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Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas

Contact(s):

ctrrecruit@vcu.edu

Principal Investigator:

System ID: NCT02523014

Show full eligibility criteria

* Documentation of disease: * Histologic documentation: histologically proven intracranial meningioma as documented by central pathology review * Molecular documentation: Presence of SMO, PTCH1, NF2, CDKN2A, AKT1, PIK3CA, PTEN mutations, CDKN2A copy number loss, CDK4, CDK6, CCND1, CCND2, CCND3, or CCNE1 copy number gain in tumor sample as documented specifically by the central laboratory, regardless of whether prior genotype testing outside of the central laboratory was performed * Progressive OR residual disease, as defined by the following: * Residual measurable disease: residual measurable disease immediately after surgery without requirement for progression; for grade I disease, progression pre-operatively needs to be documented, with an increase in size of the measurable primary lesion on imaging by 25% or more (bidirectional area); the change must occur between scans separated by no more than 25 months; for patients with SMO/PTCH1 mutations enrolling to receive vismodegib, the change can occur between scans separated by up to 25 months; residual measurable disease will be defined by bidimensionally measurable lesions with clearly defined margins by MRI scans, with a minimum diameter of 10 mm in both dimensions * Progressive measurable disease: progression defined as an increase in size of the measurable primary lesion on imaging by 25% or more (bidirectional area); the change must occur between scans separated by no more than 25 months * Post radiation patients: patients with measurable and progressive meningioma who have received radiation are potentially eligible, but need to show evidence of progressive disease after completion of radiation; if the progressive meningioma lesion has been radiated, at least 24 weeks must have elapsed from completion of radiation to registration; if the progressive lesion is outside of the radiation field, then an interval of at least 2 weeks must have elapsed from completion of radiation to registration * Measurable disease: measurable disease is defined by a bidimensionally measurable main lesion on MRI or computed tomography (CT) images (MRI preferred) with clearly defined margins and a minimum diameter of 10 mm in both dimensions; multifocal disease is allowed * Prior treatment * Prior medical therapy is allowed but not required * No limit on number of prior therapies * No chemotherapy, or other investigational agents within 28 days prior to registration * No other concurrent investigational agents or other meningioma-directed therapy (chemotherapy, radiation) while on study; additionally, no cases of nitrosourea or mitomycin C within 6 weeks prior to registration * For patients treated with external beam radiation, interstitial brachytherapy or radiosurgery, an interval \> 4 weeks must have elapsed from completion of radiation therapy to registration; if the progressive lesion is outside of the radiation field, then an interval of at least 2 weeks must have elapsed from completion of radiation to registration * Steroid dosing stable for at least 4 days * Recovered to Common Terminology Criteria for Adverse Events (CTCAE) grade 1 or less toxicity from other agents with exception of alopecia and fatigue * No craniotomy 28 days prior to and after registration * Not pregnant and not nursing: \* A female of childbearing potential is a sexually mature female who: 1) has not undergone a hysterectomy or bilateral oophorectomy; or 2) has not been naturally postmenopausal for at least 12 consecutive months (i.e., has had menses at any time in the preceding 12 consecutive months) * For patients with NF2/CDKN2A/AKT1/PIK3CA/PTEN mutation, CKDN2A copy number loss, or CDK4/CDK6/CCND1/CCND2/CCND3/CCNE1 copy number gain: Age \>= 18 years * For patients with SMO/PTCH1 mutation: Age \>= 30 years * Eastern Cooperative Oncology Group (ECOG) performance status =\< 2 * Patient history: * Patients with history of neurofibromatosis (NF) may have other stable central nervous system (CNS) tumors (schwannoma, acoustic neuroma or ependymoma) if lesions have been stable for 6 months * No metastatic meningiomas (as defined by extracranial meningiomas outside of CNS) allowed; spinal meningiomas are allowed * No history of allergic reactions attributed to compounds of similar or biologic composition to assigned study drug * No known active hepatitis B or C * No current Child Pugh class B or C liver disease * No uncontrolled gastric ulcer disease (grade 3 gastric ulcer disease within 28 days of registration) * No uncontrolled hypertension defined as blood pressure (BP) \> 140/90 * No abdominal fistula, gastrointestinal (GI) perforation, or intra-abdominal abscess within 28 days prior to registration * No major surgery within 28 days prior to registration for any patients with AKT1/PIK3CA/PTEN mutations receiving capivasertib * For patients going on to receive capivasertib (i.e. enrolled after Update #08) * Patients should not have any of the following cardiac criteria: * Any clinically important abnormalities in rhythm, conduction, or morphology of resting electrocardiogram (EKG) (e.g., complete left bundle branch block, third degree heart block) * Any factors that increase the risk of corrected QT (QTc) prolongation or risk of arrhythmic events such as heart failure, hypokalemia, potential for Torsade de Pointes, congenital long QT syndrome, family history of long QT syndrome, or unexplained sudden death under 40 years of age, or any concomitant medication known to prolong the QT interval * Experience any of the following procedures or conditions in the preceding 6 months: coronary artery bypass graft, angioplasty, vascular stent, myocardial infarction, angina pectoris, congestive heart failure New York Heart Association (NYHA) class \>= II * Uncontrolled hypertension (systolic blood pressure \[SBP\] \< 90 mmHg and/or diastolic blood pressure \[DBP\] \< 50 mmHg) * Cardiac ejection fraction outside institutional range of normal or \< 50% (whichever is higher) as measured by echocardiogram (or multigated acquisition \[MUGA\] scan if an echocardiogram can't be performed or is inconclusive); left ventricular ejection fraction (LVEF) below lower limit of normal for site * Patients should not have any of the following criteria: * With the exception of alopecia, any unresolved toxicities from prior therapy greater than Common Terminology Criteria for Adverse Events (CTCAE) grade 1 at the time of registration * Hemoglobin \< 9 g/dL (\< 5.59 mmol/L); note: any blood transfusion must be \>= 14 days prior to the determination of a hemoglobin \>= 9 g/dL (\>= 5.59 mmol/L) * Proteinuria 3+ on dipstick analysis or \> 500 mg/24 hours * Refractory nausea and vomiting, chronic gastrointestinal diseases, inability to swallow the formulated product or previous significant bowel resection that would preclude adequate absorption of capivasertib * History of hypersensitivity to active or inactive excipients of capivasertib or drugs with a similar chemical structure or class to capivasertib * Current disease or condition known to interfere with absorption, distribution, metabolism, or excretion of drugs * Past medical history of interstitial lung disease, drug-induced interstitial lung disease, radiation pneumonitis which required steroid treatment, or any evidence of clinically active interstitial lung disease * Previous allogeneic bone marrow transplant * Known immunodeficiency syndrome * Concomitant medications (only regarding NF2/CDKN2A/CDK4/CDK6/CCND1/CCND2/CCND3/CCNE1/AKT1/PIK3CA/PTEN genetic alterations): * Chronic concomitant treatment with strong inhibitors of cytochrome P450, family 3, subfamily A, polypeptide 4 (CYP3A4) inhibitors must discontinue the drug for 14 days prior to registration on the study for patients with NF2 mutation enrolled to GSK2256098, as well as for patients with AKT1/PIK3CA/PTEN mutations enrolled to capivasertib * For NF2 patients going on to receive GSK2256098 and for patients with AKT1/PIK3CA/PTEN mutations enrolled to capivasertib: concomitant treatment with strong CYP3A4 inducers or CYP2D6 substrates is not allowed; patients must discontinue the drug 14 days prior to registration * For NF2 patients going on to receive abemaciclib: avoid concomitant use of CYP3A inducers and strong CYP3A inhibitors; use caution with coadministered moderate or weak CYP3A inhibitors * Diabetic status: * For patients with NF2 or SMO/PTCH1 mutations: No uncontrolled diabetes defined as a known diabetic with HBA1C \> 7.5 OR fasting glucose \> 140 mg/dL. * For patients with AKT1/PIK3CA/PTEN mutations: * Glycosylated hemoglobin (HbA1C) \< 8.0% (63.9 mmol/mol) * No type 1 diabetes mellitus * No requirement for insulin for routine diabetic management and control * No requirement for more than two oral hypoglycemic medications for routine diabetic management and control * Patients with a pre-existing diagnosis of type 2 diabetes mellitus must have fasting glucose \< 9.3 mmol/L (167mg/dL); fasting is defined as no caloric intake for at least 8 hours * Patients without a pre-existing diagnosis of type 2 diabetes mellitus must have fasting glucose =\< 7.0 mmol/L (126 mg/dL); fasting is defined as no caloric intake for at least 8 hours * Absolute neutrophil count (ANC) \>= 1,500/mm\^3 * Platelet count \>= 100,000/mm\^3 * Creatinine OR =\< 1.5 mg/dl x upper limit of normal (ULN) OR calculated (calc.) creatinine clearance \> 50 mL/min * Urine protein:creatinine ratio (UPC) =\< 45 mg/mmol * Total bilirubin =\< 1.5 x upper limit of normal (ULN); except in case of Gilbert's disease * Aspartate aminotransferase (AST)/alanine aminotransferase (ALT) =\< 2.5 x ULN * Sodium, potassium, total calcium (corrected for serum albumin) \& phosphorus within normal limits per institutional guidelines * QTcF \< 450 msec (QT calculated using Fridericia formula) * Mean resting heart rate (determined from EKG) 50-100 beats per minute (BMP) (must be obtained from 12-lead EKG defined by a triplicate EKG for patients assigned to the capivasertib arm; patients assigned to all other arms will require a single EKG * No uncontrolled medical comorbidities per investigator discretion (e.g. interstitial lung disease, severe dyspnea at rest or requiring oxygen therapy, history of major surgical resection involving the stomach or small bowel, or pre-existing Crohn's disease or ulcerative colitis or a preexisting chronic condition resulting in baseline Grade 2 or higher diarrhea) * ADDITIONAL REGISTRATION ELIGIBILITY CRITERIA FOR ABEMACICLIB ARM: Hemoglobin \>= 8 g/dL \* Patients may receive erythrocyte transfusions to achieve this hemoglobin level at the discretion of the investigator; initial treatment must not begin earlier than the day after the erythrocyte transfusion * ADDITIONAL REGISTRATION ELIGIBILITY CRITERIA FOR ABEMACICLIB ARM: Prior Treatment * Patients who received chemotherapy must have recovered (Common Terminology Criteria for Adverse Events \[CTCAE\] grade =\< 1) from the acute effects of chemotherapy except for residual alopecia or grade 2 peripheral neuropathy prior to registration; a washout period of at least 28 days is required between last chemotherapy dose and registration (provided the patient did not receive radiotherapy) * Patients who received adjuvant radiotherapy must have completed and fully recovered from the acute effects of radiotherapy; a washout period of at least 28 days is required between end of radiotherapy and registration * ADDITIONAL REGISTRATION ELIGIBILITY CRITERIA FOR ABEMACICLIB ARM: No active bacterial infection (requiring intravenous \[IV\] antibiotics at time of initiating study treatment), fungal infection, or detectable viral infection (such as known human immunodeficiency virus positivity or with known active hepatitis B or C \[for example, hepatitis B surface antigen positive\]); screening is not required for enrollment in the absence of symptoms * ADDITIONAL REGISTRATION ELIGIBILITY CRITERIA FOR ABEMACICLIB ARM: No personal history of any of the following conditions: syncope of cardiovascular etiology, ventricular arrhythmia of pathological origin (including, but not limited to, ventricular tachycardia and ventricular fibrillation), or sudden cardiac arrest

Interventions: DRUG: Vismodegib, DRUG: FAK Inhibitor GSK2256098, DRUG: Capivasertib, DRUG: Abemaciclib

Conditions: Intracranial Meningioma, Recurrent Meningioma, NF2 Gene Mutation

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AMG Crystal Lake - Oncology Crystal Lake, Illinois	Site Public Contact - (advocateresearch@advocate.com)
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Advanced Breast Care Center PLLC Warren, Michigan
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Advocate High Tech Medical Park Palos Heights, Illinois	Site Public Contact - (ncorp@aah.org)
Advocate Illinois Masonic Medical Center Chicago, Illinois
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Advocate Outpatient Center - Oak Lawn Oak Lawn, Illinois	Site Public Contact - (ncorp@aah.org)
Advocate Sherman Hospital Elgin, Illinois
Advocate South Suburban Hospital Hazel Crest, Illinois
Alaska Breast Care and Surgery LLC Anchorage, Alaska	Site Public Contact - (AKPAMC.OncologyResearchSupport@providence.org)
Alaska Oncology and Hematology LLC Anchorage, Alaska	Site Public Contact - (AKPAMC.OncologyResearchSupport@providence.org)
Alaska Women's Cancer Care Anchorage, Alaska	Site Public Contact - (AKPAMC.OncologyResearchSupport@providence.org)
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Alliance for Childhood Diseases/Cure 4 the Kids Foundation Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
Alta Bates Summit Medical Center-Herrick Campus Berkeley, California
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Henry Ford Cancer Institute-Downriver Brownstown, Michigan
Henry Ford Health Saint John Hospital Detroit, Michigan	Site Public Contact - (Kkeenan1@hfhs.org)
Henry Ford Health Warren Hospital Warren, Michigan	Site Public Contact - (kforman1@hfhs.org)
Henry Ford Hospital Detroit, Michigan	Site Public Contact - (CTOResearch@hfhs.org)
Henry Ford Macomb Health Center - Shelby Township Shelby, Michigan
Henry Ford Macomb Hospital-Clinton Township Clinton Township, Michigan	Site Public Contact - (CTOResearch@hfhs.org)
Henry Ford Madison Heights Hospital - Breast Warren, Michigan	Site Public Contact - (kforman1@hfhs.org)
Henry Ford Medical Center-Columbus Novi, Michigan	Site Public Contact - (CTOResearch@hfhs.org)
Henry Ford Medical Center-Fairlane Dearborn, Michigan
Henry Ford River District Hospital East China Township, Michigan	Site Public Contact - (kforman1@hfhs.org)
Henry Ford Rochester Hospital Rochester Hills, Michigan
Henry Ford Saint John Hospital - Academic Grosse Pointe Woods, Michigan	Site Public Contact - (kforman1@hfhs.org)
Henry Ford Saint John Hospital - Breast Grosse Pointe Woods, Michigan	Site Public Contact - (karen.forman@ascension.org)
Henry Ford Saint John Hospital - Macomb Medical Macomb, Michigan	Site Public Contact - (kforman1@hfhs.org)
Henry Ford Saint John Hospital - Van Elslander Grosse Pointe Woods, Michigan	Site Public Contact - (kforman1@hfhs.org)
Henry Ford Warren Hospital - Breast Macomb Macomb, Michigan	Site Public Contact - (kforman1@hfhs.org)
Henry Ford Warren Hospital - GLCMS Warren, Michigan	Site Public Contact - (kforman1@hfhs.org)
Henry Ford West Bloomfield Hospital West Bloomfield, Michigan	Site Public Contact - (CTOResearch@hfhs.org)
Hi-Line Sletten Cancer Center Havre, Montana	Site Public Contact - (protocols@AllianceNCTN.org)
Highline Medical Center-Main Campus Burien, Washington
Holy Cross Hospital Fort Lauderdale, Florida	Site Public Contact - (eileen.georgi@holy-cross.com)
Hope Cancer Care of Nevada Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
Hope Cancer Care of Nevada-Pahrump Pahrump, Nevada	Site Public Contact - (research@sncrf.org)
Hope Cancer Center Pontiac, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
Hope Cancer Clinic Livonia, Michigan
Huntsman Cancer Institute/University of Utah Salt Lake City, Utah	Site Public Contact - (cancerinfo@hci.utah.edu)
Hurley Medical Center Flint, Michigan	Site Public Contact - (wstrong@ghci.org)
Huron Gastroenterology PC Ypsilanti, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
Idaho Urologic Institute-Meridian Meridian, Idaho	Site Public Contact - (stephanie.couch@stjoeshealth.org)
Illinois CancerCare - Washington Washington, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Bloomington Bloomington, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Canton Canton, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Carthage Carthage, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Dixon Dixon, Illinois
Illinois CancerCare-Eureka Eureka, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Galesburg Galesburg, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Kewanee Clinic Kewanee, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Macomb Macomb, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Ottawa Clinic Ottawa, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Pekin Pekin, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Peoria Peoria, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Peru Peru, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Princeton Princeton, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Indu and Raj Soin Medical Center Beavercreek, Ohio
Inova Fairfax Hospital Falls Church, Virginia
Inova Schar Cancer Institute Fairfax, Virginia	Site Public Contact - (Stephanie.VanBebber@inova.org)
Jersey Shore Medical Center Neptune City, New Jersey
Jewish Hospital Louisville, Kentucky
Jewish Hospital Medical Center South Shepherdsville, Kentucky
Johns Hopkins University/Sidney Kimmel Cancer Center Baltimore, Maryland	Site Public Contact - (jhcccro@jhmi.edu)
Kadlec Clinic Hematology and Oncology Kennewick, Washington	Site Public Contact - (research@kadlecmed.org)
Kaiser Permanente Los Angeles Medical Center Los Angeles, California	Site Public Contact - (clinical.trials@kp.org)
Kaiser Permanente Medical Center - Santa Clara Santa Clara, California
Kaiser Permanente Medical Center-Vacaville Vacaville, California
Kaiser Permanente Moanalua Medical Center Honolulu, Hawaii
Kaiser Permanente Sacramento Medical Center Sacramento, California
Kaiser Permanente San Leandro San Leandro, California
Kaiser Permanente Washington Seattle, Washington
Kaiser Permanente-Deer Valley Medical Center Antioch, California
Kaiser Permanente-Fremont Fremont, California
Kaiser Permanente-Fresno Fresno, California
Kaiser Permanente-Modesto Modesto, California
Kaiser Permanente-Oakland Oakland, California
Kaiser Permanente-Redwood City Redwood City, California
Kaiser Permanente-Richmond Richmond, California
Kaiser Permanente-Roseville Roseville, California
Kaiser Permanente-San Francisco San Francisco, California
Kaiser Permanente-San Rafael San Rafael, California
Kaiser Permanente-Santa Rosa Santa Rosa, California
Kaiser Permanente-Santa Teresa-San Jose San Jose, California
Kaiser Permanente-South Sacramento Sacramento, California
Kaiser Permanente-South San Francisco South San Francisco, California
Kaiser Permanente-Stockton Stockton, California
Kaiser Permanente-Vallejo Vallejo, California
Kaiser Permanente-Walnut Creek Walnut Creek, California
Kaiser San Rafael-Gallinas San Rafael, California
Kansas Institute of Medicine Cancer and Blood Center Lenexa, Kansas
Katmai Oncology Group Anchorage, Alaska	Site Public Contact - (AKPAMC.OncologyResearchSupport@providence.org)
Keck Medical Center of USC Pasadena Pasadena, California
Kettering Medical Center Kettering, Ohio
Kingman Regional Medical Center Kingman, Arizona	Site Public Contact - (research@sncrf.org)
Knox Community Hospital Mount Vernon, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
Kootenai Clinic Cancer Services - Post Falls Post Falls, Idaho	Site Public Contact - (mccinfo@mtcancer.org)
Kootenai Clinic Cancer Services - Sandpoint Sandpoint, Idaho	Site Public Contact - (mccinfo@mtcancer.org)
Kootenai Health - Coeur d'Alene Coeur d'Alene, Idaho	Site Public Contact - (mccinfo@mtcancer.org)
Lake Huron Medical Center Port Huron, Michigan
Lake Region Healthcare Corporation-Cancer Care Fergus Falls, Minnesota
Lake Regional Hospital Osage Beach, Missouri	Site Public Contact - (clinicaltrials@lakeregional.com)
Lakeview Hospital Stillwater, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Las Vegas Cancer Center-Henderson Henderson, Nevada
Las Vegas Cancer Center-Medical Center Las Vegas, Nevada
Las Vegas Prostate Cancer Center Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
Las Vegas Urology - Cathedral Rock Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
Las Vegas Urology - Green Valley Henderson, Nevada	Site Public Contact - (research@sncrf.org)
Las Vegas Urology - Pebble Henderson, Nevada	Site Public Contact - (research@sncrf.org)
Las Vegas Urology - Pecos Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
Las Vegas Urology - Smoke Ranch Las Vegas, Nevada	Site Public Contact - (research@smcrf.org)
Las Vegas Urology - Sunset Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
Laura and Isaac Perlmutter Cancer Center at NYU Langone New York, New York	Site Public Contact - (CancerTrials@nyulangone.org)
Lawrence Memorial Hospital Lawrence, Kansas
Lehigh Valley Hospital - Muhlenberg Bethlehem, Pennsylvania	Site Public Contact - (Morgan_M.Horton@lvhn.org)
Lehigh Valley Hospital-Cedar Crest Allentown, Pennsylvania	Site Public Contact - (Morgan_M.Horton@lvhn.org)
Lehigh Valley Hospital-Hazleton Hazleton, Pennsylvania	Site Public Contact - (Morgan_M.Horton@lvhn.org)
Lenox Hill Hospital New York, New York
Lewistown Hospital Lewistown, Pennsylvania
Liberty Hospital Liberty, Missouri
Licking Memorial Hospital Newark, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
Logan Health Medical Center Kalispell, Montana	Site Public Contact - (mccinfo@mtcancer.org)
Longmont United Hospital Longmont, Colorado	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Los Angeles General Medical Center Los Angeles, California
Louisiana State University Health Science Center New Orleans, Louisiana
M D Anderson Cancer Center Houston, Texas	Site Public Contact - (askmdanderson@mdanderson.org)
MU Health Care Goldschmidt Cancer Center Jefferson City, Missouri
Macomb Hematology Oncology PC Warren, Michigan
Marietta Memorial Hospital Marietta, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
Marshfield Clinic Cancer Center at Sacred Heart Eau Claire, Wisconsin
Marshfield Clinic-Chippewa Center Chippewa Falls, Wisconsin	Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org)
Marshfield Clinic-Wausau Center Wausau, Wisconsin	Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org)
Marshfield Medical Center - Minocqua Minocqua, Wisconsin	Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org)
Marshfield Medical Center - Weston Weston, Wisconsin	Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org)
Marshfield Medical Center-EC Cancer Center Eau Claire, Wisconsin	Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org)
Marshfield Medical Center-Marshfield Marshfield, Wisconsin	Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org)
Marshfield Medical Center-Rice Lake Rice Lake, Wisconsin	Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org)
Marshfield Medical Center-River Region at Stevens Point Stevens Point, Wisconsin	Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org)
Mary Greeley Medical Center Ames, Iowa
Massachusetts General Hospital Cancer Center Boston, Massachusetts
Mayo Clinic in Arizona Scottsdale, Arizona
Mayo Clinic in Florida Jacksonville, Florida
Mayo Clinic in Rochester Rochester, Minnesota
McFarland Clinic - Ames Ames, Iowa
McFarland Clinic - Boone Boone, Iowa
McFarland Clinic - Jefferson Jefferson, Iowa
McFarland Clinic - Marshalltown Marshalltown, Iowa
McFarland Clinic - Trinity Cancer Center Fort Dodge, Iowa
Medical College of Wisconsin Milwaukee, Wisconsin
Medical University of South Carolina Charleston, South Carolina
Memorial GYN Plus Ooltewah, Tennessee
Memorial Health University Medical Center Savannah, Georgia
Memorial Hermann Northeast Hospital Humble, Texas	Site Public Contact - (ctsucontact@westat.com)
Memorial Hermann Texas Medical Center Houston, Texas
Memorial Hermann The Woodlands Hospital The Woodlands, Texas	Site Public Contact - (ctsucontact@westat.com)
Memorial Hospital Chattanooga, Tennessee	Site Public Contact - (Jeffh@columbusccop.org)
Memorial Hospital Chattanooga, Tennessee
Memorial Hospital of Carbondale Carbondale, Illinois	Site Public Contact - (clinical.research@sih.net)
Memorial Hospital of South Bend South Bend, Indiana
Memorial Medical Center Modesto, California
Memorial Regional Cancer Center Day Road Mishawaka, Indiana
Memorial Sloan Kettering Basking Ridge Basking Ridge, New Jersey
Memorial Sloan Kettering Cancer Center New York, New York
Memorial Sloan Kettering Commack Commack, New York
Memorial Sloan Kettering Westchester Harrison, New York
Menorah Medical Center Overland Park, Kansas
Mercy Cancer Center Merced, California	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Mercy Cancer Center - Cape Girardeau Cape Girardeau, Missouri
Mercy Cancer Center - Carmichael Carmichael, California	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Mercy Cancer Center - Elk Grove Elk Grove, California	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Mercy Cancer Center - Rocklin Rocklin, California	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Mercy Cancer Center - Sacramento Sacramento, California	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Mercy Cancer Center-West Lakes Clive, Iowa	Site Public Contact - (cancerresearch@mercydesmoines.org)
Mercy Clinic-Rolla-Cancer and Hematology Rolla, Missouri
Mercy Health - Perrysburg Hospital Perrysburg, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
Mercy Health - Saint Anne Hospital Toledo, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
Mercy Health - Saint Vincent Hospital Toledo, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
Mercy Health Sylvania Radiation Oncology Center Toledo, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
Mercy Hospital Coon Rapids, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Mercy Hospital Fort Smith Fort Smith, Arkansas
Mercy Hospital Joplin Joplin, Missouri	Site Public Contact - (esmeralda.carrillo@mercy.net)
Mercy Hospital Oklahoma City Oklahoma City, Oklahoma
Mercy Hospital Pittsburg Pittsburg, Kansas
Mercy Hospital Saint Louis St Louis, Missouri
Mercy Hospital South St Louis, Missouri	Site Public Contact - (Danielle.Werle@mercy.net)
Mercy Hospital Springfield Springfield, Missouri
Mercy Hospital Washington Washington, Missouri
Mercy Infusion Center - Chippewa St Louis, Missouri
Mercy Medical Center Springfield, Massachusetts	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Mercy Medical Center - Des Moines Des Moines, Iowa	Site Public Contact - (cancerresearch@mercydesmoines.org)
Mercy Medical Center-West Lakes West Des Moines, Iowa	Site Public Contact - (cancerresearch@mercydesmoines.org)
Mercy Oncology and Hematology - Clayton-Clarkson Ballwin, Missouri
Mercy San Juan Medical Center Carmichael, California	Site Public Contact - (OncologyResearch@DignityHealth.org)
Methodist Medical Center of Illinois Peoria, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Miami Valley Hospital Dayton, Ohio
Miami Valley Hospital North Dayton, Ohio
Miami Valley Hospital South Centerville, Ohio
Michigan Healthcare Professionals Pontiac Pontiac, Michigan	Site Public Contact - (Emily.Crofts@trinity-health.org)
Midlands Community Hospital Papillion, Nebraska
Miller-Dwan Hospital Duluth, Minnesota	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Mills Health Center San Mateo, California
Mills-Peninsula Medical Center Burlingame, California
Minimally Invasive Surgery Hospital Lenexa, Kansas
Minnesota Oncology - Burnsville Burnsville, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Minnesota Oncology Hematology PA-Maplewood Maplewood, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Minnesota Oncology Hematology PA-Woodbury Woodbury, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Mission Hope Medical Oncology - Arroyo Grande Arroyo Grande, California	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Mission Hope Medical Oncology - Santa Maria Santa Maria, California	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Missouri Baptist Medical Center St Louis, Missouri
Missouri Baptist Sullivan Hospital Sullivan, Missouri
Moffitt Cancer Center Tampa, Florida
Montefiore Medical Center - Moses Campus The Bronx, New York
Montefiore Medical Center-Einstein Campus The Bronx, New York
Montefiore Medical Center-Weiler Hospital The Bronx, New York
Monticello Cancer Center Monticello, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Mount Carmel East Hospital Columbus, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
Mount Carmel Grove City Hospital Grove City, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
Mount Carmel Health Center West Columbus, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
Mount Carmel New Albany Surgical Hospital New Albany, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
Mount Sinai Comprehensive Cancer Center at Aventura Aventura, Florida
Mount Sinai Hospital New York, New York
Mount Sinai Medical Center Miami Beach, Florida
Mountain Blue Cancer Care Center Golden, Colorado
MultiCare Deaconess Cancer and Blood Specialty Center - Downtown Spokane, Washington
MultiCare Deaconess Cancer and Blood Specialty Center - North Spokane, Washington
MultiCare Deaconess Cancer and Blood Specialty Center - Valley Spokane Valley, Washington
Munson Medical Center Traverse City, Michigan	Site Public Contact - (crcwm-regulatory@crcwm.org)
MyMichigan Medical Center Alpena Alpena, Michigan	Site Public Contact - (CVResearch@mymichigan.org)
MyMichigan Medical Center Gladwin Gladwin, Michigan	Site Public Contact - (CVResearch@mymichigan.org)
MyMichigan Medical Center Gratiot Alma, Michigan	Site Public Contact - (CVResearch@mymichigan.org)
MyMichigan Medical Center Midland Midland, Michigan	Site Public Contact - (CVResearch@mymichigan.org)
MyMichigan Medical Center Mount Pleasant Mount Pleasant, Michigan	Site Public Contact - (CVResearch@mymichigan.org)
MyMichigan Medical Center Saginaw Saginaw, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
MyMichigan Medical Center Tawas Tawas City, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center New York, New York	Site Public Contact - (cancerclinicaltrials@cumc.columbia.edu)
NYP/Weill Cornell Medical Center New York, New York
Nebraska Cancer Specialists/Oncology Hematology West PC Grand Island, Nebraska
Nebraska Medicine-Bellevue Bellevue, Nebraska
Nebraska Medicine-Village Pointe Omaha, Nebraska
New Ulm Medical Center New Ulm, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Newark Radiation Oncology Newark, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
Newland Medical Associates-Clarkston Clarkston, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
Newland Medical Associates-Pontiac Pontiac, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
North Memorial Medical Health Center Robbinsdale, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
North Shore University Hospital Manhasset, New York
North Star Lodge Cancer Center at Yakima Valley Memorial Hospital Yakima, Washington	Site Public Contact - (Memorial-ClinicalTrials@yvmh.org)
Northwell Health/Center for Advanced Medicine Lake Success, New York
Northwest Medical Specialties PLLC Tacoma, Washington
Northwest Wisconsin Cancer Center Ashland, Wisconsin	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Northwestern Medicine Cancer Center Delnor Geneva, Illinois	Site Public Contact - (Donald.Smith3@nm.org)
Northwestern Medicine Cancer Center Warrenville Warrenville, Illinois	Site Public Contact - (Donald.Smith3@nm.org)
Northwestern University Chicago, Illinois	Site Public Contact - (cancer@northwestern.edu)
Norton Brownsboro Hospital and Medical Campus Louisville, Kentucky	Site Public Contact - (ctsucontact@westat.com)
OSF Saint Anthony's Health Center Alton, Illinois
OSF Saint Francis Medical Center Peoria, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
OSF Saint Francis Radiation Oncology at Pekin Pekin, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
OSF Saint Francis Radiation Oncology at Peoria Cancer Center Peoria, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
OSF Saint Joseph Medical Center Bloomington, Illinois
Ohio State University Comprehensive Cancer Center Columbus, Ohio
OhioHealth Mansfield Hospital Mansfield, Ohio
OhioHealth Marion General Hospital Marion, Ohio
Oklahoma Cancer Specialists and Research Institute-Tulsa Tulsa, Oklahoma
Olympic Medical Cancer Care Center Sequim, Washington
Oncology Hematology Associates of Saginaw Valley PC Saginaw, Michigan
Oncology Hematology Care Inc-Anderson Cincinnati, Ohio
Oncology Hematology Care Inc-Blue Ash Cincinnati, Ohio
Oncology Hematology Care Inc-Crestview Crestview Hills, Kentucky
Oncology Hematology Care Inc-Eden Park Cincinnati, Ohio
Oncology Hematology Care Inc-Healthplex Fairfield, Ohio
Oncology Hematology Care Inc-Kenwood Cincinnati, Ohio
Oncology Hematology Care Inc-Mercy West Cincinnati, Ohio
Oncology Las Vegas - Henderson Henderson, Nevada	Site Public Contact - (research@sncrf.org)
Oncology Las Vegas - Tenaya Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
OptumCare Cancer Care at Charleston Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
OptumCare Cancer Care at Fort Apache Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
OptumCare Cancer Care at MountainView Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
OptumCare Cancer Care at Seven Hills Henderson, Nevada	Site Public Contact - (research@sncrf.org)
Orion Cancer Care Findlay, Ohio
Overlake Medical Center Bellevue, Washington
Overlook Hospital Summit, New Jersey
PCR Oncology Arroyo Grande, California	Site Public Contact - (research@sncrf.org)
Pacific Central Coast Health Center-San Luis Obispo San Luis Obispo, California	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Pacific Gynecology Specialists Seattle, Washington
Palo Alto Medical Foundation Health Care Palo Alto, California
Palo Alto Medical Foundation-Camino Division Mountain View, California
Palo Alto Medical Foundation-Fremont Fremont, California
Palo Alto Medical Foundation-Gynecologic Oncology Mountain View, California
Palo Alto Medical Foundation-Santa Cruz Santa Cruz, California
Palo Alto Medical Foundation-Sunnyvale Sunnyvale, California
Park Nicollet Clinic - Saint Louis Park Saint Louis Park, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Parkland Health Center - Farmington Farmington, Missouri
Parkland Health Center-Bonne Terre Bonne Terre, Missouri
Parkland Memorial Hospital Dallas, Texas
PeaceHealth Saint John Medical Center Longview, Washington	Site Public Contact - (kmakin-bond@peacehealth.org)
PeaceHealth Saint Joseph Medical Center Bellingham, Washington
PeaceHealth Southwest Medical Center Vancouver, Washington	Site Public Contact - (kmakin-bond@peacehealth.org)
PeaceHealth United General Medical Center Sedro-Woolley, Washington	Site Public Contact - (rcrompton@peacehealth.org)
Peninsula Cancer Center Poulsbo, Washington
Penn State Milton S Hershey Medical Center Hershey, Pennsylvania	Site Public Contact - (CTO@hmc.psu.edu)
Penrose-Saint Francis Healthcare Colorado Springs, Colorado	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Phelps Health Delbert Day Cancer Institute Rolla, Missouri	Site Public Contact - (research@phelpshealth.org)
Piedmont Hospital Atlanta, Georgia	Site Public Contact - (ORS@piedmont.org)
Pocono Medical Center East Stroudsburg, Pennsylvania	Site Public Contact - (Morgan_M.Horton@lvhn.org)
Prisma Health Cancer Institute - Butternut Greenville, South Carolina	Site Public Contact - (Kim.Williams3@prismahealth.org)
Prisma Health Cancer Institute - Easley Easley, South Carolina	Site Public Contact - (Kim.Williams3@prismahealth.org)
Prisma Health Cancer Institute - Eastside Greenville, South Carolina	Site Public Contact - (Kim.Williams3@prismahealth.org)
Prisma Health Cancer Institute - Faris Greenville, South Carolina	Site Public Contact - (Kim.Williams3@prismahealth.org)
Prisma Health Cancer Institute - Greer Greer, South Carolina	Site Public Contact - (Kim.Williams3@prismahealth.org)
Prisma Health Cancer Institute - Seneca Seneca, South Carolina	Site Public Contact - (Kim.Williams3@prismahealth.org)
Prisma Health Cancer Institute - Spartanburg Boiling Springs, South Carolina	Site Public Contact - (Kim.Williams3@prismahealth.org)
Prisma Health Greenville Memorial Hospital Greenville, South Carolina	Site Public Contact - (Kim.Williams3@prismahealth.org)
ProHealth D N Greenwald Center Mukwonago, Wisconsin
ProHealth Oconomowoc Memorial Hospital Oconomowoc, Wisconsin
ProHealth Waukesha Memorial Hospital Waukesha, Wisconsin
Providence Alaska Medical Center Anchorage, Alaska	Site Public Contact - (AKPAMC.OncologyResearchSupport@providence.org)
Providence Cancer Institute Clackamas Clinic Clackamas, Oregon
Providence Hood River Memorial Hospital Hood River, Oregon	Site Public Contact - (canrsrchstudies@provdience.org)
Providence Newberg Medical Center Newberg, Oregon	Site Public Contact - (CanRsrchStudies@providence.org)
Providence Portland Medical Center Portland, Oregon	Site Public Contact - (CanRsrchStudies@providence.org)
Providence Regional Cancer Partnership Everett, Washington	Site Public Contact - (marilyn.birchman@providence.org)
Providence Regional Cancer System-Aberdeen Aberdeen, Washington	Site Public Contact - (deidre.dillon@providence.org)
Providence Regional Cancer System-Centralia Centralia, Washington	Site Public Contact - (deidre.dillon@providence.org)
Providence Regional Cancer System-Lacey Lacey, Washington	Site Public Contact - (deidre.dillon@providence.org)
Providence Regional Cancer System-Shelton Shelton, Washington
Providence Regional Cancer System-Yelm Yelm, Washington
Providence Saint Joseph Medical Center/Disney Family Cancer Center Burbank, California	Site Public Contact - (Najee.Boucher@providence.org)
Providence Saint Mary Regional Cancer Center Walla Walla, Washington	Site Public Contact - (Cheryl.Dodd@providence.org)
Providence Saint Vincent Medical Center Portland, Oregon	Site Public Contact - (CanRsrchStudies@providence.org)
Providence Willamette Falls Medical Center Oregon City, Oregon	Site Public Contact - (CanRsrchStudies@providence.org)
Pulmonary Medicine Center of Chattanooga-Hixson Hixson, Tennessee
Radiation Oncology Associates Reno, Nevada	Site Public Contact - (research@sncrf.org)
Radiation Oncology Centers of Nevada Central Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
Radiation Oncology Centers of Nevada Southeast Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
Radiation Oncology of Northern Illinois Ottawa, Illinois
Regions Hospital Saint Paul, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Reid Health Richmond, Indiana
Renown Regional Medical Center Reno, Nevada	Site Public Contact - (research@sncrf.org)
Research Medical Center Kansas City, Missouri
Rhode Island Hospital Providence, Rhode Island
Rice Memorial Hospital Willmar, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Ridgeview Medical Center Waconia, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Riverside Methodist Hospital Columbus, Ohio
Riverwood Healthcare Center Aitkin, Minnesota	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Rocky Mountain Cancer Centers - Pueblo Pueblo, Colorado
Rocky Mountain Cancer Centers-Lakewood Lakewood, Colorado
Rocky Mountain Cancer Centers-Longmont Longmont, Colorado
Rocky Mountain Cancer Centers-Parker Parker, Colorado
Rocky Mountain Cancer Centers-Penrose Colorado Springs, Colorado	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Rocky Mountain Cancer Centers-Thornton Thornton, Colorado
Rush MD Anderson Cancer Center Chicago, Illinois	Site Public Contact - (Cancer_Studies@rush.edu)
Rush MD Anderson Cancer Center at Rush Oak Park Oak Park, Illinois	Site Public Contact - (Cancer_Studies@rush.edu)
Rush-Copley Healthcare Center Yorkville, Illinois	Site Public Contact - (Cancer.Research@rushcopley.com)
Rush-Copley Medical Center Aurora, Illinois	Site Public Contact - (RCMC_Cancer_Research@rush.edu)
SIH Cancer Institute Carterville, Illinois	Site Public Contact - (clinical.research@sih.net)
SMC Center for Hematology Oncology Union Union, South Carolina
SSM Health Good Samaritan Mount Vernon, Illinois	Site Public Contact - (gayla.hall@ssmhealth.com)
Saint Alphonsus Cancer Care Center-Baker City Baker City, Oregon	Site Public Contact - (mccinfo@mtcancer.org)
Saint Alphonsus Cancer Care Center-Boise Boise, Idaho	Site Public Contact - (stephanie.couch@stjoeshealth.org)
Saint Alphonsus Cancer Care Center-Caldwell Caldwell, Idaho	Site Public Contact - (stephanie.couch@stjoeshealth.org)
Saint Alphonsus Cancer Care Center-Nampa Nampa, Idaho
Saint Alphonsus Cancer Care Center-Ontario Ontario, Oregon	Site Public Contact - (mccinfo@mtcancer.org)
Saint Ann's Hospital Westerville, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
Saint Anthony Hospital Lakewood, Colorado	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Saint Anthony North Hospital Westminster, Colorado	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Saint Charles Health System Bend, Oregon	Site Public Contact - (nosall@stcharleshealthcare.org)
Saint Charles Health System-Redmond Redmond, Oregon
Saint Clare Hospital Lakewood, Washington
Saint Elizabeth Hospital Enumclaw, Washington
Saint Elizabeth Regional Medical Center Lincoln, Nebraska
Saint Francis Cancer Center Greenville, South Carolina	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Saint Francis Hospital Federal Way, Washington
Saint Francis Medical Center Cape Girardeau, Missouri	Site Public Contact - (sfmc@sfmc.net)
Saint Francis Regional Medical Center Shakopee, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Saint James Community Hospital and Cancer Treatment Center Butte, Montana
Saint John's Hospital - Healtheast Maplewood, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Saint Joseph Hospital Lexington, Kentucky	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
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Saint Joseph London London, Kentucky	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
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Saint Joseph's Hospital and Medical Center Phoenix, Arizona
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Saint Luke's Cancer Institute - Boise Boise, Idaho	Site Public Contact - (eslinget@slhs.org)
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Saint Mary's Oncology/Hematology Associates of Marlette Marlette, Michigan
Saint Mary's Oncology/Hematology Associates of West Branch West Branch, Michigan
Saint Mary's Regional Medical Center Reno, Nevada	Site Public Contact - (research@sncrf.org)
Saint Michael Cancer Center Silverdale, Washington	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Saint Patrick Hospital - Community Hospital Missoula, Montana	Site Public Contact - (amy.hanneman@providence.org)
Saint Peter's Community Hospital Helena, Montana
Saint Rita's Medical Center Lima, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
Saint Vincent Healthcare Billings, Montana
Sainte Genevieve County Memorial Hospital Sainte Genevieve, Missouri
Saints Mary and Elizabeth Hospital Louisville, Kentucky
Skagit Regional Health Cancer Care Center Mount Vernon, Washington	Site Public Contact - (rcccclinicalresearch@skagitvalleyhospital.org)
Smilow Cancer Hospital Care Center at Saint Francis Hartford, Connecticut	Site Public Contact - (canceranswers@yale.edu)
Smilow Cancer Hospital Care Center-Trumbull Trumbull, Connecticut	Site Public Contact - (canceranswers@yale.edu)
South Jordan Health Center South Jordan, Utah
Southern Illinois University School of Medicine Springfield, Illinois
Southern Ohio Medical Center Portsmouth, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
Southwest Illinois Health Services LLP Swansea, Illinois
Spartanburg Medical Center Spartanburg, South Carolina
Springfield Clinic Springfield, Illinois
Springfield Memorial Hospital Springfield, Illinois	Site Public Contact - (pallante.beth@mhsil.com)
Springfield Regional Cancer Center Springfield, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
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Strecker Cancer Center-Belpre Belpre, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
Summerlin Hospital Medical Center Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
Sunrise Hospital and Medical Center Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
Sutter Auburn Faith Hospital Auburn, California
Sutter Cancer Centers Radiation Oncology Services-Auburn Auburn, California
Sutter Cancer Centers Radiation Oncology Services-Cameron Park Cameron Park, California
Sutter Cancer Centers Radiation Oncology Services-Roseville Roseville, California
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Sutter Medical Center Sacramento Sacramento, California
Sutter Pacific Medical Foundation Santa Rosa, California
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Sutter Solano Medical Center/Cancer Center Vallejo, California
Swedish Cancer Institute-Edmonds Edmonds, Washington	Site Public Contact - (PCRC-NCORP@Swedish.org)
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Swedish Medical Center-Cherry Hill Seattle, Washington	Site Public Contact - (PCRC-NCORP@Swedish.org)
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Tamarack Health Hayward Medical Center Hayward, Wisconsin
Tampa General Hospital Tampa, Florida	Site Public Contact - (syapchanyk@tgh.org)
The Carle Foundation Hospital Urbana, Illinois	Site Public Contact - (Research@carle.com)
The Mark H Zangmeister Center Columbus, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
Torrance Memorial Medical Center Torrance, California
Torrance Memorial Physician Network - Cancer Care Torrance, California	Site Public Contact - (courtney.steeneken@tmphysicians.com)
TriHealth Cancer Institute-Anderson Cincinnati, Ohio	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
TriHealth Cancer Institute-Westside Cincinnati, Ohio	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Trinity Health Grand Rapids Hospital Grand Rapids, Michigan	Site Public Contact - (crcwm-regulatory@crcwm.org)
Trinity Health IHA Medical Group Hematology Oncology - Brighton Brighton, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
Trinity Health IHA Medical Group Hematology Oncology - Canton Canton, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital Chelsea, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus Ypsilanti, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
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Trinity Health Muskegon Hospital Muskegon, Michigan	Site Public Contact - (crcwm-regulatory@crcwm.org)
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Tufts Medical Center Boston, Massachusetts	Site Public Contact - (ContactUsCancerCenter@TuftsMedicalCenter.org)
UC Irvine Health/Chao Family Comprehensive Cancer Center Orange, California	Site Public Contact - (ucstudy@uci.edu)
UC San Diego Medical Center - Hillcrest San Diego, California
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UCHealth University of Colorado Hospital Aurora, Colorado
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West Virginia University Healthcare Morgantown, West Virginia
Western Illinois Cancer Treatment Center Galesburg, Illinois
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Yale University New Haven, Connecticut	Site Public Contact - (canceranswers@yale.edu)
Zangmeister Center Grove City Grove City, Ohio	Site Public Contact - (Jeffh@columbusccop.org)

