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13 Study Matches
Colorectal Health Research Champions
Hunley, Rachel - rachel.hunley@vcuhealth.org
Sheppard, Vanessa, B.
NCT04812743
HM20017398
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Inclusion Criteria:
the individual is > 30 years of age
• They are literate
• They are/were directly or indirectly impacted by colorectal cancer and interested in becoming a champion for colorectal cancer research. To participate in a chat hosted by the CHRC the inclusion criteria is:
• adult of any gender
• over 30 years of age. Exclusion Criteria for chat hosted by the CHRC: -Those < 30 years of age
Behavioral: Colorectal Health Research Champions
Cancer of Colon, Cancer of Rectum, Rectum, Colon
Prevention
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Katelyn Schifano, MS - (schifanokr@vcu.edu) |
Phase 3 Study of MRTX849 +Cetuximab vs Chemo in Patients W/ Advanced Colorectal Cancer w/ KRAS G12C
Donovan, Carrie - cdonovan2@vcu.edu
Matin, Khalid
NCT04793958
HM20022574
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Inclusion Criteria:
• Histologically confirmed diagnosis of colorectal carcinoma with KRAS G12C mutation in tumor tissue.
• Prior receipt of 1st line treatment in advanced CRC with a fluoropyrimidine-based chemotherapy regimen containing either oxaliplatin or irinotecan, and radiographically documented progression of disease on or after treatment.
Exclusion Criteria:
• Prior treatment with a therapy targeting KRAS G12C mutation (e.g., AMG 510).
• Prior treatment with an anti-EGFR antibody (e.g., cetuximab or panitumumab).
• Active brain metastasis
Drug: MRTX849, Biological: Cetuximab, Drug: mFOLFOX6 Regimen, Drug: FOLFIRI Regimen,
drug: Mrtx849,
drug: Leucovorin,
drug: Folinic acid,
drug: Cetuximab,
drug: 5-fluorouracil
Advanced Colorectal Cancer, Metastatic Colorectal Cancer, Rectum, Colon
Colorectal Cancer, Colorectal Cancer Trial, Colorectal Carcinoma, Rectal Cancer, Colon Cancer, KRAS, KRAS G12C, RAS, Colorectal Adenocarcinoma
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Study Locations
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| Location | Contacts |
|---|---|
| AdventHealth Cancer Institute Orlando, Florida | |
| Alabama Oncology, Bruno Cancer Center Birmingham, Alabama | |
| Baylor Scott & White Medical Center Temple, Texas | |
| Cancer Partners of Nebraska Lincoln, Nebraska | |
| Cleveland Clinic Florida Weston, Florida | |
| Community Cancer Institute Clovis, California | |
| Compass Oncology- Vancouver Cancer Center Vancouver, Washington | |
| Comprehensive Blood and Cancer Center - Bakersfield Bakersfield, California | |
| Comprehensive Cancer Centers of Nevada Las Vegas, Nevada | |
| Comprehensive Hematology Oncology St. Petersburg, Florida | |
| Eastern CT Hematology and Oncology Associates Norwich, Connecticut | |
| Emad Ibrahim, MD, Inc. Redlands, California | |
| Florida Cancer Affiliates- Ocala Ocala, Florida | |
| Florida Cancer Specialists West Palm Beach, Florida | |
| Florida Cancer Specialists West Palm Beach, Florida | |
| Florida Cancer Specialists West Palm Beach, Florida | |
| Florida Cancer Specialists (Administration and Drug Shipment) Saint Petersburg, Florida | |
| Fundaci?n de Investigaci?n de Diego (FDI) Clinical Research San Juan, | |
| Hematology Oncology Associates of Fredericksburg Fredericksburg, Virginia | |
| Henry Ford Hospital Detroit, Michigan | |
| Highlands Oncology Group Springdale, Arkansas | |
| Inova Schar Cancer Institute Fairfax, Virginia | |
| Laura & Isaac Perlmutter Cancer Center at NYU Langone Health New York, New York | |
| Massachusetts General Hospital Boston, Massachusetts | |
| Mayo Clinic Rochester, Minnesota | |
| Mayo Clinic Rochester, Minnesota | |
| Mayo Clinic Building - Phoenix Phoenix, Arizona | |
| Memorial Sloan Kettering Cancer Center - New York New York, New York | |
| Mercy Clinic Cancer & Hematology - Chub O'Reilly Cancer Center Springfield, Missouri | |
| Midwestern Regional Medical Center, Inc. DBA CTCA, Chicago Zion, Illinois | |
| Millennium Physicians - North Houston Houston, Texas | |
| MultiCare Regional Cancer Center - Tacoma Puyallup, Washington | |
| New Jersey Cancer Center and Blood Disorders Belleville, New Jersey | |
| North Shore Hematology and Oncology Assoc. P.C. DBA NY Cancer and Blood Specialists Port Jefferson Station, New York | |
| Olive View - University of California Los Angeles Medical Center Sylmar, California | |
| Orlando Health Cancer Institute Orlando, Florida | |
| Pacific Hematology Oncology Associates San Francisco, California | |
| Puerto Rico Medical Research Center Hato Rey, | |
| Regions Hospital - Cancer Care Center Saint Paul, Minnesota | |
| Rocky Mountain Cancer Centers Colorado Springs, Colorado | |
| Rutgers Cancer Institute of New Jersey New Brunswick, New Jersey | |
| SCRI - Hematology Oncology Clinic - Baton Rouge Baton Rouge, Louisiana | |
| SCRI - Tennessee Oncology - Chattanooga - Memorial Plaza Chattanooga, Tennessee | |
| SCRI Tennessee Oncology Nashville Centennial Nashville, Tennessee | |
| Sharp Memorial Hospital San Diego, California | |
| Southeastern Regional Medical Center, Inc. DBA Cancer Treatment Centers of America Newnan, Georgia | |
| St. Francis Cancer Center Indianapolis, Indiana | |
| St. Joseph Heritage Healthcare Fullerton, California | |
| Summit Medical Group Berkeley Heights, New Jersey | |
| Sylvester Comprehensive Cancer Center Plantation, Florida | |
| TRIO-US Central Administration Whittier, California | |
| Texas Oncology- Baylor Charles A. Sammons Cancer Center Dallas, Texas | |
| The University of Texas MD Anderson Cancer Center Houston, Texas | |
| Torrance Memorial Physician Network - Cancer Care and Infusion Center Torrance, California | |
| USC/Norris Comprehensive Cancer Center Los Angeles, California | |
| University of Colorado Hospital Anschutz Cancer Pavilion Aurora, Colorado | |
| University of Oklahoma Health Sciences Center - OU Health Stephenson Cancer Center Oklahoma City, Oklahoma | |
| Virginia Cancer Institute Richmond, Virginia | |
| Virginia Commonwealth University Richmond, Virginia | Donovan, Carrie - (cdonovan2@vcu.edu) |
| Virginia Commonwealth University, Massey Cancer Center Richmond, Virginia | |
| Western Regional Medical Center, Inc. DBA Cancer Treatment Centers of America, Phoenix Goodyear, Arizona | |
| Winship Cancer Institute Atlanta, Georgia |
Testing the Addition of Anti-cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment, Cetuximab Plus Encorafenib, for Colorectal Cancer
ctrrecruit@vcu.edu
NCT06102902
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Inclusion Criteria:
* Patients must have histologically confirmed and radiographically measurable metastatic colorectal adenocarcinoma with known BRAF V600E mutation, confirmed in a Clinical Laboratory Improvement Amendments (CLIA) certified laboratory with at least one tumor measurable as defined by Response Evaluation Criteria in Solid Tumors (RECIST) version 1.1, and for which standard curative or palliative measures do not exist or are no longer effective
* Age ≥ 18 years. Because no dosing or adverse event data are currently available on the use of ZEN003694 in combination with cetuximab and encorafenib in patients \< 18 years of age, children are excluded from this study
* Eastern Cooperative Oncology Group (ECOG) performance status ≤ 2 (Karnofsky ≥ 60%)
* Absolute neutrophil count ≥ 1,500/mcL
* Platelets ≥ 100,000/mcL
* Hemoglobin (Hb) ≥ 9 mg/dl
* Total bilirubin ≤ 1.5 mg/dl (excluding Gilbert's disease)
* Aspartate aminotransferase (AST) (serum glutamic-oxaloacetic transaminase \[SGOT\])/alanine aminotransferase (ALT) (serum glutamate pyruvate transaminase \[SGPT\]) ≤ 3 x institutional upper limit of normal (ULN)
* Creatinine clearance (CrCL) glomerular filtration rate (GFR) ≥ 50 mL/min/1.73 m\^2
* Human immunodeficiency virus (HIV)-infected patients on effective anti-retroviral therapy with undetectable viral load within 6 months are eligible for this trial
* For patients with evidence of chronic hepatitis B virus (HBV) infection, the HBV viral load must be undetectable on suppressive therapy, if indicated
* Patients with a history of hepatitis C virus (HCV) infection must have been treated and cured. For patients with HCV infection who are currently on treatment, they are eligible if they have an undetectable HCV viral load
* Patients with treated brain metastases are eligible if follow-up brain imaging after central nervous system (CNS)-directed therapy shows no evidence of progression
* Patients with new or progressive brain metastases (active brain metastases) or leptomeningeal disease are eligible if the treating physician determines that immediate CNS specific treatment is not required and is unlikely to be required during the first cycle of therapy
* Patients with a prior or concurrent malignancy whose natural history or treatment does not have the potential to interfere with the safety or efficacy assessment of the investigational regimen are eligible for this trial
* Patients with known history or current symptoms of cardiac disease, or history of treatment with cardiotoxic agents, should have a clinical risk assessment of cardiac function using the New York Heart Association Functional Classification. Patients should be New York Heart Association Functional Classification of class II or better
* Patients must have progressed after at least 1 prior systemic treatment for incurable advanced or metastatic disease
* Patients must have received prior treatment with the combination of encorafenib and cetuximab. They must have tolerated the combination at doses planned for the study
* The effects of ZEN003694 on the developing human fetus are unknown. For this reason and because BRD and BET inhibitor agents as well as other therapeutic agents used in this trial are known to be teratogenic, women of child-bearing potential and men must agree to use adequate contraception (hormonal or barrier method of birth control; abstinence) prior to study entry, for the duration of study participation, and for at least 4 months following the last dose of study drug. Women must have a negative serum or urine pregnancy test (minimum sensitivity 25 IU/L or equivalent units of human chorionic gonadotropin \[HCG\]) within 72 hours prior to the start of investigational product. Should a woman become pregnant or suspect she is pregnant while she or her partner is participating in this study, she should inform her treating physician immediately
* Ability to understand and the willingness to sign a written informed consent document. Legally authorized representatives may sign and give informed consent on behalf of study participants
Exclusion Criteria:
* Patients who have not recovered from adverse events due to prior anti-cancer therapy (i.e., have residual toxicities \> grade 1) with the exception of alopecia
* Patients who are receiving any other investigational agents
* History of allergic reactions attributed to compounds of similar chemical or biologic composition to ZEN003694 or other agents used in study
* Patients with uncontrolled intercurrent illness including, but not limited to, active bleeding diatheses, poorly controlled infection/disorders, or nonmalignant medical illnesses that are uncontrolled or whose control may be jeopardized by the treatment with the study therapy
* Patients receiving any medications or substances that are strong inhibitors or inducers of CYP3A4 or substrates of CYP1A2 with narrow therapeutic windows are ineligible. Strong inhibitors or inducers of CYP3A4 must be discontinued at least 7 days prior to the first dose of ZEN003694. As proton pump inhibitors (PPIs), H2 receptor antagonists, and antacids may alter the pharmacokinetics of ZEN003694 by reducing ZEN003694 exposure, patients receiving proton pump inhibitors are ineligible. If H2 blockers or other acid reducing agents are used concomitantly with ZEN003694, a staggered dosing schedule should be used, either dose ZEN003694 2 hours before the H2 blocker or 10-12 hours after an H2 blocker. Because the lists of these agents are constantly changing, it is important to regularly consult a frequently-updated medical reference. As part of the enrollment/informed consent procedures, the patient will be counseled on the risk of interactions with other agents, and what to do if new medications need to be prescribed or if the patient is considering a new over-the-counter medicine or herbal product
* Pregnant women are excluded from this study because ZEN003694 is BRD and BET inhibitor agent with the potential for teratogenic or abortifacient effects. Because there is an unknown but potential risk for adverse events in nursing infants secondary to treatment of the mother with ZEN003694, breastfeeding should be discontinued if the mother is treated with ZEN003694. These potential risks may also apply to other agents used in this study DRUG: BET Bromodomain Inhibitor ZEN-3694, PROCEDURE: Biopsy Procedure, PROCEDURE: Biospecimen Collection, BIOLOGICAL: Cetuximab, PROCEDURE: Computed Tomography, PROCEDURE: Echocardiography Test, DRUG: Encorafenib, PROCEDURE: Magnetic Resonance Imaging, PROCEDURE: Multigated Acquisition Scan
Metastatic Colorectal Adenocarcinoma, Recurrent Colorectal Adenocarcinoma, Refractory Colorectal Adenocarcinoma, Stage IV Colorectal Cancer AJCC v8
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Study Locations
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| Location | Contacts |
|---|---|
| Los Angeles General Medical Center Los Angeles, California | |
| M D Anderson Cancer Center Houston, Texas | Site Public Contact - (askmdanderson@mdanderson.org) |
| Ohio State University Comprehensive Cancer Center Columbus, Ohio | Site Public Contact - (Jamesline@osumc.edu) |
| UCHealth University of Colorado Hospital Aurora, Colorado | |
| USC / Norris Comprehensive Cancer Center Los Angeles, California | |
| University of Kansas Cancer Center Kansas City, Kansas | Site Public Contact - (KUCC_Navigation@kumc.edu) |
| University of Kansas Clinical Research Center Fairway, Kansas | Site Public Contact - (KUCC_Navigation@kumc.edu) |
| University of Kansas Hospital-Indian Creek Campus Overland Park, Kansas | Site Public Contact - (KUCC_Navigation@kumc.edu) |
| University of Kansas Hospital-Westwood Cancer Center Westwood, Kansas | Site Public Contact - (KUCC_Navigation@kumc.edu) |
| University of Oklahoma Health Sciences Center Oklahoma City, Oklahoma | Site Public Contact - (ou-clinical-trials@ouhsc.edu) |
| University of Virginia Cancer Center Charlottesville, Virginia | Site Public Contact - (uvacancertrials@hscmail.mcc.virginia.edu) |
| VCU Massey Comprehensive Cancer Center Richmond, Virginia | Site Public Contact - (CTOclinops@vcu.edu) |
A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer
Takeda Contact - medinfoUS@takeda.com
NCT06562543
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Inclusion Criteria:
• Provide written (or electronic) informed consent.
• Male or female aged more than or equal to (≥)18 years.
• Presence of histologically and/or cytologically documented metastatic colorectal adenocarcinoma. Rat sarcoma virus (RAS) status for each participant must be documented.
• Have been previously treated with standard approved therapies: * Fluoropyrimidine-, oxaliplatin-, and irinotecan-based chemotherapy, * An anti-vascular endothelial growth factor (VEGF) biological therapy (e.g., bevacizumab, aflibercept, ramucirumab \[regorafenib is NOT an anti-VEGF biologic\]), and * If RAS wild-type and medically appropriate, an anti-epidermal growth factor receptor (EGFR) therapy (e.g., cetuximab, panitumumab). * If known microsatellite instability-high (MSI-H) or deficient mismatch repair (dMMR) tumor and medically appropriate, a programmed cell death protein 1 (PD1) inhibitor.
• Self-identify as Black and/or African American or Hispanic and/or Latino or as both.
• Body weight ≥40 kilograms (kg).
• Eastern Cooperative Oncology Group (ECOG) performance status of 0 to 1 at screening.
• Have assessable disease according to RECIST version 1.1, assessed locally.
• In participants of childbearing potential, agreement to use highly effective form(s) of contraception, which results in a low failure rate (less than \[\<\]1 percent \[%\] per year) when used consistently and correctly, starting during the screening period, continuing throughout the entire trial period, and for 2 weeks after taking the last dose of the trial intervention. Such methods include oral (PO) hormonal contraception (combined estrogen/progestogen or progestogen-only) associated with inhibition of ovulation, intrauterine device, intrauterine hormone-releasing system (IUS), bilateral tubal ligation, vasectomized partner, or true sexual abstinence in line with the preferred and usual lifestyle of the participant. Those assigned male sex at birth must always use a condom.
Exclusion Criteria:
• Absolute neutrophil count (ANC) \<1.5 times 10\^9 per liter (10\^9/L), platelet count \<100 times 10\^9/L, or hemoglobin \<9.0 grams per deciliter (g/dL). Blood transfusion within 1 week prior to enrollment for the purpose of increasing the likelihood of eligibility is not allowed.
• Serum total bilirubin more than (\>)1.5 times the upper limit of normal range (ULN). Participants with previously documented Gilbert syndrome and bilirubin \<2 times ULN are eligible.
• Alanine aminotransferase (ALT) or aspartate aminotransferase (AST) \>2.5 times ULN in participants without hepatic metastases; ALT or AST \>5 times ULN in participants with hepatic metastases.
• Creatinine clearance \<30 milliliters per minute (mL/min). Creatinine clearance can either be measured in a 24-hour urine collection or estimated by the Cockcroft-Gault equation. Where available and appropriate, other formulae may be used to estimate clearance after consultation with the trial medical monitor.
• Urine dipstick or urinalysis with protein ≥2 positive or 24-hour urine protein ≥1.0 gram per 24 hours (g/24 hours). Participants with 1+ positive proteinuria must undergo a 24-hour urine collection to assess urine protein level.
• Uncontrolled hypertension, defined as systolic BP ≥140 millimeter of mercury (mmHg) and/or diastolic blood pressure (BP) ≥90 mmHg despite optimal medical management. The participant must have BP below both limits. Repeated assessments are permitted.
• International normalized ratio (INR) \>1.5 times ULN or activated partial thromboplastin time (aPTT) \>1.5 times ULN, unless the participant is currently receiving or intended to receive anticoagulants for prophylactic purposes.
• History of or active gastric/duodenal ulcer or ulcerative colitis, active hemorrhage of an unresected gastrointestinal tumor, history of perforation or fistulas, or any other condition that could, in the investigator's judgment, result in gastrointestinal hemorrhage or perforation within the 6 months prior to screening.
• History or presence of hemorrhage from any other site (e.g, hemoptysis or hematemesis) within 2 months prior to screening.
• History of a thromboembolic event, including deep vein thrombosis, pulmonary embolism, or arterial embolism within 6 months prior to screening.
• Stroke and/or transient ischemic attack within 12 months prior to screening.
• Clinically significant cardiovascular disease, including but not limited to, acute myocardial infarction or coronary artery bypass surgery within 6 months prior to enrollment, severe or unstable angina pectoris, New York Heart Association Class III/IV congestive heart failure, ventricular arrhythmias requiring treatment, or left ventricular ejection fraction \<50% by echocardiogram.
• QT interval, corrected using the Fridericia method (QTcF) \>480 milliseconds or any factors that increase the risk of QT interval, corrected based on the patient's heart rate (QTc) prolongation or risk of arrhythmic events such as hypokalemia, congenital long QT syndrome, or family history of long QT syndrome.
• Systemic antineoplastic therapies (except for that described in exclusion criterion no. 15) or any investigational therapy within 2 weeks prior to the first dose of the trial intervention, including chemotherapy, radical radiotherapy, hormonotherapy, biotherapy, and immunotherapy.
• Systemic small molecule targeted therapies (e.g., tyrosine kinase inhibitors \[TKIs\]) within 5 half-lives or 4 weeks (whichever is shorter) prior to the first dose of the trial intervention.
• Palliative radiotherapy for bone metastasis/lesion within 2 weeks prior to the initiation of the trial intervention.
• Brachytherapy (i.e., implantation of radioactive seeds) within 60 days prior to the first dose of the trial intervention.
• Surgery or invasive procedure (i.e., a procedure that includes a biopsy; central venous catheter placement is allowed) within 14 days prior to the first dose of the trial intervention or unhealed surgical incision.
• Any unresolved toxicities from previous antitumor treatments greater than NCI CTCAE, version 5.0, Grade 1 (except for alopecia or neurotoxicity Grade less than or equal to \[≤\]2).
• Known human immunodeficiency virus infection.
• Known history of active viral hepatitis. For participants with evidence of chronic hepatitis B virus (HBV) infection, the HBV viral load had to be undetectable on suppressive therapy, if indicated. Participants with hepatitis C virus (HCV) infection who are currently on treatment are eligible if they have an undetectable HCV viral load.
• Clinically uncontrolled active infection requiring intravenous (IV) antibiotics.
• Tumor invasion of a large vascular structure (e.g., pulmonary artery or superior or inferior vena cava).
• Those who are currently pregnant or lactating.
• Brain metastases and/or spinal cord compression untreated with surgery and/or radiotherapy, and without clinical imaging evidence of SD for 14 days or longer; participants requiring steroids within 4 weeks prior to the start of the trial intervention are to be excluded.
• Other malignancy, except for non-melanoma skin cancer, in situ cervical carcinoma, or bladder carcinoma (tumor in situ and T1) that had been adequately treated during the 5 years prior to screening. Participants with another primary malignancy that has been adequately treated may be included after consultation with the trial medical monitor.
• Inability to take medication PO, dysphagia, or an active gastric ulcer resulting from previous surgery (e.g., gastric bypass) or a severe gastrointestinal disease, or any other condition that investigators believe might affect absorption of the investigational medicinal product (IMP).
• Other disease, metabolic disorder, physical examination anomaly, abnormal laboratory result, or any other condition (e.g., current alcohol or drug abuse) that investigators suspect might prohibit use of the IMP, affect interpretation of trial results, or put the participant at undue risk of harm based on the investigator's assessment.
