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Screening for AL Amyloidosis in Smoldering Multiple Myeloma

RECRUITING
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40 years and over
This study is NOT accepting healthy volunteers
Inclusion Criteria:
* Patients 40 years of age and older * diagnosed with either Smoldering Multiple Myeloma or a Monoclonal Gammopathy * dFLC greater than 23 mg/L * abnormal FLC ratio * If the patient has an eGFR less than 50 mL/min/1.73m2, the FLC ratio is inconsequential. The patient only needs to meet the age and dFLC criterion.
Exclusion Criteria:
* Patients younger than 40 years of age are not eligible * Patients with a previous finding of amyloid in other biopsies will not be included * Adults unable to consent are not eligible, including the cognitively impaired Pregnant women, pregnant minors, minors (i.e., individuals who are not yet adults), wards of the state, non-viable neonates, neonates of uncertain viability, and prisoners are not eligible

Smoldering Multiple Myeloma

SMM, AL Amyloidosis

Raymond Comenzo, MD - raymond.comenzo@tuftsmedicine.org
NCT06365060

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