Research Participation With Transgender and Gender-Diverse Youth

Contact(s):

An Pham, MD - an.pham@vcuhealth.org

Principal Investigator:

System ID: NCT05927350

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Interventions: OTHER: Survey

Conditions: Transgender Persons

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Virginia Commonwealth University Richmond, Virginia	An Pham - (an.pham@vcuhealth.org)

Using Dichoptic Therapy to Treat Intermittent Exotropia

Contact(s):

Evan Silverstein - evan.silverstein@vcuhealth.org

Principal Investigator:

System ID: NCT06529016

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Interventions: DEVICE: Luminopia, a virtual reality headset, OTHER: Paper pre- survey, OTHER: Paper Survey

Conditions: Exotropia Intermittent

Keywords: Dichoptic therapy

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Virginia Commonwealth University Richmond, Virginia	Evan Silverstein, MD - (evan.silverstein@vcuhealth.org) Emilia Varrone - (emilia.varrone@vcuhealth.org)

National Liver Cancer Screening Trial (TRACER)

Contact(s):

Amit Singal, MD, MS - Amit.Singal@UTSouthwestern.edu

Principal Investigator:

System ID: NCT06084234

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Inclusion Criteria:

Patient must meet all of the following inclusion criteria:
• Adult patients ages 18-85 with cirrhosis from any etiology or with chronic hepatitis B with a PAGE-B score greater than 9 within 12 months of enrollment
• Patient is eligible for HCC surveillance according to treating physician or by the site investigator
• Able to provide informed consent
• Life expectancy \>6 months (after consent) as determined by the treating provider or site investigator

Exclusion Criteria:

Patient will be excluded for any of the following exclusion criteria:
• Child Pugh C cirrhosis
• History or clinical symptoms of hepatocellular carcinoma or cholangiocarcinoma
• History of solid nodule on baseline ultrasound (i.e., lesion 1cm or greater) within 9 months prior to consent without subsequent diagnostic CT/MRI demonstrating benign nature)
• AFP \>20 ng/mL within 6 months prior to consent, in the absence of a contrast-enhanced CT or MRI within 6 months of AFP (before or after) level demonstrating lack of suspicious liver lesions
• Newly diagnosed LR-3 greater than or equal to 1 cm within 6 months prior to consent
• History of LR-4, LR-5, or LR-M on multi-phase CT or contrast-enhanced MRI within 6 months prior to consent
• Presence of another active cancer besides non-melanomatous skin cancer or indolent cancer under active surveillance (e.g., prostate cancer or renal cell carcinoma) within the 2 years prior to consent
• Patient's provider is planning to use MRI- or CT- based surveillance moving forward
• History of a transjugular intrahepatic portosystemic shunt (TIPS)
• History of Fontan associated liver disease or cardiac cirrhosis
• History of solid organ transplantation
• Actively listed for liver transplantation
• Diagnosis of alcohol-associated hepatitis within 3 months prior to consent
• Documented current or continued signs and symptoms of acute Wilson disease (acute liver failure, acute neurological deficits, hemolysis)
• In patients with primary sclerosing cholangitis (PSC): Current active cholangitis within 90 days prior to consent
• Known or documented habitual non-adherence to previous research studies or medical procedures or unwillingness to adhere to protocol (e.g., unwilling to obtain consent or samples)
• In patients living with HIV: CD4+ T cell count less than 100 cells/mm3 within 60 days prior to consent
• Known pregnancy at consent
• Active warfarin use

Interventions: DIAGNOSTIC_TEST: GALAD, DIAGNOSTIC_TEST: Liver Ultrasound with or without AFP

Conditions: Carcinoma, Hepatocellular, Liver Cancer, Liver Cirrhosis, Hepatitis B

Keywords: Hepatocellular carcinoma surveillance, GALAD, Alpha Fetoprotein

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Location	Contacts
Baylor College of Medicine Houston, Texas	Emad Sorial - (Emad.Sorial@bcm.edu) - (Sara.Fares@bcm.edu)
Hennepin Healthcare Minneapolis, Minnesota	Jose Debes, MD - (debes003@umn.edu) Daniel Akah - (Dakah@bermancenter.org)
Henry Ford Health System Detroit, Michigan	Jessica Peruski - (jperusk1@hfhs.org)
Indiana University Indianapolis, Indiana	Sherri Cummins - (shcummin@iu.edu)
Kaiser Permanente Fresno, California	Sreepriya Balasubramanian, MD, MPH - (Sreepriya.Balasubramanian@kp.org) Quyen Chau - (Quyen.X.Chau@kp.org)
Massachusetts General Hospital Boston, Massachusetts	Megan Michta - (MMICHTA@mgh.harvard.edu)
Northwestern University Chicago, Illinois	Laura Kulik, MD - (laura.kulik@nm.org) Kimberly Sipich - (k-sipich@northwestern.edu)
Stanford University Stanford, California	Paul Kwo, MD - (pkwo@stanford.edu) Jennifer Smart - (Jsmart2@stanford.edu)
The Feinstein Institutes, Northwell Health, Inc. Manhasset, New York	Dibnain Nanda - (dnanda1@northwell.edu)
UT Southwestern Medical Center and Parkland Hospital Dallas, Texas	Sneha Deodhar, MS - (TRACER@UTSouthwestern.edu)
University of California, San Francisco San Francisco, California	Rae Davis - (rayshawnda.davis@ucsf.edu)
University of Michigan Ann Arbor, Michigan	Shay Robison - (roshay@med.umich.edu)
University of Minnesota Minneapolis, Minnesota	Elizabeth Aby, MD - (abyxx002@umn.edu) Erin Wesley - (wesle091@umn.edu)
University of North Carolina Chapel Hill, North Carolina	Andrew Moon, MD - (Andrew.Moon@unchealth.unc.edu) Bhagyashree Behera - (BB_Behera@med.unc.edu)
University of Pennsylvania Philadelphia, Pennsylvania	Grace Kim - (gracekim.lee@pennmedicine.upenn.edu)
University of Southern California Los Angeles, California
Virginia Commonwealth University Richmond, Virginia	Hannah Lee, MD - (Hannah.Lee@vcuhealth.org) Hannah Cook - (Hannah.Cook1@vcuhealth.org)

TAK-243 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndromes With Increased Blasts

Contact(s):

ctrrecruit@vcu.edu

Principal Investigator:

System ID: NCT03816319

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Inclusion Criteria:

* Diagnosis of AML or MDS with increased blasts (MDS-IB) assessed by local laboratory review according to the 2022 World Health Organization (WHO) criteria for myeloid neoplasms. Both patients with MDS-IB1 (5-9% bone marrow blasts) and MDS-IB2 (10-19% bone marrow blasts) are eligible. * Patients must have relapsed or refractory disease after receiving at least one prior line of therapy * AML-specific inclusion criteria: Patients with relapsed or refractory AML with \>= 5% bone marrow blasts after receiving at least two courses of intensive induction chemotherapy (including, but not limited to, 7+3 regimen, fludarabine, cytarabine, idarubicin and filgrastim \[FLAG-Ida\] and mitoxantrone, etoposide, and cytarabine \[MEC\]) or 2 cycles of venetoclax-based lower intensity regimen (azacitidine plus venetoclax or low-dose cytarabine plus venetoclax), and without any other approved therapies available that would be more appropriate in the investigator's judgment. Patients who have received only one course of intensive induction chemotherapy but are not eligible for a second course because of decreased performance status or clear disease progression may be eligible for participation after discussion with the study principal investigator (PI). Patients with concomitant extramedullary disease relapse are eligible to participate, but not patients with isolated extramedullary relapse without bone marrow disease. * MDS-specific inclusion criteria: Patients with relapsed or refractory MDS-IB with \>= 5% bone marrow blasts after at least 4 cycles of hypomethylating agent (HMA)-based therapy or at least two courses of intensive induction chemotherapy and meet criteria for stable disease (SD), progressive disease (PD) or disease relapse according to the International Working Group 2023 response criteria for higher-risk MDS. Patients must not have access to any other approved therapies that would be more appropriate in the investigator's judgment. Patients who have received less than 4 cycles of HMA-based therapy may be eligible to participate after discussion with the study PI if there is clear evidence of progression or intolerance to HMA-based therapy that precludes its continuation. * Patients must have recovered from the effects of any prior systemic therapy, radiotherapy or surgery: * Patients should not have received other investigational therapy within 2 weeks. * Patients should not have received standard chemotherapy within 1 week of administration of study drug; hydroxyurea administration (for leukocyte count control) is permitted. * Age \>=18 years. Because no dosing or adverse event data are currently available on the use of TAK-243 in patients \<18 years of age, children are excluded from this study. * Eastern Cooperative Oncology Group (ECOG) performance status =\< 2 (Karnofsky \>= 50%). * Serum bilirubin =\< 1.5 × institutional upper limit of normal (ULN). * Patients with a known history of Gilbert's syndrome may enroll. * Aspartate aminotransferase (AST) (serum glutamic oxaloacetic transaminase \[SGOT\])/alanine aminotransferase (ALT) (serum glutamate pyruvate transaminase \[SGPT\]) =\< 3 × institutional ULN. * Serum creatinine \< 176 mcmol/L (2 mg/dL) OR * Creatinine clearance \> 60 mL/min based on the Cockcroft-Gault equation. * Documented normal cardiac function (\>= 50%) by echocardiogram or multi-gated acquisition (MUGA) scan. * HIV-infected patients on effective anti-retroviral therapy with undetectable viral load withing 6 months are eligible for this trial. * For patients with evidence of chronic hepatitis B virus (HBV) infection, HBV viral load must be undetectable on suppressive therapy if indicated. * Patients with a history of hepatitis C virus (HCV) infection must have been treated and cured. For patients with HCV infection who are currently on treatment, they are eligible if they have an undetectable HCV viral load. * The effects of TAK-243 on the developing human fetus are unknown and ubiquitin-activating enzyme inhibitors are known to be teratogenic. For this reason, female patients must be: * Postmenopausal (age-related amenorrhea \>= 12 consecutive months or follicle-stimulating hormone \> 40 mIU/mL), for at least 1 year before the screening visit, OR * Surgically sterile (i.e., who had undergone hysterectomy or bilateral oophorectomy), OR If they are of childbearing potential: * Agree to practice 1 highly effective method and 1 additional effective (barrier) method of contraception, at the same time, from the time of signing the informed consent through 4 months after the last dose of study drug (female and male condoms should not be used together), OR * Agree to practice true abstinence, when this is in line with the preferred and usual lifestyle of the patient. (Periodic abstinence \[e.g., calendar, ovulation, symptothermal, postovulation methods\] withdrawal, spermicides only, and lactational amenorrhea are not acceptable methods of contraception.) Should a woman become pregnant or suspect she is pregnant while she or her partner is participating in this study, she should inform her treating physician immediately. * Male patients, even if surgically sterilized (i.e., status post-vasectomy), who: * Agree to practice effective barrier contraception during the entire study treatment period and through 4 months after the last dose of study drug (female and male condoms should not be used together), OR * Agree to practice true abstinence, when this is in line with the preferred and usual lifestyle of the subject. (Periodic abstinence \[e.g., calendar, ovulation, symptothermal, postovulation methods for the female partner\] withdrawal, spermicides only, and lactational amenorrhea are not acceptable methods of contraception.) * Ability to understand and the willingness to sign a written informed consent document. Legally authorized representatives may sign and give informed consent on behalf of study participants. * Patients should have a minimum life expectancy of 1 month.

Exclusion Criteria:

* Patients with acute promyelocytic leukemia (APL) or AML with t(15;17)(q22;q12) - PML::RARA). * Patients who have not recovered from adverse events due to prior anti-cancer therapy (i.e., have residual toxicities \> grade 1), except anemia, neutropenia or thrombocytopenia of any grade and grade 2 peripheral neuropathy. * Presence of any other malignancy requiring active therapy. * Patients who are receiving any other investigational agents. * History of allergic reactions attributed to compounds of similar chemical or biologic composition to TAK-243. * Concomitant treatment with organic anion transport protein (OATP) and BCRP inhibitors or strong inducers/inhibitors of cytochrome P450 (CYP)3A4/5. Treatment with these agents must be discontinued at least 14 days prior to TAK-243 dosing. Because the lists of these agents are constantly changing, it is important to regularly consult a frequently updated medical reference. As part of the enrollment/informed consent procedures, the patient will be counseled on the risk of interactions with other agents, and what to do if new medications need to be prescribed or if the patient is considering a new over-the-counter medicine or herbal product. * Presence of an active uncontrolled infection or severe infectious disease, such as severe pneumonia, meningitis, or septicemia. * Presence of active graft-versus-host disease (GVHD) or continued treatment with systemic immunosuppressive agents following allogeneic hematopoietic stem cell transplantation (HSCT). * Presence of any co-morbid condition that, in the opinion of the investigator, might compromise the patient's safety, might interfere with participation in the trial or might interfere with the interpretation of trial results. * Pregnant and lactating/breast-feeding women are excluded from this study because TAK-243 is a UAE-inhibiting agent with the potential for teratogenic or abortifacient effects and there is an unknown but potential risk for adverse events in nursing infants secondary to treatment of the mother with TAK-243. Females of child-bearing potential must have a negative serum pregnancy test within 7 days before enrollment and should not be lactating/breast-feeding. Breastfeeding should be discontinued if the mother is treated with TAK-243. * Major surgery within 14 days before the first dose of any study drug or a scheduled surgery during study period. * Patients with uncontrolled coagulopathy or bleeding disorder. * Patients with known hepatic cirrhosis. * Patients with known active cardiopulmonary disease defined as: * Unstable angina withing 3 months prior to first dose of TAK-243; * Myocardial infarction (MI) within 6 months prior to first dose of TAK-243 (patients who had MI and/or coronary revascularization more than 6 months before screening and who are without cardiac symptoms may enroll); * Congestive heart failure (New York Heart Association \[NYHA\] Class III or IV; * Cardiomyopathy with left ventricular ejection fraction (LVEF) \< 50%; * Symptomatic pulmonary hypertension. * Presence of active central nervous system (CNS) involvement (patients with prior CNS leukemia who have negative CNS cytology and who receive periodic prophylactic intrathecal chemotherapy are eligible). * Patients with clinically significant arrhythmia: * History of ventricular fibrillation or torsade de pointes at any time, * Episode of grade \>= 3 atrial fibrillation or flutter in the last 3 months, defined as symptomatic episode, requiring urgent intervention (cardioversion, pacemaker or ablation) or with life-threatening consequences. * Uncontrolled high blood pressure (i.e., systolic blood pressure \>180 mm Hg, diastolic blood pressure \> 95 mm Hg). * Prolonged rate corrected QT (QTc) interval \>= 480 msec, calculated using the Fridericia method. * Patients with known severe or very severe chronic obstructive pulmonary disease (defined as forced expiratory volume in one second (FEV1) less than 30% or less than 50% of predicted), interstitial lung disease, or pulmonary fibrosis. * Female patients who intend to donate eggs (ova) during the course of this study or 4 months after receiving their last dose of study drug(s). * Male patients who intend to donate sperm during the course of this study or 4 months after receiving their last dose of study drug(s). * Patients with history of neutrophilic dermatosis (e.g. Sweet syndrome, pyoderma gangrenosum), relapsing polychondritis, polyarteritis nodosa and/or giant cell arteritis. * Patients with VEXAS syndrome (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic syndrome) or any other autoinflammatory disease.

Interventions: PROCEDURE: Biospecimen Collection, PROCEDURE: Bone Marrow Aspiration, PROCEDURE: Bone Marrow Biopsy, PROCEDURE: Echocardiography Test, PROCEDURE: Multigated Acquisition Scan, DRUG: UAE Inhibitor TAK-243

Conditions: Myelodysplastic Syndrome With Excess Blasts, Recurrent Acute Myeloid Leukemia, Recurrent Myelodysplastic Syndrome, Recurrent Myelodysplastic Syndrome/Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia, Refractory Myelodysplastic Syndrome, Refractory Myelodysplastic Syndrome/Acute Myeloid Leukemia

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Location	Contacts
Moffitt Cancer Center Tampa, Florida	Site Public Contact - (ClinicalTrials@moffitt.org)
Northwestern University Chicago, Illinois	Site Public Contact - (cancer@northwestern.edu)
University Health Network-Princess Margaret Hospital Toronto, Ontario	Site Public Contact - (clinical.trials@uhn.on.ca)
VCU Massey Comprehensive Cancer Center Richmond, Virginia	Site Public Contact - (CTOclinops@vcu.edu)

CRISPR-Edited Allogeneic Anti-BCMA CAR-T Cell Therapy in Patients With Relapsed/Refractory Multiple Myeloma (CaMMouflage)

Contact(s):

Caribou Biosciences - clinicaltrials@cariboubio.com

Principal Investigator:

System ID: NCT05722418

Show full eligibility criteria

Interventions: BIOLOGICAL: CB-011

Conditions: Relapsed/Refractory Multiple Myeloma

Keywords: CaMMouflage, Allogeneic, Multiple Myeloma, Relapse Refractory Multiple Myeloma, CAR-T Cells, BCMA, Cell Therapy, Cellular Immuno-therapy, CB11A, CB-011, CB-011A, CAR-T, Anti BCMA, ALLO CAR T

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Location	Contacts
CU Anschutz Medical Campus, Anshutz Cancer Pavillion Aurora, Colorado	Rona Wang - (deng.wang@cuanschutz.edu) Natalie Pfenning - (natalie.pfenning@cuanschutz.edu)
Cleveland Clinic Cleveland, Ohio	- (Canceranswer@ccf.org)
Duke University Health System (DUHS) Durham, North Carolina	Matthew Fisher - (Matthew.Fister@Duke.edu)
Froedtert and The Medical College of Wisconsin Milwaukee, Wisconsin	Danielle King - (daking@mcw.edu)
Hackensack Meridian John Theurer Cancer Center Hackensack, New Jersey	Oncology Clinical Research Referral Office - (oncologyresearchreferral@hmhn.org)
Huntsman Cancer Institute, University of Utah Salt Lake City, Utah	Collind Boyington - (collind.boyington@HCI.UTAH.EDU)
Icahn School of Medicine at Mount Sinai New York, New York	Adriana Rossi, MD - (adriana.rossi@mssm.edu)
Levine Cancer Institute Charlotte, North Carolina	Kelly Bumgarner - (Kelly.Bumgarner@atriumhealth.org)
Memorial Sloan Kettering Cancer Center New York, New York	Sham Mailankody, MBBS - (cart@mskcc.org)
Oncology Hematology Care, Inc Cincinnati, Ohio	Doug Hart - (douglas.hart@usoncology.com)
Sylvester Comprehensive Cancer Center, University of Miami Hospital and Clinics Miami, Florida	Jay Spiegel, MD - (Spiegelj@med.miami.edu)
Tennessee Oncology Nashville, Tennessee	Jesus Berdeja, MD - (jberdeja@tnonc.com) Taylor Peach - (tpeach@tnonc.com)
University of Alabama at Birmingham Birmingham, Alabama	Luciano Costa, MD - (ljcosta@uabmc.edu)
University of Kentucky/ Markey Cancer Center Lexington, Kentucky	Ashley Walton-Robbins - (Ashley.robbins@uky.edu)
University of Texas Southwestern Medical Center Dallas, Texas	Marcella Aguilar - (Marcella.Aguilar@utsouthwestern.edu)
Virginia Commonwealth University Richmond, Virginia	Johanna Biamonte - (jbiamonte@vcu.edu)

Safety and Effectiveness of Valbenazine as Adjunct Therapy to Botulinum Toxin Injections in Cervical Dystonia

Contact(s):

Ananna Zaman - Ananna.Zaman@vcuhealth.org

Principal Investigator:

System ID: NCT06771323

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Interventions: DRUG: Valbenazine, DRUG: Placebo

Conditions: Cervical Dystonia

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Location	Contacts
Virginia Commonwealth University Richmond, Virginia	Caileigh Dintino - (caileigh.dintino@vcuhealth.org) Brian Berman - (bermanbd2@vcu.edu)

Reduced CT + Anti-PD-1 as First Line Tx in Vulnerable Older Adults w/Adv <50% PD-L1 Non-Small Cell Lung Cancer (NSCLC)

Contact(s):

Massey IIT Research Operations - masseyepd@vcu.edu

Principal Investigator:

System ID: NCT06731413

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Inclusion Criteria:

* Histologically or cytologically confirmed diagnosis of non-small cell lung cancer (NSCLC) (either squamous or non- squamous) * Stage IV disease OR have recurrent disease and not be candidates for curative treatment such as combined chemo-radiation * No previous line of treatment in the recurrent or metastatic setting. Neoadjuvant or adjuvant treatment more than 6 months before enrollment is acceptable. * Age 70 or meeting frailty definition or above at the date of signing informed consent * Absence of driver mutations that have first line Food and Drug Administration (FDA) approved targeted therapy * PD-L1 tumor proportion score (TPS) of less than 50% * Eastern Cooperative Oncology Group (ECOG) PS of 0-3 * Have measurable disease based on RECIST 1.1 as determined by the local site investigator/radiology assessment * Absolute neutrophil count (ANC) ≥ 1,000/μL * Platelets ≥ 75,000/μL * Hemoglobin (Hgb) ≥ 8.0 g/dL (transfusion permitted) * Total bilirubin ≤ 2 x institutional upper limit of normal (ULN) * Aspartate amino transferase (AST)serum glutamic-oxaloacetic transaminase (SGOT) /alanine aminotransferase (ALT)serum glutamic-pyruvic transaminase (SGPT) ≤ 5.0 × institutional ULN * Ability to understand and the willingness to sign a written informed consent document

Exclusion Criteria:

* Participants with life expectancy of less than 3 months at the time of enrollment * Has active autoimmune disease that has required systemic treatment in past 2 years (ie, with use of disease modifying agents, or immunosuppressive drugs) * Diagnosis of interstitial lung disease * Creatinine clearance of \<30 mL/min * Symptomatic, untreated central nervous system (CNS) disease or leptomeningeal disease. Patients with asymptomatic or treated CNS disease are eligible * Required ongoing use of immunosuppressive medication, including steroids, with the following allowable exceptions: * Doses less than or equal to the equivalent of prednisone 10 mg daily * Short courses of steroids that are discontinued prior to enrollment * Inhaled, intranasal and/or topical steroids * Dexamethasone taper for treating vasogenic edema associated with CNS disease

Interventions: DRUG: Reduced Dose of Chemotherapy and Immunotherapy

Conditions: Non-small Cell Lung Cancer, NSCLC, Advanced Non-small Cell Lung Cancer, Metastatic Non Small Cell Lung Cancer

Keywords: Non-Small Cell Lung Cancer, NSCLC

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Location	Contacts
Virginia Commonwealth University Richmond, Virginia	Massey Lung Team - (masseylung@vcu.edu)

HPV DNA-Guided Radiotherapy De-intensification of Head and Neck Squamous Cell Carcinoma (HN001)

Contact(s):

Song W - UVARADONCClinicalTrials@uvahealth.org

Principal Investigator:

System ID: NCT05962242

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Inclusion Criteria:

• Provision of signed and dated informed consent form
• Stated willingness to comply with all study procedures and availability for the duration of the study
• Male or female, ≥ 18 years of age
• Pathologically proven diagnosis of squamous cell carcinoma of the oropharynx of any AJCC 8th edition stage.
• Eligible for and planning to receive definitive treatment or adjuvant treatment with radiotherapy.
• Participants who are receiving concurrent systemic anticancer therapy (e.g. chemotherapy or immunotherapy) for oropharyngeal cancer are eligible.
• For participants with T1-2 and N0 disease, chemotherapy is not required for eligibility. Participants may or may not receive chemotherapy per physician discretion.
• For participants with T3-4 and/or N+ disease, chemotherapy is required for eligibility.
• Participants may receive investigational agents with prior approval from the Principal Investigator.
• ECOG Performance Status of 0-2.
• p16 positive HPV as determined by NavDx and immunohistochemistry
• For females of reproductive potential: agreement to use adequate contraception during radiation treatment and for 6 months (or more if applicable based on other medications) after the end of radiation treatment.

Exclusion Criteria:

• Evidence of distant metastatic disease
• Prior history of radiotherapy to the head and/or neck
• Had surgery for oropharyngeal cancer within 8 months of enrollment unless it was an incomplete oncologic surgery. Participant is eligible if the gross tumor was not completely removed.
• Diagnosis of T3-4 and/or N+ disease with no plans to receive concurrent chemotherapy.
• Diagnosis of a current or prior invasive malignancy (except non-melanoma skin cancer) unless the participant has been disease free for at least 3 years.
• Participant is a prisoner
• Known contraindications to head and neck radiation therapy such as ataxia telangiectasia or scleroderma.
• Pregnancy or lactation
• Active or severe co-morbidities as defined by the following:
• Unstable angina and/or congestive heart failure requiring hospitalization up to 180 days before registration
• Transmural myocardial infarction up to 180 days before registration
• Acute bacterial or fungal infection requiring intravenous antibiotics at the time of registration
• Chronic obstructive pulmonary disease exacerbation or other respiratory illness requiring hospitalization or precluding study therapy at the time of registration
• Hepatic insufficiency as determined by the treating clinician resulting in clinical jaundice and/or coagulation effects or severe liver dysfunction.
• Acquired immune deficiency syndrome (AIDS) based upon current CDC definition. The need to exclude patients with AIDS from this protocol is necessary because the treatments involved in this protocol may be slightly immunosuppressive. Protocol-specific requirements may also exclude immuno-compromised patients.
• Tobacco smoking history of 10 pack years or greater, or ≥ 20 pack years if smoking cessation occurred at least 1 year prior to enrollment
• Current use of antineoplastic drugs for other malignancies.

Interventions: RADIATION: Radiation Therapy

Conditions: Squamous Cell Carcinoma of the Oropharynx

Keywords: Radiation Therapy, Radiotherapy, Head Cancer, Neck Cancer, Low Dose Radiation, HPV

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Study Locations

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Location	Contacts
Bon Secours Cork,
Eastern Virginia Medical School Norfolk, Virginia
Miami Cancer Institute Miami, Florida	Noah Kalman, M.D. - (noahk@baptisthealth.net)
University of Virginia Charlottesville, Virginia	Song W - (UVARADONCClinicalTrials@uvahealth.org)
Virginia Commonwealth University Richmond, Virginia

mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma

Contact(s):

Aishwarya Vijendran - aishwaryav@bsd.uchicago.edu

Principal Investigator:

System ID: NCT05677490

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Inclusion Criteria:

* Histologic documentation: HER2 negative adenocarcinoma as defined by American Society of Clinical Oncology (ASCO) College of American Pathologists (CAP) guidelines (Bartley et al., Journal of Clinical Oncology \[JCO\] 2017) with known PD-L1 CPS (Any CPS is allowed, but should be known prior to registration) * Stage: unresectable or metastatic * Tumor site: esophagus, gastroesophageal junction, or stomach * Measurable disease or non-measurable but evaluable disease as defined by Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 * No prior treatment for unresectable or metastatic disease * Prior neoadjuvant or adjuvant cytotoxic chemotherapy or adjuvant immunotherapy is allowed as long as it was completed at least 1 year prior to registration * Age \>= 18 years * Eastern Cooperative Oncology Group (ECOG) Performance Status 0 or 1 * Absolute neutrophil count (ANC) \>= 1,500/mm\^3 * Platelet count \>= 100,000/mm\^3 * Creatinine =\< 1.5 x upper limit of normal (ULN) OR calculated (calc.) creatinine clearance \>= 30 mL/min * Total bilirubin =\< 1.5 x ULN * Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) =\< 3 x ULN (in patients with liver metastasis: =\< 5 x ULN if clearly attributable to liver metastases) * Patients with a prior or concurrent malignancy whose natural history or treatment does not have the potential to interfere with the safety or efficacy assessment of the investigational regimen are eligible for this trial * Patients positive for human immunodeficiency virus (HIV) are eligible only if they meet all of the following: * On effective anti-retroviral therapy * Undetectable HIV viral load by standard clinical assay =\< 6 months of registration * Patients with known history or current symptoms of cardiac disease, or history of treatment with cardiotoxic agents, should have a clinical risk assessment of cardiac function using the New York Heart Association Functional Classification. To be eligible for this trial, patients should be class 2B or better * Patients who will receive nivolumab in addition to chemotherapy must not have any contraindications to immune checkpoint inhibitors * Patients must not have active autoimmune disease that has required systemic treatment within 6 months prior to registration. Patients are permitted to receive immunotherapy if they have vitiligo, type I diabetes, residual hypothyroidism due to autoimmune condition only requiring hormone replacement, psoriasis not requiring systemic treatment, or conditions not expected to recur in the absence of an external trigger (precipitating event) * Patients must not have a condition requiring systemic treatment with either corticosteroids (\>10mg/day prednisone equivalents) or other immunosuppressive medications within 14 days prior to registration. Inhaled or topical steroids and adrenal replacement doses (=\< 10mg/day prednisone equivalent) are permitted * Patients must not have a history of noninfectious pneumonitis requiring steroids * Patients with prior immune mediated adverse events related to immunotherapy that resulted in permanent treatment discontinuation with these agents are ineligible * This study includes the use of the mandatory patient completed measure, PRO-CTCAE. For this study the PRO-CTCAE is available in English, Spanish, Korean, Chinese (Simplified), and Russian, hence patients must be able to speak, understand and read in these languages. Ad-hoc translation of patient-reported measures is not permitted

Exclusion Criteria:

* Not pregnant and not nursing, because this study involves an agent that has known genotoxic, mutagenic and teratogenic effects \* Therefore, for women of childbearing potential only, a negative serum or urine pregnancy test done =\< 7 days prior to registration is required * No known Gilbert's syndrome or known homozygosity for UGAT1A1\*28 polymorphism * No baseline grade \>= 2 peripheral neuropathy, neurosensory toxicity, or neuromotor toxicity per CTCAE version (v) 5.0 regardless of causality * No medical condition such as uncontrolled infection or uncontrolled diabetes mellitus which, in the opinion of the treating physician, would make this protocol unreasonably hazardous for the patient * No untreated, symptomatic brain metastasis. Patients with treated brain metastases are eligible if the following criteria are met: 1) follow-up brain imaging done at least in 4 weeks after central nervous system (CNS)-directed therapy shows no evidence of progression and 2) the patient no longer requires steroids, or is on a stable steroid dose for more than four weeks * No allogeneic tissue/organ transplant

Interventions: DRUG: Fluorouracil, DRUG: Leucovorin Calcium, DRUG: Oxaliplatin, DRUG: Irinotecan, BIOLOGICAL: Nivolumab, PROCEDURE: Magnetic Resonance Imaging, PROCEDURE: Computed Tomography, PROCEDURE: Biospecimen Collection, OTHER: Questionnaire Administration

Conditions: Advanced Esophageal Adenocarcinoma, Advanced Gastric Adenocarcinoma, Advanced Gastroesophageal Junction Adenocarcinoma, Clinical Stage III Esophageal Adenocarcinoma AJCC v8, Clinical Stage III Gastric Cancer AJCC v8, Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8, Clinical Stage IV Esophageal Adenocarcinoma AJCC v8, Clinical Stage IV Gastric Cancer AJCC v8, Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8, Metastatic Esophageal Adenocarcinoma, Metastatic Gastric Adenocarcinoma, Metastatic Gastroesophageal Junction Adenocarcinoma, Unresectable Esophageal Adenocarcinoma, Unresectable Gastric Adenocarcinoma, Unresectable Gastroesophageal Junction Adenocarcinoma

