the study.
• Beta-blockers should be discontinued 48 hours prior to randomization, unless doctor deems necessary for appropriate medical treatment.
• No sustained improvement in renal function after both diuretic withdrawal and plasma volume expansion with albumin.
• Female participants must have a negative pregnancy test prior to randomization and agree to avoid becoming pregnant during the study and for 30 days after the end of treatment. Male participants must agree to use 2 effective contraceptive methods during the study and up to 30 days after the end of treatment.
Exclusion Criteria:
• Serum Creatinine >3.8 mg/dL.
• Large volume paracentesis (LVP ≥6L) within 4 days of randomization.
• Pulse oximeter reading of <90% on 2L or less.
• Sepsis and/or uncontrolled bacterial infection.
• Experienced shock within 72 hrs prior to screening.
• Model for End-Stage Liver Disease (MELD) score >35.
• Hypertension with a Systolic BP > 140 mmHg and/ or a Diastolic BP >100 mmHg.
• Treated with or exposed to nephrotoxic agents or has had exposure to radiographic contrast agents within 72 hrs prior to screening.
• Has superimposed acute liver injury due to drugs, or toxins except for acute alcoholic hepatitis.
• Proteinuria greater than 500 mg/dL.
• Impaired cardiac function as evidenced by symptoms consistent with New York Heart Association Classification Class 2 or worse.
• Received Renal Replacement Therapy (RRT) within 4 weeks of randomization.
• Has had a Trans Jugular Intrahepatic Porto-systemic shunt (TIPS).
• Pregnant or breastfeeding.
• Diagnosed with a malignancy within the past 5 years.
• History or current evidence of any condition (COVID-19 positive with respiratory/cardiac complications), therapy or laboratory abnormality that might confound the results of the study, interfere with the participation for the full duration of the study, or is not in the best interest to participate in the opinion of the investigator.
• Participated in a study of an investigational medical product or device within the last 8 weeks preceding screening.
• Experienced a major blood loss (≥500 mL) within the last 4 weeks prior to screening.
• Is stuporous or comatose at screening (West Haven scores III and IV). exhibiting bradycardia.
Drug: OCE-205, Drug: Placebo
Cirrhosis, Ascites, Hepatorenal Syndrome, Acute Kidney Injury
HRS-AKI
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Study Locations
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| Location | Contacts |
|---|---|
| Baylor University Dallas, Texas | Principal Investigator Robert Rahimi |
| Indiana University Hospital Indianapolis, Indiana | Principal Investigator Eric Orman |
| Keck Medical Center of USC Los Angeles, California | Principal Investigator Saro Khemichian |
| M Health Fairview University of Minnesota Medical Center Minneapolis, Minnesota | Principal Investigator Nicholas Lim |
| Massachusetts General Hospital Boston, Massachusetts | Principal Investigator Andrew Allegretti |
| Mayo Clinic Jacksonville, Florida | Principal Investigator Douglas Simonetto |
| Mayo Clinic - Phoenix Phoenix, Arizona | Principal Investigator Hugo Vargas |
| McGuire VA Medical Center Richmond, Virginia | Principal Investigator Jasmohan Bajaj |
| MedStar Georgetown University Hospital Washington D.C., District of Columbia | Principal Investigator Amol Rangnekar |
| New York-Presbyterian Hospital New York, New York | Principal Investigator Robert Brown |
| Northwestern Medicine Chicago, Illinois | Principal Investigator Daniel Ganger |
| Piedmont Atlanta Hospital Atlanta, Georgia | Principal Investigator: Lance Stein |
| Rutgers New Jersey Medical School Newark, New Jersey | Principal Investigator Nikolaos Pyrsopoulos |
| Tampa General Medical Group Tampa, Florida | Principal Investigator Nyingi Kemmer |
| Toronto General Hospital Toronto, | Principal Investigator Florence Wong |
| University of California, San Francisco Liver Clinic San Francisco, California | Principal Investigator Giuseppe Cullaro |
| University of Cincinnati Medical Center Cincinnati, Ohio | Principal Investigator Khurram Bari |
| University of Maryland Medical Center Baltimore, Maryland | Principal Investigator Kirti Shetty |
| University of Missouri Columbia, Missouri | Principal Investigator Syed Naqvi |
| Virginia Commonwealth University Health System Richmond, Virginia | Principal Investigator Arun Sanyal |
Intestinal Microbiota Transplant in Alcohol-Associated Liver Disease (IMPACT)
Jasmohan S Bajaj, MD - jasmohan.bajaj@vcuhealth.org
NCT05548452
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Inclusion Criteria:
-\>18 years of age
* Advanced liver disease
* Able to give written, informed consent
* Alcohol as a cause of advanced liver disease
* Continued sustained drinking
* Having previously declined a referral to traditional AUD therapy services or having failed such treatments
Exclusion Criteria:
* Lack of sustained drinking
* Recent or current alcoholic hepatitis
* Alcohol withdrawal symptoms
* Clinically significant use of illicit drugs
* Uncontrolled mood disorders or primary psychotic conditions
* MELD score\>17
* Unclear diagnosis of chronic liver disease
* Current hepatic encephalopathy on lactulose and/or rifaximin
* WBC count\<1000
* Non-elective hospitalization within last month
* on dialysis
* known untreated, in-situ luminal GI cancers
* chronic intrinsic GI diseases (ulcerative colitis, Crohn's disease or microscopic colitis, eosinophilic gastroenteritis and celiac disease)
* Dysphagia within 2 weeks
* History of aspiration, gastroparesis, intestinal obstruction
* Ongoing absorbable antibiotic use
* Severe anaphylactic food allergy
* allergy to ingredients Generally Recognized As Safe in the G3 capsules (glycerol, sodium chloride, hypromellose, gellan gum, titanium dioxide, theobroma oil)
* Adverse event attributable to prior IMT
* ASA Class IV or V
* Pregnant or nursing patients
* acute illness or fever on the day of planned FMT
* Immunosuppression
* Other conditions which make patients are poor candidate for this study per investigator judgement DRUG: Intestinal Microbiota Transplant (IMT) Capsules, DRUG: Placebo Capsules
Liver Disease, Alcohol-Related, Cirrhosis, Alcohol Use Disorder
Intestinal Microbiota Transplant, Alcohol Use Disorder, Cirrhosis, Chronic Liver Disease
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| Location | Contacts |
|---|---|
| Hunter Holmes McGuire VA Medical Center Richmond, Virginia | |
| Virginia Commonwealth University Richmond, Virginia |
A Study to Evaluate the Safety and Efficacy of CNTX-6970 in Subjects With Knee Osteoarthritis Pain.
Aderonke Pederson, MD - apederson@mgh.harvard.edu
NCT05025787
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A subject will be eligible for study participation if they meet all of the following
criteria:
• Individuals between 40 and 90 years of age (inclusive) at the time of the Screening Visit.
• Willing to use a mobile smart device during the study period. Individuals who do not have access to a mobile device will be provided with one for the duration of the study and trained in its use.
• Can understand the nature of the study and protocol requirements and is willing to comply with study drug administration requirements and discontinue prohibited concomitant medications.
• Radiography of both knees with a posterior-anterior, fixed-flexion view taken during the Screening visit. The Index knee must show evidence of chronic OA with a K-L Grading Scale of 1, 2, 3, or 4. Such evidence will be provided by a central reading of the radiography of both knees from an expert radiologist of the CCC of EPPIC-Net.
• Moderate to severe pain in the Index knee associated with OA and stable for a minimum of 6 months prior to Screening in the opinion of the investigator.
• Confirmation of OA of the index knee: American College of Rheumatology (ACR) diagnostic criteria.
• Subjects must have failed 2 or more prior therapies. Failure is deemed to be inadequate relief in the opinion of the investigator.
• Body mass index (BMI) of ≤ 40 kg/m2.
• Willing to refrain from illicit drug use during the study, and to have illicit drug testing at screening and at later time points. A subject will be excluded from the study if they meet any of the following criteria:
• Any form of joint replacement surgery, open surgery, or arthroscopic surgery of the index knee/knee joint with 12 months of Screening.
• Any painful condition(s) of the index knee due to disease other than OA. For example, periarticular or referred pain involving the index knee, or from joint disease other than OA associated with the index knee.
• Other chronic pain anywhere in the lower extremities (e.g. hips, legs, feet) that is equal or greater in intensity or impairment than index knee pain or that requires the use of analgesic medications. This includes radicular low back pain with radiation to the knee.
• Documented history of neuropathic arthropathy in the knee.
• Significant instability (e.g., cruciate ligament tear or rupture or previous repair) within the past 5 years or current misalignment (>10 degrees varus or valgus) of the index knee.
