StudyFinder
Focusing on the Menopausal Transition to Improve Mid-Life Women's Health
RECRUITING
45 years to 55 years old
Inclusion Criteria:
* aged 45-55
* In the late menopausal transition, defined as 60 days of amenorrhea but less than 365 days of amenorrhea18
* No current use of hormone therapy or hormonal contraception
* Presence of a uterus and at least one ovary in order to track menstrual patterns
* Have a smartphone and broadband access adequate to accept telehealth appointments
Exclusion Criteria:
* Lack of broadband access (activity and survey data will be collected electronically whenever possible and some visits will be via telehealth)
* Lack of regular menstrual periods in mid-reproductive life (ages 25-38) when not on hormones or not pregnant.
* Pregnancy or actively trying to get pregnant
* Inability to adhere to study protocol schedule
* Untreated alcoholism
* Un- Diagnosed abnormal uterine bleeding
* Personal or family history of medullary thyroid cancer or multiple endocrine neoplasia (MEN 2) for participants with a BMI\> 30 kg/m2.DRUG: Metformin, DRUG: semaglutide, DRUG: Anti-hypertensives, DRUG: Lipid Lowering Medication, BEHAVIORAL: Life style intervention, DRUG: Fezolinetant, DRUG: Hormonal therapy
Menopause, Menopause Hot Flashes, Menopause Related Conditions, Cardiovascular
Carrie Hsu, BA - carrie.hsu@cuanschutz.edu
NCT06975111