• Known hypersensitivity to fruquintinib or any of its inactive ingredients, including the azo dyes Tartrazine- Federal Food, Drug, and Cosmetic Act (FD\&C) Yellow 5 and Sunset yellow For Coloring Food (FCF)-FD\&C Yellow 6.
• Received prior fruquintinib.
• Live vaccine ≤28 days before the first dose of the trial intervention. Seasonal vaccines for influenza are generally inactivated vaccines and are allowed. Intranasal vaccines are live vaccines and are not allowed.
• Use of strong inducers of cytochrome P450 3A4 (CYP3A4) within 2 weeks before the first dose of the trial intervention.
DRUG: Fruquintinib
Colorectal Cancer
colorectal cancer, fruquintinib
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Study Locations
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| Location | Contacts |
|---|---|
| Albert Einstein College of Medicine The Bronx, New York | |
| BRCR Global Plantation, Florida | |
| Baptist Health - Miami Cancer Institute Miami, Florida | |
| Baylor College of Medicine Houston, Texas | Site Contact - (karen.riggins@bcm.edu) |
| Boston Medical Center Boston, Massachusetts | |
| Capital Health Medical Center - Hopewell Pennington, New Jersey | Site Contact - (ALoaiza-Bonilla@capitalhealth.org) |
| Central Alabama Research Birmingham, Alabama | Site Contact - (kashraf@centralalabamaresearch.com) |
| Christiana Care Health Services Newark, Delaware | Site Contact - (jmisleh@cbg.org) |
| Columbia University New York, New York | |
| Emory University Atlanta, Georgia | Site Contact - (olatunji.alese@emory.edu) |
| Fox Chase Cancer Center | Philadelphia, PA Philadelphia, Pennsylvania | |
| Fundacion de Investigacion de Diego (FDI Clinical Research) San Juan, | Site Contact - (macosta@fdipr.com) |
| Hattiesburg Clinic Hattiesburg, Mississippi | Site Contact - (bo.hrom@hattiesburgclinic.com) |
| Hightower Clinical Research Oklahoma City, Oklahoma | Site Contact - (lam@hightowerclinical.com) |
| Hope and Healing Cancer Services Hinsdale, Illinois | Site Contact - (sgundala@hopenheal.care) |
| Indiana University Indianapolis, Indiana | Site Contact - (aalhader@iu.edu) |
| Ironwood Cancer and Research Centers Chandler, Arizona | Site Contact - (dharia@ironwoodcrc.com) |
| James J Peters Veterans Administration Medical Center - NAVREF The Bronx, New York | |
| Jefferson Health Philadelphia, Pennsylvania | Site Contact - (Atrayee.BasuMallick@jefferson.edu) |
| Medical University of South Carolina Charleston, South Carolina | |
| Medstar Speciality Hospital Northwest, Washington | Site Contact - (marcus.s.noel@gunet.georgetown.edu) |
| Mercy Medical Center Durango, Colorado | Site Contact - (pledakis@mdmercy.com) |
| Midwest Oncology Associates - Kansas City Kansas City, Missouri | Site Contact - (jaswinder.singh@amrllc.com) |
| Oncology Consultants - Memorial City Location Houston, Texas | Site Contact - (jpeguero@OncologyConsultants.com) |
| Our Lady of the Lake Physician Group - LSU Health Baton Rouge Oncology Baton Rouge, Louisiana | Site Contact - (stagg.patrick@yahoo.com) |
| PIH Health Whittier Hospital Downey, California | Site Contact - (Andrew.Pham@pihhealth.org) |
| Renovatio Clinical The Woodlands, Texas | Site Contact - (mary.crow@renovatioclinical.com) |
| Renovatio Clinical The Woodlands, Texas | Site Contact - (jonathan.lu@renovatioclinical.com) |
| SSM Health St. Louis DePaul Hospital St Louis, Missouri | Site Contact - (brian.smith@ssmhealth.com) |
| Saint Luke's Cancer Institute Kansas City, Missouri | |
| Tranquil Research Webster, Texas | Site Contact - (drknecht@cls.health) |
| UC Irvine Medical Center - Chao Family Comprehensive Cancer Orange, Virginia | Site Contact - (fdayyani@uci.edu) |
| University of Alabama at Birmingham Birmingham, Alabama | Site Contact - (ggupta@uabmc.edu) |
| University of Arizona Tucson, Arizona | Site Contact - (ajscott@arizona.edu) |
| University of California San Diego San Diego, California | Site Contact - (gbotta@ucsd.edu) |
| University of Florida Gainesville, Florida | Site Contact - (thomas.george@medicine.ufl.edu) |
| University of Miami Miami, Florida | |
| University of Southern California Los Angeles, California | Site Contact - (algaze@usc.edu) |
| University of Tennessee -- Memphis Memphis, Tennessee | Site Contact - (schokshi@uthsc.edu) |
| University of Texas Southwestern Medical Center Dallas, Texas | Site Contact - (Nilesh.Verma@UTSouthwestern.edu) |
| Vanderbilt University Medical Center Nashville, Tennessee | Site Contact - (brooke.d.looney@vumc.org) |
| Virginia Commonwealth University Richmond, Virginia | Site Contact - (khalid.matin@vcuhealth.org) |
| Washington University School of Medicine St Louis, Missouri | Site Contact - (nikolaos@wustl.edu) |
| Willis Knighton Cancer Center Shreveport, Louisiana | Site Contact - (jfeagin@wkhs.com) |
| Zangmeister Cancer Center Columbus, Ohio | Site Contact - (smikhail@zangcenter.com) |
Addition of Antibiotics to Upfront Treatment Regimen for Colorectal Cancer
Massey IIT Research Operations - masseyepd@vcu.edu
NCT06728072
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Inclusion Criteria:
* Diagnosis of stage IV colorectal cancer
* Measurable disease by Response evaluation criteria in solid tumors (RECIST) 1.1 criteria
* Planned first-line treatment with a 5FU-based doublet chemotherapy regimen for colon cancer, specifics of the regimen at the discretion of the treating physician Note: Patients who have received adjuvant therapy \>6 months prior are eligible
* Eastern Cooperative Oncology Group (ECOG) performance status (PS) 0-2
* Absolute neutrophil count (ANC) ≥1,500 cells/μL
* Platelet count ≥100,000 cells/μL
* Hemoglobin ≥8 g/dL Note: The use of transfusion or other intervention to achieve hemoglobin ≥8 g/dL is acceptable.
* Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) ≤2.5 × upper limit of normal (ULN) Note: Patients with documented liver metastases: AST and ALT ≤5 × ULN
* Serum creatinine ≤1.5 x ULN or calculated creatinine clearance ≥40 mL/min using the Cockcroft-Gault equation: (140 - age) × body weight/plasma creatinine × 72 (× 0.85 if female)
* Radiographically measurable disease by RECIST 1.1
* Nonpregnant and not actively breastfeeding
* Sexually active patients of childbearing potential and their partners must agree to use medically acceptable form of contraception, per treating investigator, throughout the study Patients should continue to use medically acceptable methods of contraception after study treatment ends, following the guidance for their specific chemotherapy regimen.
Childbearing potential excludes:
Age \> 50 years and naturally amenorrhoeic for \> 1 year OR previous hysterectomy or bilateral salpingo-oophorectomy
Exclusion Criteria:
* ongoing full dose anticoagulation Note: Patients on full dose anticoagulation may be approached to discuss study participation if lowering anticoagulation dose is feasible per the discretion of the treating investigator. Patients will be required to lower the anticoagulation dose by half 48 hours before beginning study drugs
* Total colectomy
* Diagnosed with Cockayne Syndrome
* Using disulfiram, tizanidine, or theophylline and unable to stop taking these medications for the length of the microbiome modulation therapy
* On methotrexate doses of 15 mg/week or more
* History of allergic reaction to ciprofloxacin, metronidazole, or aspirin
* Antibiotic use in the 30 days before chemotherapy start Note: Use of antibiotics intended for prophylaxis at the time of surgery is allowed
* Corrected QT interval (QTc) \>480 on baseline ECG
* Clinically significant hematuria, hematemesis, or hemoptysis of \>0.5 teaspoon (2.5 mL) of red blood, or other history of significant bleeding (eg, pulmonary hemorrhage) within 12 weeks before first dose of microbiome modulation therapy (significance determined by treating investigator)
* Diagnosed with a malabsorptive syndrome
* Inability to swallow tablets DRUG: Standard of Care Chemotherapy + Metronidazole, ciprofloxacin, aspirin
Colorectal Cancer, CRC
Colorectal Cancer, CRC
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Massey CTO GI Team - (masseygi@vcu.edu) |
A Study of Nivolumab-relatlimab Fixed-dose Combination Versus Regorafenib or TAS-102 in Participants With Later-lines of Metastatic Colorectal Cancer (RELATIVITY-123)
BMS Study Connect Contact Center www.BMSStudyConnect.com - Clinical.Trials@bms.com
NCT05328908
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Inclusion Criteria:
• Histological confirmed previously treated colorectal cancer with adenocarcinoma histology with metastatic or recurrent unresectable disease at study entry
• Participants must have:
• progressed during or within approximately 3 months following the last administration of approved standard therapies (at least 1, but not more than 4 prior lines of therapies), which must include a fluoropyrimidine, oxaliplatin, irinotecan, an anti-VEGF therapy, and anti-EGFR therapy (if KRAS wild-type), if available in the respective country, or;
• been intolerant to prior systemic chemotherapy regimens if there is documented evidence of clinically significant intolerance despite adequate supportive measures
• Must have sufficient tumor tissue & evaluable PD-L1 expression to meet the study requirements
• Must have measurable disease per RECIST v1.1. Participants with lesions in a previously irradiated field as the sole site of measurable disease will be permitted to enroll provided the lesion(s) have demonstrated clear progression and can be measured accurately
Exclusion Criteria:
• Prior treatment with either an immunotherapy or with regorafenib or with TAS-102
• Untreated central nervous system (CNS) metastases, participants are eligible if CNS metastases have been treated and participants have neurologically returned to baseline (except for residual signs or symptoms related to the CNS treatment)
• History of refractory hypertension not controlled with anti-hypertensive therapy, myocarditis (regardless of etiology), uncontrolled arrhythmias, acute coronary syndrome within 6 months prior to dosing, Class II congestive heart failure (as per the New York Heart Association Functional Classification), interstitial lung disease/pneumonitis or an active, known or suspected autoimmune disease
• Confirmed tumor microsatellite instable high/deficient mismatch repair (MSI-H/dMMR) status as per local standard testing; MSI/MMR test results from initial diagnosis are acceptable. Other protocol-defined inclusion/exclusion criteria apply
Drug: Nivolumab-relatlimab FDC, Drug: Regorafenib, Drug: TAS-102
Colorectal Neoplasms
Micro-satellite Stable (MSS) Metastatic Colorectal Cancer (mCRC), Relatlimab, Nivolumab, BMS-986213, Regorafenib, Stivarga, Lonsurf
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See this study on ClinicalTrials.gov
Show 156 locations
Study Locations
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| Location | Contacts |
|---|---|
| Astera Cancer Care East Brunswick, New Jersey | Phillip Reid, Site 0043 |
| Baptist Hospital of Miami Miami, Florida | Antonio Ucar, Site 0025 |
| Charleston Hematology Oncology Associates (CHOA) Charleston, South Carolina | David Ellison, Site 0008 |
| City of Hope Duarte, California | |
| Duke University Medical Center Durham, North Carolina | Michael Morse, Site 0009 |
| Eastern Connecticut Hematology and Oncology (ECHO) Norwich, Connecticut | Dennis Slater, Site 0117 |
| Fort Wayne Medical Oncology and Hematology Fort Wayne, Indiana | Sunil Babu, Site 0081 |
| Fox Chase Cancer Center Philadelphia, Pennsylvania | Namrata Vijayvergia, Site 0147 |
| Good Samaritan Hospital Corvallis, Oregon | David Draper, Site 0082 |
| Highlands Oncology Group - Springdale Springdale, Arkansas | J.Thaddeus Beck, Site 0044 |
| Local Institution - 0001 Lenexa, Kansas | Site 0001 |
| Local Institution - 0002 London, | |
| Local Institution - 0003 Oakland, California | Site 0003 |
| Local Institution - 0004 Sherbrooke, Quebec | Site 0004 |
| Local Institution - 0007 Mexico City, | Site 0007 |
| Local Institution - 0010 San Francisco, California | Site 0010 |
| Local Institution - 0014 Antwerpen, VAN | Site 0014 |
| Local Institution - 0015 Boston, Massachusetts | Site 0015 |
| Local Institution - 0016 Lima, LIM | Site 0016 |
| Local Institution - 0017 Atlanta, Georgia | Site 0017 |
| Local Institution - 0018 Seattle, Washington | Site 0018 |
| Local Institution - 0019 Atlanta, Georgia | Site 0019 |
| Local Institution - 0020 Badalona, Barcelona | Site 0020 |
| Local Institution - 0021 La Jolla, California | Site 0021 |
| Local Institution - 0022 Lima, LIM | |
| Local Institution - 0023 Napoli, | Site 0023 |
| Local Institution - 0024 Boston, Massachusetts | Site 0024 |
| Local Institution - 0026 New York, New York | Site 0026 |
| Local Institution - 0027 New Orleans, Louisiana | Site 0027 |
| Local Institution - 0028 Salt Lake City, Utah | Site 0028 |
| Local Institution - 0029 Pittsburgh, Pennsylvania | Site 0029 |
| Local Institution - 0030 Córdoba, VER | Site 0030 |
| Local Institution - 0033 Towson, Maryland | Site 0033 |
| Local Institution - 0034 Chicago, Illinois | Site 0034 |
| Local Institution - 0035 New York, New York | Site 0035 |
| Local Institution - 0036 Gent, | Site 0036 |
| Local Institution - 0037 Bruxelles, Pl-mz | Site 0037 |
| Local Institution - 0038 Leuven, | Site 0038 |
| Local Institution - 0039 Zuerich, | Site 0039 |
| Local Institution - 0040 Evanston, Illinois | Site 0040 |
| Local Institution - 0041 St.Gallen, HE | Site 0041 |
| Local Institution - 0045 Louisville, Kentucky | Site 0045 |
| Local Institution - 0046 Münster, | Site 0046 |
| Local Institution - 0050 Bedford Park, South Australia | Site 0050 |
| Local Institution - 0051 Sevilla, MZ | Site 0051 |
| Local Institution - 0052 Mainz, Rheinland-Pfalz | Site 0052 |
| Local Institution - 0053 Burlington, Ontario | Site 0053 |
| Local Institution - 0054 Tübingen, | Site 0054 |
| Local Institution - 0055 Lima, | Site 0055 |
| Local Institution - 0056 Berlin, | Site 0056 |
| Local Institution - 0057 Hannover, | Site 0057 |
| Local Institution - 0058 Chicago, Illinois | Site 0058 |
| Local Institution - 0059 Los Angeles, California | Site 0059 |
| Local Institution - 0060 Gainesville, Florida | Site 0060 |
| Local Institution - 0061 Utrecht, | Site 0061 |
| Local Institution - 0062 Detroit, Michigan | Site 0062 |
| Local Institution - 0063 Brno, JM | |
| Local Institution - 0064 Praha 5, Prague | Site 0064 |
| Local Institution - 0066 Massillon, Ohio | Site 0066 |
| Local Institution - 0067 Hackensack, New Jersey | Site 0067 |
| Local Institution - 0068 Seoul, Seoul-teukbyeolsi [Seoul] | Site 0068 |
| Local Institution - 0069 Seoul, Seoul-teukbyeolsi [Seoul] | Site 0069 |
| Local Institution - 0070 Seoul, Seoul-teukbyeolsi [Seoul] | Site 0070 |
| Local Institution - 0072 Madrid, | Site 0072 |
| Local Institution - 0073 Montreal, Quebec | Site 0073 |
| Local Institution - 0074 Montpellier, Languedoc-Roussillon | Site 0074 |
| Local Institution - 0075 Chengdu, Sichuan | Site 0075 |
| Local Institution - 0076 Villejuif, Val-de-Marne | Site 0076 |
| Local Institution - 0077 Paris, | Site 0077 |
| Local Institution - 0078 Monterrey, Nuevo León | Site 0078 |
| Local Institution - 0080 Providencia, RM | Site 0080 |
| Local Institution - 0083 Vienna, | Site 0083 |
| Local Institution - 0084 Klagenfurt, | Site 0084 |
| Local Institution - 0085 Sankt Pölten, | Site 0085 |
| Local Institution - 0086 Linz, | Site 0086 |
| Local Institution - 0087 Marseille, Bouches-du-Rhône | Site 0087 |
| Local Institution - 0088 Innsbruck, | Site 0088 |
| Local Institution - 0089 Pierre-Bénite, Rhône | Site 0089 |
| Local Institution - 0090 Bordeaux, Aquitaine | Site 0090 |
| Local Institution - 0091 Victoria, British Columbia | Site 0091 |
| Local Institution - 0092 Málaga, Málaga | Site 0092 |
| Local Institution - 0093 Salamanca, | Site 0093 |
| Local Institution - 0094 Evanston, Illinois | Site 0094 |
| Local Institution - 0098 Porto, | Site 0098 |
| Local Institution - 0099 Sherbrooke, Quebec | Site 0099 |
| Local Institution - 0100 Seoul, Seoul-teukbyeolsi [Seoul] | Site 0100 |
| Local Institution - 0101 Erlangen, Bavaria | Site 0101 |
| Local Institution - 0102 Madrid, | Site 0102 |
| Local Institution - 0103 Malaga, | Site 0103 |
| Local Institution - 0104 Atlanta, Georgia | Site 0104 |
| Local Institution - 0105 El Palmar, Murcia | Site 0105 |
| Local Institution - 0106 Santiago, Santiago Metropolitan | Site 0106 |
| Local Institution - 0107 Santiago, Santiago Metropolitan | Site 0107 |
| Local Institution - 0108 Santiago, Santiago Metropolitan | Site 0108 |
| Local Institution - 0109 Chile, Santiago Metropolitan | Site 0109 |
| Local Institution - 0110 Santiago, Santiago Metropolitan | Site 0110 |
| Local Institution - 0111 Córdoba, | Site 0111 |
| Local Institution - 0112 Buenos Aires, | Site 0112 |
| Local Institution - 0113 London, Greater London | Site 0113 |
| Local Institution - 0114 Busan, Pusan-Kwangyǒkshi | Site 0114 |
| Local Institution - 0115 Trieste, TS | Site 0115 |
| Local Institution - 0116 Deagu, Taegu-Kwangyǒkshi | Site 0116 |
| Local Institution - 0118 Seoul, | Site 0118 |
| Local Institution - 0119 Buenos Aires, | Site 0119 |
| Local Institution - 0120 Sagamihara, Kanagawa | Site 0120 |
| Local Institution - 0121 Shimotsuga, Tochigi | Site 0121 |
| Local Institution - 0122 Osaka, | Site 0122 |
| Local Institution - 0123 Huixquilucan, | Site 0123 |
| Local Institution - 0124 Nagasaki, | Site 0124 |
| Local Institution - 0125 Wangen I. Allgaeu, Baden-Wurttemberg | |
| Local Institution - 0126 Mexico City, Mexico City | Site 0126 |
| Local Institution - 0128 Mexico City, Mexico City | Site 0128 |
| Local Institution - 0129 Bogotá, Distrito Capital De Bogotá | Site 0129 |
| Local Institution - 0131 Busan, Pusan-Kwangyǒkshi | Site 0131 |
| Local Institution - 0133 Milano, MI | |
| Local Institution - 0134 Chongqing, Chongqing | Site 0134 |
| Local Institution - 0135 Stockholm, | Site 0135 |
| Local Institution - 0136 Buenos Aires, | |
| Local Institution - 0138 Bogota, | Site 0138 |
| Local Institution - 0139 Monterrey, Nuevo León | Site 0139 |
| Local Institution - 0141 Aguascalientes, AGU | Site 0141 |
| Local Institution - 0142 Münster, Northwest | Site 0142 |
| Local Institution - 0143 Seoul, Seoul-teukbyeolsi [Seoul] | Site 0143 |
| Local Institution - 0144 San Miguel, LIM | Site 0144 |
| Local Institution - 0146 Huaian, Jiangsu | Site 0146 |
| Local Institution - 0148 Katowice, | Site 0148 |
| Local Institution - 0149 Goyang-si, Kyǒnggi-do | Site 0149 |
| Local Institution - 0150 Bursa, | Site 0150 |
| Local Institution - 0151 Guangzhou, Guangdong | Site 0151 |
| Local Institution - 0152 Xian, SN | Site 0152 |
| Local Institution - 0153 Montreal, Quebec | Site 0153 |
| Local Institution - 0155 Ürümqi, Xinjiang | Site 0155 |
| Local Institution - 0156 Piura, PIU | Site 0156 |
| Local Institution - 0157 Valencia, Comunidad Valencia | Site 0157 |
| Local Institution - 0158 Changsha, Hunan | Site 0158 |
| Local Institution - 0159 Chengdu Shi, | Site 0159 |
| Local Institution - 0160 Budapest, Pest | Site 0160 |
| Local Institution - 0161 Nanning Shi, | Site 0161 |
| Local Institution - 0162 Monterrey, Nuevo Leon | Site 0162 |
| Local Institution - 0163 Córdoba, VER | |
| Massachusetts General Hospital, Boston, Massachusetts | Aparna Parikh, Site 0140 |
| Mayo Clinic in Arizona - Phoenix Phoenix, Arizona | |
| Northside Hospital - Atlanta Atlanta, Georgia | Ioana Bonta, Site 0031 |
| Perelman School of Medicine at the University of Pennsylvania Philadelphia, Pennsylvania | |
| Rush University Medical Center Chicago, Illinois | |
| Sanford Research Sioux Falls, South Dakota | Jonathan Bleeker, Site 0096 |
| St. Luke's Cancer Institute - Boise Boise, Idaho | Dan Zuckerman, Site 0071 |