• Plans to have surgery, invasive procedures, or intra-articular (IA) injections of the index knee or procedure or surgery otherwise contraindicated for study participation while in the study. a. Concomitant Medications for Pain - i. Continuous use of one of the following medications prescribed for pain: tramadol, gabapentin, duloxetine, pregabalin, milnacipran, or tricyclic antidepressants that is:
• chronic for at least 12 weeks; and
• at a stable dose for at least 4 weeks before Screening ii. Intermittent use of opioids that is:
• ongoing for at least 4 weeks before Screening;
• at a frequency no more than 4 days/week; and
• not be taken within 24 hours of a study visit iii. As needed use of acetaminophen b. Concomitant Medications for Non-Pain Indications That May Impact Pain - i. Continuous use of medication for non-pain indications that are known to potentially impact pain, e.g. duloxetine for depression, that is at a stable dose for at least 12 weeks prior to Screening.
• Corticosteroid injection in the index knee within 90 days of Screening or during study participation.
• Received IA viscosupplementation (e.g., Synvisc®, Hyalgan®) within 90 days of Screening or any time during study participation.
• History of clearly documented allergic reaction to celecoxib (Celebrex®), or to sulfa drugs.
• Use of an investigational medication within 30 days of Screening, or 5 pharmacokinetic or pharmacodynamic half-lives (whichever is longer) or scheduled to receive such an agent while participating in the current study.
• Current therapy with any immunosuppressive therapy, including corticosteroids (>5 mg/day of prednisone).
• Individuals between 40 and 90 years of age (inclusive) at the time of the Screening Visit.
• Willing to use a mobile smart device during the study period. Individuals who do not have access to a mobile device will be provided with one for the duration of the study and trained in its use.
• Can understand the nature of the study and protocol requirements and is willing to comply with study drug administration requirements and discontinue prohibited concomitant medications.
• Radiography of both knees with a posterior-anterior, fixed-flexion view taken during the Screening visit. The Index knee must show evidence of chronic OA with a K-L Grading Scale of 1, 2, 3, or 4. Such evidence will be provided by a central reading of the radiography of both knees from an expert radiologist of the CCC of EPPIC-Net.
• Moderate to severe pain in the Index knee associated with OA and stable for a minimum of 6 months prior to Screening in the opinion of the investigator.
• Confirmation of OA of the index knee: American College of Rheumatology (ACR) diagnostic criteria.
• Subjects must have failed 2 or more prior therapies. Failure is deemed to be inadequate relief in the opinion of the investigator.
• Body mass index (BMI) of ≤ 40 kg/m2.
• Willing to refrain from illicit drug use during the study, and to have illicit drug testing at screening and at later time points. A subject will be excluded from the study if they meet any of the following criteria:
• Any form of joint replacement surgery, open surgery, or arthroscopic surgery of the index knee/knee joint with 12 months of Screening.
• Any painful condition(s) of the index knee due to disease other than OA. For example, periarticular or referred pain involving the index knee, or from joint disease other than OA associated with the index knee.
• Other chronic pain anywhere in the lower extremities (e.g. hips, legs, feet) that is equal or greater in intensity or impairment than index knee pain or that requires the use of analgesic medications. This includes radicular low back pain with radiation to the knee.
• Documented history of neuropathic arthropathy in the knee.
• Significant instability (e.g., cruciate ligament tear or rupture or previous repair) within the past 5 years or current misalignment (>10 degrees varus or valgus) of the index knee.
• Plans to have surgery, invasive procedures, or intra-articular (IA) injections of the index knee or procedure or surgery otherwise contraindicated for study participation while in the study. a. Concomitant Medications for Pain - i. Continuous use of one of the following medications prescribed for pain: tramadol, gabapentin, duloxetine, pregabalin, milnacipran, or tricyclic antidepressants that is:
• chronic for at least 12 weeks; and
• at a stable dose for at least 4 weeks before Screening ii. Intermittent use of opioids that is:
• ongoing for at least 4 weeks before Screening;
• at a frequency no more than 4 days/week; and
• not be taken within 24 hours of a study visit iii. As needed use of acetaminophen b. Concomitant Medications for Non-Pain Indications That May Impact Pain - i. Continuous use of medication for non-pain indications that are known to potentially impact pain, e.g. duloxetine for depression, that is at a stable dose for at least 12 weeks prior to Screening.
• Corticosteroid injection in the index knee within 90 days of Screening or during study participation.
• Received IA viscosupplementation (e.g., Synvisc®, Hyalgan®) within 90 days of Screening or any time during study participation.
• History of clearly documented allergic reaction to celecoxib (Celebrex®), or to sulfa drugs.
• Use of an investigational medication within 30 days of Screening, or 5 pharmacokinetic or pharmacodynamic half-lives (whichever is longer) or scheduled to receive such an agent while participating in the current study.
• Current therapy with any immunosuppressive therapy, including corticosteroids (>5 mg/day of prednisone).
Drug: Celecoxib, Drug: CNTX-6970, Drug: Placebo
Knee Osteoarthritis
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Study Locations
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| Location | Contacts |
|---|---|
| Center for Clinical Research Winston-Salem, North Carolina | Brooke Marsh - (bmarsh@ccrpain.com) |
| Duke University Durham, North Carolina | Erica Walker - (erica.walker@duke.edu) |
| Icahn School of Medicine at Mount Sinai New York, New York | Gabriella Cedillo - (gabriela.cedillo@mssm.edu) Shanna-Kay Griffiths - (shanna-kay.griffiths@mssm.edu) |
| Massachusetts General Hospital Boston, Massachusetts | Grace Mogren - (gmogren@mgh.harvard.edu) |
| Medical University of South Carolina Charleston, South Carolina | Georgia Mappin - (mappin@musc.edu) |
| New York University Langone Health New York, New York | Apoorva Patil - (apoorva.patil@nyulangone.org) |
| UTsouthwestern Medical Center Dallas, Texas | Hemangi Dhole, MPH, MS - (hemangi.dhole@utsouthwestern.edu) |
| University of California San Diego San Diego, California | Phirum Nguyen - (psnguyen@health.ucsd.edu) |
| University of California- Davis Sacramento, California | Gaby Zumarman - (gzumaran@ucdavis.edu) Julia Martin - (jyhmartin@ucdavis.edu) |
| University of Chicago Chicago, Illinois | Edward Fox - (efox1@bsd.uchicago.edu) |
| University of Florida Gainesville, Florida | Brandi Lattinville - (BLattinville@anest.ufl.edu) |
| University of North Carolina Chapel Hill Chapel Hill, North Carolina | Julie Titter - (julie_titter@med.unc.edu) |
| University of Pennsylvania Philadelphia, Pennsylvania | Ashley Cole - (ashley.cole@pennmedicine.upenn.edu) |
| University of Pittsburgh Pittsburgh, Pennsylvania | Maya Maurer - (Mam708@pitt.edu) |
| University of Rochester Rochester, New York | Rachel De Guzman - (Rachel_Deguzman@URMC.Rochester.edu) |
| University of Washington Seattle, Washington | Julia Dursi - (jdursi@uw.edu) |
| University of Wisconsin- Madison Madison, Wisconsin | Rachel Huard - (huard@wisc.edu) |
| Virginia Commonwealth University Richmond, Virginia | Melanie Morgan - (melanie.morgan@vcuhealth.org) |
| VitaMed Research, LLC Palm Desert, California | Janette Castleberry - (janette.c@vitamedresearch.com) Jacqueline Maree - (jacqueline@vitamedresearch.com) |
IO102-IO103 in Combination With Pembrolizumab Versus Pembrolizumab Alone in Advanced Melanoma (IOB-013 / KN-D18)
Eva Ehrnrooth Chief Medical Officer, MD, PhD - ee@iobiotech.com
NCT05155254
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Inclusion Criteria:
• Histologically or cytologically confirmed stage III (unresectable) or stage IV melanoma, as per American Joint Committee on Cancer 8th edition guidelines not amenable to local therapy
• Patients are treatment naive, that is, no previous systemic anticancer therapy for unresectable or metastatic melanoma. For clarification, the following patients are eligible:
• Patients with proto-oncogene B-Raf (BRAFV600) mutation-positive melanoma are eligible if treatment naive and without rapidly progressive disease as per investigator assessment.
• Patients who have received previous adjuvant and/or neoadjuvant therapy with targeted therapy or immune therapy are eligible if administered the last dose at least 6 months before inclusion in this trial (randomization), and if relapse did not occur during active treatment or within 6 months of treatment discontinuation.
• At least 1 measurable lesion (not a cutaneous lesion) according to response evaluation criteria for solid tumors (RECIST v1.1) and confirmed by IRC.
• Provision of archival (obtained within 3 months), or newly acquired biopsy tissue not previously irradiated, and blood at screening for biomarker assessments. Formalin-fixed, paraffin embedded (FFPE) tissue blocks are preferred to slides. Newly obtained biopsies are preferred to archived tissue.
Exclusion Criteria:
• Patients with known or suspected central nervous system (CNS) metastases or with the CNS as the only site of active disease are excluded with the following exception: • Patients with controlled (stable) brain metastases will be allowed to enroll (subject to baseline magnetic resonance imaging (MRI) confirmation). Controlled (stable) brain metastases are defined as those with no radiographic progression for at least 4 weeks after radiation and/or surgical treatment at the time of signed informed consent. Patients must have been off steroids for at least 2 weeks before signed informed consent and have no new or progressive neurological signs and symptoms.
