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Search Results Within Category "Pain, Physical Rehabilitation, and Palliative Care"
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2 Study Matches
Peer Support for Adolescents and Emerging Adults With Sickle Cell Pain (PRESENCE)
Steffi Siebert, MPH - presencestudy@pitt.edu
NCT06374238
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Inclusion Criteria:
• Aged 16 to 39 years of age at time of enrollment
• Sickle Cell Disease diagnosis of any genotype based on referral or documentation
• Reports chronic pain (≥4 days/week for past 3 months or more) OR A) Being prescribed pain medication to be taken (≥4 days/week for past 3 months or more) OR B) Taking pain medication (≥4 days/week for past 3 months or more) OR C) Receiving non-pharmaceutical pain treatment (≥4 days/week for past 3 months or more)
• Access to an iOS or Android mobile device with internet access
Exclusion Criteria:
• Unable to speak or read English
• Prior hematopoietic stem cell transplant for sickle cell disease
• Not living in the United States throughout enrollment and duration of the study period
BEHAVIORAL: CBT+ Health coach, BEHAVIORAL: CBT w/o Health Coach ( self-guided), BEHAVIORAL: Usual Care
Pain, Sickle Cell Disease
Sickle Cell Disease, Pain management, Cognitive Behavioral Therapy, Wellness
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Study Locations
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| Location | Contacts |
|---|---|
| Ann and Robert H. Lurie Children's Hospital of Chicago Chicago, Illinois | Kevin Guerrero - (kguerrero@lueriechildrens.org) |
| Children's Healthcare of Atlanta Atlanta, Georgia | Katyria Thornton - (katyria.thornton@choa.org) Vontarius Howard Jesse - (vontarius.howard@choa.org) |
| Connecticut Children's Medical Center Hartford, Connecticut | Christopher Theriault - (ctheriault@connecticutchildrens.org) |
| East Carolina University Health Medical Center Greenville, North Carolina | Toria Wilson - (wilsonto22@ecu.edu) |
| Rutgers New Jersey Medical School Newark, New Jersey | Kim White - (whiteka@rwjms.rutgers.edu) |
| The Regents of the University of Michigan Ann Arbor, Michigan | Anela Mukherjee - (mukherja@med.umich.edu) |
| UCLA Mattel Children's Hospital Ronald Reagan Hospital Los Angeles, California | Debbie Argueta Rufino - (darguetarufino@mednet.ucla.edu) |
| UPMC Children's Hospital of Pittsburgh Pittsburgh, Pennsylvania | Alex Berkebile - (berkebileak@upmc.edu) Amy Travis - (travisam@upmc.edu) |
| UPMC University of Pittsburgh Classical Hematology Adult Clinic Pittsburgh, Pennsylvania | Steffi Siebert, MPH - (presencestudy@pitt.edu) |
| University of Rochester Medical Center Rochester, New York | Priya Kaushal - (priya_kaushal@urmc.rochester.edu) |
| University of South Alabama Medical Center Mobile, Alabama | Jessica King - (jlking@health.southalabama.edu) T'Shemika Perryman - (tperryman@health.southalabama.edu) |
| Virginia Commonwealth University Richmond, Virginia | Danie Sop, PhD - (daniel.sop@vcuhealth.org) |
| Wake Forest Baptist Hospital Durham, North Carolina | Julie Fountain - (Julie.Fountain@Advocatehealth.org) |
| Weil Cornell Medical College New York, New York | Masiel Infante - (mai4011@med.cornell.edu) |
A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue
Pfizer CT.gov Call Center - ClinicalTrials.gov_Inquiries@pfizer.com
NCT06989437
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Key inclusion Criteria:
* Signed Informed Consent Document
* Documented active diagnosis of metastatic pancreatic ductal adenocarcinoma
* Cachexia defined by Fearon criteria of weight loss
* Completed 1 x 28-day cycle of first-line systemic nab-paclitaxel and gemcitabine chemotherapy or 2 x 14-day cycles of FOLFIRINOX chemotherapy and prior to receiving Cycle 2 chemotherapy
* ECOG PS ≤1 with life expectancy of at least 4 months
Key
Exclusion Criteria:
* Current active reversible causes of decreased food intake