| Tennessee Oncology Nashville, Tennessee | Meredith Pelster, Site 0127 |
| The Center for Cancer and Blood Disorders Fort Worth, Texas | Henry Xiong, Site 0097 |
| The James Cancer Hospital Columbus, Ohio | Pannaga Malalur, Site 0095 |
| The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive C Columbus, Ohio | Anne Noonan, Site 0079 |
| Thomas Jefferson University - Clinical Trials Office-Medical Oncology Philadelphia, Pennsylvania | Atrayee Basu-Mallick, Site 0130 |
| USC Norris Comprehensive Cancer Center Los Angeles, California | Heinz-Josef Lenz, Site 0012 |
| University of Michigan - Rogel Cancer Center Ann Arbor, Michigan | John Krauss, Site 0042 |
| University of Wisconsin-Madison - Wisconsin Institutes for Medical Research (WIMR) Madison, Wisconsin | Dustin Deming, Site 0005 |
| Virginia Commonwealth University Massey Cancer Center Richmond, Virginia | Khalid Matin, Site 0132 |
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy (OrigAMI-3)
Study Contact - Participate-In-This-Study1@its.jnj.com
NCT06750094
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:
* Have histologically or cytologically confirmed adenocarcinoma of the colon or rectum. Participants must have recurrent, unresectable or metastatic disease
* Determined to have kirsten rat sarcoma viral oncogene/neuroblastoma RAS viral oncogene homolog (KRAS/NRAS), G12, G13 and v-raf murine sarcoma viral oncogene homolog B (BRAF) V600X (X represents any single amino acid change from the original amino acid) wild type status by local and/or central next-generation sequencing (NGS) testing
* Must agree to the submission of fresh or archival tumor tissue post progression from the most recent therapy, if clinically feasible
* Have measurable disease according to response evaluation criteria in solid tumors (RECIST) version (v) 1.1
* Have an eastern cooperative oncology group (ECOG) performance status (PS) of 0 or 1
* Participant must have received 1 line of systemic therapy (fluoropyrimidine-based and oxaliplatin-based) for metastatic colorectal cancer (mCRC), with documented radiographic disease progression on or after this line of therapy. Participants can receive anti-VEGF as prior line of therapy
Exclusion Criteria:
* Has medical history of (noninfectious) interstitial lung disease (ILD) /pneumonitis/pulmonary fibrosis or has current ILD/pneumonitis/pulmonary fibrosis, or where suspected ILD/pneumonitis/pulmonary fibrosis cannot be ruled out by imaging at screening
* Has known allergies, hypersensitivity, or intolerance to excipients of any of the following: amivantamab, cetuximab or bevacizumab or any component of FOLFIRI
* Has a prior or concurrent second malignancy other than the disease under study or one whose natural history or treatment is likely to interfere with any study endpoints of safety or the efficacy of the study treatment(s)
* Participant with known mismatch repair deficiency (dMMR)/ high microsatellite instability (MSI-H) status who has not received immunotherapy treatments
* Participant with known human epidermal growth factor receptor 2 (HER2)- positive/amplified tumor
* Has prior exposure to irinotecan, any agents that target epidermal growth factor receptor (EGFR) or mesenchymal epithelial transition (MET) BIOLOGICAL: Amivantamab, BIOLOGICAL: Cetuximab, BIOLOGICAL: Bevacizumab, DRUG: 5-fluorouracil, DRUG: Leucovorin calcium/Levoleucovorin, DRUG: Irinotecan
Colorectal Neoplasms
I'm interested
Share via email
Show 224 locations
Study Locations
Hide all locations
| Location | Contacts |
|---|---|
| AZ Groeninge Kortrijk, | |
| AZ Maria Middelares Ghent, | |
| Actualidad Basada en la Investigación del Cáncer Guadalajara, | |
| Adana City Hospital Adana, | |
| AdventHealth Cancer Institute Orlando, Florida | |
| Aichi Cancer Center Nagoya, | |
| Alliance Cancer Specialists at Main Line Penn Wynne, Pennsylvania | |
| Ankara Bilkent Sehir Hastanesi Ankara, | |
| Antoni van Leeuwenhoek Amsterdam, | |
| Arizona Oncology Associates PC NAHOA Prescott, Arizona | |
| Asan Medical Center Seoul, | |
| Asian Institute Of Gastroenterology Hyderabad, | |
| Associacao Feminina de Educacao e Combate ao Cancer Hospital Santa Rita de Cassia Vitória, | |
| Assuta MC Tel Aviv, | |
| Astera Cancer Care East Brunswick, New Jersey | |
| Azienda Ospedaliero Universitaria Pisana Pisa, | |
| Azienda Sanitaria Universitaria Friuli Centrale ASU FC Udine, | |
| B P Poddar Hospital and Medical research Limited Kolkata, | |
| Bakirkoy Training and Research Hospital Istanbul, | |
| Banner MD Anderson Cancer Center Gilbert, Arizona | |
| Beijing Cancer Hospital Beijing, | |
| Beijing Friendship Hospital Capital Medical University Beijing, | |
| Bialostockie Centrum Onkologii im Marii Sklodowskiej Curie w Bialymstoku Bialystok, | |
| Birmingham Heartlands Hospital Birmingham, | |
| CBCC Global Research Bakersfield, California | |
| CHU de Poitiers Poitiers, | |
| COI Centro Oncologico Internacional Tijuana Tijuana, | |
| Cancer And Hematology Centers of Western Michigan PC Grand Rapids, Michigan | |
| Cancer and Blood Specialty Clinic Los Alamitos, California | |
| Castle Hill Hospital Hull, | |
| Centre Hospitalier Universitaire de Liege Domaine Universitaire du Sart Tilman Liège, | |
| Centro Oncologico Personalizado Cope S De R L De C V Mexico City, | |
| Centro Oncologico de Chihuahua Chihuahua City, | |
| Centrul Medical Unirea SRL Brasov, | |
| Chang Gung Memorial Hospital Kaohsiung City, | |
| Charite Universitatsmedizin Berlin Campus Virchow Klinikum Berlin, | |
| Chiang Mai University Chiang Mai, | |
| Chiba Cancer Center Chiba, Chiba | |
| Christian medical Vellore, | |
| Clinica Univ. de Navarra Pamplona, | |
| Clinica de Oncologie Sf Nectarie Craiova, | |
| Concord Hospital Concord, | |
| Cuidados Oncologicos Querétaro, | |
| Deenanath Mangeshkar Hospital and Research Centre Pune, | |
| Dr Abdurrahman Yurtaslan Oncology Training and Research Hospital Ankara, | |
| ETZ TweeSteden Tilburg, | |
| Eastern Connecticut Hematology & Oncology Assoc. Norwich, Connecticut | |
| Erasmus MC Rotterdam, | |
| Florida Cancer Specialists East West Palm Beach, Florida | |
| Florida Cancer Specialists North Region St. Petersburg, Florida | |
| Florida Cancer Specialists South Fort Myers, Florida | |
| Fox Chase Cancer Center Philadelphia, Pennsylvania | |
| Fred Hutchinson Cancer Research Center Seattle, Washington | |
| Fudan University Shanghai Cancer Center Shanghai, | |
| Fundacao Antonio Prudente A C Camargo Cancer Center São Paulo, | |
| Fundacao Faculdade Regional De Medicina S Jose Rio Preto Hospital De Base São José do Rio Preto, | |
| Fundacao Pio XII Barretos, | |
| Fundação Doutor Amaral Carvalho Jaú, | |
| Fundação Faculdade de Medicina - Instituto do Cancer do Estado de São Paulo São Paulo, | |
| Fundação Universidade de Caxias do Sul Caxias do Sul, | |
| Gansu Provincial Cancer Hospital Lanzhou, | |
| Ganzhou Cancer Hospital Ganzhou, | |
| Gazi University Hospital Ankara, | |
| Grady Memorial Hospital Delaware, Ohio | |
| Guangdong Provincial People's Hospital Guangzhou, | |
| Gulhane Egitim ve Arastirma Hastanesi Ankara, | |
| Hadassah Medical Center Jerusalem, | |
| Harbin Medical University Cancer Hospital Harbin, | |
| Hattiesburg Clinic Hattiesburg, Mississippi | |
| Health Pharma Queretaro SA de CV Querétaro, | |
| Henry Ford Hospital Detroit, Michigan | |
| Hopital Haut Leveque Pessac, | |
| Hosp Univ Vall D Hebron Barcelona, | |
| Hosp. Clinico Univ. de Valencia Valencia, | |
| Hosp. Gral. Univ. Gregorio Marañon Madrid, | |
| Hosp. Univ. 12 de Octubre Madrid, | |
| Hosp. Univ. Ramon Y Cajal Madrid, | |
| Hosp. Virgen Del Rocio Seville, | |
| Hosp. de La Santa Creu I Sant Pau Barcelona, | |
| Hospital Kuala Lumpur Kuala Lumpur, | |
| Hospital Nossa Senhora da Conceicao S A Porto Alegre, | |
| Hospital Pulau Pinang George Town, | |
| Hospital Raja Permaisuri Bainun Ipoh, | |
| Hospital Santa Izabel Santa Casa de Misericordia da Bahia Salvador, | |
| Hospital Umum Sarawak Kuching, | |
| Hospital Universitario Dr Jose Eleuterio Gonzalez Monterrey, | |
| Hubei Cancer Hospital Wuhan, | |
| Huizhou Central People's Hospital Huizhou, | |
| Hunan Cancer Hospital Changsha, | |
| Illinois CancerCare Peoria, Illinois | |
| Institut Jules Bordet Anderlecht, | |
| Institut Kanser Negara Clinical Research Center Putrajaya, | |
| Institut Sainte Catherine Avignon, | |
| Instytut Centrum Zdrowia Matki Polki Lodz, | |
| Ironwood Cancer and Research Center Chandler, Arizona | |
| Istituto Clinico Humanitas Rozzano, | |
| Istituto Dei Tumori Di Milano Milan, | |
| Istituto Oncologico Veneto - IRCCS Padua, | |
| Jolimont Haine-St-Paul, | |
| Kaohsiung Medical University Chung Ho Memorial Hospital Kaohsiung City, | |
| Karolinska Universitetssjukhuset Stockholm, | |
| Kindai University Hospital Sakai, | |
| Klinikum der Universitaet Muenchen Munich, | |
| Korea University Anam Hospital Seoul, | |
| Krankenhaus NorthWest Frankfurt am Main, | |
| Kyungpook National University Chilgok Hospital Daegu, | |
| Liaoning Cancer Hospital and Institute Shenyang, | |
| Linkou Chang Gung Memorial Hospital Taoyuan District, | |
| Los Angeles Cancer Network Glendale, California | |
| MD Anderson Cancer Center Houston, Texas | |
| Mahamana Pandit Madan Mohan Malviya Cancer Centre Varanasi, | |
| Markhot Ferenc Oktatokorhaz es Rendelointezet Eger, | |
| Marmara University Pendik Training Hospital Istanbul, | |
| Mary Bird Perkins Cancer Center Baton Rouge, Louisiana | |
| Meander Medisch Centrum Amersfoort, | |
| MedStar Franklin Square Medical Center Baltimore, Maryland | |
| Medical College of Wisconsin Milwaukee, Wisconsin | |
| Montefiore Einstein Comprehensive Cancer Center The Bronx, New York | |
| Mount Sinai Medical Center Campus Miami Beach, Florida | |
| Mount Vernon Cancer Centre Northwood, | |
| NYU Langone Medical Center NYU Hematology Associates New York, New York | |
| Narodowy Instytut Onkologii im Marii Sklodowskiej Curie Panstwowy Instytut Badawczy Warsaw, | |
| Narodowy Instytut Onkologii im Marii Sklodowskiej Curie Panstwowy Instytut BadawczyOddz w Gliwicach Gliwice, | |
| National Cancer Center Hospital Tokyo, | |
| National Cancer Center Hospital East Kashiwa, | |
| National Center for Tumor Diseases NCT Heidelberg, | |
| National Cheng Kung University Hospital Tainan, | |
| National Hospital Organization Osaka National Hospital Osaka, | |
| National Taiwan University Hospital Taipei, | |
| Nebraska Cancer Specialists Omaha, Nebraska | |
| Necmettin Erbakan University Meram Medical Faculty Konya, | |
| Neolife Medical Center Bucharest Bucharest, | |
| New York Cancer and Blood Specialists Shirley, New York | |
| Oncocenter Puebla City, | |
| Oregon Health and Science University Portland, Oregon | |
| Osaka International Cancer Institute Osaka, | |
| Pan American Center for Oncology Trials LLC San Juan, | |
| Pecsi Tudomanyegyetem Pécs, | |
| Peking University First Hospital Beijing, | |
| Pelican Impex SRL Oradea, | |
| Perlmutter Cancer Center at NYU Long Island Mineola, New York | |
| Piedmont Cancer Institute Atlanta, Georgia | |
| Ponderas Academic Hospital Bucharest, | |
| Prince of Wales Hospital Grimsby, | |
| Providence Medical Foundation Santa Rosa, California | |
| Providence Regional Cancer System Lacey, Washington | |
| Queen Elizabeth Hospital South Woodville, | |
| Queen Mary Hospital Hong Kong, | |
| Rabin Medical Center Petah Tikva, | |
| Radboud University Medical Center Nijmegen, | |
| Rajiv Gandhi Cancer Institute And Research Centre Delhi, | |
| Ramathibodi Hospital Bangkok, | |
| Rambam Medical Center Haifa, | |
| Rocky Mountain Cancer Centers Colorado Springs, Colorado | |
| Royal Marsden Hospital Sutton, | |
| SCRI Oncology Partners Nashville, Tennessee | |
| SPZOZ Ministerstwa Spraw Wewnetrznych z Warminsko Mazurskim Centrum Onkologii w Olsztynie Olsztyn, | |
| SPZOZ Opolskie Centrum Onkologii im. Prof. Tadeusza Koszarowskiego Opole, | |
| Safdarjung Hospital New Delhi, | |
| Sahlgrenska Universitetssjukhuset Gothenburg, | |
| Sakarya University Training and Research Hospital Sakarya, | |
| Samsung Medical Center Seoul, | |
| Scott and White Memorial Hospital Temple, Texas | |
| Seoul National University Hospital Seoul, | |
| Severance Hospital Yonsei University Health System Seoul, | |
| Sheba Medical Center Ramat Gan, | |
| Shizuoka Cancer Center Shizuoka, | |
| Siriraj Hospital Bangkok, | |
| Skanes universitetssjukhus Lund, | |
| Songklanagarind Hospital Songkhla, | |
| Spitalul Memorial Baneasa Bucharest, | |
| St Bartholomew's Hospital London, | |
| St James University Hospital Leeds, | |
| St. Bernard's Medical Center Jonesboro, Arkansas | |
| Sun Yat Sen University Cancer Center Guangzhou, | |
| Szegedi Tudomanyegyetem Szeged, | |
| Szpital Specjalistyczny w Brzozowie Podkarpacki Osrodek Onkologiczny im Ks B Markiewicza Brzozów, | |
| Södersjukhuset Stockholm, | |
| Taichung Veterans General Hospital Taichung, | |
| Taipei Veterans General Hospital Taipei, | |
| Tata Memorial Hospital Mumbai, | |
| Tel Aviv Sourasky Medical Center Tel Aviv, | |
| Tennessee Oncology Nashville, Tennessee | |
| Tennessee Oncology Nashville, Tennessee | |
| Texas Oncology - San Antonio San Antonio, Texas | |
| Texas Oncology DFW Dallas, Texas | |
| Texas Oncology West Texas Abilene, Texas | |
| The Cancer Institute Hospital of JFCR Tokyo, | |
| The Catholic University of Korea Seoul St Mary s Hospital Seoul, | |
| The First Affiliated Hospital of NanChang University Nanchang, | |
| The First Bethune Hospital of Jilin University Changchun, | |
| The Second Affiliated Hospital of Zhejiang University Hangzhou, | |
| The Sixth Affiliated Hospital Sun Yat sen University Guangzhou, | |
| The University of Osaka Hospital Suita, | |
| Thomas Jefferson University Philadelphia, Pennsylvania | |
| Tianjin Medical University Cancer Institute and Hospital Tianjin, | |
| Torrance Memorial Physicians Network Torrance, California | |
| UCLA Santa Monica, California | |
| USC Norris Comprehensive Cancer Center Los Angeles, California | |
| UT Health East Texas HOPE Cancer Center Tyler, Texas | |
| UT Southwestern Medical Center Dallas, Texas | |
| UZ Antwerpen Edegem, | |
| Universitair Ziekenhuis Leuven Leuven, | |
| University Cancer and Blood Center LLC Athens, Georgia | |
| University College Hospital London, | |
| University Hospital of Cleveland Cleveland, Ohio | |
| University Malaya Medical Centre Kuala Lumpur, | |
| University Of Pittsburgh Medical Center UPMC Hillman Cancer Center Pittsburgh, Pennsylvania | |
| University of Colorado Denver Anschultz Medical Campus Aurora, Colorado | |
| University of Michigan Rogel Cancer Center Ann Arbor, Michigan | |
| Universitätsmedizin der Johannes Gutenberg Universität Mainz Mainz, | |
| Uniwersyteckie Centrum Kliniczne Gdansk, | |
| Uppsala University Uppsala, | |
| VCU Massey Comprehensive Cancer Center Richmond, Virginia | |
| Vanderbilt University Medical Center Nashville, Tennessee | |
| Virginia Cancer Specialists Arlington, Virginia | |
| Warringal Private Hospital Heidelberg, | |
| Washington University School of Medicine St Louis, Missouri | |
| West China Hospital of Sichuan University Chengdu, | |
| Western Health Sunshine Hospital St Albans, | |
| Winship Cancer Institute Emory University Atlanta, Georgia | |
| Wojewodzki Szpital Specjalistyczny Biała Podlaska, | |
| Yitzhak Shamir Medical Center Beer Yaakov, | |
| Zhejiang Cancer Hospital Hangzhou, |
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer (OrigAMI-2)
Study Contact - Participate-In-This-Study1@its.jnj.com
NCT06662786
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:
* Have histologically or cytologically confirmed adenocarcinoma of the left-sided colorectal cancer. Participants must have unresectable or metastatic disease
* Determined to have Kirsten rat sarcoma viral oncogene (KRAS), neuroblastoma RAS viral oncogene homolog (NRAS), and v-raf murine sarcoma viral oncogene homolog B (BRAF) wild-type (WT) tumor by local and/or central testing (if available)
* Must agree to the submission of fresh tumor tissue
* Have measurable disease according to RECIST v1.1
* Have an eastern cooperative oncology group (ECOG) performance status (PS) of 0 or 1
Exclusion Criteria:
* Has medical history of (noninfectious) interstitial lung disease (ILD) /pneumonitis/pulmonary fibrosis or has current ILD/pneumonitis/pulmonary fibrosis, or where suspected ILD/pneumonitis/pulmonary fibrosis cannot be ruled out by imaging at screening
* Has known allergies, hypersensitivity, or intolerance to excipients of any of the following: (a) amivantamab or cetuximab, (b) any component of mFOLFOX6 and, (c) any component of FOLFIRI
* Has a prior or concurrent second malignancy other than the disease under study or one whose natural history or treatment is likely to interfere with any study endpoints of safety or the efficacy of the study treatment(s)
* Participant with known mismatch repair deficiency (dMMR)/ high microsatellite instability (MSI-H) status and human epidermal growth factor receptor 2 (HER2)-positive/amplified tumor
* Has prior exposure to any agents that target epidermal growth factor receptor (EGFR) or mesenchymal epithelial transition (MET) BIOLOGICAL: Amivantamab, BIOLOGICAL: Cetuximab, DRUG: 5-fluorouracil, DRUG: Leucovorin calcium/Levoleucovorin, DRUG: Oxaliplatin, DRUG: Irinotecan Hydrochloride
Colorectal Neoplasms
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Show 227 locations
Study Locations
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| Location | Contacts |
|---|---|
| AZ Groeninge Kortrijk, | |
| AZ Maria Middelares Ghent, | |
| Adana City Hospital Adana, | |
| Addenbrooke's Hospital Cambridge, | |
| AdventHealth Medical Group Oncology and Hematology at Orlando Orlando, Florida | |
| Aichi Cancer Center Nagoya, | |
| Ankara Bilkent Sehir Hastanesi Ankara, | |
| Antoni van Leeuwenhoek Amsterdam, | |
| Arthur J E Child Comprehensive Cancer Centre Calgary, Alberta | |
| Asan Medical Center Seoul, | |
| Asklepios Klinik Altona Hamburg, | |
| Associacao Feminina de Educacao e Combate ao Cancer Hospital Santa Rita de Cassia Vitória, | |
| Assuta MC Tel Aviv, | |
| Astera Cancer Care East Brunswick, New Jersey | |
| Azienda Ospedaliero Universitaria Pisana Pisa, | |
| B P Poddar Hospital and Medical research Limited Kolkata, | |
| Bakirkoy Training and Research Hospital Istanbul, | |
| Banner MD Anderson Cancer Center Gilbert, Arizona | |
| Baylor Scott and White Health Temple, Texas | |
| Beijing Cancer Hospital Beijing, | |
| Beijing Friendship Hospital Capital Medical University Beijing, | |
| Bialostockie Centrum Onkologii im Marii Sklodowskiej Curie w Bialymstoku Bialystok, | |
| Birmingham Heartlands Hospital Birmingham, | |
| CBCC Global Research Bakersfield, California | |
| CHU Nantes Nantes, | |
| CHU de Poitiers Poitiers, | |
| Cancer and Blood Specialty Clinic Los Alamitos, California | |
| Castle Hill Hospital Hull, | |
| Centre Hospitalier Universitaire de Liege Domaine Universitaire du Sart Tilman Liège, | |
| Centre de Recherche du CHUM Montreal, Quebec | |
| Centrum Onkologii - Instytut im. Marii Sklodowskiej-Curie Warsaw, | |
| Charite Universitatsmedizin Berlin Campus Virchow Klinikum Berlin, | |
| Chiba Cancer Center Chiba, Chiba | |
| Cleveland Clinic Cancer Center Fairview Hospital Moll Pavilion Cleveland, Ohio | |
| Cleveland Clinic Cancer Center Hillcrest Hospital Mayfield Heights, Ohio | |
| Cleveland Clinic Cancer Center Independence Family Health Center Independence, Ohio | |
| Cleveland Clinic Cancer Center Mansfield Mansfield, Ohio | |
| Cleveland Clinic Cancer Center South Pointe Hospital Warrensville Heights, Ohio | |
| Cleveland Clinic Cancer Center Strongsville Strongsville, Ohio | |
| Cleveland Clinic Cancer Centers Sandusky Sandusky, Ohio | |
| Clinica Univ. de Navarra Pamplona, | |