• Patient has received previous radiotherapy within 2 weeks of start of trial treatment (visit 2). Patients must have recovered from all radiation-related toxicities, not require corticosteroids, and not have had radiation pneumonitis. A 1-week washout is permitted for palliative radiation (≤2 weeks of radiotherapy) to non-CNS disease.
• Patients with BRAFV600-positive disease who are experiencing rapidly progressing disease and/or have received standard first-line therapy with BRAF and/or MEK inhibitor for unresectable or metastatic disease. Other protocol defined inclusion/exclusion criteria may apply.
Drug: IO102-IO103, Drug: Pembrolizumab
Metastatic Melanoma, Unresectable Melanoma
Metastatic melanoma, Unresectable melanoma, Immunotherapy, Progression free survival, IO102-IO103, Pembrolizumab
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Show 100 locations
Study Locations
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| Location | Contacts |
|---|---|
| AMC Amsterdam, locatie VUMC Amsterdam, | Fons van den Eertwegh, MD - (vandeneertwegh@amsterdamumc.nl) |
| AZ Nikolaas Sint-Niklaas, Oost-Vlaanderen | Vibeke Kruse, MD - (Vibeke.Kruse@vitaz.be) |
| AZ Sint-Jan Brugge - Oostende AV - Campus Sint-Jan Brugge, | Alain Bols, MD - (alain.bols@azsintjan.be) |
| Aalborg University Hospital Aalborg, | Charlotte Haslund, MD - (cah@rn.dk) |
| Aarhus University Hospital Aarhus N, | Henrik Schmidt, MD - (henrschm@rm.dk) |
| Azienda Ospedaliera Universitaria Senese Policlinico Le Scotte Siena, | Michele Maio, Prof - (mmaiocro@gmail.com) |
| Ben-Gurion University of the Negev - Soroka University Medical Center - Soroka Clinical Research Center Beer Sheva, | Alexander Yakobson, MD - (Alexy@clalit.org.il) |
| Bor, -Nemikortani es Onkodermatologiai Klinika Pecs, | Rolland Gyulai, M.D. - (gyulai.rolland@pte.hu) |
| Border Medical Oncology Research Unit Albury, New South Wales | Craig Underhill, M.D. - (Craig.Underhill@bordermedonc.com.au) |
| CH Universitario de A Coruña (CHUAC) A Coruña, | Maria Q. Varela, M.D. - (maria.quindos.varela@sergas.es) |
| CHIREC Brussels, | Corinne Gregoire - (md.corinne.gregoire@gmail.com) |
| CUF Tejo Lisbon, | Ana Raimundo, MD - (anaraimundo@hotmail.com) |
| Cairns Hospital Cairns, Queensland | Megan Lyle, M.D. - (Megan.Lyle@health.qld.gov.au) |
| Cape Town Oncology Trials (Pty) Ltd. Cape Town, | Conrad Jacobs, M.D. - (conrad.jacobs@cancercare.co.za) |
| Centre Eugene Marquis Rennes, | Thierry Lesimple, M.D. - (t.lesimple@rennes.unicancer.fr) |
| Centre Hospitalier Lyon Sud Pierre BĂŠnite, | Stephane Dalle, M.D. - (stephane.dalle@chu-lyon.fr) |
| Centre Hospitalier Universitaire de Besançon Jean Minjoz Besancon, | Charlee Nardin, Dr. |
| Centre Hospitalier Universitaire de Bordeaux Hospital Saint Andre Bordeaux, | Caroline Dutriaux, M.D. - (caroline.dutriaux@chu-bordeaux.fr) |
| Centre Hospitalier Universitaire de Lille Lille, | Laurent Mortier, M.D. - (Laurent.MORTIER@CHRU-LILLE.FR) |
| Centre Hospitalier de Valence (CHV) Valence, | Florent Grange, M.D. - (fgrange@ch-valence.fr) |
| Charite Universitaetsmedizin Berlin Berlin, | Max Schlaak, M.D. - (max.schlaak@charite.de) |
| Christie Hospital NHS Trust Manchester, | Paul Lorigan, MD - (paul.lorigan@nhs.net) |
| Christie Hospital NHS Trust Manchester, | Avinash Gupta, MD - (Avinash.gupta@nhs.net) |
| Chu Grenoble - Hopital Albert Michallon La Tronche, | Marie Enquebecq, MD - (menquebecq@chu-grenoble.fr) |
| Clinica Universidad de Navarra Madrid, | EDUARDO CASTAÑON, MD - (ecastanon@unav.es) |
| Department of Dermatology University of Mainz Mainz, | Stephan Grabbe, MD - (stephan.grabbe@unimedizin-mainz.de) |
| Ege university Faculty of Medicine, T. Aktas Oncology Hospital, Bornova Bornova, | Saziye B Karaca, MD - (karacaburcak@hotmail.com) |
| Elbe Klinikum Buxtehude Hamburg, | Peter Mohr - (peter.mohr@elbekliniken.de) |
| Emek Medical Center Afula, Northern District | Gil Bar-Sela, MD - (gil_ba@clalit.org.il) |
| FN Ostrava Ostrava, | Yvetta Vantuchova, MD - (yvetta.vantuchova@fno.cz) |
| FNHK Klinika onkologie a radioterapie Hradec Králové, | Jindrich Kopecky, MD - (jindrich.kopecky@fnhk.cz) |
| FNKV Department of Dermatology Praha, | Monika Arenbergerova, MD - (arenbergerova@email.cz) |
| Fakultni nemocnice Olomouc Olomouc, | Bohuslav Melichar, MD - (bohuslav.melichar@fnol.cz) |
| Flinders Medical Centre Bedford PK, South Australia | Amitesh Roy - (Amitesh.Roy@sa.gov.au) |
| Gustave Roussy Villejuif, | Caroline Robert, M.D. - (Caroline.ROBERT@gustaveroussy.fr) |
| Guy's Hospital London, | Yin Wu, MD - (yin.wu@kcl.ac.uk) |
| Hadassah University Hospital Jerusalem, | Michal Lotem, MD - (mlotem@hadassah.org.il) |
| Herlev og Gentofte Hospital Hellerup, Capital Region | Inge M. Svane, M.D. - (inge.marie.svane@regionh.dk) |
| Hetenyi G Korhaz, Onkologiai Kozpont Szolnok, | Tibor Csoszi, M.D. - (dr.cstibor@freemail.hu) |
| Hopital Ambroise Boulogne Billancourt, | Philippe Saiag, Prof. |
| Hopital de la Timone Marseille, Cedex | Caroline Gaudy, Prof - (caroline.gaudy@ap-hm.fr) |
| Hospital Clinic i Provincial Barcelona, | Ana Maria A Fernandez, M.D. - (amarance@clinic.cat) |
| Hospital Garcia de Orta HGO EPE Almada, | Frederico Sanches, MD - (fsanches@hgo.min-saude.pt) |
| Hospital General Universitario Gregorio Marañon Madrid, | Ivan Marquez Rodas, MD - (ivanpantic@hotmail.com) |
| Hospital General Universitario de Valencia Valencia, | Alfonso Berrocal Jaime, MD - (berrocal.alf@gmail.com) |
| Hospital Regional Universitario de Malaga Málaga, | Miguel Berciano, MD - (migueberci@gmail.com) |
| Hospital Tubingen Tubingen, | Teresa Amaral, MD - (teresa.amaral@med.uni-tuebingen.de) |
| Hospital Universitari Germans Trias i Pujol HUGTP, ICO-Badalona Barcelona, | Jose Luis M. Mozo, MD - (jmanzano@iconcologia.net) |
| Hospital Universitari i Politécnic La Fe Valencia, | Roberto D. Beveridge, M.D. - (diaz_rob@gva.es) |
| Hospital Universitario Central de Asturias (HUCA) Oviedo, | Isabel Palacio Vazquez, MD - (isabel.palacio@sespa.es) |
| Hospital Universitario HM Sanchinarro Madrid, | Juan Francisco Rodriguez, M.D. - (jfrodriguez@hmhospitales.com) |
| Hospital Universitario Ramon y Cajal Madrid, | Ainara S. Rivas, M.D. - (ainarasoria@hotmail.com) |
| Hospital Universitario Virgen Macarena Seville, | Luis de la Cruz Merino, M.D. - (ldelacruzmerino@gmail.com) |
| Hospital Vall d'Hebron Barcelona, | Eva Munoz Cosuelo - (emunoz@vhio.net) |
| IRCCS Ospedale San Raffaele Milan, | Vanesa Gregorc, MD - (vanesa.gregorc@ircc.it) |
| Idi-Irccs Rome, | Paolo Marchetti, MD - (paolo.marchetti@uniroma1.it) |
| Institut de Cancerologie de l'Ouest Saint-Herblain, | Melanie Saint-Jean - (Melanie.SaintJean@ico.unicancer.fr) |
| Instituto Oncologico Dr. Rosell IOR - Hospital Universitari Quiron Dexeus Barcelona, | Maria Gonzalez-Cao, M.D. - (mgonzalezcao@oncorosell.com) |
| Instituto Portugus de Oncologia de Lisboa Francisco Gentil Lisboa, | Emanuel Gouveia, MD - (egouveia@ipolisboa.min-saude.pt) |
| Istituto Nazionale Tumori IRCCS Fondazione Pascale Naples, | Paolo Ascierto, MD - (paolo.ascierto@gmail.com) |
| LMU Muenchen Muenchen, | Lucie Heinzerling, MD - (lucie.heinzerling@med.uni-muenchen.de) |
| LUMC Leiden, | Ellen Kapiteijn, MD - (h.w.kapiteijn@lumc.nl) |