* Cachexia caused by other reasons
* Any prior or current clinical diagnosis of heart failure, irrespective of left ventricular ejection fraction or New York Heart Association classification
* Left ventricular ejection fraction \<50%
* Receiving tube feedings or parenteral nutrition at the time of Screening or Randomization
* History of allergic or anaphylactic reaction to any therapeutic or diagnostic monoclonal antibody
* History of allergy or hypersensitivity to any of the chemotherapeutics or any of their excipients
* Neuroendocrine (carcinoid, islet cell) or acinar pancreatic carcinoma, symptomatic brain metastasis, leptomeningeal disease or other active CNS metastases
* Inadequate liver function
* Renal disease requiring dialysis or eGFR \<30 mL/min/1.73m2 DRUG: ponsegromab, DRUG: placebo
Cachexia, Metastatic Pancreatic Ductal Adenocarcinoma
pancreatic cancer, metastatic cancer, cancer, anorexia, cachexia, weight loss, loss of appetite, fatigue
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Study Locations
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| Location | Contacts |
|---|---|
| AZ Turnhout - Campus Sint-Elizabeth Turnhout, Antwerpen | |
| Addenbrooke's Hospital Cambridge, | |
| Affiliated Hospital of Hebei University Baoding, | |
| Aichi Cancer Center Hospital Nagoya, Aichi-ken | |
| Anhui Provincial Hospital Hefei, | |
| Antiguo Hospital Civil de Guadalajara "Fray Antonio Alcalde" Guadalajara, Jalisco | |
| Apotheke am Universitätsklinikum Leipzig Leipzig, Saxony | |
| Arthur J.E. Child Comprehensive Cancer Centre Calgary, Alberta | |
| Asan Medical Center Seoul, Seoul Teukbyeolsi | |
| Atlantic Health System / Morristown Medical Center Morristown, New Jersey | |
| Atlantic Health System / Overlook Medical Center Summit, New Jersey | |
| Azienda Ospedaliera Universitaria Careggi Florence, Tuscany | |
| Azienda Ospedaliera Universitaria Ospedali Riuniti - Foggia Foggia, | |
| Azienda Ospedaliero Universitaria delle Marche Ancona, | |
| Baylor Scott & White Vasicek Cancer Treatment Center Temple, Texas | |
| Beijing Tsinghua Changgung Hospital Beijing, | |
| CARTI Cancer center Little Rock, Arkansas | |
| CHA Bundang Medical Center, CHA University Seongnam-si, Kyǒnggi-do | |
| CIUSSS- saguenay-Lac-Saint-Jean Chicoutimi, Quebec | |
| Cancer Care Specialists of Illinois Decatur, Illinois | |
| Cancer Care Specialists of Illinois - Cancer Care Center of O'Fallon O'Fallon, Illinois | |
| Cancer Hospital Chinese Academy of Medical Science Langfang, Hebei | |
| Cancer Hospital Chinese Academy of Medical Science Langfang, Hebei | |
| Cardiology Associates, Inc ‘Aiea, Hawaii | |
| Cedars-Sinai Cancer at Cedars-Sinai Medical Center Los Angeles, California | |
| Central Arkansas Radiation Therapy Institute, dba CARTI Pine Bluff, Arkansas | |
| Central Arkansas Radiation Therapy Institute, dba CARTI Pine Bluff, Arkansas | |
| Central Arkansas Radiation Therapy Institute, dba CARTI Pine Bluff, Arkansas | |
| Central Arkansas Radiation Therapy Institute, dba CARTI Pine Bluff, Arkansas | |
| Centre Hospitalier Universitaire de Poitiers Poitiers, Vienne | |
| Centre Intégré de Santé et de Services Sociaux de la Montérégie-Centre Greenfield Park, Quebec | |
| Centro de Atención e Investigación Cardiovascular del Potosí S.C. San Luis Potosí City, | |
| Centro de Investigacion Clinica de Oaxaca Oaxaca City, Oaxaca | |
| Chao Family Comprehensive Cancer Center and Ambulatory Care Irvine, California | |
| Chiba Cancer Center Chiba, Chiba | |
| China Medical University Hospital Taichung, | |
| Chittaranjan National Cancer Institute Kolkata, West Bengal | |
| Cliniques Universitaires Saint-Luc Brussels, Bruxelles-capitale, Région de | |
| Decatur Memorial Hospital Decatur, Illinois | |
| Fakultna Nemocnica Trnava Trnava, | |
| Fakultna nemocnica Trencin Trenčín, Trenčín Region | |
| Fakultna nemocnica s poliklinikou Nove Zamky Nové Zámky, | |
| Fred Hutchinson Cancer Center Seattle, Washington | |