| Clinica de Hematologia e Oncologia Viver Ltda Santa Maria, | |
| Comprehensive Cancer Centers of Nevada Las Vegas, Nevada | |
| Deenanath Mangeshkar Hospital and Research Centre Pune, | |
| Dr Abdurrahman Yurtaslan Oncology Training and Research Hospital Ankara, | |
| Elisabeth-TweeSteden Ziekenhuis Tilburg, | |
| Erasmus MC Rotterdam, | |
| Essen University Hospital Essen, | |
| First Hospital of Shanxi Medical University Taiyuan, | |
| Florida Cancer Specialists East West Palm Beach, Florida | |
| Florida Cancer Specialists North Region St. Petersburg, Florida | |
| Florida Cancer Specialists South Fort Myers, Florida | |
| Fort Wayne Medical Oncology & Hematology Fort Wayne, Indiana | |
| Fox Chase Cancer Center Philadelphia, Pennsylvania | |
| Fred Hutchinson Cancer Research Center Seattle, Washington | |
| Fudan University Shanghai Cancer Center Shanghai, | |
| Fundacao Antonio Prudente A C Camargo Cancer Center São Paulo, | |
| Fundacao Faculdade Regional De Medicina S Jose Rio Preto Hospital De Base São José do Rio Preto, | |
| Fundacao Pio XII Barretos, | |
| Fundação Doutor Amaral Carvalho Jaú, | |
| Fundação Faculdade de Medicina - Instituto do Cancer do Estado de São Paulo São Paulo, | |
| Fundação Universidade de Caxias do Sul Caxias do Sul, | |
| Gazi University Hospital Ankara, | |
| Georgetown Univ Medical Center Lombardi Cancer Center Washington D.C., District of Columbia | |
| Grady Memorial Hospital Delaware, Ohio | |
| Guangdong Provincial People's Hospital Guangzhou, | |
| Gulhane Egitim ve Arastirma Hastanesi Ankara, | |
| Gustave Roussy Villejuif, | |
| Hadassah University Hospita Ein Kerem Jerusalem, | |
| Harbin Medical University Cancer Hospital Harbin, | |
| Hattiesburg Clinic Hattiesburg, Mississippi | |
| Henry Ford Hospital Detroit, Michigan | |
| Herbert Irving Comprehensive Cancer Center Columbia University Medical Center New York, New York | |
| Hopital Claude Huriez Lille, | |
| Hopital De Jolimont La Louvière, | |
| Hopital Haut Leveque Pessac, | |
| Hopital Prive Jean Mermoz Lyon, | |
| Hopital Saint Antoine Paris, | |
| Hosp Univ Vall D Hebron Barcelona, | |
| Hosp. Clinico Univ. de Valencia Valencia, | |
| Hosp. Gral. Univ. Gregorio Marañon Madrid, | |
| Hosp. Univ. 12 de Octubre Madrid, | |
| Hosp. Univ. Ramon Y Cajal Madrid, | |
| Hosp. Virgen Del Rocio Seville, | |
| Hosp. de La Santa Creu I Sant Pau Barcelona, | |
| Hospital Canselor Tuanku Muhriz UKM Cheras, | |
| Hospital Kuala Lumpur Kuala Lumpur, | |
| Hospital Nossa Senhora da Conceicao S A Porto Alegre, | |
| Hospital Pulau Pinang George Town, | |
| Hospital Raja Permaisuri Bainun Ipoh, | |
| Hospital Santa Izabel Santa Casa de Misericordia da Bahia Salvador, | |
| Hospital Umum Sarawak Kuching, | |
| Hubei Cancer Hospital Wuhan, | |
| Huizhou Central People's Hospital Huizhou, | |
| Hunan Cancer Hospital Changsha, | |
| Illinois CancerCare Peoria, Illinois | |
| Inova Schar Cancer Institute Dept of Fairfax Hospital Fairfax, Virginia | |
| Institut Jules Bordet Anderlecht, | |
| Institut Sainte Catherine Avignon, | |
| Institut du Cancer de Montpellier Montpellier, | |
| Instytut Centrum Zdrowia Matki Polki Lodz, | |
| Istituto Clinico Humanitas Rozzano, | |
| Istituto Dei Tumori Di Milano Milan, | |
| Istituto Oncologico Veneto - IRCCS Padua, | |
| Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori Meldola, | |
| Kaohsiung Chang Gung Memorial Hospital Kaohsiung City, | |
| Kaohsiung Medical University Chung Ho Memorial Hospital Kaohsiung City, | |
| Karolinska Universitetssjukhuset Stockholm, | |
| Klinikum der Universitaet Muenchen Munich, | |
| Krankenhaus NorthWest Frankfurt am Main, | |
| Kyungpook National University Chilgok Hospital Daegu, | |
| Liaoning Cancer Hospital and Institute Shenyang, | |
| Linkou Chang Gung Memorial Hospital Taoyuan District, | |
| Los Angeles Cancer Network Glendale, California | |
| MD Anderson Cancer Center Houston, Texas | |
| Mahamana Pandit Madan Mohan Malviya Cancer Centre Varanasi, | |
| Markhot Ferenc Oktatokorhaz es Rendelointezet Eger, | |
| Marmara University Pendik Training Hospital Istanbul, | |
| Meander Medisch Centrum Amersfoort, | |
| MedStar Franklin Square Medical Center Baltimore, Maryland | |
| Montefiore Einstein Comprehensive Cancer Center The Bronx, New York | |
| Mount Sinai New York, New York | |
| Mount Sinai West New York, New York | |
| Mount Vernon Cancer Centre Northwood, | |
| NYU Langone Medical Center NYU Hematology Associates New York, New York | |
| Narodowy Instytut Onkologii im Marii Sklodowskiej Curie Panstwowy Instytut BadawczyOddz w Gliwicach Gliwice, | |
| National Cancer Center Hospital Tokyo, | |
| National Cancer Center Hospital East Kashiwa, | |
| National Cancer Institute Putrajaya, | |
| National Center for Tumor Diseases NCT Heidelberg, | |
| National Cheng Kung University Hospital Tainan, | |
| National Hospital Organization Osaka National Hospital Osaka, | |
| National Taiwan University Hospital Taipei, | |
| Nebraska Cancer Specialists Midwest Cancer Center Omaha, Nebraska | |
| Necmettin Erbakan University Meram Medical Faculty Konya, | |
| New York Cancer and Blood Specialists Shirley, New York | |
| Ochsner Clinic Foundation New Orleans, Louisiana | |
| Osaka International Cancer Institute Osaka, | |
| Ottawa Hospital Ottawa, Ontario | |
| Pan American Center for Oncology Trials LLC San Juan, | |
| Pecsi Tudomanyegyetem Pécs, | |
| Peking University First Hospital Beijing, | |
| Peking University Shenzhen Hospital Shenzhen, | |
| Peking University Third Hospital Beijing, | |
| Perlmutter Cancer Center at NYU Long Island Mineola, New York | |
| Praxis fur interdisziplinare Onkologie & Hamatologie GbR Freiburg im Breisgau, | |
| Princess Margaret Cancer Centre Toronto, Ontario | |
| Providence Medical Foundation Santa Rosa, California | |
| Rabin Medical Center Petah Tikva, | |
| Radboud University Medical Center Nijmegen, | |
| Rajiv Gandhi Cancer Institute And Research Centre Delhi, | |
| Rambam Medical Center Haifa, | |
| Rocky Mountain Cancer Centers Colorado Springs, Colorado | |
| Royal Marsden Hospital (Sutton) Sutton, | |
| Rutgers Cancer Institute New Brunswick, New Jersey | |
| SCRI Oncology Partners Nashville, Tennessee | |
| SPZOZ Ministerstwa Spraw Wewnetrznych z Warminsko Mazurskim Centrum Onkologii w Olsztynie Olsztyn, | |
| SPZOZ Opolskie Centrum Onkologii im. Prof. Tadeusza Koszarowskiego Opole, | |
| START Midwest Grand Rapids, Michigan | |
| Sahlgrenska University Hospital Gothenburg, | |
| Sakarya University Training and Research Hospital Sakarya, | |
| Samsung Medical Center Seoul, | |
| Semmelweis Egyetem Budapest, | |
| Seoul National University Hospital Seoul, | |
| Severance Hospital Yonsei University Health System Seoul, | |
| Sheba Medical Center Ramat Gan, | |
| Shizuoka Cancer Center Shizuoka, | |
| Skanes universitetssjukhus Lund, | |
| Sociedade Beneficente Israelita Brasileira Hospital Albert Einstein São Paulo, | |
| St Bartholomew's Hospital London, | |
| St James University Hospital Leeds, | |
| St. Bernard's Medical Center Jonesboro, Arkansas | |
| Sun Yat Sen University Cancer Center Guangzhou, | |
| Swedish Cancer Institute Seattle, Washington | |
| Swedish Cancer Institute Seattle, Washington | |
| Swedish Cancer Institute Seattle, Washington | |
| Szegedi Tudomanyegyetem Szeged, | |
| Szpital Specjalistyczny w Brzozowie Podkarpacki Osrodek Onkologiczny im Ks B Markiewicza Brzozów, | |
| Södersjukhuset Stockholm, | |
| Tata Memorial Hospital Mumbai, | |
| Taussig Cancer Insititute Cleveland Clinic Cleveland, Ohio | |
| Tel Aviv Sourasky Medical Center Tel Aviv, | |
| Texas Oncology - San Antonio San Antonio, Texas | |
| Texas Oncology DFW Dallas, Texas | |
| Texas Oncology West Texas Abilene, Texas | |
| The Cancer Institute Hospital of JFCR Tokyo, | |
| The Catholic University of Korea Seoul St Marys Hospital Seoul, | |
| The First Affiliated Hospital Zhejiang University College of Medicine Hangzhou, | |
| The First Affiliated Hospital of NanChang University Nanchang, | |
| The First Bethune Hospital of Jilin University Changchun, | |
| The Second Affiliated Hospital of Zhejiang University College of Medicine Hangzhou, | |
| The Sixth Affiliated Hospital Sun Yat sen University Guangzhou, | |
| The University of Osaka Hospital Suita, | |
| Thomas Jefferson University Philadelphia, Pennsylvania | |
| Tianjin Medical University Cancer Institute and Hospital Tianjin, | |
| Torrance Memorial Physicians Network Torrance, California | |
| UCLA Santa Monica, California | |
| UMC Utrecht Utrecht, | |
| USC Norris Comprehensive Cancer Center Los Angeles, California | |
| UT Southwestern Dallas, Texas | |
| Universitaetsklinikum Carl Gustav Carus TU Dresden Dresden, | |
| Universitair Ziekenhuis Antwerpen Edegem, | |
| Universitair Ziekenhuis Leuven Leuven, | |
| University College Hospital London, | |
| University Hospitals Cleveland Medical Center Cleveland, Ohio | |
| University Malaya Medical Centre Kuala Lumpur, | |
| University Of Pittsburgh Medical Center UPMC Hillman Cancer Center Pittsburgh, Pennsylvania | |
| University of Michigan Ann Arbor, Michigan | |
| University of New Mexico Cancer Center Albuquerque, New Mexico | |
| University of North Carolina at Chapel Hill Chapel Hill, North Carolina | |
| Universitätsklinikum Ulm Ulm, | |
| Universitätsmedizin der Johannes Gutenberg Universität Mainz Mainz, | |
| Uniwersyteckie Centrum Kliniczne Gdansk, | |
| Uppsala University Uppsala, | |
| VA Ann Arbor Healthcare System Ann Arbor, Michigan | |
| VCU Massey Comprehensive Cancer Center Richmond, Virginia | |
| Virginia Cancer Specialists Arlington, Virginia | |
| Washington University School of Medicine St Louis, Missouri | |
| West China Hospital of Sichuan University Chengdu, | |
| Western General Hospital Edinburgh, | |
| William S. Middleton Memorial VA Madison, Wisconsin | |
| Winship Cancer Institute Emory University Atlanta, Georgia | |
| Wojewodzki Szpital Specjalistyczny Biała Podlaska, | |
| Wooster Milltown Specialty and Surgery Center Wooster, Ohio | |
| Yale University School of Medicine New Haven, Connecticut | |
| Yitzhak Shamir Medical Center Beer Yaakov, | |
| Zhejiang Cancer Hospital Hangzhou, |
Role of Circadian Factors in Inflammation and Colorectal Adenoma Risk
Shetty, Shreya - shettysa@vcu.edu
Burch, James
17947
HM20021857
Rectum, Colon
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| Location | Contacts |
|---|---|
| Virginia Commonwealth University Richmond, Virginia | Shetty, Shreya - (shettysa@vcu.edu) |
An Observational Research Study to Uncover Subtypes of Cancer Cachexia (LOTUS-CC)
Ashley Mack, MS - URCC_22063@urmc.rochester.edu
NCT06073431
Show full eligibility criteria
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Inclusion Criteria:
* Have a primary diagnosis of unresectable or stage IV 1) non-small cell lung cancer (NSCLC), 2) pancreatic adenocarcinoma, or 3) colorectal cancer
* Note: Patients do not need to have cachexia to be eligible
* Plan to start first-line systemic anti-cancer therapy (chemotherapy, immunotherapy, targeted therapy, interventional clinical trial) in the next 6 weeks or has started first-line systemic therapy in the previous 6 weeks.
* NOTE: Patients who received systemic anti-cancer therapy previously as part of adjuvant or neoadjuvant treatment and have since recurred are still eligible if such treatment ended \> 6 months prior to enrollment. Patients receiving concurrent radiation with systemic therapy or received local therapy alone (surgery, radiation therapy \[RT\]) prior to first line therapy remain eligible. Patients receiving maintenance treatment after first line therapy are not eligible
* Have an Eastern Cooperative Oncology Group (ECOG) performance status of 0, 1 or 2
* Be able to understand, speak and read English
* Be 18 years of age or older
Exclusion Criteria:
* Have contraindications to physical function assessments (30-second arm curl, Timed-Up-And-Go test, or 30-second chair-stand test) per the treating provider or their designee
* Have any planned major surgeries within the next 3 months
* Have received chemotherapy or surgery for separate primary cancer within the past 3 years other than early local staged non-melanoma skin cancer
* Be pregnant PROCEDURE: Biospecimen Collection, PROCEDURE: Computed Tomography, OTHER: Electronic Medical Record, OTHER: Medical Device Usage and Evaluation, OTHER: Physical Performance Testing, PROCEDURE: Positron Emission Tomography, OTHER: Survey Administration
Advanced Colorectal Carcinoma, Advanced Lung Non-Small Cell Carcinoma, Advanced Pancreatic Adenocarcinoma, Stage IV Colorectal Cancer AJCC v8, Stage IV Lung Cancer AJCC v8, Stage IV Pancreatic Cancer AJCC v8, Unresectable Colorectal Carcinoma, Unresectable Lung Non-Small Cell Carcinoma, Unresectable Pancreatic Adenocarcinoma
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Study Locations
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| Location | Contacts |
|---|---|
| AMG Crystal Lake - Oncology Crystal Lake, Illinois | Site Public Contact - (advocateresearch@advocate.com) |
| AMG Libertyville - Oncology Libertyville, Illinois | Site Public Contact - (advocateresearch@advocatehealth.com) |
| Abbott-Northwestern Hospital Minneapolis, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Advocate Christ Medical Center Oak Lawn, Illinois | |
| Advocate Good Samaritan Hospital Downers Grove, Illinois | Site Public Contact - (Barbara.barhamand@advocatehealth.com) |
| Advocate Good Shepherd Hospital Barrington, Illinois | |
| Advocate Illinois Masonic Medical Center Chicago, Illinois | |
| Advocate Lutheran General Hospital Park Ridge, Illinois | |
| Advocate Outpatient Center - Oak Lawn Oak Lawn, Illinois | Site Public Contact - (ncorp@aah.org) |
| Advocate Sherman Hospital Elgin, Illinois | |
| Advocate South Suburban Hospital Hazel Crest, Illinois | |
| Armes Family Cancer Center Findlay, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Aurora Bay Area Medical Group-Marinette Marinette, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora BayCare Medical Center Green Bay, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Cancer Care-Grafton Grafton, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Cancer Care-Kenosha South Kenosha, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Cancer Care-Milwaukee Milwaukee, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Cancer Care-Milwaukee West Wauwatosa, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Cancer Care-Racine Racine, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Cancer Care-Southern Lakes VLCC Burlington, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Health Care Germantown Health Center Germantown, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Health Center - Greenfield Greenfield, Wisconsin | Site Public Contact - (ncorp@aah.org) |
| Aurora Medical Center in Summit Summit, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Saint Luke's Medical Center Milwaukee, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Saint Luke's South Shore Cudahy, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora Sinai Medical Center Milwaukee, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Aurora West Allis Medical Center West Allis, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| BJC Outpatient Center at Sunset Hills Sunset Hills, Missouri | |
| Beebe Health Campus Rehoboth Beach, Delaware | Site Public Contact - (research@beebehealthcare.org) |
| Beebe South Coastal Health Campus Millville, Delaware | Site Public Contact - (research@beebehealthcare.org) |
| Blanchard Valley Hospital Findlay, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Boulder Community Foothills Hospital Boulder, Colorado | Site Public Contact - (info@westernstatesncorp.org) |
| Bronson Methodist Hospital Kalamazoo, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
| Cancer Care Center of O'Fallon O'Fallon, Illinois | Site Public Contact - (morganthaler.jodi@mhsil.com) |
| Cancer Care Specialists of Illinois - Decatur Decatur, Illinois | Site Public Contact - (morganthaler.jodi@mhsil.com) |
| Cancer Center of Western Wisconsin New Richmond, Wisconsin | Site Public Contact - (mmcorc@healthpartners.com) |
| Carle BroMenn Medical Center Normal, Illinois | Site Public Contact - (Research@Carle.com) |
| Carle Cancer Center Urbana, Illinois | Site Public Contact - (Research@carle.com) |
| Carle at The Riverfront Danville, Illinois | Site Public Contact - (Research@Carle.com) |
| Centralia Oncology Clinic Centralia, Illinois | Site Public Contact - (morganthaler.jodi@mhsil.com) |
| Christiana Care - Union Hospital Elkton, Maryland | Site Public Contact - (frank.crum@christianacare.org) |
| Christiana Care Health System-Christiana Hospital Newark, Delaware | Site Public Contact - (lbarone@christianacare.org) |
| Christiana Care Health System-Wilmington Hospital Wilmington, Delaware | Site Public Contact - (lbarone@christianacare.org) |
| Colorado Blood Cancer Institute Denver, Colorado | Site Public Contact - (info@westernstatesncorp.org) |
| Comprehensive Cancer Centers of Nevada - Central Valley Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Comprehensive Cancer Centers of Nevada - Henderson Henderson, Nevada | Site Public Contact - (research@sncrf.org) |
| Comprehensive Cancer Centers of Nevada - Northwest Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Comprehensive Cancer Centers of Nevada - Town Center Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Comprehensive Cancer Centers of Nevada-Southeast Henderson Henderson, Nevada | Site Public Contact - (research@sncrf.org) |
| Comprehensive Cancer Centers of Nevada-Summerlin Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Condell Memorial Hospital Libertyville, Illinois | Site Public Contact - (advocateresearch@advocatehealth.com) |
| Corewell Health Grand Rapids Hospitals - Butterworth Hospital Grand Rapids, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
| Crossroads Cancer Center Effingham, Illinois | Site Public Contact - (morganthaler.jodi@mhsil.com) |
| Dayton Physician LLC - Englewood Dayton, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Dayton Physicians LLC - Troy Troy, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Dayton Physicians LLC-Atrium Franklin, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Decatur Memorial Hospital Decatur, Illinois | Site Public Contact - (morganthaler.jodi@mhsil.com) |
| Dickinson County Healthcare System Iron Mountain, Michigan | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Fairview Clinics and Surgery Center Maple Grove Maple Grove, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Fairview Lakes Medical Center Wyoming, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Fairview Northland Medical Center Princeton, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Fairview Southdale Hospital Edina, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Gibbs Cancer Center-Gaffney Gaffney, South Carolina | Site Public Contact - (kmertz-rivera@gibbscc.org) |
| Gibbs Cancer Center-Pelham Greer, South Carolina | Site Public Contact - (kmertz-rivera@gibbscc.org) |
| Greater Dayton Cancer Center Kettering, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| HSHS Sacred Heart Hospital Eau Claire, Wisconsin | |
| HSHS Saint Elizabeth's Hospital O'Fallon, Illinois | Site Public Contact - (morganthaler.jodi@mhsil.com) |
| Hawaii Cancer Care - Westridge ‘Aiea, Hawaii | Site Public Contact - (info@hawaiicancercare.com) |
| Hawaii Cancer Care Inc - Waterfront Plaza Honolulu, Hawaii | Site Public Contact - (i.webster@hawaiicancercare.com) |
| Helen F Graham Cancer Center Newark, Delaware | Site Public Contact - (lbarone@christianacare.org) |