| Maria Sklodowska-Curie National Research Institute of Oncology Warsaw, Masovian | Piotr Rutkowski - (piotr.rutkowski@pib-nio.pl) |
| Mary Potter Oncology Centre Groenkloof Pretoria, | Cohen Graham, MD - (glcresearch@mpoc.co.za) |
| Mater Public Hospital Dublin, | John Mccaffrey, MD - (jmccaffrey@mater.ie) |
| Miguel Servet University Hospital Zaragoza, | Teresa Puertolas Hernandez, MD - (tjpuertolas@gmail.com) |
| Mühlenkreiskliniken AöR, University Hospital Ruhr University Bochum Campus Minden Minden, | Ralf Gutzmer, Prof. |
| Nationales Centrum fr Tumorerkrankungen NCT Heidelberg, | Jessica Hassel, M.D. - (Jessica.Hassel@med.uni-heidelberg.de) |
| Odense University Hospital Odense, | Lars Bastholt - (lars.bastholt@rsyd.dk) |
| Orlando Health Cancer Institute Orlando, Florida | Sajeve Thomas, MD - (sajeve.thomas@orlandohealth.com) |
| Orszagos Onkologiai Intezet Budapest, | Gabriella Liszkay, M.D. - (liszkay@oncol.hu) |
| Ospedale S. Maria della Misericordia Perugia, | Mario Mandala, Prof - (mario.mandala@unipg.it) |
| Oxford University Hospitals NHS Foundation Trust Oxford, | Miranda Payne, Dr - (miranda.payne@ouh.nhs.uk) |
| Peter MacCallum Cancer Centre PMCC - East Melbourne Melbourne, | Shahneen Sandhu, M.D. - (shahneen.sandhu@petermac.org) |
| Rabin Medical Center Petah Tikva, Petah Tikva | Daniel Hendler, MD - (Danielh@clalit.org.il) |
| Roswell Park Cancer Institute Buffalo, New York | Igor Puzanov, M.D. - (Igor.Puzanov@RoswellPark.org) |
| SLK-Kliniken Heilbronn GmbH Heilbronn, BW | Uwe Martens, M.D. - (uwe.martens@slk-kliniken.de) |
| Saint John's Cancer Institute Santa Monica, California | Kim Margolin, M.D. - (KIM.MARGOLIN@PROVIDENCE.ORG) |
| Southern Medical Day Care Centre Wollongong, New South Wales | Daniel Brungs, M.D./Prof. - (Daniel.Brungs@health.nsw.gov.au) |
| St. Josef Hospital - Ruhr-Universitt Bochum Bochum, | Thilo Gamblichler - (t.gambichler@klinikum-bochum.de) |
| Sunshine Coast University Hospital Birtinya, | Mary Azer, M.D. - (Mary.Azer@health.qld.gov.au) |
| Szpital Kliniczny im. Heliodora Święcickiego UM w Poznaniu Poznan, | Jacek Mackiewicz, MD - (jmackiewicz@ump.edu.pl) |
| Tel Aviv Sourasky Medical Center Tel Aviv, Tel Aviv | Mor Miodovnik, MD - (mormio@gmail.com) |
| The Chaim Sheba Medical Center - The Ella Lemelbaum Institute for Immuno-Oncology Tel Hashomer, | Ronnie Shapira-Frommer, MD - (ronnie.shapira@sheba.health.gov.il) |
| The Netherlands Cancer Institute Amsterdam, | Christian Blank, M.D. - (c.blank@nki.nl) |
| UMC Maastricht Maastricht, | Maureen Aarts, MD - (mjb.essers.aarts@mumc.nl) |
| Universitaetsklinikum Essen Essen, | Dirk Schadendorf, M.D. - (dirk.schadendorf@uk-essen.de) |
| Universitaetsklinikum Schleswig-Holstein Kiel, | Patrick Terheyden, MD - (Patrick.Terheyden@uksh.de) |
| Universitair Ziekenhuis Gent UZ Gent Gent, Oost-Vlaanderen | Celine Jacobs, M.D. - (celine.jacobs@uzgent.be) |
| Universitatsklinikum Augsburg Medizincampus Sued Augsburg, | Julia Welzel, MD - (Julia.welzel@uk-augsburg.de) |
| Universitatsmedizin Mannheim Dermatologie Mannheim, | Jochen Utikal, MD - (jochen.utikal@umm.de) |
| Universittsklinikum Wuerzburg Wuerzburg, | Bastian Schilling, MD - (schilling_b@ukw.de) |
| University Hospital Erlangen Erlangen, Bavaria | Carola Berking, MD - (carola.berking@uk-erlangen.de) |
| University Hospital Frankfurt Theodor-Stern-Kai Frankfurt, | Roland Kaufmann, MD - (kaufmann.klifo@kgu.de) |
| University Medical Center Utrecht Utrecht, | Karijn Suijkerbuijk, MD - (K.Suijkerbuijk@umcutrecht.nl) |
| University of Kentucky Markey Cancer Center Lexington, Kentucky | Yvonne Taul - (Yvonne.Taul@uky.edu) |
| VCU Massey Cancer Center Richmond, Virginia | Andrew Poklepovic - (andrew.poklepovic@vcuhealth.org) |
| Veneto Oncology Institute Padova, | Vanna C. Sileni, MD - (vanna.chiarion@iov.veneto.it) |
| Westmead Hospital Westmead, New South Wales | Matteo Carlino, M.D. - (matteo.carlino@sydney.edu.au) |
| mid Florida hematology and Oncology Center Orange City, Florida | Santosh Nair - (drsmnair@aorcorp.com) |
Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma (MelMarT-II)
Melanoma and Skin Cancer Trials Coordinator - melmart@masc.org.au
NCT03860883
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Inclusion Criteria:
Patients may be included in the study if they meet ALL of the following criteria:
• 1. Patients must have a Stage II primary invasive cutaneous melanoma (pT2b-pT4b, AJCC 8th edition) with Breslow thickness \>1.0mm to 2.0mm; \>2.0mm to 4.0mm or \>4.0mm with ulceration, or \>2.0mm to 4.0mm; or \>4.0mm without ulceration (Table 1) as determined by diagnostic biopsy (narrow excision, incision, shave or punch biopsy) and subsequent histopathological analysis.
• Must have a primary melanoma that is cutaneous (including head, neck, trunk, extremity, scalp, palm or sole).
• An uninterrupted 2cm margin must be technically feasible around biopsy scar or primary melanoma.
• 4. Surgical intervention (which refers to the staging -SLNB and WLE as these are both to be done on the same day) must be completed within 120 days of the original diagnosis. Surgical intervention must also be performed within 28 days of randomisation.
• Patients must be 18 years or older at time of consent.
• Patient must be able to give informed consent and comply with the treatment protocol and follow up plan.
• Life expectancy of at least 5 years from the time of diagnosis, not considering the melanoma in question, as determined by the PI.
• Patients must have an ECOG performance score between 0 and 1 at screening.
• A survivor of prior cancer is eligible provided that ALL of the following criteria are met and documented: * The patient has undergone potentially curative therapy for all prior malignancies, * There has been no evidence of recurrence of any prior malignancies for at least FIVE years (with the exception of successfully treated uterine/cervical or non-melanoma skin cancers (SCCs/BCCs) with no evidence of recurrence), and * The patient is deemed by their treating physician to be at low risk of recurrence from previous malignancies.
Exclusion Criteria:
Patients will be excluded from the study for ANY of the following reasons:
• Uncertain diagnosis of melanoma i.e., so-called 'melanocytic lesion of unknown malignant potential'.
• Patient has already undergone WLE at the site of the primary index lesion.
• Patient unable or ineligible to undergo staging SLNB of the primary index lesion.
• Perineural invasion or neurotropic melanoma: Neurotropism or perineural invasion in any type of melanoma is an exclusion. Perineural invasion does not include entrapment of nerves within the main primary tumour mass.
• Desmoplastic melanoma: with any patient where pathology determines melanoma as PURE desmoplastic (as per WHO definition of \>90% desmoplasia), they are not eligible for this study. However melanomas with less than 90% desmoplasia or mixed desmoplastic subtypes are eligible unless there is neurotropism present (perineural invasion).
• Microsatellitosis (a nest of metastatic tumour cells found to be growing away from the primary tumour) as per AJCC 8th edition definition is an exclusion.
• Subungual melanoma
• Patient has already undergone a local flap reconstruction of the defect after excision of the primary and determination of an accurate excision margin is impossible.