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Study Locations

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Location	Contacts
AMG Crystal Lake - Oncology Crystal Lake, Illinois	Site Public Contact - (advocateresearch@advocate.com)
AMG Libertyville - Oncology Libertyville, Illinois	Site Public Contact - (advocateresearch@advocatehealth.com)
Abbott-Northwestern Hospital Minneapolis, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Adena Regional Medical Center Chillicothe, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
Advanced Breast Care Center PLLC Warren, Michigan
AdventHealth Littleton Littleton, Colorado
AdventHealth Parker Parker, Colorado	Site Public Contact - (research.institute@adventhealth.com)
AdventHealth Porter Denver, Colorado	Site Public Contact - (research.institute@adventhealth.com)
Advocate Christ Medical Center Oak Lawn, Illinois
Advocate Good Samaritan Hospital Downers Grove, Illinois	Site Public Contact - (Barbara.barhamand@advocatehealth.com)
Advocate Good Shepherd Hospital Barrington, Illinois
Advocate Illinois Masonic Medical Center Chicago, Illinois
Advocate Lutheran General Hospital Park Ridge, Illinois
Advocate Outpatient Center - Aurora Aurora, Illinois	Site Public Contact - (ncorp@aah.org)
Advocate Sherman Hospital Elgin, Illinois
Advocate South Suburban Hospital Hazel Crest, Illinois
Alaska Breast Care and Surgery LLC Anchorage, Alaska	Site Public Contact - (AKPAMC.OncologyResearchSupport@providence.org)
Alaska Oncology and Hematology LLC Anchorage, Alaska	Site Public Contact - (AKPAMC.OncologyResearchSupport@providence.org)
Alaska Women's Cancer Care Anchorage, Alaska	Site Public Contact - (AKPAMC.OncologyResearchSupport@providence.org)
Alegent Health Bergan Mercy Medical Center Omaha, Nebraska
Alegent Health Immanuel Medical Center Omaha, Nebraska
Alegent Health Lakeside Hospital Omaha, Nebraska
Alegent Health Mercy Hospital Council Bluffs, Iowa
Alliance for Childhood Diseases/Cure 4 the Kids Foundation Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
Alta Bates Summit Medical Center-Herrick Campus Berkeley, California	Site Public Contact - (clinicalresearch@sutterhealth.org)
Anchorage Associates in Radiation Medicine Anchorage, Alaska	Site Public Contact - (AKPAMC.OncologyResearchSupport@providence.org)
Anchorage Oncology Centre Anchorage, Alaska
Anchorage Radiation Therapy Center Anchorage, Alaska
Ann M Wierman MD LTD Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
Armes Family Cancer Center Findlay, Ohio
Aspirus Cancer Care - James Beck Cancer Center Rhinelander, Wisconsin	Site Public Contact - (Beth.Knetter@aspirus.org)
Aspirus Cancer Care - Stevens Point Stevens Point, Wisconsin	Site Public Contact - (Beth.Knetter@aspirus.org)
Aspirus Cancer Care - Wisconsin Rapids Wisconsin Rapids, Wisconsin
Aspirus Medford Hospital Medford, Wisconsin	Site Public Contact - (Beth.Knetter@aspirus.org)
Aspirus Regional Cancer Center Wausau, Wisconsin
Asplundh Cancer Pavilion Willow Grove, Pennsylvania	Site Public Contact - (ONCTrialNow@jefferson.edu)
Atrium Medical Center-Middletown Regional Hospital Franklin, Ohio	Site Public Contact - (clinical.trials@daytonncorp.org)
Aurora Bay Area Medical Group-Marinette Marinette, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Aurora BayCare Medical Center Green Bay, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Aurora Cancer Care-Grafton Grafton, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Aurora Cancer Care-Kenosha South Kenosha, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Aurora Cancer Care-Milwaukee Milwaukee, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Aurora Cancer Care-Milwaukee West Wauwatosa, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Aurora Cancer Care-Racine Racine, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Aurora Cancer Care-Southern Lakes VLCC Burlington, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Aurora Health Care Germantown Health Center Germantown, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Aurora Medical Center in Summit Summit, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Aurora Saint Luke's Medical Center Milwaukee, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Aurora Saint Luke's South Shore Cudahy, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Aurora Sinai Medical Center Milwaukee, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Aurora West Allis Medical Center West Allis, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Avera Cancer Institute Sioux Falls, South Dakota	Site Public Contact - (OncRegulatory@avera.org)
Avera Cancer Institute - Mitchell Mitchell, South Dakota	Site Public Contact - (OncRegulatory@avera.org)
Avera Cancer Institute at Pierre Pierre, South Dakota	Site Public Contact - (OncRegulatory@avera.org)
Avera Cancer Institute at Yankton Yankton, South Dakota	Site Public Contact - (OncRegulatory@avera.org)
Avera Cancer Institute-Aberdeen Aberdeen, South Dakota	Site Public Contact - (oncregulatory@avera.org)
BASS Medical Group - Lennon Walnut Creek, California
BJC Outpatient Center at Sunset Hills Sunset Hills, Missouri
Bay Area Hospital Coos Bay, Oregon	Site Public Contact - (cherie.cox@bayareahospital.org)
Beebe Health Campus Rehoboth Beach, Delaware	Site Public Contact - (research@beebehealthcare.org)
Beebe Medical Center Lewes, Delaware	Site Public Contact - (research@beebehealthcare.org)
Beebe South Coastal Health Campus Millville, Delaware	Site Public Contact - (research@beebehealthcare.org)
Benefis Sletten Cancer Institute Great Falls, Montana	Site Public Contact - (mccinfo@mtcancer.org)
Bethesda North Hospital Cincinnati, Ohio
Bhadresh Nayak MD PC-Sterling Heights Sterling Heights, Michigan
Billings Clinic Cancer Center Billings, Montana	Site Public Contact - (research@billingsclinic.org)
Billings Clinic-Cody Cody, Wyoming	Site Public Contact - (research@billingsclinic.org)
Blanchard Valley Hospital Findlay, Ohio
Boston Medical Center Boston, Massachusetts
Boulder Community Foothills Hospital Boulder, Colorado
Bozeman Health Deaconess Hospital Bozeman, Montana	Site Public Contact - (mccinfo@mtcancer.org)
CARTI Cancer center Little Rock, Arkansas	Site Public Contact - (Research@CARTI.com)
CHI Health Good Samaritan Kearney, Nebraska
CHI Health Saint Francis Grand Island, Nebraska
California Pacific Medical Center-Pacific Campus San Francisco, California	Site Public Contact - (clinicalresearch@sutterhealth.org)
Cambridge Medical Center Cambridge, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Cancer Care Associates PC Royal Oak, Michigan
Cancer Care Center of O'Fallon O'Fallon, Illinois	Site Public Contact - (morganthaler.jodi@mhsil.com)
Cancer Care Northwest - Spokane South Spokane, Washington	Site Public Contact - (research@ccnw.net)
Cancer Care Northwest-North Spokane Spokane, Washington	Site Public Contact - (research@ccnw.net)
Cancer Care Specialists of Illinois - Decatur Decatur, Illinois	Site Public Contact - (morganthaler.jodi@mhsil.com)
Cancer Care and Hematology-Fort Collins Fort Collins, Colorado	Site Public Contact - (protocols@AllianceNCTN.org)
Cancer Center at Saint Joseph's Phoenix, Arizona
Cancer Center of Colorado at Sloan's Lake Denver, Colorado
Cancer Center of Western Wisconsin New Richmond, Wisconsin	Site Public Contact - (mmcorc@healthpartners.com)
Cancer Center-Metro Medical Center Bayamon Bayamón,
Cancer Hematology Centers - Flint Flint, Michigan	Site Public Contact - (wstrong@ghci.org)
Cancer and Blood Specialists-Henderson Henderson, Nevada	Site Public Contact - (research@sncrf.org)
Carle Cancer Center Urbana, Illinois	Site Public Contact - (Research@carle.com)
Carle Cancer Institute Normal Normal, Illinois	Site Public Contact - (Research@Carle.com)
Carle Physician Group-Effingham Effingham, Illinois	Site Public Contact - (Research@carle.com)
Carle Physician Group-Mattoon/Charleston Mattoon, Illinois	Site Public Contact - (Research@carle.com)
Carle at The Riverfront Danville, Illinois	Site Public Contact - (Research@Carle.com)
Caro Cancer Center Caro, Michigan
Carson Tahoe Regional Medical Center Carson City, Nevada	Site Public Contact - (research@sncrf.org)
Castle Medical Center Kailua, Hawaii
Centra Alan B Pearson Regional Cancer Center Lynchburg, Virginia	Site Public Contact - (Kevin.Patel@centrahealth.com)
Central Care Cancer Center - Bolivar Bolivar, Missouri	Site Public Contact - (aroland@kccop.org)
Central Care Cancer Center - Garden City Garden City, Kansas	Site Public Contact - (aroland@kccop.org)
Central Care Cancer Center - Great Bend Great Bend, Kansas	Site Public Contact - (aroland@kccop.org)
Central Ohio Breast and Endocrine Surgery Gahanna, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
Central Vermont Medical Center/National Life Cancer Treatment Berlin Corners, Vermont
Centralia Oncology Clinic Centralia, Illinois	Site Public Contact - (morganthaler.jodi@mhsil.com)
Centro Comprensivo de Cancer de UPR San Juan,	Site Public Contact - (ctsucontact@westat.com)
Chelsea Hospital Chelsea, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
Cheyenne Regional Medical Center-West Cheyenne, Wyoming
Christiana Care - Union Hospital Elkton, Maryland	Site Public Contact - (frank.crum@christianacare.org)
Christiana Care Health System-Christiana Hospital Newark, Delaware	Site Public Contact - (lbarone@christianacare.org)
Christiana Care Health System-Concord Health Center Chadds Ford, Pennsylvania	Site Public Contact - (lbarone@christianacare.org)
Christiana Care Health System-Wilmington Hospital Wilmington, Delaware	Site Public Contact - (lbarone@christianacare.org)
Clackamas Radiation Oncology Center Clackamas, Oregon	Site Public Contact - (CanRsrchStudies@providence.org)
Cleveland Clinic Mercy Hospital Canton, Ohio
Clinton Memorial Hospital/Foster J Boyd Regional Cancer Center Wilmington, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
Coborn Cancer Center at Saint Cloud Hospital Saint Cloud, Minnesota	Site Public Contact - (coborncancercenter@centracare.com)
Colorado Blood Cancer Institute Denver, Colorado
Columbus Oncology and Hematology Associates Dublin, Ohio
Columbus Oncology and Hematology Associates Inc Columbus, Ohio
CommonSpirit Cancer Center Mercy Durango, Colorado
Commonwealth Cancer Center-Corbin Corbin, Kentucky
Community Hospital of Anaconda Anaconda, Montana	Site Public Contact - (mccinfo@mtcancer.org)
Community Medical Center Missoula, Montana	Site Public Contact - (mccinfo@mtcancer.org)
Community Medical Center Missoula, Montana	Site Public Contact - (HemonCCTrials@geisinger.edu)
Comprehensive Cancer Centers of Nevada Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
Comprehensive Cancer Centers of Nevada - Central Valley Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
Comprehensive Cancer Centers of Nevada - Henderson Henderson, Nevada	Site Public Contact - (research@sncrf.org)
Comprehensive Cancer Centers of Nevada - Northwest Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
Comprehensive Cancer Centers of Nevada - Town Center Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
Comprehensive Cancer Centers of Nevada-Horizon Ridge Henderson, Nevada	Site Public Contact - (research@sncrf.org)
Comprehensive Cancer Centers of Nevada-Southeast Henderson Henderson, Nevada	Site Public Contact - (research@sncrf.org)
Comprehensive Cancer Centers of Nevada-Summerlin Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
Comprehensive Medical Center PLLC Royal Oak, Michigan
Condell Memorial Hospital Libertyville, Illinois	Site Public Contact - (advocateresearch@advocatehealth.com)
Contra Costa Regional Medical Center Martinez, California
Corewell Health Beaumont Troy Hospital Troy, Michigan
Corewell Health Dearborn Hospital Dearborn, Michigan
Corewell Health Farmington Hills Hospital Farmington Hills, Michigan
Corewell Health William Beaumont University Hospital Royal Oak, Michigan
Cox Cancer Center Branson Branson, Missouri
CoxHealth South Hospital Springfield, Missouri
Creighton University Medical Center Omaha, Nebraska
Crossroads Cancer Center Effingham, Illinois	Site Public Contact - (morganthaler.jodi@mhsil.com)
Dana Farber-Merrimack Valley Methuen, Massachusetts
Dana-Farber Cancer Institute Boston, Massachusetts
Dana-Farber Cancer Institute at Boston Medical Center - Brighton Brighton, Massachusetts
Dana-Farber Cancer Institute at Foxborough Foxborough, Massachusetts
Dana-Farber/Brigham and Women's Cancer Center at Milford Regional Milford, Massachusetts
Dana-Farber/Brigham and Women's Cancer Center at South Shore South Weymouth, Massachusetts
Dayton Physician LLC - Englewood Dayton, Ohio
Dayton Physicians LLC - Troy Troy, Ohio
Dayton Physicians LLC-Atrium Franklin, Ohio
Dayton Physicians LLC-Miami Valley South Centerville, Ohio
Dayton Physicians LLC-Wayne Greenville, Ohio
Decatur Memorial Hospital Decatur, Illinois	Site Public Contact - (morganthaler.jodi@mhsil.com)
Delaware Clinical and Laboratory Physicians PA Newark, Delaware
Delaware Health Center-Grady Cancer Center Delaware, Ohio
Doctors Cancer Center Manatí,
Doctors Hospital Columbus, Ohio
Dublin Methodist Hospital Dublin, Ohio
Duluth Clinic Ashland Ashland, Wisconsin	Site Public Contact - (CancerTrials@EssentiaHealth.org)
East Carolina University Greenville, North Carolina	Site Public Contact - (eubankss@ecu.edu)
Eden Hospital Medical Center Castro Valley, California	Site Public Contact - (clinicalresearch@sutterhealth.org)
Einstein Medical Center Philadelphia Philadelphia, Pennsylvania
Eisenhower Medical Center Rancho Mirage, California
Essentia Health - Baxter Clinic Baxter, Minnesota
Essentia Health - Deer River Clinic Deer River, Minnesota	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Essentia Health - Ely Clinic Ely, Minnesota
Essentia Health - Fosston Fosston, Minnesota	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Essentia Health - International Falls Clinic International Falls, Minnesota
Essentia Health - Jamestown Clinic Jamestown, North Dakota	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Essentia Health - Moose Lake Clinic Moose Lake, Minnesota
Essentia Health - Park Rapids Park Rapids, Minnesota	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Essentia Health - Saint Joseph's Crosslake Clinic Crosslake, Minnesota
Essentia Health - Saint Joseph's Pequot Lakes Clinic Pequot Lakes, Minnesota
Essentia Health - Saint Joseph's Pine River Clinic Pine River, Minnesota
Essentia Health - Saint Joseph's Staples Clinic Staples, Minnesota
Essentia Health Cancer Center Duluth, Minnesota	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Essentia Health Cancer Center-South University Clinic Fargo, North Dakota	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Essentia Health Hibbing Clinic Hibbing, Minnesota
Essentia Health Saint Joseph's Medical Center Brainerd, Minnesota	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Essentia Health Saint Mary's - Detroit Lakes Clinic Detroit Lakes, Minnesota	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Essentia Health Saint Mary's Hospital - Superior Superior, Wisconsin
Essentia Health Saint Mary's Medical Center Duluth, Minnesota	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Essentia Health Sandstone Sandstone, Minnesota	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Essentia Health Virginia Clinic Virginia, Minnesota	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Essentia Health-Hayward Clinic Hayward, Wisconsin	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Essentia Health-Spooner Clinic Spooner, Wisconsin	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Fairbanks Memorial Hospital Fairbanks, Alaska
Fairfield Medical Center Lancaster, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
Fairview Clinics and Surgery Center Maple Grove Maple Grove, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Fairview Lakes Medical Center Wyoming, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Fairview Northland Medical Center Princeton, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Fairview Ridges Hospital Burnsville, Minnesota
Fairview Southdale Hospital Edina, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Farmington Health Center Farmington, Utah	Site Public Contact - (cancerinfo@hci.utah.edu)
FirstHealth of the Carolinas-Moore Regional Hospital Pinehurst, North Carolina	Site Public Contact - (jcwilliams@firsthealth.org)
Flaget Memorial Hospital Bardstown, Kentucky
Freeman Health System Joplin, Missouri	Site Public Contact - (LJCrockett@freemanhealth.com)
Freeman Physician Group of Pittsburg Pittsburg, Kansas	Site Public Contact - (BNMathew@freemanhealth.com)
Fresno Cancer Center Fresno, California	Site Public Contact - (Kpoct@kp.org)
Geisinger Cancer Center Dickson City Dickson City, Pennsylvania	Site Public Contact - (hemoncctrials@geisinger.edu)
Geisinger Cancer Services-Pottsville Pottsville, Pennsylvania	Site Public Contact - (HemonCCTrials@geisinger.edu)
Geisinger Medical Center Danville, Pennsylvania	Site Public Contact - (HemonCCTrials@geisinger.edu)
Geisinger Medical Center-Cancer Center Hazleton Hazleton, Pennsylvania	Site Public Contact - (HemonCCTrials@geisinger.edu)
Geisinger Medical Oncology-Lewisburg Lewisburg, Pennsylvania	Site Public Contact - (HemonCCTrials@geisinger.edu)
Geisinger Wyoming Valley/Henry Cancer Center Wilkes-Barre, Pennsylvania	Site Public Contact - (HemonCCTrials@geisinger.edu)
Genesee Hematology Oncology PC Flint, Michigan	Site Public Contact - (wstrong@ghci.org)
Genesis Healthcare System Cancer Care Center Zanesville, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
Genesys Hurley Cancer Institute Flint, Michigan	Site Public Contact - (wstrong@ghci.org)
George Washington University Medical Center Washington D.C., District of Columbia
Glens Falls Hospital Glens Falls, New York
Good Samaritan Hospital - Cancer Centers of Colorado Lafayette, Colorado	Site Public Contact - (peaksresearch@imail.org)
Good Samaritan Hospital - Cincinnati Cincinnati, Ohio
Grady Memorial Hospital Delaware, Ohio
Grant Medical Center Columbus, Ohio
Great Falls Clinic Great Falls, Montana	Site Public Contact - (mccinfo@mtcancer.org)
Greater Dayton Cancer Center Kettering, Ohio
Gundersen Lutheran Medical Center La Crosse, Wisconsin	Site Public Contact - (cancerctr@gundersenhealth.org)
HSHS Saint Elizabeth's Hospital O'Fallon, Illinois	Site Public Contact - (morganthaler.jodi@mhsil.com)
Hartford HealthCare - Avon Avon, Connecticut
Hartford HealthCare - Manchester Manchester, Connecticut
Hartford Hospital Hartford, Connecticut
Hawaii Cancer Care - Westridge ‘Aiea, Hawaii	Site Public Contact - (info@hawaiicancercare.com)
Hawaii Cancer Care Inc - Waterfront Plaza Honolulu, Hawaii	Site Public Contact - (i.webster@hawaiicancercare.com)
Hawaii Diagnostic Radiology Services LLC Honolulu, Hawaii	Site Public Contact - (mmiyoshi@hawaiidrs.com)
HaysMed Hays, Kansas
Health Partners Inc Minneapolis, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Heartland Oncology and Hematology LLP Council Bluffs, Iowa
Heartland Regional Medical Center Saint Joseph, Missouri	Site Public Contact - (Trisha.England2@mymlc.com)
Helen F Graham Cancer Center Newark, Delaware	Site Public Contact - (lbarone@christianacare.org)
Hematology Oncology Consultants PC-Royal Oak Royal Oak, Michigan
Hematology Oncology Consultants PC-Troy Troy, Michigan
Hematology Oncology Consultants-Clarkston Clarkston, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
Hennepin County Medical Center Minneapolis, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Henry Ford Health Saint John Hospital Detroit, Michigan	Site Public Contact - (Kkeenan1@hfhs.org)
Henry Ford Health Warren Hospital Warren, Michigan	Site Public Contact - (kforman1@hfhs.org)
Henry Ford Madison Heights Hospital - Breast Warren, Michigan	Site Public Contact - (kforman1@hfhs.org)
Henry Ford River District Hospital East China Township, Michigan	Site Public Contact - (kforman1@hfhs.org)
Henry Ford Saint John Hospital - Academic Grosse Pointe Woods, Michigan	Site Public Contact - (kforman1@hfhs.org)
Henry Ford Saint John Hospital - Breast Grosse Pointe Woods, Michigan	Site Public Contact - (karen.forman@ascension.org)
Henry Ford Saint John Hospital - Macomb Medical Macomb, Michigan	Site Public Contact - (kforman1@hfhs.org)
Henry Ford Saint John Hospital - Van Elslander Grosse Pointe Woods, Michigan	Site Public Contact - (kforman1@hfhs.org)
Henry Ford Warren Hospital - Breast Macomb Macomb, Michigan	Site Public Contact - (kforman1@hfhs.org)
Henry Ford Warren Hospital - GLCMS Warren, Michigan	Site Public Contact - (kforman1@hfhs.org)
Hi-Line Sletten Cancer Center Havre, Montana	Site Public Contact - (protocols@AllianceNCTN.org)
Hickman Cancer Center Adrian, Michigan
Holy Cross Hospital Fort Lauderdale, Florida	Site Public Contact - (eileen.georgi@holy-cross.com)
Hope Cancer Care of Nevada Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
Hope Cancer Care of Nevada-Pahrump Pahrump, Nevada	Site Public Contact - (research@sncrf.org)
Hope Cancer Center Pontiac, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
Huntsman Cancer Institute/University of Utah Salt Lake City, Utah	Site Public Contact - (cancerinfo@hci.utah.edu)
Hurley Medical Center Flint, Michigan	Site Public Contact - (wstrong@ghci.org)
Huron Gastroenterology PC Ypsilanti, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
Idaho Urologic Institute-Meridian Meridian, Idaho	Site Public Contact - (stephanie.couch@stjoeshealth.org)
Illinois CancerCare - Washington Washington, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Bloomington Bloomington, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Canton Canton, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Carthage Carthage, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Dixon Dixon, Illinois
Illinois CancerCare-Eureka Eureka, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Galesburg Galesburg, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Kewanee Clinic Kewanee, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Macomb Macomb, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Ottawa Clinic Ottawa, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Pekin Pekin, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Peoria Peoria, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Peru Peru, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Princeton Princeton, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Indu and Raj Soin Medical Center Beavercreek, Ohio
Ingalls Memorial Hospital Harvey, Illinois	Site Public Contact - (clinicaltrials@ingalls.org)
Inova Fairfax Hospital Falls Church, Virginia	Site Public Contact - (Stephanie.VanBebber@inova.org)
Inova Schar Cancer Institute Fairfax, Virginia	Site Public Contact - (Stephanie.VanBebber@inova.org)
Intermountain Health Lutheran Hospital Wheat Ridge, Colorado	Site Public Contact - (peaksresearch@imail.org)
Intermountain Health Platte Valley Hospital Brighton, Colorado	Site Public Contact - (peaksresearch@imail.org)
Iowa Methodist Medical Center Des Moines, Iowa
Jefferson Cherry Hill Hospital Cherry Hill, New Jersey	Site Public Contact - (ONCTrialNow@jefferson.edu)
Jefferson Healthcare Port Townsend, Washington
John H Stroger Jr Hospital of Cook County Chicago, Illinois
Johns Hopkins University/Sidney Kimmel Cancer Center Baltimore, Maryland	Site Public Contact - (jhcccro@jhmi.edu)
Jupiter Medical Center Jupiter, Florida	Site Public Contact - (clinicaltrials@jupitermed.com)
Kadlec Clinic Hematology and Oncology Kennewick, Washington	Site Public Contact - (research@kadlecmed.org)
Kaiser Permanente Cancer Treatment Center South San Francisco, California	Site Public Contact - (Kpoct@kp.org)
Kaiser Permanente Downtown Commons Sacramento, California	Site Public Contact - (kpoct@kp.org)
Kaiser Permanente Dublin Dublin, California
Kaiser Permanente Fresno Orchard Plaza Fresno, California
Kaiser Permanente Medical Center - Santa Clara Santa Clara, California	Site Public Contact - (Kpoct@kp.org)
Kaiser Permanente Medical Center-Vacaville Vacaville, California	Site Public Contact - (Kpoct@kp.org)
Kaiser Permanente Moanalua Medical Center Honolulu, Hawaii	Site Public Contact - (shelley.a.clark@kp.org)
Kaiser Permanente Oakland-Broadway Oakland, California	Site Public Contact - (Kpoct@kp.org)
Kaiser Permanente San Leandro San Leandro, California	Site Public Contact - (Kpoct@kp.org)
Kaiser Permanente- Marshall Medical Offices Redwood City, California
Kaiser Permanente-Deer Valley Medical Center Antioch, California	Site Public Contact - (Kpoct@kp.org)
Kaiser Permanente-Fremont Fremont, California	Site Public Contact - (Kpoct@kp.org)
Kaiser Permanente-Fresno Fresno, California	Site Public Contact - (Kpoct@kp.org)
Kaiser Permanente-Modesto Modesto, California	Site Public Contact - (Kpoct@kp.org)
Kaiser Permanente-Oakland Oakland, California	Site Public Contact - (Kpoct@kp.org)
Kaiser Permanente-Rancho Cordova Cancer Center Rancho Cordova, California	Site Public Contact - (Kpoct@kp.org)
Kaiser Permanente-Richmond Richmond, California	Site Public Contact - (Kpoct@kp.org)
Kaiser Permanente-Roseville Roseville, California	Site Public Contact - (Kpoct@kp.org)
Kaiser Permanente-San Francisco San Francisco, California	Site Public Contact - (Kpoct@kp.org)
Kaiser Permanente-Santa Rosa Santa Rosa, California	Site Public Contact - (Kpoct@kp.org)
Kaiser Permanente-Santa Teresa-San Jose San Jose, California	Site Public Contact - (Kpoct@kp.org)
Kaiser Permanente-South Sacramento Sacramento, California	Site Public Contact - (Kpoct@kp.org)
Kaiser Permanente-South San Francisco South San Francisco, California	Site Public Contact - (Kpoct@kp.org)
Kaiser Permanente-Stockton Stockton, California	Site Public Contact - (Kpoct@kp.org)
Kaiser Permanente-Vallejo Vallejo, California	Site Public Contact - (Kpoct@kp.org)
Kaiser Permanente-Walnut Creek Walnut Creek, California	Site Public Contact - (Kpoct@kp.org)
Kaiser San Rafael-Gallinas San Rafael, California	Site Public Contact - (Kpoct@kp.org)
Kapiolani Medical Center for Women and Children Honolulu, Hawaii
Karmanos Cancer Institute at McLaren Greater Lansing Lansing, Michigan	Site Public Contact - (ctoadmin@karmanos.org)
Katmai Oncology Group Anchorage, Alaska	Site Public Contact - (AKPAMC.OncologyResearchSupport@providence.org)
Keck Medicine of USC Koreatown Los Angeles, California
Kettering Medical Center Kettering, Ohio
Kingman Regional Medical Center Kingman, Arizona	Site Public Contact - (research@sncrf.org)
Knox Community Hospital Mount Vernon, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
Kootenai Clinic Cancer Services - Post Falls Post Falls, Idaho	Site Public Contact - (mccinfo@mtcancer.org)
Kootenai Clinic Cancer Services - Sandpoint Sandpoint, Idaho	Site Public Contact - (mccinfo@mtcancer.org)
Kootenai Health - Coeur d'Alene Coeur d'Alene, Idaho	Site Public Contact - (mccinfo@mtcancer.org)
Kuakini Medical Center Honolulu, Hawaii
Lake Regional Hospital Osage Beach, Missouri	Site Public Contact - (clinicaltrials@lakeregional.com)
Lakeview Hospital Stillwater, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Langlade Hospital and Cancer Center Antigo, Wisconsin	Site Public Contact - (Juli.Alford@aspirus.org)
Las Vegas Cancer Center-Henderson Henderson, Nevada
Las Vegas Cancer Center-Medical Center Las Vegas, Nevada
Las Vegas Prostate Cancer Center Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
Las Vegas Urology - Cathedral Rock Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
Las Vegas Urology - Green Valley Henderson, Nevada	Site Public Contact - (research@sncrf.org)
Las Vegas Urology - Pebble Henderson, Nevada	Site Public Contact - (research@sncrf.org)
Las Vegas Urology - Pecos Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
Las Vegas Urology - Smoke Ranch Las Vegas, Nevada	Site Public Contact - (research@smcrf.org)
Las Vegas Urology - Sunset Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
Lawrence Memorial Hospital Lawrence, Kansas	Site Public Contact - (Stephanie.Norris@LMH.ORG)
Lehigh Valley Hospital - Muhlenberg Bethlehem, Pennsylvania	Site Public Contact - (Morgan_M.Horton@lvhn.org)
Lehigh Valley Hospital-Cedar Crest Allentown, Pennsylvania	Site Public Contact - (Morgan_M.Horton@lvhn.org)
Lehigh Valley Hospital-Hazleton Hazleton, Pennsylvania	Site Public Contact - (Morgan_M.Horton@lvhn.org)
Lenox Hill Hospital New York, New York
Licking Memorial Hospital Newark, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
Logan Health Medical Center Kalispell, Montana	Site Public Contact - (mccinfo@mtcancer.org)
Longmont United Hospital Longmont, Colorado
Los Angeles General Medical Center Los Angeles, California	Site Public Contact - (uscnorrisinfo@med.usc.edu)
Lutheran Hospital - Cancer Centers of Colorado Golden, Colorado	Site Public Contact - (peaksresearch@imail.org)
MU Health Care Goldschmidt Cancer Center Jefferson City, Missouri
Macomb Hematology Oncology PC Warren, Michigan
Manhattan Eye Ear and Throat Hospital New York, New York
Marietta Memorial Hospital Marietta, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
Marshfield Clinic - Wisconsin Rapids Center Wisconsin Rapids, Wisconsin	Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org)
Marshfield Clinic-Chippewa Center Chippewa Falls, Wisconsin	Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org)
Marshfield Clinic-Wausau Center Wausau, Wisconsin	Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org)
Marshfield Medical Center - Ladysmith Ladysmith, Wisconsin	Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org)
Marshfield Medical Center - Minocqua Minocqua, Wisconsin	Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org)
Marshfield Medical Center - Neillsville Neillsville, Wisconsin	Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org)
Marshfield Medical Center - Weston Weston, Wisconsin	Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org)
Marshfield Medical Center-EC Cancer Center Eau Claire, Wisconsin	Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org)
Marshfield Medical Center-Marshfield Marshfield, Wisconsin	Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org)
Marshfield Medical Center-Rice Lake Rice Lake, Wisconsin	Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org)
Marshfield Medical Center-River Region at Stevens Point Stevens Point, Wisconsin	Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org)
Mary Greeley Medical Center Ames, Iowa
McFarland Clinic - Ames Ames, Iowa	Site Public Contact - (ksoder@mcfarlandclinic.com)
McFarland Clinic - Boone Boone, Iowa
McFarland Clinic - Jefferson Jefferson, Iowa
McFarland Clinic - Marshalltown Marshalltown, Iowa
McFarland Clinic - Trinity Cancer Center Fort Dodge, Iowa
McLaren Cancer Institute-Bay City Bay City, Michigan	Site Public Contact - (ctoadmin@karmanos.org)
McLaren Cancer Institute-Clarkston Clarkston, Michigan	Site Public Contact - (ctoadmin@karmanos.org)
McLaren Cancer Institute-Flint Flint, Michigan	Site Public Contact - (ctoadmin@karmanos.org)
McLaren Cancer Institute-Lapeer Region Lapeer, Michigan	Site Public Contact - (ctoadmin@karmanos.org)
McLaren Cancer Institute-Macomb Mount Clemens, Michigan	Site Public Contact - (ctoadmin@karmanos.org)
McLaren Cancer Institute-Northern Michigan Petoskey, Michigan	Site Public Contact - (ctoadmin@karmanos.org)
McLaren-Port Huron Port Huron, Michigan	Site Public Contact - (ctoadmin@karmanos.org)
MedStar Georgetown University Hospital Washington D.C., District of Columbia
Medical Center of the Rockies Loveland, Colorado
Medical Oncology Hematology Consultants PA Newark, Delaware	Site Public Contact - (lbarone@christianacare.org)
Medical University of South Carolina Charleston, South Carolina	Site Public Contact - (hcc-clinical-trials@musc.edu)
Memorial Hospital Chattanooga, Tennessee	Site Public Contact - (Jeffh@columbusccop.org)
Memorial Hospital North Colorado Springs, Colorado
Memorial Hospital West Pembroke Pines, Florida
Memorial Hospital of Carbondale Carbondale, Illinois	Site Public Contact - (clinical.research@sih.net)
Memorial Medical Center Modesto, California	Site Public Contact - (clinicalresearch@sutterhealth.org)
Memorial Regional Hospital/Joe DiMaggio Children's Hospital Hollywood, Florida	Site Public Contact - (OHR@mhs.net)
Mercy Cancer Center Merced, California
Mercy Cancer Center - Cape Girardeau Cape Girardeau, Missouri
Mercy Cancer Center - Carmichael Carmichael, California
Mercy Cancer Center - Elk Grove Elk Grove, California
Mercy Cancer Center - Rocklin Rocklin, California
Mercy Cancer Center - Sacramento Sacramento, California
Mercy Clinic-Rolla-Cancer and Hematology Rolla, Missouri
Mercy Health - Paducah Cancer Center Paducah, Kentucky
Mercy Health - Perrysburg Hospital Perrysburg, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
Mercy Health - Saint Anne Hospital Toledo, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
Mercy Health - Saint Vincent Hospital Toledo, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
Mercy Health Sylvania Radiation Oncology Center Toledo, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
Mercy Hospital Coon Rapids, Minnesota
Mercy Hospital Coon Rapids, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Mercy Hospital Fort Smith Fort Smith, Arkansas
Mercy Hospital Joplin Joplin, Missouri	Site Public Contact - (esmeralda.carrillo@mercy.net)
Mercy Hospital Oklahoma City Oklahoma City, Oklahoma
Mercy Hospital Pittsburg Pittsburg, Kansas
Mercy Hospital Saint Louis St Louis, Missouri
Mercy Hospital South St Louis, Missouri	Site Public Contact - (Danielle.Werle@mercy.net)
Mercy Hospital Springfield Springfield, Missouri
Mercy Hospital Washington Washington, Missouri
Mercy Infusion Center - Chippewa St Louis, Missouri
Mercy Medical Center Springfield, Massachusetts
Mercy Oncology and Hematology - Clayton-Clarkson Ballwin, Missouri
Mercy San Juan Medical Center Carmichael, California
Methodist Jennie Edmundson Hospital Council Bluffs, Iowa	Site Public Contact - (kathryn.bartz@nmhs.org)
Methodist Medical Center of Illinois Peoria, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Miami Valley Cancer Care and Infusion Greenville, Ohio
Miami Valley Hospital Dayton, Ohio	Site Public Contact - (clinical.trials@daytonncorp.org)
Miami Valley Hospital North Dayton, Ohio	Site Public Contact - (clinical.trials@daytonncorp.org)
Miami Valley Hospital South Centerville, Ohio	Site Public Contact - (clinical.trials@daytonncorp.org)
Michigan Healthcare Professionals Pontiac Pontiac, Michigan	Site Public Contact - (Emily.Crofts@trinity-health.org)
Michigan Institute of Urology-Town Center Troy, Michigan
Midlands Community Hospital Papillion, Nebraska
Midstate Medical Center Meriden, Connecticut
Miller-Dwan Hospital Duluth, Minnesota	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Mills Health Center San Mateo, California	Site Public Contact - (clinicalresearch@sutterhealth.org)
Mills-Peninsula Medical Center Burlingame, California	Site Public Contact - (clinicalresearch@sutterhealth.org)
Minnesota Oncology - Burnsville Burnsville, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Minnesota Oncology Hematology PA-Maplewood Maplewood, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Minnesota Oncology Hematology PA-Woodbury Woodbury, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Mission Hope Medical Oncology - Arroyo Grande Arroyo Grande, California
Mission Hope Medical Oncology - Santa Maria Santa Maria, California
Missouri Baptist Medical Center St Louis, Missouri
Missouri Baptist Sullivan Hospital Sullivan, Missouri
Montefiore Medical Center-Einstein Campus The Bronx, New York	Site Public Contact - (eskwak@montefiore.org)
Montefiore Medical Center-Weiler Hospital The Bronx, New York	Site Public Contact - (eskwak@montefiore.org)
Monticello Cancer Center Monticello, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Mount Carmel East Hospital Columbus, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
Mount Carmel Grove City Hospital Grove City, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
Mount Carmel Health Center West Columbus, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
Mount Carmel New Albany Surgical Hospital New Albany, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
Mount Sinai Comprehensive Cancer Center at Aventura Aventura, Florida	Site Public Contact - (yenrique@msmc.com)
Mount Sinai Hospital Medical Center Chicago, Illinois	Site Public Contact - (suhi@sinai.org)
Mount Sinai Medical Center Miami Beach, Florida	Site Public Contact - (yenrique@msmc.com)
Mountain Blue Cancer Care Center - Swedish Englewood, Colorado
MyMichigan Medical Center Alpena Alpena, Michigan	Site Public Contact - (CVResearch@mymichigan.org)
MyMichigan Medical Center Gladwin Gladwin, Michigan	Site Public Contact - (CVResearch@mymichigan.org)
MyMichigan Medical Center Gratiot Alma, Michigan	Site Public Contact - (CVResearch@mymichigan.org)
MyMichigan Medical Center Midland Midland, Michigan	Site Public Contact - (CVResearch@mymichigan.org)
MyMichigan Medical Center Mount Pleasant Mount Pleasant, Michigan	Site Public Contact - (CVResearch@mymichigan.org)
MyMichigan Medical Center Saginaw Saginaw, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
MyMichigan Medical Center Tawas Tawas City, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center New York, New York	Site Public Contact - (cancerclinicaltrials@cumc.columbia.edu)
NYP/Weill Cornell Medical Center New York, New York
National Jewish Health-Main Campus Denver, Colorado	Site Public Contact - (glicht@co-cancerresearch.org)
National Jewish Health-Northern Hematology Oncology Thornton, Colorado	Site Public Contact - (glicht@co-cancerresearch.org)
National Jewish Health-Western Hematology Oncology Golden, Colorado	Site Public Contact - (glicht@co-cancerresearch.org)
Nebraska Cancer Specialists/Oncology Hematology West PC - MECC Omaha, Nebraska
Nebraska Medicine-Bellevue Bellevue, Nebraska	Site Public Contact - (unmcrsa@unmc.edu)
Nebraska Medicine-Village Pointe Omaha, Nebraska
Nebraska Methodist Hospital Omaha, Nebraska
New Ulm Medical Center New Ulm, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
New York-Presbyterian/Brooklyn Methodist Hospital Brooklyn, New York	Site Public Contact - (Adg9003@nyp.org)
Newark Radiation Oncology Newark, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
Newland Medical Associates-Clarkston Clarkston, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
Newland Medical Associates-Pontiac Pontiac, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
North Memorial Medical Health Center Robbinsdale, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
North Star Lodge Cancer Center at Yakima Valley Memorial Hospital Yakima, Washington	Site Public Contact - (Memorial-ClinicalTrials@yvmh.org)
Northern Westchester Hospital Mount Kisco, New York	Site Public Contact - (AMellor@northwell.edu)
Northwell Health Cancer Institute at Huntington Greenlawn, New York
Northwell Health/Center for Advanced Medicine Lake Success, New York
Northwest Cancer Center - Hobart Hobart, Indiana
Northwest Cancer Center - Main Campus Crown Point, Indiana
Northwest Cancer Center - Valparaiso Valparaiso, Indiana	Site Public Contact - (CancerResearch@COMHS.org)
Northwest Oncology LLC Dyer, Indiana
Northwest Wisconsin Cancer Center Ashland, Wisconsin	Site Public Contact - (CancerTrials@EssentiaHealth.org)
OSF Saint Anthony's Health Center Alton, Illinois
OSF Saint Francis Hospital and Medical Group Escanaba, Michigan	Site Public Contact - (WI_research_admin@hshs.org)
Oakland Colon Rectal Associates Royal Oak, Michigan
Oakland Medical Group Royal Oak, Michigan
Ohio State University Comprehensive Cancer Center Columbus, Ohio	Site Public Contact - (Jamesline@osumc.edu)
OhioHealth Mansfield Hospital Mansfield, Ohio
OhioHealth Marion General Hospital Marion, Ohio
Oncology Associates PC Omaha, Nebraska
Oncology Associates at Mercy Medical Center Cedar Rapids, Iowa
Oncology Hematology Associates of Saginaw Valley PC Saginaw, Michigan
Oncology Hematology Care Inc-Kenwood Cincinnati, Ohio
Oncology Las Vegas - Henderson Henderson, Nevada	Site Public Contact - (research@sncrf.org)
Oncology Las Vegas - Tenaya Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
OptumCare Cancer Care at Charleston Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
OptumCare Cancer Care at Fort Apache Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
OptumCare Cancer Care at MountainView Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
OptumCare Cancer Care at Seven Hills Henderson, Nevada	Site Public Contact - (research@sncrf.org)
Orion Cancer Care Findlay, Ohio
Overlake Medical Center Bellevue, Washington
PCR Oncology Arroyo Grande, California	Site Public Contact - (research@sncrf.org)
PROncology San Juan,	Site Public Contact - (info@PRoncology.com)
Pacific Central Coast Health Center-San Luis Obispo San Luis Obispo, California
Pali Momi Medical Center ‘Aiea, Hawaii
Palo Alto Medical Foundation Health Care Palo Alto, California	Site Public Contact - (clinicalresearch@sutterhealth.org)
Palo Alto Medical Foundation-Camino Division Mountain View, California	Site Public Contact - (clinicalresearch@sutterhealth.org)
Palo Alto Medical Foundation-Fremont Fremont, California	Site Public Contact - (clinicalresearch@sutterhealth.org)
Palo Alto Medical Foundation-Gynecologic Oncology Mountain View, California	Site Public Contact - (clinicalresearch@sutterhealth.org)
Palo Alto Medical Foundation-Santa Cruz Santa Cruz, California	Site Public Contact - (clinicalresearch@sutterhealth.org)
Palo Alto Medical Foundation-Sunnyvale Sunnyvale, California	Site Public Contact - (clinicalresearch@sutterhealth.org)
Park Nicollet Clinic - Saint Louis Park Saint Louis Park, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Parkland Health Center - Farmington Farmington, Missouri
Parkland Memorial Hospital Dallas, Texas	Site Public Contact - (canceranswerline@UTSouthwestern.edu)
PeaceHealth Saint John Medical Center Longview, Washington	Site Public Contact - (kmakin-bond@peacehealth.org)
PeaceHealth Saint Joseph Medical Center Bellingham, Washington
PeaceHealth Southwest Medical Center Vancouver, Washington	Site Public Contact - (kmakin-bond@peacehealth.org)
PeaceHealth United General Medical Center Sedro-Woolley, Washington	Site Public Contact - (rcrompton@peacehealth.org)
Penrose-Saint Francis Healthcare Colorado Springs, Colorado
Phelps Health Delbert Day Cancer Institute Rolla, Missouri	Site Public Contact - (research@phelpshealth.org)
Phelps Memorial Hospital Center Sleepy Hollow, New York
Pocono Medical Center East Stroudsburg, Pennsylvania	Site Public Contact - (Morgan_M.Horton@lvhn.org)
Poudre Valley Hospital Fort Collins, Colorado
Premier Blood and Cancer Center Dayton, Ohio
Premier Hematology Oncology Care Sterling Heights, Michigan
Presbyterian - Saint Lukes Medical Center - Health One Denver, Colorado
ProHealth D N Greenwald Center Mukwonago, Wisconsin	Site Public Contact - (research.institute@phci.org)
ProHealth Oconomowoc Memorial Hospital Oconomowoc, Wisconsin
ProHealth Waukesha Memorial Hospital Waukesha, Wisconsin
Providence Alaska Medical Center Anchorage, Alaska	Site Public Contact - (AKPAMC.OncologyResearchSupport@providence.org)
Providence Cancer Institute Clackamas Clinic Clackamas, Oregon
Providence Hood River Memorial Hospital Hood River, Oregon	Site Public Contact - (canrsrchstudies@provdience.org)
Providence Medical Foundation - Santa Rosa Santa Rosa, California
Providence Newberg Medical Center Newberg, Oregon	Site Public Contact - (CanRsrchStudies@providence.org)
Providence Portland Medical Center Portland, Oregon	Site Public Contact - (CanRsrchStudies@providence.org)
Providence Queen of The Valley Napa, California
Providence Regional Cancer Partnership Everett, Washington	Site Public Contact - (marilyn.birchman@providence.org)
Providence Regional Cancer System-Aberdeen Aberdeen, Washington	Site Public Contact - (deidre.dillon@providence.org)
Providence Regional Cancer System-Centralia Centralia, Washington	Site Public Contact - (deidre.dillon@providence.org)
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Puerto Rico Hematology Oncology Group Bayamón,
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Tamarack Health Hayward Medical Center Hayward, Wisconsin
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The Community Hospital Munster, Indiana
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The Melanoma and Skin Cancer Institute Englewood, Colorado
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Behavioral Exercise Training to Reduce Cardiovascular Disease Risk (EXTRA-PC)

Contact(s):

Alexander R Lucas, PhD - Alexander.Lucas@vcuhealth.org

Principal Investigator:

System ID: NCT06237179

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Interventions: BEHAVIORAL: Exercise Training Intervention, BEHAVIORAL: Healthy Living Education

Conditions: Prostate Cancer, Supportive Care

Keywords: Prostate Cancer, Supportive Care, Exercise

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Location	Contacts
Richmond Veterans Affairs Medical Center Richmond, Virginia	Alexander R Lucas, PhD - (Alexander.Lucas2@va.gov) Alexandra L Marshall, MS - (lara.marshall@vcuhealth.org)
Virginia Commonwealth University Massey Cancer Center Richmond, Virginia	Alexandra Marshall - (marshallla@vcu.edu) Alexander Lucas, PhD - (Alexander.Lucas@vcuhealth.org)

Examining Lateralized Aspects of Motor Control Using Non-invasive Neural Stimulation

Contact(s):

Brooke Dexheimer, PhD, OTD, OTR/L - dexheimerb@vcu.edu

Principal Investigator:

System ID: NCT05947279

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Interventions: BEHAVIORAL: Comparing motor adaptation reaching performance

Conditions: Motor Adaptation and Generalization, Posterior Parietal Cortex, Cerebellum

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Location	Contacts
Virginia Commonwealth University Medical Center Richmond, Virginia	Brooke Dexheimer - (dexheimerb@vcu.edu)

Testing Continuous Versus Intermittent Treatment With the Study Drug Zanubrutinib for Older Patients With Previously Untreated Mantle Cell Lymphoma

Contact(s):

Anne Beaven, MD - anne_beaven@med.unc.edu

Principal Investigator:

System ID: NCT05976763

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Inclusion Criteria:

* • Histologically confirmed mantle cell lymphoma with cyclin D1 (BCL1) expression by immunohistochemical stains and/or t(11;14) by cytogenetics or fluorescence in situ hybridization (FISH) as confirmed by the enrolling center * Any stage allowed (stage I-IV) * Presence of measurable disease, defined as \>= 1 nodal lesion that is \> 1.5 cm in longest diameter or \>= 1 extranodal lesion that is \> 1 cm in longest diameter * Steroids for management of mantle cell lymphoma are allowed up to a dose of prednisone 100mg/day (or equivalent) for up to 7 days * No prior systemic treatment for mantle cell lymphoma * No prior radiation treatment for stage I MCL * No prior exposure to a BTK inhibitor or anti-CD20 monoclonal antibody * No prior stem cell transplant * Age \>= 70 years OR age \>= 60 to \< 70 years with comorbidities precluding autologous stem cell transplantation (autoSCT) including at least one of the following: a) cardiac ejection fraction (EF) \< 45%, b) diffusing capacity for carbon monoxide \< 60% predicted; c) creatinine clearance \< 70 but \> 30ml/minute (min); d) Eastern Cooperative Oncology Group (ECOG) performance status of 2, which poses an unacceptable risk of toxicity for high-dose therapy and stem cell transplantation; or e) Cumulative Illness Rating Scales (CIRS) total score \> 6 * ECOG Performance Status 0-2 * Absolute neutrophil count (ANC) \>= 750/mm\^3 (without growth factor support within 7 days) * Platelet count \>= 75,000/mm\^3 (or \>= 50,000/mm\^3 for patients with bone marrow involvement of lymphoma) without growth factor support or transfusion within 7 days * Creatinine clearance \>= 30 mL/ min determined by either: a) Estimation using the Cockcroft-Gault equation or b) Measurement by nuclear medicine scan or 24 hour urine collection * Total bilirubin =\< 1.5 x upper limit of normal (ULN) (unless documented Gilbert's syndrome) * Aspartate transferase (AST) / alanine transaminase (ALT) =\< 3 x ULN * Patients should not be considered candidates for stem cell transplant or must have declined a stem cell transplant strategy * No clinically significant cardiovascular disease including the following * Unstable angina within 3 months before registration * New York Heart Association class III or IV congestive heart failure * History of clinically significant arrhythmias (eg, sustained ventricular tachycardia, ventricular fibrillation, torsades de pointes) * QT correction formula (QTcF) \> 480 msecs based on Fredericia's formula * History of Mobitz II second-degree or third-degree heart block without a permanent pacemaker in place * Human immunodeficiency virus (HIV)-infected patients on effective anti-retroviral therapy with undetectable viral load within 6 months are eligible for this trial * No active Hepatitis B or Hepatitis C infection. Patients with prior hepatitis B virus (HBV) exposure (positive HBV core antibody and/or surface antigen) are eligible if they have no detectable viral load, and are taking appropriate prophylactic antiviral therapy to prevent reactivation. Patients with history of hepatitis C virus (HCV) are eligible if they have an undetectable HCV viral load * Patients with a prior or concurrent malignancy whose natural history or treatment does not have the potential to interfere with the safety or efficacy assessment of the investigational regimen are eligible for this trial * No history of severe bleeding disorder such as hemophilia A, hemophilia B, von Willebrand disease, or history of spontaneous bleeding requiring blood transfusion or other medical intervention * No history of stroke or intracranial hemorrhage within 6 months prior to registration * No disease significantly affecting gastrointestinal function such as malabsorption syndrome, resection of the stomach or small bowel, bariatric surgery procedures, symptomatic inflammatory bowel disease, or partial or complete bowel obstruction. Patient must be able to swallow pills * Potential trial participants should have recovered from major surgery * No vaccination with a live vaccine within 35 days prior to registration * No hypersensitivity to zanubrutinib or rituximab or any of the other ingredients of the study drugs * Chronic concomitant treatment with strong inhibitors of CYP3A4 is not allowed on this study. Patients on strong CYP3A4 inhibitors must discontinue the drug for 14 days prior to registration on the study. * Chronic concomitant treatment with strong CYP3A4 inducers is not allowed. Patients must discontinue the drug 14 days prior to the start of study treatment * Avoid use of moderate CYP3A4 inhibitors, PGP inhibitors, and moderate CYP3A4 inducers * Archival tissue must be available for submission in all patients for histopathology review, though participation in correlative substudies is optional

Interventions: DRUG: Zanubrutinib, BIOLOGICAL: Rituximab, OTHER: Patient Observation, PROCEDURE: Bone Marrow Biopsy, OTHER: Fludeoxyglucose F-18, PROCEDURE: Positron Emission Tomography, PROCEDURE: Computed Tomography, PROCEDURE: Magnetic Resonance Imaging, PROCEDURE: Esophagogastroduodenoscopy, PROCEDURE: Colonoscopy, PROCEDURE: Biospecimen Collection, OTHER: Questionnaire Administration