| Hennepin County Medical Center Minneapolis, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Illinois CancerCare - Washington Washington, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Bloomington Bloomington, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Canton Canton, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Carthage Carthage, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Dixon Dixon, Illinois | |
| Illinois CancerCare-Eureka Eureka, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Galesburg Galesburg, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Kewanee Clinic Kewanee, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Macomb Macomb, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Ottawa Clinic Ottawa, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Pekin Pekin, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Peoria Peoria, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Peru Peru, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Princeton Princeton, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Indu and Raj Soin Medical Center Beavercreek, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| John B Amos Cancer Center Columbus, Georgia | Site Public Contact - (cdean@iacthealth.com) |
| Kapiolani Medical Center for Women and Children Honolulu, Hawaii | |
| Kettering Medical Center Kettering, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Lakeview Hospital Stillwater, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Lewis Cancer and Research Pavilion at Saint Joseph's/Candler Savannah, Georgia | Site Public Contact - (underberga@sjchs.org) |
| Marietta Memorial Hospital Marietta, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Marshfield Medical Center - Minocqua Minocqua, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center - Weston Weston, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center-EC Cancer Center Eau Claire, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center-Marshfield Marshfield, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center-Rice Lake Rice Lake, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center-River Region at Stevens Point Stevens Point, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| MedStar Georgetown University Hospital Washington D.C., District of Columbia | |
| Medical Oncology Hematology Consultants PA Newark, Delaware | Site Public Contact - (lbarone@christianacare.org) |
| Memorial Health University Medical Center Savannah, Georgia | Site Public Contact - (Lorraine.OHara@hcahealthcare.com) |
| Memorial Hospital of Carbondale Carbondale, Illinois | Site Public Contact - (clinical.research@sih.net) |
| Mercy Hospital Coon Rapids, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Mercy Hospital Fort Smith Fort Smith, Arkansas | |
| Mercy Hospital South St Louis, Missouri | Site Public Contact - (Danielle.Werle@mercy.net) |
| Mercy Hospital Springfield Springfield, Missouri | |
| Methodist Medical Center of Illinois Peoria, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Minnesota Oncology - Burnsville Burnsville, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Minnesota Oncology Hematology PA-Maplewood Maplewood, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Minnesota Oncology Hematology PA-Woodbury Woodbury, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Missouri Baptist Medical Center St Louis, Missouri | |
| Missouri Baptist Sullivan Hospital Sullivan, Missouri | |
| Monticello Cancer Center Monticello, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| New Ulm Medical Center New Ulm, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Northeast Georgia Medical Center Braselton Braselton, Georgia | Site Public Contact - (cancerpatient.navigator@nghs.com) |
| Northeast Georgia Medical Center-Gainesville Gainesville, Georgia | Site Public Contact - (cancerpatient.navigator@nghs.com) |
| Northside Hospital Atlanta, Georgia | Site Public Contact - (ClinicalTrials@northside.com) |
| Northside Hospital - Duluth Duluth, Georgia | Site Public Contact - (Clinical.trials@northside.com) |
| Northside Hospital - Gwinnett Lawrenceville, Georgia | Site Public Contact - (Clinical.trials@northside.com) |
| Northwell Health/Center for Advanced Medicine Lake Success, New York | |
| Oncology Hematology Care Inc-Kenwood Cincinnati, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| OptumCare Cancer Care at Charleston Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| OptumCare Cancer Care at Fort Apache Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| OptumCare Cancer Care at MountainView Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| OptumCare Cancer Care at Seven Hills Henderson, Nevada | Site Public Contact - (research@sncrf.org) |
| Pali Momi Medical Center ‘Aiea, Hawaii | |
| Park Nicollet Clinic - Saint Louis Park Saint Louis Park, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Parkland Health Center - Farmington Farmington, Missouri | |
| PeaceHealth Saint John Medical Center Longview, Washington | Site Public Contact - (kmakin-bond@peacehealth.org) |
| PeaceHealth Saint Joseph Medical Center Bellingham, Washington | |
| PeaceHealth Southwest Medical Center Vancouver, Washington | Site Public Contact - (kmakin-bond@peacehealth.org) |
| Prisma Health Cancer Institute - Butternut Greenville, South Carolina | |
| Providence Newberg Medical Center Newberg, Oregon | Site Public Contact - (CanRsrchStudies@providence.org) |
| Providence Portland Medical Center Portland, Oregon | Site Public Contact - (CanRsrchStudies@providence.org) |
| Providence Saint Vincent Medical Center Portland, Oregon | Site Public Contact - (CanRsrchStudies@providence.org) |
| Providence Willamette Falls Medical Center Oregon City, Oregon | Site Public Contact - (CanRsrchStudies@providence.org) |
| Queen's Cancer Cenrer - POB I Honolulu, Hawaii | |
| Queen's Cancer Center - Kuakini Honolulu, Hawaii | |
| Queen's Cancer Center - Pearlridge ‘Aiea, Hawaii | |
| Queen's Medical Center Honolulu, Hawaii | |
| Regions Hospital Saint Paul, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Reid Health Richmond, Indiana | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Rice Memorial Hospital Willmar, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Ridgeview Medical Center Waconia, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Rocky Mountain Cancer Centers - Centennial Centennial, Colorado | Site Public Contact - (info@westernstatesncorp.org) |
| Rocky Mountain Cancer Centers - Swedish Englewood, Colorado | Site Public Contact - (info@westernstatesncorp.org) |
| Rocky Mountain Cancer Centers-Aurora Aurora, Colorado | Site Public Contact - (info@westernstatesncorp.org) |
| Rocky Mountain Cancer Centers-Boulder Boulder, Colorado | Site Public Contact - (info@westernstatesncorp.org) |
| Rocky Mountain Cancer Centers-Lakewood Lakewood, Colorado | Site Public Contact - (info@westernstatesncorp.org) |
| Rocky Mountain Cancer Centers-Littleton Littleton, Colorado | Site Public Contact - (info@westernstatesncorp.org) |
| Rocky Mountain Cancer Centers-Midtown Denver, Colorado | Site Public Contact - (info@westernstatesncorp.org) |
| Rocky Mountain Cancer Centers-Rose Denver, Colorado | Site Public Contact - (info@westernstatesncorp.org) |
| Rocky Mountain Cancer Centers-Sky Ridge Lone Tree, Colorado | Site Public Contact - (info@westernstatesncorp.org) |
| Rocky Mountain Cancer Centers-Thornton Thornton, Colorado | Site Public Contact - (info@westernstatesncorp.org) |
| SIH Cancer Institute Carterville, Illinois | Site Public Contact - (clinical.research@sih.net) |
| SMC Center for Hematology Oncology Union Union, South Carolina | Site Public Contact - (kmertz-rivera@gibbscc.org) |
| Saint Elizabeth Boardman Hospital Boardman, Ohio | |
| Saint Elizabeth Youngstown Hospital Youngstown, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| Saint Francis Regional Medical Center Shakopee, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Saint John's Hospital - Healtheast Maplewood, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Saint Joseph Warren Hospital Warren, Ohio | |
| Saint Joseph's/Candler - Bluffton Campus Bluffton, South Carolina | Site Public Contact - (underberga@sjchs.org) |
| Saint Vincent Hospital Cancer Center Green Bay Green Bay, Wisconsin | Site Public Contact - (WI_research_admin@hshs.org) |
| Saint Vincent Hospital Cancer Center at Saint Mary's Green Bay, Wisconsin | Site Public Contact - (wi_research_admin@hshs.org) |
| Saint Vincent Hospital Cancer Center at Sturgeon Bay Sturgeon Bay, Wisconsin | Site Public Contact - (wi_research_admin@hshs.org) |
| Sainte Genevieve County Memorial Hospital Sainte Genevieve, Missouri | |
| Shenandoah Oncology PC Winchester, Virginia | Site Public Contact - (William.Houck@usoncology.com) |
| South Carolina Cancer Specialists PC Hilton Head Island, South Carolina | Site Public Contact - (underberga@sjchs.org) |
| South Georgia Medical Center/Pearlman Cancer Center Valdosta, Georgia | Site Public Contact - (maryann.heddon@sgmc.org) |
| Southern Illinois University School of Medicine Springfield, Illinois | |
| Spartanburg Medical Center Spartanburg, South Carolina | Site Public Contact - (kmertz-rivera@gibbscc.org) |
| Springfield Clinic Springfield, Illinois | |
| Springfield Memorial Hospital Springfield, Illinois | Site Public Contact - (pallante.beth@mhsil.com) |
| Straub Clinic and Hospital Honolulu, Hawaii | |
| Strecker Cancer Center-Belpre Belpre, Ohio | Site Public Contact - (Jeffh@columbusccop.org) |
| Summerlin Hospital Medical Center Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| The Longstreet Clinic - Gainesville Gainesville, Georgia | |
| The Melanoma and Skin Cancer Institute Englewood, Colorado | Site Public Contact - (ryan.weight@theskincancerinstitute.com) |
| The Queen's Medical Center - West Oahu ‘Ewa Beach, Hawaii | Site Public Contact - (rohta@queens.org) |
| The Women's Imaging Center Denver, Colorado | Site Public Contact - (info@westernstatesncorp.org) |
| ThedaCare Regional Cancer Center Appleton, Wisconsin | Site Public Contact - (ResearchDept@thedacare.org) |
| Tift Regional Medical Center Tifton, Georgia | |
| Trinity Health Grand Rapids Hospital Grand Rapids, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
| United Hospital Saint Paul, Minnesota | Site Public Contact - (mmcorc@healthpartners.com) |
| Urology Specialists of Nevada - Green Valley Henderson, Nevada | Site Public Contact - (research@sncrf.org) |
| Urology Specialists of Nevada - Northwest Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Urology Specialists of Nevada - Southwest Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| VCU Community Memorial Health Center South Hill, Virginia | Site Public Contact - (nemer.elmouallem@vcuhealth.org) |
| Valley Medical Center Renton, Washington | Site Public Contact - (research@valleymed.org) |
| Valley Radiation Oncology Peru, Illinois | |
| Vince Lombardi Cancer Clinic - Oshkosh Oshkosh, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Vince Lombardi Cancer Clinic-Sheboygan Sheboygan, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Vince Lombardi Cancer Clinic-Two Rivers Two Rivers, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Wayne Hospital Greenville, Ohio | Site Public Contact - (clinical.trials@daytonncorp.org) |
| West Michigan Cancer Center Kalamazoo, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics (COSMIC)
Karen Craver - NCORP@wfusm.edu
NCT06418204
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Inclusion Criteria:
* Adults aged 18 years or older with one of the following newly diagnosed cancers: breast cancer, colorectal cancer, melanoma, non-Hodgkin lymphoma, or non-small cell lung cancer (e.g. adenocarcinoma, squamous cell carcinoma, large cell carcinoma, adenosquamous cell carcinoma, and not otherwise specified).
* Planned treatment with systemic chemotherapy (single or multi-agent, includes targeted therapy) and/or immune checkpoint inhibitor therapy (targeting PD-1, PD-L1 or CTLA-4). If unable to engage participant before treatment starts, enrollment is allowed up to the start of Cycle 2 treatment.
* Participants must be able to comprehend English or Spanish (for survey completion).
* Participants must have a working email address and be must be willing to complete surveys online. This can be completed at home, in the clinic or other location.
* Completion of the confidential Self-Reported Screening Survey and receipt of a screening result - eligible for enrollment.
* Participant must reside in the United States, officially determined per patient report on Self-reported Screening Survey
* In the treating provider's opinion, the participant should have a life expectancy of \>=6 months. Participants in hospice are not eligible.
Optional Sub-study (available at select sites only):
* Must be willing to participate in both the main study and the sub-study at the Wake Forest University Comprehensive Cancer Center (WF CCC) and Virginia Commonwealth University (VCU).
* Must be receiving treatment at the WF CCC and VCU.
* Must be diagnosed with non-small cell lung cancer.
* Must be planning to receive paclitaxel as part of their chemotherapy in conjunction with Immune Checkpoint Inhibitor (ICIs) PD-1, PD-L1 or CTLA-4.
Exclusion Criteria:
* Currently enrolled in an interventional supportive treatment trial to manage cancer symptoms.
* Participants with known pregnancy.
* Participant received systemic therapy treatment for prior cancer(s) including chemotherapy, immunotherapy, targeted therapy, and hormonal therapy.
* Participants enrolled in hospice.
Optional Substudy (available at select sites only):
* Participants with chronic or ongoing steroid or immunomodulatory agents (i.e., prednisone, dexamethasone, etanercept, infliximab, etc.). The use of glucocorticoids as pre-medications for chemotherapy treatment is allowed.
* Participants with a history of HIV, hepatitis B or hepatitis C. OTHER: Non-interventional Study
Breast Carcinoma, Colorectal Carcinoma, Lung Non-Small Cell Carcinoma, Melanoma, Non-Hodgkin Lymphoma
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Show 447 locations
Study Locations
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| Location | Contacts |
|---|---|
| AMG Crystal Lake - Oncology Crystal Lake, Illinois | - (advocateresearch@advocate.com) |
| AMG Libertyville - Oncology Libertyville, Illinois | - (advocateresearch@advocatehealth.com) |
| Abbott-Northwestern Hospital Minneapolis, Minnesota | - (mmcorc@healthpartners.com) |
| Adams Cancer Center Gettysburg, Pennsylvania | |
| Advocate Christ Medical Center Oak Lawn, Illinois | |
| Advocate Good Samaritan Hospital Downers Grove, Illinois | - (Barbara.barhamand@advocatehealth.com) |
| Advocate Good Shepherd Hospital Barrington, Illinois | |
| Advocate High Tech Medical Park Palos Heights, Illinois | - (ncorp@aah.org) |
| Advocate Illinois Masonic Medical Center Chicago, Illinois | |
| Advocate Lutheran General Hospital Park Ridge, Illinois | |
| Advocate Outpatient Center - Aurora Aurora, Illinois | - (ncorp@aah.org) |
| Advocate Outpatient Center - Oak Lawn Oak Lawn, Illinois | - (ncorp@aah.org) |
| Advocate Sherman Hospital Elgin, Illinois | |
| Advocate South Suburban Hospital Hazel Crest, Illinois | |
| AnMed Health Cancer Center Anderson, South Carolina | - (rhonda.ballew@anmedhealth.org) |
| Armes Family Cancer Center Findlay, Ohio | - (clinical.trials@daytonncorp.org) |
| Ascension All Saints Hospital Racine, Wisconsin | - (AWRI.Inquiry@Ascension.org) |
| Ascension Calumet Hospital Chilton, Wisconsin | - (AWRI.inquiry@ascension.org) |
| Ascension Columbia Saint Mary's Hospital - Milwaukee Milwaukee, Wisconsin | - (AWRI.Inquiry@Ascension.org) |
| Ascension Columbia Saint Mary's Hospital Ozaukee Mequon, Wisconsin | - (AWRI.Inquiry@Ascension.org) |
| Ascension Medical Group Southeast Wisconsin - Mayfair Road Wauwatosa, Wisconsin | - (AWRI.Inquiry@Ascension.org) |
| Ascension Mercy Hospital Oshkosh, Wisconsin | - (AWRI.inquiry@ascension.org) |
| Ascension Saint Elizabeth Hospital Appleton, Wisconsin | - (AWRI.inquiry@ascension.org) |
| Ascension Saint Francis - Reiman Cancer Center Franklin, Wisconsin | - (AWRI.Inquiry@Ascension.org) |
| Ascension Southeast Wisconsin Hospital - Elmbrook Campus Brookfield, Wisconsin | - (AWRI.Inquiry@Ascension.org) |
| Aspirus Cancer Care - James Beck Cancer Center Rhinelander, Wisconsin | - (Beth.Knetter@aspirus.org) |
| Aspirus Cancer Care - Stevens Point Stevens Point, Wisconsin | - (Beth.Knetter@aspirus.org) |
| Aspirus Cancer Care - Wisconsin Rapids Wisconsin Rapids, Wisconsin | |
| Aspirus Langlade Hospital Antigo, Wisconsin | - (Juli.Alford@aspirus.org) |
| Aspirus Medford Hospital Medford, Wisconsin | - (Beth.Knetter@aspirus.org) |
| Aspirus Regional Cancer Center Wausau, Wisconsin | |
| Atrium Health Cabarrus/LCI-Concord Concord, North Carolina | |
| Atrium Health Cleveland/LCI-Cleveland Shelby, North Carolina | |
| Atrium Health Navicent Macon, Georgia | - (andrew.weatherall@atriumhealth.org) |
| Atrium Health Pineville/LCI-Pineville Charlotte, North Carolina | |
| Atrium Health Stanly/LCI-Albemarle Albemarle, North Carolina | |
| Atrium Health Union/LCI-Union Monroe, North Carolina | |
| Atrium Health University City/LCI-University Charlotte, North Carolina | |
| Augusta Health Center for Cancer and Blood Disorders Fishersville, Virginia | |
| Aurora Bay Area Medical Group-Marinette Marinette, Wisconsin | - (ncorp@aurora.org) |
| Aurora BayCare Medical Center Green Bay, Wisconsin | - (ncorp@aurora.org) |
| Aurora Cancer Care-Grafton Grafton, Wisconsin | - (ncorp@aurora.org) |
| Aurora Cancer Care-Kenosha South Kenosha, Wisconsin | - (ncorp@aurora.org) |
| Aurora Cancer Care-Milwaukee Milwaukee, Wisconsin | - (ncorp@aurora.org) |
| Aurora Cancer Care-Milwaukee West Wauwatosa, Wisconsin | - (ncorp@aurora.org) |
| Aurora Cancer Care-Racine Racine, Wisconsin | - (ncorp@aurora.org) |
| Aurora Cancer Care-Southern Lakes VLCC Burlington, Wisconsin | - (ncorp@aurora.org) |
| Aurora Health Care Germantown Health Center Germantown, Wisconsin | - (ncorp@aurora.org) |
| Aurora Medical Center in Summit Summit, Wisconsin | - (ncorp@aurora.org) |
| Aurora Saint Luke's Medical Center Milwaukee, Wisconsin | - (ncorp@aurora.org) |
| Aurora Saint Luke's South Shore Cudahy, Wisconsin | - (ncorp@aurora.org) |
| Aurora Sinai Medical Center Milwaukee, Wisconsin | - (ncorp@aurora.org) |
| Aurora West Allis Medical Center West Allis, Wisconsin | - (ncorp@aurora.org) |
| BJC Outpatient Center at Sunset Hills Sunset Hills, Missouri | |
| Baptist Cancer Center-Grenada Grenada, Mississippi | - (BCCclintrials@bmhcc.org) |
| Baptist Memorial Hospital and Cancer Center-Collierville Collierville, Tennessee | - (BCCclintrials@bmhcc.org) |
| Baptist Memorial Hospital and Cancer Center-Desoto Southhaven, Mississippi | - (BCCclintrials@bmhcc.org) |
| Baptist Memorial Hospital and Cancer Center-Golden Triangle Columbus, Mississippi | - (BCCclintrials@bmhcc.org) |
| Baptist Memorial Hospital and Cancer Center-Memphis Memphis, Tennessee | - (BCCclintrials@bmhcc.org) |
| Baptist Memorial Hospital and Cancer Center-Oxford Oxford, Mississippi | - (BCCclintrials@bmhcc.org) |
| Baptist Memorial Hospital and Cancer Center-Union County New Albany, Mississippi | - (BCCclintrials@bmhcc.org) |
| Baptist Memorial Hospital for Women Memphis, Tennessee | - (BCCclintrials@bmhcc.org) |
| Beaufort Memorial Hospital Beaufort, South Carolina | - (kwade@bmhsc.org) |
| Beebe Health Campus Rehoboth Beach, Delaware | - (research@beebehealthcare.org) |
| Beebe South Coastal Health Campus Millville, Delaware | - (research@beebehealthcare.org) |
| Benefis Sletten Cancer Institute Great Falls, Montana | - (mccinfo@mtcancer.org) |
| Billings Clinic Cancer Center Billings, Montana | - (research@billingsclinic.org) |