• History of previous or concurrent (i.e. \>1 primary melanoma) invasive melanoma.
• Melanoma located distal to the metacarpophalangeal joint; on the tip of the nose; the eyelids or on the ear; genitalia, perineum or anus; mucous membranes or internal viscera.
• Physical, clinical, radiographic or pathologic evidence of satellite, in-transit, regional, or distant metastatic melanoma.
• Patient has undergone surgery on a separate occasion to clear the lymph nodes of the probable draining lymphatic field, including -SLNB, of the index melanoma.
• Any additional solid tumour or hematologic malignancy during the past 5 years (with exception of non- melanoma skin cancers (T1 skin lesions of squamous cell carcinoma (SCCs), basal cell carcinoma (BCCs)), or uterine/cervical cancer).
• Melanoma-related operative procedures not corresponding to criteria described in the protocol.
• Planned adjuvant radiotherapy to the primary melanoma site after wide local excision is not permitted as part of the protocol and any patients given this treatment would be excluded from the study.
• History of organ transplantation.
• Oral or parenteral immunosuppressive agents (not topical or inhaled steroids) at enrolment or within 6 months prior to enrolment. Pregnancy is not a specific exclusion criterion for this trial, though it may not be clinically appropriate to perform a wide excision and SLNB until the pregnancy has been completed, which may exclude the patient due to violation of inclusion criterion 4. We would advise careful counselling of the patient prior to enrolling the patient, which would include a discussion at the treating centre's multidisciplinary team meeting or tumour board. We would strongly advise contacting the central trial office to discuss the case prior to enrolling on the study.
PROCEDURE: Wide Local Excision = 1cm Margin, PROCEDURE: Wide Local Excision = 2cm Margin
Cutaneous Melanoma, Stage II
Malignant, Melanoma, Cancer, Surgery
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Study Locations
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| Location | Contacts |
|---|---|
| AOU Città della Salute e della Scienza di Torino Torino, | |
| Advocate Illinois Masonic Medical Center Chicago, Illinois | Sigrun Hallmeyer - (sigrun.hallmeyer@aah.org) |
| Advocate Lutheran General Hospital Park Ridge, Illinois | Sigrun Hallmeyer, MD - (sigrun.hallmeyer@aah.org) Cheryl Korabik - (cheryl.korabik@aah.org) |
| Aurora St Luke's Medical Center Milwaukee, Wisconsin | Sigrun Hallmeyer - (sigrun.hallmeyer@aah.org) |
| BCCA - Cancer Centre for the Southern Interior Kelowna, British Columbia | Christopher Baliski - (cbaliski@bccancer.bc.ca) |
| Banner MD Anderson Cancer Center Gilbert, Arizona | Mark Gimbel - (mark.gimbel@bannerhealth.com) Sandra Ortega - (sandra.ortega@bannerhealth.com) |
| Baptist MD Anderson Cancer Center Jacksonville, Florida | Konstantinos Chouliaras - (Konstantinos.Chouliaras@bmcjax.com) |
| Calvary Public Hospital Bruce Bruce, Australian Capital Territory | |
| Cambridge University Hospitals NHS Foundation Trust Cambridge, | Amit Roshan - (amit.roshan@addenbrookes.nhs.uk) |
| CancerCare Manitoba Winnipeg, Manitoba | |
| Carilion Roanoke Memorial Hospital Roanoke, Virginia | Giao Phan - (giao.phan@vcuhealth.org) Kristin Campbell - (klcampbell@vcu.edu) |
| Central Hospital Kristianstad Kristianstad, | Dr Karolin Isaksson - (karolin.isaksson@med.lu.se) |
| Centre Hospitalier de L'Universite de Montreal (CHUM) Montreal, Quebec | |
| Cooperman Barnabas Medical Center West Orange, New Jersey | Adam Berger - (ab2047@cinj.rutgers.edu) |
| Cork University Hospital Cork, | |
| Cox South Hospital Springfield, Missouri | |
| Diakonessenhuis Utrecht, | |
| Duke University Medical Center Durham, North Carolina | Jay Lee - (jay.lee@duke.edu) |
| East Carolina University Greenville, North Carolina | Nasreen Vohra - (joynersu@ecu.edu) |
| Emory Saint Joseph's Hospital Atlanta, Georgia | Michael Lowe, MD - (mlowe3@emory.edu) Charisse Ellis - (chariesse.aliyya.ellis@emory.edu) |
| Emory University Atlanta, Georgia | |
| Emory University Hospital Midtown Atlanta, Georgia | Michael Lowe, MD - (mlowe3@emory.edu) Rachel Mock - (rachel.ashley.mock@emory.edu) |
| Flevo Hospital Almere, Flevoland | - (gdiepenhorst@flevoziekenhuis.nl) |
| Fondazione IRCCS Policlinico San Matteo Pavia, | |
| Fox Chase Cancer Center Philadelphia, Pennsylvania | |
| Franciscan Health Indianapolis Indianapolis, Indiana | Juliana Meyer - (juliana.meyer@franciscanalliance.org) |
| Gelre Hospital Zutphen, Gelderland | Dominique van Uden, MD - (d.van.uden@gerle.nl) |
| Guthrie Medical Group PC-Robert Packer Hospital Sayre, Pennsylvania | David Bertsch, MD - (david.j.bertsch@guthrie.org) Susan Hadlock - (susan.hadlock@guthrie.org) |
| Guy's and St Thomas's NHS Foundation Trust, of St Thomas' Hospital London, | Jenny Geh, Ms - (Jenny.Geh@gstt.nhs.uk) |
| Hamilton Health Sciences Centre Hamilton, Ontario | |
| Hopital Maisonneuve-Rosemont Québec, | |
| Hotel-Dieu de Quebec Québec City, Quebec | Dr Cindy Boulanger-Gobeil - (cindy.boulanger-gobeil@chudequebec.ca) |
| Hull University Teaching Hospitals NHS Trust Cottingham, | Paolo Matteucci - (paolo.matteucci@hey.nhs.uk) |
| Huntington Memorial Hospital Pasadena, California | Mark Faries - (mfaries@theangelesclinic.org) |
| Huntsman Cancer Institute (The University of Utah) Salt Lake City, Utah | |
| IOV Istituto Oncologico Veneto IRCCS-Padova Padova, | |
| Imperial College Healthcare NHS Trust London, | Jonathon Dunne - (jonathan.dunne1@nhs.net) Mark Cabelles - (mark.cabelles@nhs.net) |
| Indiana University - Melvin and Bren Simon Cancer Center Indianapolis, Indiana | - (karlb@iu.edu) |
| Indiana University Melvin and Bren Simon Comprehensive Cancer Center Indianapolis, Indiana | Karl Bilimoria - (karlb@iu.edu) |
| Institute of Oncology Ljubljana Ljubljana, | |
| Intermountain Medical Center Murray, Utah | Tawnya Bowles - (tawnya.bowles@imail.org) Kevin Adams - (Kevin.Adams@imail.org) |
| Isala Hospital Zwolle, | |
| Kaiser Permanente - Vallejo Medical Center Vallejo, California | Tatjana Kolevska, MD - (Tatjana.Kolevska@kp.org) Desiree Goldstein - (desiree.goldstein@kp.org) |
| Kaiser Permanente - Walnut Creek Medical Center Walnut Creek, California | Tatjana Kolevska, MD - (Tatjana.Kolevska@kp.org) Desiree Goldstein - (desiree.goldstein@kp.org) |
| Kaiser Permanente Northwest - Oncology Clinic Portland, Oregon | Sandeep Mashru - (sandeep.h.mashru@kp.org) |
| Kaiser Sunnyside Medical Center Clackamas, Oregon | Sandeep Mashru - (sandeep.h.mashru@kp.org) |
| Lakeland Regional Health Hollis Cancer Center Lakeland, Florida | Manuel Molina - (manuel.molina@mylrh.org) |
| Lancashire Teaching Hospitals NHS Foundation Trust Preston, Lancashire | Richard Wain - (richard.wain@lthtr.nhs.uk) |
| Laura & Isaac Perlmutter Cancer Center at NYU Langone Health New York, New York | Erica Friedman - (mailto:Erica.Friedman@nyulangone.org) |
| Los Angeles General Medical Center Los Angeles, California | Gino In - (gino.in@med.usc.edu) |
| Los Angeles General Medical Center Los Angeles, California | Gino In, MD - (gino.in@med.usc.edu) |
| Lovelace Medical Centre-Saint Joseph Square Albuquerque, New Mexico | Bridget Fahy, MD - (BFahy@salud.unm.edu) |
| Lovelace Women's Hospital Albuquerque, New Mexico | Bridget Fahy, MD - (BFahy@salud.unm.edu) |
| MID & South Essex NHS Foundation Trust Westcliff on Sea, Essex | Prof Peter Dziewulski - (peter.dziewulski1@nhs.net) |
| Maastricht University Medical Center Maastricht, | Kevin Wevers - (Kevin.wevers@mumc.nl) |