Conditions: Mantle Cell Lymphoma

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Location	Contacts
Abbott-Northwestern Hospital Minneapolis, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Alliance for Clinical Trials in Oncology Boston, Massachusetts	Anne W. Beaven - (beaven@med.unc.edu)
Augusta University Medical Center Augusta, Georgia	Site Public Contact - (ga_cares@augusta.edu)
Benefis Sletten Cancer Institute Great Falls, Montana	Site Public Contact - (mccinfo@mtcancer.org)
Billings Clinic Cancer Center Billings, Montana	Site Public Contact - (research@billingsclinic.org)
Bozeman Health Deaconess Hospital Bozeman, Montana	Site Public Contact - (mccinfo@mtcancer.org)
Broadlawns Medical Center Des Moines, Iowa
Cancer Care Center of O'Fallon O'Fallon, Illinois	Site Public Contact - (morganthaler.jodi@mhsil.com)
Cancer Care Specialists of Illinois - Decatur Decatur, Illinois	Site Public Contact - (morganthaler.jodi@mhsil.com)
Cancer Centers of Southwest Oklahoma Research Lawton, Oklahoma
Cancer Hematology Centers - Flint Flint, Michigan	Site Public Contact - (wstrong@ghci.org)
Carle Cancer Center Urbana, Illinois	Site Public Contact - (Research@carle.com)
Carle Physician Group-Effingham Effingham, Illinois	Site Public Contact - (Research@carle.com)
Carle Physician Group-Mattoon/Charleston Mattoon, Illinois	Site Public Contact - (Research@carle.com)
Carle at The Riverfront Danville, Illinois	Site Public Contact - (Research@Carle.com)
Cedars Sinai Medical Center Los Angeles, California
Chelsea Hospital Chelsea, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
City of Hope Comprehensive Cancer Center Duarte, California
City of Hope at Irvine Lennar Irvine, California
Coborn Cancer Center at Saint Cloud Hospital Saint Cloud, Minnesota	Site Public Contact - (coborncancercenter@centracare.com)
Community Hospital of Anaconda Anaconda, Montana	Site Public Contact - (mccinfo@mtcancer.org)
Community Medical Center Missoula, Montana	Site Public Contact - (mccinfo@mtcancer.org)
Corewell Health Beaumont Troy Hospital Troy, Michigan
Corewell Health Farmington Hills Hospital Farmington Hills, Michigan
Corewell Health William Beaumont University Hospital Royal Oak, Michigan
CoxHealth South Hospital Springfield, Missouri
Crossroads Cancer Center Effingham, Illinois	Site Public Contact - (morganthaler.jodi@mhsil.com)
Dartmouth Cancer Center - North Saint Johnsbury, Vermont	Site Public Contact - (cancer.research.nurse@hitchcock.org)
Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center Lebanon, New Hampshire	Site Public Contact - (cancer.research.nurse@dartmouth.edu)
Decatur Memorial Hospital Decatur, Illinois	Site Public Contact - (morganthaler.jodi@mhsil.com)
Duke University Medical Center Durham, North Carolina
Duluth Clinic Ashland Ashland, Wisconsin	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Emory Johns Creek Hospital Johns Creek, Georgia	Site Public Contact - (m.lisa.hwang@emory.edu)
Emory Saint Joseph's Hospital Atlanta, Georgia
Emory University Hospital Midtown Atlanta, Georgia
Emory University Hospital/Winship Cancer Institute Atlanta, Georgia
Essentia Health - Deer River Clinic Deer River, Minnesota	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Essentia Health Cancer Center Duluth, Minnesota	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Essentia Health Cancer Center-South University Clinic Fargo, North Dakota	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Essentia Health Hibbing Clinic Hibbing, Minnesota
Essentia Health Saint Joseph's Medical Center Brainerd, Minnesota	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Essentia Health Sandstone Sandstone, Minnesota	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Essentia Health Virginia Clinic Virginia, Minnesota	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Freeman Physician Group of Pittsburg Pittsburg, Kansas	Site Public Contact - (BNMathew@freemanhealth.com)
Froedtert and MCW Moorland Reserve Health Center New Berlin, Wisconsin
Genesee Hematology Oncology PC Flint, Michigan
Genesys Hurley Cancer Institute Flint, Michigan	Site Public Contact - (wstrong@ghci.org)
Grady Health System Atlanta, Georgia
Gundersen Lutheran Medical Center La Crosse, Wisconsin	Site Public Contact - (cancerctr@gundersenhealth.org)
HaysMed Hays, Kansas
Helen F Graham Cancer Center Newark, Delaware	Site Public Contact - (lbarone@christianacare.org)
Hematology Oncology Associates of CNY at Camillus Camillus, New York
Hematology Oncology Associates of Central New York-East Syracuse East Syracuse, New York
Hennepin County Medical Center Minneapolis, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Henry Ford Saint John Hospital - Macomb Medical Macomb, Michigan	Site Public Contact - (kforman1@hfhs.org)
Huntsman Cancer Institute/University of Utah Salt Lake City, Utah	Site Public Contact - (cancerinfo@hci.utah.edu)
Hurley Medical Center Flint, Michigan	Site Public Contact - (wstrong@ghci.org)
Huron Gastroenterology PC Ypsilanti, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
Illinois CancerCare - Washington Washington, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Bloomington Bloomington, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Canton Canton, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Carthage Carthage, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Dixon Dixon, Illinois
Illinois CancerCare-Eureka Eureka, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Galesburg Galesburg, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Kewanee Clinic Kewanee, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Macomb Macomb, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Ottawa Clinic Ottawa, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Pekin Pekin, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
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Illinois CancerCare-Peru Peru, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Princeton Princeton, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Iowa Methodist Medical Center Des Moines, Iowa
Kootenai Clinic Cancer Services - Post Falls Post Falls, Idaho	Site Public Contact - (mccinfo@mtcancer.org)
Kootenai Clinic Cancer Services - Sandpoint Sandpoint, Idaho	Site Public Contact - (mccinfo@mtcancer.org)
Kootenai Health - Coeur d'Alene Coeur d'Alene, Idaho	Site Public Contact - (mccinfo@mtcancer.org)
Laura and Isaac Perlmutter Cancer Center at NYU Langone New York, New York	Site Public Contact - (CancerTrials@nyulangone.org)
Lawrence Memorial Hospital Lawrence, Kansas	Site Public Contact - (Stephanie.Norris@LMH.ORG)
Logan Health Medical Center Kalispell, Montana	Site Public Contact - (mccinfo@mtcancer.org)
Marshfield Medical Center - Minocqua Minocqua, Wisconsin	Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org)
Marshfield Medical Center - Weston Weston, Wisconsin	Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org)
Marshfield Medical Center-EC Cancer Center Eau Claire, Wisconsin	Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org)
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Marshfield Medical Center-Rice Lake Rice Lake, Wisconsin	Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org)
Marshfield Medical Center-River Region at Stevens Point Stevens Point, Wisconsin	Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org)
Mary Greeley Medical Center Ames, Iowa
McFarland Clinic - Ames Ames, Iowa	Site Public Contact - (ksoder@mcfarlandclinic.com)
McFarland Clinic - Boone Boone, Iowa
McFarland Clinic - Jefferson Jefferson, Iowa
McFarland Clinic - Marshalltown Marshalltown, Iowa
McFarland Clinic - Trinity Cancer Center Fort Dodge, Iowa
McLaren Cancer Institute-Bay City Bay City, Michigan	Site Public Contact - (ctoadmin@karmanos.org)
McLaren Cancer Institute-Central Michigan Mount Pleasant, Michigan	Site Public Contact - (ctoadmin@karmanos.org)
McLaren Cancer Institute-Clarkston Clarkston, Michigan	Site Public Contact - (ctoadmin@karmanos.org)
McLaren Cancer Institute-Flint Flint, Michigan	Site Public Contact - (ctoadmin@karmanos.org)
McLaren Cancer Institute-Lapeer Region Lapeer, Michigan	Site Public Contact - (ctoadmin@karmanos.org)
McLaren Cancer Institute-Northern Michigan Petoskey, Michigan	Site Public Contact - (ctoadmin@karmanos.org)
Medical College of Wisconsin Milwaukee, Wisconsin
Medical Oncology Hematology Consultants PA Newark, Delaware	Site Public Contact - (lbarone@christianacare.org)
Medical University of South Carolina Charleston, South Carolina	Site Public Contact - (hcc-clinical-trials@musc.edu)
Memorial Hospital East Shiloh, Illinois	Site Public Contact - (dschwab@wustl.edu)
Mercy Hospital Coon Rapids, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Mercy Hospital South St Louis, Missouri	Site Public Contact - (Danielle.Werle@mercy.net)
Mercy Hospital Springfield Springfield, Missouri
Mercy Medical Center - Des Moines Des Moines, Iowa	Site Public Contact - (cancerresearch@mercydesmoines.org)
Minnesota Oncology Hematology PA-Woodbury Woodbury, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
MyMichigan Medical Center Saginaw Saginaw, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
MyMichigan Medical Center Tawas Tawas City, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
NYP/Weill Cornell Medical Center New York, New York
NYU Langone Hospital - Long Island Mineola, New York	Site Public Contact - (cancertrials@nyulangone.org)
Nebraska Medicine-Bellevue Bellevue, Nebraska	Site Public Contact - (unmcrsa@unmc.edu)
Nebraska Medicine-Village Pointe Omaha, Nebraska
Northwest Cancer Center - Hobart Hobart, Indiana
Northwest Cancer Center - Main Campus Crown Point, Indiana
Northwest Cancer Center - Valparaiso Valparaiso, Indiana	Site Public Contact - (CancerResearch@COMHS.org)
Northwest Oncology LLC Dyer, Indiana
Ohio State University Comprehensive Cancer Center Columbus, Ohio	Site Public Contact - (Jamesline@osumc.edu)
Oklahoma Cancer Specialists and Research Institute-Tulsa Tulsa, Oklahoma
Oncology Hematology Associates of Saginaw Valley PC Saginaw, Michigan
Park Nicollet Clinic - Saint Louis Park Saint Louis Park, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Prisma Health Cancer Institute - Butternut Greenville, South Carolina	Site Public Contact - (Kim.Williams3@prismahealth.org)
Prisma Health Cancer Institute - Easley Easley, South Carolina	Site Public Contact - (Kim.Williams3@prismahealth.org)
Prisma Health Cancer Institute - Eastside Greenville, South Carolina	Site Public Contact - (Kim.Williams3@prismahealth.org)
Prisma Health Cancer Institute - Faris Greenville, South Carolina	Site Public Contact - (Kim.Williams3@prismahealth.org)
Prisma Health Cancer Institute - Greer Greer, South Carolina	Site Public Contact - (Kim.Williams3@prismahealth.org)
Prisma Health Cancer Institute - Seneca Seneca, South Carolina	Site Public Contact - (Kim.Williams3@prismahealth.org)
Prisma Health Cancer Institute - Spartanburg Boiling Springs, South Carolina	Site Public Contact - (Kim.Williams3@prismahealth.org)
ProHealth D N Greenwald Center Mukwonago, Wisconsin	Site Public Contact - (research.institute@phci.org)
ProHealth Oconomowoc Memorial Hospital Oconomowoc, Wisconsin
Providence Newberg Medical Center Newberg, Oregon	Site Public Contact - (CanRsrchStudies@providence.org)
Providence Portland Medical Center Portland, Oregon	Site Public Contact - (CanRsrchStudies@providence.org)
Providence Saint Vincent Medical Center Portland, Oregon	Site Public Contact - (CanRsrchStudies@providence.org)
Providence Willamette Falls Medical Center Oregon City, Oregon	Site Public Contact - (CanRsrchStudies@providence.org)
Regions Hospital Saint Paul, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Rhode Island Hospital Providence, Rhode Island
Roswell Park Cancer Institute Buffalo, New York	Site Public Contact - (askroswell@roswellpark.org)
Saint Alphonsus Cancer Care Center-Boise Boise, Idaho	Site Public Contact - (stephanie.couch@stjoeshealth.org)
Saint Alphonsus Cancer Care Center-Caldwell Caldwell, Idaho	Site Public Contact - (stephanie.couch@stjoeshealth.org)
Saint Alphonsus Cancer Care Center-Nampa Nampa, Idaho	Site Public Contact - (mccinfo@mtcancer.org)
Saint Alphonsus Cancer Care Center-Ontario Ontario, Oregon	Site Public Contact - (mccinfo@mtcancer.org)
Saint Anthony Regional Hospital Carroll, Iowa	Site Public Contact - (sbenson@iora.org)
Saint Catherine Hospital Garden City, Kansas	Site Public Contact - (protocols@AllianceNCTN.org)
Saint Francis Medical Center Cape Girardeau, Missouri	Site Public Contact - (sfmc@sfmc.net)
Saint John's Hospital - Healtheast Maplewood, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Saint Luke's Cancer Institute - Boise Boise, Idaho	Site Public Contact - (eslinget@slhs.org)
Saint Luke's Cancer Institute - Fruitland Fruitland, Idaho	Site Public Contact - (eslinget@slhs.org)
Saint Luke's Cancer Institute - Meridian Meridian, Idaho	Site Public Contact - (eslinget@slhs.org)
Saint Luke's Cancer Institute - Nampa Nampa, Idaho	Site Public Contact - (eslinget@slhs.org)
Saint Luke's Hospital Chesterfield, Missouri
Saint Mary Medical Center Hobart, Indiana	Site Public Contact - (CancerResearch@COMHS.org)
Saint Mary's Oncology/Hematology Associates of West Branch West Branch, Michigan
Salina Regional Health Center Salina, Kansas	Site Public Contact - (mleepers@srhc.com)
Sanford Bismarck Medical Center Bismarck, North Dakota	Site Public Contact - (OncologyClinicalTrialsFargo@sanfordhealth.org)
Sanford Broadway Medical Center Fargo, North Dakota	Site Public Contact - (OncologyClinicalTrialsFargo@sanfordhealth.org)
Sanford Cancer Center Oncology Clinic Sioux Falls, South Dakota	Site Public Contact - (OncologyClinicTrialsSF@sanfordhealth.org)
Sanford Joe Lueken Cancer Center Bemidji, Minnesota	Site Public Contact - (OncologyClinicalTrialsFargo@sanfordhealth.org)
Sanford Roger Maris Cancer Center Fargo, North Dakota	Site Public Contact - (OncologyClinicalTrialsFargo@sanfordhealth.org)
Sanford USD Medical Center - Sioux Falls Sioux Falls, South Dakota	Site Public Contact - (OncologyClinicalTrialsSF@SanfordHealth.org)
Siteman Cancer Center at Christian Hospital St Louis, Missouri	Site Public Contact - (info@siteman.wustl.edu)
Siteman Cancer Center at Saint Peters Hospital City of Saint Peters, Missouri	Site Public Contact - (info@siteman.wustl.edu)
Siteman Cancer Center at West County Hospital Creve Coeur, Missouri	Site Public Contact - (info@siteman.wustl.edu)
Siteman Cancer Center-South County St Louis, Missouri	Site Public Contact - (info@siteman.wustl.edu)
Smilow Cancer Hospital Care Center - Guilford Guilford, Connecticut	Site Public Contact - (canceranswers@yale.edu)
Smilow Cancer Hospital Care Center - Waterford Waterford, Connecticut	Site Public Contact - (canceranswers@yale.edu)
Smilow Cancer Hospital Care Center - Westerly Westerly, Rhode Island	Site Public Contact - (canceranswers@yale.edu)
Smilow Cancer Hospital Care Center at Glastonbury Glastonbury, Connecticut	Site Public Contact - (canceranswers@yale.edu)
Smilow Cancer Hospital Care Center at Greenwich Greenwich, Connecticut	Site Public Contact - (canceranswers@yale.edu)
Smilow Cancer Hospital Care Center at Long Ridge Stamford, Connecticut	Site Public Contact - (canceranswers@yale.edu)
Smilow Cancer Hospital Care Center at Saint Francis Hartford, Connecticut	Site Public Contact - (canceranswers@yale.edu)
Smilow Cancer Hospital Care Center-Fairfield Fairfield, Connecticut	Site Public Contact - (canceranswers@yale.edu)
Smilow Cancer Hospital Care Center-Trumbull Trumbull, Connecticut	Site Public Contact - (canceranswers@yale.edu)
Smilow Cancer Hospital-Derby Care Center Derby, Connecticut	Site Public Contact - (canceranswers@yale.edu)
Smilow Cancer Hospital-Torrington Care Center Torrington, Connecticut	Site Public Contact - (canceranswers@yale.edu)
Smilow Cancer Hospital-Waterbury Care Center Waterbury, Connecticut	Site Public Contact - (canceranswers@yale.edu)
Southern Illinois University School of Medicine Springfield, Illinois
Springfield Clinic Springfield, Illinois
Springfield Memorial Hospital Springfield, Illinois	Site Public Contact - (pallante.beth@mhsil.com)
Swedish Cancer Institute-Edmonds Edmonds, Washington	Site Public Contact - (PCRC-NCORP@Swedish.org)
Swedish Cancer Institute-Issaquah Issaquah, Washington	Site Public Contact - (PCRC-NCORP@Swedish.org)
Swedish Medical Center-First Hill Seattle, Washington	Site Public Contact - (PCRC-NCORP@Swedish.org)
The Community Hospital Munster, Indiana
The University of Kansas Cancer Center - Olathe Olathe, Kansas	Site Public Contact - (OlatheCCResearch@kumc.edu)
Tower Cancer Research Foundation Beverly Hills, California	Site Public Contact - (towercancerresearch@toweroncology.com)
Trinity Health IHA Medical Group Hematology Oncology - Brighton Brighton, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
Trinity Health IHA Medical Group Hematology Oncology - Canton Canton, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital Chelsea, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus Ypsilanti, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
Trinity Health Medical Center - Brighton Brighton, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
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Trinity Health Saint Joseph Mercy Hospital Ann Arbor Ann Arbor, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
Trinity Health Saint Joseph Mercy Oakland Hospital Pontiac, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
Trinity Health Saint Mary Mercy Livonia Hospital Livonia, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
UI Health Care Mission Cancer and Blood - Ankeny Clinic Ankeny, Iowa
UI Health Care Mission Cancer and Blood - Des Moines Clinic Des Moines, Iowa
UI Health Care Mission Cancer and Blood - Laurel Clinic Des Moines, Iowa
UI Health Care Mission Cancer and Blood - Waukee Clinic Waukee, Iowa
UI Health Care Mission Cancer and Blood - West Des Moines Clinic Clive, Iowa
UI Healthcare Mission Cancer and Blood - Fort Dodge Fort Dodge, Iowa	Site Public Contact - (trials@missioncancer.com)
UNC Lineberger Comprehensive Cancer Center Chapel Hill, North Carolina	Site Public Contact - (cancerclinicaltrials@med.unc.edu)
UW Cancer Center at ProHealth Care Waukesha, Wisconsin	Site Public Contact - (Chanda.miller@phci.org)
United Hospital Saint Paul, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
University Health Truman Medical Center Kansas City, Missouri
University of Arkansas for Medical Sciences Little Rock, Arkansas
University of Illinois Chicago, Illinois
University of Iowa/Holden Comprehensive Cancer Center Iowa City, Iowa
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University of Nebraska Medical Center Omaha, Nebraska	Site Public Contact - (unmcrsa@unmc.edu)
University of Oklahoma Health Sciences Center Oklahoma City, Oklahoma	Site Public Contact - (ou-clinical-trials@ouhsc.edu)
University of Rochester Rochester, New York
University of Wisconsin Carbone Cancer Center - Eastpark Medical Center Madison, Wisconsin	Site Public Contact - (clinicaltrials@cancer.wisc.edu)
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Wayne State University/Karmanos Cancer Institute Detroit, Michigan	Site Public Contact - (ctoadmin@karmanos.org)
Weisberg Cancer Treatment Center Farmington Hills, Michigan	Site Public Contact - (ctoadmin@karmanos.org)
Wilmot Cancer Institute at Webster Webster, New York	Site Public Contact - (WCICTOresearch@urmc.rochester.edu)
Women's Diagnostic Center - Munster Munster, Indiana	Site Public Contact - (mnicholson@comhs.org)
Yale University New Haven, Connecticut	Site Public Contact - (canceranswers@yale.edu)
Yale-New Haven Hospital North Haven Medical Center North Haven, Connecticut	Site Public Contact - (canceranswers@yale.edu)

Health Education Approach to Lung Screening (HEALS)

Contact(s):

Massey IIT Research Operations - masseyepd@vcu.edu

Principal Investigator:

System ID: NCT06070870

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Interventions: BEHAVIORAL: Patient Navigation

Conditions: Lung Cancer

Keywords: Lung cancer, Screening

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Location	Contacts
Medical University of South Carolina Charleston, South Carolina	Ellen Gomez, MA - (gomezel@musc.edu)
University of North Carolina-Chapel Hill Carrboro, North Carolina	Christopher Lyu, MPA - (Christopher_Lyu@med.unc.edu)
Virginia Commonwealth University Richmond, Virginia	Massey CPC Team - (MasseyCPC@vcu.edu)

Oral Azacitidine in Transplant-Eligible Patients With Acute Myeloid Leukemia (AML) Suffering From Health-Inequality (REMAIN1)

Contact(s):

Massey IIT Research Operations - masseyepd@vcu.edu

Principal Investigator:

System ID: NCT06370000

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Inclusion Criteria:

* Patients must have histologically or cytologically confirmed non-Acute Promyelocytic (APL) FLT3 negative AML and have completed induction and consolidation as defined by the treating physician and must be in complete response (CR), Complete response with partial hematologic recovery (CRh), or Complete response with incomplete count recovery (CRi) at time of study enrollment * For patients in CR1, AML disease phenotype must be one that is considered for allo HCT in CR1 (intermediate or high risk by European Leukemia Net (ELN), MRD+ CR, slow clearance of MRD) or any AML phenotype (aside from FLT3+ and APL) in CR2 and beyond * Medically eligible for allogeneic hematopoietic cell transplant (allo HCT) as defined by either: treating physician discretion, transplant physician discretion, or hematopoietic cell transplantation-specific Comorbidity index (HCT-CI) index of 5 or less * Age ≥ 18 years * Enrollment must occur within 4 months of completion of therapy * A patient or staff identified health disparity in 1 of the 5 Centers for Disease Control (CDC) defined social determinants of health (SDOH). This may include financial difficulties, lack of caregiver support, difficulties with medical literacy, rurality, appropriate access to health care, lack of an appropriate allogeneic hematopoietic cell transplant (allo HCT) donor, substance abuse * Patient must have adequate organ function defined as: Creatinine clearance (by Cockroft-Gault formula) greater than or equal to 29 mL/min, total bilirubin and aspartate aminotransferase/ alanine transaminase (AST/ALT) ≤ to institutional 2x upper limit of normal (except Gilbert's syndrome, which may enroll if \< 2x patient's baseline total bilirubin) * Eastern Cooperative Oncology Group (ECOG) 0,1,2,3 * Ability to take oral medications * No history of malabsorption syndrome which, in the investigator's opinion, may inhibit absorption of oral medications * Women of childbearing potential must consent to effective contraception during study treatment and at least 6 months following the last dose. Women who are breastfeeding are also excluded * Male patients must consent to effective contraception during study and at least 3 months after last dose * Ability to understand and the willingness to sign a written informed consent document Exclusion Criteria A patient who meets any of the following exclusion criteria is ineligible to participate in the study. * FMS-like tyrosine kinase 3 (FLT3 ITD) or tyrosine kinase domain (TKD) mutation * Uncontrolled central nervous system (CNS) involvement * History of hypersensitivity or allergic reaction to azacitidine or its components * Stem cell transplant within previous 3 months prior to initiation of study therapy * Uncontrolled intercurrent illness or infection * History of prior therapy with oral azacitidine * Female patients who are pregnant or intend to donate eggs during the study or for 6 months after receiving their last dose of study drug * Male patients who intend to donate sperm during the course of this study or for 3 months after last dose * Other malignancy for which the patient is currently receiving therapy (except excisable skin cancer) * Medical, psychological, or social condition that, in the opinion of the investigator, may increase the participant's risk or limit the participant's adherence with study requirements

Interventions: DRUG: Oral Azacitidine

Conditions: Acute Myeloid Leukemia

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Location	Contacts
Virginia Commonwealth University Richmond, Virginia	Massey CTO Heme Team - (MasseyHemMlg@vcu.edu)

miroliverELAP® for the Treatment of Acute Liver Failure: A Phase 1 Trial

Contact(s):

Joshua Carlson - jcarlson@miromatrix.com

Principal Investigator:

System ID: NCT06285253

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Inclusion Criteria:

• 18 years to 80 years old at the time of signing the informed consent
• Subject must:
• be deemed competent to consent by an independent qualified practitioner, or
• have consent given by a Legally Authorized Representative
• Subject should be in the intensive care unit
• Be diagnosed with 4.1. Acute Liver Failure defined as:
• INR ≥ 2.0, and
• Hepatic Encephalopathy Grade II-III (West Haven Criteria), and
• Less than 4 weeks (28 days) of disease duration 4.2. Severe Acute Alcohol-Associated Hepatitis as defined as:
• Hepatic Encephalopathy Grade I-III (West Haven Criteria), and
• Model for End-Stage Liver Disease (MELD) Score ≥ 20, and
• INR ≥ 2.0, and
• No overt evidence of cirrhosis 4.3. Acute on Chronic Liver Failure:
• Hepatic Encephalopathy Grade I-III (West Haven Criteria), and
• Model for End-Stage Liver Disease (MELD) Score ≥ 20, and
• INR ≥ 2.0, 5\. Subject is not a candidate for liver transplant and will not become a candidate in the event of worsening conditions. Exclusion Criteria
• Grade IV West Haven Encephalopathy Criteria
• Previous liver transplant
• Currently requires chronic hemodialysis (CRRT or other forms of continuous renal replacement are allowed).
• Uncontrolled documented infection, hypotension, or refractory shock. This is defined as a need for a single vasopressor, or combination of vasopressors, that exceed a norepinephrine equivalent of 0.5 mcg/kg/min.
• Liver injury due to trauma
• Any current liver cancer
• Currently on medications with a narrow therapeutic index
• Platelet count \< 40,000 μL
• If the subject is intubated and has an acute lung injury
• Experiencing a bleeding event, defined as:
• Active gastrointestinal or other overt bleeding event, or
• Hemoglobin drop \> 3g/dL within the past 24 hours, or
• Received ≥ 3 units of red blood cell transfusion within the past 24 hours
• Female that is currently pregnant, planning to be pregnant, or currently breastfeeding
• Refusal to receive blood products

Interventions: COMBINATION_PRODUCT: miroliverELAP treatment

Conditions: Acute Liver Failure, Acute Liver Injury, Drug Induced, Acute on Chronic Liver Failure (ACLF), Acute Alcoholic Hepatitis

Keywords: Acute liver failure, Extracorporeal liver assist, Bioengineered liver

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Study Locations

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Location	Contacts
Cleveland Clinic Foundation Cleveland, Ohio
Intermountain Healthcare Murray, Utah
Mayo Clinic Jacksonville, Florida
Mount Sinai Recanati/Miller Transplantation Institute New York, New York
Northwestern Memorial Hospital Chicago, Illinois
University of Michigan Medical School Ann Arbor, Michigan
University of Minnesota Medical School Minneapolis, Minnesota
Virginia Commonwealth University Medical Center Richmond, Virginia

Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial (PREDICT)

Contact(s):

Rana McKay, MD - rmckay@health.ucsd.edu

Principal Investigator:

System ID: NCT06632977

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Inclusion Criteria:

* PRE-REGISTRATION: Histological or cytological evidence of prostate cancer. Patients with variant histologies including neuroendocrine, small cell and sarcomatoid prostate cancer are allowed to enroll and these will not be used as selection criteria for individual arms. Central pathology review is not required. * PRE-REGISTRATION: Measurable disease and/or non-measurable metastatic disease per RECIST version 1.1. * PRE-REGISTRATION: Tissue procured within 12 months of pre-registration (metastatic disease preferred over primary tissue, though both are acceptable) available for submission per Section 6.2. For patients who have progressed on A032102 and are pre-registering again, repeat tissue procurement will not be mandated. * PRE-REGISTRATION: Molecular report available performed as part of standard of care testing via any Clinical Laboratory Improvement Act (CLIA)-certified next generation sequencing (NGS) assay. Patients may be assigned based on pre-determined qualifying molecular/DNA alterations as stated in Section 4.8 after receipt of local molecular testing by the A032102 molecular tumor board (MTB). Final determination of arm assignment will be determined by the MTB. For qualifying DNA alteration determined by the MTB, testing may be from tumor tissue collected at any time or circulating tumor DNA (ctDNA) within 12 months of pre-registration. If no qualifying DNA alteration is identified based on the CLIA-certified next generation sequencing assay and MTB review, Caris testing, should be performed for both DNA/RNA profiling. Arm assignment based RNA requires testing of tumor tissue collected within 12 months of pre-registration and MTB review. * PRE-REGISTRATION: Age ≥ 18 years. * REGISTRATION: Progressive mCRPC as defined: 1) castrate levels of serum testosterone \< 50 ng/dL AND one or more of the following criteria (choose all the apply): * PSA progression, defined by at least 2 consecutive rising PSA values at a minimum of 1-week intervals with the most recent PSA value being 2.0 ng/mL or higher, if confirmed PSA rise is the only indication of progression. Patients who received an anti-androgen must have PSA progression after withdrawal of anti-androgen therapy. * Radiographic progression per RECIST 1.1 criteria for soft tissue lesions * Bone metastasis progression per Prostate Cancer Working Group 3 (PCWG3) criteria. * REGISTRATION: Patients selected to receive lutetium Lu 177 vipivotide tetraxetan treatment are required to have prostate-specific membrane antigen (PSMA) positive mCRPC as determined by investigator assessment. For reference, in the VISION trial this was defined as at least 1 PSMA+ metastatic lesion (defined as uptake greater than that of liver parenchyma in lesions of any size in any organ system) and no PSMA- lesions (defined as uptake equal to or lower than that of liver parenchyma in any lymph node with a short axis of at least 2.5 cm, in any solid organ lesion with a short axis of at least 1.0 cm, or in any bone lesion with a soft-tissue component of at least 1.0 cm in the short axis). * REGISTRATION: Prior treatment with androgen receptor signaling inhibitor (ARSI) in either the metastatic hormone sensitive setting or mCRPC is required. Prior taxane therapy in either metastatic hormone sensitive setting or mCRPC is mandated unless patient is taxane ineligible or the patient refuses taxane therapy. Prior lutetium LU177 vipivotide tetraxetan treatment is permitted but not mandated. Patients with known germline or somatic deleterious BRCA 1/2 mutations must have received a prior PARPi. * REGISTRATION: Resolved toxicities from previous anticancer therapy, defined as toxicities (other than alopecia) resolved to Common Terminology Criteria for Adverse Events (CTCAE) version 5.0, grade ≤ 1 or baseline. Note: Subjects may be enrolled with chronic, stable grade 2 toxicities (defined as no worsening to \> grade 2 for at least 3 months prior to registration and managed with standard of care treatment) that the investigator deems related to previous anticancer therapy, comprised of: * Chemotherapy-induced neuropathy * Fatigue * Residual toxicities from prior treatment: Grade 1 or grade 2 endocrinopathies which may include: Hypothyroidism/hyperthyroidism. type I diabetes, hyperglycemia, adrenal insufficiency, adrenalitis, skin hypopigmentation (vitiligo) * REGISTRATION: No cytotoxic, biologic, radiopharmaceutical or other non-kinase inhibitor investigational agent within 4 weeks of registration. Treatment with any type of small molecular kinase inhibitor (including investigational kinase inhibitor) within 2 weeks of registration. Treatment with abiraterone acetate, apalutamide, or darolutamide within 2 weeks of registration. Treatment with enzalutamide within 4 weeks of registration. No treatment with radiation therapy within 2 weeks of registration. * REGISTRATION: No major surgery within 4 weeks of registration. * REGISTRATION: No prior treatment with EZH inhibitors. * REGISTRATION: Prior treatment with cabazitaxel + carboplatin. * REGISTRATION: None of the following conditions: * Current use of moderate or strong cytochrome P450 (CYP)3A inducers. * Known or suspected hypersensitivity to valemetostat tosylate (DS-3201b) or any of the excipients. * For patients with evidence of chronic hepatitis B virus (HBV) infection, the HBV viral load must be undetectable on suppressive therapy, if indicated. Patients with a history of hepatitis C virus (HCV) infection must have been treated and cured. For patients with HCV infection who are currently on treatment, they are eligible if they have an undetectable HCV viral load. \* HIV-infected patients on effective anti-retroviral therapy with undetectable viral load within 6 months are eligible for this trial. * Imminent or established spinal cord compression based on clinical and/or imaging findings. * Known brain metastases or cranial epidural disease unless adequately treated with radiotherapy and/or surgery (including radiosurgery) and stable for at least 4 weeks prior to registration after radiotherapy or at least 4 weeks prior to registration after major surgery (e.g., removal or biopsy of brain metastasis). Patients must have complete wound healing from major surgery or minor surgery before registration. * Significant cardiovascular defined as: * Myocardial infarction within 6 months prior to enrollment. * Uncontrolled angina pectoris within 6 months prior to enrollment. * New York Heart Association Class 3 or 4 congestive heart failure. * Corrected QT interval calculated by the Fridericia\'s formula (QTcF) ≥ 470 ms per electrocardiogram (ECG) within 42 days before randomization in any individual with any history of any cardiac disease or medication which can impact QTcF. Patients with known history or current symptoms of cardiac disease, history of treatment with cardiotoxic agents, or agents/conditions known to impact QTcF should have a clinical risk assessment of cardiac function using the New York Heart Association Functional Classification and ECG. * Uncontrolled hypertension (resting systolic blood pressure \>160 mmHg or diastolic blood pressure \> 100 mmHg). * Clinically significant acute infection requiring systemic antibacterial, antifungal or antiviral therapy. * Moderate to severe hepatic impairment (Child-Pugh Class C) * REGISTRATION: No freezing or donating sperm ≤ 14 days prior to registration. * REGISTRATION: Eastern Cooperative Oncology Group (ECOG) performance status 0-2. * REGISTRATION: No granulocyte colony-stimulating factor (GCSF) within 2 weeks of registration. * REGISTRATION: No red blood cell (RBC) transfusions within 2 weeks of registration. * REGISTRATION: No platelet transfusions within 2 weeks of registration. * REGISTRATION: No bleeding diathesis. * REGISTRATION: White blood cell count (WBC) ≥ 2,500/mcL. * REGISTRATION: Absolute neutrophil count (ANC) ≥ 1,500/mcL. * REGISTRATION: Hemoglobin ≥ 9 g/dL. * REGISTRATION: Platelet count ≥ 100,000/mcL. * REGISTRATION: Creatinine clearance ≥ 30 mL/min as defined by Cockcroft-Gault equation. * REGISTRATION: Total bilirubin ≤ 1.5 x ULN (≤ 3 x upper limit of normal \[ULN\] for subjects with documented Gilbert\'s disease). * REGISTRATION: Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) ≤ 3 x ULN. * REGISTRATION: Albumin ≥ 2.8 g/dL. * REGISTRATION: The A032102 molecular tumor board will review the local pathology report and molecular sequencing report, and the Alliance registration/randomization office will relay the assignment to the submitting site. Once the site receives this assignment, they can register the patient to A032102. Any questions about the molecular board treatment assignments can be directed to A032102@alliancenctn.org. * RE-REGISTRATION: Progressive mCRPC (after receiving the tumor board assigned therapy) as defined: 1) castrate levels of serum testosterone \< 50 ng/dL AND 2) progressive disease defined by radiographic progression on conventional imaging (CT/MRI chest, abdomen and pelvis and bone scan within 42 days of re-registration). * RE-REGISTRATION: Resolved toxicities from previous anticancer therapy, defined as toxicities (other than alopecia) resolved to CTCAE version 5.0, grade ≤ 1 or baseline. Note: Subjects may be enrolled with chronic, stable grade 2 toxicities (defined as no worsening to \> grade 2 for at least 3 months prior to registration and managed with standard of care treatment) that the investigator deems related to previous anticancer therapy, comprised of: * Chemotherapy-induced neuropathy * Fatigue * Residual toxicities from prior treatment: Grade 1 or grade 2 endocrinopathies which may include: Hypothyroidism/hyperthyroidism. type I diabetes, hyperglycemia, adrenal insufficiency, adrenalitis, skin hypopigmentation (vitiligo). * RE-REGISTRATION: None of the following conditions: * Imminent or established spinal cord compression based on clinical and/or imaging findings. * Known brain metastases or cranial epidural disease unless adequately treated with radiotherapy and/or surgery (including radiosurgery) and stable for at least 4 weeks prior to registration after radiotherapy or at least 4 weeks prior to re-registration after major surgery (e.g., removal or biopsy of brain metastasis). Patients must have complete wound healing from major surgery or minor surgery before re-registration. * Corrected QT interval calculated by the Fridericia\'s formula (QTcF) \< 470 ms per ECG within 42 days before randomization in any individual with any history of any cardiac disease or medication which can impact QTcF. * Significant cardiovascular defined as: * Myocardial infarction within 6 months prior to enrollment. * Uncontrolled angina pectoris within 6 months prior to enrollment. * New York Heart Association Class 3 or 4 congestive heart failure. * Uncontrolled hypertension (resting systolic blood pressure \> 160 mmHg or diastolic blood pressure \> 100 mmHg). * RE-REGISTRATION: ECOG Performance Status 0-2. * RE-REGISTRATION: No GCSF within 2 weeks of registration. * RE-REGISTRATION: No RBC transfusions within 2 weeks of registration. * RE-REGISTRATION: No platelet transfusions within 2 weeks of registration. * RE-REGISTRATION: WBC ≥ 2,500/mcL. * RE-REGISTRATION: ANC ≥ 1,500/mcL. * RE-REGISTRATION: Hemoglobin ≥ 9 g/dL (transfusions permitted). * RE-REGISTRATION: Platelet count ≥ 100,000/mcL. * RE-REGISTRATION: Creatinine clearance ≥ 30 mL/min as defined by Cockcroft-Gault equation. * RE-REGISTRATION: Total bilirubin ≤ 1.5 x ULN (≤ 3 x ULN for subjects with documented Gilbert\'s disease). * RE-REGISTRATION: AST and ALT ≤ 3 x ULN. * RE-REGISTRATION: Albumin ≥ 2.8 g/dL. * RE-REGISTRATION: QT Interval (QTcF) \< 470 ms (in individuals with any cardiac history of any medication or condition known to impact QTcF). * RE-REGISTRATION: The A032102 molecular tumor board will review the CARIS molecular sequencing report, the Alliance registration/randomization office will relay the assignment to the site. Any questions about the molecular board treatment assignments can be directed to A032102@alliancenctn.org.

Exclusion Criteria:

Interventions: OTHER: Genetic testing, DRUG: Valemetostat Tosylate, PROCEDURE: Magnetic Resonance Imaging, PROCEDURE: Computed Tomography, PROCEDURE: Bone scan, PROCEDURE: FDG-Positron Emission Tomography, PROCEDURE: PSMA PET Scan, PROCEDURE: Biospecimen Collection, DRUG: Carboplatin, DRUG: Cabazitaxel, DRUG: Abiraterone Acetate, DRUG: Enzalutamide, DRUG: Lutetium Lu 177 Vipivotide Tetraxetan

Conditions: Castration-Resistant Prostate Carcinoma, Stage IVB Prostate Cancer AJCC v8

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Study Locations

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Location	Contacts
Banner University Medical Center - Tucson Tucson, Arizona	Site Public Contact - (UACC-IIT@uacc.arizona.edu)
Beebe Health Campus Rehoboth Beach, Delaware	Site Public Contact - (research@beebehealthcare.org)
Beebe South Coastal Health Campus Millville, Delaware	Site Public Contact - (research@beebehealthcare.org)
Billings Clinic Cancer Center Billings, Montana	Site Public Contact - (research@billingsclinic.org)
Bon Secours Cancer Institute at Reynolds Crossing Richmond, Virginia	Site Public Contact - (Anne_caramella@bshsi.org)
Bon Secours Memorial Regional Medical Center Mechanicsville, Virginia	Site Public Contact - (anne_carmellat@bshsi.org)
Bon Secours Richmond Community Hospital Richmond, Virginia	Site Public Contact - (anne_carmellat@bshsi.org)
Bon Secours Saint Francis Medical Center Midlothian, Virginia	Site Public Contact - (anne_carmellat@bshsi.org)
Bon Secours Saint Mary's Hospital Richmond, Virginia	Site Public Contact - (anne_carmellat@bshsi.org)
Cancer Care Center of O'Fallon O'Fallon, Illinois	Site Public Contact - (morganthaler.jodi@mhsil.com)
Cancer Care and Hematology-Fort Collins Fort Collins, Colorado	Site Public Contact - (protocols@AllianceNCTN.org)
Dana Farber-Merrimack Valley Methuen, Massachusetts
Dana-Farber Cancer Institute Boston, Massachusetts
Dana-Farber Cancer Institute at Foxborough Foxborough, Massachusetts
Dana-Farber/Brigham and Women's Cancer Center at Milford Regional Milford, Massachusetts
Dana-Farber/Brigham and Women's Cancer Center at South Shore South Weymouth, Massachusetts
Drexel Town Square Health Center Oak Creek, Wisconsin
Edwards Comprehensive Cancer Center Huntington, West Virginia	Site Public Contact - (Christina.Cole@chhi.org)
Froedtert Menomonee Falls Hospital Menomonee Falls, Wisconsin
Froedtert West Bend Hospital/Kraemer Cancer Center West Bend, Wisconsin
Guthrie Medical Group PC-Robert Packer Hospital Sayre, Pennsylvania
Hackensack University Medical Center Hackensack, New Jersey
Helen F Graham Cancer Center Newark, Delaware	Site Public Contact - (lbarone@christianacare.org)
Illinois CancerCare-Bloomington Bloomington, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Eureka Eureka, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Ottawa Clinic Ottawa, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Peru Peru, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Jupiter Medical Center Jupiter, Florida	Site Public Contact - (clinicaltrials@jupitermed.com)
Kootenai Health - Coeur d'Alene Coeur d'Alene, Idaho
MU Health - University Hospital/Ellis Fischel Cancer Center Columbia, Missouri
McFarland Clinic - Ames Ames, Iowa	Site Public Contact - (ksoder@mcfarlandclinic.com)
Medical Center of the Rockies Loveland, Colorado
Medical College of Wisconsin Milwaukee, Wisconsin
Medical Oncology Hematology Consultants PA Newark, Delaware	Site Public Contact - (lbarone@christianacare.org)
Memorial Hospital North Colorado Springs, Colorado
MetroHealth Medical Center Cleveland, Ohio	Site Public Contact - (ababal@metrohealth.org)
Mount Sinai Hospital New York, New York
Oregon Health and Science University Portland, Oregon	Site Public Contact - (trials@ohsu.edu)
Poudre Valley Hospital Fort Collins, Colorado
Providence Portland Medical Center Portland, Oregon	Site Public Contact - (CanRsrchStudies@providence.org)
Roswell Park Cancer Institute Buffalo, New York	Site Public Contact - (askroswell@roswellpark.org)
Saint Elizabeth Healthcare Edgewood Edgewood, Kentucky	Site Public Contact - (Kristi.Curtsinger@stelizabeth.com)
Saint Elizabeth Healthcare Fort Thomas Fort Thomas, Kentucky	Site Public Contact - (Kristi.Curtsinger@stelizabeth.com)
Swedish Cancer Institute-Edmonds Edmonds, Washington	Site Public Contact - (PCRC-NCORP@Swedish.org)
The University of Kansas Cancer Center - Olathe Olathe, Kansas	Site Public Contact - (OlatheCCResearch@kumc.edu)
Trinity Health IHA Medical Group Hematology Oncology - Brighton Brighton, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
Trinity Health IHA Medical Group Hematology Oncology - Canton Canton, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital Chelsea, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus Ypsilanti, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
Trinity Health Saint Mary Mercy Livonia Hospital Livonia, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
UC Irvine Health/Chao Family Comprehensive Cancer Center Orange, California	Site Public Contact - (ucstudy@uci.edu)
UC San Diego Health System - Encinitas Encinitas, California
UC San Diego Medical Center - Hillcrest San Diego, California	Site Public Contact - (rhabbaba@health.ucsd.edu)
UC San Diego Moores Cancer Center La Jolla, California	Site Public Contact - (cancercto@ucsd.edu)
UCHealth Greeley Hospital Greeley, Colorado	Site Public Contact - (protocols@AllianceNCTN.org)
UCHealth Memorial Hospital Central Colorado Springs, Colorado
UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care Irvine, California	Site Public Contact - (ucstudy@uci.edu)
UNC Lineberger Comprehensive Cancer Center Chapel Hill, North Carolina	Site Public Contact - (cancerclinicaltrials@med.unc.edu)
UT Southwestern Clinical Center at Richardson/Plano Richardson, Texas	Site Public Contact - (Suzanne.cole@utsouthwestern.edu)
UT Southwestern Simmons Cancer Center - RedBird Dallas, Texas	Site Public Contact - (canceranswerline@utsouthwestern.edu)
UT Southwestern/Simmons Cancer Center-Dallas Dallas, Texas	Site Public Contact - (canceranswerline@UTSouthwestern.edu)
UT Southwestern/Simmons Cancer Center-Fort Worth Fort Worth, Texas	Site Public Contact - (canceranswerline@UTSouthwestern.edu)
University of Arizona Cancer Center-North Campus Tucson, Arizona	Site Public Contact - (UACC-IIT@uacc.arizona.edu)
University of California Davis Comprehensive Cancer Center Sacramento, California
University of Iowa Healthcare Cancer Services Quad Cities Bettendorf, Iowa	Site Public Contact - (katherine-daprile@uiowa.edu)
University of Iowa/Holden Comprehensive Cancer Center Iowa City, Iowa
University of Kansas Cancer Center Kansas City, Kansas	Site Public Contact - (KUCC_Navigation@kumc.edu)
University of Kansas Health System Saint Francis Campus Topeka, Kansas
University of Kansas Hospital-Indian Creek Campus Overland Park, Kansas	Site Public Contact - (KUCC_Navigation@kumc.edu)
University of Kansas Hospital-Westwood Cancer Center Westwood, Kansas	Site Public Contact - (KUCC_Navigation@kumc.edu)
University of Michigan Health - Sparrow Lansing Lansing, Michigan	Site Public Contact - (harsha.trivedi@umhsparrow.org)
University of Oklahoma Health Sciences Center Oklahoma City, Oklahoma	Site Public Contact - (ou-clinical-trials@ouhsc.edu)
VCU Massey Cancer Center at Stony Point Richmond, Virginia	Site Public Contact - (ctoclinops@vcu.edu)
VCU Massey Comprehensive Cancer Center Richmond, Virginia	Site Public Contact - (CTOclinops@vcu.edu)
Vanderbilt University/Ingram Cancer Center Nashville, Tennessee
West Virginia University Charleston Division Charleston, West Virginia

Comparison of EVAR and ESAR for Infrarenal Aortic Aneurysms With a Wide Proximal Neck (HERCULES)

Contact(s):

Suzanne Holewijn, PhD - herculestrial@rijnstate.nl

Principal Investigator:

System ID: NCT05484115

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Interventions: DEVICE: endovascular aneurysm repair (EVAR) using the Endurant II/IIs stent graft system, DEVICE: endosuture aneurysm repair (ESAR) using Heli-FX EndoAnchor system

Conditions: Aortic Aneurysm, Abdominal

Keywords: AAA, Endovascular treatment, Wide proximal neck, EndoAnchors, Infrarenal, EVAR (Endovascular aneurysm repair), ESAR (Endosuture aneurysm repair), Endurant II/IIs stent graft system, Heli-FX EndoAnchor system

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Study Locations

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Location	Contacts
Alina Health Minneapolis, Minnesota
Ballad Health/Holston Valley Kingsport, Tennessee
Barnes-Jewish Hospital St Louis, Missouri
Beaumont University Hospital Royal Oak, Michigan
Catharina Ziekenhuis Eindhoven,
EHC-Hôpital de Morges Morges,
HCL Lyon Lyon,
Henry Ford Hospital Detroit, Michigan
Hospital Clinic de Barcelona Barcelona,
Hospital Clinico Universitario Lozano Blesa Zaragoza,
Hospital Ramon Y Cajal Madrid,
Hospital Universitario Miguel Servet Zaragoza,
IRCCS Ospedale Policlinico San Martino Genova, Metropolitan City of Genoa
Leeds General Infirmary Leeds,
Les Franciscaines Nîmes,
Loyola Maywood, Illinois
Mt Sinai Med Ctr Miami Beach, Florida
NC Heart& Vascular Raleigh, North Carolina
Noordwest ziekenhuis Alkmaar, North Holland
Osp. S.Orsola Malpighi - Bologna Bologna,
Promedica Toledo Hospital Toledo, Ohio
Queen Elizabeth University Hospital, Glasgow Glasgow,
Rijnstate hospital Arnhem,	Suzanne Holewijn, PhD - (herculestrial@rijnstate.nl) Daphne van der Veen, MSc - (herculestrial@rijnstate.nl)
Robert Wood Johnson University Medical Center New Brunswick, New Jersey
Saint Joseph Marseille Marseille,
Sisters of Charity hospital Buffalo, New York
Spaarne Gasthuis Haarlem, North Holland
St. George's Hospital London,
St. Mary's Hospital London,
Stony Brook University Medical Center Stony Brook, New York
University of Missouri Columbia, Missouri
Virginia Commonwealth University (VCU) Richmond, Virginia
Washington Regional Medical Center Washington, Arkansas

Selinexor With Combination With Induction/Consolidation Therapy in Acute Myeloid Leukemia Patients

Contact(s):

Study Coordinator - dfunes@wakehealth.edu

Principal Investigator:

System ID: NCT02835222

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Inclusion Criteria:

* Patients must have histologically or cytologically documented newly diagnosed de novo Acute Myeloid Leukemia (non-APL) that has not yet been treated. Hydrea,cytarabine and ATRA previous treatments are acceptable. * Patients with core binding factor acute myeloid leukemia (AML) (ie AML with t(8;21) or t(16;16) or i16) are not eligible. * Patients must not have a secondary AML (defined as a history of prior radiation therapy or systemic chemotherapy, CMML or MDS not treated with a hypomethylating agent) however history of previous MDS treated with a hypomethylating agent IS allowed. * Patients with de novo AML must not have partial or total monosomy 5 or 7 or i(17q) or t(17p). Negative FISH studies are sufficient for enrollment (i.e. FISH for -5, -7, +8, inv(16), t(8;21) and 17p). * Patients must not have mutated FLT3 (either ITD OR TKD mutations). * Hydroxyurea, leukapheresis or cytarabine may be used to control leukocytosis, provided that it is without Grade \>2 non-hematologic toxicity, and can be taken until start of therapy. * Age \>18 years. * ECOG performance status of ≤ 2 and fit for induction therapy in the opinion of the treating physician. * Laboratory values ≤2 weeks must be: * AST(SGOT)/ALT(SGPT)≤ 2.5 X institutional upper limit of normal * Bilirubin ≤ 2 X ULN (3X if known history of Gilbert'syndrome) * Creatinine clearance (CrCl) must be \> 20 mL/min * Baseline left ventricular ejection fraction of at least 40% by MUGA or ECHO. * Female patients of childbearing potential must agree to use 2 methods of contraception (including 1 highly effective and 1 effective method of contraception) and have a negative serum pregnancy test at Screening. Male patients must use an effective barrier method of contraception if sexually active with a female of childbearing potential. For both male and female patients, effective methods of contraception must be used throughout the study and for 3 months following the last dose of study treatment. * Ability to understand and the willingness to sign an IRB-approved informed consent document.