| Froedtert Hospital and the Medical College of Wisconsin Milwaukee, Wisconsin | |
| Fujian Cancer Hospital Fuzhou, Fujian | |
| Georgetown University Medical Center Washington D.C., District of Columbia | |
| Georgetown University Medical Center - Department of Pharmacy, Oncology Pharmacy Washington D.C., District of Columbia | |
| Grand Hopital de Charleroi Charleroi, Hainaut | |
| Guangdong General Hospital Guangzhou, | |
| Gustave Roussy Villejuif, Val-de-marne | |
| Guy's & St Thomas' NHS Foundation Trust London, | |
| H.R.U Málaga - Hospital General Málaga, | |
| Hadassah Medical Center Jerusalem, Jerusalem | |
| Hammersmith Hospital London, | |
| Henri Mondor Hospital Créteil, Val-de-marne | |
| Henry-Joyce Cancer Clinic Nashville, Tennessee | |
| Hope and Healing Clinical Research LLC Hinsdale, Illinois | |
| Hope and Healing Clinical Research LLC New Lenox- Research Department New Lenox, Illinois | |
| Hospital Clinic de Barcelona Barcelona, | |
| Hospital General Universitario Gregorio Marañon Madrid, | |
| Hospital Moinhos de Vento Porto Alegre, Rio Grande do Sul | |
| Hospital Santa Rita de Cassia Vitória, Espírito Santo | |
| Hospital Universitari Vall d'Hebron Barcelona, | |
| Hospital Universitario Central de Asturias Oviedo, Principality of Asturias | |
| Hospital Universitario Ramon y Cajal Madrid, | |
| Houston Methodist Hospital Houston, Texas | |
| Huzhou Central Hospital Huzhou, Zhejiang | |
| Hôpital Universitaire Paul Brousse Villejuif, | |
| ICON Cancer Centre - Kurralta Park Kurralta Park, South Australia | |
| Icahn School of Medicine at Mount Sinai New York, New York | |
| Icesp - Instituto Do Câncer Do Estado de São Paulo São Paulo, | |
| Icon Cancer Centre Hobart Hobart, Tasmania | |
| Inha University Hospital Jemulpo-gu, Incheon | |
| Inje University Haeundae Paik Hospital Busan, | |
| Institut Jules Bordet Brussels, | |
| Institut Paoli-Calmettes Marseille, Provence-Alpes-Côte d'Azur Region | |
| Invision, LLC Honolulu, Hawaii | |
| JHU Oncology Central Kit Services Baltimore, Maryland | |
| Jack & Sheryl Morris Cancer Center New Brunswick, New Jersey | |
| Jewish General Hospital Montreal, Quebec | |
| Johns Hopkins Hospital Baltimore, Maryland | |
| Kagawa University Hospital Kita-gun, Kagawa-ken | |
| Kanagawa Cancer Center Yokohama, | |
| Kaohsiung Medical University Chung-Ho Memorial Hospital Kaohsiung City, | |
| Keimyung University Dongsan Hospital Daegu, Taegu-kwangyǒkshi | |
| Klinik und Poliklinik für Diagnostische und Interventionelle Radiologie Leipzig, Saxony | |
| Klinikum rechts der Isar der Technischen Universitat Munchen München, | |
| Kyushu University Hospital Fukuoka, | |
| Levine Cancer Institute Charlotte, North Carolina | |
| Liga Norte Riograndense Contra O Cancer Natal, Rio Grande do Norte | |
| MHAT - Sveta Sofia EOOD Sofia, | |
| MHAT for Women's Health Nadezhda Sofia, | |
| Massey Cancer Center Clinical & Translational Research Lab Richmond, Virginia | |
| Mayo Clinic Rochester, Minnesota | |
| Mayo Clinic Rochester, Minnesota | |
| Mayo Clinic Cancer Center Outpatient Pharmacy Rochester, Minnesota | |
| Mayo Clinic Hospital Phoenix, Arizona | |
| Mayo Clinic Pharmacy Jacksonville, Florida | |
| Medical Center Futuremeds Plovdiv, | |
| MidAmerica Cancer Care - American Oncology Partners Kansas City, Missouri | |
| MidAmerica Cancer Care- American Oncology Partners Merriam, Kansas | |
| Muenchen Klinik Neuperlach, Klinik fuer Haematologie und Onkologie München, Bavaria | |
| Narodny Onkologicky Ustav Bratislava, | |
| Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - Panstwowy Instytut Badawczy w Warszawie Warsaw, Masovian Voivodeship | |
| National Cancer Center Hospital Chūōku, | |
| National Cancer Center Hospital East Kashiwa, Chiba | |
| National Cheng Kung University Hospital Tainan, | |
| National Hospital Organization Kyushu Cancer Center Fukuoka, | |
| National Taiwan University Hospital Taipei, | |
| Nebraska Medicine Omaha, Nebraska | |