| Marshfield Medical Center - Marshfield Marshfield, Wisconsin | Rohit Sharma - (sharma.rohit@marshfieldclinic.org) |
| Marshfield Medical Center- Weston Weston, Wisconsin | Rohit Sharma, MD - (sharma.rohit@marshfieldclinic.org) |
| Mater Misericordiae University Hospital Dublin, Co Dublin | Shirley Potter - (shirleypott@gmail.com) |
| Maxima Medical Center - Veldhoven Veldhoven, | |
| Maxima Medical Centre, Eindhoven Eindhoven, Noord-Brabant | |
| Mayo Clinic Phoenix Phoenix, Arizona | Barbara A Pockaj, MD - (pockaj.barbara@mayo.edu) Courtney Nelson - (Nelson.Courtney4@mayo.edu) |
| Mayo Clinic in Florida Jacksonville, Florida | James W Jakub - (Jakub.James@mayo.edu) |
| MedStar Franklin Square Medical Center Rosedale, Maryland | Edward McCarron - (edward.mccarron@medstar.net) |
| MedStar Georgetown University Hospital Washington D.C., District of Columbia | Geoffrey T Gibney - (geofrey.t.gibney@gunet.georgetown.edu) |
| Medical College of Wisconsin Milwaukee, Wisconsin | Jennifer Bruening - (jbruening@mcw.edu) Chloe Papageorgio - (cpapageorgio@mcw.edu) |
| Medical University of South Carolina Charleston, South Carolina | Andrea Abbott - (abbottan@musc.edu) |
| Medstar Washington Hospital Center Washington D.C., District of Columbia | Marc Boisvert, MD - (Marc.E.Boisvert@medstar.net) Nicolas Rojas - (Nicolas.Rojas@medstar.net) |
| Melanoma Institute Australia Sydney, New South Wales | |
| Memorial Sloan Kettering Cancer Center New York, New York | |
| Mercy Health Center - Oncology Hematology Oklahoma City, Oklahoma | Christian Ellis, DO - (christian.ellis@mercy.net) Trisha Strubhar - (trisha.strubhar@mercy.net) |
| Mercy Health Saint Mary's Grand Rapids, Michigan | Kathleen Yost - (kyost@crcwm.org) Renee Porter - (renee.porter@crcwm.org) |
| Miami Valley Hospital South Centerville, Ohio | James Ouellette - (jrouellett@premierhealth.com) |
| Moffitt Cancer Center - McKinley Campus Tampa, Florida | Jonathan Zager - (Jonathan.zager@moffitt.org) |
| Moffitt Cancer Center, Magnolia Campus Tampa, Florida | Jonathan Zager - (Jonathan.zager@moffitt.org) |
| NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center New York, New York | Bret Taback - (bt2160@cumc.columbia.ed) |
| NYU Langone Medical Center (Winthrop Hospital) Mineola, New York | Erica Friedman - (mailto:Erica.Friedman@nyulangone.org) |
| Nancy N and JC Lewis Cancer & Research Pavilion St. Joseph's/Candler Savannah, Georgia | Yana Puckett, MD - (drpucketty@sjchs.org) Stephanie Reyes - (smiths1@sjchs.org) |
| Nebraska Medicine - Bellevue Bellevue, Nebraska | Bradley Reames - (bradley.reames@unmc.edu) |
| Nebraska Medicine-Village Pointe Omaha, Nebraska | Bradley Reames - (bradley.reames@unmc.edu) |
| Norfolk and Norwich University Hospital NHS Trust Norwich, | |
| North Bristol NHS Trust Bristol, | Ewan Wilson, Mr - (Ewan.Wilson@nbt.nhs.uk) |
| North Shore Hospital Auckland, | |
| Northern Westchester Hospital Mount Kisco, New York | Alan Kadison - (Akadison@northwell.edu) |
| Northside Hospital Atlanta Atlanta, Georgia | Nicole Kounalakis - (nicole.kounalakis@northside.com) |
| Northside Hospital Cancer Institute Atlanta, Georgia | |
| Northwell Health Imbert Cancer Center Bay Shore, New York | Alan Kadison, MD - (akadison@northwell.edu) Diane Delliliune - (DDellili@northwell.edu) |
| Northwell Health/Center for Advanced Medicine Lake Success, New York | Alan Kadison, MD - (akadison@northwell.edu) Alexa Amoroso - (aamoroso1@northwell.edu) |
| Northwestern Medicine Cancer Center Delnor Geneva, Illinois | Jeffrey Wayne - (jeffrey.wayne@nm.org) |
| Northwestern Medicine Cancer Center Kishwaukee DeKalb, Illinois | Jeffrey Wayne - (jeffrey.wayne@nm.org) |
| Northwestern Medicine Cancer Center Lake Forest Hospital Lake Forest, Illinois | Jeffrey Wayne - (jeffrey.wayne@nm.org) |
| Northwestern Medicine Cancer Center Warrenville Warrenville, Illinois | Jeffrey Wayne - (jeffrey.wayne@nm.org) |
| Northwestern University Chicago, Illinois | Jeffrey Wayne - (jeffrey.wayne@nm.org) |
| Nottingham University Hospitals, NHS Trust, Trust HQ, City Hospital Nottingham, | Mr Jonathon Pollock - (Jonathan.Pollock@nuh.nhs.uk) |
| OUHSC Stephenson Cancer Center Oklahoma City, Oklahoma | William Dooley - (William-Dooley@ouhsc.edu) |
| Oak Valley Health Markham, Ontario | Jennifer Zhirui Li - (enli@oakvalleyhealth.ca) |
| Ohio State University Comprehensive Cancer Center Columbus, Ohio | Joal Joal - (Joal.Beane@osumc.edu) |
| Ottawa Hospital Research Institute Ottawa, Ontario | Dr. Carolyn Nessim - (cnessim@toh.ca) |
| Oxford University Hospitals NHS Foundation Trust Oxford, | - (oliver.cassell@ouh.nhs.uk) |
| Peter MacCallum Cancer Centre Melbourne, Victoria | |
| Phelps Memorial Hospital Center Sleepy Hollow, New York | Alan Kadison - (akadison@northwell.edu) |
| Princess Alexandra Hospital Woolloongabba, Queensland | |
| Queen Victoria Hospital NHS Foundation Trust East Grinstead, West Sussex | Siva Kumar - (siva.kumar1@nhs.net) |
| Robina Hospital Gold Coast, Queensland | |
| Roswell Park Cancer Institute Buffalo, New York | Shalana O'Brien - (shalana.obrien@roswellpark.org) |
| Royal Adelaide Hospital Adelaide, South Australia | Robert Whitfield - (Robert.Whitfield@sa.gov.au) |
| Royal Cornwall Hospital NHS Trust Truro, Cornwall | Polly King - (polly.king1@nhs.net) |
| Royal Free London NHS Foundation Trust London, | Steven Hamilton - (stephenhamilton@nhs.net) |
| Royal Prince Alfred Hospital Camperdown, New South Wales | |
| Royal Victoria Regional Health Centre Barrie, Ontario | Kelly Cruise - (cruisek@rvh.on.ca) |
| Rutgers Cancer Institute of New Jersey New Brunswick, New Jersey | |
| Sahlgrenska University Hospital Gothenburg, | Roger Olofsson Bagge - (roger.olofsson.bagge@gu.se) |
| Sanford Broadway Medical Centre Fargo, North Dakota | Preston Steen - (preston.steen@sanfordhealth.org) |
| Sanford Cancer Center Oncology Clinic Sioux Falls, South Dakota | Daniel Almquist, MD - (daniel.almquist@sanfordhealth.org) |
| Sanford Roger Maris Cancer Centre Fargo, North Dakota | Preston Steen - (preston.steen@sanfordhealth.org) |
| Sanford USD Medical Center - Sioux Falls Sioux Falls, South Dakota | Daniel Almquist, MD - (daniel.almquist@sanfordhealth.org) |
| Siteman Cancer Centre, Barnes Jewish West County Creve Coeur, Missouri | Ryan Fields - (rcfields@wustl.edu) |
| Smilow Hospital Care Center, Guilford Guilford, Connecticut | James Clune - (james.clune@yale.edu) |
| South Tees Hospitals NHS Foundation Trust of The James Cook University Hospital Middlesbrough, | Oliver Bassett, Mr - (o.bassett@nhs.net) |
| Spectrum Health at Butterworth Campus Grand Rapids, Michigan | Kathleen Yost - (Kyost@chcwm.com) |
| St George's University Hospitals NHS Foundation Trust London, | Joy Odili, Ms - (Joy.Odili@stgeorges.nhs.uk) |
| St James Hospital Dublin, | Marlese Dempsey - (marlesedempsey@gmail.com) |
| St Luke's University Health Network Quakertown Campus Quakertown, Pennsylvania | Darius Desai - (Darius.Desai@sluhn.org) |
| St Luke's University Health Network, Anderson Campus Easton, Pennsylvania | Darius Desai - (Darius.Desai@sluhn.org) |
| St Luke's University Health Network, Bethlehem Campus Bethlehem, Pennsylvania | Darius Desai - (Darius.Desai@sluhn.org) |
| St. Helens & Knowsley Teaching Hospitals NHS Trust Liverpool, | Rowan Pritchard Jones, Prof - (Rowan.PritchardJones@sthk.nhs.uk) |
| St. Luke's University Health Network - Allentown Cancer Center Allentown, Pennsylvania | Darius Desai, MD - (Darius.Desai@sluhn.org) Amy Grossman - (Amy.Grossman@sluhn.org) |