Exclusion Criteria:

* Patients who have received any therapy other than hydroxyurea, cytarabine or ATRA with the purpose of treating their AML or patients with core binding factor AML or Acute Promyelocytic Leukemia are not eligible. * Patients with a secondary AML (defined as a history of prior radiation therapy or systemic chemotherapy, CMML or MDS not treated with a hypomethylating agent) however history of previous MDS treated with a hypomethylating agent IS allowed. * Patients having received prior radiotherapy, treatment with cytotoxic agents, treatment with biologic agents or any anti-cancer therapy for a non-AML malignancy within the 4 weeks prior to treatment with selinexor, or those who have not fully recovered from the acute, non-hematological, non-infectious toxicities of any prior treatment with cytotoxic drugs, radiotherapy or other anti-cancer modalities (returned to baseline status as noted before most recent treatment). * Patients with another active malignancy that requires treatment excluding non-melanoma skin cancers. * Patients that have received a chemotherapy regimen with stem cell support in the previous 6 months. * Patients with known central nervous system involvement should be excluded from this clinical trial because the penetration of selinexor into the CNS is not currently known. * History of allergic reactions attributed to compounds of similar chemical or biologic composition to selinexor. * Uncontrolled concurrent illness including, but not limited to symptomatic congestive heart failure, unstable angina pectoris, or cardiac arrhythmia * Psychiatric illness/social situations that would limit compliance with study requirements. * Patients with known HIV infection or hepatitis (Note: Patients with known HIV infection are excluded because patients with an immune deficiency are at increased risk of lethal infections when treated with marrow-suppressive therapy. * Pregnant women are excluded from this study because of the potential for teratogenic or abortifacient effects. Because there is an unknown but potential risk for adverse events in nursing infants secondary to treatment of the mother, breastfeeding should be discontinued. * Patients unable to swallow tablets, patients with malabsorption syndrome, or any other GI disease or GI dysfunction that could interfere with absorption of study treatment * Prior exposure to a SINE compound

Interventions: DRUG: Cytarabine, DRUG: Daunorubicin Hydrochloride, DRUG: Selinexor

Conditions: Untreated Adult Acute Myeloid Leukemia

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Location	Contacts
Comprehensive Cancer Center of Wake Forest University Winston-Salem, North Carolina	Study Coordinator - (dfunes@wakehealth.edu)
Virginia Commonwealth University Massey Cancer Center Richmond, Virginia

Testing the Addition of an Anti-Cancer Drug, Irinotecan, to the Standard Chemotherapy Treatment (FOLFOX) After Long-Course Radiation Therapy for Advanced-Stage Rectal Cancers to Improve the Rate of Complete Response and Long-Term Rates of Organ Preservation (JANUS)

Contact(s):

J. Joshua Smith, MD - smithj5@mskcc.org

Principal Investigator:

System ID: NCT05610163

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Inclusion Criteria:

* Stage: Clinical stage II or III rectal adenocarcinoma defined as T4N0 or any T with node positive disease (any T, N+); also T3N0 requiring abdominal perineal resection (APR) or coloanal anastomosis * Tumor site: Rectum; =\< 12cm from the anal verge * No prior systemic chemotherapy, targeted therapy, or immunotherapy; or radiation therapy administered as treatment for colorectal cancer within the past 5 years is allowed * Not pregnant and not nursing, because this study involves an agent that has known genotoxic, mutagenic and teratogenic effects \* Therefore, for women of childbearing potential only, a negative pregnancy test (urine or serum according to institutional guidelines) done =\< 14 days prior to registration is required. Female subjects agree to use highly effective contraception combined with an additional barrier method (e.g, diaphragm, with a spermicide) while on study and for \>= 9 months after last dose of study drug, and the same criteria are applicable to male subjects if they have a partner of childbirth potential. Male subject agrees to use a condom and not donate sperm while in this study and for \>= 6 months after the last treatment * Age \>= 18 years * Eastern Cooperative Oncology Group (ECOG) performance status =\< 2 (or Karnofsky \>= 60%) * Absolute neutrophil count (ANC) \>= 1,500/mm\^3 * Platelet count \>= 100,000/mm * Creatinine =\< 1.5 x upper limit of normal (ULN) OR calculated (calc.) creatinine clearance \>= 50 mL/min \^3 * Total bilirubin =\< 1.5 x upper limit of normal (ULN) * Aspartate aminotransferase (AST)/alanine aminotransferase (ALT) =\< 3 x upper limit of normal (ULN) * No upper rectal tumors (distal margin of tumor \> 12 cm from the anal verge) * No recurrent rectal cancer; prior transanal excision, prior distal sigmoid cancer with a low anastomosis * No known mismatch repair deficient rectal adenocarcinoma * Human immunodeficiency virus HIV-infected patients on effective anti-retro viral therapy with undetectable viral load within 6 months are eligible for this trial * Patients with known history or current symptoms of cardiac disease, or history of treatment with cardio toxic agents, should have a clinical risk assessment of cardiac function using the New York Heart Association Functional Classification1. To be eligible for this trial, patients should be class 2B or better * Chronic concomitant treatment with strong inhibitors of CYP3A4 is not allowed on this study. Patients on strong CYP3A4 inhibitors must discontinue the drug for 14 days prior to registration on the study \* Chronic concomitant treatment with strong CYP3A4 inducers is not allowed. Patients must discontinue the drug 14 days prior to the start of study treatment

Interventions: DRUG: Capecitabine, DRUG: 5-fluorouracil, DRUG: Leucovorin calcium, DRUG: Irinotecan, DRUG: Oxaliplatin, RADIATION: Long Course Chemoradiotherapy, PROCEDURE: Computed Tomography, PROCEDURE: Magnetic Resonance Imaging, PROCEDURE: Sigmoidoscopy, PROCEDURE: biopsy

Conditions: Locally Advanced Rectal Carcinoma, Stage II Rectal Cancer AJCC v8, Stage III Rectal Cancer AJCC v8

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Location	Contacts
AMG Crystal Lake - Oncology Crystal Lake, Illinois	Site Public Contact - (advocateresearch@advocate.com)
AMG Libertyville - Oncology Libertyville, Illinois	Site Public Contact - (advocateresearch@advocatehealth.com)
Abbott-Northwestern Hospital Minneapolis, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
AdventHealth Altamonte Altamonte Springs, Florida
AdventHealth Celebration Celebration, Florida
AdventHealth East Orlando Orlando, Florida
AdventHealth Kissimmee Kissimmee, Florida
AdventHealth Littleton Littleton, Colorado
AdventHealth Orlando Orlando, Florida	Site Public Contact - (FH.Cancer.Research@flhosp.org)
AdventHealth Parker Parker, Colorado
AdventHealth Porter Denver, Colorado
Advocate Christ Medical Center Oak Lawn, Illinois
Advocate Good Samaritan Hospital Downers Grove, Illinois	Site Public Contact - (Barbara.barhamand@advocatehealth.com)
Advocate Good Shepherd Hospital Barrington, Illinois
Advocate High Tech Medical Park Palos Heights, Illinois	Site Public Contact - (ncorp@aah.org)
Advocate Illinois Masonic Medical Center Chicago, Illinois
Advocate Lutheran General Hospital Park Ridge, Illinois
Advocate Outpatient Center - Aurora Aurora, Illinois	Site Public Contact - (ncorp@aah.org)
Advocate Sherman Hospital Elgin, Illinois
Advocate South Suburban Hospital Hazel Crest, Illinois
Alaska Breast Care and Surgery LLC Anchorage, Alaska	Site Public Contact - (AKPAMC.OncologyResearchSupport@providence.org)
Alaska Oncology and Hematology LLC Anchorage, Alaska	Site Public Contact - (AKPAMC.OncologyResearchSupport@providence.org)
Alaska Women's Cancer Care Anchorage, Alaska	Site Public Contact - (AKPAMC.OncologyResearchSupport@providence.org)
Alegent Health Bergan Mercy Medical Center Omaha, Nebraska	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Alegent Health Immanuel Medical Center Omaha, Nebraska
Alegent Health Lakeside Hospital Omaha, Nebraska	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Allegheny General Hospital Pittsburgh, Pennsylvania
Allegiance Health Jackson, Michigan	Site Public Contact - (CTOResearch@hfhs.org)
Alliance for Childhood Diseases/Cure 4 the Kids Foundation Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
AnMed Health Cancer Center Anderson, South Carolina	Site Public Contact - (rhonda.ballew@anmedhealth.org)
Anchorage Associates in Radiation Medicine Anchorage, Alaska	Site Public Contact - (AKPAMC.OncologyResearchSupport@providence.org)
Anchorage Oncology Centre Anchorage, Alaska
Armes Family Cancer Center Findlay, Ohio	Site Public Contact - (clinical.trials@daytonncorp.org)
Arnold Palmer Cancer Center Medical Oncology Norwin N. Huntingdon, Pennsylvania	Site Public Contact - (haneydl@upmc.edu)
Aspirus Cancer Care - James Beck Cancer Center Rhinelander, Wisconsin	Site Public Contact - (Beth.Knetter@aspirus.org)
Aspirus Cancer Care - Stevens Point Stevens Point, Wisconsin	Site Public Contact - (Beth.Knetter@aspirus.org)
Aspirus Cancer Care - Wisconsin Rapids Wisconsin Rapids, Wisconsin
Aspirus Medford Hospital Medford, Wisconsin	Site Public Contact - (Beth.Knetter@aspirus.org)
Aspirus Regional Cancer Center Wausau, Wisconsin
Asplundh Cancer Pavilion Willow Grove, Pennsylvania	Site Public Contact - (ONCTrialNow@jefferson.edu)
Atrium Health Cabarrus/LCI-Concord Concord, North Carolina
Atrium Health Cleveland/LCI-Cleveland Shelby, North Carolina
Atrium Health Lincoln/LCI-Lincolnton Lincolnton, North Carolina
Atrium Health Pineville/LCI-Pineville Charlotte, North Carolina
Atrium Health Stanly/LCI-Albemarle Albemarle, North Carolina
Atrium Health Union/LCI-Union Monroe, North Carolina
Atrium Health University City/LCI-University Charlotte, North Carolina
Aultman Health Foundation Canton, Ohio	Site Public Contact - (ClinicalReserachDept@aultman.com)
Aurora Bay Area Medical Group-Marinette Marinette, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Aurora BayCare Medical Center Green Bay, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Aurora Cancer Care-Grafton Grafton, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Aurora Cancer Care-Kenosha South Kenosha, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Aurora Cancer Care-Milwaukee Milwaukee, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Aurora Cancer Care-Milwaukee West Wauwatosa, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Aurora Cancer Care-Racine Racine, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Aurora Cancer Care-Southern Lakes VLCC Burlington, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Aurora Health Care Germantown Health Center Germantown, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Aurora Medical Center in Summit Summit, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Aurora Saint Luke's Medical Center Milwaukee, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Aurora Sinai Medical Center Milwaukee, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Aurora West Allis Medical Center West Allis, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Avera Cancer Institute Sioux Falls, South Dakota	Site Public Contact - (OncRegulatory@avera.org)
Avera Cancer Institute - Mitchell Mitchell, South Dakota	Site Public Contact - (OncRegulatory@avera.org)
Avera Cancer Institute at Pierre Pierre, South Dakota	Site Public Contact - (OncRegulatory@avera.org)
Avera Cancer Institute at Yankton Yankton, South Dakota	Site Public Contact - (OncRegulatory@avera.org)
Avera Cancer Institute-Aberdeen Aberdeen, South Dakota	Site Public Contact - (oncregulatory@avera.org)
BJC Outpatient Center at Sunset Hills Sunset Hills, Missouri
Baptist Cancer Center-Grenada Grenada, Mississippi	Site Public Contact - (BCCclintrials@bmhcc.org)
Baptist Health Floyd New Albany, Indiana	Site Public Contact - (ctsucontact@westat.com)
Baptist Health Hamburg Lexington, Kentucky
Baptist Health Lexington Lexington, Kentucky
Baptist Health Louisville Louisville, Kentucky	Site Public Contact - (Cbcresearch@bhsi.com)
Baptist Health Paducah Paducah, Kentucky
Baptist Memorial Hospital and Cancer Center-Collierville Collierville, Tennessee	Site Public Contact - (BCCclintrials@bmhcc.org)
Baptist Memorial Hospital and Cancer Center-Desoto Southhaven, Mississippi	Site Public Contact - (BCCclintrials@bmhcc.org)
Baptist Memorial Hospital and Cancer Center-Golden Triangle Columbus, Mississippi	Site Public Contact - (BCCclintrials@bmhcc.org)
Baptist Memorial Hospital and Cancer Center-Memphis Memphis, Tennessee	Site Public Contact - (BCCclintrials@bmhcc.org)
Baptist Memorial Hospital and Cancer Center-Oxford Oxford, Mississippi	Site Public Contact - (BCCclintrials@bmhcc.org)
Baptist Memorial Hospital and Cancer Center-Union County New Albany, Mississippi	Site Public Contact - (BCCclintrials@bmhcc.org)
Bay Area Hospital Coos Bay, Oregon	Site Public Contact - (cherie.cox@bayareahospital.org)
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center Houston, Texas	Site Public Contact - (burton@bcm.edu)
Beebe Health Campus Rehoboth Beach, Delaware	Site Public Contact - (research@beebehealthcare.org)
Beebe Medical Center Lewes, Delaware	Site Public Contact - (research@beebehealthcare.org)
Beebe South Coastal Health Campus Millville, Delaware	Site Public Contact - (research@beebehealthcare.org)
Ben Taub General Hospital Houston, Texas
Benefis Sletten Cancer Institute Great Falls, Montana	Site Public Contact - (mccinfo@mtcancer.org)
Beth Israel Deaconess Medical Center Boston, Massachusetts
Bethesda North Hospital Cincinnati, Ohio	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Billings Clinic Cancer Center Billings, Montana	Site Public Contact - (research@billingsclinic.org)
Blanchard Valley Hospital Findlay, Ohio	Site Public Contact - (clinical.trials@daytonncorp.org)
Boston Medical Center Boston, Massachusetts
Bozeman Health Deaconess Hospital Bozeman, Montana	Site Public Contact - (mccinfo@mtcancer.org)
CHI Health Good Samaritan Kearney, Nebraska	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Camden Clark Medical Center Parkersburg, West Virginia	Site Public Contact - (cancertrialsinfo@hsc.wvu.edu)
Cancer Care Center of O'Fallon O'Fallon, Illinois	Site Public Contact - (morganthaler.jodi@mhsil.com)
Cancer Care Specialists of Illinois - Decatur Decatur, Illinois	Site Public Contact - (morganthaler.jodi@mhsil.com)
Cancer Center at Saint Joseph's Phoenix, Arizona	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Cancer Center of Western Wisconsin New Richmond, Wisconsin	Site Public Contact - (mmcorc@healthpartners.com)
Cancer Center-Metro Medical Center Bayamon Bayamón,
Carle BroMenn Medical Center Normal, Illinois	Site Public Contact - (Research@Carle.com)
Carle Cancer Center Urbana, Illinois	Site Public Contact - (Research@carle.com)
Carle Cancer Institute Normal Normal, Illinois	Site Public Contact - (Research@Carle.com)
Carle Physician Group-Effingham Effingham, Illinois	Site Public Contact - (Research@carle.com)
Carle Physician Group-Mattoon/Charleston Mattoon, Illinois	Site Public Contact - (Research@carle.com)
Carle at The Riverfront Danville, Illinois	Site Public Contact - (Research@Carle.com)
Carlisle Regional Cancer Center Carlisle, Pennsylvania	Site Public Contact - (protocols@AllianceNCTN.org)
Caro Cancer Center Caro, Michigan
Carolinas Medical Center/Levine Cancer Institute Charlotte, North Carolina
Castle Medical Center Kailua, Hawaii	Site Public Contact - (protocols@AllianceNCTN.org)
Central Care Cancer Center - Bolivar Bolivar, Missouri	Site Public Contact - (aroland@kccop.org)
Central Care Cancer Center - Garden City Garden City, Kansas	Site Public Contact - (aroland@kccop.org)
Central Care Cancer Center - Great Bend Great Bend, Kansas	Site Public Contact - (aroland@kccop.org)
Central Vermont Medical Center/National Life Cancer Treatment Berlin Corners, Vermont
Centralia Oncology Clinic Centralia, Illinois	Site Public Contact - (morganthaler.jodi@mhsil.com)
Centro Comprensivo de Cancer de UPR San Juan,	Site Public Contact - (ctsucontact@westat.com)
Chelsea Hospital Chelsea, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
Chester County Hospital West Chester, Pennsylvania
Chilton Medical Center Pompton, New Jersey
Christiana Care Health System-Christiana Hospital Newark, Delaware	Site Public Contact - (lbarone@christianacare.org)
Christiana Care Health System-Concord Health Center Chadds Ford, Pennsylvania	Site Public Contact - (lbarone@christianacare.org)
Christiana Care Health System-Wilmington Hospital Wilmington, Delaware	Site Public Contact - (lbarone@christianacare.org)
City of Hope Comprehensive Cancer Center Duarte, California
City of Hope South Bay Torrance, California
City of Hope South Pasadena South Pasadena, California
City of Hope Upland Upland, California
City of Hope at Irvine Lennar Irvine, California
Clackamas Radiation Oncology Center Clackamas, Oregon	Site Public Contact - (CanRsrchStudies@providence.org)
Community Medical Center Missoula, Montana	Site Public Contact - (mccinfo@mtcancer.org)
Comprehensive Cancer Centers of Nevada Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
Comprehensive Cancer Centers of Nevada - Central Valley Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
Comprehensive Cancer Centers of Nevada - Henderson Henderson, Nevada	Site Public Contact - (research@sncrf.org)
Comprehensive Cancer Centers of Nevada - Northwest Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
Comprehensive Cancer Centers of Nevada - Town Center Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
Comprehensive Cancer Centers of Nevada-Summerlin Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
Condell Memorial Hospital Libertyville, Illinois	Site Public Contact - (advocateresearch@advocatehealth.com)
Cooper Hospital University Medical Center Camden, New Jersey
Corewell Health Beaumont Troy Hospital Troy, Michigan
Corewell Health Dearborn Hospital Dearborn, Michigan
Corewell Health Farmington Hills Hospital Farmington Hills, Michigan
Corewell Health William Beaumont University Hospital Royal Oak, Michigan
CoxHealth South Hospital Springfield, Missouri
Creighton University Medical Center Omaha, Nebraska	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Crossroads Cancer Center Effingham, Illinois	Site Public Contact - (morganthaler.jodi@mhsil.com)
Dana Farber-Merrimack Valley Methuen, Massachusetts
Dana-Farber Cancer Institute Boston, Massachusetts
Dana-Farber Cancer Institute at Foxborough Foxborough, Massachusetts
Dana-Farber/Brigham and Women's Cancer Center at Milford Regional Milford, Massachusetts
Dana-Farber/Brigham and Women's Cancer Center at South Shore South Weymouth, Massachusetts
Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center Lebanon, New Hampshire	Site Public Contact - (cancer.research.nurse@dartmouth.edu)
Dayton Physician LLC - Englewood Dayton, Ohio	Site Public Contact - (clinical.trials@daytonncorp.org)
Dayton Physicians LLC - Troy Troy, Ohio	Site Public Contact - (clinical.trials@daytonncorp.org)
Dayton Physicians LLC-Atrium Franklin, Ohio	Site Public Contact - (clinical.trials@daytonncorp.org)
Dayton Physicians LLC-Miami Valley South Centerville, Ohio	Site Public Contact - (clinical.trials@daytonncorp.org)
Dayton Physicians LLC-Wayne Greenville, Ohio	Site Public Contact - (clinical.trials@daytonncorp.org)
Decatur Memorial Hospital Decatur, Illinois	Site Public Contact - (morganthaler.jodi@mhsil.com)
Delaware Clinical and Laboratory Physicians PA Newark, Delaware
Divine Providence Hospital Williamsport, Pennsylvania	Site Public Contact - (protocols@AllianceNCTN.org)
Doctors Cancer Center Manatí,
Drexel Town Square Health Center Oak Creek, Wisconsin
Duke Cancer Center Cary Cary, North Carolina	Site Public Contact - (NCTNStudyTeam@dm.duke.edu)
Duke Cancer Center Raleigh Raleigh, North Carolina	Site Public Contact - (NCTNStudyTeam@dm.duke.edu)
Duke University Medical Center Durham, North Carolina
Duluth Clinic Ashland Ashland, Wisconsin	Site Public Contact - (CancerTrials@EssentiaHealth.org)
East Carolina University Greenville, North Carolina	Site Public Contact - (eubankss@ecu.edu)
Edward Hospital/Cancer Center Naperville, Illinois
Edward Hospital/Cancer Center?Plainfield Plainfield, Illinois	Site Public Contact - (Cancerresearch@edward.org)
Elmhurst Memorial Hospital Elmhurst, Illinois	Site Public Contact - (Jrohde@emhc.org)
Emory Decatur Hospital Decatur, Georgia	Site Public Contact - (clinicaltrialsoncology@dekalbmedical.org)
Emory Johns Creek Hospital Johns Creek, Georgia	Site Public Contact - (m.lisa.hwang@emory.edu)
Emory Saint Joseph's Hospital Atlanta, Georgia
Emory University Hospital Midtown Atlanta, Georgia
Emory University Hospital/Winship Cancer Institute Atlanta, Georgia
Essentia Health - Deer River Clinic Deer River, Minnesota	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Essentia Health - Fosston Fosston, Minnesota	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Essentia Health - Jamestown Clinic Jamestown, North Dakota	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Essentia Health - Park Rapids Park Rapids, Minnesota	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Essentia Health Cancer Center Duluth, Minnesota	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Essentia Health Cancer Center-South University Clinic Fargo, North Dakota	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Essentia Health Hibbing Clinic Hibbing, Minnesota
Essentia Health Saint Joseph's Medical Center Brainerd, Minnesota	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Essentia Health Saint Mary's - Detroit Lakes Clinic Detroit Lakes, Minnesota	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Essentia Health Saint Mary's Hospital - Superior Superior, Wisconsin
Essentia Health Saint Mary's Medical Center Duluth, Minnesota	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Essentia Health Sandstone Sandstone, Minnesota	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Essentia Health Virginia Clinic Virginia, Minnesota	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Essentia Health-Hayward Clinic Hayward, Wisconsin	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Essentia Health-Spooner Clinic Spooner, Wisconsin	Site Public Contact - (CancerTrials@EssentiaHealth.org)
FHCC at EvergreenHealth Kirkland, Washington
Fairview Clinics and Surgery Center Maple Grove Maple Grove, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Fairview Southdale Hospital Edina, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Farmington Health Center Farmington, Utah	Site Public Contact - (cancerinfo@hci.utah.edu)
Forbes Hospital Monroeville, Pennsylvania
Fred Hutchinson Cancer Center Seattle, Washington
Freeman Health System Joplin, Missouri	Site Public Contact - (LJCrockett@freemanhealth.com)
Froedtert Menomonee Falls Hospital Menomonee Falls, Wisconsin
Froedtert West Bend Hospital/Kraemer Cancer Center West Bend, Wisconsin
Garnet Health Medical Center Middletown, New York	Site Public Contact - (jgerlach@garnethealth.org)
Gene Upshaw Memorial Tahoe Forest Cancer Center Truckee, California
GenesisCare USA - Fort Apache Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
GenesisCare USA - Las Vegas Las Vegas, Nevada
Genesys Hurley Cancer Institute Flint, Michigan	Site Public Contact - (wstrong@ghci.org)
George Washington University Medical Center Washington D.C., District of Columbia
Gibbs Cancer Center-Gaffney Gaffney, South Carolina	Site Public Contact - (kmertz-rivera@gibbscc.org)
Gibbs Cancer Center-Pelham Greer, South Carolina	Site Public Contact - (kmertz-rivera@gibbscc.org)
Glens Falls Hospital Glens Falls, New York
Good Samaritan Hospital - Cincinnati Cincinnati, Ohio	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Great Falls Clinic Great Falls, Montana	Site Public Contact - (mccinfo@mtcancer.org)
Greater Dayton Cancer Center Kettering, Ohio	Site Public Contact - (clinical.trials@daytonncorp.org)
Greater Regional Medical Center Creston, Iowa	Site Public Contact - (cancerresearch@mercydesmoines.org)
HSHS Saint Elizabeth's Hospital O'Fallon, Illinois	Site Public Contact - (morganthaler.jodi@mhsil.com)
Hartford Hospital Hartford, Connecticut
Hawaii Cancer Care - Westridge ‘Aiea, Hawaii	Site Public Contact - (info@hawaiicancercare.com)
Hawaii Cancer Care Inc - Waterfront Plaza Honolulu, Hawaii	Site Public Contact - (i.webster@hawaiicancercare.com)
Health Partners Inc Minneapolis, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Heartland Regional Medical Center Saint Joseph, Missouri	Site Public Contact - (Trisha.England2@mymlc.com)
Helen F Graham Cancer Center Newark, Delaware	Site Public Contact - (lbarone@christianacare.org)
Hennepin County Medical Center Minneapolis, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Henry Ford Cancer Institute-Downriver Brownstown, Michigan	Site Public Contact - (CTOResearch@hfhs.org)
Henry Ford Health Providence Novi Hospital Novi, Michigan	Site Public Contact - (kfife3@hfhs.org)
Henry Ford Health Providence Southfield Hospital Southfield, Michigan	Site Public Contact - (kfife3@hfhs.org)
Henry Ford Health Saint John Hospital Detroit, Michigan	Site Public Contact - (Kkeenan1@hfhs.org)
Henry Ford Health Warren Hospital Warren, Michigan	Site Public Contact - (kforman1@hfhs.org)
Henry Ford Hospital Detroit, Michigan	Site Public Contact - (CTOResearch@hfhs.org)
Henry Ford Macomb Hospital-Clinton Township Clinton Township, Michigan	Site Public Contact - (CTOResearch@hfhs.org)
Henry Ford Medical Center-Columbus Novi, Michigan	Site Public Contact - (CTOResearch@hfhs.org)
Henry Ford Saint John Hospital - Macomb Medical Macomb, Michigan	Site Public Contact - (kforman1@hfhs.org)
Henry Ford Saint John Hospital - Van Elslander Grosse Pointe Woods, Michigan	Site Public Contact - (kforman1@hfhs.org)
Henry Ford West Bloomfield Hospital West Bloomfield, Michigan	Site Public Contact - (CTOResearch@hfhs.org)
Hi-Line Sletten Cancer Center Havre, Montana	Site Public Contact - (protocols@AllianceNCTN.org)
Holy Cross Hospital Fort Lauderdale, Florida	Site Public Contact - (eileen.georgi@holy-cross.com)
Holy Name Hospital Teaneck, New Jersey
Huntsman Cancer Institute/University of Utah Salt Lake City, Utah	Site Public Contact - (cancerinfo@hci.utah.edu)
Hurley Medical Center Flint, Michigan	Site Public Contact - (wstrong@ghci.org)
IRMC Cancer Center Indiana, Pennsylvania	Site Public Contact - (haneydl@upmc.edu)
Idaho Urologic Institute-Meridian Meridian, Idaho
Illinois CancerCare - Washington Washington, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Bloomington Bloomington, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Canton Canton, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Carthage Carthage, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Dixon Dixon, Illinois
Illinois CancerCare-Eureka Eureka, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Galesburg Galesburg, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Kewanee Clinic Kewanee, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Macomb Macomb, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Ottawa Clinic Ottawa, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Pekin Pekin, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Peoria Peoria, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Peru Peru, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Princeton Princeton, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Indu and Raj Soin Medical Center Beavercreek, Ohio	Site Public Contact - (clinical.trials@daytonncorp.org)
Ingalls Memorial Hospital Harvey, Illinois	Site Public Contact - (clinicaltrials@ingalls.org)
Inova Fair Oaks Hospital Fairfax, Virginia	Site Public Contact - (Stephanie.VanBebber@inova.org)
Inova Fairfax Hospital Falls Church, Virginia	Site Public Contact - (Stephanie.VanBebber@inova.org)
Inova Loudoun Hospital Leesburg, Virginia	Site Public Contact - (Keary.janet@inova.org)
Inova Schar Cancer Institute Fairfax, Virginia	Site Public Contact - (Stephanie.VanBebber@inova.org)
Intermountain Health Lutheran Hospital Wheat Ridge, Colorado	Site Public Contact - (peaksresearch@imail.org)
Iowa Methodist Medical Center Des Moines, Iowa
Jefferson Cherry Hill Hospital Cherry Hill, New Jersey	Site Public Contact - (ONCTrialNow@jefferson.edu)
Jefferson Hospital Jefferson Hills, Pennsylvania	Site Public Contact - (ddefazio@wpahs.org)
Jefferson Torresdale Hospital Philadelphia, Pennsylvania	Site Public Contact - (ONCTrialNow@jefferson.edu)
John H Stroger Jr Hospital of Cook County Chicago, Illinois
John Muir Medical Center-Walnut Creek Walnut Creek, California	Site Public Contact - (clinicalresearch@johnmuirhealth.com)
Kadlec Clinic Hematology and Oncology Kennewick, Washington	Site Public Contact - (research@kadlecmed.org)
Kapiolani Medical Center for Women and Children Honolulu, Hawaii
Katmai Oncology Group Anchorage, Alaska	Site Public Contact - (AKPAMC.OncologyResearchSupport@providence.org)
Keck Medicine of USC Buena Park Buena Park, California
Kettering Medical Center Kettering, Ohio	Site Public Contact - (clinical.trials@daytonncorp.org)
Kingman Regional Medical Center Kingman, Arizona	Site Public Contact - (research@sncrf.org)
Kootenai Clinic Cancer Services - Post Falls Post Falls, Idaho	Site Public Contact - (mccinfo@mtcancer.org)
Kootenai Health - Coeur d'Alene Coeur d'Alene, Idaho	Site Public Contact - (mccinfo@mtcancer.org)
Kuakini Medical Center Honolulu, Hawaii
Lafayette Family Cancer Center-EMMC Brewer, Maine
Lahey Hospital and Medical Center Burlington, Massachusetts	Site Public Contact - (lhmc-cancer-clinical-trials@lahey.org)
Lahey Medical Center-Peabody Peabody, Massachusetts	Site Public Contact - (lhmc-cancer-clinical-trials@lahey.org)
Lake Regional Hospital Osage Beach, Missouri	Site Public Contact - (clinicaltrials@lakeregional.com)
Lakeview Hospital Stillwater, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Langlade Hospital and Cancer Center Antigo, Wisconsin	Site Public Contact - (Juli.Alford@aspirus.org)
Laura and Isaac Perlmutter Cancer Center at NYU Langone New York, New York	Site Public Contact - (CancerTrials@nyulangone.org)
Legacy Cancer Institute Medical Oncology and Day Treatment Vancouver, Washington	Site Public Contact - (oncologyresearch@lhs.org)
Legacy Good Samaritan Hospital and Medical Center Portland, Oregon	Site Public Contact - (cancer@lhs.org)
Legacy Meridian Park Hospital Tualatin, Oregon
Legacy Mount Hood Medical Center Gresham, Oregon
Legacy Salmon Creek Hospital Vancouver, Washington
Lehigh Valley Hospital - Muhlenberg Bethlehem, Pennsylvania	Site Public Contact - (Morgan_M.Horton@lvhn.org)
Lehigh Valley Hospital-Cedar Crest Allentown, Pennsylvania	Site Public Contact - (Morgan_M.Horton@lvhn.org)
Lenox Hill Hospital New York, New York
Levine Cancer Institute - Rutherford Forest City, North Carolina
Levine Cancer Institute - Union West Matthews, North Carolina
Levine Cancer Institute-Ballantyne Charlotte, North Carolina
Levine Cancer Institute-Gaston Gastonia, North Carolina
Levine Cancer Institute-Rock Hill Rock Hill, South Carolina
Levine Cancer Institute-SouthPark Charlotte, North Carolina
Lexington Medical Center West Columbia, South Carolina
Logan Health Medical Center Kalispell, Montana	Site Public Contact - (mccinfo@mtcancer.org)
Long Island Jewish Medical Center New Hyde Park, New York
Longmont United Hospital Longmont, Colorado	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Los Angeles General Medical Center Los Angeles, California	Site Public Contact - (uscnorrisinfo@med.usc.edu)
Lutheran Hospital - Cancer Centers of Colorado Golden, Colorado	Site Public Contact - (peaksresearch@imail.org)
Lyndon Baines Johnson General Hospital Houston, Texas
M D Anderson Cancer Center Houston, Texas	Site Public Contact - (askmdanderson@mdanderson.org)
MD Anderson League City League City, Texas	Site Public Contact - (askmdanderson@mdanderson.org)
MD Anderson West Houston Houston, Texas	Site Public Contact - (askmdanderson@mdanderson.org)
MD Anderson in Sugar Land Sugar Land, Texas	Site Public Contact - (askmdanderson@mdanderson.org)
MD Anderson in The Woodlands Conroe, Texas	Site Public Contact - (askmdanderson@mdanderson.org)
MU Health Care Goldschmidt Cancer Center Jefferson City, Missouri
MUSC Health Tidelands Health Radiation Therapy Center Murrells Inlet, South Carolina
Manhattan Eye Ear and Throat Hospital New York, New York
Marshfield Medical Center - Minocqua Minocqua, Wisconsin	Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org)
Marshfield Medical Center - Weston Weston, Wisconsin	Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org)
Marshfield Medical Center-EC Cancer Center Eau Claire, Wisconsin	Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org)
Marshfield Medical Center-Marshfield Marshfield, Wisconsin	Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org)
Marshfield Medical Center-Rice Lake Rice Lake, Wisconsin	Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org)
Marshfield Medical Center-River Region at Stevens Point Stevens Point, Wisconsin	Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org)
Mayo Clinic Hospital in Arizona Phoenix, Arizona
Mayo Clinic in Florida Jacksonville, Florida
Mayo Clinic in Rochester Rochester, Minnesota
MedStar Franklin Square Medical Center/Weinberg Cancer Institute Baltimore, Maryland
MedStar Georgetown University Hospital Washington D.C., District of Columbia
MedStar Good Samaritan Hospital Baltimore, Maryland
Medical College of Wisconsin Milwaukee, Wisconsin
Medical Oncology Hematology Consultants PA Newark, Delaware	Site Public Contact - (lbarone@christianacare.org)
Medical University of South Carolina Charleston, South Carolina	Site Public Contact - (hcc-clinical-trials@musc.edu)
Medstar Washington Hospital Center Washington D.C., District of Columbia
Memorial Health University Medical Center Savannah, Georgia	Site Public Contact - (Lorraine.OHara@hcahealthcare.com)
Memorial Hospital North Colorado Springs, Colorado
Memorial Hospital West Pembroke Pines, Florida
Memorial Hospital of Carbondale Carbondale, Illinois	Site Public Contact - (clinical.research@sih.net)
Memorial Regional Hospital/Joe DiMaggio Children's Hospital Hollywood, Florida	Site Public Contact - (OHR@mhs.net)
Memorial Sloan Kettering Basking Ridge Basking Ridge, New Jersey
Memorial Sloan Kettering Bergen Montvale, New Jersey
Memorial Sloan Kettering Cancer Center New York, New York
Memorial Sloan Kettering Commack Commack, New York
Memorial Sloan Kettering Monmouth Middletown, New Jersey
Memorial Sloan Kettering Nassau Uniondale, New York
Memorial Sloan Kettering Westchester Harrison, New York
Mercy Cancer Center Merced, California
Mercy Cancer Center - Cape Girardeau Cape Girardeau, Missouri
Mercy Cancer Center - Carmichael Carmichael, California	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Mercy Cancer Center - Elk Grove Elk Grove, California	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Mercy Cancer Center - Rocklin Rocklin, California	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Mercy Cancer Center - Sacramento Sacramento, California	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Mercy Cancer Center-West Lakes Clive, Iowa	Site Public Contact - (cancerresearch@mercydesmoines.org)
Mercy Clinic-Rolla-Cancer and Hematology Rolla, Missouri
Mercy Hospital Coon Rapids, Minnesota
Mercy Hospital Coon Rapids, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Mercy Hospital Fort Smith Fort Smith, Arkansas
Mercy Hospital Joplin Joplin, Missouri	Site Public Contact - (esmeralda.carrillo@mercy.net)
Mercy Hospital Oklahoma City Oklahoma City, Oklahoma
Mercy Hospital Saint Louis St Louis, Missouri
Mercy Hospital South St Louis, Missouri	Site Public Contact - (Danielle.Werle@mercy.net)
Mercy Hospital Springfield Springfield, Missouri
Mercy Medical Center - Des Moines Des Moines, Iowa	Site Public Contact - (cancerresearch@mercydesmoines.org)
Mercy Medical Center-West Lakes West Des Moines, Iowa	Site Public Contact - (cancerresearch@mercydesmoines.org)
Mercy San Juan Medical Center Carmichael, California	Site Public Contact - (OncologyResearch@DignityHealth.org)
Methodist Medical Center of Illinois Peoria, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
MetroHealth Medical Center Cleveland, Ohio	Site Public Contact - (ababal@metrohealth.org)
Michigan Healthcare Professionals Pontiac Pontiac, Michigan	Site Public Contact - (Emily.Crofts@trinity-health.org)
Midstate Medical Center Meriden, Connecticut
Miller-Dwan Hospital Duluth, Minnesota	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Minnesota Oncology - Burnsville Burnsville, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Minnesota Oncology Hematology PA-Maplewood Maplewood, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Minnesota Oncology Hematology PA-Woodbury Woodbury, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Mission Hope Medical Oncology - Arroyo Grande Arroyo Grande, California	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Mission Hope Medical Oncology - Santa Maria Santa Maria, California	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Missouri Baptist Medical Center St Louis, Missouri
Missouri Baptist Sullivan Hospital Sullivan, Missouri
Montefiore Medical Center - Moses Campus The Bronx, New York	Site Public Contact - (eskwak@montefiore.org)
Montefiore Medical Center-Einstein Campus The Bronx, New York	Site Public Contact - (eskwak@montefiore.org)
Montefiore Medical Center-Weiler Hospital The Bronx, New York	Site Public Contact - (eskwak@montefiore.org)
Monticello Cancer Center Monticello, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Morristown Medical Center Morristown, New Jersey
Morton Plant Hospital Clearwater, Florida
Mount Sinai Comprehensive Cancer Center at Aventura Aventura, Florida	Site Public Contact - (yenrique@msmc.com)
Mount Sinai Hospital New York, New York	Site Public Contact - (CCTO@mssm.edu)
Mount Sinai Medical Center Miami Beach, Florida	Site Public Contact - (yenrique@msmc.com)
Mount Sinai West New York, New York	Site Public Contact - (CCTO@mssm.edu)
MyMichigan Medical Center Midland Midland, Michigan	Site Public Contact - (CVResearch@mymichigan.org)
MyMichigan Medical Center Saginaw Saginaw, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
MyMichigan Medical Center Tawas Tawas City, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center New York, New York	Site Public Contact - (cancerclinicaltrials@cumc.columbia.edu)
NYP/Weill Cornell Medical Center New York, New York
NYU Langone Hospital - Brooklyn Brooklyn, New York	Site Public Contact - (david.wallach@nyulangone.org)
NYU Langone Hospital - Long Island Mineola, New York	Site Public Contact - (cancertrials@nyulangone.org)
New Hampshire Oncology Hematology PA-Concord Concord, New Hampshire
New York-Presbyterian/Brooklyn Methodist Hospital Brooklyn, New York
North Memorial Medical Health Center Robbinsdale, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
North Shore University Hospital Manhasset, New York
North Star Lodge Cancer Center at Yakima Valley Memorial Hospital Yakima, Washington	Site Public Contact - (Memorial-ClinicalTrials@yvmh.org)
Northern Westchester Hospital Mount Kisco, New York	Site Public Contact - (AMellor@northwell.edu)
Northwell Health Cancer Institute at Huntington Greenlawn, New York
Northwell Health Physicians Partners Radiation Medicine at Queens Forest Hills, New York
Northwell Health/Center for Advanced Medicine Lake Success, New York
Northwest Cancer Center - Hobart Hobart, Indiana
Northwest Cancer Center - Main Campus Crown Point, Indiana
Northwest Cancer Center - Valparaiso Valparaiso, Indiana	Site Public Contact - (CancerResearch@COMHS.org)
Northwest Oncology LLC Dyer, Indiana
Northwest Wisconsin Cancer Center Ashland, Wisconsin	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Northwestern Medicine Cancer Center Delnor Geneva, Illinois	Site Public Contact - (Donald.Smith3@nm.org)
Northwestern Medicine Cancer Center Kishwaukee DeKalb, Illinois	Site Public Contact - (Donald.Smith3@nm.org)
Northwestern Medicine Cancer Center Warrenville Warrenville, Illinois	Site Public Contact - (Donald.Smith3@nm.org)
Northwestern Medicine Glenview Outpatient Center Glenview, Illinois
Northwestern Medicine Grayslake Outpatient Center Grayslake, Illinois
Northwestern Medicine Lake Forest Hospital Lake Forest, Illinois	Site Public Contact - (cancertrials@northwestern.edu)
Northwestern University Chicago, Illinois	Site Public Contact - (cancer@northwestern.edu)
OSF Saint Anthony's Health Center Alton, Illinois
OSF Saint Joseph Medical Center Bloomington, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Ochsner Hematology Oncology North Shore - Covington (West Region) Covington, Louisiana	Site Public Contact - (Cheryl.kesler@ochsner.org)
Ochsner Medical Center Jefferson New Orleans, Louisiana	Site Public Contact - (Elisemarie.curry@ochsner.org)
Ohio State University Comprehensive Cancer Center Columbus, Ohio	Site Public Contact - (Jamesline@osumc.edu)
Oncology Associates at Mercy Medical Center Cedar Rapids, Iowa
Oncology Hematology Associates of Saginaw Valley PC Saginaw, Michigan
Oncology Hematology Care Inc-Kenwood Cincinnati, Ohio
OptumCare Cancer Care at Charleston Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
OptumCare Cancer Care at Fort Apache Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
OptumCare Cancer Care at MountainView Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
OptumCare Cancer Care at Seven Hills Henderson, Nevada	Site Public Contact - (research@sncrf.org)
Orion Cancer Care Findlay, Ohio	Site Public Contact - (clinical.trials@daytonncorp.org)
Overlook Hospital Summit, New Jersey
PCR Oncology Arroyo Grande, California	Site Public Contact - (research@sncrf.org)
Pacific Central Coast Health Center-San Luis Obispo San Luis Obispo, California	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Pali Momi Medical Center ‘Aiea, Hawaii
Pan American Center for Oncology Trials LLC San Juan,	Site Public Contact - (marcia.cruzcorrea@panoncologytrials.com)
Park Nicollet Clinic - Saint Louis Park Saint Louis Park, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Parkland Health Center - Farmington Farmington, Missouri
Parkland Memorial Hospital Dallas, Texas	Site Public Contact - (canceranswerline@UTSouthwestern.edu)
Parkview Regional Medical Center Fort Wayne, Indiana
PeaceHealth Saint John Medical Center Longview, Washington	Site Public Contact - (kmakin-bond@peacehealth.org)
PeaceHealth Saint Joseph Medical Center Bellingham, Washington
PeaceHealth Southwest Medical Center Vancouver, Washington	Site Public Contact - (kmakin-bond@peacehealth.org)
PeaceHealth United General Medical Center Sedro-Woolley, Washington	Site Public Contact - (rcrompton@peacehealth.org)
Penn State Milton S Hershey Medical Center Hershey, Pennsylvania	Site Public Contact - (CTO@hmc.psu.edu)
Penrose-Saint Francis Healthcare Colorado Springs, Colorado	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Phelps Health Delbert Day Cancer Institute Rolla, Missouri	Site Public Contact - (research@phelpshealth.org)
Phelps Memorial Hospital Center Sleepy Hollow, New York
Pocono Medical Center East Stroudsburg, Pennsylvania	Site Public Contact - (Morgan_M.Horton@lvhn.org)
Prisma Health Cancer Institute - Eastside Greenville, South Carolina
Prisma Health Cancer Institute - Faris Greenville, South Carolina
Prisma Health Cancer Institute - Greer Greer, South Carolina
Prisma Health Cancer Institute - Seneca Seneca, South Carolina
ProHealth D N Greenwald Center Mukwonago, Wisconsin	Site Public Contact - (research.institute@phci.org)
ProHealth Oconomowoc Memorial Hospital Oconomowoc, Wisconsin
Providence Alaska Medical Center Anchorage, Alaska	Site Public Contact - (AKPAMC.OncologyResearchSupport@providence.org)
Providence Cancer Institute Clackamas Clinic Clackamas, Oregon
Providence Medical Foundation - Santa Rosa Santa Rosa, California
Providence Newberg Medical Center Newberg, Oregon	Site Public Contact - (CanRsrchStudies@providence.org)
Providence Portland Medical Center Portland, Oregon	Site Public Contact - (CanRsrchStudies@providence.org)
Providence Queen of The Valley Napa, California
Providence Regional Cancer Partnership Everett, Washington	Site Public Contact - (marilyn.birchman@providence.org)
Providence Regional Cancer System-Aberdeen Aberdeen, Washington	Site Public Contact - (deidre.dillon@providence.org)
Providence Regional Cancer System-Centralia Centralia, Washington	Site Public Contact - (deidre.dillon@providence.org)
Providence Regional Cancer System-Lacey Lacey, Washington	Site Public Contact - (deidre.dillon@providence.org)
Providence Saint Joseph Medical Center/Disney Family Cancer Center Burbank, California	Site Public Contact - (Najee.Boucher@providence.org)
Providence Saint Mary Regional Cancer Center Walla Walla, Washington	Site Public Contact - (Cheryl.Dodd@providence.org)
Providence Saint Vincent Medical Center Portland, Oregon	Site Public Contact - (CanRsrchStudies@providence.org)
Providence Willamette Falls Medical Center Oregon City, Oregon	Site Public Contact - (CanRsrchStudies@providence.org)
Queen's Cancer Cenrer - POB I Honolulu, Hawaii
Queen's Cancer Center - Kuakini Honolulu, Hawaii
Queen's Cancer Center - Pearlridge ‘Aiea, Hawaii
Queen's Medical Center Honolulu, Hawaii
Queens Cancer Center Rego Park, New York
Radiation Oncology Associates Reno, Nevada	Site Public Contact - (research@sncrf.org)
Radiation Oncology Centers of Nevada Central Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
Radiation Oncology Centers of Nevada Southeast Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
Reading Hospital West Reading, Pennsylvania
Regions Hospital Saint Paul, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Reid Health Richmond, Indiana	Site Public Contact - (clinical.trials@daytonncorp.org)
Renown Regional Medical Center Reno, Nevada	Site Public Contact - (research@sncrf.org)
Rice Memorial Hospital Willmar, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Ridgeview Medical Center Waconia, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Rock Hill Radiation Therapy Center Rock Hill, South Carolina
Rocky Mountain Cancer Centers-Penrose Colorado Springs, Colorado	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Roswell Park Cancer Institute Buffalo, New York	Site Public Contact - (askroswell@roswellpark.org)
Rush - Copley Medical Center Aurora, Illinois	Site Public Contact - (Cancer.Research@rushcopley.com)
SIH Cancer Institute Carterville, Illinois	Site Public Contact - (clinical.research@sih.net)
SMC Center for Hematology Oncology Union Union, South Carolina	Site Public Contact - (kmertz-rivera@gibbscc.org)
SSM Health Good Samaritan Mount Vernon, Illinois	Site Public Contact - (gayla.hall@ssmhealth.com)
SUNY Upstate Medical Center-Community Campus Syracuse, New York
Saint Alphonsus Cancer Care Center-Boise Boise, Idaho
Saint Alphonsus Cancer Care Center-Caldwell Caldwell, Idaho
Saint Alphonsus Cancer Care Center-Nampa Nampa, Idaho
Saint Anthony Hospital Lakewood, Colorado	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Saint Anthony North Hospital Westminster, Colorado	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Saint Anthony's Hospital Cancer Care Center St. Petersburg, Florida	Site Public Contact - (Research.CTO@baycare.org)
Saint Charles Health System Bend, Oregon	Site Public Contact - (nosall@stcharleshealthcare.org)
Saint Elizabeth Boardman Hospital Boardman, Ohio
Saint Elizabeth Healthcare Edgewood Edgewood, Kentucky	Site Public Contact - (barbara.logan@stelizabeth.com)
Saint Elizabeth Healthcare Fort Thomas Fort Thomas, Kentucky	Site Public Contact - (barbara.logan@stelizabeth.com)
Saint Elizabeth Youngstown Hospital Youngstown, Ohio	Site Public Contact - (clinical.trials@daytonncorp.org)
Saint Francis Cancer Center Greenville, South Carolina	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Saint Francis Medical Center Cape Girardeau, Missouri	Site Public Contact - (sfmc@sfmc.net)
Saint Francis Regional Medical Center Shakopee, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Saint Helena Hospital St. Helena, California
Saint James Community Hospital and Cancer Treatment Center Butte, Montana
Saint John's Hospital - Healtheast Maplewood, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Saint Joseph Hospital Lexington, Kentucky	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Saint Joseph Hospital - Cancer Centers of Colorado Denver, Colorado	Site Public Contact - (peaksresearch@imail.org)
Saint Joseph Hospital - Orange Orange, California
Saint Joseph Hospital East Lexington, Kentucky	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Saint Joseph Radiation Oncology Resource Center Lexington, Kentucky	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Saint Joseph Warren Hospital Warren, Ohio
Saint Joseph's Hospital-North Lutz, Florida	Site Public Contact - (Research.cto@baycare.org)
Saint Joseph's Hospital/Children's Hospital-Tampa Tampa, Florida	Site Public Contact - (jennifer.manns@baycare.org)
Saint Joseph's Medical Center Stockton, California
Saint Luke's Cancer Institute - Boise Boise, Idaho	Site Public Contact - (eslinget@slhs.org)
Saint Luke's Cancer Institute - Fruitland Fruitland, Idaho	Site Public Contact - (eslinget@slhs.org)
Saint Luke's Cancer Institute - Meridian Meridian, Idaho	Site Public Contact - (eslinget@slhs.org)
Saint Luke's Cancer Institute - Nampa Nampa, Idaho	Site Public Contact - (eslinget@slhs.org)
Saint Luke's Cancer Institute - Twin Falls Twin Falls, Idaho	Site Public Contact - (eslinget@slhs.org)
Saint Mary Corwin Medical Center Pueblo, Colorado	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Saint Mary Medical Center Hobart, Indiana	Site Public Contact - (CancerResearch@COMHS.org)
Saint Mary's Hospital Centralia, Illinois
Saint Mary's Hospital and Regional Medical Center Grand Junction, Colorado	Site Public Contact - (ccrp@co-cancerresearch.org)
Saint Mary's Oncology/Hematology Associates of Marlette Marlette, Michigan
Saint Mary's Oncology/Hematology Associates of West Branch West Branch, Michigan
Saint Mary's Regional Medical Center Reno, Nevada	Site Public Contact - (research@sncrf.org)
Saint Michael Cancer Center Silverdale, Washington	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Saint Patrick Hospital - Community Hospital Missoula, Montana	Site Public Contact - (amy.hanneman@providence.org)
Saint Vincent Hospital Erie, Pennsylvania
Saint Vincent Hospital Cancer Center Green Bay Green Bay, Wisconsin	Site Public Contact - (WI_research_admin@hshs.org)
Saint Vincent Hospital Cancer Center at Saint Mary's Green Bay, Wisconsin	Site Public Contact - (wi_research_admin@hshs.org)
Saint Vincent Hospital Cancer Center at Sheboygan Sheboygan, Wisconsin	Site Public Contact - (wi_research_admin@hshs.org)
Saint Vincent Hospital Cancer Center at Sturgeon Bay Sturgeon Bay, Wisconsin	Site Public Contact - (wi_research_admin@hshs.org)
Sainte Genevieve County Memorial Hospital Sainte Genevieve, Missouri
Salinas Valley Memorial Salinas, California	Site Public Contact - (tnielsen2@svmh.com)
San Juan City Hospital San Juan,
San Juan Community Oncology Group San Juan,
Sanford Bismarck Medical Center Bismarck, North Dakota	Site Public Contact - (OncologyClinicalTrialsFargo@sanfordhealth.org)
Sanford Broadway Medical Center Fargo, North Dakota	Site Public Contact - (OncologyClinicalTrialsFargo@sanfordhealth.org)
Sanford Cancer Center Oncology Clinic Sioux Falls, South Dakota	Site Public Contact - (OncologyClinicTrialsSF@sanfordhealth.org)
Sanford Joe Lueken Cancer Center Bemidji, Minnesota	Site Public Contact - (OncologyClinicalTrialsFargo@sanfordhealth.org)
Sanford Roger Maris Cancer Center Fargo, North Dakota	Site Public Contact - (OncologyClinicalTrialsFargo@sanfordhealth.org)
Sanford USD Medical Center - Sioux Falls Sioux Falls, South Dakota	Site Public Contact - (OncologyClinicalTrialsSF@SanfordHealth.org)
Scott and White Healthcare Round Rock Round Rock, Texas	Site Public Contact - (ctsucontact@westat.com)
Scott and White Memorial Hospital Temple, Texas
Sidney Kimmel Cancer Center Washington Township Sewell, New Jersey	Site Public Contact - (ONCTrialNow@jefferson.edu)
Sinai Hospital of Baltimore Baltimore, Maryland
Skagit Regional Health Cancer Care Center Mount Vernon, Washington	Site Public Contact - (rcccclinicalresearch@skagitvalleyhospital.org)
Solinsky Center for Cancer Care Manchester, New Hampshire
Southern Illinois University School of Medicine Springfield, Illinois
Sovah Health Martinsville Martinsville, Virginia	Site Public Contact - (sharon.hubbard@lpnt.net)
Spartanburg Medical Center Spartanburg, South Carolina	Site Public Contact - (kmertz-rivera@gibbscc.org)
Springfield Clinic Springfield, Illinois
Springfield Memorial Hospital Springfield, Illinois	Site Public Contact - (pallante.beth@mhsil.com)
State University of New York Upstate Medical University Syracuse, New York
Straub Clinic and Hospital Honolulu, Hawaii
Summerlin Hospital Medical Center Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
Swedish Cancer Institute-Edmonds Edmonds, Washington	Site Public Contact - (PCRC-NCORP@Swedish.org)
Swedish Cancer Institute-Issaquah Issaquah, Washington	Site Public Contact - (PCRC-NCORP@Swedish.org)
Swedish Medical Center-Ballard Campus Seattle, Washington	Site Public Contact - (PCRC-NCORP@Swedish.org)
Swedish Medical Center-First Hill Seattle, Washington	Site Public Contact - (PCRC-NCORP@Swedish.org)
Tampa General Hospital Tampa, Florida	Site Public Contact - (syapchanyk@tgh.org)
Tarrant County Hospital District/JPS Health Network Fort Worth, Texas	Site Public Contact - (macosta02@jpshealth.org)
The Cancer Center of Hawaii-Liliha Honolulu, Hawaii
The Cancer Center of Hawaii-Pali Momi ‘Aiea, Hawaii
The Community Hospital Munster, Indiana
The Dana-Farber Cancer Institute at Londonderry Londonderry, New Hampshire
The Don and Sybil Harrington Cancer Center Amarillo, Texas	Site Public Contact - (Gina.Cravey@bsahs.org)
The Hospital of Central Connecticut New Britain, Connecticut
The James Graham Brown Cancer Center at University of Louisville Louisville, Kentucky
The New York Hospital Medical Center of Queens Flushing, New York
The Queen's Medical Center - West Oahu ‘Ewa Beach, Hawaii	Site Public Contact - (rohta@queens.org)
The Valley Hospital - Luckow Pavilion Paramus, New Jersey	Site Public Contact - (clinicaltrialsresearch@valleyhealth.com)
The West Clinic - Wolf River Germantown, Tennessee	Site Public Contact - (afletcher@westclinic.com)
Thomas Jefferson University Hospital Philadelphia, Pennsylvania	Site Public Contact - (ONCTrialNow@jefferson.edu)
Tidelands Georgetown Memorial Hospital Georgetown, South Carolina	Site Public Contact - (broe@tidelandshealth.org)
Trinity Health IHA Medical Group Hematology Oncology - Brighton Brighton, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
Trinity Health IHA Medical Group Hematology Oncology - Canton Canton, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital Chelsea, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus Ypsilanti, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
Trinity Health Medical Center - Brighton Brighton, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
Trinity Health Medical Center - Canton Canton, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
Trinity Health Saint Joseph Mercy Hospital Ann Arbor Ann Arbor, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
Trinity Health Saint Joseph Mercy Oakland Hospital Pontiac, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
Trinity Health Saint Mary Mercy Livonia Hospital Livonia, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
UC Comprehensive Cancer Center at Silver Cross New Lenox, Illinois	Site Public Contact - (cancerclinicaltrials@bsd.uchicago.edu)
UC Irvine Health/Chao Family Comprehensive Cancer Center Orange, California	Site Public Contact - (ucstudy@uci.edu)
UCHealth - Cherry Creek Denver, Colorado	Site Public Contact - (protocols@AllianceNCTN.org)
UCHealth Highlands Ranch Hospital Highlands Ranch, Colorado
UCHealth Memorial Hospital Central Colorado Springs, Colorado
UCHealth University of Colorado Hospital Aurora, Colorado
UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care Irvine, California	Site Public Contact - (ucstudy@uci.edu)
UI Health Care Mission Cancer and Blood - Ankeny Clinic Ankeny, Iowa
UI Health Care Mission Cancer and Blood - Des Moines Clinic Des Moines, Iowa
UI Health Care Mission Cancer and Blood - Laurel Clinic Des Moines, Iowa
UI Health Care Mission Cancer and Blood - Waukee Clinic Waukee, Iowa
UI Health Care Mission Cancer and Blood - West Des Moines Clinic Clive, Iowa
UNC Lineberger Comprehensive Cancer Center Chapel Hill, North Carolina	Site Public Contact - (cancerclinicaltrials@med.unc.edu)
UPMC Altoona Altoona, Pennsylvania	Site Public Contact - (protocols@AllianceNCTN.org)
UPMC Camp Hill Camp Hill, Pennsylvania
UPMC Cancer Center - Monroeville Monroeville, Pennsylvania	Site Public Contact - (protocols@AllianceNCTN.org)
UPMC Cancer Center at UPMC Horizon Farrell, Pennsylvania	Site Public Contact - (protocols@AllianceNCTN.org)
UPMC Cancer Center at UPMC McKeesport McKeesport, Pennsylvania
UPMC Cancer Center at UPMC Northwest Seneca, Pennsylvania
UPMC Cancer Center-Natrona Heights Natrona Heights, Pennsylvania
UPMC Cancer Center-Uniontown Uniontown, Pennsylvania	Site Public Contact - (protocols@AllianceNCTN.org)
UPMC Cancer Center-Washington Washington, Pennsylvania	Site Public Contact - (protocols@AllianceNCTN.org)
UPMC Cancer Centers - Arnold Palmer Pavilion Greensburg, Pennsylvania
UPMC Hillman Cancer Center - Monroeville Monroeville, Pennsylvania	Site Public Contact - (haneydl@upmc.edu)
UPMC Hillman Cancer Center - New Castle New Castle, Pennsylvania	Site Public Contact - (haneydl@upmc.edu)
UPMC Hillman Cancer Center - Part of Frick Hospital Mount Pleasant, Pennsylvania	Site Public Contact - (haneydl@upmc.edu)
UPMC Hillman Cancer Center Erie Erie, Pennsylvania	Site Public Contact - (haneydl@upmc.edu)
UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion Mechanicsburg, Pennsylvania	Site Public Contact - (haneydl@upmc.edu)
UPMC Hillman Cancer Center in Coraopolis Moon Township, Pennsylvania	Site Public Contact - (haneydl@upmc.edu)
UPMC Hillman Cancer Center in Greenville/UPMC Horizon Greenville, Pennsylvania	Site Public Contact - (haneydl@upmc.edu)
UPMC Memorial York, Pennsylvania
UPMC Pinnacle Cancer Center/Community Osteopathic Campus Harrisburg, Pennsylvania	Site Public Contact - (klitchfield@PINNACLEHEALTH.org)
UPMC Uniontown Hospital Radiation Oncology Uniontown, Pennsylvania
UPMC Washington Hospital Radiation Oncology Washington, Pennsylvania	Site Public Contact - (cancer@washingtonhospital.org)
UPMC Western Maryland Cumberland, Maryland
UPMC-Heritage Valley Health System Beaver Beaver, Pennsylvania	Site Public Contact - (haneydl@upmc.edu)
UPMC-Johnstown/John P. Murtha Regional Cancer Center Johnstown, Pennsylvania
UPMC-Magee Womens Hospital Pittsburgh, Pennsylvania
UPMC-Mercy Hospital Pittsburgh, Pennsylvania
UPMC-Passavant Hospital Pittsburgh, Pennsylvania
UPMC-Saint Clair Hospital Cancer Center Pittsburgh, Pennsylvania
UPMC-Saint Margaret Pittsburgh, Pennsylvania
UPMC-Shadyside Hospital Pittsburgh, Pennsylvania
USC / Norris Comprehensive Cancer Center Los Angeles, California
USC Norris Oncology/Hematology-Newport Beach Newport Beach, California
UT Southwestern Clinical Center at Richardson/Plano Richardson, Texas	Site Public Contact - (Suzanne.cole@utsouthwestern.edu)
UT Southwestern Simmons Cancer Center - RedBird Dallas, Texas	Site Public Contact - (canceranswerline@utsouthwestern.edu)
UT Southwestern/Simmons Cancer Center-Dallas Dallas, Texas	Site Public Contact - (canceranswerline@UTSouthwestern.edu)
UT Southwestern/Simmons Cancer Center-Fort Worth Fort Worth, Texas	Site Public Contact - (canceranswerline@UTSouthwestern.edu)
UW Cancer Center at ProHealth Care Waukesha, Wisconsin	Site Public Contact - (Chanda.miller@phci.org)
United Hospital Saint Paul, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
United Hospital Center Bridgeport, West Virginia	Site Public Contact - (cancertrialsinfo@hsc.wvu.edu)
University Medical Center New Orleans New Orleans, Louisiana	Site Public Contact - (emede1@lsuhsc.edu)
University of Alabama at Birmingham Cancer Center Birmingham, Alabama	Site Public Contact - (tmyrick@uab.edu)
University of Arkansas for Medical Sciences Little Rock, Arkansas
University of California Davis Comprehensive Cancer Center Sacramento, California
University of Chicago Comprehensive Cancer Center Chicago, Illinois	Site Public Contact - (cancerclinicaltrials@bsd.uchicago.edu)
University of Chicago Medicine-Orland Park Orland Park, Illinois	Site Public Contact - (cancerclinicaltrials@bsd.uchicago.edu)
University of Florida Health Science Center - Gainesville Gainesville, Florida
University of Hawaii Cancer Center Honolulu, Hawaii
University of Kentucky/Markey Cancer Center Lexington, Kentucky
University of Michigan - Brighton Center for Specialty Care Brighton, Michigan
University of Michigan Comprehensive Cancer Center Ann Arbor, Michigan	Site Public Contact - (slusserb@med.umich.edu)
University of Michigan Health - Sparrow Lansing Lansing, Michigan	Site Public Contact - (harsha.trivedi@umhsparrow.org)
University of New Mexico Cancer Center Albuquerque, New Mexico	Site Public Contact - (HSC-ClinicalTrialInfo@salud.unm.edu)
University of North Carolina-Hillsborough Campus Hillsborough, North Carolina	Site Public Contact - (cancerclinicaltrials@med.unc.edu)
University of Oklahoma Health Sciences Center Oklahoma City, Oklahoma	Site Public Contact - (ou-clinical-trials@ouhsc.edu)
University of Pittsburgh Cancer Institute (UPCI) Pittsburgh, Pennsylvania
University of Rochester Rochester, New York
University of South Alabama Mitchell Cancer Institute Mobile, Alabama	Site Public Contact - (pfrancisco@usouthal.edu)
University of Texas Health Science Center at San Antonio San Antonio, Texas	Site Public Contact - (phoresearchoffice@uthscsa.edu)
University of Utah Sugarhouse Health Center Salt Lake City, Utah	Site Public Contact - (cancerinfo@hci.utah.edu)
University of Vermont Medical Center Burlington, Vermont	Site Public Contact - (rpo@uvm.edu)
University of Vermont and State Agricultural College Burlington, Vermont	Site Public Contact - (rpo@uvm.edu)
University of Virginia Cancer Center Charlottesville, Virginia	Site Public Contact - (uvacancertrials@hscmail.mcc.virginia.edu)
University of Washington Medical Center - Montlake Seattle, Washington
UofL Health Medical Center Northeast Louisville, Kentucky	Site Public Contact - (ctoinfo@louisville.edu)
Upstate Cancer Center at Oswego Oswego, New York	Site Public Contact - (McDowelE@upstate.edu)
Upstate Cancer Center at Verona Verona, New York	Site Public Contact - (McDowelE@upstate.edu)
VCU Massey Cancer Center at Stony Point Richmond, Virginia	Site Public Contact - (ctoclinops@vcu.edu)
Valley Health System Ridgewood Campus Ridgewood, New Jersey	Site Public Contact - (clinicaltrialsresearch@valleyhealth.com)
Valley Health System-Hematology/Oncology Westwood, New Jersey	Site Public Contact - (protocols@AllianceNCTN.org)
Valley Medical Center Renton, Washington	Site Public Contact - (research@valleymed.org)
Valley Radiation Oncology Peru, Illinois
Vanderbilt Breast Center at One Hundred Oaks Nashville, Tennessee
Vanderbilt University/Ingram Cancer Center Nashville, Tennessee
Vince Lombardi Cancer Clinic - Oshkosh Oshkosh, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Vince Lombardi Cancer Clinic-Sheboygan Sheboygan, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Vince Lombardi Cancer Clinic-Two Rivers Two Rivers, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Virginia Cancer Institute Richmond, Virginia	Site Public Contact - (smoore@vacancer.com)
Virginia Commonwealth University/Massey Cancer Center Richmond, Virginia	Site Public Contact - (CTOclinops@vcu.edu)
Virginia Mason Medical Center Seattle, Washington	Site Public Contact - (cancerresearch@virginiamason.org)
Wake Forest Baptist Health - Wilkes Medical Center Wilkesboro, North Carolina
Wake Forest University Health Sciences Winston-Salem, North Carolina
Wake Forest University at Clemmons Clemmons, North Carolina
Washington Hospital Fremont, California
Wayne Hospital Greenville, Ohio	Site Public Contact - (clinical.trials@daytonncorp.org)
Welch Cancer Center Sheridan, Wyoming
West Penn Hospital Pittsburgh, Pennsylvania
West Virginia University Healthcare Morgantown, West Virginia	Site Public Contact - (cancertrialsinfo@hsc.wvu.edu)
Western Illinois Cancer Treatment Center Galesburg, Illinois
Wexford Health and Wellness Pavilion Wexford, Pennsylvania	Site Public Contact - (Dawnmarie.DeFazio@ahn.org)
Wilcox Memorial Hospital and Kauai Medical Clinic Lihue, Hawaii
William E Kahlert Regional Cancer Center/Sinai Hospital Westminster, Maryland
Wilmot Cancer Institute at Webster Webster, New York	Site Public Contact - (WCICTOresearch@urmc.rochester.edu)
Women's Diagnostic Center - Munster Munster, Indiana	Site Public Contact - (mnicholson@comhs.org)
Woodland Memorial Hospital Woodland, California	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)