| Blanchard Valley Hospital Findlay, Ohio | - (clinical.trials@daytonncorp.org) |
| Bozeman Health Deaconess Hospital Bozeman, Montana | - (mccinfo@mtcancer.org) |
| Broadlawns Medical Center Des Moines, Iowa | |
| Bronson Battle Creek Battle Creek, Michigan | - (crcwm-regulatory@crcwm.org) |
| CHI Health Good Samaritan Kearney, Nebraska | - (ResearchInstituteInquiries@CommonSpirit.org) |
| Cancer Care Center of O'Fallon O'Fallon, Illinois | - (morganthaler.jodi@mhsil.com) |
| Cancer Care Specialists of Illinois - Decatur Decatur, Illinois | - (morganthaler.jodi@mhsil.com) |
| Cancer Center at Saint Joseph's Phoenix, Arizona | - (ResearchInstituteInquiries@CommonSpirit.org) |
| Cancer Hematology Centers - Flint Flint, Michigan | - (wstrong@ghci.org) |
| Cancer and Hematology Centers of Western Michigan - Norton Shores Norton Shores, Michigan | |
| Carilion Roanoke Memorial Hospital Roanoke, Virginia | |
| Carle Cancer Center Urbana, Illinois | - (Research@carle.com) |
| Carle Cancer Institute Normal Normal, Illinois | - (Research@Carle.com) |
| Carle Physician Group-Effingham Effingham, Illinois | - (Research@carle.com) |
| Carle Physician Group-Mattoon/Charleston Mattoon, Illinois | - (Research@carle.com) |
| Carle at The Riverfront Danville, Illinois | - (Research@Carle.com) |
| CaroMont Health - Lincoln Cancer Center Lincolnton, North Carolina | |
| CaroMont Regional Medical Center Gastonia, North Carolina | - (tammy.cozad@caromonthealth.org) |
| Carolinas Medical Center/Levine Cancer Institute Charlotte, North Carolina | |
| Centra Alan B Pearson Regional Cancer Center Lynchburg, Virginia | - (Kevin.Patel@centrahealth.com) |
| CentraState Medical Center Freehold, New Jersey | |
| Centralia Oncology Clinic Centralia, Illinois | - (morganthaler.jodi@mhsil.com) |
| Chilton Medical Center Pompton, New Jersey | |
| Christiana Care - Union Hospital Elkton, Maryland | - (frank.crum@christianacare.org) |
| Coborn Cancer Center at Saint Cloud Hospital Saint Cloud, Minnesota | - (coborncancercenter@centracare.com) |
| Colorado Blood Cancer Institute Denver, Colorado | - (info@westernstatesncorp.org) |
| Community Hospital of Anaconda Anaconda, Montana | - (mccinfo@mtcancer.org) |
| Community Medical Center Missoula, Montana | - (mccinfo@mtcancer.org) |
| Community Medical Center Missoula, Montana | - (HemonCCTrials@geisinger.edu) |
| Condell Memorial Hospital Libertyville, Illinois | - (advocateresearch@advocatehealth.com) |
| Contra Costa Regional Medical Center Martinez, California | |
| Contra Costa Regional Medical Center Martinez, California | |
| Corewell Health Grand Rapids Hospitals - Butterworth Hospital Grand Rapids, Michigan | - (crcwm-regulatory@crcwm.org) |
| Corewell Health Reed City Hospital Reed City, Michigan | - (crcwm-regulatory@crcwm.org) |
| Cotton O'Neil Cancer Center / Stormont Vail Health Topeka, Kansas | |
| Cox Health South Hospital Springfield, Missouri | |
| CoxHealth South Hospital Springfield, Missouri | |
| Crossroads Cancer Center Effingham, Illinois | - (morganthaler.jodi@mhsil.com) |
| Dayton Physician LLC - Englewood Dayton, Ohio | - (clinical.trials@daytonncorp.org) |
| Dayton Physicians LLC-Atrium Franklin, Ohio | - (clinical.trials@daytonncorp.org) |
| Decatur Memorial Hospital Decatur, Illinois | - (morganthaler.jodi@mhsil.com) |
| Duluth Clinic Ashland Ashland, Wisconsin | - (CancerTrials@EssentiaHealth.org) |
| Edwards Comprehensive Cancer Center Huntington, West Virginia | - (Christina.Cole@chhi.org) |
| Englewood Hospital and Medical Center Englewood, New Jersey | |
| Ephrata Cancer Center Ephrata, Pennsylvania | |
| Essentia Health - Deer River Clinic Deer River, Minnesota | - (CancerTrials@EssentiaHealth.org) |
| Essentia Health - Fosston Fosston, Minnesota | - (CancerTrials@EssentiaHealth.org) |
| Essentia Health - Park Rapids Park Rapids, Minnesota | - (CancerTrials@EssentiaHealth.org) |
| Essentia Health Cancer Center Duluth, Minnesota | - (CancerTrials@EssentiaHealth.org) |
| Essentia Health Cancer Center-South University Clinic Fargo, North Dakota | - (CancerTrials@EssentiaHealth.org) |
| Essentia Health Hibbing Clinic Hibbing, Minnesota | |
| Essentia Health Saint Joseph's Medical Center Brainerd, Minnesota | - (CancerTrials@EssentiaHealth.org) |
| Essentia Health Saint Mary's - Detroit Lakes Clinic Detroit Lakes, Minnesota | - (CancerTrials@EssentiaHealth.org) |
| Essentia Health Sandstone Sandstone, Minnesota | - (CancerTrials@EssentiaHealth.org) |
| Essentia Health Virginia Clinic Virginia, Minnesota | - (CancerTrials@EssentiaHealth.org) |
| Fairbanks Memorial Hospital Fairbanks, Alaska | - (Veronica.Stevenson@foundationhealth.org) |
| Fairview Northland Medical Center Princeton, Minnesota | - (mmcorc@healthpartners.com) |
| Fairview Southdale Hospital Edina, Minnesota | - (mmcorc@healthpartners.com) |
| Flaget Memorial Hospital Bardstown, Kentucky | - (ResearchInstituteInquiries@CommonSpirit.org) |
| Geisinger Cancer Center Dickson City Dickson City, Pennsylvania | - (hemoncctrials@geisinger.edu) |
| Geisinger Cancer Services-Pottsville Pottsville, Pennsylvania | - (HemonCCTrials@geisinger.edu) |
| Geisinger Medical Center Danville, Pennsylvania | - (HemonCCTrials@geisinger.edu) |
| Geisinger Medical Center-Cancer Center Hazleton Hazleton, Pennsylvania | - (HemonCCTrials@geisinger.edu) |
| Geisinger Medical Oncology-Lewisburg Lewisburg, Pennsylvania | - (HemonCCTrials@geisinger.edu) |
| Geisinger Wyoming Valley/Henry Cancer Center Wilkes-Barre, Pennsylvania | - (HemonCCTrials@geisinger.edu) |
| Genesee Hematology Oncology PC Flint, Michigan | - (wstrong@ghci.org) |
| Gibbs Cancer Center-Gaffney Gaffney, South Carolina | - (kmertz-rivera@gibbscc.org) |
| Gibbs Cancer Center-Pelham Greer, South Carolina | - (kmertz-rivera@gibbscc.org) |
| Glens Falls Hospital Glens Falls, New York | Misty J DeCaro - (lacrosmj@glensfallshosp.org) |
| Greater Dayton Cancer Center Kettering, Ohio | - (clinical.trials@daytonncorp.org) |
| Gundersen Lutheran Medical Center La Crosse, Wisconsin | - (cancerctr@gundersenhealth.org) |
| HSHS Saint Elizabeth's Hospital O'Fallon, Illinois | - (morganthaler.jodi@mhsil.com) |
| Hackettstown Medical Center Hackettstown, New Jersey | |
| Harold Alfond Center for Cancer Care Augusta, Maine | |
| Hawaii Cancer Care - Westridge ‘Aiea, Hawaii | - (info@hawaiicancercare.com) |
| Hawaii Cancer Care Inc - Waterfront Plaza Honolulu, Hawaii | - (i.webster@hawaiicancercare.com) |
| HaysMed Hays, Kansas | |
| Hayworth Cancer Center High Point, North Carolina | |
| Heartland Regional Medical Center Saint Joseph, Missouri | - (Trisha.England2@mymlc.com) |
| Helen F Graham Cancer Center Newark, Delaware | - (lbarone@christianacare.org) |
| Hematology Oncology Associates of Fredericksburg Inc Fredericksburg, Virginia | - (cvaughn@hoafredericksburg.com) |
| Hennepin County Medical Center Minneapolis, Minnesota | - (mmcorc@healthpartners.com) |
| Hi-Line Sletten Cancer Center Havre, Montana | - (mccinfo@mtcancer.org) |
| Holy Name Hospital Teaneck, New Jersey | |
| Illinois CancerCare - Washington Washington, Illinois | - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Bloomington Bloomington, Illinois | - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Canton Canton, Illinois | - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Carthage Carthage, Illinois | - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Dixon Dixon, Illinois | |
| Illinois CancerCare-Eureka Eureka, Illinois | - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Galesburg Galesburg, Illinois | - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Kewanee Clinic Kewanee, Illinois | - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Macomb Macomb, Illinois | - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Ottawa Clinic Ottawa, Illinois | - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Pekin Pekin, Illinois | - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Peoria Peoria, Illinois | - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Peru Peru, Illinois | - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Princeton Princeton, Illinois | - (andersonj@illinoiscancercare.com) |
| Indu and Raj Soin Medical Center Beavercreek, Ohio | - (clinical.trials@daytonncorp.org) |
| Iowa Methodist Medical Center Des Moines, Iowa | |
| Jefferson Healthcare Port Townsend, Washington | |
| Kadlec Clinic Hematology and Oncology Kennewick, Washington | - (research@kadlecmed.org) |
| Kaiser Permanente Bellevue Medical Center Bellevue, Washington | - (KPWAoncologytrials@kp.org) |
| Kaiser Permanente Downtown Commons Sacramento, California | - (kpoct@kp.org) |
| Kaiser Permanente Dublin Dublin, California | |
| Kaiser Permanente Fresno Orchard Plaza Fresno, California | |
| Kaiser Permanente Medical Center - Santa Clara Santa Clara, California | - (Kpoct@kp.org) |
| Kaiser Permanente Medical Center-Vacaville Vacaville, California | - (Kpoct@kp.org) |
| Kaiser Permanente Moanalua Medical Center Honolulu, Hawaii | - (shelley.a.clark@kp.org) |
| Kaiser Permanente Northwest Portland, Oregon | - (information@kpchr.org) |
| Kaiser Permanente San Leandro San Leandro, California | - (Kpoct@kp.org) |
| Kaiser Permanente Washington Seattle, Washington | - (KPWAoncologytrials@kp.org) |
| Kaiser Permanente- Marshall Medical Offices Redwood City, California | |
| Kaiser Permanente-Deer Valley Medical Center Antioch, California | - (Kpoct@kp.org) |
| Kaiser Permanente-Franklin Denver, Colorado | - (kristi.m.bronkan@kp.org) |
| Kaiser Permanente-Fremont Fremont, California | - (Kpoct@kp.org) |
| Kaiser Permanente-Fresno Fresno, California | - (Kpoct@kp.org) |
| Kaiser Permanente-Lone Tree Lone Tree, Colorado | - (kristi.m.bronkan@kp.org) |
| Kaiser Permanente-Modesto Modesto, California | - (Kpoct@kp.org) |
| Kaiser Permanente-Oakland Oakland, California | - (Kpoct@kp.org) |
| Kaiser Permanente-Richmond Richmond, California | - (Kpoct@kp.org) |
| Kaiser Permanente-Rock Creek Lafayette, Colorado | - (kristi.m.bronkan@kp.org) |
| Kaiser Permanente-Roseville Roseville, California | - (Kpoct@kp.org) |
| Kaiser Permanente-San Francisco San Francisco, California | - (Kpoct@kp.org) |
| Kaiser Permanente-Santa Rosa Santa Rosa, California | - (Kpoct@kp.org) |
| Kaiser Permanente-Santa Teresa-San Jose San Jose, California | - (Kpoct@kp.org) |
| Kaiser Permanente-South Sacramento Sacramento, California | - (Kpoct@kp.org) |
| Kaiser Permanente-South San Francisco South San Francisco, California | - (Kpoct@kp.org) |
| Kaiser Permanente-Stockton Stockton, California | - (Kpoct@kp.org) |
| Kaiser Permanente-Vallejo Vallejo, California | - (Kpoct@kp.org) |
| Kaiser Permanente-Walnut Creek Walnut Creek, California | - (Kpoct@kp.org) |
| Kaiser San Rafael-Gallinas San Rafael, California | - (Kpoct@kp.org) |
| Kapiolani Medical Center for Women and Children Honolulu, Hawaii | |
| Kettering Medical Center Kettering, Ohio | - (clinical.trials@daytonncorp.org) |
| Kettering Medical Center Kettering, Ohio | - (clinical.trials@daytonncorp.org) |
| Kingman Regional Medical Center Kingman, Arizona | - (research@sncrf.org) |
| Kootenai Clinic Cancer Services - Post Falls Post Falls, Idaho | - (mccinfo@mtcancer.org) |
| Kootenai Clinic Cancer Services - Sandpoint Sandpoint, Idaho | - (mccinfo@mtcancer.org) |
| Kootenai Health - Coeur d'Alene Coeur d'Alene, Idaho | - (mccinfo@mtcancer.org) |
| Lake Regional Hospital Osage Beach, Missouri | - (clinicaltrials@lakeregional.com) |
| Lakeview Hospital Stillwater, Minnesota | - (mmcorc@healthpartners.com) |
| Lawrence Memorial Hospital Lawrence, Kansas | - (Stephanie.Norris@LMH.ORG) |
| Lehigh Valley Hospital - Muhlenberg Bethlehem, Pennsylvania | - (Morgan_M.Horton@lvhn.org) |
| Lehigh Valley Hospital-Cedar Crest Allentown, Pennsylvania | - (Morgan_M.Horton@lvhn.org) |
| Lehigh Valley Hospital-Hazleton Hazleton, Pennsylvania | - (Morgan_M.Horton@lvhn.org) |
| Levine Cancer Institute - Huntersville Huntersville, North Carolina | |
| Levine Cancer Institute - Rutherford Forest City, North Carolina | |
| Levine Cancer Institute - Union West Matthews, North Carolina | |
| Levine Cancer Institute-Ballantyne Charlotte, North Carolina | |
| Levine Cancer Institute-Gaston Gastonia, North Carolina | |
| Levine Cancer Institute-Rock Hill Rock Hill, South Carolina | |
| Levine Cancer Institute-SouthPark Charlotte, North Carolina | |
| Lewis Cancer and Research Pavilion at Saint Joseph's/Candler Savannah, Georgia | - (underberga@sjchs.org) |
| Liberty County Cancer Care Hinesville, Georgia | - (Oncologyresearch@sjchs.org) |
| Licking Memorial Hospital Newark, Ohio | - (Jeffh@columbusccop.org) |
| Logan Health Medical Center Kalispell, Montana | - (mccinfo@mtcancer.org) |
| Lovelace Medical Center-Saint Joseph Square Albuquerque, New Mexico | - (ZPollock@salud.unm.edu) |
| Lovelace Women's Hospital Albuquerque, New Mexico | - (AYost@nmcca.org) |
| MaineHealth Cancer Care Center of York County Sanford, Maine | |
| MaineHealth Cancer Care and IV Therapy - Brunswick Brunswick, Maine | - (clinicalresearch@mainehealth.org) |
| MaineHealth Cancer Care and IV Therapy - Sanford Sanford, Maine | - (clinicalresearch@mainehealth.org) |
| MaineHealth Cancer Care and IV Therapy - South Portland South Portland, Maine | - (clinicalresearch@mainehealth.org) |
| MaineHealth Maine Medical Center - Biddeford Biddeford, Maine | - (clinicalresearch@mainehealth.org) |
| MaineHealth Maine Medical Center- Scarborough Scarborough, Maine | - (clinicalresearch@mainehealth.org) |
| MaineHealth Penobscot Bay Hospital Rockport, Maine | - (clinicalresearch@mainehealth.org) |
| MaineHealth Waldo Hospital Belfast, Maine | - (clinicalresearch@mainehealth.org) |
| Marshfield Clinic - Wisconsin Rapids Center Wisconsin Rapids, Wisconsin | - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Clinic-Chippewa Center Chippewa Falls, Wisconsin | - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Clinic-Wausau Center Wausau, Wisconsin | - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center - Ladysmith Ladysmith, Wisconsin | - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center - Minocqua Minocqua, Wisconsin | - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center - Neillsville Neillsville, Wisconsin | - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center - Weston Weston, Wisconsin | - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center Dickinson Iron Mountain, Michigan | - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center-EC Cancer Center Eau Claire, Wisconsin | - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center-Marshfield Marshfield, Wisconsin | - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center-Rice Lake Rice Lake, Wisconsin | - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center-River Region at Stevens Point Stevens Point, Wisconsin | - (oncology.clinical.trials@marshfieldresearch.org) |
| Mayo Clinic Rochester, Minnesota | |
| Mayo Clinic Health System in Albert Lea Albert Lea, Minnesota | |
| Mayo Clinic Health System-Eau Claire Clinic Eau Claire, Wisconsin | |
| Mayo Clinic Health System-Franciscan Healthcare La Crosse, Wisconsin | |
| Mayo Clinic Health Systems-Mankato Mankato, Minnesota | |
| Medical Oncology Hematology Consultants PA Newark, Delaware | - (lbarone@christianacare.org) |
| Medical University of South Carolina Charleston, South Carolina | - (hcc-clinical-trials@musc.edu) |
| Memorial Hospital Chattanooga, Tennessee | - (Jeffh@columbusccop.org) |
| Memorial Medical Center-Las Cruces Las Cruces, New Mexico | - (Deborah.Brown@LPNT.net) |
| Mercy Cancer Center - Carmichael Carmichael, California | - (ResearchInstituteInquiries@CommonSpirit.org) |
| Mercy Cancer Center - Elk Grove Elk Grove, California | - (ResearchInstituteInquiries@CommonSpirit.org) |
| Mercy Cancer Center - Rocklin Rocklin, California | - (ResearchInstituteInquiries@CommonSpirit.org) |
| Mercy Cancer Center - Sacramento Sacramento, California | - (ResearchInstituteInquiries@CommonSpirit.org) |
| Mercy Cancer Center-West Lakes Clive, Iowa | - (cancerresearch@mercydesmoines.org) |
| Mercy Health - Paducah Cancer Center Paducah, Kentucky | - (BJWarner@mercy.com) |
| Mercy Hospital Coon Rapids, Minnesota | - (mmcorc@healthpartners.com) |
| Mercy Hospital Fort Smith Fort Smith, Arkansas | |
| Mercy Hospital Joplin Joplin, Missouri | - (esmeralda.carrillo@mercy.net) |
| Mercy Hospital Oklahoma City Oklahoma City, Oklahoma | |
| Mercy Hospital Saint Louis St Louis, Missouri | |
| Mercy Hospital South St Louis, Missouri | - (Danielle.Werle@mercy.net) |
| Mercy Hospital Springfield Springfield, Missouri | |
| Mercy Medical Center - Des Moines Des Moines, Iowa | - (cancerresearch@mercydesmoines.org) |
| Mercy Oncology and Hematology - Clayton-Clarkson Ballwin, Missouri | |
| Mercy San Juan Medical Center Carmichael, California | - (OncologyResearch@DignityHealth.org) |
| Mid Coast Hospital Brunswick, Maine | - (elizabeth.mutina@mainehealth.org) |
| Minnesota Oncology - Burnsville Burnsville, Minnesota | - (mmcorc@healthpartners.com) |
| Minnesota Oncology Hematology PA-Maplewood Maplewood, Minnesota | - (mmcorc@healthpartners.com) |
| Minnesota Oncology Hematology PA-Woodbury Woodbury, Minnesota | - (mmcorc@healthpartners.com) |
| Mission Hope Medical Oncology - Arroyo Grande Arroyo Grande, California | - (ResearchInstituteInquiries@CommonSpirit.org) |
| Mission Hope Medical Oncology - Santa Maria Santa Maria, California | - (ResearchInstituteInquiries@CommonSpirit.org) |
| Missouri Baptist Medical Center St Louis, Missouri | |
| Missouri Baptist Sullivan Hospital Sullivan, Missouri | |
| Missouri Baptist Sullivan Hospital Sullivan, Missouri | |
| Montana Cancer Consortium NCORP Billings, Montana | - (mccinfo@mtcancer.org) |
| Montefiore Medical Center - Moses Campus The Bronx, New York | - (eskwak@montefiore.org) |
| Montefiore Medical Center-Einstein Campus The Bronx, New York | - (eskwak@montefiore.org) |
| Monticello Cancer Center Monticello, Minnesota | - (mmcorc@healthpartners.com) |
| Monument Health Rapid City Hospital Rapid City, South Dakota | - (research@monument.health) |
| Morristown Medical Center Morristown, New Jersey | |
| Morton Plant Hospital Clearwater, Florida | |
| Munson Medical Center Traverse City, Michigan | - (crcwm-regulatory@crcwm.org) |
| MyMichigan Medical Center Alpena Alpena, Michigan | - (CVResearch@mymichigan.org) |
| MyMichigan Medical Center Gladwin Gladwin, Michigan | - (CVResearch@mymichigan.org) |
| MyMichigan Medical Center Gratiot Alma, Michigan | - (CVResearch@mymichigan.org) |
| MyMichigan Medical Center Midland Midland, Michigan | - (CVResearch@mymichigan.org) |
| MyMichigan Medical Center Mount Pleasant Mount Pleasant, Michigan | - (CVResearch@mymichigan.org) |
| MyMichigan Medical Center Saginaw Saginaw, Michigan | - (MCRCwebsitecontactform@stjoeshealth.org) |
| MyMichigan Medical Center Tawas Tawas City, Michigan | - (MCRCwebsitecontactform@stjoeshealth.org) |
| NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro Jonesboro, Arkansas | |
| New Ulm Medical Center New Ulm, Minnesota | - (mmcorc@healthpartners.com) |
| Newton Medical Center Newton, New Jersey | |
| North Memorial Medical Health Center Robbinsdale, Minnesota | - (mmcorc@healthpartners.com) |
| Northside Hospital Atlanta, Georgia | - (ClinicalTrials@northside.com) |
| Northside Hospital - Duluth Duluth, Georgia | - (Clinical.trials@northside.com) |
| Northside Hospital - Gwinnett Lawrenceville, Georgia | - (Clinical.trials@northside.com) |
| OSF Saint Anthony Medical Center Rockford, Illinois | |
| OSF Saint Anthony's Health Center Alton, Illinois | |
| OSF Saint Francis Hospital and Medical Group Escanaba, Michigan | - (ewd_research_admin@hshs.org) |
| Oncology Associates at Mercy Medical Center Cedar Rapids, Iowa | |
| OptumCare Cancer Care at Charleston Las Vegas, Nevada | - (research@sncrf.org) |