| St. Luke's University Health Network - Upper Bucks Quakertown, Pennsylvania | Darius Desai, MD - (Darius.Desai@sluhn.org) Amy Grossman - (Amy.Grossman@sluhn.org) |
| Stanford Cancer Center South Bay San Jose, California | |
| Stanford Cancer Institute Palo Alto, California | Amanda Kirane, MD FACS - (akirane@stanford.edu) Patrick Yuan - (yuanp@stanford.edu) |
| State University of New York Upstate Medical Center-Community Campus Syracuse, New York | Daniel Thomas, MD - (ThomasDa@upstate.edu) Laine Abernathy - (abernatl@upstate.edu) |
| State University of New York Upstate Medical University Syracuse, New York | Daniel Thomas, MD - (ThomasDa@upstate.edu) Laine Abernathy - (abernatl@upstate.edu) |
| Sunnybrook Health Sciences Centre Toronto, Ontario | |
| The Alfred Hospital Melbourne, Victoria | |
| The Angeles (Cedars-Sinai Medical Center and its Affiliates) Los Angeles, California | |
| The Canberra Hospital Garran, Australian Capital Territory | |
| The Christie NHS Foundation Trust Manchester, | Deemesh Oudit - (deemesh.oudit@nhs.net) |
| The Leeds Teaching Hospitals NHS Trust Leeds, | Howard Peach, Mr - (h.peach@nhs.net) |
| The Royal Marsden Hospital NHS Foundation Trust London,, | Myles Smith - (Myles.Smith@rmh.nhs.uk) - (Myles.Smith@rmh.nhs.uk) |
| The University of Texas MD Anderson Cancer Center Houston, Texas | Jeffrey Gershenwald - (jgershen@mdanderson.org) |
| Tom Baker Cancer Centre Calgary, Alberta | |
| UC Irvine Health - Chao Family Comprehensive Cancer Center Orange, California | Jeremy Harris - (jpharris1@hs.uci.edu) |
| UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care Irvine, California | |
| UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care Irvine, California | Maki Yamamoto - (myamamot@hs.uci.edu) |
| UHN - Princess Margaret Cancer Centre Toronto, Ontario | Alexandra Easson, Dr - (Alexandra.Easson@uhn.ca) |
| USC Norris Comprehensive Cancer Center Los Angeles, California | Gino In - (gino.in@med.usc.edu) |
| USC Norris Comprehensive Cancer Center Los Angeles, California | Gino In, MD - (gino.in@med.usc.edu) |
| University Hospitals Avon Health Center Avon, Ohio | Luke Rothermel - (Luke.Rothermel@UHhospitals.org) |
| University Hospitals Birmingham NHS Foundation Trust Birmingham, | Agustin Martin-Clavijo - (Agustin.Martin-Clavijo@uhb.nhs.uk) |
| University Hospitals Chagrin Highlands Medical Centre Orange Village, Ohio | Luke Rothermel - (Luke.Rothermel@UHhospitals.org) |
| University Hospitals Cleveland Medical Centre Cleveland, Ohio | Luke Rothermel - (Luke.Rothermel@UHhospitals.org) |
| University Hospitals Geauga Medical Center Chardon, Ohio | Luke Rothermel - (Luke.Rothermel@UHhospitals.org) |
| University Hospitals St. John Medical Center Westlake, Ohio | Luke Rothermel - (Luke.Rothermel@UHhospitals.org) |
| University Medical Centre Groningen Groningen, | Barbara Leeuwen - (b.l.van.leeuwen@umcg.nl) |
| University of Arkansas for Medical Sciences Little Rock, Arkansas | Michail Mavros - (MMavros@uams.edu) |
| University of Cincinnati Cincinnati, Ohio | Jeffrey Sussman - (sussmaj@ucmail.uc.edu) |
| University of Kansas Cancer Center Kansas City, Kansas | Luke Selby - (lselby@kumc.edu) |
| University of Kansas Hospital - Indian Creek Campus Overland Park, Kansas | Luke Selby - (lselby@kumc.edu) |
| University of Kansas Hospital- Westwood Cancer Center Westwood, Kansas | Luke Selby - (lselby@kumc.edu) |
| University of Kentucky Lexington, Kentucky | Erin Burke - (erin.burke@uky.edu) |
| University of Miami Comprehensive Cancer Center at Kendall Miami, Florida | Jessica S Crystal - (jxc2521@med.miami.edu) |
| University of Miami Comprehensive Cancer Center at Plantation Plantation, Florida | Jessica S Crystal - (jxc2521@med.miami.edu) |
| University of Miami Miller School of Medicine-Sylvester Cancer Centre Miami, Florida | Jessica S Crystal - (jxc2521@med.miami.edu) |
| University of Miami Sylvester Cancer Center at Coral Springs Coral Springs, Florida | Jessica S Crystal - (jxc2521@med.miami.edu) |
| University of Miami Sylvester Comprehensive Cancer Center at Aventura Aventura, Florida | Jessica S Crystal - (jxc2521@med.miami.edu) |
| University of Miami Sylvester Comprehensive Cancer Center at Coral Gables Coral Gables, Florida | Jessica S Crystal - (jxc2521@med.miami.edu) |
| University of Miami Sylvester Comprehensive Center at Deerfield Beach Deerfield Beach, Florida | Jessica S Crystal - (jxc2521@med.miami.edu) |
| University of Miami Sylvester Comprehensive Center at Hollywood Hollywood, Florida | Jessica S Crystal - (jxc2521@med.miami.edu) |
| University of Michigan - Brighton Center for Specialty Care Brighton, Michigan | Christina Angeles - (angelesc@med.umich.edu) |
| University of Michigan Medical Center Ann Arbor, Michigan | Christina Angeles - (angelesc@med.umich.edu) |
| University of Nebraska Medicine Omaha, Nebraska | Bradley Reames - (bradley.reames@unmc.edu) |
| University of North Carolina Hospitals - Hillsborough Campus Hillsborough, North Carolina | David Ollila - (david_ollila@med.unc.edu) |
| University of North Carolina at Chapel Hill Chapel Hill, North Carolina | David W Ollila - (david_ollila@med.unc.edu) |
| University of Rochester Rochester, New York | Paul Barr - (paul_barr@urmc.rochester.edu) |
| University of South Alabama Mitchell Cancer Institute Mobile, Alabama | John H Howard, MD - (jhoward@health.southalabama.edu) Tiffany Fulford - (tfulford@health.southalabama.edu) |
| University of Texas Health Science Center at San Antonio San Antonio, Texas | Fedrico Tozzi, MD - (tozzi@uthscsa.edu) Samantha Bankston - (bankstonsm@uthscsa.edu) |
| University of Vermont Medical Center Burlington, Vermont | Jessica Cintolo-Gonzalez, MD - (jessica.cintolo-gonzalez@uvmhealth.org) Elizabeth Abrecht - (elizabeth.abrecht@uvmhealth.org) |
| University of Vermount and Sate Agricultural College Burlington, Vermont | Jessica Cintolo-Gonzalez, MD - (jessica.cintolo-gonzalez@uvmhealth.org) Elizabeth Abrecht - (elizabeth.abrecht@uvmhealth.org) |
| University of Virginia Health System Charlottesville, Virginia | Lynn Dengel - (LTD5B@uvahealth.org) |
| University of Winsconsin Carbone Cancer Center-Eastpark medical Center Madison, Wisconsin | Heather Neuman - (neuman@surgery.wisc.edu) Heather Neuman, MD - (neuman@surgery.wisc.edu) |
| University of Wisconsin Carbone Cancer Center Madison, Wisconsin | Heather Neuman - (neuman@surgery.wisc.edu) Sam Hanson - (shhanson@wisc.ed) |
| VCU Massey Cancer Center Richmond, Virginia | Giao Phan - (giao.phan@vcuhealth.org) |
| VCU Massey Cancer Center Affiliate Valley Health Winchester, Virginia | Giao Phan - (giao.phan@vcuhealth.org) |
| VCU Massey Cancer Center Peninsula Cancer Institute Newport News, Virginia | Giao Phan - (giao.phan@vcuhealth.org) |
| Vassar Brothers Medical Center Poughkeepsie, New York | James Nitzkorski - (james.nitzkorski@nuvancehealth.org) Karley Flinn - (karley.flinn@nuvancehealth.org) |
| Washington University School of Medicine St Louis, Missouri | Ryan Fields - (rcfields@wustl.edu) |
| West Chester Hospital (OH394) West Chester, Ohio | Jeffrey Sussman - (sussmaj@ucmail.uc.edu) |
| West Michigan Cancer Centre Kalamazoo, Michigan | Kathleen Yost - (kyost@chcwm.com) |
| Westmead Hospital Westmead, New South Wales | Pablo Fernandez-Peñas - (pablo.fernandezpenas@sydney.edu.au) |
| Wilmont Cancer Institute at Webster Webster, New York | Paul Barr, MD - (paul_barr@urmc.rochester.edu) Sarah Cawley - (sarah_cawley@urmc.rochester.edu) |
| Yale University New Haven, Connecticut | James Clune - (james.clune@yale.edu) |
| Ziekenhuis Gelderse Vallei Ede, Gelderland | Miriam L Hoven-Gondrie - (HovenM@zgv.nl) |