| Nebraska Medicine - Village Pointe Omaha, Nebraska | |
| Nemocnica s poliklinikou Stefana Kukuru Michalovce, a.s. Michalovce, | |
| Niguarda Cancer Center, ASST Grande Ospedale Metropolitano Niguarda Milan, Milan | |
| OHSU Center for Health & Healing 1 Portland, Oregon | |
| OSHU Center for Health and Healing 2 Portland, Oregon | |
| Oncocentro Belo Horizonte, Minas Gerais | |
| Oncology Investigational Drug Service (IDS) Baltimore, Maryland | |
| Oregon Health and Science University Portland, Oregon | |
| Pan American Center for Oncology Trials, LLC San Juan, | |
| Pan American Center for Oncology Trials, LLC San Juan, | |
| Pan American Center for Oncology Trials, LLC - Dorado Office Dorado, | |
| Pan American Center for Oncology Trials, LLC - Mayaguez Office Mayagüez, | |
| Peking Union Medical College Hospital Beijing, | |
| Premier Imaging Kansas City, Missouri | |
| Princess Margaret Cancer Centre - University Health Network Toronto, Ontario | |
| Providence Medical Foundation Santa Rosa, California | |
| Qilu Hospital of Shandong University Jinan, Shandong | |
| RWJ University Hospital Somerset, Steeplechase Cancer Center Somerville, New Jersey | |
| Rabin Medical Center Petah Tikva, Central District | |
| Rajiv Gandhi Cancer Institute And Research Centre New Delhi, National Capital Territory of Delhi | |
| Rambam Health Care Campus Haifa, Heifa | |
| Renown Health Medical Oncology Reno, Nevada | |
| Renown Office of Clinical Research Reno, Nevada | |
| Renown Regional Medical Center Reno, Nevada | |
| Royal Free Hospital London, | |
| Royal Marsden Hospital (Chelsea) London, | |
| Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai, Shanghai Municipality | |
| Rutgers Cancer Institute New Brunswick, New Jersey | |
| Rwj University Hospital Somerset Somerville, New Jersey | |
| Samsung Medical Center Seoul, | |
| Sana Klinikum Lichtenberg Berlin, | |
| Sawai Man Singh Medical College Hospital (SMS Hospital) Jaipur, Rajasthan | |
| Second Hospital of Lanzhou University Lanzhou, Gansu | |
| Seoul National University Bundang Hospital Seongnam, | |
| Seoul National University Hospital Seoul, | |
| Severance Hospital, Yonsei University Health System Seoul, | |
| Shaare Zedek Medical Center Jerusalem, | |
| Shanghai General Hospital Shanghai, | |
| Sheba Medical Center Ramat Gan, | |
| Shizuoka Cancer Center Nagaizumi-cho, Shizuoka | |
| Shoalhaven District Memorial Hospital Nowra, New South Wales | |
| Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Baltimore, Maryland | |
| Sir Run Run Shaw Hospital of Zhejiang University School of Medicine Hangzhou, Zhejiang | |
| Sourasky Medical Center Tel Aviv, TELL ABĪB | |
| Specjalistyczny Szpital Onkologiczny NU-MED Sp. z o.o. Tomaszów Mazowiecki, | |
| St. Joseph Medical Center Kansas City, Missouri | |
| St. Marianna University Hospital Kawasaki, Kanagawa | |
| Sunnybrook Research Institute Toronto, Ontario | |
| Szpital Kliniczny Ministerstwa Spraw Wewnętrznych i Administracji z Warmińsko - Mazurskim Centrum Onkologii w Olsztynie Olsztyn, Warmian-Masurian Voivodeship | |
| Szpital Wojewódzki im. Mikołaja Kopernika w Koszalinie Koszalin, | |
| Taipei Veterans General Hospital Taipei, | |
| Tata Memorial Hospital Mumbai, Maharashtra | |
| The Cancer Institute Hospital of JFCR Koto-ku, Tokyo | |
| The Catholic Univ. of Korea Seoul St. Mary's Hospital Seoul, Seoul-teukbyeolsi [seoul] | |
| The Clatterbridge Cancer Centre Liverpool, | |
| The First Affiliated Hospital of Wenzhou Medical University Wenzhou, | |
| The First Affiliated Hospital of Xi'An Jiaotong University Xi'an, Shaanxi | |
| The First Affiliated Hospital of Zhengzhou University Zhengzhou, Henan | |
| The First Hospital of Shanxi Medical University Taiyuan, Shanxi | |
| The Kirklin Clinic of UAB Hospital Birmingham, Alabama | |
| The Ottawa Hospital - General Campus Ottawa, Ontario | |
| The Second Hospital of Dalian Medical University Dalian, Liaoning | |