GZ17-6.02 in Advanced CRPC After Progression on Anti-Androgen Therapy

Contact(s):

Massey IIT Research Operations - masseyepd@vcu.edu

Principal Investigator:

System ID: NCT06636123

Show full eligibility criteria

Inclusion Criteria:

* Patients diagnosed with prostate cancer and treated with androgen deprivation therapy (ADT) and at least one androgen receptor pathway inhibitor (ARPI) (eg, abiraterone, enzalutamide, apalutamide or darolutamide). Previous prostate-specific membrane antigen (PSMA)-targeted therapy or cytotoxic chemotherapy is allowed but not required. * Androgen levels ≤50 ng/dL (≤1.73 nmol/L). * Disease progression following ADT and ARPI treatment described * PSA progression over 2 assessments, defined as rising PSA values from 2 consecutive assessments with an interval of at least 7 days between assessments. PSA levels prior to study enrollment are considered and appropriate for inclusion. * Measurable disease by RECIST v1.1 on chest/abdomen/pelvis CT or evaluable disease observed on bone scan. * Eastern Cooperative Oncology Group (ECOG) performance status 0, 1, or 2 * Appropriate hepatic function defined by a total bilirubin (TBL) ≤1.5 × the upper limit of normal (ULN), alanine aminotransferase (ALT) AND aspartate aminotransferase (AST) ≤3 × ULN at screening. * Appropriate kidney function defined by calculated or actual creatinine clearance ≥30 mL/min * Absolute neutrophil count (ANC) ≥ 1,500 cells/mm3. * Platelets ≥100,000 cells/mm3. * Serum hemoglobin level ≥9 g/dL. * Agree to not donate blood or sperm during the study and for 90 days after the last dose of study treatment. * Patients with sexual partners of childbearing potential must agree to use highly effective methods of contraception throughout the study * Ability to understand and the willingness to sign a written informed consent document

Exclusion Criteria:

* Any investigational agent: within 4 weeks OR within a time interval less than at least 5 half-lives of the investigational agent, whichever is shorter, before initiating study treatment. * Low PSA (≤10 ng/mL) at initial presentation (before ADT or at symptomatic progression in the castrate setting) plus high volume (≥20) bone metastases. * Simultaneous enrollment in any other cancer treatment interventional clinical trial. * Active, uncontrolled diarrhea leading to dehydration or electrolyte disturbances not controlled with oral repletion. * Grade ≥3 uncontrolled infection. * Major surgery (in the opinion of the treating investigator) ≤3 weeks before initiating study treatment. * Not having fully recovered to a grade of 1 or lower from any surgery-related adverse effects within the 3 weeks preceding the start of the study treatment. * Small cell, anaplastic, or neuroendocrine component. * Known active brain metastasis. * Known active leptomeningeal disease. * Planned ongoing treatment with other drugs thought to potentially have adverse interactions with either of the medications included in the study treatment must be discontinued ≥2 weeks prior to initiating study treatment unless otherwise noted: * Monoamine oxidase inhibitors (MAOI) use; must discontinue use 10 days prior to initiating study therapy. * Strong or moderate CYP1A2, CYP3A4 and CYP2C19 inhibitors. * Rucaparib, Olaparib and Talazoparib, due to their common findings of liver enzyme elevation. * Inability to swallow medication. * Known hypersensitivity to GZ17-6.02 components (curcumin, harmine, and isovanillin) or excipients. * Known or suspected malabsorption condition or obstruction. * Active untreated hepatitis B or C" and "Known liver cirrhosis of any cause, active nonalcoholic steatohepatitis, or nonalcoholic fatty liver disease. Note: no additional testing necessary to confirm * Medical, psychological, or social condition that, in the opinion of the investigator, may increase the patient's risk or limit the patient's adherence with study requirements

Interventions: DRUG: Investigational Agent Administration

Conditions: Castration-resistant Prostate Cancer

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Virginia Commonwealth University Richmond, Virginia	Massey CTO GU Team - (masseygu@vcu.edu)

Study of ATX-01 in Participants With DM1 (ArthemiR)

Contact(s):

Project Manager - clinical@arthexbiotech.com

Principal Investigator:

System ID: NCT06300307

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Interventions: DRUG: ATX-01, DRUG: Placebo

Conditions: Myotonic Dystrophy 1

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Centre Intégré Universitaire de Santé et Services Sociaux du Saguenay-Lac-St-Jean Chicoutimi, Quebec	Sabrina Côté - (sabrina.cote.inf@ssss.gouv.qc.ca)
Fondazione Policlinico A. Gemelli- IRCCS Rome,	Professor - (marika.pane@policlinicogemelli.it)
Hospital Universitario Donostia San Sebastián, Guipuzkoa	Ioana Croitoru - (IOANA.CROITORU@bio-gipuzkoa.eus)
Institute of Myology Paris,	Study Co-ordinator - (essais-adultes@institut-myologie.org)
St. George's University Hospital London,	Joana Teixeira - (Joana.Teixeira@stgeorges.nhs.uk)
The NeMO Clinical Center in Milan, Neurorehabilitation Unit, University of Milan Milan,	Clinical Research Co-ordinator - (crc_rsu@centrocliniconemo.it)
University of Florida Gainesville, Florida	Beverly (Mackenzie) Brooks, ACRP-CCRC - (beverly.brooks@neurology.ufl.edu)
University of Kansas Medical Center, Department of Neurology Fairway, Kansas	Cassidy Nelson - (cnelson15@kumc.edu)
Virginia Commonwealth University Richmond, Virginia	Jodie Howell - (jodie.howell@vcuhealth.org)

Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab

Contact(s):

Sara Tolaney, MD - Sara_Tolaney@dfci.harvard.edu

Principal Investigator:

System ID: NCT05812807

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Inclusion Criteria:

* Age \>= 18 years * Eastern Cooperative Oncology Group (ECOG) Performance Status 0-2 * Triple Negative Breast Cancer: * Patients with a history of stage T1cN1-2 or T2-4N0-2 breast cancer according to the primary tumor-regional lymph node anatomic staging criteria of the American Joint Committee on Cancer (AJCC), 8th edition as determined by the investigator in radiologic assessment, clinical assessment or both * Patients must have no residual invasive disease in the breast or lymph nodes after the completion of neoadjuvant therapy. Residual ductal carcinoma in situ (DCIS) is allowed. Isolated tumor cells are considered node-negative * Estrogen (ER) and progesterone (PR) =\< 10%; HER2-negative by American Society of Clinical Oncology (ASCO)/College of American Pathologists (CAP) guidelines (immunohistochemistry \[IHC\] and fluorescence in situ hybridization \[FISH\]) * If invasive disease was present in both breasts, participation in the study is permitted as long as the eligibility criteria are met for both tumors/breasts * Patients must have received neoadjuvant chemotherapy in combination with pembrolizumab for a minimum of 6 cycles. All systemic chemotherapy and ICI therapy should have been completed preoperatively * An interval of no more than 12 weeks between the completion date of the final surgery and the date of randomization \* Note: Adjuvant radiation can be given on study. If given, it is encouraged to be given concurrently with pembrolizumab, per investigator discretion. Treatment with adjuvant pembrolizumab is strongly discouraged prior to participation in this trial, but if administered (e.g., if patients are awaiting pathology results), pembrolizumab may be administered for up to 6 weeks post-surgery and must be completed prior to registration * Use of investigational anti-cancer agents must be discontinued at time of registration * Adequate excision: Surgical removal of all clinically evident disease in the breast and lymph nodes as follows: * Breast surgery: Total mastectomy or breast-conserving surgery with histologically negative margins, including no ink on tumor for DCIS, at the time of excision \*\* For patients who undergo breast-conserving surgery, the margins of the resected specimen must be histologically free of ductal carcinoma in-situ (DCIS) as determined by the local pathologist. If pathologic examination demonstrates DCIS at the line of resection, additional operative procedures may be performed to obtain clear margins. If DCIS is still present at the resected margin after re-excision(s), the patient must undergo total mastectomy to be eligible. Patients with margins positive for classic lobular carcinoma in situ (LCIS) are eligible without additional resection * Lymph node surgery: * For a patient with clinically N0 disease, a sentinel lymph node biopsy should have been performed at time of surgical evaluation, and if pathologically node positive, the patient is no longer eligible. Isolated tumor cells are considered node-negative * For a patient with clinically N1 disease at diagnosis (with positive results from a fine-needle aspiration, core biopsy, or sentinel node biopsy performed prior to preoperative therapy) additional surgical evaluation of the axilla following preoperative therapy is required \*\*\* If they become cN0 (no palpable adenopathy), then a sentinel lymph node biopsy could have been performed at time of surgery (axillary dissection would also be permitted); if the sentinel lymph node biopsy is positive, the patient is no longer eligible * If sentinel node biopsy performed before preoperative therapy was negative, no additional surgical evaluation of the axilla is required after preoperative therapy. If sentinel node biopsy performed before preoperative therapy was positive, an ALND is required after preoperative therapy * If the only sentinel node identified by isotope scan is in the internal mammary chain, surgical evaluation of the axilla is still required * If sentinel node evaluation after preoperative therapy is negative, no further additional surgical evaluation of the axilla is required * Axillary dissection without sentinel node evaluation is permitted as the initial or sole axillary evaluation after preoperative therapy * If breast-conserving surgery was performed but patient will not be receiving breast radiation, the patient is not eligible * Not pregnant and not nursing, because this study involves an agent whose genotoxic, mutagenic and teratogenic effects on the developing fetus and newborn are unknown. Therefore, for women of childbearing potential only, a negative serum or urine pregnancy test done =\< 7 days prior to randomization is required * Absolute neutrophil count (ANC) \>= 1,000/mm\^3 * Platelet Count \>= 100,000/mm\^3 * Estimated glomerular filtration rate (eGFR) \>= 15 mL/min/1.73m\^2 * Total Bilirubin =\<1.5 x upper limit of normal (ULN) \* Patients with Gilbert's disease with a total bilirubin =\< 2.5 x ULN and direct bilirubin within normal limits are permitted * Aspartate aminotransferase (AST) serum aspartate aminotransferase \[SGOT\] / alanine aminotransferase (ALT) serum glutamic pyruvic transaminase \[SGPT\] =\< 3 x institutional ULN * Patients must be willing to provide tumor tissue from the diagnostic core biopsy. If inadequate tumor tissue is available, patients are still eligible to participate in the trial * Patients with a prior or concurrent malignancy whose natural history or treatment does not have the potential to interfere with the safety or efficacy assessment of the investigational regimen are eligible for this trial * Patients with known history or current symptoms of cardiac disease, or history of treatment with cardiotoxic agents, should have a clinical risk assessment of cardiac function using the New York Heart Association Functional Classification. To be eligible for this trial, patients should be class 2B or better * Human immunodeficiency virus (HIV)-infected patients on effective anti-retroviral therapy with undetectable viral load within 6 months prior to registration are eligible for this trial

Exclusion Criteria:

* No stage IV (metastatic) breast cancer * No history of any prior (ipsi- or contralateral) invasive breast cancer. Prior DCIS is allowed * No evidence of recurrent disease following preoperative therapy and surgery * No known active liver disease, e.g. due to hepatitis B virus (HBV), hepatitis C virus (HCV), autoimmune hepatic disorders, or sclerosing cholangitis * No history of intolerance, including Grade 3 or 4 infusion reaction or hypersensitivity to pembrolizumab or murine proteins or any components of the product \* Note: Prior immune-related adverse events (irAEs) are allowed if they resolved and the patient tolerated subsequent therapy without requiring chronic steroids for the irAE * No medical conditions that require chronic systemic steroids (\>10 mg prednisone daily or equivalent) or any other form of immunosuppressive medications and has required such therapy in the last two years. Replacement therapy (e.g. thyroxine, insulin, or physiologic corticosteroid replacement therapy for adrenal or pituitary insufficiency, etc.) is not considered a form of systemic therapy * Patients who are unable or unwilling to comply with the requirements of the protocol per investigator assessment are not eligible

Interventions: BIOLOGICAL: Pembrolizumab, OTHER: Patient Observation, PROCEDURE: Biopsy, PROCEDURE: Biospecimen Collection, OTHER: Questionnaire Administration, OTHER: Quality-of-Life Assessment

Conditions: Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Early Stage Triple-Negative Breast Carcinoma