| Zuyderland Medical Center Sittard-Geleen, |
A Study of Comparing Talquetamab to Belantamab Mafodotin in Participants With Relapsed/Refractory Multiple Myeloma (MonumenTAL-5)
Study Contact - Participate-In-This-Study@its.jnj.com
NCT05461209
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Inclusion Criteria:
• Documented multiple myeloma as defined by the criteria: a) multiple myeloma according to international myeloma working group (IMWG) diagnostic criteria b) measurable disease at screening, as assessed by central laboratory, defined by any of the following i) serum M-protein level greater than or equal to (>=) 1.0 gram per deciliter (g/dL) ii) urine M-protein level >=200 milligram (mg)/24 hours iii) Light chain multiple myeloma without measurable M-protein in the serum or the urine: serum free light chain (sFLC) >=10 milligram per deciliter (mg/dL) (central laboratory) and abnormal serum immunoglobulin kappa lambda free light chain (FLC) ratio
• Received at least 4 prior antimyeloma therapies including an anti-cluster of differentiation 38 (CD38) monoclonal antibody (mAb) (alone or in combination) and is refractory per IMWG criteria to at least one proteasome inhibitor (PI), and one immunomodulatory drug (IMiD)
• Documented evidence of progressive disease based on investigator's determination of response by IMWG criteria on or after their last regimen
• Have an Eastern Cooperative Oncology Group (ECOG) performance status of 0 to 2 at screening
• A female participant of childbearing potential must have a negative serum pregnancy test at screening, and must agree to further serum or urine pregnancy tests during the study and within 6 months after receiving the last dose of study treatment
Exclusion Criteria:
• Contraindications or life-threatening known allergies, hypersensitivity, or intolerance to any study drug or its excipients
• Stroke or seizure within 6 months prior to signing informed consent form (ICF)
• Prior or concurrent exposure to belantamab mafodotin
• Current corneal epithelial disease except mild punctate keratopathy
• Known active central nervous system (CNS) involvement or exhibits clinical signs of meningeal involvement of multiple myeloma. If either is suspected, negative whole brain magnetic resonance imaging (MRI) and lumbar cytology are required
Drug: Talquetamab, Drug: Belantamab Mafodotin
Relapsed/ Refractory Multiple Myeloma
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See this study on ClinicalTrials.gov
Show 85 locations
Study Locations
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| Location | Contacts |
|---|---|
| A.O. Universitaria Senese- Ospedale Santa Maria alle Scotte Siena, | |
| ASST Sette Laghi, Ospedale di Circolo e Fondazione Macchi Varese, | |
| Alexandra General Hospital of Athens Athens Attica, | |
| Asst Ovest Milanese - Ospedale Di Legnano Legnano, | |
| Azienda Ospedaliera Universitaria Città della Salute e della Scienza di Torino Torino, | |
| Azienda Ospedaliera di Perugia Ospedale S.Maria della Misericordia Perugia, | |
| Azienda Ospedaliero Universitaria Policlinico Paolo Giaccone Palermo, | |
| Belfast City Hospital Belfast, | |
| Beth Israel Deaconess Medical Center Boston, Massachusetts | |
| CHU de Québec Université Laval Quebec, | |
| CIUSSS de l'Est-de-l'Île-de-Montréal Installation Hôpital Maisonneuve-Rosemont Montreal, Quebec | |
| Carmel Medical Center Haifa, Haifa District | |
| Centro Hospitalar Vila Nova de Gaia Vila Nova de Gaia, | |
| Champalimaud Foundation Champalimaud Centre Lisbon, | |
| Derriford Hospital Plymouth, | |
| Fakultni Nemocnice Ostrava Ostrava, | |
| Fakultni nemocnice Brno Brno, | |
| Fakultni nemocnice Hradec Kralove Hradec Králové, | |
| Fakultni nemocnice Olomouc Olomouc, | |
| Fondazione IRCCS Cà Granda, Ospedale Policlinico di Milano Milano, | |
| Fondazione IRCCS Istituto Nazionale dei Tumori Milan, | |
| Fondazione IRCCS Policlinico San Matteo Pavia, | |
| Highlands Oncology Group Fayetteville, Arkansas | |
| Hosp. Clinic I Provincial de Barcelona Barcelona, | |
| Hosp. Garcia de Orta Almada, | |
| Hosp. Gral. Univ. Gregorio Marañon Madrid, | |
| Hosp. Gral. Univ. de Toledo Toledo, | |
| Hosp. Quiron Madrid Pozuelo Pozuelo de Alarcón, | |
| Hosp. Univ. Dr. Peset Valencia, | |
| Hosp. Univ. Germans Trias I Pujol Badalona, | |
| Hosp. Univ. Marques de Valdecilla Santander, | |
| Hosp. Univ. Vall D Hebron Barcelona, | |
| Hosp. Univ. Virgen de La Arrixaca El Palmar, | |
| Hosp. Univ. de La Princesa Madrid, | |
| Hosp. de Cabuenes Asturias, | |
| Hosp. de Leon León, | |
| Hospital Santa Maria della Misericordia Udine, | |
| Huntsman Cancer Institute Salt Lake City, Utah | |
| Instituto Portugues de Oncologia Porto, | |
| Instituto Portugues de Oncologia Porto, | |
| Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori Meldola, Forli-cesena | |
| Karmanos Cancer Institute Detroit, Michigan | |
| Klinikum rechts der Isar der TU Muenchen Munich, Bavaria | |
| Mayo Clinic Jacksonville, Florida | |
| Mayo Clinic Rochester Rochester, Minnesota | |
| MedStar Georgetown University Hospital Washington D.C., District of Columbia | |
| Medical College of Wisconsin Milwaukee, Wisconsin | |
| Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - Panstwowy Instytut Badawczy Warszawa, | |
| New Cross Hospital Wolverhampton, | |
| New Jersey Hematology Oncology Ass. Brick, New Jersey | |
| Norwalk Hospital-oncology Norwalk, Connecticut | |
| Nottingham University Hospitals Nottingham, | |
| Nova Scotia Health Authority Sydney, Nova Scotia | |
| Novant Health Charlotte, North Carolina | |
| Novant Health Charlotte, North Carolina | |
| Ochsner Medical Center New Orleans, Louisiana | |
| Policlinico Sant'Orsola Malpighi Bologna, | |
| Queen Alexandra Hospital Portsmouth, | |
| Rabin Medical Center Petah Tikva, Petah Tikva | |
| Rambam Medical Center Haifa, Haifa District | |
| Royal Marsden Hospital Sutton, | |
| Saint Luke's Hospital - Saint Luke's Cancer Specialists Chesterfield, Missouri | |
| Sheba Medical Center Ramat Gan, Ramat Gan | |
| Swietokrzyskie Centrum Onkologii SPZOZ w Kielcach Kielce, | |
| Szpital Kliniczny im. H. Swiecickiego Uniwersytetu Medycznego im. K. Marcinkowskiego w Poznaniu Poznań, | |
| Szpital Specjalistyczny w Brzozowie Podkarpacki Osrodek Onkologiczny im. Ks. B. Markiewicza Brzozow, | |
| Tulane University Hospital & Clinics New Orleans, Louisiana | |
| Universitaetsklinikum Frankfurt Frankfurt, | |
| Universitaetsklinikum Halle (Saale) Halle (Saale), | |
| Universitaetsklinikum Koeln Cologne, | |
| Universitaetsklinikum Schleswig-Holstein Campus Kiel Kiel, Schleswig-Holstein | |
| Universitaetsklinikum Tuebingen der Eberhard-Karls-Universitaet, Abteilung fuer Innere Medizin II, Tübingen, | |
| Universitaetsklinikum Wuerzburg Würzburg, | |
| University Health Network Toronto, Ontario | |
| University Hospital of Cleveland Cleveland, Ohio | |
| University of Arizona Cancer Center Tucson, Arizona | |
| University of Arkansas for Medical Sciences Little Rock, Arkansas | |
| University of California, San Francisco San Francisco, California | |
| University of Illinois Chicago, Illinois | |
| University of Pennsylvania Philadelphia, Pennsylvania | |
| University of Texas Southwestern Medical Center Dallas, Texas | |
| University of Wisconsin Carbone Cancer Center Madison, Wisconsin | |
| Uniwersytecki Szpital Kliniczny im. Jana Mikulicza-Radeckiego we Wroclawiu Wroclaw, | |
| Virginia Commonwealth University - Massey Cancer Center Richmond, Virginia | |
| Walter Reed National Military Medical Center Bethesda, Maryland |