| The University of Alabama at Birmingham Birmingham, Alabama | |
| The University of Hong Kong-Shenzhen Hospital Shenzhen, Guangdong | |
| The University of Osaka Hospital Suita, Osaka | |
| UC Irvine Health Orange, California | |
| UC San Diego Koman Family Outpatient Pavilion La Jolla, California | |
| UC San Diego McGrath Outpatient Pavilion - Hillcrest San Diego, California | |
| UC San Diego Medical Center - Bankers Hill San Diego, California | |
| UC San Diego Medical Center - Encinitas Encinitas, California | |
| UC San Diego Medical Center - Hillcrest San Diego, California | |
| UC San Diego Medical Center - La Jolla (Jacobs Medical Center / Thornton Pavilion) La Jolla, California | |
| UC San Diego Medical Center - Rancho Bernardo San Diego, California | |
| UC San Diego Medical Center - Vista Vista, California | |
| UC San Diego Moores Cancer Center La Jolla, California | |
| UC San Diego Sulpizio Cardiovascular Center La Jolla, California | |
| UCI Health - Irvine Irvine, California | |
| UCLA Department of Medicine - Hematology/Oncology Los Angeles, California | |
| UCLA Hematology/Oncology - Santa Monica Santa Monica, California | |
| UNC Hospitals, The University of North Carolina at Chapel Hill Chapel Hill, North Carolina | |
| UZ Leuven Leuven, | |
| United Imaging Consultants Lenexa, Kansas | |
| Unity Health Toronto, St. Michael's Hospital Toronto, Ontario | |
| Universitaetsklinikum Carl Gustav Carus, Technischen Universitaet Dresden Dresden, Saxony | |
| Universitaetsklinikum Duesseldorf Düsseldorf, North Rhine-Westphalia | |
| University Cancer & Blood Center, LLC Athens, Georgia | |
| University Hospital,Kyoto Prefectural University of Medicine Kyoto, | |
| University Multiprofile Hospital for Active Treatment Sofiamed Sofia, | |
| University of Hawaii Cancer Center Honolulu, Hawaii | |
| University of Kentucky Healthcare - Markey Cancer Center Lexington, Kentucky | |
| University of Kentucky Medical Center Lexington, Kentucky | |
| University of Kentucky Research Foundation Lexington, Kentucky | |
| University of Kentucky, Markey Cancer Center Clinical Research Office (UK MCC CRO) Lexington, Kentucky | |
| University of Nebraska Medical Center Omaha, Nebraska | |
| University of North Carolina Hospitals at Hillsborough Hillsborough, North Carolina | |
| University of Rochester Medical Center Rochester, New York | |
| University of Texas Southwestern Medical Center Dallas, Texas | |
| University of Texas Southwestern Medical Center - Simmons Cancer Center Dallas, Texas | |
| University of Texas Southwestern Medical Center-WIlliam P. Clements Jr. University Hospital Dallas, Texas | |
| University of Texas Southwestern Medical Center-Zale Lipshy University Hospital Dallas, Texas | |
| University of Washington Medical Center Seattle, Washington | |
| Universität Leipzig - Med. Fakultät Leipzig, Saxony | |
| Uniwersytecki Szpital Kliniczny W Poznaniu Poznan, | |
| VCU Health Short Pump Pavilion Richmond, Virginia | |
| VCU Health Stony Point Richmond, Virginia | |
| VCU Health Tappahannock Hospital Tappahannock, Virginia | |
| VCU Medical Center Gateway Building Richmond, Virginia | |
| Vardhman Mahavir Medical College and Safdarjung Hospital New Delhi, National Capital Territory of Delhi | |
| Venkateshwar Hospital New Delhi, National Capital Territory of Delhi | |
| Virginia Commonwealth University Richmond, Virginia | |
| Virginia Commonwealth University Richmond, Virginia | |
| Virginia Mason Medical Center Seattle, Washington | |
| Vychodoslovensky Onkologicky ustav a.s. Košice, | |
| Wakayama Medical University Hospital Wakayama, | |
| Wakayama Minami Radiology Clinic Wakayama-shi Kimiidera 870-2, Wakayama | |
| Western General Hospital Edinburgh, Midlothian | |
| Western Health-Sunshine & Footscray Hospitals St Albans, Victoria | |
| Westmead Hospital Northmead, New South Wales | |
| Yamaguchi University Hospital Ube, Yamaguchi | |
| Zhongshan Hospital Fudan University Shanghai, |