| OptumCare Cancer Care at Seven Hills Henderson, Nevada | - (research@sncrf.org) |
| Overlook Medical Center Summit, New Jersey | |
| PCR Oncology Arroyo Grande, California | - (research@sncrf.org) |
| Pacific Central Coast Health Center-San Luis Obispo San Luis Obispo, California | - (ResearchInstituteInquiries@CommonSpirit.org) |
| Pali Momi Medical Center ‘Aiea, Hawaii | |
| Park Nicollet Clinic - Saint Louis Park Saint Louis Park, Minnesota | - (mmcorc@healthpartners.com) |
| Parkland Health Center - Farmington Farmington, Missouri | |
| Penrose-Saint Francis Healthcare Colorado Springs, Colorado | - (ResearchInstituteInquiries@CommonSpirit.org) |
| Physicians' Clinic of Iowa PC Cedar Rapids, Iowa | |
| Pocono Medical Center East Stroudsburg, Pennsylvania | - (Morgan_M.Horton@lvhn.org) |
| Presbyterian Kaseman Hospital Albuquerque, New Mexico | - (WBurman@phs.org) |
| Presbyterian Rust Medical Center/Jorgensen Cancer Center Rio Rancho, New Mexico | |
| Prisma Health Cancer Institute - Butternut Greenville, South Carolina | |
| Prisma Health Cancer Institute - Easley Easley, South Carolina | - (Kim.Williams3@prismahealth.org) |
| Prisma Health Cancer Institute - Eastside Greenville, South Carolina | |
| Prisma Health Cancer Institute - Faris Greenville, South Carolina | |
| Prisma Health Cancer Institute - Greer Greer, South Carolina | |
| Prisma Health Cancer Institute - Seneca Seneca, South Carolina | |
| Prisma Health Cancer Institute - Spartanburg Boiling Springs, South Carolina | |
| Providence Medical Foundation - Santa Rosa Santa Rosa, California | |
| Providence Saint Mary Regional Cancer Center Walla Walla, Washington | - (Cheryl.Dodd@providence.org) |
| Queen's Cancer Center - Kuakini Honolulu, Hawaii | |
| Queen's Cancer Center - POB I Honolulu, Hawaii | |
| Queen's Medical Center Honolulu, Hawaii | |
| Queens Hospital Center Jamaica, New York | Linda Bulone - (buloneL@nychhc.org) |
| Regional Cancer Care - Jesup Jesup, Georgia | - (Oncologyresearch@sjchs.org) |
| Regions Hospital Saint Paul, Minnesota | - (mmcorc@healthpartners.com) |
| Reid Health Richmond, Indiana | - (clinical.trials@daytonncorp.org) |
| Rice Memorial Hospital Willmar, Minnesota | - (mmcorc@healthpartners.com) |
| Ridgeview Medical Center Waconia, Minnesota | - (mmcorc@healthpartners.com) |
| Rocky Mountain Cancer Centers - Centennial Centennial, Colorado | - (info@westernstatesncorp.org) |
| Rocky Mountain Cancer Centers-Aurora Aurora, Colorado | - (info@westernstatesncorp.org) |
| Rocky Mountain Cancer Centers-Boulder Boulder, Colorado | - (info@westernstatesncorp.org) |
| Rocky Mountain Cancer Centers-Littleton Littleton, Colorado | - (info@westernstatesncorp.org) |
| Rocky Mountain Cancer Centers-Midtown Denver, Colorado | - (info@westernstatesncorp.org) |
| Rocky Mountain Cancer Centers-Rose Denver, Colorado | - (info@westernstatesncorp.org) |
| Rocky Mountain Cancer Centers-Sky Ridge Lone Tree, Colorado | - (info@westernstatesncorp.org) |
| Rocky Mountain Cancer Centers-Thornton Thornton, Colorado | - (info@westernstatesncorp.org) |
| Rush-Copley Healthcare Center Yorkville, Illinois | - (Cancer.Research@rushcopley.com) |
| Rush-Copley Medical Center Aurora, Illinois | - (Cancer.Research@rushcopley.com) |
| SMC Center for Hematology Oncology Union Union, South Carolina | - (kmertz-rivera@gibbscc.org) |
| SSM Health Good Samaritan Mount Vernon, Illinois | - (gayla.hall@ssmhealth.com) |
| Saint Agnes Medical Center Fresno, California | - (medresearch@samc.com) |
| Saint Alphonsus Cancer Care Center-Baker City Baker City, Oregon | - (mccinfo@mtcancer.org) |
| Saint Alphonsus Cancer Care Center-Boise Boise, Idaho | - (stephanie.couch@stjoeshealth.org) |
| Saint Alphonsus Cancer Care Center-Caldwell Caldwell, Idaho | - (stephanie.couch@stjoeshealth.org) |
| Saint Alphonsus Cancer Care Center-Nampa Nampa, Idaho | - (mccinfo@mtcancer.org) |
| Saint Alphonsus Cancer Care Center-Ontario Ontario, Oregon | - (mccinfo@mtcancer.org) |
| Saint Anthony North Hospital Westminster, Colorado | - (ResearchInstituteInquiries@CommonSpirit.org) |
| Saint Anthony's Hospital Cancer Care Center St. Petersburg, Florida | - (Research.CTO@baycare.org) |
| Saint Elizabeth Youngstown Hospital Youngstown, Ohio | - (clinical.trials@daytonncorp.org) |
| Saint Francis Cancer Center Greenville, South Carolina | - (ResearchInstituteInquiries@CommonSpirit.org) |
| Saint Francis Cancer Center Greenville, South Carolina | - (melissa_beckman@bshsi.org) |
| Saint Francis Hospital Greenville, South Carolina | - (melissa_beckman@bshsi.org) |
| Saint Francis Regional Medical Center Shakopee, Minnesota | - (mmcorc@healthpartners.com) |
| Saint John's Hospital - Healtheast Maplewood, Minnesota | - (mmcorc@healthpartners.com) |
| Saint Joseph Hospital East Lexington, Kentucky | - (ResearchInstituteInquiries@CommonSpirit.org) |
| Saint Joseph London London, Kentucky | - (ResearchInstituteInquiries@CommonSpirit.org) |
| Saint Joseph Mount Sterling Mount Sterling, Kentucky | - (ResearchInstituteInquiries@CommonSpirit.org) |
| Saint Joseph's Hospital/Children's Hospital-Tampa Tampa, Florida | - (jennifer.manns@baycare.org) |
| Saint Joseph's Medical Center Stockton, California | |
| Saint Joseph's/Candler - Bluffton Campus Bluffton, South Carolina | - (underberga@sjchs.org) |
| Saint Louis Cancer and Breast Institute-Ballwin Ballwin, Missouri | |
| Saint Luke's Hospital of Duluth Duluth, Minnesota | - (kdean@slhduluth.com) |
| Saint Vincent Hospital Cancer Center Green Bay Green Bay, Wisconsin | - (ewd_research_admin@hshs.org) |
| Saint Vincent Hospital Cancer Center at Oconto Falls Oconto Falls, Wisconsin | - (ewd_research_admin@hshs.org) |
| Saint Vincent Hospital Cancer Center at Saint Mary's Green Bay, Wisconsin | - (ewd_research_admin@hshs.org) |
| Saint Vincent Hospital Cancer Center at Sheboygan Sheboygan, Wisconsin | - (ewd_research_admin@hshs.org) |
| Saint Vincent Hospital Cancer Center at Sturgeon Bay Sturgeon Bay, Wisconsin | - (ewd_research_admin@hshs.org) |
| Sainte Genevieve County Memorial Hospital Sainte Genevieve, Missouri | |
| Salina Regional Health Center Salina, Kansas | - (mleepers@srhc.com) |
| Sechler Family Cancer Center Lebanon, Pennsylvania | - (doxenberg@wellspan.org) |
| Sheboygan Physicians Group Sheboygan, Wisconsin | - (ewd_research_admin@hshs.org) |
| Shenandoah Oncology PC Winchester, Virginia | - (William.Houck@usoncology.com) |
| Sinai Hospital of Baltimore Baltimore, Maryland | - (pridgely@lifebridgehealth.org) |
| South Carolina Cancer Specialists PC Hilton Head Island, South Carolina | - (underberga@sjchs.org) |
| South Florida Baptist Hospital Plant City, Florida | - (Claudia.Quinones@baycare.org) |
| Southern Illinois University School of Medicine Springfield, Illinois | |
| Spartanburg Medical Center Spartanburg, South Carolina | - (kmertz-rivera@gibbscc.org) |
| Springfield Clinic Springfield, Illinois | |
| Springfield Memorial Hospital Springfield, Illinois | - (pallante.beth@mhsil.com) |
| Straub Benioff Medical Center Honolulu, Hawaii | |
| Straub Pearlridge Clinic ‘Aiea, Hawaii | |
| Strecker Cancer Center-Belpre Belpre, Ohio | - (Jeffh@columbusccop.org) |
| Swedish Cancer Institute-Edmonds Edmonds, Washington | - (PCRC-NCORP@Swedish.org) |
| Swedish Cancer Institute-Issaquah Issaquah, Washington | - (PCRC-NCORP@Swedish.org) |
| Swedish Medical Center-First Hill Seattle, Washington | - (PCRC-NCORP@Swedish.org) |
| The Queen's Medical Center - West Oahu ‘Ewa Beach, Hawaii | - (rohta@queens.org) |
| The Radiation Oncology Center-Hilton Head/Bluffton Hilton Head Island, South Carolina | - (underberga@sjchs.org) |
| The University of Kansas Cancer Center - Olathe Olathe, Kansas | - (OlatheCCResearch@kumc.edu) |
| ThedaCare Cancer Care - Berlin Berlin, Wisconsin | - (ResearchDept@thedacare.org) |
| ThedaCare Cancer Care - New London New London, Wisconsin | - (ResearchDept@thedacare.org) |
| ThedaCare Cancer Care - Oshkosh Oshkosh, Wisconsin | - (ResearchDept@thedacare.org) |
| ThedaCare Cancer Care - Shawano Shawano, Wisconsin | - (ResearchDept@thedacare.org) |
| ThedaCare Cancer Care - Waupaca Waupaca, Wisconsin | - (ResearchDept@thedacare.org) |
| ThedaCare Regional Cancer Center Appleton, Wisconsin | - (ResearchDept@thedacare.org) |
| ThedaCare Regional Medical Center - Neenah Neenah, Wisconsin | - (ResearchDept@thedacare.org) |
| Tidelands Georgetown Memorial Hospital Georgetown, South Carolina | - (broe@tidelandshealth.org) |
| Trinity Health Grand Rapids Hospital Grand Rapids, Michigan | - (crcwm-regulatory@crcwm.org) |
| Trinity Health Muskegon Hospital Muskegon, Michigan | - (crcwm-regulatory@crcwm.org) |
| Trinity Health Saint Joseph Mercy Hospital Ann Arbor Ann Arbor, Michigan | - (MCRCwebsitecontactform@stjoeshealth.org) |
| Trinity Health Saint Joseph Mercy Oakland Hospital Pontiac, Michigan | - (MCRCwebsitecontactform@stjoeshealth.org) |
| UI Health Care Mission Cancer and Blood - Ankeny Clinic Ankeny, Iowa | |
| UI Health Care Mission Cancer and Blood - Des Moines Clinic Des Moines, Iowa | |
| UI Health Care Mission Cancer and Blood - Laurel Clinic Des Moines, Iowa | |
| UI Health Care Mission Cancer and Blood - Waukee Clinic Waukee, Iowa | |
| UI Health Care Mission Cancer and Blood - West Des Moines Clinic Clive, Iowa | |
| UM Baltimore Washington Medical Center/Tate Cancer Center Glen Burnie, Maryland | |
| UM Saint Joseph Medical Center Towson, Maryland | - (Jeanmarie.downing@umm.edu) |
| United Hospital Saint Paul, Minnesota | - (mmcorc@healthpartners.com) |
| University Health Truman Medical Center Kansas City, Missouri | |
| University of Iowa Healthcare Cancer Services Quad Cities Bettendorf, Iowa | - (katherine-daprile@uiowa.edu) |
| University of Iowa/Holden Comprehensive Cancer Center Iowa City, Iowa | |
| University of Kansas Cancer Center - Lee's Summit Lee's Summit, Missouri | - (KUCC_Navigation@kumc.edu) |
| University of Kansas Cancer Center - North Kansas City, Missouri | - (KUCC_Navigation@kumc.edu) |
| University of Kansas Cancer Center-Overland Park Overland Park, Kansas | - (KUCC_Navigation@kumc.edu) |
| University of Kansas Health System Saint Francis Campus Topeka, Kansas | |
| University of Kansas Hospital-Indian Creek Campus Overland Park, Kansas | - (KUCC_Navigation@kumc.edu) |
| University of Kansas Hospital-Westwood Cancer Center Westwood, Kansas | - (KUCC_Navigation@kumc.edu) |
| University of Maryland/Greenebaum Cancer Center Baltimore, Maryland | |
| University of Michigan Health - West Wyoming, Michigan | - (crcwm-regulatory@crcwm.org) |
| University of New Mexico Cancer Center Albuquerque, New Mexico | - (HSC-ClinicalTrialInfo@salud.unm.edu) |
| University of Wisconsin Carbone Cancer Center - University Hospital Madison, Wisconsin | - (clinicaltrials@cancer.wisc.edu) |
| VCU Community Memorial Health Center South Hill, Virginia | - (nemer.elmouallem@vcuhealth.org) |
| VCU Massey Cancer Center at Stony Point Richmond, Virginia | - (ctoclinops@vcu.edu) |
| Vince Lombardi Cancer Clinic - Oshkosh Oshkosh, Wisconsin | - (ncorp@aurora.org) |
| Vince Lombardi Cancer Clinic-Sheboygan Sheboygan, Wisconsin | - (ncorp@aurora.org) |
| Vince Lombardi Cancer Clinic-Two Rivers Two Rivers, Wisconsin | - (ncorp@aurora.org) |
| Virginia Commonwealth University/Massey Cancer Center Richmond, Virginia | - (CTOclinops@vcu.edu) |
| Wake Forest NCORP Research Base Winston-Salem, North Carolina | Glenn Lesser, MD - (ncorp@wakehealth.edu) Beth Reboussin, PhD - (ncorp@wakehealth.edu) |
| Wake Forest University Health Sciences Winston-Salem, North Carolina | |
| Wake Forest University at Clemmons Clemmons, North Carolina | |
| WellSpan Medical Oncology and Hematology Hanover, Pennsylvania | |
| Wellspan Health - York Cancer Center York, Pennsylvania | |
| West Michigan Cancer Center Kalamazoo, Michigan | - (crcwm-regulatory@crcwm.org) |
| Westfields Hospital/Cancer Center of Western Wisconsin New Richmond, Wisconsin | - (mmcorc@healthpartners.com) |
| Wilcox Memorial Hospital and Kauai Medical Clinic Lihue, Hawaii | |
| William E Kahlert Regional Cancer Center/Sinai Hospital Westminster, Maryland | |
| Winter Haven Hospital Winter Haven, Florida | - (Research.CTO@baycare.org) |
| Woodland Cancer Care Center Michigan City, Indiana | - (sally.arnett@franciscanalliance.org) |
| Woodland Memorial Hospital Woodland, California | - (ResearchInstituteInquiries@CommonSpirit.org) |
The Vanguard Study: Testing a New Way to Screen for Cancer
ctrrecruit@vcu.edu
NCT06995898
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:
* Ages 45-75 years old
* Agree to provide blood samples for possible MCD testing at enrollment and at 1 year following enrollment
* Agree to allow collection of information from their medical records for study-related purposes
* Understand and be able to complete informed consent and participant questionnaires in English, Spanish, or Arabic
* Note: Eligibility for Spanish and Arabic languages are at the Hub's discretion
Exclusion Criteria:
* Solid malignant tumor or blood cancer diagnosis, with or without treatment, within the last 5 years
* Note: Persons with a history of in situ cancers (e.g., ductal carcinoma in situ of the breast, cervical cancer in situ, atypical melanocytic hyperplasia or melanoma in situ) or nonmelanoma skin cancer are eligible
* Ongoing cancer diagnostic work-up
* Ongoing participation in another study of an investigational cancer screening test or technology
* Currently breastfeeding or pregnant, or planning to become pregnant in the next year PROCEDURE: Biospecimen Collection, DEVICE: Device Usage, OTHER: Electronic Health Record Review, PROCEDURE: Multi-Cancer Detection Test, PROCEDURE: Multi-Cancer Detection Test, OTHER: Questionnaire Administration
Bladder Carcinoma, Breast Carcinoma, Colorectal Carcinoma, Esophageal Carcinoma, Gastric Carcinoma, Liver Carcinoma, Lung Carcinoma, Malignant Solid Neoplasm, Ovarian Carcinoma, Pancreatic Carcinoma, Prostate Carcinoma
I'm interested
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Show 34 locations
Study Locations
Hide all locations
| Location | Contacts |
|---|---|
| Cancer Care and Hematology-Fort Collins Fort Collins, Colorado | Site Public Contact - (ctsucontact@westat.com) |
| Henry Ford Cancer Institute-Downriver Brownstown, Michigan | Site Public Contact - (CTOResearch@hfhs.org) |
| Henry Ford Hospital Detroit, Michigan | Site Public Contact - (CTOResearch@hfhs.org) |
| Henry Ford Macomb Hospital-Clinton Township Clinton Township, Michigan | Site Public Contact - (CTOResearch@hfhs.org) |
| Henry Ford Medical Center Sterling Heights, Michigan | Site Public Contact - (ctsucontact@westat.com) |
| Henry Ford Medical Center - Detroit Northwest Detroit, Michigan | Site Public Contact - (kkeenan1@hfhs.org) |
| Henry Ford Medical Center - Livonia Livonia, Michigan | Site Public Contact - (kkeenan1@hfhs.org) |
| Henry Ford Medical Center - Plymouth Plymouth, Michigan | Site Public Contact - (kkeenan1@hfhs.org) |
| Henry Ford Medical Center - Royal Oak Royal Oak, Michigan | Site Public Contact - (kkeenan1@hfhs.org) |
| Henry Ford Medical Center - Troy Troy, Michigan | Site Public Contact - (kkeenan1@hfhs.org) |
| Henry Ford Medical Center-Columbus Novi, Michigan | Site Public Contact - (CTOResearch@hfhs.org) |
| Henry Ford Medical Center-Cottage Grosse Pointe Farms, Michigan | |
| Henry Ford Medical Center-Fairlane Dearborn, Michigan | Site Public Contact - (CTOResearch@hfhs.org) |
| Henry Ford West Bloomfield Hospital West Bloomfield, Michigan | Site Public Contact - (CTOResearch@hfhs.org) |
| Henry Ford Wyandotte Hospital Wyandotte, Michigan | Site Public Contact - (nhay@hfhs.org) |
| Inova Fair Oaks Hospital Fairfax, Virginia | Site Public Contact - (Stephanie.VanBebber@inova.org) |
| Inova Schar Cancer Institute Fairfax, Virginia | Site Public Contact - (Stephanie.VanBebber@inova.org) |
| Kaiser Permanente Moanalua Medical Center Honolulu, Hawaii | Site Public Contact - (shelley.a.clark@kp.org) |
| Kaiser Permanente-Division of Research Pleasanton, California | |
| Kaiser Permanente-Franklin Denver, Colorado | Site Public Contact - (kristi.m.bronkan@kp.org) |
| Kaiser Permanente-Lone Tree Lone Tree, Colorado | Site Public Contact - (kristi.m.bronkan@kp.org) |
| Kaiser Permanente-Rock Creek Lafayette, Colorado | Site Public Contact - (kristi.m.bronkan@kp.org) |
| Keefe Memorial Hospital Cheyenne Wells, Colorado | Site Public Contact - (cmillsap@keefemh.org) |
| Medical Center of the Rockies Loveland, Colorado | |
| Poudre Valley Hospital Fort Collins, Colorado | |
| Sentara Martha Jefferson Hospital Charlottesville, Virginia | |
| Sentara Norfolk General Hospital Norfolk, Virginia | |
| UCHealth Greeley Hospital Greeley, Colorado | Site Public Contact - (ctsucontact@westat.com) |
| UNC Lineberger Comprehensive Cancer Center Chapel Hill, North Carolina | Site Public Contact - (cancerclinicaltrials@med.unc.edu) |
| University of Oklahoma Health Sciences Center Oklahoma City, Oklahoma | Site Public Contact - (ou-clinical-trials@ouhsc.edu) |
| VCU Community Memorial Health Center South Hill, Virginia | Site Public Contact - (nemer.elmouallem@vcuhealth.org) |
| VCU Massey Cancer Center at Stony Point Richmond, Virginia | Site Public Contact - (ctoclinops@vcu.edu) |
| VCU Massey Comprehensive Cancer Center Richmond, Virginia | Site Public Contact - (CTOclinops@vcu.edu) |
| Washington University School of Medicine St Louis, Missouri | Site Public Contact - (info@siteman.wustl.edu) |
National Cancer Institute "Cancer Moonshot Biobank" (moonshot)
Castellanos, Natasha, Guzy - castellanosn@vcu.edu
Poklepovic, Andrew, S
NCT04314401
HM20020956
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:
* Is consistent with OR has been diagnosed with one of the following:
* Colorectal cancer: stage IV
* Non-small cell or small cell lung cancer: stage III/IV
* Prostate cancer: metastatic prostate cancer
* Gastric cancer, not otherwise specified (NOS): stage IV
* Esophageal cancer, NOS: stage IV
* Adenocarcinoma of gastroesophageal junction: stage IV
* High grade serous ovarian cancer: stage III/IV
* Invasive breast carcinoma: stage III/IV
* Melanoma: stage III/IV
* Acute myeloid leukemia
* Multiple myeloma
* For the purposes of this study,
* Re-staging is allowed
* Having more than one primary cancer is allowed, if the patient is being treated solely for one of the eligible cancers listed above
* Patient should fit in one of the following four clinical scenarios (a-d)
* Undergoing diagnostic workup for one of the diseases listed for which treatment will likely include a new regimen of standard of care therapy OR
* Scheduled to begin treatment with a new regimen of standard of care therapy OR
* Currently progressing on a regimen of standard of care therapy OR
* Currently being treated with a regimen standard of care therapy, without evidence of progression
* Requirements for fresh tissue biospecimen collections at enrollment:
* For clinical scenarios a, b, and c above, freshly collected tumor tissue or bone marrow (BM) aspirate must be submitted at enrollment
* For clinical scenarios a and b, the fresh tissue collection must be prior to starting therapy
* For clinical scenario a, the biospecimen collection must be part of a standard of care medical procedure
* For clinical scenarios b or c, the biospecimen collection may be part of a standard of care medical procedure OR
* The biospecimen collection may be part of a study-specific procedure ("research only biopsy"), when the patient has a tumor amenable to image guided or direct vision biopsy and is willing and able to undergo a tumor biopsy for molecular profiling
* Note: For research-only biopsies, the biopsy must not be associated with a significant risk of severe or major complications or death; the procedure cannot be a mediastinal, laparoscopic, open or endoscopic biopsy; nor can the procedure be a brain biopsy; nor can the patient be under the age of majority as determined by each U.S. state