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AMG Crystal Lake - Oncology Crystal Lake, Illinois	Site Public Contact - (advocateresearch@advocate.com)
AMG Libertyville - Oncology Libertyville, Illinois	Site Public Contact - (advocateresearch@advocatehealth.com)
Abbott-Northwestern Hospital Minneapolis, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Adams Cancer Center Gettysburg, Pennsylvania
Adena Regional Medical Center Chillicothe, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
AdventHealth Altamonte Altamonte Springs, Florida
AdventHealth Littleton Littleton, Colorado	Site Public Contact - (research.institute@adventhealth.com)
AdventHealth Orlando Orlando, Florida
AdventHealth Parker Parker, Colorado	Site Public Contact - (research.institute@adventhealth.com)
AdventHealth Porter Denver, Colorado	Site Public Contact - (research.institute@adventhealth.com)
Advocate Christ Medical Center Oak Lawn, Illinois
Advocate Good Samaritan Hospital Downers Grove, Illinois	Site Public Contact - (Barbara.barhamand@advocatehealth.com)
Advocate Good Shepherd Hospital Barrington, Illinois
Advocate Illinois Masonic Medical Center Chicago, Illinois
Advocate Lutheran General Hospital Park Ridge, Illinois
Advocate Outpatient Center - Aurora Aurora, Illinois	Site Public Contact - (ncorp@aah.org)
Advocate Sherman Hospital Elgin, Illinois
Advocate South Suburban Hospital Hazel Crest, Illinois
Allan Blair Cancer Centre Regina, Saskatchewan
Allegheny General Hospital Pittsburgh, Pennsylvania
Allegiance Health Jackson, Michigan	Site Public Contact - (CTOResearch@hfhs.org)
Annie Penn Memorial Hospital Reidsville, North Carolina	Site Public Contact - (stacey.phelps@conehealth.com)
Asante Rogue Regional Medical Center Medford, Oregon	Site Public Contact - (research@asante.org)
Ascension All Saints Hospital Racine, Wisconsin	Site Public Contact - (AWRI.Inquiry@Ascension.org)
Ascension Calumet Hospital Chilton, Wisconsin	Site Public Contact - (AWRI.inquiry@ascension.org)
Ascension Columbia Saint Mary's Hospital - Milwaukee Milwaukee, Wisconsin	Site Public Contact - (AWRI.Inquiry@Ascension.org)
Ascension Columbia Saint Mary's Hospital Ozaukee Mequon, Wisconsin	Site Public Contact - (AWRI.Inquiry@Ascension.org)
Ascension Medical Group Southeast Wisconsin - Mayfair Road Wauwatosa, Wisconsin	Site Public Contact - (AWRI.Inquiry@Ascension.org)
Ascension Mercy Hospital Oshkosh, Wisconsin	Site Public Contact - (AWRI.inquiry@ascension.org)
Ascension Saint Elizabeth Hospital Appleton, Wisconsin	Site Public Contact - (AWRI.inquiry@ascension.org)
Ascension Saint Francis - Reiman Cancer Center Franklin, Wisconsin	Site Public Contact - (AWRI.Inquiry@Ascension.org)
Ascension Southeast Wisconsin Hospital - Elmbrook Campus Brookfield, Wisconsin	Site Public Contact - (AWRI.Inquiry@Ascension.org)
Ascension Via Christi Hospitals Wichita Wichita, Kansas	Site Public Contact - (research@viachristi.org)
Aspirus Cancer Care - James Beck Cancer Center Rhinelander, Wisconsin	Site Public Contact - (Beth.Knetter@aspirus.org)
Aspirus Cancer Care - Stevens Point Stevens Point, Wisconsin	Site Public Contact - (Beth.Knetter@aspirus.org)
Aspirus Cancer Care - Wisconsin Rapids Wisconsin Rapids, Wisconsin
Aspirus Medford Hospital Medford, Wisconsin	Site Public Contact - (Beth.Knetter@aspirus.org)
Aspirus Regional Cancer Center Wausau, Wisconsin
Asplundh Cancer Pavilion Willow Grove, Pennsylvania	Site Public Contact - (ONCTrialNow@jefferson.edu)
Atlantic Health Sciences Corporation-Saint John Regional Hospital Saint John, New Brunswick
Atrium Health Cabarrus/LCI-Concord Concord, North Carolina
Atrium Health Cleveland/LCI-Cleveland Shelby, North Carolina
Atrium Health Lincoln/LCI-Lincolnton Lincolnton, North Carolina
Atrium Health Pineville/LCI-Pineville Charlotte, North Carolina
Atrium Health Stanly/LCI-Albemarle Albemarle, North Carolina
Atrium Health Union/LCI-Union Monroe, North Carolina
Atrium Health University City/LCI-University Charlotte, North Carolina
Atrium Medical Center-Middletown Regional Hospital Franklin, Ohio	Site Public Contact - (clinical.trials@daytonncorp.org)
Augusta Health Center for Cancer and Blood Disorders Fishersville, Virginia
Augusta Oncology Associates PC-D'Antignac Augusta, Georgia
Augusta Oncology Associates PC-Wheeler Augusta, Georgia
Aurora Bay Area Medical Group-Marinette Marinette, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Aurora BayCare Medical Center Green Bay, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Aurora Cancer Care-Grafton Grafton, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Aurora Cancer Care-Kenosha South Kenosha, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Aurora Cancer Care-Milwaukee Milwaukee, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Aurora Cancer Care-Milwaukee West Wauwatosa, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Aurora Cancer Care-Racine Racine, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Aurora Cancer Care-Southern Lakes VLCC Burlington, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Aurora Health Care Germantown Health Center Germantown, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Aurora Medical Center in Summit Summit, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Aurora Saint Luke's Medical Center Milwaukee, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Aurora Sinai Medical Center Milwaukee, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Aurora West Allis Medical Center West Allis, Wisconsin	Site Public Contact - (ncorp@aurora.org)
Avera Cancer Institute Sioux Falls, South Dakota	Site Public Contact - (OncRegulatory@avera.org)
Avera Cancer Institute - Mitchell Mitchell, South Dakota	Site Public Contact - (OncRegulatory@avera.org)
Avera Cancer Institute at Pierre Pierre, South Dakota	Site Public Contact - (OncRegulatory@avera.org)
Avera Cancer Institute-Aberdeen Aberdeen, South Dakota	Site Public Contact - (oncregulatory@avera.org)
BCCA-Cancer Centre for the Southern Interior Kelowna, British Columbia
BCCA-Vancouver Cancer Centre Vancouver, British Columbia
BJC Outpatient Center at Sunset Hills Sunset Hills, Missouri
Baptist Cancer Center-Grenada Grenada, Mississippi
Baptist Health Corbin Corbin, Kentucky
Baptist Health Floyd New Albany, Indiana	Site Public Contact - (ctsucontact@westat.com)
Baptist Health Hamburg Lexington, Kentucky
Baptist Health Hardin Elizabethtown, Kentucky
Baptist Health Lexington Lexington, Kentucky
Baptist Health Louisville Louisville, Kentucky	Site Public Contact - (Cbcresearch@bhsi.com)
Baptist MD Anderson Cancer Center Jacksonville, Florida
Baptist Memorial Hospital and Cancer Center-Collierville Collierville, Tennessee	Site Public Contact - (BCCclintrials@bmhcc.org)
Baptist Memorial Hospital and Cancer Center-Desoto Southhaven, Mississippi	Site Public Contact - (BCCclintrials@bmhcc.org)
Baptist Memorial Hospital and Cancer Center-Golden Triangle Columbus, Mississippi	Site Public Contact - (BCCclintrials@bmhcc.org)
Baptist Memorial Hospital and Cancer Center-Memphis Memphis, Tennessee	Site Public Contact - (BCCclintrials@bmhcc.org)
Baptist Memorial Hospital and Cancer Center-Oxford Oxford, Mississippi	Site Public Contact - (BCCclintrials@bmhcc.org)
Baptist Memorial Hospital and Cancer Center-Union County New Albany, Mississippi	Site Public Contact - (BCCclintrials@bmhcc.org)
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center Houston, Texas	Site Public Contact - (burton@bcm.edu)
Baystate Medical Center Springfield, Massachusetts	Site Public Contact - (tamara.wrenn@baystatehealth.org)
Beacon Kalamazoo Cancer Center Kalamazoo, Michigan
Beebe Health Campus Rehoboth Beach, Delaware	Site Public Contact - (research@beebehealthcare.org)
Beebe South Coastal Health Campus Millville, Delaware	Site Public Contact - (research@beebehealthcare.org)
Ben Taub General Hospital Houston, Texas
Benefis Sletten Cancer Institute Great Falls, Montana	Site Public Contact - (mccinfo@mtcancer.org)
Beth Israel Deaconess Medical Center Boston, Massachusetts
Billings Clinic Cancer Center Billings, Montana	Site Public Contact - (research@billingsclinic.org)
Bon Secours Memorial Regional Medical Center Mechanicsville, Virginia	Site Public Contact - (anne_carmellat@bshsi.org)
Bon Secours Saint Francis Medical Center Midlothian, Virginia	Site Public Contact - (anne_carmellat@bshsi.org)
Bon Secours Saint Mary's Hospital Richmond, Virginia	Site Public Contact - (anne_carmellat@bshsi.org)
Boston Medical Center Boston, Massachusetts
Bozeman Health Deaconess Hospital Bozeman, Montana	Site Public Contact - (mccinfo@mtcancer.org)
Broadlawns Medical Center Des Moines, Iowa
Bronson Battle Creek Battle Creek, Michigan	Site Public Contact - (crcwm-regulatory@crcwm.org)
Bronson Methodist Hospital Kalamazoo, Michigan	Site Public Contact - (crcwm-regulatory@crcwm.org)
Broward Health Medical Center Fort Lauderdale, Florida	Site Public Contact - (Allison.bruce@nemours.org)
CHRISTUS Highland Medical Center Shreveport, Louisiana	Site Public Contact - (Nancy.hassan@christushealth.org)
CHU de Quebec-Hopital du Saint-Sacrement (HSS) Québec, Quebec	Site Public Contact - (jbegin@uresp.ulaval.ca)
CTCA at Western Regional Medical Center Goodyear, Arizona
Cambridge Memorial Hospital Cambridge, Ontario
Camden Clark Medical Center Parkersburg, West Virginia	Site Public Contact - (cancertrialsinfo@hsc.wvu.edu)
Cancer Care Associates of York York, Pennsylvania
Cancer Care Center of O'Fallon O'Fallon, Illinois	Site Public Contact - (morganthaler.jodi@mhsil.com)
Cancer Care Specialists of Illinois - Decatur Decatur, Illinois	Site Public Contact - (morganthaler.jodi@mhsil.com)
Cancer Center at Saint Joseph's Phoenix, Arizona	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Cancer Center of Kansas - Chanute Chanute, Kansas	Site Public Contact - (research@viachristi.org)
Cancer Center of Kansas - Dodge City Dodge City, Kansas	Site Public Contact - (research@viachristi.org)
Cancer Center of Kansas - El Dorado El Dorado, Kansas	Site Public Contact - (research@viachristi.org)
Cancer Center of Kansas - McPherson McPherson, Kansas	Site Public Contact - (research@viachristi.org)
Cancer Center of Kansas - Newton Newton, Kansas	Site Public Contact - (research@viachristi.org)
Cancer Center of Kansas - Parsons Parsons, Kansas	Site Public Contact - (research@viachristi.org)
Cancer Center of Kansas - Pratt Pratt, Kansas	Site Public Contact - (research@viachristi.org)
Cancer Center of Kansas - Salina Salina, Kansas	Site Public Contact - (research@viachristi.org)
Cancer Center of Kansas - Wellington Wellington, Kansas	Site Public Contact - (research@viachristi.org)
Cancer Center of Kansas - Wichita Wichita, Kansas	Site Public Contact - (research@viachristi.org)
Cancer Center of Kansas - Winfield Winfield, Kansas	Site Public Contact - (research@viachristi.org)
Cancer Center of Kansas-Independence Independence, Kansas	Site Public Contact - (research@viachristi.org)
Cancer Center of Kansas-Kingman Kingman, Kansas	Site Public Contact - (research@viachristi.org)
Cancer Center of Kansas-Liberal Liberal, Kansas	Site Public Contact - (research@viachristi.org)
Cancer Center of Kansas-Wichita Medical Arts Tower Wichita, Kansas	Site Public Contact - (research@viachristi.org)
Cancer Hematology Centers - Flint Flint, Michigan	Site Public Contact - (wstrong@ghci.org)
Cancer and Hematology Centers of Western Michigan - Norton Shores Norton Shores, Michigan	Site Public Contact - (connie.szczepanek@crcwm.org)
Carle Cancer Center Urbana, Illinois	Site Public Contact - (Research@carle.com)
Carle Physician Group-Effingham Effingham, Illinois	Site Public Contact - (Research@carle.com)
Carle Physician Group-Mattoon/Charleston Mattoon, Illinois	Site Public Contact - (Research@carle.com)
Carle at The Riverfront Danville, Illinois	Site Public Contact - (Research@Carle.com)
Carolinas Medical Center/Levine Cancer Institute Charlotte, North Carolina
Case Western Reserve University Cleveland, Ohio	Site Public Contact - (CTUReferral@UHhospitals.org)
Cedars Sinai Medical Center Los Angeles, California
Cedars-Sinai Cancer - Tarzana Tarzana, California
Centerpoint Medical Center LLC Independence, Missouri
Centra Alan B Pearson Regional Cancer Center Lynchburg, Virginia	Site Public Contact - (Kevin.Patel@centrahealth.com)
Central Vermont Medical Center/National Life Cancer Treatment Berlin Corners, Vermont
Centralia Oncology Clinic Centralia, Illinois	Site Public Contact - (morganthaler.jodi@mhsil.com)
Centre Hospitalier Regional de Trois-Rivieres Trois-Rivières, Quebec
Centro Comprensivo de Cancer de UPR San Juan,
Chelsea Hospital Chelsea, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
Clackamas Radiation Oncology Center Clackamas, Oregon	Site Public Contact - (CanRsrchStudies@providence.org)
Coborn Cancer Center at Saint Cloud Hospital Saint Cloud, Minnesota	Site Public Contact - (coborncancercenter@centracare.com)
Columbus Oncology and Hematology Associates Dublin, Ohio	Site Public Contact - (Jennifer.Sexton@ohiohealth.com)
Columbus Oncology and Hematology Associates Inc Columbus, Ohio	Site Public Contact - (Jennifer.Sexton@ohiohealth.com)
Community Hospital of Anaconda Anaconda, Montana	Site Public Contact - (mccinfo@mtcancer.org)
Community Medical Center Missoula, Montana	Site Public Contact - (mccinfo@mtcancer.org)
Community Medical Center Missoula, Montana	Site Public Contact - (HemonCCTrials@geisinger.edu)
Condell Memorial Hospital Libertyville, Illinois	Site Public Contact - (advocateresearch@advocatehealth.com)
Cone Health Cancer Center Greensboro, North Carolina	Site Public Contact - (stacey.phelps@conehealth.com)
Cone Health Cancer Center at Alamance Regional Burlington, North Carolina	Site Public Contact - (stacey.phelps@conehealth.com)
Cone Health Cancer Center at Asheboro Asheboro, North Carolina
Cone Health Cancer Center at Drawbridge Parkway Greensboro, North Carolina	Site Public Contact - (stacey.phelps@conehealth.com)
Cone Health MedCenter Asheboro Asheboro, North Carolina	Site Public Contact - (stacey.phelps@conehealth.com)
Cooper Hospital University Medical Center Camden, New Jersey
Corewell Health Grand Rapids Hospitals - Butterworth Hospital Grand Rapids, Michigan	Site Public Contact - (crcwm-regulatory@crcwm.org)
Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center Saint Joseph, Michigan	Site Public Contact - (crcwm-regulatory@crcwm.org)
Corewell Health Lakeland Hospitals - Niles Hospital Niles, Michigan
Corewell Health Lakeland Hospitals - Saint Joseph Hospital Saint Joseph, Michigan	Site Public Contact - (crcwm-regulatory@crcwm.org)
Corewell Health Reed City Hospital Reed City, Michigan	Site Public Contact - (crcwm-regulatory@crcwm.org)
CoxHealth South Hospital Springfield, Missouri
Crossroads Cancer Center Effingham, Illinois	Site Public Contact - (morganthaler.jodi@mhsil.com)
Dana Farber-Merrimack Valley Methuen, Massachusetts
Dana-Farber Cancer Institute Boston, Massachusetts
Dana-Farber Cancer Institute at Foxborough Foxborough, Massachusetts
Dana-Farber/Brigham and Women's Cancer Center at South Shore South Weymouth, Massachusetts
Danbury Hospital Danbury, Connecticut
Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center Lebanon, New Hampshire	Site Public Contact - (cancer.research.nurse@dartmouth.edu)
Dayton Physician LLC - Englewood Dayton, Ohio
Decatur Memorial Hospital Decatur, Illinois	Site Public Contact - (morganthaler.jodi@mhsil.com)
Delaware Health Center-Grady Cancer Center Delaware, Ohio	Site Public Contact - (Jennifer.Sexton@ohiohealth.com)
Desert Regional Medical Center Palm Springs, California
Doctors Cancer Center Manatí,
Doctors Hospital Columbus, Ohio	Site Public Contact - (Jennifer.Sexton@ohiohealth.com)
Drexel Town Square Health Center Oak Creek, Wisconsin
Dublin Methodist Hospital Dublin, Ohio	Site Public Contact - (Jennifer.Sexton@ohiohealth.com)
Duke Cancer Center Cary Cary, North Carolina	Site Public Contact - (NCTNStudyTeam@dm.duke.edu)
Duke University Medical Center Durham, North Carolina
Duke Women's Cancer Care Raleigh Raleigh, North Carolina
Duluth Clinic Ashland Ashland, Wisconsin	Site Public Contact - (CancerTrials@EssentiaHealth.org)
East Carolina University Greenville, North Carolina	Site Public Contact - (eubankss@ecu.edu)
Edwards Comprehensive Cancer Center Huntington, West Virginia	Site Public Contact - (Christina.Cole@chhi.org)
Emory Decatur Hospital Decatur, Georgia	Site Public Contact - (clinicaltrialsoncology@dekalbmedical.org)
Emory Johns Creek Hospital Johns Creek, Georgia	Site Public Contact - (m.lisa.hwang@emory.edu)
Emory Saint Joseph's Hospital Atlanta, Georgia
Emory University Hospital Midtown Atlanta, Georgia
Emory University Hospital/Winship Cancer Institute Atlanta, Georgia
Englewood Hospital and Medical Center Englewood, New Jersey
Enloe Medical Center Chico, California
Ephrata Cancer Center Ephrata, Pennsylvania
Essentia Health - Deer River Clinic Deer River, Minnesota	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Essentia Health Cancer Center Duluth, Minnesota	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Essentia Health Cancer Center-South University Clinic Fargo, North Dakota	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Essentia Health Hibbing Clinic Hibbing, Minnesota
Essentia Health Saint Joseph's Medical Center Brainerd, Minnesota	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Essentia Health Sandstone Sandstone, Minnesota	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Essentia Health Virginia Clinic Virginia, Minnesota	Site Public Contact - (CancerTrials@EssentiaHealth.org)
Essentia Health-Spooner Clinic Spooner, Wisconsin	Site Public Contact - (CancerTrials@EssentiaHealth.org)
FHCC Overlake Bellevue, Washington
FHCC at EvergreenHealth Kirkland, Washington
FHCC at Northwest Hospital Seattle, Washington
FMH James M Stockman Cancer Institute Frederick, Maryland
Fairfield Medical Center Lancaster, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
Fairview Southdale Hospital Edina, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Farmington Health Center Farmington, Utah	Site Public Contact - (cancerinfo@hci.utah.edu)
FirstHealth of the Carolinas-Moore Regional Hospital Pinehurst, North Carolina	Site Public Contact - (jcwilliams@firsthealth.org)
Forbes Hospital Monroeville, Pennsylvania
Fred Hutchinson Cancer Center Seattle, Washington
Fred and Pamela Buffett Cancer Center - Kearney Kearney, Nebraska	Site Public Contact - (unmcrsa@unmc.edu)
Fremont - Rideout Cancer Center Marysville, California
Froedtert Menomonee Falls Hospital Menomonee Falls, Wisconsin
Froedtert West Bend Hospital/Kraemer Cancer Center West Bend, Wisconsin
Geisinger Cancer Center Dickson City Dickson City, Pennsylvania	Site Public Contact - (hemoncctrials@geisinger.edu)
Geisinger Medical Center Danville, Pennsylvania	Site Public Contact - (HemonCCTrials@geisinger.edu)
Geisinger Medical Oncology-Lewisburg Lewisburg, Pennsylvania	Site Public Contact - (HemonCCTrials@geisinger.edu)
Geisinger Wyoming Valley/Henry Cancer Center Wilkes-Barre, Pennsylvania	Site Public Contact - (HemonCCTrials@geisinger.edu)
Gene Upshaw Memorial Tahoe Forest Cancer Center Truckee, California
Genesee Hematology Oncology PC Flint, Michigan
Genesis Healthcare System Cancer Care Center Zanesville, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
Genesys Hurley Cancer Institute Flint, Michigan	Site Public Contact - (wstrong@ghci.org)
Good Samaritan Hospital - Cincinnati Cincinnati, Ohio	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Grady Health System Atlanta, Georgia
Grady Memorial Hospital Delaware, Ohio	Site Public Contact - (Jennifer.Sexton@ohiohealth.com)
Grant Medical Center Columbus, Ohio	Site Public Contact - (Jennifer.Sexton@ohiohealth.com)
Greater Baltimore Medical Center Baltimore, Maryland
Gundersen Lutheran Medical Center La Crosse, Wisconsin	Site Public Contact - (cancerctr@gundersenhealth.org)
Guthrie Medical Group PC-Robert Packer Hospital Sayre, Pennsylvania
Hackensack University Medical Center Hackensack, New Jersey
Hartford HealthCare - Saint Vincent's Medical Center Bridgeport, Connecticut
Hartford Hospital Hartford, Connecticut
Hawaii Cancer Care - Westridge ‘Aiea, Hawaii	Site Public Contact - (info@hawaiicancercare.com)
Hawaii Cancer Care Inc - Waterfront Plaza Honolulu, Hawaii	Site Public Contact - (i.webster@hawaiicancercare.com)
HaysMed Hays, Kansas
Health Central Ocoee, Florida	Site Public Contact - (ctsucontact@westat.com)
Heartland Oncology and Hematology LLP Council Bluffs, Iowa
Heartland Regional Medical Center Saint Joseph, Missouri	Site Public Contact - (Trisha.England2@mymlc.com)
Helen F Graham Cancer Center Newark, Delaware	Site Public Contact - (lbarone@christianacare.org)
Hematology Oncology Associates of CNY at Camillus Camillus, New York
Hematology Oncology Associates of Central New York-East Syracuse East Syracuse, New York
Hennepin County Medical Center Minneapolis, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Henry Ford Health Providence Novi Hospital Novi, Michigan	Site Public Contact - (kfife3@hfhs.org)
Henry Ford Health Providence Southfield Hospital Southfield, Michigan	Site Public Contact - (kfife3@hfhs.org)
Henry Ford Health Saint John Hospital Detroit, Michigan	Site Public Contact - (Kkeenan1@hfhs.org)
Henry Ford Health Warren Hospital Warren, Michigan	Site Public Contact - (kforman1@hfhs.org)
Henry Ford Hospital Detroit, Michigan	Site Public Contact - (CTOResearch@hfhs.org)
Henry Ford Macomb Hospital-Clinton Township Clinton Township, Michigan	Site Public Contact - (CTOResearch@hfhs.org)
Henry Ford Madison Heights Hospital - Breast Warren, Michigan	Site Public Contact - (kforman1@hfhs.org)
Henry Ford Medical Center-Columbus Novi, Michigan	Site Public Contact - (CTOResearch@hfhs.org)
Henry Ford River District Hospital East China Township, Michigan	Site Public Contact - (kforman1@hfhs.org)
Henry Ford Saint John Hospital - Academic Grosse Pointe Woods, Michigan	Site Public Contact - (kforman1@hfhs.org)
Henry Ford Saint John Hospital - Breast Grosse Pointe Woods, Michigan	Site Public Contact - (karen.forman@ascension.org)
Henry Ford Saint John Hospital - Macomb Medical Macomb, Michigan	Site Public Contact - (kforman1@hfhs.org)
Henry Ford Saint John Hospital - Van Elslander Grosse Pointe Woods, Michigan	Site Public Contact - (kforman1@hfhs.org)
Henry Ford Warren Hospital - Breast Macomb Macomb, Michigan	Site Public Contact - (kforman1@hfhs.org)
Henry Ford Warren Hospital - GLCMS Warren, Michigan	Site Public Contact - (kforman1@hfhs.org)
Henry Ford West Bloomfield Hospital West Bloomfield, Michigan	Site Public Contact - (CTOResearch@hfhs.org)
Highlands Oncology Group Springdale, Arkansas	Site Public Contact - (research@hogonc.com)
Highlands Oncology Group - Fayetteville Fayetteville, Arkansas	Site Public Contact - (research@hogonc.com)
Highlands Oncology Group - Rogers Rogers, Arkansas	Site Public Contact - (research@hogonc.com)
Houston Methodist Cypress Hospital Cypress, Texas	Site Public Contact - (irb@houstonmethodist.org)
Houston Methodist Hospital Houston, Texas
Houston Methodist Saint John Hospital Nassau Bay, Texas	Site Public Contact - (protocols@AllianceNCTN.org)
Houston Methodist San Jacinto Hospital Baytown, Texas	Site Public Contact - (protocols@AllianceNCTN.org)
Houston Methodist Sugar Land Hospital Sugar Land, Texas
Houston Methodist The Woodlands Hospital The Woodlands, Texas	Site Public Contact - (hmthewoodlands@houstonmethodist.org)
Houston Methodist West Hospital Houston, Texas
Huntington Memorial Hospital Pasadena, California
Huntsman Cancer Institute/University of Utah Salt Lake City, Utah	Site Public Contact - (cancerinfo@hci.utah.edu)
Hurley Medical Center Flint, Michigan	Site Public Contact - (wstrong@ghci.org)
Huron Gastroenterology PC Ypsilanti, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
IU Health North Hospital Carmel, Indiana	Site Public Contact - (iutrials@iu.edu)
IU Health West Hospital Avon, Indiana	Site Public Contact - (iutrials@iu.edu)
Illinois CancerCare - Washington Washington, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Bloomington Bloomington, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Canton Canton, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Carthage Carthage, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Dixon Dixon, Illinois
Illinois CancerCare-Eureka Eureka, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Galesburg Galesburg, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Kewanee Clinic Kewanee, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Macomb Macomb, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Ottawa Clinic Ottawa, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Pekin Pekin, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Peoria Peoria, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Peru Peru, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Illinois CancerCare-Princeton Princeton, Illinois	Site Public Contact - (andersonj@illinoiscancercare.com)
Indiana University/Melvin and Bren Simon Cancer Center Indianapolis, Indiana	Site Public Contact - (iutrials@iu.edu)
Ingalls Memorial Hospital Harvey, Illinois	Site Public Contact - (clinicaltrials@ingalls.org)
Inova Fair Oaks Hospital Fairfax, Virginia	Site Public Contact - (Stephanie.VanBebber@inova.org)
Inova Fairfax Hospital Falls Church, Virginia	Site Public Contact - (Stephanie.VanBebber@inova.org)
Inova Schar Cancer Institute Fairfax, Virginia	Site Public Contact - (Stephanie.VanBebber@inova.org)
Inspira Medical Center Mullica Hill Mullica Hill, New Jersey
Iowa Methodist Medical Center Des Moines, Iowa
Jefferson Cherry Hill Hospital Cherry Hill, New Jersey	Site Public Contact - (ONCTrialNow@jefferson.edu)
Jefferson Hospital Jefferson Hills, Pennsylvania	Site Public Contact - (ddefazio@wpahs.org)
Jefferson Torresdale Hospital Philadelphia, Pennsylvania	Site Public Contact - (ONCTrialNow@jefferson.edu)
Jersey City Medical Center Jersey City, New Jersey	Site Public Contact - (ctsucontact@westat.com)
John H Stroger Jr Hospital of Cook County Chicago, Illinois
Kadlec Clinic Hematology and Oncology Kennewick, Washington	Site Public Contact - (research@kadlecmed.org)
Kaiser Permanente - Largo Medical Center Largo, Maryland	Site Public Contact - (Charmaine.A.Mckie@kp.org)
Kaiser Permanente Downtown Commons Sacramento, California	Site Public Contact - (kpoct@kp.org)
Kaiser Permanente Dublin Dublin, California
Kaiser Permanente Fresno Orchard Plaza Fresno, California
Kaiser Permanente Lutherville - Timonium Medical Center Lutherville, Maryland	Site Public Contact - (Charmaine.A.Mckie@kp.org)
Kaiser Permanente Medical Center - Santa Clara Santa Clara, California	Site Public Contact - (Kpoct@kp.org)
Kaiser Permanente Moanalua Medical Center Honolulu, Hawaii	Site Public Contact - (shelley.a.clark@kp.org)
Kaiser Permanente Northwest Portland, Oregon	Site Public Contact - (information@kpchr.org)
Kaiser Permanente San Leandro San Leandro, California	Site Public Contact - (Kpoct@kp.org)
Kaiser Permanente Tysons Corner Medical Center McLean, Virginia	Site Public Contact - (Charmaine.A.Mckie@kp.org)
Kaiser Permanente-Capitol Hill Medical Center Washington D.C., District of Columbia	Site Public Contact - (Charmaine.A.Mckie@kp.org)
Kaiser Permanente-Caton Hill Medical Center Woodbridge, Virginia	Site Public Contact - (Charmaine.A.Mckie@kp.org)
Kaiser Permanente-Franklin Denver, Colorado	Site Public Contact - (kristi.m.bronkan@kp.org)
Kaiser Permanente-Fremont Fremont, California	Site Public Contact - (Kpoct@kp.org)
Kaiser Permanente-Fresno Fresno, California	Site Public Contact - (Kpoct@kp.org)
Kaiser Permanente-Gaithersburg Medical Center Gaithersburg, Maryland	Site Public Contact - (Charmaine.A.Mckie@kp.org)
Kaiser Permanente-Lone Tree Lone Tree, Colorado	Site Public Contact - (kristi.m.bronkan@kp.org)
Kaiser Permanente-Modesto Modesto, California	Site Public Contact - (Kpoct@kp.org)
Kaiser Permanente-Oakland Oakland, California	Site Public Contact - (Kpoct@kp.org)
Kaiser Permanente-Rock Creek Lafayette, Colorado	Site Public Contact - (kristi.m.bronkan@kp.org)
Kaiser Permanente-Roseville Roseville, California	Site Public Contact - (Kpoct@kp.org)
Kaiser Permanente-San Francisco San Francisco, California	Site Public Contact - (Kpoct@kp.org)
Kaiser Permanente-Santa Rosa Santa Rosa, California	Site Public Contact - (Kpoct@kp.org)
Kaiser Permanente-Santa Teresa-San Jose San Jose, California	Site Public Contact - (Kpoct@kp.org)
Kaiser Permanente-South Sacramento Sacramento, California	Site Public Contact - (Kpoct@kp.org)
Kaiser Permanente-South San Francisco South San Francisco, California	Site Public Contact - (Kpoct@kp.org)
Kaiser Permanente-Vallejo Vallejo, California	Site Public Contact - (Kpoct@kp.org)
Kaiser Permanente-Walnut Creek Walnut Creek, California	Site Public Contact - (Kpoct@kp.org)
Kaiser Permanente-Woodlawn Medical Center Baltimore, Maryland	Site Public Contact - (Charmaine.A.Mckie@kp.org)
Kaiser San Rafael-Gallinas San Rafael, California	Site Public Contact - (Kpoct@kp.org)
Kapiolani Medical Center for Women and Children Honolulu, Hawaii
Katmai Oncology Group Anchorage, Alaska	Site Public Contact - (AKPAMC.OncologyResearchSupport@providence.org)
Kettering Medical Center Kettering, Ohio
Kingman Regional Medical Center Kingman, Arizona	Site Public Contact - (research@sncrf.org)
Kingston Health Sciences Centre Kingston, Ontario	Site Public Contact - (cc-clinicaltrials@kgh.kari.net)
Kootenai Clinic Cancer Services - Post Falls Post Falls, Idaho	Site Public Contact - (mccinfo@mtcancer.org)
Kootenai Clinic Cancer Services - Sandpoint Sandpoint, Idaho	Site Public Contact - (mccinfo@mtcancer.org)
Kootenai Health - Coeur d'Alene Coeur d'Alene, Idaho	Site Public Contact - (mccinfo@mtcancer.org)
Lake Regional Hospital Osage Beach, Missouri	Site Public Contact - (clinicaltrials@lakeregional.com)
Langlade Hospital and Cancer Center Antigo, Wisconsin	Site Public Contact - (Juli.Alford@aspirus.org)
Laura and Isaac Perlmutter Cancer Center at NYU Langone New York, New York	Site Public Contact - (CancerTrials@nyulangone.org)
Lawrence Memorial Hospital Lawrence, Kansas	Site Public Contact - (Stephanie.Norris@LMH.ORG)
Legacy Cancer Institute Medical Oncology and Day Treatment Vancouver, Washington	Site Public Contact - (oncologyresearch@lhs.org)
Legacy Good Samaritan Hospital and Medical Center Portland, Oregon	Site Public Contact - (cancer@lhs.org)
Legacy Meridian Park Hospital Tualatin, Oregon
Legacy Mount Hood Medical Center Gresham, Oregon
Legacy Salmon Creek Hospital Vancouver, Washington
Lehigh Valley Hospital - Muhlenberg Bethlehem, Pennsylvania	Site Public Contact - (Morgan_M.Horton@lvhn.org)
Lehigh Valley Hospital-Cedar Crest Allentown, Pennsylvania	Site Public Contact - (Morgan_M.Horton@lvhn.org)
Lehigh Valley Hospital-Hazleton Hazleton, Pennsylvania	Site Public Contact - (Morgan_M.Horton@lvhn.org)
Lenox Hill Hospital New York, New York
Levine Cancer Institute - Huntersville Huntersville, North Carolina
Levine Cancer Institute - Rutherford Forest City, North Carolina
Levine Cancer Institute - Union West Matthews, North Carolina
Levine Cancer Institute-Ballantyne Charlotte, North Carolina
Levine Cancer Institute-Gaston Gastonia, North Carolina
Levine Cancer Institute-Rock Hill Rock Hill, South Carolina
Levine Cancer Institute-SouthPark Charlotte, North Carolina
Lewis Cancer and Research Pavilion at Saint Joseph's/Candler Savannah, Georgia	Site Public Contact - (underberga@sjchs.org)
Lexington Medical Center West Columbia, South Carolina	Site Public Contact - (research@lexhealth.org)
Licking Memorial Hospital Newark, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
Logan Health Medical Center Kalispell, Montana	Site Public Contact - (mccinfo@mtcancer.org)
Loma Linda University Medical Center Loma Linda, California
London Regional Cancer Program London, Ontario
Louisiana Hematology Oncology Associates Baton Rouge, Louisiana	Site Public Contact - (clinicalresearch@marybird.com)
Louisiana Hematology Oncology Associates LLC Baton Rouge, Louisiana	Site Public Contact - (clinicalresearch@marybird.com)
Loyola University Medical Center Maywood, Illinois
Luminis Health Anne Arundel Medical Center Annapolis, Maryland	Site Public Contact - (research@luminishealth.org)
Lyndon Baines Johnson General Hospital Houston, Texas
M D Anderson Cancer Center Houston, Texas	Site Public Contact - (askmdanderson@mdanderson.org)
MD Anderson League City League City, Texas	Site Public Contact - (askmdanderson@mdanderson.org)
MD Anderson West Houston Houston, Texas	Site Public Contact - (askmdanderson@mdanderson.org)
MD Anderson in Sugar Land Sugar Land, Texas	Site Public Contact - (askmdanderson@mdanderson.org)
MD Anderson in The Woodlands Conroe, Texas	Site Public Contact - (askmdanderson@mdanderson.org)
MU Health - University Hospital/Ellis Fischel Cancer Center Columbia, Missouri
MU Health Care Goldschmidt Cancer Center Jefferson City, Missouri
Maimonides Medical Center Brooklyn, New York
Manhattan Eye Ear and Throat Hospital New York, New York
Margaret R Pardee Memorial Hospital Hendersonville, North Carolina
Marion L Shepard Cancer Center - ECU Health Beaufort Hospital Washington, North Carolina
Marshall Cancer Center Cameron Park, California	Site Public Contact - (cancerservices@marshallmedical.org)
Marshfield Medical Center - Minocqua Minocqua, Wisconsin	Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org)
Marshfield Medical Center - Weston Weston, Wisconsin	Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org)
Marshfield Medical Center-EC Cancer Center Eau Claire, Wisconsin	Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org)
Marshfield Medical Center-Marshfield Marshfield, Wisconsin	Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org)
Marshfield Medical Center-Rice Lake Rice Lake, Wisconsin	Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org)
Marshfield Medical Center-River Region at Stevens Point Stevens Point, Wisconsin	Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org)
Mary Bird Perkins Cancer Center Baton Rouge, Louisiana	Site Public Contact - (clinicalresearch@marybird.com)
Mary Lanning Memorial Hospital Hastings, Nebraska
Mayo Clinic Hospital in Arizona Phoenix, Arizona
Mayo Clinic in Florida Jacksonville, Florida
Mayo Clinic in Rochester Rochester, Minnesota
McLeod Regional Medical Center Florence, South Carolina	Site Public Contact - (dorie.sturgill@mcleodhealth.org)
Mease Countryside Hospital Safety Harbor, Florida	Site Public Contact - (research.cto@baycare.org)
MedStar Georgetown University Hospital Washington D.C., District of Columbia
Medical Center of Baton Rouge Baton Rouge, Louisiana	Site Public Contact - (Camille.Beck@Ochsner.org)
Medical College of Wisconsin Milwaukee, Wisconsin
Medical Oncology Hematology Consultants PA Newark, Delaware	Site Public Contact - (lbarone@christianacare.org)
Medical University of South Carolina Charleston, South Carolina	Site Public Contact - (hcc-clinical-trials@musc.edu)
Medstar Washington Hospital Center Washington D.C., District of Columbia
Memorial Hospital Chattanooga, Tennessee	Site Public Contact - (Jeffh@columbusccop.org)
Memorial Hospital East Shiloh, Illinois	Site Public Contact - (dschwab@wustl.edu)
Memorial Hospital North Colorado Springs, Colorado
Memorial Hospital West Pembroke Pines, Florida
Memorial Hospital of South Bend South Bend, Indiana
Memorial Regional Hospital/Joe DiMaggio Children's Hospital Hollywood, Florida	Site Public Contact - (OHR@mhs.net)
Menorah Medical Center Overland Park, Kansas
Mercy Cancer Center - Carmichael Carmichael, California	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Mercy Cancer Center - Elk Grove Elk Grove, California	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Mercy Cancer Center - Rocklin Rocklin, California	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Mercy Cancer Center - Sacramento Sacramento, California	Site Public Contact - (ResearchInstituteInquiries@CommonSpirit.org)
Mercy Health - Perrysburg Hospital Perrysburg, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
Mercy Health - Saint Anne Hospital Toledo, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
Mercy Hospital Coon Rapids, Minnesota
Mercy Hospital Coon Rapids, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Mercy Hospital Oklahoma City Oklahoma City, Oklahoma
Mercy Hospital Saint Louis St Louis, Missouri
Mercy Hospital South St Louis, Missouri	Site Public Contact - (Danielle.Werle@mercy.net)
Mercy Hospital Springfield Springfield, Missouri
Mercy Oncology and Hematology - Clayton-Clarkson Ballwin, Missouri
Mercy San Juan Medical Center Carmichael, California	Site Public Contact - (OncologyResearch@DignityHealth.org)
Mercyhealth Hospital and Cancer Center - Janesville Janesville, Wisconsin	Site Public Contact - (oncologyclinicaltrials@mhemail.org)
Methodist Jennie Edmundson Hospital Council Bluffs, Iowa	Site Public Contact - (kathryn.bartz@nmhs.org)
Methodist Willowbrook Hospital Houston, Texas	Site Public Contact - (protocols@AllianceNCTN.org)
Miami Valley Cancer Care and Infusion Greenville, Ohio
Miami Valley Hospital North Dayton, Ohio	Site Public Contact - (clinical.trials@daytonncorp.org)
Miami Valley Hospital South Centerville, Ohio	Site Public Contact - (clinical.trials@daytonncorp.org)
Midstate Medical Center Meriden, Connecticut
Mills Health Center San Mateo, California	Site Public Contact - (clinicalresearch@sutterhealth.org)
Minnesota Oncology - Burnsville Burnsville, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Missouri Baptist Medical Center St Louis, Missouri
Missouri Baptist Sullivan Hospital Sullivan, Missouri
Mobile Infirmary Medical Center Mobile, Alabama
Monmouth Medical Center Long Branch, New Jersey	Site Public Contact - (mary.danish@rwjbh.org)
Monmouth Medical Center Southern Campus Lakewood, New Jersey	Site Public Contact - (mary.danish@rwjbh.org)
Montefiore Medical Center-Einstein Campus The Bronx, New York	Site Public Contact - (eskwak@montefiore.org)
Morristown Medical Center Morristown, New Jersey
Morton Plant Hospital Clearwater, Florida
Mount Carmel East Hospital Columbus, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
Mount Carmel Grove City Hospital Grove City, Ohio	Site Public Contact - (Jeffh@columbusccop.org)
Mount Sinai Chelsea New York, New York	Site Public Contact - (CCTO@mssm.edu)
Mount Sinai Hospital New York, New York	Site Public Contact - (CCTO@mssm.edu)
Mount Sinai Medical Center Miami Beach, Florida	Site Public Contact - (yenrique@msmc.com)
Mount Sinai West New York, New York	Site Public Contact - (CCTO@mssm.edu)
Munson Medical Center Traverse City, Michigan	Site Public Contact - (crcwm-regulatory@crcwm.org)
MyMichigan Medical Center Saginaw Saginaw, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
MyMichigan Medical Center Tawas Tawas City, Michigan	Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org)
NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro Jonesboro, Arkansas	Site Public Contact - (Emily.Carvell@bmhcc.org)
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center New York, New York	Site Public Contact - (cancerclinicaltrials@cumc.columbia.edu)
NYU Langone Hospital - Brooklyn Brooklyn, New York	Site Public Contact - (david.wallach@nyulangone.org)
NYU Langone Hospital - Long Island Mineola, New York	Site Public Contact - (cancertrials@nyulangone.org)
Nebraska Cancer Specialists/Oncology Hematology West PC - MECC Omaha, Nebraska
Nebraska Cancer Specialists/Oncology Hematology West PC - MEJ Council Bluffs, Iowa	Site Public Contact - (Liza.brandes@nmhs.org)
Nebraska Medicine-Bellevue Bellevue, Nebraska	Site Public Contact - (unmcrsa@unmc.edu)
Nebraska Medicine-Village Pointe Omaha, Nebraska
Nebraska Methodist Hospital Omaha, Nebraska
New Hampshire Oncology Hematology PA-Concord Concord, New Hampshire
North Memorial Medical Health Center Robbinsdale, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
North Star Lodge Cancer Center at Yakima Valley Memorial Hospital Yakima, Washington	Site Public Contact - (Memorial-ClinicalTrials@yvmh.org)
NorthShore University HealthSystem-Evanston Hospital Evanston, Illinois
NorthShore University HealthSystem-Glenbrook Hospital Glenview, Illinois
NorthShore University HealthSystem-Highland Park Hospital Highland Park, Illinois
Northern Westchester Hospital Mount Kisco, New York	Site Public Contact - (AMellor@northwell.edu)
Northside Hospital Atlanta, Georgia	Site Public Contact - (ClinicalTrials@northside.com)
Northside Hospital - Duluth Duluth, Georgia	Site Public Contact - (Clinical.trials@northside.com)
Northside Hospital - Gwinnett Lawrenceville, Georgia	Site Public Contact - (Clinical.trials@northside.com)
Northwell Health Cancer Institute at Huntington Greenlawn, New York
Northwell Health Imbert Cancer Center Bay Shore, New York
Northwell Health/Center for Advanced Medicine Lake Success, New York
Northwest Cancer Center - Hobart Hobart, Indiana
Northwest Cancer Center - Main Campus Crown Point, Indiana
Northwest Cancer Center - Valparaiso Valparaiso, Indiana	Site Public Contact - (CancerResearch@COMHS.org)
Northwest Oncology LLC Dyer, Indiana
Northwestern Medicine Cancer Center Delnor Geneva, Illinois	Site Public Contact - (Donald.Smith3@nm.org)
Northwestern Medicine Cancer Center Kishwaukee DeKalb, Illinois	Site Public Contact - (Donald.Smith3@nm.org)
Northwestern Medicine Cancer Center Warrenville Warrenville, Illinois	Site Public Contact - (Donald.Smith3@nm.org)
Northwestern Medicine Glenview Outpatient Center Glenview, Illinois
Northwestern Medicine Grayslake Outpatient Center Grayslake, Illinois
Northwestern Medicine Lake Forest Hospital Lake Forest, Illinois	Site Public Contact - (cancertrials@northwestern.edu)
Northwestern Medicine Oak Brook Oak Brook, Illinois	Site Public Contact - (nctnprogram_rhlccc@northwestern.edu)
Northwestern Medicine Orland Park Orland Park, Illinois	Site Public Contact - (nctnprogram_rhlccc@northwestern.edu)
Northwestern University Chicago, Illinois	Site Public Contact - (cancer@northwestern.edu)
Norwalk Hospital Norwalk, Connecticut	Site Public Contact - (jennifer.long@norwalkhealth.org)
Novant Health Cancer Institute - Huntersville Huntersville, North Carolina	Site Public Contact - (kashah@novanthealth.org)
Novant Health Cancer Institute - Kernersville Kernersville, North Carolina	Site Public Contact - (asmarrs@novanthealth.org)
Novant Health Cancer Institute - Matthews Matthews, North Carolina	Site Public Contact - (kashah@novanthealth.org)
Novant Health Cancer Institute - Mooresville Mooresville, North Carolina	Site Public Contact - (kashah@novanthealth.org)
Novant Health Cancer Institute - Mount Airy Mount Airy, North Carolina	Site Public Contact - (asmarrs@novanthealth.org)
Novant Health Cancer Institute - Rowan Salisbury, North Carolina	Site Public Contact - (kashah@novanthealth.org)
Novant Health Cancer Institute - Thomasville Thomasville, North Carolina	Site Public Contact - (pjordan@novanthealth.org)
Novant Health Forsyth Medical Center Winston-Salem, North Carolina	Site Public Contact - (pjordan@novanthealth.org)
Novant Health Presbyterian Medical Center Charlotte, North Carolina	Site Public Contact - (kashah@novanthealth.org)
Novant Health Presbyterian Medical Center Huntersville Huntersville, North Carolina	Site Public Contact - (kashah@novanthealth.org)
OSF Saint Anthony Medical Center Rockford, Illinois
Ochsner Hematology Oncology North Shore - Covington (West Region) Covington, Louisiana	Site Public Contact - (Cheryl.kesler@ochsner.org)
Ochsner High Grove Baton Rouge, Louisiana	Site Public Contact - (Camielle.beck@ochsner.org)
Ochsner Medical Center Jefferson New Orleans, Louisiana	Site Public Contact - (Elisemarie.curry@ochsner.org)
Odette Cancer Centre- Sunnybrook Health Sciences Centre Toronto, Ontario
Ohio State University Comprehensive Cancer Center Columbus, Ohio	Site Public Contact - (Jamesline@osumc.edu)
OhioHealth Mansfield Hospital Mansfield, Ohio	Site Public Contact - (Jennifer.Sexton@ohiohealth.com)
OhioHealth Marion General Hospital Marion, Ohio	Site Public Contact - (Jennifer.Sexton@ohiohealth.com)
OhioHealth O'Bleness Hospital Athens, Ohio	Site Public Contact - (Jennifer.Sexton@ohiohealth.com)
OhioHealth Pickerington Methodist Hospital Pickerington, Ohio	Site Public Contact - (Jennifer.Sexton@ohiohealth.com)
OhioHealth Westerville Medical Campus/Westerville Cancer Center Westerville, Ohio	Site Public Contact - (Jennifer.Sexton@ohiohealth.com)
Oklahoma Cancer Specialists and Research Institute-Tulsa Tulsa, Oklahoma
Oncology Associates PC Omaha, Nebraska
Oncology Associates at Mercy Medical Center Cedar Rapids, Iowa
Oncology Hematology Associates of Saginaw Valley PC Saginaw, Michigan
OptumCare Cancer Care at Charleston Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
OptumCare Cancer Care at Fort Apache Las Vegas, Nevada	Site Public Contact - (research@sncrf.org)
OptumCare Cancer Care at Seven Hills Henderson, Nevada	Site Public Contact - (research@sncrf.org)
Orlando Health Cancer Institute Orlando, Florida	Site Public Contact - (CancerClinicalTrials@orlandohealth.com)
Ottawa Hospital and Cancer Center-General Campus Ottawa, Ontario
Overlook Hospital Summit, New Jersey
PCR Oncology Arroyo Grande, California	Site Public Contact - (research@sncrf.org)
PROncology San Juan,	Site Public Contact - (info@PRoncology.com)
Pali Momi Medical Center ‘Aiea, Hawaii
Park Nicollet Clinic - Saint Louis Park Saint Louis Park, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Parkland Health Center - Farmington Farmington, Missouri
Parkland Memorial Hospital Dallas, Texas	Site Public Contact - (canceranswerline@UTSouthwestern.edu)
Parkview Regional Medical Center Fort Wayne, Indiana
Penn State Health Saint Joseph Medical Center Reading, Pennsylvania	Site Public Contact - (dward1@pennstatehealth.psu.edu)
Penn State Milton S Hershey Medical Center Hershey, Pennsylvania	Site Public Contact - (CTO@hmc.psu.edu)
Phelps Health Delbert Day Cancer Institute Rolla, Missouri	Site Public Contact - (research@phelpshealth.org)
Phelps Memorial Hospital Center Sleepy Hollow, New York
Phoebe Putney Memorial Hospital Albany, Georgia	Site Public Contact - (ga_cares@augusta.edu)
Physicians' Clinic of Iowa PC Cedar Rapids, Iowa
Pluta Cancer Center Rochester, New York	Site Public Contact - (ctsucontact@westat.com)
Pocono Medical Center East Stroudsburg, Pennsylvania	Site Public Contact - (Morgan_M.Horton@lvhn.org)
Premier Blood and Cancer Center Dayton, Ohio
Presbyterian Kaseman Hospital Albuquerque, New Mexico
Presbyterian Rust Medical Center/Jorgensen Cancer Center Rio Rancho, New Mexico	Site Public Contact - (WBurman@phs.org)
Prisma Health Cancer Institute - Butternut Greenville, South Carolina	Site Public Contact - (Kim.Williams3@prismahealth.org)
Prisma Health Cancer Institute - Easley Easley, South Carolina	Site Public Contact - (Kim.Williams3@prismahealth.org)
Prisma Health Cancer Institute - Eastside Greenville, South Carolina	Site Public Contact - (Kim.Williams3@prismahealth.org)
Prisma Health Cancer Institute - Faris Greenville, South Carolina	Site Public Contact - (Kim.Williams3@prismahealth.org)
Prisma Health Cancer Institute - Greer Greer, South Carolina	Site Public Contact - (Kim.Williams3@prismahealth.org)
Prisma Health Cancer Institute - Seneca Seneca, South Carolina	Site Public Contact - (Kim.Williams3@prismahealth.org)
Prisma Health Cancer Institute - Spartanburg Boiling Springs, South Carolina	Site Public Contact - (Kim.Williams3@prismahealth.org)
ProHealth D N Greenwald Center Mukwonago, Wisconsin	Site Public Contact - (research.institute@phci.org)
ProHealth Oconomowoc Memorial Hospital Oconomowoc, Wisconsin
ProMedica Flower Hospital Sylvania, Ohio	Site Public Contact - (PCIOncResearch@promedica.org)
Providence Cancer Institute Clackamas Clinic Clackamas, Oregon
Providence Newberg Medical Center Newberg, Oregon	Site Public Contact - (CanRsrchStudies@providence.org)
Providence Portland Medical Center Portland, Oregon	Site Public Contact - (CanRsrchStudies@providence.org)
Providence Saint Vincent Medical Center Portland, Oregon	Site Public Contact - (CanRsrchStudies@providence.org)
Providence Willamette Falls Medical Center Oregon City, Oregon	Site Public Contact - (CanRsrchStudies@providence.org)
Queen's Cancer Cenrer - POB I Honolulu, Hawaii
Queen's Cancer Center - Kuakini Honolulu, Hawaii
Queen's Medical Center Honolulu, Hawaii
Queens Hospital Center Jamaica, New York
Reading Hospital West Reading, Pennsylvania
Regional Cancer Center-Lee Memorial Health System Fort Myers, Florida	Site Public Contact - (protocols@AllianceNCTN.org)
Regions Hospital Saint Paul, Minnesota	Site Public Contact - (mmcorc@healthpartners.com)
Renown Regional Medical Center Reno, Nevada
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Rex Hematology Oncology Associates-Garner Garner, North Carolina	Site Public Contact - (CancCtrOncologyClinicalResearch@unchealth.unc.edu)
Rhode Island Hospital Providence, Rhode Island
Riverside Methodist Hospital Columbus, Ohio	Site Public Contact - (Jennifer.Sexton@ohiohealth.com)
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Roswell Park Cancer Institute Buffalo, New York
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Rutgers Cancer Institute of New Jersey New Brunswick, New Jersey
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UM Baltimore Washington Medical Center/Tate Cancer Center Glen Burnie, Maryland
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Mirvetuximab Soravtansine With Bevacizumab Versus Bevacizumab as Maintenance in Platinum-sensitive Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer (GLORIOSA)