* Requirements for archival tissue:
* For clinical scenarios a and b above, archival tissue as outlined below must be submitted IF AVAILABLE
* For clinical scenarios c and d above, archival tissue as outlined below is REQUIRED
* Pre-existing archival material (formalin-fixed, paraffin-embedded \[FFPE\] block, BM aspirate, or unstained slides) that:
* Contains the cancer type for which the participant is enrolled, and
* Was collected no more than 5 years prior to initiation of therapy, and
* Contains at least a surface area of 5 mm\^2 and optimal surface area of 25 mm\^2 or 3-5 mL cryopreserved bone marrow aspirate to yield 200 million bone marrow mononuclear cells, and
* Contains at least 10% tumor content. 70% tumor content is optimal, and
* No more than 1 line of standard of care systemic therapy was administered from the date of archival material collection to the date of initiation of therapy
* Requirements for blood collection: ALL scenarios require fresh blood collection at enrollment
* Blood collection for clinical scenarios a, b, and c must take place within 1 week of fresh tumor specimen collection
* Blood collection for clinical scenario d must take place within 4 weeks of enrollment, and while patient is on treatment
* Age 13 or older
* Any sex
* Eastern Cooperative Oncology Group (ECOG) performance status (PS) of 0, 1, or 2
* Ability to understand and willingness to sign an informed consent document. Consent may be provided by a Legally Authorized Representative (LAR) in accordance with 45 CFR 46.102(i)
* NCI PDMR INCLUSION CRITERIA: Patients with CRC with mismatch repair deficient (dMMR) or microsatellite instability-high (MSI-H) status
* NCI PDMR INCLUSION CRITERIA: Patients with CRC who are 40 years old or younger at time of collection irrespective of mismatch repair deficient (dMMR) or microsatellite instability-high (MSI-H) status
* NCI PDMR INCLUSION CRITERIA: Patients with BRCA that are either
* Any race/ethnicity with hormone receptor positive (ER+PR+, ER+PR-, or ER-PR+)
* African American with triple negative (ER-PR-HER2-)
* NCI PDMR INCLUSION CRITERIA: Patients with lung cancer (LCA), prostate cancer (PCA), gastroesophageal cancer (GEC), ovarian cancer (OV), acute myeloid leukemia (AML), multiple myeloma (MML)
Exclusion Criteria:
* Treated with or has already begun treatment with a non-standard of care therapeutic agent (investigational) in an interventional clinical trial
* For the purposes of this study, past enrollment in clinical trials whereby the patient was randomized and treated with standard-of-care anti-cancer treatment (chemotherapy regimen, surgery and radiation therapy) is allowed
* Uncontrolled intercurrent illness that in the physician's assessment would pose undue risk for biopsy
* Use of full dose coumarin-derivative anticoagulants such as warfarin are prohibited. Patients may be switched to low molecular weight (LMW) heparin at physician discretion
* Low molecular weight (LMW) heparin is permitted for prophylactic or therapeutic use
* Factor X inhibitors are permitted
* Use of anti-platelet drugs are permitted
* Stopping the anticoagulation treatment for biopsy, bone marrow aspirate, or resection should be per site standard operating procedure (SOP)
* NCI PDMR EXCLUSION CRITERIA: Patients with complete response
* NCI PDMR EXCLUSION CRITERIA: Patients with invasive fungal infections
* NCI PDMR EXCLUSION CRITERIA: Patients with active and/or uncontrolled infections or who are still recovering from an infection
* Actively febrile patients with uncertain etiology of febrile episode
* All antibiotics for non-prophylactic treatment of infection should be completed at least 1 week (7 days) prior to collection
* No recurrence of fever or other symptoms related to infection for at least 1 week (7 days) following completion of antibiotics
* NCI PDMR EXCLUSION CRITERIA: Patients with human immunodeficiency virus (HIV), active or chronic hepatitis (i.e. quantifiable hepatitis B virus \[HBV\]-deoxyribonucleic acid \[DNA\] and/or positive hepatitis B surface antigen \[HbsAg\], quantifiable hepatitis C virus \[HCV\]-ribonucleic acid \[RNA\]) or known history of HBV/HCV without documented resolution PROCEDURE: Biospecimen Collection, PROCEDURE: Computed Tomography, PROCEDURE: Magnetic Resonance Imaging, OTHER: Medical Chart Review, PROCEDURE: Paracentesis, PROCEDURE: Positron Emission Tomography
Acute Myeloid Leukemia, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8, Clinical Stage IV Esophageal Adenocarcinoma AJCC v8, Clinical Stage IV Gastric Cancer AJCC v8, Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8, Esophageal Carcinoma, Fallopian Tube Carcinoma, Gastric Carcinoma, Hormone Receptor-Positive Breast Carcinoma, Invasive Breast Carcinoma, Lung Non-Small Cell Carcinoma, Lung Small Cell Carcinoma, Malignant Solid Neoplasm, Melanoma, Metastatic Prostate Carcinoma, Multiple Myeloma, Ovarian Carcinoma, Ovarian High Grade Serous Adenocarcinoma, Primary Peritoneal Carcinoma, Stage III Fallopian Tube Cancer AJCC v8, Stage III Lung Cancer AJCC v8, Stage III Ovarian Cancer AJCC v8, Stage IV Colorectal Cancer AJCC v8, Stage IV Fallopian Tube Cancer AJCC v8, Stage IV Lung Cancer AJCC v8, Stage IV Ovarian Cancer AJCC v8, Stage IVB Prostate Cancer AJCC v8, Triple-negative Breast Carcinoma
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Study Locations
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| Location | Contacts |
|---|---|
| AIS Cancer Center at San Joaquin Community Hospital Bakersfield, California | |
| Alliance for Childhood Diseases/Cure 4 the Kids Foundation Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Audie L Murphy VA Hospital San Antonio, Texas | |
| Aurora Saint Luke's Medical Center Milwaukee, Wisconsin | Site Public Contact - (ncorp@aurora.org) |
| Bayhealth Hospital Kent Campus Dover, Delaware | Site Public Contact - (clinical_trials@bayhealth.org) |
| Bayhealth Hospital Sussex Campus Milford, Delaware | Site Public Contact - (clinical_trials@bayhealth.org) |
| Blank Children's Hospital Des Moines, Iowa | |
| Boca Raton Regional Hospital Boca Raton, Florida | |
| Broward Health Medical Center Fort Lauderdale, Florida | Site Public Contact - (Allison.bruce@nemours.org) |
| Broward Health North Deerfield Beach, Florida | |
| Cancer Care Specialists of Illinois - Decatur Decatur, Illinois | Site Public Contact - (morganthaler.jodi@mhsil.com) |
| Carle Cancer Center Urbana, Illinois | Site Public Contact - (Research@carle.com) |
| Carle Physician Group-Mattoon/Charleston Mattoon, Illinois | Site Public Contact - (Research@carle.com) |
| Carle at The Riverfront Danville, Illinois | Site Public Contact - (Research@Carle.com) |
| Carson Tahoe Regional Medical Center Carson City, Nevada | Site Public Contact - (research@sncrf.org) |
| Centra Alan B Pearson Regional Cancer Center Lynchburg, Virginia | |
| Centro Comprensivo de Cancer de UPR San Juan, | Site Public Contact - (ctsucontact@westat.com) |
| Chelsea Hospital Chelsea, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Children's Hospital New Orleans New Orleans, Louisiana | |
| Children's Hospital at Montefiore The Bronx, New York | Site Public Contact - (aaraiza@montefiore.org) |
| Chilton Medical Center Pompton, New Jersey | |
| Comprehensive Cancer Centers of Nevada Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Comprehensive Cancer Centers of Nevada - Central Valley Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Comprehensive Cancer Centers of Nevada - Town Center Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Corewell Health Grand Rapids Hospitals - Butterworth Hospital Grand Rapids, Michigan | Site Public Contact - (crcwm-regulatory@crcwm.org) |
| CoxHealth South Hospital Springfield, Missouri | |
| Decatur Memorial Hospital Decatur, Illinois | Site Public Contact - (morganthaler.jodi@mhsil.com) |
| Dickinson County Healthcare System Iron Mountain, Michigan | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| ECU Health Medical Center Greenville, North Carolina | Site Public Contact - (research@ecuhealth.org) |
| ECU Health Oncology Kinston Kinston, North Carolina | Site Public Contact - (research@ecuhealth.org) |
| East Carolina University Greenville, North Carolina | Site Public Contact - (eubankss@ecu.edu) |
| Edwards Comprehensive Cancer Center Huntington, West Virginia | Site Public Contact - (Christina.Cole@chhi.org) |
| FirstHealth of the Carolinas-Moore Regional Hospital Pinehurst, North Carolina | Site Public Contact - (jcwilliams@firsthealth.org) |
| Freeman Health System Joplin, Missouri | Site Public Contact - (LJCrockett@freemanhealth.com) |
| Gibbs Cancer Center-Gaffney Gaffney, South Carolina | Site Public Contact - (kmertz-rivera@gibbscc.org) |
| Gibbs Cancer Center-Pelham Greer, South Carolina | Site Public Contact - (kmertz-rivera@gibbscc.org) |
| Good Samaritan Hospital - Cancer Centers of Colorado Lafayette, Colorado | Site Public Contact - (peaksresearch@imail.org) |
| Gulf Health Hospitals Inc/Infirmary Cancer Care - Malbis Daphne, Alabama | Site Public Contact - (donna.goggins@infirmaryhealth.org) |
| Gulf Health Hospitals Inc/Infirmary Cancer Care - Saraland Saraland, Alabama | Site Public Contact - (donna.goggins@infirmaryhealth.org) |
| Harold Alfond Center for Cancer Care Augusta, Maine | |
| Hartford Hospital Hartford, Connecticut | |
| Heartland Regional Medical Center Saint Joseph, Missouri | Site Public Contact - (Trisha.England2@mymlc.com) |
| Hope Cancer Care of Nevada Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| Illinois CancerCare - Washington Washington, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Bloomington Bloomington, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Galesburg Galesburg, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Pekin Pekin, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Illinois CancerCare-Peoria Peoria, Illinois | Site Public Contact - (andersonj@illinoiscancercare.com) |
| Intermountain Health Platte Valley Hospital Brighton, Colorado | Site Public Contact - (peaksresearch@imail.org) |
| Iowa Methodist Medical Center Des Moines, Iowa | |
| John H Stroger Jr Hospital of Cook County Chicago, Illinois | |
| Kingman Regional Medical Center Kingman, Arizona | Site Public Contact - (research@sncrf.org) |
| LSU Health Sciences Center at Shreveport Shreveport, Louisiana | |
| Lewis Cancer and Research Pavilion at Saint Joseph's/Candler Savannah, Georgia | Site Public Contact - (underberga@sjchs.org) |
| Lutheran Hospital - Cancer Centers of Colorado Golden, Colorado | Site Public Contact - (peaksresearch@imail.org) |
| MMP Surgical Care Casco Bay Portland, Maine | Site Public Contact - (ClinicalResearch@mmc.org) |
| Maine Children's Cancer Program Scarborough, Maine | Site Public Contact - (clinicalresearch@mainehealth.org) |
| Maine Medical Partners Neurology Scarborough, Maine | Site Public Contact - (ClinicalResearch@mmc.org) |
| Maine Medical Partners Surgical Care Portland, Maine | |
| MaineHealth Cancer Care and IV Therapy - Brunswick Brunswick, Maine | Site Public Contact - (clinicalresearch@mainehealth.org) |
| MaineHealth Cancer Care and IV Therapy - Sanford Sanford, Maine | Site Public Contact - (clinicalresearch@mainehealth.org) |
| MaineHealth Cancer Care and IV Therapy - South Portland South Portland, Maine | Site Public Contact - (clinicalresearch@mainehealth.org) |
| MaineHealth Franklin Hospital Farmington, Maine | Site Public Contact - (clinicalresearch@mainehealth.org) |
| MaineHealth LincolnHealth Hospital Damariscotta, Maine | Site Public Contact - (clinicalresearch@mainehealth.org) |
| MaineHealth Maine Medical Center - Biddeford Biddeford, Maine | |
| MaineHealth Maine Medical Center - Portland Portland, Maine | Site Public Contact - (clinicalresearch@mainehealth.org) |
| MaineHealth Maine Medical Center- Scarborough Scarborough, Maine | Site Public Contact - (clinicalresearch@mainehealth.org) |
| MaineHealth Stephens Hospital Norway, Maine | Site Public Contact - (clinicalresearch@mainehealth.org) |
| MaineHealth Urology - South Portland South Portland, Maine | Site Public Contact - (clinicalresearch@mainehealth.org) |
| MaineHealth Waldo Hospital Belfast, Maine | Site Public Contact - (clinicalresearch@mainehealth.org) |
| Marion L Shepard Cancer Center - ECU Health Beaufort Hospital Washington, North Carolina | Site Public Contact - (research@ecuhealth.org) |
| Marshfield Clinic - Wisconsin Rapids Center Wisconsin Rapids, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center - Minocqua Minocqua, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center - Weston Weston, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center-EC Cancer Center Eau Claire, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center-Marshfield Marshfield, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center-Rice Lake Rice Lake, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| Marshfield Medical Center-River Region at Stevens Point Stevens Point, Wisconsin | Site Public Contact - (oncology.clinical.trials@marshfieldresearch.org) |
| McFarland Clinic - Ames Ames, Iowa | Site Public Contact - (ksoder@mcfarlandclinic.com) |
| Mercy Clinic-Rolla-Cancer and Hematology Rolla, Missouri | |
| Mercy Hospital Fort Smith Fort Smith, Arkansas | |
| Mercy Hospital Joplin Joplin, Missouri | Site Public Contact - (esmeralda.carrillo@mercy.net) |
| Mercy Hospital Oklahoma City Oklahoma City, Oklahoma | |
| Mercy Hospital Saint Louis St Louis, Missouri | |
| Mercy Hospital South St Louis, Missouri | Site Public Contact - (Danielle.Werle@mercy.net) |
| Mercy Hospital Springfield Springfield, Missouri | |
| Mercy Hospital Washington Washington, Missouri | |
| Mercy Infusion Center - Chippewa St Louis, Missouri | |
| Mercy Oncology and Hematology - Clayton-Clarkson Ballwin, Missouri | |
| Mid Coast Hospital Brunswick, Maine | Site Public Contact - (ctsucontact@westat.com) |
| Missouri Baptist Medical Center St Louis, Missouri | |
| Mobile Infirmary Medical Center Mobile, Alabama | |
| Monongalia Hospital Morgantown, West Virginia | |
| Montefiore Medical Center - Moses Campus The Bronx, New York | Site Public Contact - (eskwak@montefiore.org) |
| Montefiore Medical Center-Einstein Campus The Bronx, New York | Site Public Contact - (eskwak@montefiore.org) |
| Montefiore Medical Center-Weiler Hospital The Bronx, New York | Site Public Contact - (eskwak@montefiore.org) |
| Morristown Medical Center Morristown, New Jersey | |
| NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center New York, New York | Site Public Contact - (cancerclinicaltrials@cumc.columbia.edu) |
| Nebraska Cancer Specialists/Oncology Hematology West PC Grand Island, Nebraska | |
| Newton Medical Center Newton, New Jersey | |
| North Star Lodge Cancer Center at Yakima Valley Memorial Hospital Yakima, Washington | Site Public Contact - (Memorial-ClinicalTrials@yvmh.org) |
| NorthShore University HealthSystem-Evanston Hospital Evanston, Illinois | |
| NorthShore University HealthSystem-Glenbrook Hospital Glenview, Illinois | |
| NorthShore University HealthSystem-Highland Park Hospital Highland Park, Illinois | |
| Northside Hospital Atlanta, Georgia | Site Public Contact - (ClinicalTrials@northside.com) |
| Novant Health Cancer Institute - Kernersville Kernersville, North Carolina | Site Public Contact - (asmarrs@novanthealth.org) |
| Novant Health Cancer Institute - Mount Airy Mount Airy, North Carolina | Site Public Contact - (asmarrs@novanthealth.org) |
| Novant Health Cancer Institute - Thomasville Thomasville, North Carolina | Site Public Contact - (pjordan@novanthealth.org) |
| Novant Health Forsyth Medical Center Winston-Salem, North Carolina | Site Public Contact - (pjordan@novanthealth.org) |
| Novant Health Presbyterian Medical Center Charlotte, North Carolina | |
| Oncology Associates at Mercy Medical Center Cedar Rapids, Iowa | |
| OptumCare Cancer Care at Charleston Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| OptumCare Cancer Care at Fort Apache Las Vegas, Nevada | Site Public Contact - (research@sncrf.org) |
| OptumCare Cancer Care at Seven Hills Henderson, Nevada | Site Public Contact - (research@sncrf.org) |
| Our Lady of the Lake Physician Group Baton Rouge, Louisiana | Site Public Contact - (research@ololrmc.com) |
| Overlook Hospital Summit, New Jersey | |
| PCR Oncology Arroyo Grande, California | Site Public Contact - (research@sncrf.org) |
| Penobscot Bay Medical Center Rockport, Maine | Site Public Contact - (clinicalresearch@mainehealth.org) |
| Phelps Health Delbert Day Cancer Institute Rolla, Missouri | Site Public Contact - (research@phelpshealth.org) |
| Physicians' Clinic of Iowa PC Cedar Rapids, Iowa | |
| Prisma Health Baptist Hospital Columbia, South Carolina | |
| Prisma Health Greenville Memorial Hospital Greenville, South Carolina | Site Public Contact - (Kim.Williams3@prismahealth.org) |
| Prisma Health Richland Hospital Columbia, South Carolina | Site Public Contact - (Kim.Williams3@prismahealth.org) |
| Roger Williams Medical Center Providence, Rhode Island | Site Public Contact - (fdallesandro@chartercare.org) |
| SMC Center for Hematology Oncology Union Union, South Carolina | Site Public Contact - (kmertz-rivera@gibbscc.org) |
| SSM Health Good Samaritan Mount Vernon, Illinois | Site Public Contact - (gayla.hall@ssmhealth.com) |
| Saint James Community Hospital and Cancer Treatment Center Butte, Montana | |
| Saint Joseph Hospital Lexington, Kentucky | Site Public Contact - (carcieri@sjh-nh.org) |
| Saint Joseph Hospital - Cancer Centers of Colorado Denver, Colorado | |
| Saint Mary's Hospital and Regional Medical Center Grand Junction, Colorado | Site Public Contact - (ccrp@co-cancerresearch.org) |
| Saint Mary's Regional Medical Center Reno, Nevada | |
| Saint Vincent Frontier Cancer Center Billings, Montana | |
| Salinas Valley Memorial Salinas, California | Site Public Contact - (tnielsen2@svmh.com) |
| San Juan City Hospital San Juan, | |
| San Juan Community Oncology Group San Juan, | |
| Spartanburg Medical Center Spartanburg, South Carolina | Site Public Contact - (kmertz-rivera@gibbscc.org) |
| Swedish Covenant Hospital Chicago, Illinois | |
| Tampa General Hospital Tampa, Florida | Site Public Contact - (syapchanyk@tgh.org) |
| Thomas Hospital Fairhope, Alabama | |
| Trinity Health Medical Center - Brighton Brighton, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Trinity Health Medical Center - Canton Canton, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Trinity Health Saint Joseph Mercy Hospital Ann Arbor Ann Arbor, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Trinity Health Saint Joseph Mercy Oakland Hospital Pontiac, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| Trinity Health Saint Mary Mercy Livonia Hospital Livonia, Michigan | Site Public Contact - (MCRCwebsitecontactform@stjoeshealth.org) |
| UI Health Care Mission Cancer and Blood - Des Moines Clinic Des Moines, Iowa | |
| University Medical Center New Orleans New Orleans, Louisiana | Site Public Contact - (emede1@lsuhsc.edu) |
| University of Iowa Healthcare Cancer Services Quad Cities Bettendorf, Iowa | Site Public Contact - (katherine-daprile@uiowa.edu) |
| University of Iowa/Holden Comprehensive Cancer Center Iowa City, Iowa | |
| VCU Massey Cancer Center at Stony Point Richmond, Virginia | Site Public Contact - (ctoclinops@vcu.edu) |
| VCU Massey Comprehensive Cancer Center Richmond, Virginia | Site Public Contact - (CTOclinops@vcu.edu) |
| Valley Medical Center Renton, Washington | Site Public Contact - (research@valleymed.org) |
| Veterans Affairs Loma Linda Healthcare System Loma Linda, California |