Contact(s):

ABBVIE CALL CENTER - abbvieclinicaltrials@abbvie.com

Principal Investigator:

System ID: NCT05445778

Show full eligibility criteria

Interventions: DRUG: Mirvetuximab soravtansine plus Bevacizumab, DRUG: Bevacizumab

Conditions: Ovarian Cancer, Peritoneal Cancer, Fallopian Tube Cancer

Keywords: Platinum-sensitive, Folate-receptor alpha expression, Antibody-drug conjugate, Cancer, Ovarian Neoplasma, Recurrent Platinum-Sensitive, High-Grade Ovarian, ADC, Adult

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Study Locations

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Location	Contacts
AUSL Piacenza-Ospedale Guglielmo da Saliceto /ID# 269468 Piacenza,
AUSL di Reggio Emilia - Arcispedale Santa Maria Nuova /ID# 269471 Reggio Emilia,
AZ Sint-Lucas /ID# 269366 Ghent, Oost-Vlaanderen
AZ-Delta /ID# 269091 Roeselare, West-Vlaanderen
Affiliated Cancer Hospital of Guangxi Medical University Nanning, Guangxi
Aichi Cancer Center /ID# 274332 Nagoya, Aichi-ken
Alessandro Manzoni Hospital /ID# 269467 Lecco,
Allegheny Health Network West Penn Hospital /ID# 269551 Pittsburgh, Pennsylvania
Arthur J. E. Child Comprehensive Cancer Centre /ID# 269388 Calgary, Alberta
Asan Medical Center /ID# 269480 Seoul, Seoul Teugbyeolsi
Asplundh Cancer Pavilion /ID# 269574 Willow Grove, Pennsylvania
Azienda Ospedaliero Universitaria Careggi /ID# 269465 Florence, Firenze
Azienda Ospedaliero Universitaria Di Parma /ID# 269466 Parma,
Azienda Ospedaliero-Universitaria Policlinico Umberto I /ID# 269470 Rome, Roma
Azienda USL Toscana Nord Ovest - Ospedale San Luca /ID# 269095 Lucca,
BC Cancer - Vancouver /ID# 269394 Vancouver, British Columbia
Ballarat Base Hospital /ID# 269364 Ballarat, Victoria
Baptist Health Lexington /ID# 269568 Lexington, Kentucky
Baptist Md Anderson Cancer Center - Jacksonville - Palm Avenue /ID# 269560 Jacksonville, Florida
Baskent Universitesi Adana Uyg. Ve Arast. Merkezi Yuregir Baskent Hastanesi /ID# 270174 Adana,
Baystate Medical Center /ID# 269544 Springfield, Massachusetts
Başkent Üniversitesi Ankara Hastanesi /ID# 269524 Ankara,
Bc Cancer Agency - Fraser Valley Centre /ID# 269398 Surrey, British Columbia
Beaumont Hospital /ID# 269452 Dublin,
Beijing Cancer Hospital Beijing,
Beneficência Portuguesa de São Paulo /ID# 269092 São Paulo, São Paulo
Bon Secours Cork Hospital /ID# 269449 Cork,
Broward General Medical Center /ID# 269577 Fort Lauderdale, Florida
CHA Bundang Medical Center /ID# 269489 Seongnam, Gyeonggido
CHU Brest /ID# 269422 Brest, Finistere
CHUM - Centre hospitalier de l'Universite de Montréal /ID# 269387 Montreal, Quebec
CIUSSS Estrie - Sherbrooke University Hospital Center /ID# 269393 Sherbrooke, Quebec
CLINICA UNIVERSIDAD DE NAVARRA-Madrid /ID# 269405 Madrid,
Cabrini Hospital Malvern /ID# 269359 Malvern, Victoria
Cancer Hospital Affliated to Xinjiang Medical University Ürümqi, Xinjiang
Capital Medical University (Cmu) Beijing, Beijing Municipality
Cardinal Santos Medical Center /ID# 269100 San Juan City, National Capital Region
Casa di Cura San Pio X /ID# 277973 Milan, Milano
Catarina Pesquisa Clinica /ID# 269379 Itajaí, Santa Catarina
Centre Leon Berard /ID# 269418 Lyon, Rhone
Cheltenham General Hospital /ID# 269427 Cheltenham, Gloucestershire
Chiba University Hospital /ID# 274371 Chiba, Chiba
Chu Dijon /Id# 269417 Dijon, Bourgogne-Franche-Comté
City of Hope - Orange County Lennar Foundation Cancer Center /ID# 269573 Irvine, California
Clinica Universidad de Navarra - Pamplona /ID# 269410 Pamplona, Navarre
Cliniques Universitaires UCL Saint-Luc /ID# 269368 Brussels, Brussels Capital
Compass Oncology - Rose Quarter /ID# 270131 Portland, Oregon
Complejo Hospitalario Universitario A Coruña /ID# 269414 A Coruña, A Coruna
Complex Oncology Center - Shumen /ID# 269372 Shumen,
Comprehensive Cancer Center /ID# 269373 Vratsa,
Corewell Health /ID# 269562 Grand Rapids, Michigan
Cork University Hospital /ID# 269451 Cork,
Cross Cancer Institute /ID# 269392 Edmonton, Alberta
Dartmouth-Hitchcock Medical Center /ID# 269576 Lebanon, New Hampshire
Duke Cancer Institute /ID# 269557 Durham, North Carolina
East Avenue Medical Center /ID# 269099 Quezon City, National Capital Region
Edith Wolfson Medical Center /ID# 269461 Holon, Central District
Ente Ospedaliero Ospedali Galliera /ID# 269472 Genoa, Genova
Epworth Hospital /ID# 269363 Richmond, Victoria
Fakultní Nemocnice Brno - Jihlavská /ID# 269401 Brno, Brno-mesto
Fakultní nemocnice Ostrava /ID# 269403 Ostrava, Ostrava-mesto
Fondazione IRCCS Policlinico San Matteo /ID# 269463 Pavia,
Fondazione Policlinico Universitario Agostino Gemelli IRCCS-Università Cattolica /ID# 269096 Rome, Roma
Fudan University Cancer Hospital Shanghai, Shanghai Municipality
Fujian Province Cancer Hospital Fuzhou, Fujian
GBMC Cancer Center /ID# 269561 Towson, Maryland
Gangnam Severance Hospital /ID# 269484 Seoul, Seoul Teugbyeolsi
General Hospital of Athens Alexandra /ID# 269444 Athens,
General University Hospital in Prague, Charles University /ID# 269402 Prague, Ceske Budejovice
Gold Coast University Hospital /ID# 269365 Southport, Queensland
Grand Hôpital De Charleroi - Notre Dame /ID# 269367 Charleroi, Hainaut
Guy's Hospital /ID# 269426 London, Greater London
Hacettepe University Faculty of Medicine /ID# 269521 Ankara,
Hadassah Medical Center-Hebrew University /ID# 269458 Jerusalem,
Harbin Medical University Cancer Hospital Harbin, Heilongjiang
Henan Cancer Hospital Zhengzhou, Henan
Hokkaido University Hospital /ID# 274331 Sapporo, Hokkaido
Holy Name Medical Center /ID# 269543 Teaneck, New Jersey
Honorhealth Virginia G. Piper Cancer Care Network - Biltmore /ID# 269987 Phoenix, Arizona
Hospital Clinic de Barcelona /ID# 269408 Barcelona,
Hospital Clínico Universitario de Valencia /ID# 269412 Valencia,
Hospital Italiano de Buenos Aires /ID# 269356 Buenos Aires,
Hospital Italiano de Córdoba (Sociedad de Beneficencia Hospital Italiano) /ID# 269090 Córdoba,
Hospital Nove De Julho /ID# 269375 São Paulo, São Paulo
Hospital Santa Izabel /ID# 269384 Salvador, Estado de Bahia
Hospital Universitari De Girona Doctor Josep Trueta /ID# 269411 Girona,
Hospital Universitari Vall d'Hebron /ID# 269406 Barcelona,
Hospital Universitario La Paz /ID# 269407 Madrid,
Hospital Universitario Reina Sofia /ID# 270296 Córdoba, Cordoba
Hospital Universitario Virgen de la Victoria /ID# 269413 Málaga, Malaga
Hubei Cancer Hospital Wuhan,
Hunan Province Cancer Hospital Changsha, Hunan
Hygeia Hospital /ID# 270132 Athens,
Hyogo Cancer Center /ID# 274323 Akashi-shi, Hyōgo
Hôpital La Timone /ID# 269421 Marseille, Bouches-du-Rhone
IASO Hospital /ID# 269443 Marousi,
IRCCS AOU di Bologna Policlinico Sant Orsola Malpighi /ID# 269476 Bologna,
IRCCS Istituto Clinico Humanitas /ID# 269473 Rozzano, Lombardy
IRCCS Ospedale San Raffaele /ID# 269475 Milan, Milano
Icahn School of Medicine at Mount Sinai /ID# 269529 New York, New York
Imelda Ziekenhuis /ID# 269369 Bonheiden, Antwerpen
Indiana University Melvin and Bren Simon Comprehensive Cancer Center /ID# 269110 Indianapolis, Indiana
Institut Català d'Oncologia (ICO) - L'Hospitalet /ID# 269409 L'Hospitalet de Llobregat, Barcelona
Institut Curie /ID# 269420 Paris, Île-de-France Region
Institut de cancérologie Strasbourg Europe (ICANS) /ID# 269419 Strasbourg, Bas-Rhin
Isis Centro Especializado De Luce /ID# 269353 Santa Fe,
Istituto Nazionale Dei Tumori /ID# 269477 Milan, Milano
Istituto Nazionale Tumori Irccs Fondazione G. Pascale /ID# 269097 Naples, Napoli
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST - IRCCS /ID# 269474 Meldola, Reggio Emilia
Iwate Medical University Hospital - Yahabacho /ID# 274635 Yahaba, Iwate
Jagiellonskie Centrum Innowacji Sp. z o.o. /ID# 269497 Krakow, Lesser Poland Voivodeship
Jichi Medical University Hospital /ID# 274634 Shimotsuke-shi, Tochigi
John Muir Health - Walnut Creek Medical Center /ID# 269575 Walnut Creek, California
John Theurer Cancer Center /ID# 269109 Hackensack, New Jersey
Johns Hopkins Hospital /ID# 269579 Baltimore, Maryland
Juravinski Cancer Centre - Hamilton Health Sciences /ID# 269396 Hamilton, Ontario
Kagoshima University Hospital /ID# 276081 Kagoshima, Kagoshima-ken
Kaiser Permanente - San Diego Medical Center /ID# 269540 San Diego, California
Kaiser Permanente - San Marcos Medical Offices /ID# 269542 San Marcos, California
Kaiser Permanente Zion Medical Center /ID# 269537 San Diego, California
Kaplan Medical Center /ID# 269457 Rehovot, Central District
Keimyung University Dongsan Hospital /ID# 269488 Daegu, Gyeongsangbuk-do
Keio University Hospital /ID# 276159 Shinjuku-ku, Tokyo
Kettering Medical Center /ID# 269585 Kettering, Ohio
Kingston General Hospital /ID# 269397 Kingston, Ontario
Klinikum Dortmund Klinikzentrum Mitte /ID# 269441 Dortmund, North Rhine-Westphalia
Klinikum Esslingen /ID# 269435 Esslingen am Neckar, Baden-Wurttemberg
Korea University Anam Hospital /ID# 269486 Seoul, Seoul Teugbyeolsi
Korea University Guro Hospital /ID# 269490 Seoul, Seoul Teugbyeolsi
Krankenhaus Jerusalem /ID# 269430 Hamburg,
Kurume University Hospital /ID# 274337 Kurume-shi, Fukuoka
Liaoning Cancer Hospital & Institute Shenyang, Liaoning
Linyi Cancer Hospital Linyi, Shandong
Louisiana State University Health Sciences Center - New Orleans /ID# 269559 New Orleans, Louisiana
Maine Medical Center - Scarborough Campus /ID# 269555 Scarborough, Maine
Mazowiecki Szpital Wojewodzki im. Sw. Jana Pawla II w Siedlcach Sp. z o.o. /ID# 269500 Siedlce, Masovian Voivodeship
McGill University Health Centre - Glen Site /ID# 269389 Montreal, Quebec
Meir Medical Center /ID# 269454 Kfar Saba, Central District
Minnesota Oncology - Coon Rapids Clinic /ID# 269550 Coon Rapids, Minnesota
Monash Health - Monash Medical Centre /ID# 269360 Clayton, Victoria
Moores Cancer Center at UC San Diego /ID# 269564 La Jolla, California
Mount Sinai Medical Center /ID# 269582 Miami, Florida
Mount Vernon Hospital /ID# 269423 Northwood, Greater London
NYU Laura and Isaac Perlmutter Cancer Center /ID# 269556 New York, New York
National Cancer Center /ID# 269481 Goyang-si, Gyeonggido
National Cancer Center Hospital /ID# 274321 Chuo-Ku, Tokyo
National Hospital Organization Shikoku Cancer Center /ID# 276078 Matsuyama, Ehime
Nebraska Methodist Hospital /ID# 269580 Omaha, Nebraska
Nemocnice Novy Jicin /ID# 269400 Nový Jičín, Novy Jicin
New Hospital of Prato - S. Stefano /ID# 269464 Prato,
New York Oncology Hematology - Albany Cancer Center /ID# 269565 Albany, New York
Niigata University Medical & Dental Hospital /ID# 274329 Niigata, Niigata
Northside Hospital /ID# 269660 Atlanta, Georgia
Northwell Health Center for Advanced Medicine /ID# 269108 Lake Success, New York
Ochsner Medical Center - Jefferson Highway /ID# 269530 New Orleans, Louisiana
Okayama University Hospital /ID# 274324 Okayama, Okayama-ken
Oklahoma Cancer Specialists and Research Institute /ID# 269527 Tulsa, Oklahoma
Olive View-Ucla Medical Center /ID# 269584 Sylmar, California
Onkologische Schwerpunktpraxis Bielefeld /ID# 269440 Bielefeld, North Rhine-Westphalia
Oregon Health and Science University /ID# 269581 Portland, Oregon
Osaka Medical And Pharmaceutical University Hospital /ID# 276079 Takatsuki, Osaka
Ospedale Cannizzaro /ID# 269478 Catania,
Ospedale San Martino /ID# 269469 Genoa, Genova
Ospedale di Mirano - Azienda ULSS 3 /ID# 269462 Mirano, Venezia
Ou Health - Stephenson Cancer Center /ID# 269525 Oklahoma City, Oklahoma
Peter MacCallum Cancer Centre /ID# 269361 Melbourne, Victoria
Princess Margaret Cancer Centre /ID# 269390 Toronto, Ontario
Qilu Hospital of Shandong University Jinan, Shandong
Rabin Medical Center /ID# 269456 Petah Tikva, Central District
Regional Cancer Center /ID# 269558 Fort Myers, Florida
Rush University Medical Center /ID# 269583 Chicago, Illinois
Saitama Medical University International Medical Center /ID# 274953 Hidaka, Saitama
Samsung Medical Center /ID# 269487 Seoul, Seoul Teugbyeolsi
Sanatorio De La Mujer /ID# 269352 Rosario, Santa Fe Province
Sanford Cancer Center /ID# 269535 Sioux Falls, South Dakota
Sapporo Medical University Hospital /ID# 274330 Sapporo, Hokkaido
Sarasota Memorial Hospital /ID# 269526 Sarasota, Florida
Seoul National University Bundang Hospital /ID# 269482 Seongnam-si, Gyeonggido
Seoul National University Hospital /ID# 269479 Seoul, Seoul Teugbyeolsi
Shaare Zedek Medical Center /ID# 269459 Jerusalem,
Shandong Cancer Hospital Jinan, Shandong
Shanxi Cancer Hospital Taiyuan, Shanxi
Shizuoka Cancer Center /ID# 274325 Sunto-gun, Shizuoka
Sinai Hospital Of Baltimore /ID# 269567 Manchester, Maryland
Singleton Hospital /ID# 269424 Swansea,
Sligo General Hospital /ID# 269448 Sligo,
St James Hospital /ID# 269446 Dublin, Dublin
St. John Of God Subiaco Hospital /ID# 269358 Subiaco, Western Australia
St. Luke's Hospital S.A. /ID# 269445 Panórama, Thessaloniki
St. Vincent Indianapolis Hospital /ID# 269107 Indianapolis, Indiana
Stanford Women'S Cancer Center /ID# 269552 Palo Alto, California
Sun Yat-Sen University (Sysu) - Sun Yat-Sen Memorial Hospital Guangzhou, Guangdong
Swedish Cancer Institute /ID# 269538 Seattle, Washington
Szpitale Pomorskie Sp. z o.o. /ID# 269495 Gdynia, Pomeranian Voivodeship
Tel Aviv Sourasky Medical Center /ID# 269455 Tel Aviv, Tel Aviv
Texas Oncology - Austin Central /ID# 269531 Austin, Texas
Texas Oncology - Bedford /ID# 269571 Bedford, Texas
Texas Oncology - Fort Worth Cancer Center /ID# 269532 Fort Worth, Texas
Texas Oncology - Methodist Dallas Cancer Center /ID# 269554 Dallas, Texas
Texas Oncology - San Antonio Medical Center - Research Drive /ID# 269549 San Antonio, Texas
The Affiliated Women's Hospital Of Zhejiang University Hangzhou, Zhejiang
The Cancer Institute Hospital Of JFCR /ID# 274326 Koto-ku, Tokyo
The Catholic University of Korea, Seoul St. Marys Hospital /ID# 269485 Seoul, Seoul Teugbyeolsi
The Center Of Hope /ID# 269528 Reno, Nevada
The Chaim Sheba Medical Center /ID# 269094 Ramat Gan, Tel Aviv
The Christie /ID# 269428 Manchester,
The First Affiliated Hospital of Xi'An Jiaotong University Xi’an, Shanxi
The First Affiliated Hospital, Sun-Yat Sen University Guangzhou, Guangdong
The First Bethune Hospital of Jilin University Changchun,
The Jikei University Kashiwa Hospital /ID# 274334 Kashiwa, Chiba
The Jikei University School of Medicine /ID# 276160 Tokyo,
The Lady Davis Carmel Medical Center /ID# 269453 Haifa,
The Medical City /ID# 269493 Pasig, National Capital Region
The Ohio State University Comprehensive Cancer Center /ID# 269105 Columbus, Ohio
The Ottawa Hospital - General Campus /ID# 269391 Ottawa, Ontario
The Royal Marsden - Chelsea /ID# 269102 London, Greater London
The Royal Marsden - Sutton /ID# 269103 Sutton, Surrey
The Second Affiliated Hospital of Zhengzhou University Zhengzhou, Henan
The University of Kansas Cancer Center - Westwood /ID# 269106 Westwood, Kansas
The Valley Hospital /ID# 269548 Paramus, New Jersey
The first affiliated hospital of bengbu medical college Bengbu, Anhui
Tianjin Cancer Hospital Tianjin,
Tohoku University Hospital /ID# 274327 Sendai, Miyagi
Tokai University Hospital /ID# 274336 Isehara, Kanagawa
Tufts Medical Center /ID# 269547 Boston, Massachusetts
UCL Namur University Hospital, Site Sainte-Elisabeth /ID# 269371 Namur,
US Oncology Research Investigational Products Center /ID# 278746 Irving, Texas
Universitaetsklinikum Bonn /ID# 269434 Bonn, North Rhine-Westphalia
Universitaetsklinikum Carl Gustav Carus Dresden /ID# 269433 Dresden, Saxony
Universitaetsklinikum Erlangen /ID# 269439 Erlangen, Bavaria
Universitaetsklinikum Hamburg-Eppendorf /ID# 269429 Hamburg,
Universitaetsklinikum Heidelberg /ID# 269438 Heidelberg, Baden-Wurttemberg
Universitaetsmedizin Mainz /ID# 269442 Mainz, Rhineland-Palatinate
Universitair Ziekenhuis Leuven /ID# 269370 Leuven, Vlaams-Brabant
Universite de Montreal - Hopital Maisonneuve-Rosemont /ID# 269395 Montreal, Quebec
University Hospital Galway /ID# 269447 Galway,
University Hospital Southampton /ID# 269425 Southampton, Hampshire
University Of California Irvine Medical Center /ID# 269572 Orange, California
University Of Pittsburgh Medical Center Magee - Womens Hospital /ID# 269659 Pittsburgh, Pennsylvania
University of Chicago Medical Center /ID# 269546 Chicago, Illinois
University of Cincinnati /ID# 269578 Cincinnati, Ohio
University of Iowa /ID# 269566 Iowa City, Iowa
University of Kentucky Chandler Medical Center /ID# 269536 Lexington, Kentucky
University of North Carolina at Chapel Hill /ID# 269563 Chapel Hill, North Carolina
University of Virginia Health System /ID# 269545 Charlottesville, Virginia
Universitätsklinikum Gießen /ID# 269432 Giessen,
Usa Mitchell Cancer Institute /ID# 269661 Mobile, Alabama
Vcu Health Adult Outpatient Pavillion /ID# 269570 Richmond, Virginia
Virginia Oncology Associates - Norfolk (Lake Wright) /ID# 269533 Norfolk, Virginia
Waterford Regional Hospital /ID# 269450 Waterford,
West Cancer Center and Research Institute - Germantown /ID# 269569 Germantown, Tennessee
West China Second University Hospital, Sichuan University Chengdu, Sichuan
Westmead Hospital /ID# 269362 Westmead, New South Wales
Wielkopolskie Centrum Onkologii /ID# 269494 Poznan, Greater Poland Voivodeship
Willamette Valley Cancer Institute and Research Center /ID# 269988 Eugene, Oregon
Women'S Cancer Care Associates /ID# 269553 Albany, New York
Yonsei University Health System Severance Hospital /ID# 269483 Seoul, Seoul Teugbyeolsi
Yunnan Province Cancer Hospital Kunming, Yunnan
ZIV Medical Center /ID# 269460 Safed,
Zhejiang Cancer Hospital Zhejiang,

A Phase 1 Clinical Study of NXP800 in Subjects with Advanced Cancers and Expansion in Subjects with Ovarian Cancer

Contact(s):

Diane Marsolini - dmarsolini@nuvectis.com

Principal Investigator:

System ID: NCT05226507

Show full eligibility criteria

Part A

Inclusion Criteria:

* Provide written informed consent. * 18 years old or older. * Life expectancy of at least 12 weeks. * Histologically- or cytologically-confirmed, advanced, metastatic, and/or progressive solid tumors for whom there is no authorized or effective therapy available, or for whom such therapies are considered inappropriate by the Investigator (in Part B, subjects with specific cancer types will be enrolled; Specific criteria will be introduced in a protocol amendment). * Measurable disease according to Response Evaluation Criteria in Solid Tumors (RECIST) Version 1.1. * Eastern Cooperative Oncology Group (ECOG) performance status of ≤ 2. Part A

Exclusion Criteria:

* Radiotherapy (except for palliative reasons), endocrine therapy, chemotherapy, or investigational agent within 28 days, (42 days for nitrosoureas, mitomycin-C) of first dose of NXP800. Subjects can continue to receive bisphosphonates due to metastatic bone disease or GnRH agonists if they have prostate cancer. * Ongoing toxic manifestations of previous treatments \> Grade 2. * Subjects with treated brain metastases are eligible if there is no evidence of progression for at least 28 days after central nervous system (CNS) directed treatment, as ascertained by clinical examination and brain imaging (magnetic resonance imaging \[MRI\] or computed tomography \[CT\] scan) during the Screening period. * Female subjects who can become pregnant (or are already pregnant or lactating). * Male subjects with partners of childbearing potential (unless they agree to take measures not to father children by using a barrier method of contraception (condom plus spermicide) or to sexual abstinence). Part B

Inclusion Criteria:

* Provide written informed consent. * 18 years old or older. * Subjects with the following ARID1a mutated, ovarian/fallopian tube/primary peritoneal cancer histologies (ARID1a mutation status determined by a DNA-based Next Generation Sequencing test): * Clear cell ovarian carcinoma (≥ 50% clear cell carcinoma with no serous differentiation) * Endometrioid ovarian carcinoma * Subjects must have disease progression within 6 months (182 days) from completion of platinum-based therapy (6 months should be calculated from the date of the last administered dose of platinum therapy to the date of radiographic imaging showing progression) * Measurable disease according to Response Evaluation Criteria in Solid Tumors (RECIST) Version 1.1. * Subjects with a BRCA mutation must have received prior treatment with a PARP inhibitor. * Subjects must have received at least 1 but not more than 3 prior systemic lines of anticancer therapy, including at least 1 line of therapy containing bevacizumab. * Adjuvant + neoadjuvant are considered one line of therapy * Maintenance therapy (i.e., bevacizumab, PARP inhibitors) will be considered as part of the preceeding line of therapy and are not counted independently. * Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1. * Subjects must have a sufficient archival Formalin-Fixed Paraffin-Embedded (FFPE) tissue specimen, or be willing to consent to a fresh tissue biopsy during the study. Part B

Exclusion Criteria:

* Subjects with disease that did not respond to, or has progressed during or within 4 weeks of the last dose of first-line platinum containing chemotherapy. * Radiotherapy (except for palliative reasons), endocrine therapy, chemotherapy, or investigational agent within 28 days, (42 days for nitrosoureas, mitomycin-C) of first dose of NXP800. * Ongoing toxic manifestations of previous treatments \> Grade 2, with the exception of alopecia. * Subjects with treated brain metastases are eligible if there is no evidence of progression for at least 12 weeks while off corticosteroids after central nervous system (CNS) directed treatment, as ascertained by clinical examination and brain imaging (magnetic resonance imaging \[MRI\] or computed tomography \[CT\] scan) during the Screening period. * Female subjects who can become pregnant (or are already pregnant or lactating).

Interventions: DRUG: NXP800

Conditions: Advanced Solid Tumor, Ovarian Cancer, Ovarian Clear Cell Carcinoma, Ovarian Clear Cell Tumor, Ovarian Clear Cell Adenocarcinoma, Ovarian Endometrioid Adenocarcinoma, Ovarian Endometrioid Tumor, ARID1A Gene Mutation

Keywords: Solid Tumor, Carcinoma, Neoplasms, Adenocarcinoma, ARID1a

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Study Locations

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Location	Contacts
Addenbrookes Hospital Cambridge,
Florida Cancer Specialists Research East West Palm Beach, Florida	- (clinicaltrials@flcancer.com)
Florida Cancer Specialists Research North St. Petersburg, Florida	- (clinicaltrials@flcancer.com)
Florida Cancer Specialists South Fort Myers, Florida	- (clinicaltrials@flcancer.com)
Honor Health Scottsdale, Arizona
Mount Sinai Comprehensive Cancer Center Miami Beach, Florida
OU Health Stephenson Cancer Center Oklahoma City, Oklahoma
Oklahoma Cancer Specialists and Research Institute Tulsa, Oklahoma	Melissa Barnes - (melissa.barnes@oscri.org)
Oncology Associates of Oregon Eugene, Oregon
Royal Marsden Hospital Chelsea, England
Rutgers Cancer Institute of New Jersey New Brunswick, New Jersey	Kassie DiOrio - (kassie.diorio@rutgers.edu)
Sidney Kimmel Cancer Center, Asplundh Cancer Pavilion Willow Grove, Pennsylvania	Ashley Douglas, RN, BSN, OCN - (ashley.douglas.2@jefferson.edu)
Texas Oncology Dallas, Texas
The Beatson West of Scotland Cancer Centre Glasgow,	Ruth Orr - (ruth.orr@ggc.scot.nhs.uk)
The Ohio State University Comprehensive Cancer Center Columbus, Ohio
The University of Texas MD Anderson Cancer Center Houston, Texas
UC San Diego Health - Moores Cancer Center San Diego, California	Alexandrea Cronin - (aocronin@health.ucsd.edu)
University of Colorado Cancer Center Aurora, Colorado
University of Iowa Iowa City, Iowa	David Bender, MD - (david-bender@uiowa.edu)
University of Virginia Health System Charlottesville, Virginia
VCU Massey Comprehensive Cancer Center Richmond, Virginia
Women's Cancer Care Associates Albany, New York
Yale Gynecologic Oncology New Haven, Connecticut

Immune Registry for BK in Kidney Transplant Recipients

Contact(s):

Ambreen Azhar - ambreen.azhar@vcuhealth.org

Principal Investigator:

System ID: NCT06538961

Show full eligibility criteria

Interventions: OTHER: Blood samples: Main Study group, OTHER: Data Collection, OTHER: Urine Sample- Main Study group, OTHER: Urine sample- Sub-study group, OTHER: Blood sample: Sub-study group

Conditions: BK Virus Infection, Kidney Transplant, Complications

Keywords: Immune Registry, BK in Kidney Transplant Recipients

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Location	Contacts
Virginia Commonwealth University Richmond, Virginia	Ambreen Azhar - (ambreen.azhar@vcuhealth.org) Gelila Abebe - (gelila.abebe@vcuhealth.org)

Anti-Inflammatory Lifestyle Intervention for Emerging Adult Cancer Survivors (HEAL)

Contact(s):

Tyler Phillips - phillipst5@vcu.edu

Principal Investigator:

System ID: NCT06442397

Show full eligibility criteria

Interventions: BEHAVIORAL: Anti-Inflammatory Lifestyle Intervention

Conditions: Survivorship

Keywords: Adult Cancer Survivors, Anti-Inflammatory Lifestyle for Cancer Survivors

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Location	Contacts
Virginia Commonwealth University, School of Medicine Richmond, Virginia	Tyler Phillips - (phillipst5@vcu.edu)

A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM) (DISCOVER-HCM)

Contact(s):

BMS Study Connect Contact Center www.BMSStudyConnect.com - Clinical.Trials@bms.com

Principal Investigator:

System ID: NCT05489705

Show full eligibility criteria

Inclusion Criteria * ≥ 18 years of age at the time of informed consent. * Willing and able to provide written informed consent form (ICF) and any required privacy authorization prior to the initiation of study procedures (or in those situations where consent cannot be given by participants, consent provided by their legally acceptable representatives) United States Sub-Study * Diagnosis of obstructive HCM consistent with 2020 American Heart Association/American College of Cardiology (AHA/ACC) guidelines. * Obstructive HCM is defined clinically by the presence of increased LV wall thickness ≥ 15 mm (or ≥ 13 mm with positive family history of HCM) in a nondilated ventricular chamber that is not solely explained by abnormal loading conditions (eg, another cardiac or systemic disease) and peak LVOT gradient of ≥ 30 mmHg at rest or with provocation. * Has documented LVEF of ≥ 55% recorded by echocardiography within the last 6 months. * Symptoms consistent with NYHA functional class II-IV. * Receiving beta blocker (BB)s, non-dihydropyridine calcium. channel blockers (nonDHP CCBs), disopyramide, and/or mavacamten (once available) as part of routine clinical care; or currently receiving no treatment due to intolerance or failure of prior treatment (eg, BBs, non-DHP CCBs, or disopyramide) for obstructive HCM. European Sub-study * Diagnosis of obstructive HCM consistent with the most recent European Society of Cardiology (ESC) and American Heart Association/American College of Cardiology (AHA/ACC) guidelines * Documented LVEF of ≥55% recorded by TTE * Documented symptoms consistent with NYHA functional class II-III at enrollment or within 6 months prior to enrollment (if not available at enrollment). * As part of routine clinical care for obstructive HCM: receiving BBs, non-DHP CCBs, disopyramide; initiating mavacamten at enrollment; or currently receiving no treatment due to intolerance or failure of prior treatment (e.g., BBs, non-DHP CCBs, or disopyramide). Exclusion Criteria * Known phenocopy disease (e.g., Fabry disease, amyloidosis) or LV hypertrophy associated with hypertension. * Documentation of any fixed obstruction of the outflow tract such as aortic valve stenosis or replacement. * Prior treatment of obstructive HCM with invasive septal reduction (surgical myectomy or percutaneous alcohol septal ablation \[ASA\]) within 6 months prior to enrollment; participants with an unsuccessful myectomy or percutaneous ASA performed \> 6 months prior to enrollment may be enrolled. * Naïve to treatment for obstructive HCM (ie, never treated with BBs, nonDHP CCBs, or disopyramide). United States Sub-Study * Receiving an investigational therapeutic agent for obstructive HCM (eg, myosin-inhibitors other than mavacamten) in an interventional clinical trial at participant enrollment. * Previously or currently enrolled in a long-term safety extension study of mavacamten (eg, EXPLORER-HCM \[ClinicalTrials.gov, NCT03470545\], MAVA-LTE \[NCT03723655\], PIONEER-OLE \[NCT03496168\], VALORHCM \[NCT04349072\], or MAVERICK \[NCT03442764\]) European Sub-study * Receiving an investigational therapeutic agent or any cardiac myosin inhibitor and/or modulators for obstructive HCM at patient enrolment * Previously or currently enrolled in other HCM registry studies (e.g., TORCH, REMY, EU-PASS) * Previously or currently enrolled in a study of mavacamten (e.g., EXPLORER-HCM \[ClinicalTrials.gov, NCT03470545\], MAVA-LTE \[NCT03723655\], PIONEER-OLE \[NCT03496168\], VALOR-HCM \[NCT04349072\], MAVERICK \[NCT03442764\], or MEMENTO \[NCT2264899\]) * Previously treated with mavacamten

Interventions: DRUG: Mavacamten, DRUG: Non-mavacamten symptomatic oHCM therapy

Conditions: Obstructive Hypertrophic Cardiomyopathy

Keywords: Obstructive hypertrophic cardiomyopathy, Obstructive HCM (oHCM), Mavacamten, Heart failure, oHCM

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Location	Contacts
AHN Allegheny General Hospital Pittsburgh, Pennsylvania
Alaska Heart Institute Anchorage, Alaska
BI Research Center Houston, Texas
Bassett Medical Center Cooperstown, New York
Baylor Scott & White Medical Centre - Temple Temple, Texas
Baylor Scott & White Research Institute Dallas, Texas
Baylor Scott & White The Heart Hospital Plano Plano, Texas
CHI Health Reseach Center Omaha, Nebraska
CHU Amiens-Picardie Amiens, Somme
CHU De Poitiers - Hopital De La Miletrie Poitiers, Vienne
CHU Nantes Hopital Nord Laennec Saint-Herblain, Loire Atlantique
Cardiology Associates Research, LLC Tupelo, Mississippi
Carilion Clinic; Virginia Tech-Carilion School of Medicine Roanoke, Virginia
Centre Hospitalier Haguenau Haguenau, Bas Rhin
Christ Hospital Health Network Cincinnati, Ohio
Cleveland Clinic Cleveland, Ohio
Duke University Health System Durham, North Carolina
Focus Clinical Research Charlotte, North Carolina
Franciscan Physician Network-Indiana Heart Physicians Indianapolis, Indiana
Geisinger Health System Wilkes-Barre, Pennsylvania
Hackensack University Medical Center Hackensack, New Jersey
Hartford Healthcare Hartford, Connecticut
Harvard (Massachusetts General Hospital) Boston, Massachusetts
Harvard Medical School - Brigham and Women's Hospital (BWH) Boston, Massachusetts
Henry Ford Health System Detroit, Michigan
Hospital Clinico San Carlos Madrid,
Hospital Clinico Universitario Virgen de la Victoria Málaga,
Hospital Fundacion Son Llatzer Palma de Mallorca, Balearic Islands
Hospital Universitario Central de Asturias Oviedo, Principality of Asturias
Hospital Universitario Puerta de Hierro Majadahonda Majadahonda,
Hospital Universitario Virgen de la Arrixaca El Palmar,
Hospital Universitario de Burgos Burgos,
Hôpital Saint Vincent-de-Paul Lille, Nord
Hôpital Sainte Musse Toulon, Var
Immanuel Klinikum Bernau Bernau, State of Berlin
Imperial College Healthcare NHS Trust London, Greater London
Indiana. University Indianapolis, Indiana
KH St.Josef Braunau am Inn Braunau am Inn,
Kardiologische und angiologische Praxen im Spreebogen Berlin,
Keck School of Medicine of USC-Usc Los Angeles, California
Kepler Universitätsklinikum Linz Linz,
LKH-Univ. Klinikum Graz Graz,
Lancaster General Hospital Lancaster, Pennsylvania
Leeds General Infirmary Leeds,
Liverpool Heart and Chest Hospital Liverpool, Merseyside
Local Institution - 0083 Nice, Alpes-Maritimes
Local Institution - 0084 Strasbourg, Alsace
Local Institution - 0085 Sankt Pölten,
Local Institution - 0088 Innsbruck,
Local Institution - 0101 Erlangen, Bavaria
Local Institution - 0102 Madrid,
Local Institution - 0113 Buenos Aires, Buenos Aires F.D.
Local Institution - 0117 Seongnam, Kyǒnggi-do
Medical College of Wisconsin, Inc (PI Address) Milwaukee, Wisconsin
Medstar Health Research Institute Baltimore, Maryland
Medstar Washington Hospital Center Washington D.C., District of Columbia
Minneapolis Heart Institute Foundation Minneapolis, Minnesota
Morristown Medical Center Morristown, New Jersey
Mount Sinai Hospital New York, New York
Mount Sinai West New York, New York
North Texas Cardiology Center Dallas, Texas
Northwell Health New Hyde Park, New York
Ostalb-Klinikum Aalen Aalen, Baden-Wurttemberg
Pima Heart and Vascular Tucson, Arizona
Praxisklinik Herz Und Gefasse-Klinikum Weisser Hirsch Dresden, Saxony
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Research & Cardiovascular Corp Ponce,
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St. Luke's University Health Network Easton, Pennsylvania
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UAMS Little Rock, Arkansas
UC Denver, AMC Aurora, Colorado
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University of Chicago Dept of Medicine Chicago, Illinois
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WVU Hospitals Morgantown, West Virginia
Washington University St Louis, Missouri

The Impact of Chronic E-Cigarette Usage on Microvascular Health

Contact(s):

Paula Rodriguez Miguelez - prodriguezmig@vcu.edu

Principal Investigator:

System ID: NCT06860698

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Interventions: OTHER: E-cig use

Conditions: E-Cig Use

Keywords: Microvascular Health

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Location	Contacts
Virginia Commonwealth University Richmond, Virginia	Paula Rodriguez Miguelez - (prodriguezmig@vcu.edu)

ASHBY: Accelerated Super-Hypofractionated Breast Brachytherapy (ASHBY)

Contact(s):

Massey IIT Research Operations - masseyepd@vcu.edu

Principal Investigator:

System ID: NCT06185205

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Inclusion Criteria:

* Female * New diagnosis of ductal carcinoma in situ (DCIS) and/or invasive breast carcinoma per histologic evaluation * Age 45-79 at diagnosis * Previous lumpectomy with surgical margins histologically free of invasive tumor and DCIS as determined by the pathologist. * T stage of Tis, T1, or T2. * T2 tumors must be ≤3 cm in maximum diameter * If the tumor is human epidermal growth factor receptor 2 (HER2)-positive, the patient must receive HER2-directed therapy. * For patients with invasive breast cancer, an axillary staging procedure must be performed (either sentinel node biopsy alone or axillary dissection \[with a minimum of 6 axillary nodes removed\]) and the axillary node\[s\] must be pathologically negative. * Note: N0(i+) is not an exclusion criterion. * Note: Patients meeting all of the following criteria are not required to undergo the axillary staging procedure: * ≥70 years of age * estrogen receptor, Her2 = human epidermal growth factor receptor 2, PR = progesterone receptor negative (ER+PR+HER2-) * G1-2 * Tumor ≤2 cm in size * Agrees to comply with aromatase inhibitor recommendation * Ability to understand and the willingness to sign a written informed consent document in English

Exclusion Criteria:

* Pregnant or breastfeeding * Active collagen-vascular disease * Paget's disease of the breast * History of DCIS or invasive breast cancer prior to the current diagnosis * Prior breast or thoracic radiation therapy (RT) for any condition * Multicentric carcinoma (DCIS or invasive) * Synchronous bilateral invasive or non-invasive breast cancer * Surgical margins that cannot be microscopically assessed or that are positive * Excision cavity that cannot be clearly delineated per the treating investigator * Any of the dosimetric treatment criteria defined in Section 6.1 have not been met. Patients who become ineligible due to inability to meet dosimetric criteria should not receive treatment as - defined in this protocol and will come off the study. Any subsequent adjuvant radiation will be delivered at the discretion of the treating physician * Medical, psychological, or social condition that, in the opinion of the investigator, may increase the patient's risk or limit the patient's adherence with study requirements

Interventions: DRUG: Accelerated partial breast irradiation

Conditions: Breast Cancer

Keywords: Breast Cancer, Ductal Carcinoma in situ (DCIS), Irradiation

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Location	Contacts
Virginia Commonwealth University Richmond, Virginia	Massey CTO Breast Team - (masseyctbrst@vcu.edu)

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